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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for SOX18

Z-value: 0.65

Motif logo

Transcription factors associated with SOX18

Gene Symbol Gene ID Gene Info
ENSG00000203883.5 SRY-box transcription factor 18

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SOX18hg19_v2_chr20_-_62680984_62680999-0.058.2e-01Click!

Activity profile of SOX18 motif

Sorted Z-values of SOX18 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_133465228 1.66 ENST00000482271.1
ENST00000264998.3
transferrin
chr11_+_5710919 1.13 ENST00000379965.3
ENST00000425490.1
tripartite motif containing 22
chr17_+_41158742 1.01 ENST00000415816.2
ENST00000438323.2
interferon-induced protein 35
chr11_+_5711010 0.93 ENST00000454828.1
tripartite motif containing 22
chr6_-_32908792 0.79 ENST00000418107.2
major histocompatibility complex, class II, DM beta
chr22_-_38480100 0.75 ENST00000427592.1
solute carrier family 16 (monocarboxylate transporter), member 8
chr15_-_41166414 0.72 ENST00000220507.4
ras homolog family member V
chr1_-_32801825 0.71 ENST00000329421.7
MARCKS-like 1
chr17_-_54893250 0.70 ENST00000397862.2
chromosome 17 open reading frame 67
chr1_+_37947257 0.69 ENST00000471012.1
zinc finger CCCH-type containing 12A
chr2_+_241544834 0.68 ENST00000319838.5
ENST00000403859.1
ENST00000438013.2
G protein-coupled receptor 35
chr12_-_10573149 0.68 ENST00000381904.2
ENST00000381903.2
ENST00000396439.2
killer cell lectin-like receptor subfamily C, member 3
chr7_+_99933730 0.65 ENST00000610247.1
paired immunoglobin-like type 2 receptor beta
chr8_+_40010989 0.63 ENST00000315792.3
chromosome 8 open reading frame 4
chr19_-_42192189 0.62 ENST00000401731.1
ENST00000338196.4
ENST00000006724.3
carcinoembryonic antigen-related cell adhesion molecule 7
chr19_+_41256764 0.61 ENST00000243563.3
ENST00000601253.1
ENST00000597353.1
ENST00000599362.1
small nuclear ribonucleoprotein polypeptide A
chr12_-_8088871 0.60 ENST00000075120.7
solute carrier family 2 (facilitated glucose transporter), member 3
chr8_+_35649365 0.60 ENST00000437887.1
Uncharacterized protein
chr19_-_39805976 0.58 ENST00000248668.4
leucine rich repeat and fibronectin type III domain containing 1
chr22_-_31324215 0.57 ENST00000429468.1
MORC family CW-type zinc finger 2
chr16_+_28770025 0.56 ENST00000435324.2
nuclear pore complex interacting protein family, member B9
chr12_+_104697504 0.55 ENST00000527879.1
EP300 interacting inhibitor of differentiation 3
chr11_+_113258495 0.53 ENST00000303941.3
ankyrin repeat and kinase domain containing 1
chr19_+_36132631 0.52 ENST00000379026.2
ENST00000379023.4
ENST00000402764.2
ENST00000479824.1
ets variant 2
chr3_+_186330712 0.51 ENST00000411641.2
ENST00000273784.5
alpha-2-HS-glycoprotein
chr19_+_41257084 0.51 ENST00000601393.1
small nuclear ribonucleoprotein polypeptide A
chr4_+_109541772 0.49 ENST00000506397.1
ENST00000394668.2
ribosomal protein L34
chr8_-_1922789 0.49 ENST00000521498.1
RP11-439C15.4
chr6_-_33385854 0.49 ENST00000488478.1
cutA divalent cation tolerance homolog (E. coli)
chr6_+_89790490 0.49 ENST00000336032.3
proline-rich nuclear receptor coactivator 1
chr6_-_33385870 0.49 ENST00000488034.1
cutA divalent cation tolerance homolog (E. coli)
chr6_-_33385655 0.49 ENST00000440279.3
ENST00000607266.1
cutA divalent cation tolerance homolog (E. coli)
chr12_+_113344582 0.48 ENST00000202917.5
ENST00000445409.2
ENST00000452357.2
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chrX_-_47004437 0.47 ENST00000276062.8
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa
chr8_+_119294456 0.45 ENST00000366457.2
Uncharacterized protein
chr15_+_75628232 0.45 ENST00000267935.8
ENST00000567195.1
COMM domain containing 4
chrX_+_52920336 0.45 ENST00000452154.2
family with sequence similarity 156, member B
chr11_-_76155618 0.43 ENST00000530759.1
RP11-111M22.3
chr9_-_123812542 0.43 ENST00000223642.1
complement component 5
chr6_-_33385902 0.42 ENST00000374500.5
cutA divalent cation tolerance homolog (E. coli)
chr12_-_70093235 0.41 ENST00000266661.4
bestrophin 3
chr11_-_118966167 0.41 ENST00000530167.1
H2A histone family, member X
chr6_-_33385823 0.41 ENST00000494751.1
ENST00000374496.3
cutA divalent cation tolerance homolog (E. coli)
chr19_+_1249869 0.41 ENST00000591446.2
midnolin
chr2_-_114647327 0.41 ENST00000602760.1
RP11-141B14.1
chr18_+_3447572 0.41 ENST00000548489.2
TGFB-induced factor homeobox 1
chr17_+_6916527 0.39 ENST00000552321.1
ribonuclease, RNase K
chr12_+_70574088 0.39 ENST00000552324.1
RP11-320P7.2
chr12_-_11150474 0.38 ENST00000538986.1
taste receptor, type 2, member 20
chr6_-_134639180 0.37 ENST00000367858.5
serum/glucocorticoid regulated kinase 1
chr4_+_164265035 0.36 ENST00000338566.3
neuropeptide Y receptor Y5
chr11_-_104817919 0.36 ENST00000533252.1
caspase 4, apoptosis-related cysteine peptidase
chr14_+_24458123 0.36 ENST00000545240.1
ENST00000382755.4
dehydrogenase/reductase (SDR family) member 4 like 2
chr17_+_72427477 0.36 ENST00000342648.5
ENST00000481232.1
G protein-coupled receptor, family C, group 5, member C
chr7_-_148725733 0.36 ENST00000286091.4
protein disulfide isomerase family A, member 4
chr20_+_31870927 0.35 ENST00000253354.1
BPI fold containing family B, member 1
chr12_-_10562356 0.35 ENST00000309384.1
killer cell lectin-like receptor subfamily C, member 4
chr12_-_85430024 0.34 ENST00000547836.1
ENST00000532498.2
tetraspanin 19
chr7_-_121944491 0.34 ENST00000331178.4
ENST00000427185.2
ENST00000442488.2
FEZ family zinc finger 1
chr15_+_44084040 0.34 ENST00000249786.4
small EDRK-rich factor 2
chr7_-_33080506 0.32 ENST00000381626.2
ENST00000409467.1
ENST00000449201.1
5'-nucleotidase, cytosolic IIIA
chr12_+_110940111 0.32 ENST00000409778.3
RAD9 homolog B (S. pombe)
chr6_+_89790459 0.32 ENST00000369472.1
proline-rich nuclear receptor coactivator 1
chr2_-_158345462 0.32 ENST00000439355.1
ENST00000540637.1
cytohesin 1 interacting protein
chr6_-_133035185 0.31 ENST00000367928.4
vanin 1
chr6_-_31125850 0.31 ENST00000507751.1
ENST00000448162.2
ENST00000502557.1
ENST00000503420.1
ENST00000507892.1
ENST00000507226.1
ENST00000513222.1
ENST00000503934.1
ENST00000396263.2
ENST00000508683.1
ENST00000428174.1
ENST00000448141.2
ENST00000507829.1
ENST00000455279.2
ENST00000376266.5
coiled-coil alpha-helical rod protein 1
chr19_-_42006539 0.30 ENST00000597702.1
ENST00000588495.1
ENST00000595837.1
ENST00000594315.1
AC011526.1
chr7_+_141408153 0.30 ENST00000397541.2
WEE1 homolog 2 (S. pombe)
chr4_+_26322987 0.29 ENST00000505958.1
recombination signal binding protein for immunoglobulin kappa J region
chr12_+_15475462 0.29 ENST00000543886.1
ENST00000348962.2
protein tyrosine phosphatase, receptor type, O
chr17_+_68071389 0.29 ENST00000283936.1
ENST00000392671.1
potassium inwardly-rectifying channel, subfamily J, member 16
chr8_-_102218292 0.29 ENST00000518336.1
ENST00000520454.1
zinc finger protein 706
chr6_-_26235206 0.29 ENST00000244534.5
histone cluster 1, H1d
chr11_+_123986069 0.28 ENST00000456829.2
ENST00000361352.5
ENST00000449321.1
ENST00000392748.1
ENST00000360334.4
ENST00000392744.4
von Willebrand factor A domain containing 5A
chr15_+_75628394 0.28 ENST00000564815.1
ENST00000338995.6
COMM domain containing 4
chr8_-_123793048 0.28 ENST00000607710.1
RP11-44N11.2
chr15_+_75628419 0.28 ENST00000567377.1
ENST00000562789.1
ENST00000568301.1
COMM domain containing 4
chr1_-_114430169 0.28 ENST00000393316.3
BCL2-like 15
chr5_-_67730240 0.28 ENST00000507733.1
CTC-537E7.3
chr12_-_11002063 0.28 ENST00000544994.1
ENST00000228811.4
ENST00000540107.1
proline rich 4 (lacrimal)
chr17_+_41150290 0.27 ENST00000589037.1
ENST00000253788.5
ribosomal protein L27
chr12_+_96252706 0.27 ENST00000266735.5
ENST00000553192.1
ENST00000552085.1
small nuclear ribonucleoprotein polypeptide F
chr4_+_69962185 0.27 ENST00000305231.7
UDP glucuronosyltransferase 2 family, polypeptide B7
chr4_+_110736659 0.27 ENST00000394631.3
ENST00000226796.6
GAR1 ribonucleoprotein
chr15_-_64385981 0.27 ENST00000557835.1
ENST00000380290.3
ENST00000559950.1
family with sequence similarity 96, member A
chr8_-_27468842 0.26 ENST00000523500.1
clusterin
chr4_+_109541722 0.26 ENST00000394667.3
ENST00000502534.1
ribosomal protein L34
chrX_+_100645812 0.25 ENST00000427805.2
ENST00000553110.3
ENST00000392994.3
ENST00000409338.1
ENST00000409170.3
ribosomal protein L36a
RPL36A-HNRNPH2 readthrough
chr6_-_27880174 0.25 ENST00000303324.2
olfactory receptor, family 2, subfamily B, member 2
chr4_+_109541740 0.25 ENST00000394665.1
ribosomal protein L34
chr1_-_117021430 0.25 ENST00000423907.1
ENST00000434879.1
ENST00000443219.1
RP4-655J12.4
chr17_+_25799008 0.25 ENST00000583370.1
ENST00000398988.3
ENST00000268763.6
kinase suppressor of ras 1
chr16_+_48657337 0.25 ENST00000568150.1
ENST00000564212.1
RP11-42I10.1
chrM_+_8366 0.25 ENST00000361851.1
mitochondrially encoded ATP synthase 8
chr16_+_48657361 0.24 ENST00000565072.1
RP11-42I10.1
chrX_+_37850026 0.24 ENST00000341016.3
chromosome X open reading frame 27
chr1_-_201123586 0.24 ENST00000414605.2
ENST00000367334.5
ENST00000367332.1
transmembrane protein 9
chr17_-_43502987 0.24 ENST00000376922.2
Rho GTPase activating protein 27
chrM_+_8527 0.24 ENST00000361899.2
mitochondrially encoded ATP synthase 6
chr11_-_76155700 0.24 ENST00000572035.1
RP11-111M22.3
chr17_+_68071458 0.24 ENST00000589377.1
potassium inwardly-rectifying channel, subfamily J, member 16
chr5_+_57878859 0.23 ENST00000282878.4
RAB3C, member RAS oncogene family
chr11_+_71276609 0.23 ENST00000398531.1
ENST00000376536.4
keratin associated protein 5-10
chr12_+_8666126 0.23 ENST00000299665.2
C-type lectin domain family 4, member D
chr1_+_161123536 0.23 ENST00000368003.5
ubiquitin-fold modifier conjugating enzyme 1
chr9_-_99064429 0.23 ENST00000375263.3
hydroxysteroid (17-beta) dehydrogenase 3
chr10_-_4285923 0.22 ENST00000418372.1
ENST00000608792.1
long intergenic non-protein coding RNA 702
chr15_+_28624878 0.22 ENST00000450328.2
golgin A8 family, member F
chr2_+_1418154 0.22 ENST00000423320.1
ENST00000382198.1
thyroid peroxidase
chr9_-_99064386 0.22 ENST00000375262.2
hydroxysteroid (17-beta) dehydrogenase 3
chr1_+_172745006 0.22 ENST00000432694.2
RP1-15D23.2
chr12_+_113344755 0.22 ENST00000550883.1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr13_+_32313658 0.22 ENST00000380314.1
ENST00000298386.2
relaxin/insulin-like family peptide receptor 2
chr11_-_89224508 0.21 ENST00000525196.1
NADPH oxidase 4
chr17_-_17184605 0.21 ENST00000268717.5
COP9 signalosome subunit 3
chr12_+_110940005 0.21 ENST00000409246.1
ENST00000392672.4
ENST00000409300.1
ENST00000409425.1
RAD9 homolog B (S. pombe)
chr3_-_122283424 0.21 ENST00000477522.2
ENST00000360356.2
poly (ADP-ribose) polymerase family, member 9
chr10_-_73497581 0.21 ENST00000398786.2
chromosome 10 open reading frame 105
chr3_+_188817891 0.21 ENST00000412373.1
tumor protein p63 regulated 1
chr2_-_158345341 0.21 ENST00000435117.1
cytohesin 1 interacting protein
chr15_-_64386120 0.20 ENST00000300030.3
family with sequence similarity 96, member A
chr12_-_11244912 0.20 ENST00000531678.1
taste receptor, type 2, member 43
chr19_-_7936344 0.20 ENST00000599142.1
Protein FLJ22184
chr11_+_26495447 0.20 ENST00000531568.1
anoctamin 3
chr12_-_56321397 0.20 ENST00000557259.1
ENST00000549939.1
within bgcn homolog (Drosophila)
chr10_+_18429606 0.20 ENST00000324631.7
ENST00000352115.6
ENST00000377328.1
calcium channel, voltage-dependent, beta 2 subunit
chr6_+_123317116 0.20 ENST00000275162.5
clavesin 2
chr1_-_153517473 0.20 ENST00000368715.1
S100 calcium binding protein A4
chr18_+_74240610 0.20 ENST00000578092.1
ENST00000578613.1
ENST00000583578.1
long intergenic non-protein coding RNA 908
chr8_-_21669826 0.20 ENST00000517328.1
GDNF family receptor alpha 2
chr8_+_86999516 0.20 ENST00000521564.1
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2
chr3_+_19189946 0.19 ENST00000328405.2
potassium voltage-gated channel, subfamily H (eag-related), member 8
chr1_-_11918988 0.19 ENST00000376468.3
natriuretic peptide B
chr6_+_25652501 0.18 ENST00000334979.6
secretagogin, EF-hand calcium binding protein
chr9_-_127533519 0.18 ENST00000487099.2
ENST00000344523.4
ENST00000373584.3
nuclear receptor subfamily 6, group A, member 1
chr17_+_6658878 0.18 ENST00000574394.1
XIAP associated factor 1
chr10_-_127505167 0.18 ENST00000368786.1
uroporphyrinogen III synthase
chr17_+_41150479 0.18 ENST00000589913.1
ribosomal protein L27
chr15_+_62359175 0.18 ENST00000355522.5
C2 calcium-dependent domain containing 4A
chr17_-_39041479 0.18 ENST00000167588.3
keratin 20
chr2_-_165811756 0.18 ENST00000409662.1
solute carrier family 38, member 11
chr11_+_327171 0.18 ENST00000534483.1
ENST00000524824.1
ENST00000531076.1
RP11-326C3.12
chr3_-_146262637 0.18 ENST00000472349.1
ENST00000342435.4
phospholipid scramblase 1
chr12_-_27235447 0.17 ENST00000429849.2
chromosome 12 open reading frame 71
chr5_+_99871004 0.17 ENST00000312637.4
family with sequence similarity 174, member A
chr16_-_77468945 0.17 ENST00000282849.5
ADAM metallopeptidase with thrombospondin type 1 motif, 18
chr12_-_11139511 0.17 ENST00000506868.1
taste receptor, type 2, member 50
chr3_+_108541545 0.17 ENST00000295756.6
T cell receptor associated transmembrane adaptor 1
chr19_+_44576296 0.17 ENST00000421176.3
zinc finger protein 284
chr11_-_85397167 0.17 ENST00000316398.3
coiled-coil domain containing 89
chr8_-_86253888 0.17 ENST00000522389.1
ENST00000432364.2
ENST00000517618.1
carbonic anhydrase I
chr7_-_122339162 0.16 ENST00000340112.2
ring finger protein 133
chrX_+_47077632 0.16 ENST00000457458.2
cyclin-dependent kinase 16
chr21_-_15918618 0.16 ENST00000400564.1
ENST00000400566.1
SAM domain, SH3 domain and nuclear localization signals 1
chr1_+_8021713 0.15 ENST00000338639.5
ENST00000493678.1
ENST00000377493.5
parkinson protein 7
chr8_-_27469196 0.15 ENST00000546343.1
ENST00000560566.1
clusterin
chrX_+_119495934 0.15 ENST00000218008.3
ENST00000361319.3
ENST00000539306.1
ATPase, Na+/K+ transporting, beta 4 polypeptide
chr4_-_76944621 0.14 ENST00000306602.1
chemokine (C-X-C motif) ligand 10
chr11_-_89224139 0.14 ENST00000413594.2
NADPH oxidase 4
chrX_+_36254051 0.14 ENST00000378657.4
chromosome X open reading frame 30
chr7_-_45026419 0.14 ENST00000578968.1
ENST00000580528.1
small nucleolar RNA host gene 15 (non-protein coding)
chr15_+_69857515 0.14 ENST00000559477.1
RP11-279F6.1
chr19_+_39971505 0.14 ENST00000544017.1
translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
chr4_+_69962212 0.14 ENST00000508661.1
UDP glucuronosyltransferase 2 family, polypeptide B7
chr11_-_5248294 0.14 ENST00000335295.4
hemoglobin, beta
chr11_-_89224299 0.14 ENST00000343727.5
ENST00000531342.1
ENST00000375979.3
NADPH oxidase 4
chr1_-_201123546 0.14 ENST00000435310.1
ENST00000485839.2
ENST00000367330.1
transmembrane protein 9
chr17_+_56315936 0.13 ENST00000543544.1
lactoperoxidase
chr12_-_56321649 0.13 ENST00000454792.2
ENST00000408946.2
within bgcn homolog (Drosophila)
chr11_-_89224488 0.13 ENST00000534731.1
ENST00000527626.1
NADPH oxidase 4
chr4_+_88529681 0.13 ENST00000399271.1
dentin sialophosphoprotein
chr7_-_93204033 0.13 ENST00000359558.2
ENST00000360249.4
ENST00000426151.1
calcitonin receptor
chr6_+_138725343 0.13 ENST00000607197.1
ENST00000367697.3
heme binding protein 2
chr7_+_35756092 0.13 ENST00000458087.3
AC018647.3
chrX_+_47004599 0.13 ENST00000329236.7
RNA binding motif protein 10
chr3_-_93692781 0.13 ENST00000394236.3
protein S (alpha)
chr4_+_156588115 0.13 ENST00000455639.2
guanylate cyclase 1, soluble, alpha 3
chr19_-_44331332 0.12 ENST00000602179.1
LY6/PLAUR domain containing 5
chr4_+_3443614 0.12 ENST00000382774.3
ENST00000511533.1
HGF activator
chrX_+_47004639 0.12 ENST00000345781.6
RNA binding motif protein 10
chr10_-_105992059 0.12 ENST00000369720.1
ENST00000369719.1
ENST00000357060.3
ENST00000428666.1
ENST00000278064.2
WD repeat domain 96
chr14_-_22938665 0.12 ENST00000535880.2
T cell receptor delta variable 3
chr10_-_135187193 0.12 ENST00000368547.3
enoyl CoA hydratase, short chain, 1, mitochondrial
chr22_+_45714672 0.12 ENST00000424557.1
family with sequence similarity 118, member A
chr16_-_787771 0.12 ENST00000568545.1
nuclear prelamin A recognition factor-like
chr17_-_39123144 0.12 ENST00000355612.2
keratin 39
chr6_-_75953484 0.12 ENST00000472311.2
ENST00000460985.1
ENST00000377978.3
ENST00000509698.1
ENST00000230459.4
ENST00000370089.2
cytochrome c oxidase subunit VIIa polypeptide 2 (liver)
chr1_-_156828810 0.12 ENST00000368195.3
insulin receptor-related receptor
chr16_-_68034470 0.11 ENST00000412757.2
dipeptidase 2
chr11_+_134201911 0.11 ENST00000389881.3
galactosidase, beta 1-like 2
chr11_-_89223883 0.11 ENST00000528341.1
NADPH oxidase 4
chr5_+_127039075 0.11 ENST00000514853.2
CTC-228N24.1
chr9_-_125330838 0.11 ENST00000304865.2
olfactory receptor, family 1, subfamily L, member 8
chr4_+_156588249 0.11 ENST00000393832.3
guanylate cyclase 1, soluble, alpha 3
chrX_-_2847366 0.11 ENST00000381154.1
arylsulfatase D
chr6_-_139613269 0.11 ENST00000358430.3
taxilin beta
chr9_-_130497565 0.11 ENST00000336067.6
ENST00000373281.5
ENST00000373284.5
ENST00000458505.3
torsin family 2, member A
chr5_+_147648393 0.11 ENST00000511106.1
ENST00000398450.4
serine peptidase inhibitor, Kazal type 13 (putative)
chr12_-_772901 0.11 ENST00000305108.4
ninjurin 2
chrX_-_101726732 0.11 ENST00000457521.2
ENST00000412230.2
ENST00000453326.2
nuclear RNA export factor 2B
t-complex 11 family, X-linked 2

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX18

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.7 GO:0097460 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.3 0.8 GO:2001190 positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
0.2 0.7 GO:2000627 regulation of miRNA catabolic process(GO:2000625) positive regulation of miRNA catabolic process(GO:2000627)
0.2 0.5 GO:0060796 regulation of transcription involved in primary germ layer cell fate commitment(GO:0060796)
0.1 0.7 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.1 0.6 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.1 0.3 GO:0035038 female pronucleus assembly(GO:0035038)
0.1 0.3 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.1 0.3 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.1 0.8 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.1 0.4 GO:0014050 negative regulation of glutamate secretion(GO:0014050)
0.1 0.4 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.1 0.4 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.1 0.6 GO:1900019 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.1 0.2 GO:0071418 cellular response to amine stimulus(GO:0071418)
0.1 0.3 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 0.4 GO:0061370 testosterone biosynthetic process(GO:0061370)
0.1 0.8 GO:0015727 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.1 0.4 GO:1902847 regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.0 0.1 GO:1903383 enzyme active site formation(GO:0018307) neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036482) detoxification of mercury ion(GO:0050787) positive regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902958) regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) regulation of dopamine biosynthetic process(GO:1903179) positive regulation of dopamine biosynthetic process(GO:1903181) regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903383) negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903384) negative regulation of ubiquitin-specific protease activity(GO:2000157)
0.0 0.1 GO:0044727 DNA demethylation of male pronucleus(GO:0044727)
0.0 0.2 GO:0052565 response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565)
0.0 0.3 GO:0098912 membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912) positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.4 GO:0034144 negative regulation of toll-like receptor 4 signaling pathway(GO:0034144)
0.0 0.1 GO:0030185 nitric oxide transport(GO:0030185)
0.0 0.4 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0 1.1 GO:1900363 regulation of mRNA polyadenylation(GO:1900363)
0.0 0.2 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.3 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 1.0 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.4 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.1 GO:0071469 cellular response to alkaline pH(GO:0071469)
0.0 0.2 GO:0051480 regulation of cytosolic calcium ion concentration(GO:0051480)
0.0 0.7 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0 2.1 GO:0070206 protein trimerization(GO:0070206)
0.0 0.2 GO:0061590 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.0 0.3 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.0 0.2 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.5 GO:0000076 DNA replication checkpoint(GO:0000076) intra-S DNA damage checkpoint(GO:0031573)
0.0 0.3 GO:0033089 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.0 1.2 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 0.5 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.0 0.1 GO:0003192 mitral valve formation(GO:0003192)
0.0 0.3 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.2 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 0.2 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.1 GO:0060467 negative regulation of fertilization(GO:0060467)
0.0 0.2 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.0 0.4 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 0.2 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 0.2 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659) regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373)
0.0 0.1 GO:0039650 modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
0.0 0.1 GO:0010819 regulation of T cell chemotaxis(GO:0010819)
0.0 0.2 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 1.9 GO:0071357 type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.0 0.1 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.1 GO:0010940 positive regulation of necrotic cell death(GO:0010940)
0.0 0.5 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 1.0 GO:0006968 cellular defense response(GO:0006968)
0.0 0.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 1.7 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.7 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.1 0.7 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1 0.5 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.1 0.5 GO:0030896 checkpoint clamp complex(GO:0030896)
0.1 0.4 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.4 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.0 0.3 GO:0090661 box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.0 0.7 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.8 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.1 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.3 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.0 0.1 GO:0042585 germinal vesicle(GO:0042585)
0.0 0.2 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.4 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.0 2.1 GO:0015030 Cajal body(GO:0015030)
0.0 0.5 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.0 0.1 GO:1903439 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.0 0.1 GO:0070702 inner mucus layer(GO:0070702) outer mucus layer(GO:0070703)
0.0 0.3 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.1 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 0.1 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 0.2 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.1 GO:0097361 CIA complex(GO:0097361)
0.0 0.1 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 1.6 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.2 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.2 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.2 1.1 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.1 0.6 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.1 0.4 GO:0001601 peptide YY receptor activity(GO:0001601)
0.1 0.3 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.1 0.4 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.1 0.2 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.1 0.8 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 0.7 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1 0.7 GO:0019826 oxygen sensor activity(GO:0019826)
0.1 0.3 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.1 0.8 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.3 GO:0004447 iodide peroxidase activity(GO:0004447)
0.0 0.7 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.7 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.3 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.1 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532)
0.0 0.1 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.1 GO:0004948 calcitonin receptor activity(GO:0004948)
0.0 0.1 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.2 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.3 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.1 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.0 0.2 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.8 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 2.3 GO:0005507 copper ion binding(GO:0005507)
0.0 0.2 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0 0.1 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.0 0.2 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.6 GO:0005112 Notch binding(GO:0005112)
0.0 0.4 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.3 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.1 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.0 0.4 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.7 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.1 GO:0005277 acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375)
0.0 0.1 GO:0045518 interleukin-22 receptor binding(GO:0045518)
0.0 0.1 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.0 0.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.4 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.2 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.1 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.4 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.5 GO:0008009 chemokine activity(GO:0008009)
0.0 0.1 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.4 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.1 GO:0070573 metallodipeptidase activity(GO:0070573)
0.0 0.2 GO:0050786 RAGE receptor binding(GO:0050786)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.7 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.8 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 0.7 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.4 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.6 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 1.9 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.3 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.4 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.3 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.3 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 1.7 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide