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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for SOX30

Z-value: 0.55

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Transcription factors associated with SOX30

Gene Symbol Gene ID Gene Info
SOX30
ENSG00000039600.6 SRY-box transcription factor 30

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SOX30hg19_v2_chr5_-_157079428_157079452-0.272.5e-01Click!

Activity profile of SOX30 motif

Sorted Z-values of SOX30 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr22_-_30970560 1.94 ENST00000402369.1
ENST00000406361.1
GAL3ST1
galactose-3-O-sulfotransferase 1
chr17_+_67498538 1.86 ENST00000589647.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr6_+_12290586 1.76 ENST00000379375.5
EDN1
endothelin 1
chr6_+_126240442 1.48 ENST00000448104.1
ENST00000438495.1
ENST00000444128.1
NCOA7
nuclear receptor coactivator 7
chr22_-_30970498 1.30 ENST00000431313.1
GAL3ST1
galactose-3-O-sulfotransferase 1
chr17_+_67498295 1.21 ENST00000589295.1
MAP2K6
mitogen-activated protein kinase kinase 6
chrY_+_15016013 1.20 ENST00000360160.4
ENST00000454054.1
DDX3Y
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
chr15_+_76629064 1.14 ENST00000290759.4
ISL2
ISL LIM homeobox 2
chr2_+_143635067 1.07 ENST00000264170.4
KYNU
kynureninase
chr7_-_11871815 1.06 ENST00000423059.4
THSD7A
thrombospondin, type I, domain containing 7A
chr17_-_38821373 0.84 ENST00000394052.3
KRT222
keratin 222
chr10_+_35484793 0.82 ENST00000488741.1
ENST00000474931.1
ENST00000468236.1
ENST00000344351.5
ENST00000490511.1
CREM
cAMP responsive element modulator
chr5_+_140235469 0.78 ENST00000506939.2
ENST00000307360.5
PCDHA10
protocadherin alpha 10
chr6_-_89927151 0.77 ENST00000454853.2
GABRR1
gamma-aminobutyric acid (GABA) A receptor, rho 1
chr7_-_121944491 0.73 ENST00000331178.4
ENST00000427185.2
ENST00000442488.2
FEZF1
FEZ family zinc finger 1
chr1_+_244998602 0.72 ENST00000411948.2
COX20
COX20 cytochrome C oxidase assembly factor
chrX_-_15872914 0.71 ENST00000380291.1
ENST00000545766.1
ENST00000421527.2
ENST00000329235.2
AP1S2
adaptor-related protein complex 1, sigma 2 subunit
chr2_+_232573222 0.66 ENST00000341369.7
ENST00000409683.1
PTMA
prothymosin, alpha
chr2_-_169769787 0.65 ENST00000451987.1
SPC25
SPC25, NDC80 kinetochore complex component
chr2_+_232573208 0.62 ENST00000409115.3
PTMA
prothymosin, alpha
chr2_-_157198860 0.62 ENST00000409572.1
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr12_-_10588539 0.60 ENST00000381902.2
ENST00000381901.1
ENST00000539033.1
KLRC2
NKG2-E
killer cell lectin-like receptor subfamily C, member 2
Uncharacterized protein
chrX_+_70503433 0.59 ENST00000276079.8
ENST00000373856.3
ENST00000373841.1
ENST00000420903.1
NONO
non-POU domain containing, octamer-binding
chr10_+_35415978 0.59 ENST00000429130.3
ENST00000469949.2
ENST00000460270.1
CREM
cAMP responsive element modulator
chr17_+_67498396 0.56 ENST00000588110.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr9_+_103235365 0.54 ENST00000374879.4
TMEFF1
transmembrane protein with EGF-like and two follistatin-like domains 1
chr4_-_40516560 0.52 ENST00000513473.1
RBM47
RNA binding motif protein 47
chr9_-_74383302 0.51 ENST00000377066.5
TMEM2
transmembrane protein 2
chr1_-_201476274 0.48 ENST00000340006.2
CSRP1
cysteine and glycine-rich protein 1
chr10_+_35415719 0.46 ENST00000474362.1
ENST00000374721.3
CREM
cAMP responsive element modulator
chr11_-_75236867 0.46 ENST00000376282.3
ENST00000336898.3
GDPD5
glycerophosphodiester phosphodiesterase domain containing 5
chr5_-_59481406 0.46 ENST00000546160.1
PDE4D
phosphodiesterase 4D, cAMP-specific
chr15_+_93426514 0.46 ENST00000556722.1
CHD2
chromodomain helicase DNA binding protein 2
chr18_+_68002675 0.44 ENST00000584919.1
RP11-41O4.1
Uncharacterized protein
chr6_+_22146851 0.44 ENST00000606197.1
CASC15
cancer susceptibility candidate 15 (non-protein coding)
chr16_+_87636474 0.43 ENST00000284262.2
JPH3
junctophilin 3
chr1_+_149239529 0.42 ENST00000457216.2
RP11-403I13.4
RP11-403I13.4
chr5_+_170288856 0.42 ENST00000523189.1
RANBP17
RAN binding protein 17
chr7_-_107443652 0.39 ENST00000340010.5
ENST00000422236.2
ENST00000453332.1
SLC26A3
solute carrier family 26 (anion exchanger), member 3
chr1_-_198906528 0.39 ENST00000432296.1
MIR181A1HG
MIR181A1 host gene (non-protein coding)
chr11_-_89224638 0.37 ENST00000535633.1
ENST00000263317.4
NOX4
NADPH oxidase 4
chr15_+_69857515 0.36 ENST00000559477.1
RP11-279F6.1
RP11-279F6.1
chr1_-_26231589 0.36 ENST00000374291.1
STMN1
stathmin 1
chr12_-_11036844 0.36 ENST00000428168.2
PRH1
proline-rich protein HaeIII subfamily 1
chr10_+_35416090 0.35 ENST00000354759.3
CREM
cAMP responsive element modulator
chr4_+_187148556 0.35 ENST00000264690.6
ENST00000446598.2
ENST00000414291.1
ENST00000513864.1
KLKB1
kallikrein B, plasma (Fletcher factor) 1
chr12_+_9066472 0.33 ENST00000538657.1
PHC1
polyhomeotic homolog 1 (Drosophila)
chr10_+_35415851 0.33 ENST00000374726.3
CREM
cAMP responsive element modulator
chr8_-_49533521 0.33 ENST00000523038.1
RP11-567J20.1
RP11-567J20.1
chr11_-_18548426 0.32 ENST00000357193.3
ENST00000536719.1
TSG101
tumor susceptibility 101
chr21_+_35553045 0.32 ENST00000416145.1
ENST00000430922.1
ENST00000419881.2
LINC00310
long intergenic non-protein coding RNA 310
chr5_+_60933634 0.31 ENST00000505642.1
C5orf64
chromosome 5 open reading frame 64
chr1_+_228337553 0.30 ENST00000366714.2
GJC2
gap junction protein, gamma 2, 47kDa
chr1_+_240255166 0.30 ENST00000319653.9
FMN2
formin 2
chr5_+_38148582 0.30 ENST00000508853.1
CTD-2207A17.1
CTD-2207A17.1
chr1_+_244998918 0.30 ENST00000366528.3
COX20
COX20 cytochrome C oxidase assembly factor
chr5_-_141338627 0.29 ENST00000231484.3
PCDH12
protocadherin 12
chr3_-_19988462 0.27 ENST00000344838.4
EFHB
EF-hand domain family, member B
chr2_-_158182322 0.26 ENST00000420719.2
ENST00000409216.1
ERMN
ermin, ERM-like protein
chr21_+_35552978 0.26 ENST00000428914.2
ENST00000609062.1
ENST00000609947.1
LINC00310
long intergenic non-protein coding RNA 310
chr3_+_140981456 0.26 ENST00000504264.1
ACPL2
acid phosphatase-like 2
chr1_-_156828810 0.25 ENST00000368195.3
INSRR
insulin receptor-related receptor
chr11_-_8964580 0.25 ENST00000325884.1
ASCL3
achaete-scute family bHLH transcription factor 3
chr19_-_17375527 0.25 ENST00000431146.2
ENST00000594190.1
USHBP1
Usher syndrome 1C binding protein 1
chr2_+_207804278 0.23 ENST00000272852.3
CPO
carboxypeptidase O
chr10_+_35416223 0.23 ENST00000489321.1
ENST00000427847.2
ENST00000345491.3
ENST00000395895.2
ENST00000374728.3
ENST00000487132.1
CREM
cAMP responsive element modulator
chr15_-_52944231 0.23 ENST00000546305.2
FAM214A
family with sequence similarity 214, member A
chr12_-_99288536 0.23 ENST00000549797.1
ENST00000333732.7
ENST00000341752.7
ANKS1B
ankyrin repeat and sterile alpha motif domain containing 1B
chr1_-_200379180 0.22 ENST00000294740.3
ZNF281
zinc finger protein 281
chr2_-_166060571 0.22 ENST00000360093.3
SCN3A
sodium channel, voltage-gated, type III, alpha subunit
chr6_-_139613269 0.22 ENST00000358430.3
TXLNB
taxilin beta
chr19_-_17375541 0.21 ENST00000252597.3
USHBP1
Usher syndrome 1C binding protein 1
chr11_-_85430163 0.20 ENST00000529581.1
ENST00000533577.1
SYTL2
synaptotagmin-like 2
chr12_-_11508520 0.20 ENST00000545626.1
ENST00000500254.2
PRB1
proline-rich protein BstNI subfamily 1
chr9_-_85882145 0.20 ENST00000328788.1
FRMD3
FERM domain containing 3
chr11_+_125365110 0.20 ENST00000527818.1
AP000708.1
AP000708.1
chr12_-_10251603 0.20 ENST00000457018.2
CLEC1A
C-type lectin domain family 1, member A
chr3_-_165555200 0.19 ENST00000479451.1
ENST00000540653.1
ENST00000488954.1
ENST00000264381.3
BCHE
butyrylcholinesterase
chr5_-_141338377 0.19 ENST00000510041.1
PCDH12
protocadherin 12
chr6_-_49712123 0.18 ENST00000263045.4
CRISP3
cysteine-rich secretory protein 3
chr5_+_140593509 0.18 ENST00000341948.4
PCDHB13
protocadherin beta 13
chr1_+_74701062 0.18 ENST00000326637.3
TNNI3K
TNNI3 interacting kinase
chr2_-_166060552 0.18 ENST00000283254.7
ENST00000453007.1
SCN3A
sodium channel, voltage-gated, type III, alpha subunit
chr3_-_167191814 0.18 ENST00000466903.1
ENST00000264677.4
SERPINI2
serpin peptidase inhibitor, clade I (pancpin), member 2
chr12_-_10282836 0.17 ENST00000304084.8
ENST00000353231.5
ENST00000525605.1
CLEC7A
C-type lectin domain family 7, member A
chr21_+_30672433 0.17 ENST00000451655.1
BACH1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chrX_+_70503037 0.17 ENST00000535149.1
NONO
non-POU domain containing, octamer-binding
chr2_-_166060382 0.17 ENST00000409101.3
SCN3A
sodium channel, voltage-gated, type III, alpha subunit
chr2_-_158182410 0.17 ENST00000419116.2
ENST00000410096.1
ERMN
ermin, ERM-like protein
chr12_-_10251539 0.17 ENST00000420265.2
CLEC1A
C-type lectin domain family 1, member A
chr4_-_176733897 0.16 ENST00000393658.2
GPM6A
glycoprotein M6A
chr17_+_47448102 0.16 ENST00000576461.1
RP11-81K2.1
Uncharacterized protein
chr7_-_92855762 0.16 ENST00000453812.2
ENST00000394468.2
HEPACAM2
HEPACAM family member 2
chr12_-_10251576 0.16 ENST00000315330.4
CLEC1A
C-type lectin domain family 1, member A
chr16_+_20499024 0.15 ENST00000593357.1
AC137056.1
Uncharacterized protein; cDNA FLJ34659 fis, clone KIDNE2018863
chr1_+_185703513 0.15 ENST00000271588.4
ENST00000367492.2
HMCN1
hemicentin 1
chr10_-_28270795 0.15 ENST00000545014.1
ARMC4
armadillo repeat containing 4
chr5_+_140729649 0.15 ENST00000523390.1
PCDHGB1
protocadherin gamma subfamily B, 1
chr4_-_69111401 0.14 ENST00000332644.5
TMPRSS11B
transmembrane protease, serine 11B
chr11_-_102323489 0.14 ENST00000361236.3
TMEM123
transmembrane protein 123
chr3_+_19988736 0.14 ENST00000443878.1
RAB5A
RAB5A, member RAS oncogene family
chr1_-_167883353 0.14 ENST00000545172.1
ADCY10
adenylate cyclase 10 (soluble)
chr9_-_134145880 0.14 ENST00000372269.3
ENST00000464831.1
FAM78A
family with sequence similarity 78, member A
chr20_+_30555805 0.13 ENST00000562532.2
XKR7
XK, Kell blood group complex subunit-related family, member 7
chr14_+_101299520 0.13 ENST00000455531.1
MEG3
maternally expressed 3 (non-protein coding)
chr2_+_223536428 0.13 ENST00000446656.3
MOGAT1
monoacylglycerol O-acyltransferase 1
chr3_-_8686479 0.12 ENST00000544814.1
ENST00000427408.1
SSUH2
ssu-2 homolog (C. elegans)
chr19_+_107471 0.12 ENST00000585993.1
OR4F17
olfactory receptor, family 4, subfamily F, member 17
chr20_-_5426332 0.12 ENST00000420529.1
LINC00658
long intergenic non-protein coding RNA 658
chr20_-_5426380 0.11 ENST00000609252.1
ENST00000422352.1
LINC00658
long intergenic non-protein coding RNA 658
chr18_-_53804580 0.11 ENST00000590484.1
ENST00000589293.1
ENST00000587904.1
ENST00000591974.1
RP11-456O19.4
RP11-456O19.4
chr11_-_85430088 0.11 ENST00000533057.1
ENST00000533892.1
SYTL2
synaptotagmin-like 2
chr12_+_80750134 0.10 ENST00000546620.1
OTOGL
otogelin-like
chr7_-_44229022 0.10 ENST00000403799.3
GCK
glucokinase (hexokinase 4)
chr6_+_131958436 0.10 ENST00000357639.3
ENST00000543135.1
ENST00000427148.2
ENST00000358229.5
ENPP3
ectonucleotide pyrophosphatase/phosphodiesterase 3
chrX_+_102192200 0.10 ENST00000218249.5
RAB40AL
RAB40A, member RAS oncogene family-like
chr6_-_128222103 0.09 ENST00000434358.1
ENST00000543064.1
ENST00000368248.2
THEMIS
thymocyte selection associated
chr12_-_11002063 0.09 ENST00000544994.1
ENST00000228811.4
ENST00000540107.1
PRR4
proline rich 4 (lacrimal)
chr12_+_27623565 0.08 ENST00000535986.1
SMCO2
single-pass membrane protein with coiled-coil domains 2
chr11_-_85430204 0.08 ENST00000389958.3
ENST00000527794.1
SYTL2
synaptotagmin-like 2
chr3_-_122283424 0.08 ENST00000477522.2
ENST00000360356.2
PARP9
poly (ADP-ribose) polymerase family, member 9
chr2_+_27719697 0.08 ENST00000264717.2
ENST00000424318.2
GCKR
glucokinase (hexokinase 4) regulator
chr6_-_161085291 0.07 ENST00000316300.5
LPA
lipoprotein, Lp(a)
chr10_+_70480963 0.07 ENST00000265872.6
ENST00000535016.1
ENST00000538031.1
ENST00000543719.1
ENST00000539539.1
ENST00000543225.1
ENST00000536012.1
ENST00000494903.2
CCAR1
cell division cycle and apoptosis regulator 1
chr12_-_99288986 0.06 ENST00000552407.1
ENST00000551613.1
ENST00000548447.1
ENST00000546364.3
ENST00000552748.1
ANKS1B
ankyrin repeat and sterile alpha motif domain containing 1B
chr4_+_71458012 0.06 ENST00000449493.2
AMBN
ameloblastin (enamel matrix protein)
chr12_+_11081828 0.06 ENST00000381847.3
ENST00000396400.3
PRH2
proline-rich protein HaeIII subfamily 2
chr1_-_167883327 0.05 ENST00000476818.2
ENST00000367851.4
ENST00000367848.1
ADCY10
adenylate cyclase 10 (soluble)
chr4_+_71457970 0.05 ENST00000322937.6
AMBN
ameloblastin (enamel matrix protein)
chr14_+_52456193 0.05 ENST00000261700.3
C14orf166
chromosome 14 open reading frame 166
chr13_+_98795664 0.04 ENST00000376581.5
FARP1
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr12_-_10282742 0.03 ENST00000298523.5
ENST00000396484.2
ENST00000310002.4
CLEC7A
C-type lectin domain family 7, member A
chr11_-_85430356 0.03 ENST00000526999.1
SYTL2
synaptotagmin-like 2
chr1_-_85930246 0.03 ENST00000426972.3
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr12_+_95611516 0.02 ENST00000436874.1
VEZT
vezatin, adherens junctions transmembrane protein
chr7_-_122840015 0.02 ENST00000194130.2
SLC13A1
solute carrier family 13 (sodium/sulfate symporter), member 1
chr5_+_139175380 0.02 ENST00000274710.3
PSD2
pleckstrin and Sec7 domain containing 2
chr18_+_7946941 0.01 ENST00000444013.1
PTPRM
protein tyrosine phosphatase, receptor type, M
chr12_-_11548496 0.01 ENST00000389362.4
ENST00000565533.1
ENST00000546254.1
PRB2
PRB1
proline-rich protein BstNI subfamily 2
proline-rich protein BstNI subfamily 1
chr1_-_201476220 0.01 ENST00000526723.1
ENST00000524951.1
CSRP1
cysteine and glycine-rich protein 1
chr5_+_140739537 0.00 ENST00000522605.1
PCDHGB2
protocadherin gamma subfamily B, 2
chr10_-_61122934 0.00 ENST00000512919.1
FAM13C
family with sequence similarity 13, member C

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX30

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.6 GO:0072709 cellular response to sorbitol(GO:0072709)
0.4 1.8 GO:0060585 nitric oxide transport(GO:0030185) negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.3 1.1 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.3 1.1 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.2 3.2 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.2 0.6 GO:0051866 general adaptation syndrome(GO:0051866)
0.1 0.7 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 0.4 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541) positive regulation of fibrinolysis(GO:0051919)
0.1 0.3 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774) regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
0.1 0.3 GO:0051758 homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.1 0.2 GO:0014016 neuroblast differentiation(GO:0014016)
0.1 0.8 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.1 1.5 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.1 0.3 GO:0071469 cellular response to alkaline pH(GO:0071469)
0.1 0.4 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.0 1.0 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.5 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.5 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.3 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0 2.8 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.1 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.4 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.0 0.5 GO:0040034 regulation of development, heterochronic(GO:0040034) regulation of timing of cell differentiation(GO:0048505)
0.0 0.4 GO:0045852 pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.0 0.1 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.1 GO:0046373 arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373)
0.0 0.1 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.1 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.0 0.8 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.5 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 1.2 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.7 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.1 GO:0009732 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.0 0.3 GO:0010644 cell communication by electrical coupling(GO:0010644)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.8 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.1 0.6 GO:0031262 Ndc80 complex(GO:0031262)
0.1 0.8 GO:0042382 paraspeckles(GO:0042382)
0.0 0.4 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.4 GO:0033269 internode region of axon(GO:0033269)
0.0 0.8 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.6 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.4 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.3 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.4 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.2 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.3 GO:0005922 connexon complex(GO:0005922)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.8 GO:0031708 endothelin B receptor binding(GO:0031708)
0.3 3.2 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.2 1.1 GO:0016823 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.2 0.5 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.1 2.8 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 0.6 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.1 2.8 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.2 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.0 0.5 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.3 GO:0046790 virion binding(GO:0046790)
0.0 0.3 GO:1903763 gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
0.0 0.4 GO:0019826 oxygen sensor activity(GO:0019826)
0.0 0.4 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.8 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.1 GO:0030345 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0 0.1 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.0 0.5 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.1 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.0 0.4 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.6 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.1 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.0 0.6 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 1.5 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.4 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.2 GO:0031013 troponin I binding(GO:0031013)
0.0 0.1 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.4 GO:0099604 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0 0.1 GO:0004396 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 1.2 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.0 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 2.8 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.8 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 1.8 PID ENDOTHELIN PATHWAY Endothelins
0.0 1.5 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.6 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 1.1 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 3.2 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.7 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.3 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.8 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 0.4 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.3 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly