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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for SIX5_SMARCC2_HCFC1

Z-value: 1.35

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Transcription factors associated with SIX5_SMARCC2_HCFC1

Gene Symbol Gene ID Gene Info
SIX5
ENSG00000177045.6 SIX homeobox 5
SMARCC2
ENSG00000139613.7 SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2
HCFC1
ENSG00000172534.9 host cell factor C1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SIX5hg19_v2_chr19_-_46272462_462725620.784.4e-05Click!
HCFC1hg19_v2_chrX_-_153236819_1532369780.776.9e-05Click!
SMARCC2hg19_v2_chr12_-_56583332_565833690.126.0e-01Click!

Activity profile of SIX5_SMARCC2_HCFC1 motif

Sorted Z-values of SIX5_SMARCC2_HCFC1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_47551836 3.65 ENST00000253047.6
TMEM160
transmembrane protein 160
chr19_-_51014345 3.38 ENST00000391815.3
ENST00000594350.1
ENST00000601423.1
JOSD2
Josephin domain containing 2
chr19_-_51014460 3.00 ENST00000595669.1
JOSD2
Josephin domain containing 2
chr19_-_51014588 2.94 ENST00000598418.1
JOSD2
Josephin domain containing 2
chr19_+_51152702 2.81 ENST00000425202.1
C19orf81
chromosome 19 open reading frame 81
chr1_-_247095236 2.41 ENST00000478568.1
AHCTF1
AT hook containing transcription factor 1
chr2_+_38893047 2.35 ENST00000272252.5
GALM
galactose mutarotase (aldose 1-epimerase)
chr19_-_51611623 2.33 ENST00000421832.2
CTU1
cytosolic thiouridylase subunit 1
chr19_+_50169081 2.28 ENST00000246784.3
BCL2L12
BCL2-like 12 (proline rich)
chr2_+_38893208 2.28 ENST00000410063.1
GALM
galactose mutarotase (aldose 1-epimerase)
chr16_-_2205352 2.10 ENST00000563192.1
RP11-304L19.5
RP11-304L19.5
chr19_+_50169216 2.09 ENST00000594157.1
ENST00000600947.1
ENST00000598306.1
BCL2L12
BCL2-like 12 (proline rich)
chr11_+_61560348 2.06 ENST00000535723.1
ENST00000574708.1
FEN1
FADS2
flap structure-specific endonuclease 1
fatty acid desaturase 2
chr19_-_42463418 2.01 ENST00000600292.1
ENST00000601078.1
ENST00000601891.1
ENST00000222008.6
RABAC1
Rab acceptor 1 (prenylated)
chr16_-_3073933 1.98 ENST00000574151.1
HCFC1R1
host cell factor C1 regulator 1 (XPO1 dependent)
chr19_+_3185910 1.93 ENST00000588428.1
NCLN
nicalin
chr16_-_70472946 1.85 ENST00000342907.2
ST3GAL2
ST3 beta-galactoside alpha-2,3-sialyltransferase 2
chr19_+_38397839 1.73 ENST00000222345.6
SIPA1L3
signal-induced proliferation-associated 1 like 3
chr2_+_27070964 1.69 ENST00000288699.6
DPYSL5
dihydropyrimidinase-like 5
chr15_+_40453204 1.68 ENST00000287598.6
ENST00000412359.3
BUB1B
BUB1 mitotic checkpoint serine/threonine kinase B
chr16_-_3074231 1.65 ENST00000572355.1
ENST00000248089.3
ENST00000574980.1
ENST00000354679.3
ENST00000396916.1
ENST00000573842.1
HCFC1R1
host cell factor C1 regulator 1 (XPO1 dependent)
chr17_+_73780852 1.64 ENST00000589666.1
UNK
unkempt family zinc finger
chr4_+_1723197 1.61 ENST00000485989.2
ENST00000313288.4
TACC3
transforming, acidic coiled-coil containing protein 3
chr16_+_3074002 1.60 ENST00000326266.8
ENST00000574549.1
ENST00000575576.1
ENST00000253952.9
THOC6
THO complex 6 homolog (Drosophila)
chr1_-_1051455 1.57 ENST00000379339.1
ENST00000480643.1
ENST00000434641.1
ENST00000421241.2
C1orf159
chromosome 1 open reading frame 159
chr19_+_42746927 1.55 ENST00000378108.1
AC006486.1
AC006486.1
chr9_-_130700080 1.55 ENST00000373110.4
DPM2
dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit
chr17_-_7760457 1.54 ENST00000576384.1
LSMD1
LSM domain containing 1
chr20_+_62694461 1.53 ENST00000343484.5
ENST00000395053.3
TCEA2
transcription elongation factor A (SII), 2
chr16_+_577697 1.49 ENST00000562370.1
ENST00000568988.1
ENST00000219611.2
CAPN15
calpain 15
chr17_-_73937116 1.48 ENST00000586717.1
ENST00000389570.4
ENST00000319129.5
FBF1
Fas (TNFRSF6) binding factor 1
chr17_-_7760779 1.44 ENST00000335155.5
ENST00000575071.1
LSMD1
LSM domain containing 1
chr3_+_50388126 1.43 ENST00000425346.1
ENST00000424512.1
ENST00000232508.5
ENST00000418577.1
ENST00000606589.1
CYB561D2
XXcos-LUCA11.5
cytochrome b561 family, member D2
Uncharacterized protein
chr11_-_65488260 1.43 ENST00000527610.1
ENST00000528220.1
ENST00000308418.4
RNASEH2C
ribonuclease H2, subunit C
chr19_-_49016847 1.39 ENST00000598924.1
CTC-273B12.10
CTC-273B12.10
chr12_-_6961050 1.37 ENST00000538862.2
CDCA3
cell division cycle associated 3
chr17_+_43239231 1.34 ENST00000591576.1
ENST00000591070.1
ENST00000592695.1
HEXIM2
hexamethylene bis-acetamide inducible 2
chr19_+_56652643 1.32 ENST00000586123.1
ZNF444
zinc finger protein 444
chr17_-_17494972 1.31 ENST00000435340.2
ENST00000255389.5
ENST00000395781.2
PEMT
phosphatidylethanolamine N-methyltransferase
chr1_+_244816371 1.30 ENST00000263831.7
DESI2
desumoylating isopeptidase 2
chr2_+_27071045 1.29 ENST00000401478.1
DPYSL5
dihydropyrimidinase-like 5
chr15_+_75315896 1.27 ENST00000342932.3
ENST00000564923.1
ENST00000569562.1
ENST00000568649.1
PPCDC
phosphopantothenoylcysteine decarboxylase
chr16_-_2097787 1.25 ENST00000566380.1
ENST00000219066.1
NTHL1
nth endonuclease III-like 1 (E. coli)
chr2_+_27593389 1.25 ENST00000233575.2
ENST00000543024.1
ENST00000537606.1
SNX17
sorting nexin 17
chr1_-_1051736 1.23 ENST00000448924.1
ENST00000294576.5
ENST00000437760.1
ENST00000462097.1
ENST00000475119.1
C1orf159
chromosome 1 open reading frame 159
chr16_+_30934376 1.22 ENST00000562798.1
ENST00000471231.2
FBXL19
F-box and leucine-rich repeat protein 19
chr17_+_7123207 1.20 ENST00000584103.1
ENST00000579886.2
ACADVL
acyl-CoA dehydrogenase, very long chain
chr10_-_69597915 1.18 ENST00000225171.2
DNAJC12
DnaJ (Hsp40) homolog, subfamily C, member 12
chr2_+_197504278 1.16 ENST00000272831.7
ENST00000389175.4
ENST00000472405.2
ENST00000423093.2
CCDC150
coiled-coil domain containing 150
chr19_+_35168547 1.16 ENST00000502743.1
ENST00000509528.1
ENST00000506901.1
ZNF302
zinc finger protein 302
chr19_-_47354082 1.15 ENST00000593442.1
ENST00000263270.6
AP2S1
adaptor-related protein complex 2, sigma 1 subunit
chrX_+_49091920 1.15 ENST00000376227.3
CCDC22
coiled-coil domain containing 22
chr1_+_149871171 1.14 ENST00000369150.1
BOLA1
bolA family member 1
chr19_+_39390320 1.12 ENST00000576510.1
NFKBIB
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
chr8_-_38326139 1.11 ENST00000335922.5
ENST00000532791.1
ENST00000397091.5
FGFR1
fibroblast growth factor receptor 1
chr10_+_104614008 1.11 ENST00000369883.3
C10orf32
chromosome 10 open reading frame 32
chr1_-_156542328 1.11 ENST00000361170.2
IQGAP3
IQ motif containing GTPase activating protein 3
chr5_+_175815732 1.10 ENST00000274787.2
HIGD2A
HIG1 hypoxia inducible domain family, member 2A
chr8_-_145669791 1.09 ENST00000409379.3
TONSL
tonsoku-like, DNA repair protein
chr12_+_53662073 1.08 ENST00000553219.1
ENST00000257934.4
ESPL1
extra spindle pole bodies homolog 1 (S. cerevisiae)
chr15_-_64386120 1.07 ENST00000300030.3
FAM96A
family with sequence similarity 96, member A
chr17_+_76210267 1.07 ENST00000301633.4
ENST00000350051.3
ENST00000374948.2
ENST00000590449.1
BIRC5
baculoviral IAP repeat containing 5
chr8_-_38326119 1.06 ENST00000356207.5
ENST00000326324.6
FGFR1
fibroblast growth factor receptor 1
chr17_+_43239191 1.06 ENST00000589230.1
HEXIM2
hexamethylene bis-acetamide inducible 2
chr3_+_133524459 1.06 ENST00000484684.1
SRPRB
signal recognition particle receptor, B subunit
chr16_+_70488480 1.05 ENST00000572784.1
ENST00000574784.1
ENST00000571514.1
ENST00000378912.2
ENST00000428974.2
ENST00000573352.1
ENST00000576453.1
FUK
fucokinase
chr16_+_67876180 1.04 ENST00000303596.1
THAP11
THAP domain containing 11
chr11_-_61560053 1.04 ENST00000537328.1
TMEM258
transmembrane protein 258
chr22_-_30162924 1.04 ENST00000344318.3
ENST00000397781.3
ZMAT5
zinc finger, matrin-type 5
chr16_+_30709530 1.03 ENST00000411466.2
SRCAP
Snf2-related CREBBP activator protein
chr2_+_27071292 1.03 ENST00000431402.1
ENST00000434719.1
DPYSL5
dihydropyrimidinase-like 5
chr1_+_149871135 1.02 ENST00000369152.5
BOLA1
bolA family member 1
chr1_+_242011485 1.02 ENST00000423131.1
ENST00000523590.1
EXO1
exonuclease 1
chr10_+_64564469 1.02 ENST00000373783.1
ADO
2-aminoethanethiol (cysteamine) dioxygenase
chr7_+_150725510 1.01 ENST00000461373.1
ENST00000358849.4
ENST00000297504.6
ENST00000542328.1
ENST00000498578.1
ENST00000356058.4
ENST00000477719.1
ENST00000477092.1
ABCB8
ATP-binding cassette, sub-family B (MDR/TAP), member 8
chr9_+_130965651 0.99 ENST00000475805.1
ENST00000341179.7
ENST00000372923.3
DNM1
dynamin 1
chr17_+_18601299 0.97 ENST00000572555.1
ENST00000395902.3
ENST00000449552.2
TRIM16L
tripartite motif containing 16-like
chr17_-_73285293 0.97 ENST00000582778.1
ENST00000581988.1
ENST00000579207.1
ENST00000583332.1
ENST00000416858.2
ENST00000442286.2
ENST00000580151.1
ENST00000580994.1
ENST00000584438.1
ENST00000320362.3
ENST00000580273.1
SLC25A19
solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19
chr15_-_64385981 0.97 ENST00000557835.1
ENST00000380290.3
ENST00000559950.1
FAM96A
family with sequence similarity 96, member A
chr17_+_67410832 0.96 ENST00000590474.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr2_+_219135115 0.96 ENST00000248451.3
ENST00000273077.4
PNKD
paroxysmal nonkinesigenic dyskinesia
chr10_-_69597810 0.94 ENST00000483798.2
DNAJC12
DnaJ (Hsp40) homolog, subfamily C, member 12
chr11_+_60681346 0.94 ENST00000227525.3
TMEM109
transmembrane protein 109
chr9_-_35079911 0.93 ENST00000448890.1
FANCG
Fanconi anemia, complementation group G
chr14_-_81408063 0.93 ENST00000557411.1
CEP128
centrosomal protein 128kDa
chr12_+_53662110 0.93 ENST00000552462.1
ESPL1
extra spindle pole bodies homolog 1 (S. cerevisiae)
chr19_-_59084922 0.93 ENST00000215057.2
ENST00000599369.1
MZF1
myeloid zinc finger 1
chr2_+_136499287 0.93 ENST00000415164.1
UBXN4
UBX domain protein 4
chr19_+_39390587 0.92 ENST00000572515.1
ENST00000392079.3
ENST00000575359.1
ENST00000313582.5
NFKBIB
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
chr19_+_35225060 0.91 ENST00000599244.1
ENST00000392232.3
ZNF181
zinc finger protein 181
chr15_+_40987327 0.91 ENST00000423169.2
ENST00000267868.3
ENST00000557850.1
ENST00000532743.1
ENST00000382643.3
RAD51
RAD51 recombinase
chr2_-_232645977 0.90 ENST00000409772.1
PDE6D
phosphodiesterase 6D, cGMP-specific, rod, delta
chr16_-_4817129 0.90 ENST00000545009.1
ENST00000219478.6
ZNF500
zinc finger protein 500
chr12_-_57146095 0.89 ENST00000550770.1
ENST00000338193.6
PRIM1
primase, DNA, polypeptide 1 (49kDa)
chr1_+_45205478 0.88 ENST00000452259.1
ENST00000372224.4
KIF2C
kinesin family member 2C
chr19_-_46234119 0.88 ENST00000317683.3
FBXO46
F-box protein 46
chr12_+_56660633 0.87 ENST00000308197.5
COQ10A
coenzyme Q10 homolog A (S. cerevisiae)
chr7_-_99869799 0.87 ENST00000436886.2
GATS
GATS, stromal antigen 3 opposite strand
chr19_+_36208877 0.87 ENST00000420124.1
ENST00000222270.7
ENST00000341701.1
KMT2B
Histone-lysine N-methyltransferase 2B
chr19_+_36236491 0.87 ENST00000591949.1
PSENEN
presenilin enhancer gamma secretase subunit
chr17_+_7761013 0.87 ENST00000571846.1
CYB5D1
cytochrome b5 domain containing 1
chr17_+_4634705 0.86 ENST00000575284.1
ENST00000573708.1
ENST00000293777.5
MED11
mediator complex subunit 11
chr9_+_130965677 0.86 ENST00000393594.3
ENST00000486160.1
DNM1
dynamin 1
chr17_+_38444115 0.85 ENST00000580824.1
ENST00000577249.1
CDC6
cell division cycle 6
chr19_+_56653064 0.85 ENST00000593100.1
ZNF444
zinc finger protein 444
chr19_-_2456922 0.85 ENST00000582871.1
ENST00000325327.3
LMNB2
lamin B2
chr2_+_63816295 0.85 ENST00000539945.1
ENST00000544381.1
MDH1
malate dehydrogenase 1, NAD (soluble)
chr5_+_85913721 0.85 ENST00000247655.3
ENST00000509578.1
ENST00000515763.1
COX7C
cytochrome c oxidase subunit VIIc
chr19_+_17530838 0.84 ENST00000528659.1
ENST00000392702.2
ENST00000529939.1
MVB12A
multivesicular body subunit 12A
chr9_-_104160872 0.84 ENST00000539624.1
ENST00000374865.4
MRPL50
mitochondrial ribosomal protein L50
chr1_+_242011468 0.84 ENST00000366548.3
EXO1
exonuclease 1
chr16_-_54963026 0.83 ENST00000560208.1
ENST00000557792.1
CRNDE
colorectal neoplasia differentially expressed (non-protein coding)
chr12_+_53895052 0.83 ENST00000552857.1
TARBP2
TAR (HIV-1) RNA binding protein 2
chr2_+_63816087 0.82 ENST00000409908.1
ENST00000442225.1
ENST00000409476.1
ENST00000436321.1
MDH1
malate dehydrogenase 1, NAD (soluble)
chr16_-_31106211 0.82 ENST00000532364.1
ENST00000529564.1
ENST00000319788.7
ENST00000354895.4
ENST00000394975.2
RP11-196G11.1
VKORC1
Uncharacterized protein
vitamin K epoxide reductase complex, subunit 1
chrX_-_107334790 0.82 ENST00000217958.3
PSMD10
proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
chr7_-_134001663 0.82 ENST00000378509.4
SLC35B4
solute carrier family 35 (UDP-xylose/UDP-N-acetylglucosamine transporter), member B4
chr8_+_145159376 0.82 ENST00000322428.5
MAF1
MAF1 homolog (S. cerevisiae)
chr19_-_55628927 0.81 ENST00000263433.3
ENST00000376393.2
PPP1R12C
protein phosphatase 1, regulatory subunit 12C
chr17_+_76210367 0.80 ENST00000592734.1
ENST00000587746.1
BIRC5
baculoviral IAP repeat containing 5
chr19_-_46389359 0.79 ENST00000302165.3
IRF2BP1
interferon regulatory factor 2 binding protein 1
chr11_+_2421718 0.79 ENST00000380996.5
ENST00000333256.6
ENST00000380992.1
ENST00000437110.1
ENST00000435795.1
TSSC4
tumor suppressing subtransferable candidate 4
chr19_-_59084647 0.78 ENST00000594234.1
ENST00000596039.1
MZF1
myeloid zinc finger 1
chr19_+_12917364 0.78 ENST00000221486.4
RNASEH2A
ribonuclease H2, subunit A
chr22_+_18560743 0.78 ENST00000399744.3
PEX26
peroxisomal biogenesis factor 26
chr7_+_140396465 0.78 ENST00000476279.1
ENST00000247866.4
ENST00000461457.1
ENST00000465506.1
ENST00000204307.5
ENST00000464566.1
NDUFB2
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa
chr8_+_27631903 0.77 ENST00000305188.8
ESCO2
establishment of sister chromatid cohesion N-acetyltransferase 2
chr8_+_110346546 0.77 ENST00000521662.1
ENST00000521688.1
ENST00000520147.1
ENY2
enhancer of yellow 2 homolog (Drosophila)
chrX_-_107334750 0.77 ENST00000340200.5
ENST00000372296.1
ENST00000372295.1
ENST00000361815.5
PSMD10
proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
chr19_+_15218180 0.76 ENST00000342784.2
ENST00000597977.1
ENST00000600440.1
SYDE1
synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
chr22_+_50624323 0.76 ENST00000380909.4
ENST00000303434.4
TRABD
TraB domain containing
chr1_+_45205498 0.75 ENST00000372218.4
KIF2C
kinesin family member 2C
chr19_+_36236514 0.75 ENST00000222266.2
PSENEN
presenilin enhancer gamma secretase subunit
chr2_-_169746878 0.75 ENST00000282074.2
SPC25
SPC25, NDC80 kinetochore complex component
chr8_+_145159415 0.75 ENST00000534585.1
MAF1
MAF1 homolog (S. cerevisiae)
chr22_+_20748456 0.75 ENST00000420626.1
ENST00000356671.5
ZNF74
zinc finger protein 74
chr8_+_27632047 0.75 ENST00000397418.2
ESCO2
establishment of sister chromatid cohesion N-acetyltransferase 2
chr17_-_26662440 0.75 ENST00000578122.1
IFT20
intraflagellar transport 20 homolog (Chlamydomonas)
chr10_+_124913930 0.75 ENST00000368858.5
BUB3
BUB3 mitotic checkpoint protein
chr19_+_4304585 0.74 ENST00000221856.6
FSD1
fibronectin type III and SPRY domain containing 1
chr19_-_50083822 0.73 ENST00000596358.1
NOSIP
nitric oxide synthase interacting protein
chr16_+_58426296 0.73 ENST00000426538.2
ENST00000328514.7
ENST00000318129.5
GINS3
GINS complex subunit 3 (Psf3 homolog)
chr10_-_69597828 0.73 ENST00000339758.7
DNAJC12
DnaJ (Hsp40) homolog, subfamily C, member 12
chr17_-_47492236 0.72 ENST00000434917.2
ENST00000300408.3
ENST00000511832.1
ENST00000419140.2
PHB
prohibitin
chr4_-_2420357 0.72 ENST00000511071.1
ENST00000509171.1
ENST00000290974.2
ZFYVE28
zinc finger, FYVE domain containing 28
chr12_+_56546363 0.72 ENST00000551834.1
ENST00000552568.1
MYL6B
myosin, light chain 6B, alkali, smooth muscle and non-muscle
chr1_+_38158090 0.72 ENST00000373055.1
ENST00000327331.2
CDCA8
cell division cycle associated 8
chr19_+_57946684 0.72 ENST00000334181.4
ENST00000415248.1
ZNF749
zinc finger protein 749
chr8_-_63951730 0.72 ENST00000260118.6
GGH
gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
chr10_+_124913793 0.72 ENST00000368865.4
ENST00000538238.1
ENST00000368859.2
BUB3
BUB3 mitotic checkpoint protein
chr3_-_52188397 0.71 ENST00000474012.1
ENST00000296484.2
POC1A
POC1 centriolar protein A
chr19_+_48949030 0.71 ENST00000253237.5
GRWD1
glutamate-rich WD repeat containing 1
chr19_+_4304632 0.71 ENST00000597590.1
FSD1
fibronectin type III and SPRY domain containing 1
chr19_+_35168567 0.70 ENST00000457781.2
ENST00000505163.1
ENST00000505242.1
ENST00000423823.2
ENST00000507959.1
ENST00000446502.2
ZNF302
zinc finger protein 302
chr17_-_26662464 0.70 ENST00000579419.1
ENST00000585313.1
ENST00000395418.3
ENST00000578985.1
ENST00000577498.1
ENST00000585089.1
ENST00000357896.3
IFT20
intraflagellar transport 20 homolog (Chlamydomonas)
chr9_-_35080013 0.69 ENST00000378643.3
FANCG
Fanconi anemia, complementation group G
chr1_+_242011269 0.69 ENST00000519225.1
EXO1
exonuclease 1
chr7_-_74867509 0.69 ENST00000426327.3
GATSL2
GATS protein-like 2
chr1_+_45205591 0.68 ENST00000455186.1
KIF2C
kinesin family member 2C
chr2_+_241526126 0.68 ENST00000391984.2
ENST00000391982.2
ENST00000404753.3
ENST00000270364.7
ENST00000352879.4
ENST00000354082.4
CAPN10
calpain 10
chr11_-_63933504 0.67 ENST00000255681.6
MACROD1
MACRO domain containing 1
chr14_-_81408093 0.67 ENST00000555265.1
CEP128
centrosomal protein 128kDa
chr17_+_7591747 0.66 ENST00000534050.1
WRAP53
WD repeat containing, antisense to TP53
chr19_-_50083803 0.66 ENST00000391853.3
ENST00000339093.3
NOSIP
nitric oxide synthase interacting protein
chr2_-_133104839 0.66 ENST00000608279.1
RP11-725P16.2
RP11-725P16.2
chr2_+_63816126 0.66 ENST00000454035.1
MDH1
malate dehydrogenase 1, NAD (soluble)
chr12_+_133656995 0.66 ENST00000356456.5
ZNF140
zinc finger protein 140
chr19_+_3762645 0.66 ENST00000330133.4
MRPL54
mitochondrial ribosomal protein L54
chr19_+_58987786 0.65 ENST00000335841.4
ZNF446
zinc finger protein 446
chr12_-_56709786 0.65 ENST00000547423.1
ENST00000548360.1
ENST00000551475.1
RP11-977G19.10
CNPY2
Uncharacterized protein
canopy FGF signaling regulator 2
chr19_-_58892389 0.65 ENST00000427624.2
ENST00000597582.1
ZNF837
zinc finger protein 837
chr1_+_156052354 0.65 ENST00000368301.2
LMNA
lamin A/C
chr17_+_7591639 0.65 ENST00000396463.2
WRAP53
WD repeat containing, antisense to TP53
chr19_+_40697514 0.65 ENST00000253055.3
MAP3K10
mitogen-activated protein kinase kinase kinase 10
chr2_+_63816269 0.65 ENST00000432309.1
MDH1
malate dehydrogenase 1, NAD (soluble)
chr19_+_54619125 0.64 ENST00000445811.1
ENST00000419967.1
ENST00000445124.1
ENST00000447810.1
PRPF31
pre-mRNA processing factor 31
chr19_+_36249044 0.63 ENST00000444637.2
ENST00000396908.4
ENST00000544099.1
C19orf55
chromosome 19 open reading frame 55
chr11_-_66139199 0.63 ENST00000357440.2
SLC29A2
solute carrier family 29 (equilibrative nucleoside transporter), member 2
chr1_-_150241341 0.63 ENST00000369109.3
ENST00000414276.2
ENST00000236017.5
APH1A
APH1A gamma secretase subunit
chr19_+_17530888 0.63 ENST00000528515.1
ENST00000543795.1
MVB12A
multivesicular body subunit 12A
chr2_-_26205550 0.63 ENST00000405914.1
KIF3C
kinesin family member 3C
chr17_+_79981144 0.62 ENST00000306688.3
LRRC45
leucine rich repeat containing 45
chr7_-_150780609 0.62 ENST00000297533.4
TMUB1
transmembrane and ubiquitin-like domain containing 1
chr20_+_30327063 0.62 ENST00000300403.6
ENST00000340513.4
TPX2
TPX2, microtubule-associated
chr19_-_55628700 0.62 ENST00000592993.1
PPP1R12C
protein phosphatase 1, regulatory subunit 12C
chr19_-_28284793 0.61 ENST00000590523.1
LINC00662
long intergenic non-protein coding RNA 662
chr19_+_58258202 0.61 ENST00000431353.1
ZNF776
zinc finger protein 776
chr11_+_57425209 0.61 ENST00000533905.1
ENST00000525602.1
ENST00000302731.4
CLP1
cleavage and polyadenylation factor I subunit 1
chr11_+_74660278 0.60 ENST00000263672.6
ENST00000530257.1
ENST00000526361.1
ENST00000532972.1
SPCS2
signal peptidase complex subunit 2 homolog (S. cerevisiae)
chr19_+_54024251 0.59 ENST00000253144.9
ZNF331
zinc finger protein 331
chr19_-_55677920 0.58 ENST00000524407.2
ENST00000526003.1
ENST00000534170.1
DNAAF3
dynein, axonemal, assembly factor 3
chr2_+_55459495 0.58 ENST00000272317.6
ENST00000449323.1
RPS27A
ribosomal protein S27a
chr19_+_44598492 0.58 ENST00000589680.1
ZNF224
zinc finger protein 224
chr16_-_1525016 0.58 ENST00000262318.8
ENST00000448525.1
CLCN7
chloride channel, voltage-sensitive 7
chr7_+_102389434 0.58 ENST00000409231.3
ENST00000418198.1
FAM185A
family with sequence similarity 185, member A
chr19_+_44669221 0.57 ENST00000590578.1
ENST00000589160.1
ENST00000337433.5
ENST00000586286.1
ENST00000585560.1
ENST00000586914.1
ENST00000588883.1
ENST00000413984.2
ENST00000588742.1
ENST00000300823.6
ENST00000585678.1
ENST00000586203.1
ENST00000590467.1
ENST00000588795.1
ENST00000588127.1
ZNF226
zinc finger protein 226
chr3_-_50329990 0.56 ENST00000417626.2
IFRD2
interferon-related developmental regulator 2
chr8_+_40010989 0.56 ENST00000315792.3
C8orf4
chromosome 8 open reading frame 4
chr17_+_12692774 0.56 ENST00000379672.5
ENST00000340825.3
ARHGAP44
Rho GTPase activating protein 44
chr20_+_62289640 0.56 ENST00000508582.2
ENST00000360203.5
ENST00000356810.4
RTEL1
regulator of telomere elongation helicase 1

Network of associatons between targets according to the STRING database.

First level regulatory network of SIX5_SMARCC2_HCFC1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 4.6 GO:0033499 galactose catabolic process via UDP-galactose(GO:0033499)
0.7 2.2 GO:1903465 vacuolar phosphate transport(GO:0007037) positive regulation of mitotic cell cycle DNA replication(GO:1903465) positive regulation of parathyroid hormone secretion(GO:2000830)
0.7 2.8 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.5 2.0 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.4 1.3 GO:0032203 telomere formation via telomerase(GO:0032203)
0.4 1.7 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.4 2.3 GO:0034227 tRNA thio-modification(GO:0034227)
0.4 2.3 GO:0030423 targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.4 1.8 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.3 2.0 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.3 2.0 GO:0034421 post-translational protein acetylation(GO:0034421)
0.3 1.0 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.3 1.6 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.3 1.2 GO:1904117 response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117)
0.3 0.9 GO:1990426 homologous recombination-dependent replication fork processing(GO:1990426)
0.3 6.2 GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.2 3.0 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.2 0.7 GO:1902299 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.2 1.5 GO:0019348 dolichol metabolic process(GO:0019348)
0.2 1.5 GO:0019075 virus maturation(GO:0019075)
0.2 1.2 GO:0045917 positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
0.2 1.0 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.2 1.0 GO:0072709 cellular response to sorbitol(GO:0072709)
0.2 0.8 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.2 0.6 GO:1902990 mitotic telomere maintenance via semi-conservative replication(GO:1902990)
0.2 3.0 GO:0006108 malate metabolic process(GO:0006108)
0.2 0.7 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.2 0.3 GO:0030001 metal ion transport(GO:0030001)
0.2 0.8 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.2 0.8 GO:0015788 GDP-fucose transport(GO:0015783) UDP-N-acetylglucosamine transport(GO:0015788) purine nucleotide-sugar transport(GO:0036079) UDP-N-acetylglucosamine transmembrane transport(GO:1990569)
0.2 0.8 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.2 0.8 GO:0042350 GDP-L-fucose biosynthetic process(GO:0042350)
0.2 0.5 GO:0070632 spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
0.2 1.1 GO:0035624 receptor transactivation(GO:0035624)
0.1 0.9 GO:0098886 modification of dendritic spine(GO:0098886)
0.1 0.9 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.1 0.4 GO:0006624 vacuolar protein processing(GO:0006624)
0.1 0.4 GO:1902824 positive regulation of late endosome to lysosome transport(GO:1902824)
0.1 1.7 GO:0042373 vitamin K metabolic process(GO:0042373)
0.1 0.4 GO:0000349 generation of catalytic spliceosome for first transesterification step(GO:0000349)
0.1 1.1 GO:0048254 snoRNA localization(GO:0048254)
0.1 0.1 GO:0036090 cleavage furrow ingression(GO:0036090)
0.1 0.8 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.1 0.5 GO:0098968 neurotransmitter receptor transport postsynaptic membrane to endosome(GO:0098968)
0.1 1.3 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.1 2.1 GO:0045008 depyrimidination(GO:0045008)
0.1 0.4 GO:0070510 regulation of histone H4-K20 methylation(GO:0070510) positive regulation of histone H4-K20 methylation(GO:0070512)
0.1 2.5 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.1 1.5 GO:0046322 negative regulation of fatty acid oxidation(GO:0046322)
0.1 2.5 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.1 1.4 GO:0051001 negative regulation of nitric-oxide synthase activity(GO:0051001)
0.1 1.4 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.1 0.9 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 1.1 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.1 0.3 GO:1905053 regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053)
0.1 0.4 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.1 0.5 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.1 0.7 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.1 0.3 GO:1903595 positive regulation of histamine secretion by mast cell(GO:1903595)
0.1 0.3 GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.1 2.6 GO:0007220 Notch receptor processing(GO:0007220)
0.1 0.7 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.1 0.5 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.1 0.8 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.1 1.5 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.1 0.2 GO:0014029 neural crest formation(GO:0014029)
0.1 0.7 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.1 1.3 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.1 1.4 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.1 0.7 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.1 0.2 GO:0001579 medium-chain fatty acid transport(GO:0001579)
0.1 0.3 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.1 0.6 GO:0061511 centriole elongation(GO:0061511)
0.1 0.4 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.1 2.0 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.1 0.8 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.1 0.3 GO:0098838 reduced folate transmembrane transport(GO:0098838)
0.1 0.6 GO:0007256 activation of JNKK activity(GO:0007256)
0.1 0.2 GO:0046168 glycerol-3-phosphate catabolic process(GO:0046168)
0.1 0.4 GO:0018343 protein farnesylation(GO:0018343)
0.1 0.5 GO:1904636 response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
0.1 1.0 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.1 1.1 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.1 0.3 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.1 0.5 GO:0044211 CTP salvage(GO:0044211)
0.1 0.6 GO:0042797 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.1 0.4 GO:0019060 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.1 1.5 GO:0006265 DNA topological change(GO:0006265)
0.1 0.2 GO:0006173 dADP biosynthetic process(GO:0006173)
0.1 0.7 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719)
0.1 0.3 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.1 0.5 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
0.1 0.8 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.1 2.9 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.1 0.3 GO:1903422 negative regulation of synaptic vesicle recycling(GO:1903422)
0.1 1.4 GO:0006743 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.1 0.2 GO:0000412 histone peptidyl-prolyl isomerization(GO:0000412)
0.1 0.6 GO:1900019 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.1 0.5 GO:0089700 protein kinase D signaling(GO:0089700)
0.1 0.5 GO:1904526 regulation of microtubule binding(GO:1904526)
0.1 0.5 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.1 0.3 GO:0009583 detection of light stimulus(GO:0009583)
0.1 0.2 GO:0035668 TRAM-dependent toll-like receptor signaling pathway(GO:0035668) TRAM-dependent toll-like receptor 4 signaling pathway(GO:0035669)
0.1 0.9 GO:0046085 adenosine metabolic process(GO:0046085)
0.1 0.3 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.1 0.8 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.1 0.3 GO:0032383 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.1 0.5 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.1 0.5 GO:0006572 tyrosine catabolic process(GO:0006572)
0.1 0.2 GO:0048200 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.1 2.3 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736)
0.1 0.3 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.0 0.2 GO:1904749 regulation of protein localization to nucleolus(GO:1904749)
0.0 0.4 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.3 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.6 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.6 GO:0072718 response to cisplatin(GO:0072718)
0.0 0.3 GO:0090166 Golgi disassembly(GO:0090166)
0.0 0.2 GO:1903899 positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.0 0.2 GO:0036292 DNA rewinding(GO:0036292)
0.0 1.4 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.0 0.1 GO:0006106 fumarate metabolic process(GO:0006106)
0.0 0.4 GO:0034088 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.0 0.1 GO:0043000 Golgi to plasma membrane CFTR protein transport(GO:0043000)
0.0 0.3 GO:0071169 establishment of protein localization to chromatin(GO:0071169)
0.0 2.1 GO:0018146 keratan sulfate biosynthetic process(GO:0018146)
0.0 0.5 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.0 0.3 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.2 GO:0001189 RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
0.0 0.0 GO:0016078 tRNA catabolic process(GO:0016078)
0.0 0.2 GO:0045007 depurination(GO:0045007)
0.0 1.1 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.1 GO:0032765 positive regulation of mast cell cytokine production(GO:0032765)
0.0 0.2 GO:0002667 lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911)
0.0 0.2 GO:0010820 positive regulation of T cell chemotaxis(GO:0010820)
0.0 0.4 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 0.9 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.0 0.2 GO:0015742 alpha-ketoglutarate transport(GO:0015742)
0.0 0.3 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.0 0.3 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.1 GO:0045062 extrathymic T cell selection(GO:0045062)
0.0 0.1 GO:1903461 Okazaki fragment processing involved in mitotic DNA replication(GO:1903461)
0.0 0.3 GO:0015811 L-cystine transport(GO:0015811)
0.0 0.9 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.1 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0 0.9 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.1 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
0.0 0.5 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.2 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.0 0.7 GO:0006271 DNA strand elongation involved in DNA replication(GO:0006271)
0.0 0.4 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.0 0.3 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 4.0 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.0 1.1 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.9 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.2 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 1.8 GO:0032784 regulation of DNA-templated transcription, elongation(GO:0032784)
0.0 0.3 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 1.4 GO:0071173 mitotic spindle assembly checkpoint(GO:0007094) spindle assembly checkpoint(GO:0071173)
0.0 0.4 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.1 GO:0046356 acetyl-CoA catabolic process(GO:0046356)
0.0 2.4 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 0.2 GO:0010816 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.0 0.1 GO:0098939 dendritic transport of mitochondrion(GO:0098939) anterograde dendritic transport of mitochondrion(GO:0098972)
0.0 0.1 GO:1904204 regulation of skeletal muscle hypertrophy(GO:1904204)
0.0 0.2 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 0.5 GO:0006527 arginine catabolic process(GO:0006527)
0.0 0.3 GO:0048295 positive regulation of isotype switching to IgE isotypes(GO:0048295)
0.0 0.4 GO:0042177 negative regulation of protein catabolic process(GO:0042177)
0.0 0.5 GO:0031297 replication fork processing(GO:0031297)
0.0 0.2 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.0 0.2 GO:2000814 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814)
0.0 0.2 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.0 0.2 GO:0071896 protein localization to adherens junction(GO:0071896)
0.0 0.6 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.1 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.3 GO:0036155 acylglycerol acyl-chain remodeling(GO:0036155)
0.0 0.6 GO:1901642 nucleoside transmembrane transport(GO:1901642)
0.0 0.3 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 1.6 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 0.9 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0 0.1 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.0 0.1 GO:0009149 pyrimidine nucleoside triphosphate catabolic process(GO:0009149) pyrimidine deoxyribonucleoside triphosphate catabolic process(GO:0009213)
0.0 2.9 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0 0.2 GO:0010624 regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626)
0.0 0.3 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.0 0.1 GO:0090156 cellular sphingolipid homeostasis(GO:0090156)
0.0 0.7 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.0 0.5 GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity(GO:0051091)
0.0 0.6 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 0.2 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
0.0 1.0 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 0.1 GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
0.0 0.4 GO:0006751 glutathione catabolic process(GO:0006751)
0.0 0.5 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.2 GO:0009644 response to high light intensity(GO:0009644)
0.0 0.1 GO:0033383 geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384) farnesyl diphosphate biosynthetic process(GO:0045337)
0.0 0.1 GO:0009438 methylglyoxal metabolic process(GO:0009438)
0.0 0.4 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.0 0.1 GO:0032053 ciliary basal body organization(GO:0032053)
0.0 1.6 GO:1902850 microtubule cytoskeleton organization involved in mitosis(GO:1902850)
0.0 0.2 GO:0006293 nucleotide-excision repair, preincision complex stabilization(GO:0006293)
0.0 8.0 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.1 GO:0046022 regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.0 0.3 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.0 0.2 GO:0061042 vascular wound healing(GO:0061042)
0.0 0.2 GO:0002759 regulation of antimicrobial humoral response(GO:0002759)
0.0 1.4 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.1 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.0 0.4 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.0 0.1 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.2 GO:0019896 axonal transport of mitochondrion(GO:0019896)
0.0 0.8 GO:0015991 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991)
0.0 0.2 GO:0042073 intraciliary transport(GO:0042073)
0.0 0.0 GO:1903630 regulation of aminoacyl-tRNA ligase activity(GO:1903630)
0.0 0.6 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.0 0.5 GO:0044458 motile cilium assembly(GO:0044458)
0.0 0.2 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.0 0.1 GO:0030242 pexophagy(GO:0030242)
0.0 0.2 GO:0039530 MDA-5 signaling pathway(GO:0039530)
0.0 0.3 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 1.0 GO:0051225 spindle assembly(GO:0051225)
0.0 1.2 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.0 0.1 GO:0032185 septin cytoskeleton organization(GO:0032185)
0.0 0.2 GO:0006264 mitochondrial DNA replication(GO:0006264)
0.0 0.3 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.1 GO:1903232 melanosome assembly(GO:1903232)
0.0 0.1 GO:1990928 response to amino acid starvation(GO:1990928)
0.0 0.4 GO:0006892 post-Golgi vesicle-mediated transport(GO:0006892)
0.0 0.2 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782) response to insecticide(GO:0017085)
0.0 0.4 GO:0006119 oxidative phosphorylation(GO:0006119)
0.0 0.4 GO:0071305 cellular response to vitamin D(GO:0071305)
0.0 0.2 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.0 0.5 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.0 0.1 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.0 0.4 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.3 GO:0032836 glomerular basement membrane development(GO:0032836)
0.0 0.3 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.3 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.0 0.4 GO:0006362 transcription elongation from RNA polymerase I promoter(GO:0006362)
0.0 0.0 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.0 1.0 GO:0030049 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0 0.1 GO:1900063 regulation of peroxisome organization(GO:1900063)
0.0 0.6 GO:0007052 mitotic spindle organization(GO:0007052)
0.0 0.1 GO:0044375 peroxisome membrane biogenesis(GO:0016557) regulation of peroxisome size(GO:0044375)
0.0 0.0 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.0 0.2 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.4 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 0.3 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.0 GO:0055070 copper ion homeostasis(GO:0055070)
0.0 0.1 GO:0060161 positive regulation of dopamine receptor signaling pathway(GO:0060161)
0.0 0.2 GO:0016075 rRNA catabolic process(GO:0016075)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.5 1.9 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.5 1.5 GO:1990298 mitotic checkpoint complex(GO:0033597) bub1-bub3 complex(GO:1990298)
0.5 1.4 GO:1902636 kinociliary basal body(GO:1902636)
0.4 1.1 GO:0035101 FACT complex(GO:0035101)
0.3 2.6 GO:0032133 chromosome passenger complex(GO:0032133)
0.2 0.7 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.2 2.6 GO:0070765 gamma-secretase complex(GO:0070765)
0.2 3.4 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.2 0.5 GO:0000137 Golgi cis cisterna(GO:0000137)
0.2 0.5 GO:0070762 nuclear pore transmembrane ring(GO:0070762)
0.1 1.5 GO:0005638 lamin filament(GO:0005638)
0.1 0.4 GO:0009346 citrate lyase complex(GO:0009346)
0.1 0.9 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.1 1.6 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 2.4 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 1.4 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.1 0.8 GO:0031262 Ndc80 complex(GO:0031262)
0.1 0.4 GO:1990723 cytoplasmic periphery of the nuclear pore complex(GO:1990723)
0.1 1.7 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.1 0.6 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.1 1.7 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.1 1.4 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1 2.0 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.1 0.4 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.1 0.3 GO:0031933 telomeric heterochromatin(GO:0031933)
0.1 0.9 GO:0005787 signal peptidase complex(GO:0005787)
0.1 0.6 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.1 0.9 GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.1 0.4 GO:0031436 BRCA1-BARD1 complex(GO:0031436)
0.1 0.3 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.1 1.5 GO:0000813 ESCRT I complex(GO:0000813)
0.1 1.1 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.1 0.5 GO:0097165 nuclear stress granule(GO:0097165)
0.1 1.4 GO:0000800 lateral element(GO:0000800)
0.1 1.4 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 0.9 GO:0070652 HAUS complex(GO:0070652)
0.1 0.6 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.1 0.2 GO:0000438 core TFIIH complex portion of holo TFIIH complex(GO:0000438)
0.1 0.5 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.1 0.2 GO:0009368 endopeptidase Clp complex(GO:0009368)
0.1 0.6 GO:0005687 U4 snRNP(GO:0005687)
0.1 0.7 GO:0061689 tricellular tight junction(GO:0061689)
0.1 0.2 GO:0044609 DBIRD complex(GO:0044609)
0.1 0.3 GO:0097058 CRLF-CLCF1 complex(GO:0097058) CNTFR-CLCF1 complex(GO:0097059)
0.1 1.2 GO:0097539 ciliary transition fiber(GO:0097539)
0.1 1.2 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 1.1 GO:0045277 respiratory chain complex IV(GO:0045277)
0.1 0.4 GO:0089701 U2AF(GO:0089701)
0.0 0.2 GO:0044611 nuclear pore inner ring(GO:0044611)
0.0 0.3 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.3 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 1.0 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.4 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.0 1.2 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.6 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 1.4 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.5 GO:0097255 R2TP complex(GO:0097255)
0.0 0.1 GO:0097598 sperm cytoplasmic droplet(GO:0097598)
0.0 0.3 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.0 0.9 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.8 GO:0000124 SAGA complex(GO:0000124)
0.0 2.1 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.3 GO:0005683 U7 snRNP(GO:0005683)
0.0 0.6 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 2.9 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.3 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.0 0.2 GO:0045257 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.5 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 1.1 GO:0071565 nBAF complex(GO:0071565)
0.0 0.3 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.1 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.0 0.4 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 2.2 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.2 GO:0031302 intrinsic component of endosome membrane(GO:0031302)
0.0 0.3 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 0.3 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.2 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 2.1 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.1 GO:0071817 MMXD complex(GO:0071817)
0.0 0.1 GO:0060091 kinocilium(GO:0060091)
0.0 0.3 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.2 GO:0036021 endolysosome lumen(GO:0036021)
0.0 0.2 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.6 GO:0043203 axon hillock(GO:0043203)
0.0 1.0 GO:0072686 mitotic spindle(GO:0072686)
0.0 1.1 GO:0051233 spindle midzone(GO:0051233)
0.0 3.3 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 2.5 GO:0070469 respiratory chain(GO:0070469)
0.0 0.4 GO:0060077 inhibitory synapse(GO:0060077)
0.0 1.0 GO:0097542 ciliary tip(GO:0097542)
0.0 0.2 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.0 0.7 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.5 GO:0000974 Prp19 complex(GO:0000974)
0.0 0.2 GO:0061617 MICOS complex(GO:0061617)
0.0 0.3 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 1.5 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.1 GO:0031905 early endosome lumen(GO:0031905)
0.0 0.1 GO:0035339 SPOTS complex(GO:0035339)
0.0 0.2 GO:0034464 BBSome(GO:0034464)
0.0 0.1 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
0.0 3.5 GO:0000922 spindle pole(GO:0000922)
0.0 0.1 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 1.5 GO:0005844 polysome(GO:0005844)
0.0 0.3 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.4 GO:0035102 PRC1 complex(GO:0035102)
0.0 1.6 GO:0031526 brush border membrane(GO:0031526)
0.0 0.2 GO:0072487 MSL complex(GO:0072487)
0.0 1.0 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.9 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.5 GO:0036064 ciliary basal body(GO:0036064)
0.0 0.1 GO:0034709 methylosome(GO:0034709)
0.0 0.4 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.3 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.3 GO:0031982 vesicle(GO:0031982)
0.0 0.0 GO:0008623 CHRAC(GO:0008623)
0.0 1.3 GO:0055037 recycling endosome(GO:0055037)
0.0 0.2 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.1 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.0 GO:0070931 Golgi-associated vesicle lumen(GO:0070931)
0.0 0.1 GO:0070938 contractile ring(GO:0070938)
0.0 0.0 GO:0031313 extrinsic component of endosome membrane(GO:0031313)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.5 GO:0051908 double-stranded DNA 5'-3' exodeoxyribonuclease activity(GO:0051908)
0.7 3.0 GO:0047860 diiodophenylpyruvate reductase activity(GO:0047860)
0.7 2.1 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.7 2.0 GO:0000994 RNA polymerase III core binding(GO:0000994)
0.5 1.9 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.4 1.3 GO:0004608 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.3 1.7 GO:0016900 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.3 1.6 GO:0000702 oxidized base lesion DNA N-glycosylase activity(GO:0000702)
0.3 1.0 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.3 1.4 GO:0002046 opsin binding(GO:0002046)
0.3 0.6 GO:0005112 Notch binding(GO:0005112)
0.3 0.8 GO:0050333 thiamin-triphosphatase activity(GO:0050333)
0.3 0.8 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.3 2.0 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.2 0.9 GO:0003896 DNA primase activity(GO:0003896)
0.2 2.6 GO:0097322 7SK snRNA binding(GO:0097322)
0.2 4.6 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.2 2.3 GO:0019237 centromeric DNA binding(GO:0019237)
0.2 1.2 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.2 1.0 GO:0015234 thiamine transmembrane transporter activity(GO:0015234)
0.2 2.2 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.2 0.9 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.2 1.3 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.2 0.8 GO:0005462 GDP-fucose transmembrane transporter activity(GO:0005457) UDP-N-acetylglucosamine transmembrane transporter activity(GO:0005462) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
0.2 0.6 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.2 1.7 GO:0070883 pre-miRNA binding(GO:0070883)
0.2 1.7 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.2 0.6 GO:0051733 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.2 1.1 GO:0005047 signal recognition particle binding(GO:0005047)
0.2 0.6 GO:0097363 protein O-GlcNAc transferase activity(GO:0097363)
0.1 0.4 GO:0003878 ATP citrate synthase activity(GO:0003878)
0.1 0.6 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.1 0.4 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.1 0.3 GO:0004019 adenylosuccinate synthase activity(GO:0004019)
0.1 0.3 GO:0033961 cis-stilbene-oxide hydrolase activity(GO:0033961)
0.1 0.4 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.1 0.6 GO:0043262 adenosine-diphosphatase activity(GO:0043262)
0.1 0.5 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
0.1 1.0 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.1 0.4 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 0.7 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
0.1 1.8 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1 0.3 GO:0071209 U7 snRNA binding(GO:0071209)
0.1 2.0 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 0.5 GO:0032089 NACHT domain binding(GO:0032089)
0.1 0.3 GO:0031493 nucleosomal histone binding(GO:0031493)
0.1 0.8 GO:0070990 snRNP binding(GO:0070990)
0.1 0.3 GO:0008518 reduced folate carrier activity(GO:0008518)
0.1 0.2 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.1 1.0 GO:0032027 myosin light chain binding(GO:0032027)
0.1 1.1 GO:0043142 single-stranded DNA-dependent ATPase activity(GO:0043142)
0.1 0.6 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.1 0.5 GO:0016403 dimethylargininase activity(GO:0016403)
0.1 0.3 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.1 0.9 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.1 0.2 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.1 0.5 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.1 0.4 GO:0043532 angiostatin binding(GO:0043532)
0.1 0.2 GO:0097003 adipokinetic hormone receptor activity(GO:0097003)
0.1 0.3 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.1 0.7 GO:0000182 rDNA binding(GO:0000182)
0.1 7.8 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.1 1.2 GO:0001054 RNA polymerase I activity(GO:0001054)
0.1 0.3 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.1 0.2 GO:0047708 biotinidase activity(GO:0047708)
0.1 0.5 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.1 0.2 GO:0050135 NAD(P)+ nucleosidase activity(GO:0050135)
0.1 0.1 GO:0030272 5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
0.1 0.2 GO:0032406 MutLbeta complex binding(GO:0032406) MutSbeta complex binding(GO:0032408)
0.1 0.3 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.0 1.9 GO:0070064 proline-rich region binding(GO:0070064)
0.0 2.2 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 1.4 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.3 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0 5.3 GO:0002039 p53 binding(GO:0002039)
0.0 0.4 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.2 GO:0052642 lysophosphatidic acid phosphatase activity(GO:0052642)
0.0 0.9 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.5 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.8 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.2 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.2 GO:0000104 succinate dehydrogenase activity(GO:0000104)
0.0 0.4 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.2 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.0 1.2 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.1 GO:0019948 SUMO activating enzyme activity(GO:0019948)
0.0 0.9 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.8 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.3 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 1.1 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.2 GO:0015140 malate transmembrane transporter activity(GO:0015140)
0.0 0.3 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.0 0.1 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.0 0.2 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.0 0.1 GO:0070546 L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.0 1.0 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 1.1 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.3 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0 0.1 GO:0004803 transposase activity(GO:0004803)
0.0 0.1 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.1 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.8 GO:0008242 omega peptidase activity(GO:0008242)
0.0 0.1 GO:0016679 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 1.1 GO:0070034 telomerase RNA binding(GO:0070034)
0.0 1.0 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.1 GO:0035651 AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651)
0.0 0.5 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.8 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.2 GO:0008732 glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.0 0.5 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.3 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.3 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.2 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.1 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0 1.4 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.1 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.1 GO:0004337 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.0 0.8 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.1 GO:0050733 RS domain binding(GO:0050733)
0.0 0.8 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.6 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 1.9 GO:0003684 damaged DNA binding(GO:0003684)
0.0 1.3 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.3 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.1 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.0 0.8 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 1.0 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.6 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.6 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 1.8 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.3 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.0 GO:1990698 palmitoleoyltransferase activity(GO:1990698)
0.0 0.1 GO:0032552 deoxyribonucleotide binding(GO:0032552)
0.0 0.7 GO:0005123 death receptor binding(GO:0005123)
0.0 0.3 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.0 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.0 0.2 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0 0.2 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.2 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.3 GO:0000150 recombinase activity(GO:0000150)
0.0 0.1 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.0 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.0 0.2 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.9 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.4 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.2 GO:0003678 DNA helicase activity(GO:0003678)
0.0 0.4 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.0 0.2 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 0.1 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.3 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.4 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.1 GO:0015254 glycerol channel activity(GO:0015254)
0.0 0.4 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.5 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.2 GO:0005537 mannose binding(GO:0005537)
0.0 0.7 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.3 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 0.2 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.5 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.8 GO:0019843 rRNA binding(GO:0019843)
0.0 0.3 GO:0048027 mRNA 5'-UTR binding(GO:0048027)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 6.1 PID AURORA B PATHWAY Aurora B signaling
0.1 2.6 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.1 3.6 PID AURORA A PATHWAY Aurora A signaling
0.0 1.0 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 3.0 ST GAQ PATHWAY G alpha q Pathway
0.0 2.1 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 2.5 PID BARD1 PATHWAY BARD1 signaling events
0.0 2.2 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 1.4 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.3 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.6 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 1.8 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.5 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 1.0 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.4 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.6 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.5 PID ATR PATHWAY ATR signaling pathway
0.0 0.4 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 1.2 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.2 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.3 PID EPHA FWDPATHWAY EPHA forward signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.4 REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS Genes involved in NRIF signals cell death from the nucleus
0.1 2.2 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.1 2.1 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.1 1.0 REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND Genes involved in Processive synthesis on the lagging strand
0.1 2.0 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1 4.5 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 3.3 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.1 1.8 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 1.8 REACTOME RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the multiple-nucleotide patch replacement pathway
0.1 12.1 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 1.9 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.1 2.0 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.1 1.3 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 1.3 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.1 1.8 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.1 2.2 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 3.5 REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.0 0.9 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.6 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 3.2 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 1.3 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.9 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 1.4 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 1.4 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 1.1 REACTOME KINESINS Genes involved in Kinesins
0.0 0.9 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.4 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 1.0 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.6 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 1.7 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.6 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0 0.3 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 1.5 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.8 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.2 REACTOME FORMATION OF THE HIV1 EARLY ELONGATION COMPLEX Genes involved in Formation of the HIV-1 Early Elongation Complex
0.0 0.3 REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21 Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.0 0.3 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 1.7 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 1.4 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.2 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.4 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 0.7 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 1.1 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.3 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.2 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.4 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 1.8 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 1.0 REACTOME TRIGLYCERIDE BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.0 0.4 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.9 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.7 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.3 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.4 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.2 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.4 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.2 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon