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SARS-CoV-2 Analysis Results (GEO series: GSE147507)
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Results for SOX17
Z-value: 1.09
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Transcription factors associated with SOX17
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| SOX17 | hg19_v2_chr8_+_55370487_55370503 | 0.48 | 3.3e-02 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of SOX17
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.2 | 6.0 | GO:0036343 | psychomotor behavior(GO:0036343) |
| 0.0 | 4.4 | GO:0006614 | SRP-dependent cotranslational protein targeting to membrane(GO:0006614) |
| 0.0 | 4.2 | GO:0060337 | type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357) |
| 0.1 | 3.9 | GO:0090023 | positive regulation of neutrophil chemotaxis(GO:0090023) |
| 0.3 | 3.4 | GO:0034392 | negative regulation of smooth muscle cell apoptotic process(GO:0034392) |
| 0.5 | 2.1 | GO:0009822 | alkaloid catabolic process(GO:0009822) |
| 0.0 | 2.1 | GO:0006198 | cAMP catabolic process(GO:0006198) |
| 0.7 | 2.0 | GO:0051866 | general adaptation syndrome(GO:0051866) |
| 0.5 | 2.0 | GO:0002503 | peptide antigen assembly with MHC class II protein complex(GO:0002503) |
| 0.0 | 1.9 | GO:0007029 | endoplasmic reticulum organization(GO:0007029) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 4.8 | GO:0005577 | fibrinogen complex(GO:0005577) |
| 0.1 | 4.2 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 0.2 | 3.4 | GO:0031089 | platelet dense granule lumen(GO:0031089) |
| 0.0 | 2.7 | GO:0000781 | chromosome, telomeric region(GO:0000781) |
| 0.0 | 1.9 | GO:0000407 | pre-autophagosomal structure(GO:0000407) |
| 0.0 | 1.9 | GO:0099501 | synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501) |
| 0.1 | 1.6 | GO:0072559 | NLRP3 inflammasome complex(GO:0072559) |
| 0.1 | 1.5 | GO:0042613 | MHC class II protein complex(GO:0042613) |
| 0.0 | 1.3 | GO:0009925 | basal plasma membrane(GO:0009925) |
| 0.0 | 1.3 | GO:0035580 | specific granule lumen(GO:0035580) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 4.2 | GO:0019843 | rRNA binding(GO:0019843) |
| 0.3 | 3.9 | GO:0045236 | CXCR chemokine receptor binding(GO:0045236) |
| 0.7 | 3.4 | GO:0060230 | lipoprotein lipase activator activity(GO:0060230) |
| 0.0 | 3.3 | GO:0030374 | ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374) |
| 0.0 | 3.3 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
| 0.0 | 2.1 | GO:0004115 | 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115) |
| 0.1 | 2.0 | GO:0035259 | glucocorticoid receptor binding(GO:0035259) |
| 0.0 | 2.0 | GO:0005178 | integrin binding(GO:0005178) |
| 0.1 | 1.8 | GO:0070330 | aromatase activity(GO:0070330) |
| 0.0 | 1.8 | GO:0030371 | translation repressor activity(GO:0030371) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.9 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.0 | 1.8 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.0 | 1.8 | PID FOXM1 PATHWAY | FOXM1 transcription factor network |
| 0.0 | 1.4 | PID RAC1 REG PATHWAY | Regulation of RAC1 activity |
| 0.0 | 1.4 | PID ERA GENOMIC PATHWAY | Validated nuclear estrogen receptor alpha network |
| 0.0 | 1.0 | ST WNT CA2 CYCLIC GMP PATHWAY | Wnt/Ca2+/cyclic GMP signaling. |
| 0.0 | 0.9 | PID RAS PATHWAY | Regulation of Ras family activation |
| 0.0 | 0.5 | PID CONE PATHWAY | Visual signal transduction: Cones |
| 0.0 | 0.4 | PID ERBB NETWORK PATHWAY | ErbB receptor signaling network |
| 0.0 | 0.3 | PID FCER1 PATHWAY | Fc-epsilon receptor I signaling in mast cells |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 4.2 | REACTOME INTERFERON ALPHA BETA SIGNALING | Genes involved in Interferon alpha/beta signaling |
| 0.0 | 4.0 | REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
| 0.1 | 3.9 | REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
| 0.0 | 3.0 | REACTOME G ALPHA S SIGNALLING EVENTS | Genes involved in G alpha (s) signalling events |
| 0.0 | 2.0 | REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
| 0.1 | 1.9 | REACTOME XENOBIOTICS | Genes involved in Xenobiotics |
| 0.1 | 1.8 | REACTOME G2 M DNA DAMAGE CHECKPOINT | Genes involved in G2/M DNA damage checkpoint |
| 0.0 | 1.8 | REACTOME GLUTATHIONE CONJUGATION | Genes involved in Glutathione conjugation |
| 0.0 | 1.7 | REACTOME MUSCLE CONTRACTION | Genes involved in Muscle contraction |
| 0.0 | 1.1 | REACTOME CHONDROITIN SULFATE BIOSYNTHESIS | Genes involved in Chondroitin sulfate biosynthesis |