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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for SHOX

Z-value: 0.45

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Transcription factors associated with SHOX

Gene Symbol Gene ID Gene Info
SHOX
ENSG00000185960.8 short stature homeobox
SHOX
ENSGR0000185960.8 short stature homeobox

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SHOXhg19_v2_chrX_+_591524_591542-0.262.8e-01Click!

Activity profile of SHOX motif

Sorted Z-values of SHOX motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_+_52695617 1.18 ENST00000293525.5
KRT86
keratin 86
chr17_+_42634844 0.95 ENST00000315323.3
FZD2
frizzled family receptor 2
chr7_+_77428066 0.95 ENST00000422959.2
ENST00000307305.8
ENST00000424760.1
PHTF2
putative homeodomain transcription factor 2
chr3_+_149191723 0.92 ENST00000305354.4
TM4SF4
transmembrane 4 L six family member 4
chr11_+_123430948 0.90 ENST00000529432.1
ENST00000534764.1
GRAMD1B
GRAM domain containing 1B
chr10_+_94451574 0.89 ENST00000492654.2
HHEX
hematopoietically expressed homeobox
chr12_+_41136144 0.87 ENST00000548005.1
ENST00000552248.1
CNTN1
contactin 1
chrX_-_106243294 0.83 ENST00000255495.7
MORC4
MORC family CW-type zinc finger 4
chr19_+_48949087 0.82 ENST00000598711.1
GRWD1
glutamate-rich WD repeat containing 1
chr3_+_141106458 0.78 ENST00000509883.1
ZBTB38
zinc finger and BTB domain containing 38
chr6_-_127780510 0.78 ENST00000487331.2
ENST00000483725.3
KIAA0408
KIAA0408
chr12_+_78359999 0.77 ENST00000550503.1
NAV3
neuron navigator 3
chrX_-_106243451 0.74 ENST00000355610.4
ENST00000535534.1
MORC4
MORC family CW-type zinc finger 4
chr6_+_105404899 0.72 ENST00000345080.4
LIN28B
lin-28 homolog B (C. elegans)
chr7_+_77428149 0.72 ENST00000415251.2
ENST00000275575.7
PHTF2
putative homeodomain transcription factor 2
chr3_-_27764190 0.71 ENST00000537516.1
EOMES
eomesodermin
chr7_-_14029283 0.68 ENST00000433547.1
ENST00000405192.2
ETV1
ets variant 1
chr17_-_78450398 0.68 ENST00000306773.4
NPTX1
neuronal pentraxin I
chrX_-_71458802 0.68 ENST00000373657.1
ENST00000334463.3
ERCC6L
excision repair cross-complementing rodent repair deficiency, complementation group 6-like
chr7_-_14026123 0.67 ENST00000420159.2
ENST00000399357.3
ENST00000403527.1
ETV1
ets variant 1
chr13_-_67802549 0.67 ENST00000328454.5
ENST00000377865.2
PCDH9
protocadherin 9
chr14_+_67831576 0.65 ENST00000555876.1
EIF2S1
eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
chr4_-_40477766 0.62 ENST00000507180.1
RBM47
RNA binding motif protein 47
chr15_+_59910132 0.62 ENST00000559200.1
GCNT3
glucosaminyl (N-acetyl) transferase 3, mucin type
chr7_-_14026063 0.62 ENST00000443608.1
ENST00000438956.1
ETV1
ets variant 1
chr17_-_64225508 0.61 ENST00000205948.6
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr12_+_49621658 0.60 ENST00000541364.1
TUBA1C
tubulin, alpha 1c
chr12_+_20963632 0.59 ENST00000540853.1
ENST00000261196.2
SLCO1B3
solute carrier organic anion transporter family, member 1B3
chrX_-_20237059 0.58 ENST00000457145.1
RPS6KA3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr17_-_46690839 0.58 ENST00000498634.2
HOXB8
homeobox B8
chr4_+_169418195 0.58 ENST00000261509.6
ENST00000335742.7
PALLD
palladin, cytoskeletal associated protein
chr7_-_14029515 0.54 ENST00000430479.1
ENST00000405218.2
ENST00000343495.5
ETV1
ets variant 1
chr4_+_129731074 0.54 ENST00000512960.1
ENST00000503785.1
ENST00000514740.1
PHF17
jade family PHD finger 1
chr12_+_104680793 0.54 ENST00000529546.1
ENST00000529751.1
ENST00000540716.1
ENST00000528079.2
ENST00000526580.1
TXNRD1
thioredoxin reductase 1
chr10_-_7453445 0.53 ENST00000379713.3
ENST00000397167.1
ENST00000397160.3
SFMBT2
Scm-like with four mbt domains 2
chr3_+_141106643 0.52 ENST00000514251.1
ZBTB38
zinc finger and BTB domain containing 38
chr17_+_42785976 0.52 ENST00000393547.2
ENST00000398338.3
DBF4B
DBF4 homolog B (S. cerevisiae)
chrX_-_20236970 0.51 ENST00000379548.4
RPS6KA3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr1_+_66458072 0.51 ENST00000423207.2
PDE4B
phosphodiesterase 4B, cAMP-specific
chr10_+_35484793 0.51 ENST00000488741.1
ENST00000474931.1
ENST00000468236.1
ENST00000344351.5
ENST00000490511.1
CREM
cAMP responsive element modulator
chr10_+_90660832 0.51 ENST00000371924.1
STAMBPL1
STAM binding protein-like 1
chr8_+_98900132 0.51 ENST00000520016.1
MATN2
matrilin 2
chr7_-_55620433 0.51 ENST00000418904.1
VOPP1
vesicular, overexpressed in cancer, prosurvival protein 1
chr15_+_80351910 0.50 ENST00000261749.6
ENST00000561060.1
ZFAND6
zinc finger, AN1-type domain 6
chr19_+_48949030 0.50 ENST00000253237.5
GRWD1
glutamate-rich WD repeat containing 1
chr17_-_38821373 0.49 ENST00000394052.3
KRT222
keratin 222
chr17_+_57233087 0.48 ENST00000578777.1
ENST00000577457.1
ENST00000582995.1
PRR11
proline rich 11
chr9_-_123639445 0.48 ENST00000312189.6
PHF19
PHD finger protein 19
chr5_+_174151536 0.48 ENST00000239243.6
ENST00000507785.1
MSX2
msh homeobox 2
chr9_-_123812542 0.47 ENST00000223642.1
C5
complement component 5
chr10_-_33623310 0.47 ENST00000395995.1
ENST00000374823.5
ENST00000374821.5
ENST00000374816.3
NRP1
neuropilin 1
chr12_+_28410128 0.47 ENST00000381259.1
ENST00000381256.1
CCDC91
coiled-coil domain containing 91
chr5_-_59783882 0.46 ENST00000505507.2
ENST00000502484.2
PDE4D
phosphodiesterase 4D, cAMP-specific
chr4_+_41614909 0.45 ENST00000509454.1
ENST00000396595.3
ENST00000381753.4
LIMCH1
LIM and calponin homology domains 1
chr9_-_98189055 0.45 ENST00000433644.2
RP11-435O5.2
RP11-435O5.2
chr12_+_104680659 0.45 ENST00000526691.1
ENST00000531691.1
ENST00000388854.3
ENST00000354940.6
ENST00000526390.1
ENST00000531689.1
TXNRD1
thioredoxin reductase 1
chr12_+_20963647 0.45 ENST00000381545.3
SLCO1B3
solute carrier organic anion transporter family, member 1B3
chr12_-_102591604 0.45 ENST00000329406.4
PMCH
pro-melanin-concentrating hormone
chr8_+_42873548 0.45 ENST00000533338.1
ENST00000534420.1
HOOK3
RP11-598P20.5
hook microtubule-tethering protein 3
Uncharacterized protein
chrX_+_77166172 0.44 ENST00000343533.5
ENST00000350425.4
ENST00000341514.6
ATP7A
ATPase, Cu++ transporting, alpha polypeptide
chrX_-_19817869 0.44 ENST00000379698.4
SH3KBP1
SH3-domain kinase binding protein 1
chr17_-_77924627 0.44 ENST00000572862.1
ENST00000573782.1
ENST00000574427.1
ENST00000570373.1
ENST00000340848.7
ENST00000576768.1
TBC1D16
TBC1 domain family, member 16
chr11_-_31531121 0.43 ENST00000532287.1
ENST00000526776.1
ENST00000534812.1
ENST00000529749.1
ENST00000278200.1
ENST00000530023.1
ENST00000533642.1
IMMP1L
IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr1_-_151762943 0.43 ENST00000368825.3
ENST00000368823.1
ENST00000458431.2
ENST00000368827.6
ENST00000368824.3
TDRKH
tudor and KH domain containing
chr10_-_104866395 0.43 ENST00000458345.1
NT5C2
5'-nucleotidase, cytosolic II
chr10_-_36812323 0.42 ENST00000543053.1
NAMPTL
nicotinamide phosphoribosyltransferase-like
chr16_+_53133070 0.42 ENST00000565832.1
CHD9
chromodomain helicase DNA binding protein 9
chr3_-_157824292 0.41 ENST00000483851.2
SHOX2
short stature homeobox 2
chr18_+_32556892 0.41 ENST00000591734.1
ENST00000413393.1
ENST00000589180.1
ENST00000587359.1
MAPRE2
microtubule-associated protein, RP/EB family, member 2
chr1_-_151762900 0.41 ENST00000440583.2
TDRKH
tudor and KH domain containing
chr9_-_77643307 0.40 ENST00000376834.3
ENST00000376830.3
C9orf41
chromosome 9 open reading frame 41
chr20_-_25320367 0.40 ENST00000450393.1
ENST00000491682.1
ABHD12
abhydrolase domain containing 12
chr4_+_41614720 0.40 ENST00000509277.1
LIMCH1
LIM and calponin homology domains 1
chrX_-_153602991 0.40 ENST00000369850.3
ENST00000422373.1
FLNA
filamin A, alpha
chr14_-_64194745 0.40 ENST00000247225.6
SGPP1
sphingosine-1-phosphate phosphatase 1
chr3_-_27763803 0.40 ENST00000449599.1
EOMES
eomesodermin
chr12_-_52761262 0.39 ENST00000257901.3
KRT85
keratin 85
chr15_+_80351977 0.39 ENST00000559157.1
ENST00000561012.1
ENST00000564367.1
ENST00000558494.1
ZFAND6
zinc finger, AN1-type domain 6
chr21_-_35284635 0.38 ENST00000429238.1
AP000304.12
AP000304.12
chr17_-_48785216 0.38 ENST00000285243.6
ANKRD40
ankyrin repeat domain 40
chr1_+_206557366 0.37 ENST00000414007.1
ENST00000419187.2
SRGAP2
SLIT-ROBO Rho GTPase activating protein 2
chr7_-_77427676 0.37 ENST00000257663.3
TMEM60
transmembrane protein 60
chr1_-_101360374 0.37 ENST00000535414.1
EXTL2
exostosin-like glycosyltransferase 2
chr1_-_101360331 0.37 ENST00000416479.1
ENST00000370113.3
EXTL2
exostosin-like glycosyltransferase 2
chr6_+_126221034 0.37 ENST00000433571.1
NCOA7
nuclear receptor coactivator 7
chr2_-_61697862 0.37 ENST00000398571.2
USP34
ubiquitin specific peptidase 34
chr5_+_137722255 0.37 ENST00000542866.1
KDM3B
lysine (K)-specific demethylase 3B
chrX_+_108779004 0.36 ENST00000218004.1
NXT2
nuclear transport factor 2-like export factor 2
chr1_-_21625486 0.36 ENST00000481130.2
ECE1
endothelin converting enzyme 1
chr1_+_180601139 0.36 ENST00000367590.4
ENST00000367589.3
XPR1
xenotropic and polytropic retrovirus receptor 1
chr3_-_33686925 0.36 ENST00000485378.2
ENST00000313350.6
ENST00000487200.1
CLASP2
cytoplasmic linker associated protein 2
chr13_+_78315295 0.34 ENST00000351546.3
SLAIN1
SLAIN motif family, member 1
chr4_+_129732419 0.34 ENST00000510308.1
PHF17
jade family PHD finger 1
chr13_+_36050881 0.34 ENST00000537702.1
NBEA
neurobeachin
chr2_+_109204743 0.34 ENST00000332345.6
LIMS1
LIM and senescent cell antigen-like domains 1
chr2_-_44550441 0.33 ENST00000420756.1
ENST00000444696.1
PREPL
prolyl endopeptidase-like
chr6_+_52535878 0.33 ENST00000211314.4
TMEM14A
transmembrane protein 14A
chr3_+_69985734 0.33 ENST00000314557.6
ENST00000394351.3
MITF
microphthalmia-associated transcription factor
chr3_+_141105705 0.33 ENST00000513258.1
ZBTB38
zinc finger and BTB domain containing 38
chr12_-_54653313 0.33 ENST00000550411.1
ENST00000439541.2
CBX5
chromobox homolog 5
chr3_-_131756559 0.33 ENST00000505957.1
CPNE4
copine IV
chr6_-_37665751 0.33 ENST00000297153.7
ENST00000434837.3
MDGA1
MAM domain containing glycosylphosphatidylinositol anchor 1
chr3_-_149293990 0.33 ENST00000472417.1
WWTR1
WW domain containing transcription regulator 1
chr2_+_190541153 0.32 ENST00000313581.4
ENST00000438402.2
ENST00000431575.2
ENST00000281412.6
ANKAR
ankyrin and armadillo repeat containing
chr17_-_2117600 0.32 ENST00000572369.1
SMG6
SMG6 nonsense mediated mRNA decay factor
chr14_-_51027838 0.32 ENST00000555216.1
MAP4K5
mitogen-activated protein kinase kinase kinase kinase 5
chr3_-_167191814 0.32 ENST00000466903.1
ENST00000264677.4
SERPINI2
serpin peptidase inhibitor, clade I (pancpin), member 2
chr7_-_99716940 0.31 ENST00000440225.1
TAF6
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr7_+_116502605 0.31 ENST00000458284.2
ENST00000490693.1
CAPZA2
capping protein (actin filament) muscle Z-line, alpha 2
chrX_-_10851762 0.30 ENST00000380785.1
ENST00000380787.1
MID1
midline 1 (Opitz/BBB syndrome)
chr1_-_232651312 0.30 ENST00000262861.4
SIPA1L2
signal-induced proliferation-associated 1 like 2
chr17_+_19091325 0.30 ENST00000584923.1
SNORD3A
small nucleolar RNA, C/D box 3A
chr12_-_56694083 0.30 ENST00000552688.1
ENST00000548041.1
ENST00000551137.1
ENST00000551968.1
ENST00000542324.2
ENST00000546930.1
ENST00000549221.1
ENST00000550159.1
ENST00000550734.1
CS
citrate synthase
chr6_+_4087664 0.30 ENST00000430835.2
C6orf201
chromosome 6 open reading frame 201
chr6_-_97731019 0.29 ENST00000275053.4
MMS22L
MMS22-like, DNA repair protein
chrX_-_153599578 0.29 ENST00000360319.4
ENST00000344736.4
FLNA
filamin A, alpha
chr5_+_162930114 0.29 ENST00000280969.5
MAT2B
methionine adenosyltransferase II, beta
chr4_+_95916947 0.29 ENST00000506363.1
BMPR1B
bone morphogenetic protein receptor, type IB
chr1_+_226013047 0.29 ENST00000366837.4
EPHX1
epoxide hydrolase 1, microsomal (xenobiotic)
chr8_-_90996837 0.28 ENST00000519426.1
ENST00000265433.3
NBN
nibrin
chr2_-_28113965 0.28 ENST00000302188.3
RBKS
ribokinase
chr17_-_39341594 0.28 ENST00000398472.1
KRTAP4-1
keratin associated protein 4-1
chr12_-_31478428 0.28 ENST00000543615.1
FAM60A
family with sequence similarity 60, member A
chr17_-_38956205 0.28 ENST00000306658.7
KRT28
keratin 28
chr2_-_65593784 0.28 ENST00000443619.2
SPRED2
sprouty-related, EVH1 domain containing 2
chr5_+_136070614 0.28 ENST00000502421.1
CTB-1I21.1
CTB-1I21.1
chr17_-_46716647 0.27 ENST00000608940.1
RP11-357H14.17
RP11-357H14.17
chr19_+_34287751 0.27 ENST00000590771.1
ENST00000589786.1
ENST00000284006.6
ENST00000588881.1
KCTD15
potassium channel tetramerization domain containing 15
chr1_-_159832438 0.27 ENST00000368100.1
VSIG8
V-set and immunoglobulin domain containing 8
chr5_-_159827033 0.27 ENST00000523213.1
C5orf54
chromosome 5 open reading frame 54
chr12_-_56693758 0.27 ENST00000547298.1
ENST00000551936.1
ENST00000551253.1
ENST00000551473.1
CS
citrate synthase
chr8_-_17533838 0.27 ENST00000400046.1
MTUS1
microtubule associated tumor suppressor 1
chr3_-_178103144 0.27 ENST00000417383.1
ENST00000418585.1
ENST00000411727.1
ENST00000439810.1
RP11-33A14.1
RP11-33A14.1
chr20_+_3776371 0.27 ENST00000245960.5
CDC25B
cell division cycle 25B
chr8_-_102803163 0.26 ENST00000523645.1
ENST00000520346.1
ENST00000220931.6
ENST00000522448.1
ENST00000522951.1
ENST00000522252.1
ENST00000519098.1
NCALD
neurocalcin delta
chr2_-_55647057 0.26 ENST00000436346.1
CCDC88A
coiled-coil domain containing 88A
chr12_+_54378923 0.26 ENST00000303460.4
HOXC10
homeobox C10
chr16_-_18887627 0.26 ENST00000563235.1
SMG1
SMG1 phosphatidylinositol 3-kinase-related kinase
chr2_+_143635067 0.26 ENST00000264170.4
KYNU
kynureninase
chr3_+_157154578 0.26 ENST00000295927.3
PTX3
pentraxin 3, long
chr2_+_152214098 0.25 ENST00000243347.3
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr15_+_36887069 0.25 ENST00000566807.1
ENST00000567389.1
ENST00000562877.1
C15orf41
chromosome 15 open reading frame 41
chr12_+_52056548 0.25 ENST00000545061.1
ENST00000355133.3
SCN8A
sodium channel, voltage gated, type VIII, alpha subunit
chr9_+_82188077 0.25 ENST00000425506.1
TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr14_-_21994337 0.25 ENST00000537235.1
ENST00000450879.2
SALL2
spalt-like transcription factor 2
chr20_+_18488137 0.25 ENST00000450074.1
ENST00000262544.2
ENST00000336714.3
ENST00000377475.3
SEC23B
Sec23 homolog B (S. cerevisiae)
chr3_+_111393501 0.25 ENST00000393934.3
PLCXD2
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr16_-_28192360 0.24 ENST00000570033.1
XPO6
exportin 6
chr2_-_55646957 0.24 ENST00000263630.8
CCDC88A
coiled-coil domain containing 88A
chr20_+_42544782 0.24 ENST00000423191.2
ENST00000372999.1
TOX2
TOX high mobility group box family member 2
chr8_+_101170563 0.24 ENST00000520508.1
ENST00000388798.2
SPAG1
sperm associated antigen 1
chr1_-_101360205 0.24 ENST00000450240.1
EXTL2
exostosin-like glycosyltransferase 2
chr2_+_172309634 0.24 ENST00000339506.3
DCAF17
DDB1 and CUL4 associated factor 17
chr7_-_130066571 0.24 ENST00000492389.1
CEP41
centrosomal protein 41kDa
chr4_+_146402346 0.24 ENST00000514778.1
ENST00000507594.1
SMAD1
SMAD family member 1
chr12_-_118796910 0.24 ENST00000541186.1
ENST00000539872.1
TAOK3
TAO kinase 3
chr1_-_36020531 0.24 ENST00000440579.1
ENST00000494948.1
KIAA0319L
KIAA0319-like
chr16_-_29910853 0.24 ENST00000308713.5
SEZ6L2
seizure related 6 homolog (mouse)-like 2
chr7_-_23510086 0.23 ENST00000258729.3
IGF2BP3
insulin-like growth factor 2 mRNA binding protein 3
chr4_+_169418255 0.23 ENST00000505667.1
ENST00000511948.1
PALLD
palladin, cytoskeletal associated protein
chr13_+_78315348 0.23 ENST00000441784.1
SLAIN1
SLAIN motif family, member 1
chr2_-_190446738 0.23 ENST00000427419.1
ENST00000455320.1
SLC40A1
solute carrier family 40 (iron-regulated transporter), member 1
chr1_-_242612726 0.22 ENST00000459864.1
PLD5
phospholipase D family, member 5
chr16_+_103816 0.22 ENST00000383018.3
ENST00000417493.1
SNRNP25
small nuclear ribonucleoprotein 25kDa (U11/U12)
chr2_-_216946500 0.22 ENST00000265322.7
PECR
peroxisomal trans-2-enoyl-CoA reductase
chr10_-_27529486 0.22 ENST00000375888.1
ACBD5
acyl-CoA binding domain containing 5
chr6_-_76072719 0.22 ENST00000370020.1
FILIP1
filamin A interacting protein 1
chr3_-_33686743 0.22 ENST00000333778.6
ENST00000539981.1
CLASP2
cytoplasmic linker associated protein 2
chr17_+_56833184 0.22 ENST00000308249.2
PPM1E
protein phosphatase, Mg2+/Mn2+ dependent, 1E
chr20_+_18447771 0.21 ENST00000377603.4
POLR3F
polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa
chr7_+_116502527 0.21 ENST00000361183.3
CAPZA2
capping protein (actin filament) muscle Z-line, alpha 2
chr9_-_136933615 0.21 ENST00000371834.2
BRD3
bromodomain containing 3
chr8_-_90996459 0.21 ENST00000517337.1
ENST00000409330.1
NBN
nibrin
chr2_-_136633940 0.21 ENST00000264156.2
MCM6
minichromosome maintenance complex component 6
chr7_-_37488777 0.21 ENST00000445322.1
ENST00000448602.1
ELMO1
engulfment and cell motility 1
chr2_+_216946589 0.21 ENST00000433112.1
ENST00000454545.1
ENST00000437356.2
ENST00000295658.4
ENST00000455479.1
ENST00000406027.2
TMEM169
transmembrane protein 169
chrX_-_46187069 0.21 ENST00000446884.1
RP1-30G7.2
RP1-30G7.2
chr1_-_224624730 0.21 ENST00000445239.1
WDR26
WD repeat domain 26
chr4_+_105828537 0.21 ENST00000515649.1
RP11-556I14.1
RP11-556I14.1
chr13_+_78315466 0.21 ENST00000314070.5
ENST00000462234.1
SLAIN1
SLAIN motif family, member 1
chr5_+_118668846 0.21 ENST00000513374.1
TNFAIP8
tumor necrosis factor, alpha-induced protein 8
chr3_-_191000172 0.20 ENST00000427544.2
UTS2B
urotensin 2B
chr12_-_14133053 0.20 ENST00000609686.1
GRIN2B
glutamate receptor, ionotropic, N-methyl D-aspartate 2B
chr7_-_111424506 0.20 ENST00000450156.1
ENST00000494651.2
DOCK4
dedicator of cytokinesis 4
chr20_+_43990576 0.20 ENST00000372727.1
ENST00000414310.1
SYS1
SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)
chr15_-_37393406 0.20 ENST00000338564.5
ENST00000558313.1
ENST00000340545.5
MEIS2
Meis homeobox 2
chr2_-_74618907 0.20 ENST00000421392.1
ENST00000437375.1
DCTN1
dynactin 1
chr7_+_116660246 0.20 ENST00000434836.1
ENST00000393443.1
ENST00000465133.1
ENST00000477742.1
ENST00000393447.4
ENST00000393444.3
ST7
suppression of tumorigenicity 7
chr2_-_136678123 0.20 ENST00000422708.1
DARS
aspartyl-tRNA synthetase
chr3_+_69928256 0.20 ENST00000394355.2
MITF
microphthalmia-associated transcription factor
chr17_-_62499334 0.20 ENST00000579996.1
DDX5
DEAD (Asp-Glu-Ala-Asp) box helicase 5
chr10_-_21806759 0.20 ENST00000444772.3
SKIDA1
SKI/DACH domain containing 1
chr8_+_22424551 0.20 ENST00000523348.1
SORBS3
sorbin and SH3 domain containing 3
chr13_+_110958124 0.19 ENST00000400163.2
COL4A2
collagen, type IV, alpha 2
chr2_-_145277569 0.19 ENST00000303660.4
ZEB2
zinc finger E-box binding homeobox 2
chrX_+_123097014 0.19 ENST00000394478.1
STAG2
stromal antigen 2
chr17_+_39405939 0.19 ENST00000334109.2
KRTAP9-4
keratin associated protein 9-4
chr21_+_30673091 0.19 ENST00000447177.1
BACH1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr2_-_74618964 0.19 ENST00000417090.1
ENST00000409868.1
DCTN1
dynactin 1
chr16_+_14280742 0.19 ENST00000341243.5
MKL2
MKL/myocardin-like 2

Network of associatons between targets according to the STRING database.

First level regulatory network of SHOX

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0010621 negative regulation of transcription by transcription factor localization(GO:0010621) gall bladder development(GO:0061010)
0.2 0.7 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.2 1.1 GO:0060809 mesodermal to mesenchymal transition involved in gastrulation(GO:0060809)
0.2 0.6 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.2 0.5 GO:0051795 positive regulation of catagen(GO:0051795) activation of meiosis(GO:0090427)
0.2 0.6 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.1 0.5 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.1 0.4 GO:0042414 epinephrine metabolic process(GO:0042414) cellular response to lead ion(GO:0071284)
0.1 0.4 GO:0046462 monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.1 0.5 GO:0061552 vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.1 0.4 GO:0003363 lamellipodium assembly involved in ameboidal cell migration(GO:0003363) extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration(GO:0021816)
0.1 1.0 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1 2.7 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.1 0.5 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.1 0.4 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.1 0.5 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.1 0.2 GO:1903414 spleen trabecula formation(GO:0060345) iron cation export(GO:1903414) ferrous iron export(GO:1903988)
0.1 1.0 GO:0001887 selenium compound metabolic process(GO:0001887)
0.1 1.0 GO:0060022 hard palate development(GO:0060022)
0.1 0.3 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 0.7 GO:0010587 miRNA catabolic process(GO:0010587)
0.1 1.0 GO:1901078 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 0.3 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.1 0.4 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.1 0.5 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.1 0.4 GO:0010814 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.1 0.3 GO:0019303 D-ribose catabolic process(GO:0019303)
0.1 0.3 GO:0097264 self proteolysis(GO:0097264)
0.1 0.5 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.1 0.6 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.1 0.6 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.2 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.1 GO:0033025 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.0 0.3 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 0.3 GO:0052199 negative regulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052199)
0.0 0.1 GO:2001190 positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
0.0 0.3 GO:0048165 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0 0.5 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.4 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.0 0.4 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.0 0.2 GO:0072101 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.0 0.5 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 1.3 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.2 GO:0021993 initiation of neural tube closure(GO:0021993)
0.0 0.8 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.2 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.0 0.1 GO:0043049 hepatocyte cell migration(GO:0002194) otic placode formation(GO:0043049) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.0 0.5 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.0 0.6 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 0.2 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.0 0.2 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.0 0.2 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0 0.4 GO:2000172 regulation of branching morphogenesis of a nerve(GO:2000172)
0.0 0.2 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.0 0.1 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) negative regulation of neuromuscular junction development(GO:1904397)
0.0 0.1 GO:0021530 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.0 0.1 GO:0006667 sphinganine metabolic process(GO:0006667)
0.0 0.2 GO:0036371 protein localization to T-tubule(GO:0036371)
0.0 1.1 GO:0043555 regulation of translation in response to stress(GO:0043555)
0.0 0.8 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.3 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.5 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 0.7 GO:0021516 dorsal spinal cord development(GO:0021516)
0.0 0.6 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.6 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.3 GO:1904354 negative regulation of telomere capping(GO:1904354)
0.0 0.4 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.4 GO:0072718 response to cisplatin(GO:0072718)
0.0 0.4 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.1 GO:0042421 norepinephrine biosynthetic process(GO:0042421)
0.0 0.2 GO:0030242 pexophagy(GO:0030242)
0.0 0.9 GO:0072663 protein targeting to peroxisome(GO:0006625) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.0 0.1 GO:0036509 trimming of terminal mannose on B branch(GO:0036509) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512)
0.0 1.0 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.1 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.1 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
0.0 0.2 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.2 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.2 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.3 GO:0007144 female meiosis I(GO:0007144)
0.0 0.2 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.0 0.2 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.3 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.2 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.0 0.1 GO:0015722 canalicular bile acid transport(GO:0015722) pyrimidine nucleobase transport(GO:0015855) purine nucleobase transmembrane transport(GO:1904823)
0.0 0.3 GO:0072257 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.0 0.1 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.1 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.0 0.1 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.1 GO:0035553 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.0 0.1 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.2 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.0 0.1 GO:0035701 hematopoietic stem cell migration(GO:0035701)
0.0 0.2 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 0.2 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.1 GO:0000354 cis assembly of pre-catalytic spliceosome(GO:0000354)
0.0 0.1 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.0 0.1 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.0 0.0 GO:0061743 motor learning(GO:0061743)
0.0 0.3 GO:0045109 intermediate filament organization(GO:0045109)
0.0 0.2 GO:0061734 parkin-mediated mitophagy in response to mitochondrial depolarization(GO:0061734)
0.0 0.1 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.0 0.5 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.0 GO:0006480 N-terminal protein amino acid methylation(GO:0006480)
0.0 0.7 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.0 GO:0060922 atrioventricular node development(GO:0003162) cardiac septum cell differentiation(GO:0003292) atrioventricular node cell differentiation(GO:0060922) atrioventricular node cell development(GO:0060928)
0.0 0.1 GO:0050955 thermoception(GO:0050955)
0.0 0.5 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.2 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.1 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0043614 multi-eIF complex(GO:0043614) translation preinitiation complex(GO:0070993) glial limiting end-foot(GO:0097451)
0.2 0.7 GO:0031523 Myb complex(GO:0031523)
0.2 0.8 GO:0071547 piP-body(GO:0071547)
0.2 0.5 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 0.3 GO:0035101 FACT complex(GO:0035101)
0.1 0.3 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.1 0.3 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.1 0.4 GO:0031302 intrinsic component of endosome membrane(GO:0031302)
0.1 0.5 GO:0005579 membrane attack complex(GO:0005579)
0.1 0.2 GO:0043257 laminin-8 complex(GO:0043257)
0.0 0.5 GO:0097443 sorting endosome(GO:0097443)
0.0 0.5 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.6 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.6 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.5 GO:0005869 dynactin complex(GO:0005869)
0.0 0.1 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.4 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.5 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 2.3 GO:0045095 keratin filament(GO:0045095)
0.0 0.6 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 0.1 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.0 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.2 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 0.3 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.0 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.3 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.1 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.0 0.3 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.5 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.8 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.3 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.4 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.2 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.1 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 0.5 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 1.1 GO:0016235 aggresome(GO:0016235)
0.0 0.4 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.4 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.0 GO:0035841 new growing cell tip(GO:0035841)
0.0 0.5 GO:0031301 integral component of organelle membrane(GO:0031301)
0.0 0.5 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.2 GO:0042555 MCM complex(GO:0042555)
0.0 0.1 GO:0036021 endolysosome lumen(GO:0036021)
0.0 0.9 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 0.1 GO:1990246 uniplex complex(GO:1990246)
0.0 0.2 GO:0030127 COPII vesicle coat(GO:0030127)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0035248 alpha-1,4-N-acetylgalactosaminyltransferase activity(GO:0035248)
0.2 0.7 GO:0036440 citrate (Si)-synthase activity(GO:0004108) citrate synthase activity(GO:0036440)
0.2 0.6 GO:0047225 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0047225)
0.2 1.0 GO:0098626 methylselenol reductase activity(GO:0098625) methylseleninic acid reductase activity(GO:0098626)
0.1 0.4 GO:0050146 nucleoside phosphotransferase activity(GO:0050146)
0.1 0.6 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.1 0.4 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532) copper-dependent protein binding(GO:0032767)
0.1 0.4 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.7 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.1 0.3 GO:0033961 cis-stilbene-oxide hydrolase activity(GO:0033961)
0.1 0.4 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.1 0.2 GO:0097689 iron channel activity(GO:0097689)
0.1 0.2 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.1 1.3 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.3 GO:0016823 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0 1.6 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.6 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.0 0.9 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 1.0 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.1 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.0 0.1 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.0 0.2 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.6 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.8 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.1 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.0 0.3 GO:0046790 virion binding(GO:0046790)
0.0 0.9 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.5 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.5 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.3 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.2 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.2 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 1.3 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.4 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.2 GO:0035500 MH2 domain binding(GO:0035500)
0.0 1.0 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.5 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.4 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.1 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.1 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.0 0.5 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.2 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.2 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.0 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.1 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0 1.0 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.4 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.3 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.1 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.6 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.6 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.1 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.0 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
0.0 0.3 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.1 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.5 GO:0008009 chemokine activity(GO:0008009)
0.0 0.1 GO:0048156 tau protein binding(GO:0048156)
0.0 0.2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.8 GO:0031593 polyubiquitin binding(GO:0031593)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.9 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 1.0 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.5 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 1.1 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.6 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.3 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 1.1 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.2 PID ALK2 PATHWAY ALK2 signaling events
0.0 1.1 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.4 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 0.7 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.4 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.7 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 1.0 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.5 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 1.3 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS Genes involved in CREB phosphorylation through the activation of Ras
0.0 0.5 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.9 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.2 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.6 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 1.0 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.5 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.6 REACTOME PERK REGULATED GENE EXPRESSION Genes involved in PERK regulated gene expression
0.0 0.3 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.5 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.3 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.3 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.2 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.2 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.1 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle