Project

SARS-CoV-2 Analysis Results (GEO series: GSE147507)

Navigation
Downloads

Results for SIX6

Z-value: 0.38

Motif logo

Transcription factors associated with SIX6

Gene Symbol Gene ID Gene Info
ENSG00000184302.6 SIX homeobox 6

Activity profile of SIX6 motif

Sorted Z-values of SIX6 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_151531859 1.14 ENST00000488869.1
arylacetamide deacetylase
chr3_+_151531810 0.68 ENST00000232892.7
arylacetamide deacetylase
chr10_+_91061712 0.66 ENST00000371826.3
interferon-induced protein with tetratricopeptide repeats 2
chr12_-_121477039 0.66 ENST00000257570.5
2'-5'-oligoadenylate synthetase-like
chr6_+_37012607 0.66 ENST00000423336.1
cytochrome c oxidase subunit VIa polypeptide 1 pseudogene 2
chr4_-_155511887 0.59 ENST00000302053.3
ENST00000403106.3
fibrinogen alpha chain
chr12_-_121476959 0.57 ENST00000339275.5
2'-5'-oligoadenylate synthetase-like
chr16_+_22524844 0.36 ENST00000538606.1
ENST00000424340.1
ENST00000517539.1
ENST00000528249.1
nuclear pore complex interacting protein family, member B5
chr16_-_29517141 0.33 ENST00000550665.1
Uncharacterized protein
chr12_-_121476750 0.33 ENST00000543677.1
2'-5'-oligoadenylate synthetase-like
chr1_+_212738676 0.32 ENST00000366981.4
ENST00000366987.2
activating transcription factor 3
chr6_+_71104588 0.32 ENST00000418403.1
RP11-462G2.1
chr4_-_184241927 0.31 ENST00000323319.5
claudin 22
chr16_-_21436459 0.31 ENST00000448012.2
ENST00000504841.2
ENST00000419180.2
nuclear pore complex interacting protein family, member B3
chr16_-_21868978 0.28 ENST00000357370.5
ENST00000451409.1
ENST00000341400.7
ENST00000518761.4
nuclear pore complex interacting protein family, member B4
chr19_-_16008880 0.27 ENST00000011989.7
ENST00000221700.6
cytochrome P450, family 4, subfamily F, polypeptide 2
chr16_-_21868739 0.26 ENST00000415645.2
nuclear pore complex interacting protein family, member B4
chr14_+_21152259 0.24 ENST00000555835.1
ENST00000336811.6
ribonuclease, RNase A family, 4
angiogenin, ribonuclease, RNase A family, 5
chr1_-_65468148 0.23 ENST00000415842.1
RP11-182I10.3
chr11_-_104916034 0.22 ENST00000528513.1
ENST00000375706.2
ENST00000375704.3
caspase recruitment domain family, member 16
chr16_+_28648975 0.22 ENST00000529716.1
nuclear pore complex interacting protein family, member B8
chr16_+_22524379 0.20 ENST00000536620.1
nuclear pore complex interacting protein family, member B5
chr20_-_4990931 0.20 ENST00000379333.1
solute carrier family 23 (ascorbic acid transporter), member 2
chr19_-_44031375 0.20 ENST00000292147.2
ethylmalonic encephalopathy 1
chr4_-_6694189 0.19 ENST00000596858.1
Uncharacterized protein
chrX_-_53350522 0.19 ENST00000396435.3
ENST00000375368.5
IQ motif and Sec7 domain 2
chr10_+_52094298 0.16 ENST00000595931.1
HCG1745369; PRO3073; Uncharacterized protein
chr2_+_85822857 0.16 ENST00000306368.4
ENST00000414390.1
ENST00000456023.1
ring finger protein 181
chr4_-_71532339 0.16 ENST00000254801.4
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr1_+_234509186 0.16 ENST00000366615.4
cytochrome c oxidase assembly factor 6 homolog (S. cerevisiae)
chr1_-_161015752 0.15 ENST00000435396.1
ENST00000368021.3
upstream transcription factor 1
chrX_-_99665262 0.15 ENST00000373034.4
ENST00000255531.7
protocadherin 19
chr4_-_71532601 0.13 ENST00000510614.1
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr15_-_80263506 0.13 ENST00000335661.6
BCL2-related protein A1
chr3_+_8543561 0.13 ENST00000397386.3
LIM and cysteine-rich domains 1
chr12_-_11091862 0.12 ENST00000537503.1
taste receptor, type 2, member 14
chr8_+_67104323 0.12 ENST00000518412.1
ENST00000518035.1
ENST00000517725.1
long intergenic non-protein coding RNA 967
chr4_+_189321881 0.12 ENST00000512839.1
ENST00000513313.1
long intergenic non-protein coding RNA 1060
chr2_-_239140011 0.11 ENST00000409376.1
ENST00000409070.1
ENST00000409942.1
Protein LOC151174
chr4_-_71532668 0.11 ENST00000510437.1
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr6_+_127898312 0.11 ENST00000329722.7
chromosome 6 open reading frame 58
chr11_-_104972158 0.11 ENST00000598974.1
ENST00000593315.1
ENST00000594519.1
ENST00000415981.2
ENST00000525374.1
ENST00000375707.1
caspase 1, apoptosis-related cysteine peptidase
caspase recruitment domain family, member 16
caspase recruitment domain family, member 17
chr9_-_23821842 0.10 ENST00000544538.1
ELAV like neuron-specific RNA binding protein 2
chr19_+_46000479 0.10 ENST00000456399.2
protein phosphatase, Mg2+/Mn2+ dependent, 1N (putative)
chr3_-_107596910 0.10 ENST00000464359.2
ENST00000464823.1
ENST00000466155.1
ENST00000473528.2
ENST00000608306.1
ENST00000488852.1
ENST00000608137.1
ENST00000608307.1
ENST00000609429.1
ENST00000601385.1
ENST00000475362.1
ENST00000600240.1
ENST00000600749.1
long intergenic non-protein coding RNA 635
chr18_+_42260059 0.10 ENST00000426838.4
SET binding protein 1
chr5_-_177207634 0.10 ENST00000513554.1
ENST00000440605.3
family with sequence similarity 153, member A
chr8_+_84824920 0.09 ENST00000523678.1
RP11-120I21.2
chr2_+_210636697 0.09 ENST00000439458.1
ENST00000272845.6
unc-80 homolog (C. elegans)
chr2_-_58468437 0.09 ENST00000403676.1
ENST00000427708.2
ENST00000403295.3
ENST00000446381.1
ENST00000417361.1
ENST00000233741.4
ENST00000402135.3
ENST00000540646.1
ENST00000449070.1
Fanconi anemia, complementation group L
chr8_+_12809531 0.09 ENST00000532376.2
KIAA1456
chr6_+_146348782 0.09 ENST00000361719.2
ENST00000392299.2
glutamate receptor, metabotropic 1
chr7_+_117251671 0.09 ENST00000468795.1
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
chr1_+_234509413 0.09 ENST00000366613.1
ENST00000366612.1
cytochrome c oxidase assembly factor 6 homolog (S. cerevisiae)
chr5_+_175490540 0.09 ENST00000515817.1
family with sequence similarity 153, member B
chr21_+_22519416 0.09 ENST00000535285.1
neural cell adhesion molecule 2
chr7_-_123198284 0.08 ENST00000355749.2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
chr1_+_112016414 0.08 ENST00000343534.5
ENST00000369718.3
chromosome 1 open reading frame 162
chr13_-_46679144 0.08 ENST00000181383.4
carboxypeptidase B2 (plasma)
chr19_-_53426700 0.08 ENST00000596623.1
zinc finger protein 888
chr14_-_46185155 0.08 ENST00000555442.1
RP11-369C8.1
chr2_+_27760247 0.08 ENST00000447166.1
Uncharacterized protein
chr13_-_62001982 0.08 ENST00000409186.1
protocadherin 20
chr18_+_55018044 0.08 ENST00000324000.3
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chr17_-_42327236 0.07 ENST00000399246.2
AC003102.1
chr3_+_141457030 0.07 ENST00000273480.3
ring finger protein 7
chr2_+_177134134 0.07 ENST00000249442.6
ENST00000392529.2
ENST00000443241.1
metaxin 2
chr1_-_150669604 0.07 ENST00000427665.1
ENST00000540514.1
golgi phosphoprotein 3-like
chr12_-_78934441 0.07 ENST00000546865.1
ENST00000547089.1
RP11-171L9.1
chr6_+_146348810 0.07 ENST00000492807.2
glutamate receptor, metabotropic 1
chr2_-_77749387 0.07 ENST00000409884.1
leucine rich repeat transmembrane neuronal 4
chr1_-_67142710 0.07 ENST00000502413.2
Uncharacterized protein
chr3_+_259218 0.06 ENST00000449294.2
cell adhesion molecule L1-like
chr13_-_20080080 0.06 ENST00000400103.2
transmembrane phosphoinositide 3-phosphatase and tensin homolog 2
chr3_-_196242233 0.06 ENST00000397537.2
single-pass membrane protein with coiled-coil domains 1
chr2_-_77749474 0.06 ENST00000409093.1
ENST00000409088.3
leucine rich repeat transmembrane neuronal 4
chr6_-_6711235 0.06 ENST00000432823.2
RP1-80N2.2
chrX_+_8433376 0.06 ENST00000440654.2
ENST00000381029.4
variable charge, X-linked 3B
chr22_-_17302589 0.06 ENST00000331428.5
XK, Kell blood group complex subunit-related family, member 3
chr7_+_107332334 0.06 ENST00000541474.1
ENST00000544569.1
solute carrier family 26 (anion exchanger), member 4
chr22_-_19137796 0.06 ENST00000086933.2
goosecoid homeobox 2
chr1_+_86934526 0.06 ENST00000394711.1
chloride channel accessory 1
chr2_-_228497888 0.06 ENST00000264387.4
ENST00000409066.1
chromosome 2 open reading frame 83
chr1_-_65468108 0.06 ENST00000436350.2
RP11-182I10.3
chr12_-_14849470 0.05 ENST00000261170.3
guanylate cyclase 2C (heat stable enterotoxin receptor)
chr9_-_100684845 0.05 ENST00000375119.3
chromosome 9 open reading frame 156
chr11_+_122709200 0.05 ENST00000227348.4
cytotoxic and regulatory T cell molecule
chr2_-_100939195 0.05 ENST00000393437.3
LON peptidase N-terminal domain and ring finger 2
chrX_+_64708615 0.05 ENST00000338957.4
ENST00000423889.3
zinc finger CCCH-type containing 12B
chr4_-_42154895 0.05 ENST00000502486.1
ENST00000504360.1
BEN domain containing 4
chrY_+_16168097 0.05 ENST00000250823.4
variable charge, Y-linked 1B
chr10_-_61720640 0.05 ENST00000521074.1
ENST00000444900.1
chromosome 10 open reading frame 40
chrX_-_18238999 0.05 ENST00000380033.4
ENST00000380030.3
BEN domain containing 2
chr2_-_77749336 0.05 ENST00000409282.1
leucine rich repeat transmembrane neuronal 4
chr10_+_81891416 0.04 ENST00000372270.2
placenta-specific 9
chr15_+_69857515 0.04 ENST00000559477.1
RP11-279F6.1
chrY_-_16098393 0.04 ENST00000250825.4
variable charge, Y-linked
chr5_+_136070614 0.04 ENST00000502421.1
CTB-1I21.1
chr6_-_26018007 0.04 ENST00000244573.3
histone cluster 1, H1a
chr7_-_92855762 0.04 ENST00000453812.2
ENST00000394468.2
HEPACAM family member 2
chr8_+_24241789 0.04 ENST00000256412.4
ENST00000538205.1
ADAM-like, decysin 1
chr12_-_10601963 0.04 ENST00000543893.1
killer cell lectin-like receptor subfamily C, member 1
chr2_-_197457335 0.04 ENST00000260983.3
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
chr4_-_13546632 0.04 ENST00000382438.5
NK3 homeobox 2
chr7_-_141957847 0.04 ENST00000552471.1
ENST00000547058.2
protease, serine, 58
chr4_-_139051839 0.04 ENST00000514600.1
ENST00000513895.1
ENST00000512536.1
long intergenic non-protein coding RNA 616
chr2_+_62132800 0.04 ENST00000538736.1
copper metabolism (Murr1) domain containing 1
chr17_-_67224812 0.04 ENST00000423818.2
ATP-binding cassette, sub-family A (ABC1), member 10
chr21_-_19775973 0.04 ENST00000284885.3
transmembrane protease, serine 15
chr21_-_43735628 0.04 ENST00000291525.10
ENST00000518498.1
trefoil factor 3 (intestinal)
chr8_+_1993152 0.04 ENST00000262113.4
myomesin 2
chr18_+_50278430 0.04 ENST00000578080.1
ENST00000582875.1
ENST00000412726.1
deleted in colorectal carcinoma
chr8_+_24241969 0.04 ENST00000522298.1
ADAM-like, decysin 1
chr19_+_31658405 0.04 ENST00000589511.1
CTC-439O9.3
chr16_+_19467772 0.03 ENST00000219821.5
ENST00000561503.1
ENST00000564959.1
transmembrane channel-like 5
chr3_+_125694347 0.03 ENST00000505382.1
ENST00000511082.1
rhophilin associated tail protein 1B
chr5_+_40909354 0.03 ENST00000313164.9
complement component 7
chr1_-_20446020 0.03 ENST00000375105.3
phospholipase A2, group IID
chr3_+_40141502 0.03 ENST00000539167.1
myosin VIIA and Rab interacting protein
chr15_+_58430567 0.03 ENST00000536493.1
aquaporin 9
chr7_+_6121296 0.03 ENST00000428901.1
AC004895.4
chr8_-_124553437 0.03 ENST00000517956.1
ENST00000443022.2
F-box protein 32
chr11_+_124789146 0.03 ENST00000408930.5
hepatocellular carcinoma, down-regulated 1
chr15_+_58430368 0.03 ENST00000558772.1
ENST00000219919.4
aquaporin 9
chr4_+_88532028 0.03 ENST00000282478.7
dentin sialophosphoprotein
chr16_+_72090053 0.03 ENST00000576168.2
ENST00000567185.3
ENST00000567612.2
haptoglobin
chr8_+_1993173 0.03 ENST00000523438.1
myomesin 2
chr17_-_67057114 0.03 ENST00000370732.2
ATP-binding cassette, sub-family A (ABC1), member 9
chr18_+_74240610 0.03 ENST00000578092.1
ENST00000578613.1
ENST00000583578.1
long intergenic non-protein coding RNA 908
chr16_-_87350970 0.02 ENST00000567970.1
chromosome 16 open reading frame 95
chr5_+_171621176 0.02 ENST00000398186.4
EF-hand calcium binding domain 9
chr21_-_43735446 0.02 ENST00000398431.2
trefoil factor 3 (intestinal)
chr9_-_7800067 0.02 ENST00000358227.4
transmembrane protein 261
chr17_-_67057047 0.02 ENST00000495634.1
ENST00000453985.2
ENST00000585714.1
ATP-binding cassette, sub-family A (ABC1), member 9
chr22_+_18043133 0.02 ENST00000327451.6
ENST00000399813.1
solute carrier family 25 (glutamate carrier), member 18
chr1_+_63063152 0.02 ENST00000371129.3
angiopoietin-like 3
chr2_-_238305397 0.02 ENST00000409809.1
collagen, type VI, alpha 3
chr2_+_62132781 0.02 ENST00000311832.5
copper metabolism (Murr1) domain containing 1
chr11_-_120330047 0.02 ENST00000595283.1
Uncharacterized protein
chr20_+_54987305 0.02 ENST00000371336.3
ENST00000434344.1
Cas scaffolding protein family member 4
chr16_+_21689835 0.02 ENST00000286149.4
ENST00000388958.3
otoancorin
chr21_-_19858196 0.02 ENST00000422787.1
transmembrane protease, serine 15
chr2_+_177134201 0.02 ENST00000452865.1
metaxin 2
chr1_-_13673511 0.02 ENST00000344998.3
ENST00000334600.6
PRAME family member 14
chr13_-_46679185 0.02 ENST00000439329.3
carboxypeptidase B2 (plasma)
chr17_-_5342380 0.02 ENST00000225698.4
complement component 1, q subcomponent binding protein
chr9_-_67786624 0.02 ENST00000455764.2
family with sequence similarity 27, member E3
chr12_-_87232644 0.02 ENST00000549405.2
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr1_+_21880560 0.02 ENST00000425315.2
alkaline phosphatase, liver/bone/kidney
chr9_-_100707116 0.02 ENST00000259456.3
hemogen
chrX_+_38660704 0.01 ENST00000378474.3
MID1 interacting protein 1
chr16_+_66410244 0.01 ENST00000562048.1
ENST00000568155.2
cadherin 5, type 2 (vascular endothelium)
chr8_+_67405438 0.01 ENST00000305454.3
chromosome 8 open reading frame 46
chr4_+_57396766 0.01 ENST00000512175.2
theg spermatid protein-like
chr6_-_26285737 0.01 ENST00000377727.1
ENST00000289352.1
histone cluster 1, H4h
chr4_-_186682716 0.01 ENST00000445343.1
sorbin and SH3 domain containing 2
chr3_-_9994021 0.01 ENST00000411976.2
ENST00000412055.1
proline-rich transmembrane protein 3
chr10_+_45495898 0.01 ENST00000298299.3
zinc finger protein 22
chr5_-_117897751 0.01 ENST00000515704.1
ENST00000506769.1
CTD-2281M20.1
chr1_-_161193349 0.01 ENST00000469730.2
ENST00000463273.1
ENST00000464492.1
ENST00000367990.3
ENST00000470459.2
ENST00000468465.1
ENST00000463812.1
apolipoprotein A-II
chr14_+_83108955 0.01 ENST00000555798.1
ENST00000553760.1
ENST00000555150.1
ENST00000556970.1
RP11-406A9.2
chr11_-_102496063 0.00 ENST00000260228.2
matrix metallopeptidase 20
chr2_-_62081148 0.00 ENST00000404929.1
family with sequence similarity 161, member A
chr8_-_128231299 0.00 ENST00000500112.1
colon cancer associated transcript 1 (non-protein coding)
chr1_-_161015663 0.00 ENST00000534633.1
upstream transcription factor 1
chr2_+_181988560 0.00 ENST00000424170.1
ENST00000435411.1
AC104820.2
chr5_-_78281775 0.00 ENST00000396151.3
ENST00000565165.1
arylsulfatase B
chr9_-_14910990 0.00 ENST00000380881.4
ENST00000422223.2
FRAS1 related extracellular matrix 1

Network of associatons between targets according to the STRING database.

First level regulatory network of SIX6

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.8 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.1 0.3 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.1 0.3 GO:0032304 negative regulation of icosanoid secretion(GO:0032304)
0.1 0.2 GO:0015882 L-ascorbic acid transport(GO:0015882) molecular hydrogen transport(GO:0015993) transepithelial L-ascorbic acid transport(GO:0070904)
0.0 0.7 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.0 0.6 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.2 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.3 GO:0071494 cellular response to UV-C(GO:0071494)
0.0 0.2 GO:0070221 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.0 0.1 GO:0003330 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.0 0.1 GO:1902161 positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)
0.0 0.2 GO:0000432 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432)
0.0 0.2 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.0 1.6 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.1 GO:0071934 thiamine transmembrane transport(GO:0071934)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.0 0.3 GO:0097179 protease inhibitor complex(GO:0097179)
0.0 0.6 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.2 GO:0038038 G-protein coupled receptor homodimeric complex(GO:0038038)
0.0 0.2 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.0 0.1 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
0.0 0.1 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.2 GO:0016589 NURF complex(GO:0016589)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1 0.3 GO:0097258 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.1 0.2 GO:0008520 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.1 1.8 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.2 GO:0004522 ribonuclease A activity(GO:0004522)
0.0 0.3 GO:0089720 caspase binding(GO:0089720)
0.0 0.1 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.0 0.1 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.0 0.2 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.0 0.1 GO:0051800 phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.0 0.1 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.0 0.1 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 2.2 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling