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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for SOX6

Z-value: 1.02

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Transcription factors associated with SOX6

Gene Symbol Gene ID Gene Info
SOX6
ENSG00000110693.11 SRY-box transcription factor 6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SOX6hg19_v2_chr11_-_16430399_16430440-0.913.7e-08Click!

Activity profile of SOX6 motif

Sorted Z-values of SOX6 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_88896819 4.78 ENST00000237623.7
ENST00000395080.3
ENST00000508233.1
ENST00000360804.4
SPP1
secreted phosphoprotein 1
chr4_+_41614909 3.46 ENST00000509454.1
ENST00000396595.3
ENST00000381753.4
LIMCH1
LIM and calponin homology domains 1
chr6_-_64029879 3.35 ENST00000370658.5
ENST00000485906.2
ENST00000370657.4
LGSN
lengsin, lens protein with glutamine synthetase domain
chr9_-_131940526 3.21 ENST00000372491.2
IER5L
immediate early response 5-like
chr17_+_67498538 2.87 ENST00000589647.1
MAP2K6
mitogen-activated protein kinase kinase 6
chrX_+_12993202 2.82 ENST00000451311.2
ENST00000380636.1
TMSB4X
thymosin beta 4, X-linked
chr2_+_27070964 2.66 ENST00000288699.6
DPYSL5
dihydropyrimidinase-like 5
chr6_-_127840336 2.58 ENST00000525778.1
SOGA3
SOGA family member 3
chr4_+_41614720 2.55 ENST00000509277.1
LIMCH1
LIM and calponin homology domains 1
chr6_-_127840021 2.47 ENST00000465909.2
SOGA3
SOGA family member 3
chr17_-_19648683 2.45 ENST00000573368.1
ENST00000457500.2
ALDH3A1
aldehyde dehydrogenase 3 family, member A1
chr7_-_107968999 2.19 ENST00000456431.1
NRCAM
neuronal cell adhesion molecule
chr15_-_88799948 2.18 ENST00000394480.2
NTRK3
neurotrophic tyrosine kinase, receptor, type 3
chr2_-_175202151 2.17 ENST00000595354.1
AC018470.1
Uncharacterized protein FLJ46347
chr17_+_67498295 2.09 ENST00000589295.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr17_-_19648916 2.08 ENST00000444455.1
ENST00000439102.2
ALDH3A1
aldehyde dehydrogenase 3 family, member A1
chr12_-_53320245 2.06 ENST00000552150.1
KRT8
keratin 8
chr15_-_56035177 2.01 ENST00000389286.4
ENST00000561292.1
PRTG
protogenin
chr6_+_126240442 2.00 ENST00000448104.1
ENST00000438495.1
ENST00000444128.1
NCOA7
nuclear receptor coactivator 7
chr8_-_124741451 1.95 ENST00000520519.1
ANXA13
annexin A13
chr5_-_176836577 1.92 ENST00000253496.3
F12
coagulation factor XII (Hageman factor)
chr2_+_27071045 1.89 ENST00000401478.1
DPYSL5
dihydropyrimidinase-like 5
chr12_-_58146048 1.89 ENST00000547281.1
ENST00000546489.1
ENST00000552388.1
ENST00000540325.1
ENST00000312990.6
CDK4
cyclin-dependent kinase 4
chr2_-_86564776 1.88 ENST00000165698.5
ENST00000541910.1
ENST00000535845.1
REEP1
receptor accessory protein 1
chr17_-_19648416 1.85 ENST00000426645.2
ALDH3A1
aldehyde dehydrogenase 3 family, member A1
chr15_-_54025300 1.85 ENST00000559418.1
WDR72
WD repeat domain 72
chr5_+_140254884 1.84 ENST00000398631.2
PCDHA12
protocadherin alpha 12
chr22_-_30970560 1.81 ENST00000402369.1
ENST00000406361.1
GAL3ST1
galactose-3-O-sulfotransferase 1
chr17_+_64961026 1.74 ENST00000262138.3
CACNG4
calcium channel, voltage-dependent, gamma subunit 4
chr22_-_42336209 1.73 ENST00000472374.2
CENPM
centromere protein M
chr14_+_103589789 1.72 ENST00000558056.1
ENST00000560869.1
TNFAIP2
tumor necrosis factor, alpha-induced protein 2
chr10_-_25241499 1.67 ENST00000376378.1
ENST00000376376.3
ENST00000320152.6
PRTFDC1
phosphoribosyl transferase domain containing 1
chr15_+_80696666 1.63 ENST00000303329.4
ARNT2
aryl-hydrocarbon receptor nuclear translocator 2
chr7_-_107968921 1.62 ENST00000442580.1
NRCAM
neuronal cell adhesion molecule
chr6_-_127840048 1.60 ENST00000467753.1
SOGA3
SOGA family member 3
chr12_-_58145604 1.58 ENST00000552254.1
CDK4
cyclin-dependent kinase 4
chr16_+_30406423 1.52 ENST00000524644.1
ZNF48
zinc finger protein 48
chr17_-_79849438 1.51 ENST00000331204.4
ENST00000505490.2
ALYREF
Aly/REF export factor
chr2_+_25264933 1.48 ENST00000401432.3
ENST00000403714.3
EFR3B
EFR3 homolog B (S. cerevisiae)
chr3_-_148939598 1.47 ENST00000455472.3
CP
ceruloplasmin (ferroxidase)
chr15_-_80695917 1.46 ENST00000559008.1
RP11-210M15.2
Uncharacterized protein
chr5_-_59481406 1.46 ENST00000546160.1
PDE4D
phosphodiesterase 4D, cAMP-specific
chr7_+_139528952 1.43 ENST00000416849.2
ENST00000436047.2
ENST00000414508.2
ENST00000448866.1
TBXAS1
thromboxane A synthase 1 (platelet)
chr17_+_26698677 1.42 ENST00000457710.3
SARM1
sterile alpha and TIR motif containing 1
chr17_-_46716647 1.39 ENST00000608940.1
RP11-357H14.17
RP11-357H14.17
chr21_+_30672433 1.34 ENST00000451655.1
BACH1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr8_+_27631903 1.34 ENST00000305188.8
ESCO2
establishment of sister chromatid cohesion N-acetyltransferase 2
chr2_+_170590321 1.34 ENST00000392647.2
KLHL23
kelch-like family member 23
chr15_-_82338460 1.34 ENST00000558133.1
ENST00000329713.4
MEX3B
mex-3 RNA binding family member B
chr3_-_148939835 1.30 ENST00000264613.6
CP
ceruloplasmin (ferroxidase)
chr1_-_201476220 1.27 ENST00000526723.1
ENST00000524951.1
CSRP1
cysteine and glycine-rich protein 1
chr12_+_22778009 1.23 ENST00000266517.4
ENST00000335148.3
ETNK1
ethanolamine kinase 1
chr21_+_33784670 1.23 ENST00000300255.2
EVA1C
eva-1 homolog C (C. elegans)
chr11_-_85430163 1.23 ENST00000529581.1
ENST00000533577.1
SYTL2
synaptotagmin-like 2
chr19_+_49468558 1.22 ENST00000331825.6
FTL
ferritin, light polypeptide
chr14_-_95236551 1.21 ENST00000238558.3
GSC
goosecoid homeobox
chr19_-_10047219 1.20 ENST00000264833.4
OLFM2
olfactomedin 2
chr17_-_53046058 1.19 ENST00000571584.1
ENST00000299335.3
COX11
cytochrome c oxidase assembly homolog 11 (yeast)
chr10_-_13390270 1.15 ENST00000378614.4
ENST00000545675.1
ENST00000327347.5
SEPHS1
selenophosphate synthetase 1
chr1_-_201476274 1.14 ENST00000340006.2
CSRP1
cysteine and glycine-rich protein 1
chr7_-_50628745 1.14 ENST00000380984.4
ENST00000357936.5
ENST00000426377.1
DDC
dopa decarboxylase (aromatic L-amino acid decarboxylase)
chr19_+_38397839 1.12 ENST00000222345.6
SIPA1L3
signal-induced proliferation-associated 1 like 3
chr16_+_15528332 1.12 ENST00000566490.1
C16orf45
chromosome 16 open reading frame 45
chr17_-_42441204 1.12 ENST00000293443.7
FAM171A2
family with sequence similarity 171, member A2
chr1_-_26232951 1.09 ENST00000426559.2
ENST00000455785.2
STMN1
stathmin 1
chr6_-_108278456 1.07 ENST00000429168.1
SEC63
SEC63 homolog (S. cerevisiae)
chr12_-_58146128 1.07 ENST00000551800.1
ENST00000549606.1
ENST00000257904.6
CDK4
cyclin-dependent kinase 4
chr4_-_105416039 1.06 ENST00000394767.2
CXXC4
CXXC finger protein 4
chr11_-_85430088 1.05 ENST00000533057.1
ENST00000533892.1
SYTL2
synaptotagmin-like 2
chr17_+_21729899 1.04 ENST00000583708.1
UBBP4
ubiquitin B pseudogene 4
chr6_-_127840453 1.04 ENST00000556132.1
SOGA3
SOGA family member 3
chr20_+_34679725 1.03 ENST00000432589.1
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr16_-_29478016 1.03 ENST00000549858.1
ENST00000551411.1
RP11-345J4.3
Uncharacterized protein
chr11_-_85430204 1.02 ENST00000389958.3
ENST00000527794.1
SYTL2
synaptotagmin-like 2
chr7_+_69064566 1.01 ENST00000403018.2
AUTS2
autism susceptibility candidate 2
chr11_+_125496619 1.01 ENST00000532669.1
ENST00000278916.3
CHEK1
checkpoint kinase 1
chr10_+_22605304 1.01 ENST00000475460.2
ENST00000602390.1
ENST00000489125.2
ENST00000456711.1
ENST00000444869.1
COMMD3-BMI1
COMMD3
COMMD3-BMI1 readthrough
COMM domain containing 3
chr16_+_1832902 1.00 ENST00000262302.9
ENST00000563136.1
ENST00000565987.1
ENST00000543305.1
ENST00000568287.1
ENST00000565134.1
NUBP2
nucleotide binding protein 2
chr17_+_67498396 1.00 ENST00000588110.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr16_+_30205754 1.00 ENST00000354723.6
ENST00000355544.5
SULT1A3
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
chr5_+_140235469 1.00 ENST00000506939.2
ENST00000307360.5
PCDHA10
protocadherin alpha 10
chr16_+_30406721 0.99 ENST00000320159.2
ZNF48
zinc finger protein 48
chr5_+_140201183 0.98 ENST00000529619.1
ENST00000529859.1
ENST00000378126.3
PCDHA5
protocadherin alpha 5
chr17_+_21729593 0.97 ENST00000581769.1
ENST00000584755.1
UBBP4
ubiquitin B pseudogene 4
chr10_+_22605374 0.95 ENST00000448361.1
COMMD3
COMM domain containing 3
chr9_-_74383302 0.94 ENST00000377066.5
TMEM2
transmembrane protein 2
chr19_-_44124019 0.93 ENST00000300811.3
ZNF428
zinc finger protein 428
chr18_-_74728998 0.92 ENST00000359645.3
ENST00000397875.3
ENST00000397869.3
ENST00000578193.1
ENST00000578873.1
ENST00000397866.4
ENST00000528160.1
ENST00000527041.1
ENST00000526111.1
ENST00000397865.5
ENST00000382582.3
MBP
myelin basic protein
chr18_+_55102917 0.91 ENST00000491143.2
ONECUT2
one cut homeobox 2
chr3_-_123339343 0.89 ENST00000578202.1
MYLK
myosin light chain kinase
chr17_+_27920486 0.88 ENST00000394859.3
ANKRD13B
ankyrin repeat domain 13B
chr16_-_73082274 0.88 ENST00000268489.5
ZFHX3
zinc finger homeobox 3
chrX_+_9433289 0.88 ENST00000422314.1
TBL1X
transducin (beta)-like 1X-linked
chr2_-_157198860 0.88 ENST00000409572.1
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr17_+_40119801 0.88 ENST00000585452.1
CNP
2',3'-cyclic nucleotide 3' phosphodiesterase
chr3_-_114790179 0.86 ENST00000462705.1
ZBTB20
zinc finger and BTB domain containing 20
chr6_+_13925098 0.85 ENST00000488300.1
ENST00000544682.1
ENST00000420478.2
RNF182
ring finger protein 182
chr15_-_52043722 0.85 ENST00000454181.2
LYSMD2
LysM, putative peptidoglycan-binding, domain containing 2
chr16_-_67970990 0.84 ENST00000358514.4
PSMB10
proteasome (prosome, macropain) subunit, beta type, 10
chr8_+_126442563 0.84 ENST00000311922.3
TRIB1
tribbles pseudokinase 1
chr2_+_10262857 0.84 ENST00000304567.5
RRM2
ribonucleotide reductase M2
chr2_-_86564740 0.84 ENST00000540790.1
ENST00000428491.1
REEP1
receptor accessory protein 1
chr7_+_87563557 0.84 ENST00000439864.1
ENST00000412441.1
ENST00000398201.4
ENST00000265727.7
ENST00000315984.7
ENST00000398209.3
ADAM22
ADAM metallopeptidase domain 22
chr7_-_99699538 0.83 ENST00000343023.6
ENST00000303887.5
MCM7
minichromosome maintenance complex component 7
chr14_-_51027838 0.83 ENST00000555216.1
MAP4K5
mitogen-activated protein kinase kinase kinase kinase 5
chr16_-_31085033 0.82 ENST00000414399.1
ZNF668
zinc finger protein 668
chr22_-_21984282 0.82 ENST00000398873.3
ENST00000292778.6
YDJC
YdjC homolog (bacterial)
chr4_+_95129061 0.82 ENST00000354268.4
SMARCAD1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr6_-_3227877 0.81 ENST00000259818.7
TUBB2B
tubulin, beta 2B class IIb
chr17_+_21730180 0.81 ENST00000584398.1
UBBP4
ubiquitin B pseudogene 4
chr1_+_240255166 0.80 ENST00000319653.9
FMN2
formin 2
chr20_-_52645231 0.80 ENST00000448484.1
BCAS1
breast carcinoma amplified sequence 1
chr12_+_69979446 0.79 ENST00000543146.2
CCT2
chaperonin containing TCP1, subunit 2 (beta)
chr9_-_39239171 0.78 ENST00000358144.2
CNTNAP3
contactin associated protein-like 3
chr18_+_3450161 0.77 ENST00000551402.1
ENST00000577543.1
TGIF1
TGFB-induced factor homeobox 1
chr10_+_35416223 0.77 ENST00000489321.1
ENST00000427847.2
ENST00000345491.3
ENST00000395895.2
ENST00000374728.3
ENST00000487132.1
CREM
cAMP responsive element modulator
chrX_+_70503433 0.77 ENST00000276079.8
ENST00000373856.3
ENST00000373841.1
ENST00000420903.1
NONO
non-POU domain containing, octamer-binding
chr12_+_9066472 0.76 ENST00000538657.1
PHC1
polyhomeotic homolog 1 (Drosophila)
chr1_-_26233423 0.73 ENST00000357865.2
STMN1
stathmin 1
chr17_-_39041479 0.73 ENST00000167588.3
KRT20
keratin 20
chr2_-_217560248 0.72 ENST00000233813.4
IGFBP5
insulin-like growth factor binding protein 5
chr15_+_77223960 0.72 ENST00000394885.3
RCN2
reticulocalbin 2, EF-hand calcium binding domain
chr4_-_103266219 0.72 ENST00000394833.2
SLC39A8
solute carrier family 39 (zinc transporter), member 8
chr5_-_65018834 0.71 ENST00000506816.1
SGTB
small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta
chr2_-_47572207 0.70 ENST00000441997.1
AC073283.4
AC073283.4
chr11_+_36317830 0.70 ENST00000530639.1
PRR5L
proline rich 5 like
chrX_+_129473916 0.69 ENST00000545805.1
ENST00000543953.1
ENST00000218197.5
SLC25A14
solute carrier family 25 (mitochondrial carrier, brain), member 14
chr9_-_130712995 0.69 ENST00000373084.4
FAM102A
family with sequence similarity 102, member A
chr10_-_75351088 0.68 ENST00000451492.1
ENST00000413442.1
USP54
ubiquitin specific peptidase 54
chr19_-_5340730 0.68 ENST00000372412.4
ENST00000357368.4
ENST00000262963.6
ENST00000348075.2
ENST00000353284.2
PTPRS
protein tyrosine phosphatase, receptor type, S
chr18_+_3449821 0.67 ENST00000407501.2
ENST00000405385.3
ENST00000546979.1
TGIF1
TGFB-induced factor homeobox 1
chr7_-_121944491 0.67 ENST00000331178.4
ENST00000427185.2
ENST00000442488.2
FEZF1
FEZ family zinc finger 1
chrX_-_153599578 0.67 ENST00000360319.4
ENST00000344736.4
FLNA
filamin A, alpha
chr3_-_123339418 0.66 ENST00000583087.1
MYLK
myosin light chain kinase
chr5_+_140213815 0.65 ENST00000525929.1
ENST00000378125.3
PCDHA7
protocadherin alpha 7
chr15_+_101402041 0.64 ENST00000558475.1
ENST00000558641.1
ENST00000559673.1
RP11-66B24.1
RP11-66B24.1
chr6_+_32936942 0.64 ENST00000496118.2
BRD2
bromodomain containing 2
chr11_-_75236867 0.63 ENST00000376282.3
ENST00000336898.3
GDPD5
glycerophosphodiester phosphodiesterase domain containing 5
chr15_+_93426514 0.63 ENST00000556722.1
CHD2
chromodomain helicase DNA binding protein 2
chr1_+_228337553 0.62 ENST00000366714.2
GJC2
gap junction protein, gamma 2, 47kDa
chr16_+_2083265 0.62 ENST00000565855.1
ENST00000566198.1
SLC9A3R2
solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
chr5_-_173043591 0.61 ENST00000285908.5
ENST00000480951.1
ENST00000311086.4
BOD1
biorientation of chromosomes in cell division 1
chr17_+_72667239 0.61 ENST00000402449.4
RAB37
RAB37, member RAS oncogene family
chr17_+_53046096 0.61 ENST00000376352.2
ENST00000299341.4
ENST00000405898.1
ENST00000434978.2
ENST00000398391.2
STXBP4
syntaxin binding protein 4
chr2_+_46926326 0.60 ENST00000394861.2
SOCS5
suppressor of cytokine signaling 5
chr19_+_50354430 0.60 ENST00000599732.1
PTOV1
prostate tumor overexpressed 1
chr2_+_120517174 0.60 ENST00000263708.2
PTPN4
protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
chr11_-_102323489 0.60 ENST00000361236.3
TMEM123
transmembrane protein 123
chr11_+_65999265 0.60 ENST00000528935.1
PACS1
phosphofurin acidic cluster sorting protein 1
chr3_+_19988736 0.59 ENST00000443878.1
RAB5A
RAB5A, member RAS oncogene family
chr17_-_56065540 0.59 ENST00000583932.1
VEZF1
vascular endothelial zinc finger 1
chr9_+_108463234 0.59 ENST00000374688.1
TMEM38B
transmembrane protein 38B
chr15_+_89631647 0.59 ENST00000569550.1
ENST00000565066.1
ENST00000565973.1
ABHD2
abhydrolase domain containing 2
chr7_-_107643567 0.58 ENST00000393559.1
ENST00000439976.1
ENST00000393560.1
LAMB1
laminin, beta 1
chr1_+_182808474 0.58 ENST00000367549.3
DHX9
DEAH (Asp-Glu-Ala-His) box helicase 9
chr2_-_231989808 0.58 ENST00000258400.3
HTR2B
5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
chr15_+_81293254 0.58 ENST00000267984.2
MESDC1
mesoderm development candidate 1
chr3_+_112930306 0.58 ENST00000495514.1
BOC
BOC cell adhesion associated, oncogene regulated
chr1_-_26232522 0.57 ENST00000399728.1
STMN1
stathmin 1
chr7_-_128415844 0.57 ENST00000249389.2
OPN1SW
opsin 1 (cone pigments), short-wave-sensitive
chr3_+_39509070 0.57 ENST00000354668.4
ENST00000428261.1
ENST00000420739.1
ENST00000415443.1
ENST00000447324.1
ENST00000383754.3
MOBP
myelin-associated oligodendrocyte basic protein
chr10_+_35415851 0.57 ENST00000374726.3
CREM
cAMP responsive element modulator
chrX_+_12993336 0.56 ENST00000380635.1
TMSB4X
thymosin beta 4, X-linked
chr3_+_39509163 0.56 ENST00000436143.2
ENST00000441980.2
ENST00000311042.6
MOBP
myelin-associated oligodendrocyte basic protein
chr16_+_3162557 0.56 ENST00000382192.3
ENST00000219091.4
ENST00000444510.2
ENST00000414351.1
ZNF205
zinc finger protein 205
chr19_-_17375527 0.56 ENST00000431146.2
ENST00000594190.1
USHBP1
Usher syndrome 1C binding protein 1
chr19_+_50354462 0.56 ENST00000601675.1
PTOV1
prostate tumor overexpressed 1
chr17_-_49124230 0.54 ENST00000510283.1
ENST00000510855.1
SPAG9
sperm associated antigen 9
chr9_-_123476719 0.54 ENST00000373930.3
MEGF9
multiple EGF-like-domains 9
chrX_-_63425561 0.54 ENST00000374869.3
ENST00000330258.3
AMER1
APC membrane recruitment protein 1
chr11_-_76155618 0.54 ENST00000530759.1
RP11-111M22.3
RP11-111M22.3
chr5_-_176037105 0.54 ENST00000303991.4
GPRIN1
G protein regulated inducer of neurite outgrowth 1
chr12_-_49582978 0.54 ENST00000301071.7
TUBA1A
tubulin, alpha 1a
chr20_-_17511962 0.53 ENST00000377873.3
BFSP1
beaded filament structural protein 1, filensin
chr1_-_212004090 0.53 ENST00000366997.4
LPGAT1
lysophosphatidylglycerol acyltransferase 1
chr22_-_39052300 0.53 ENST00000355830.6
FAM227A
family with sequence similarity 227, member A
chr22_-_22292934 0.52 ENST00000538191.1
ENST00000424647.1
ENST00000407142.1
PPM1F
protein phosphatase, Mg2+/Mn2+ dependent, 1F
chr17_-_6524159 0.52 ENST00000589033.1
KIAA0753
KIAA0753
chr14_+_50234827 0.52 ENST00000554589.1
ENST00000557247.1
KLHDC2
kelch domain containing 2
chr6_+_64282447 0.51 ENST00000370650.2
ENST00000578299.1
PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr4_+_95128748 0.51 ENST00000359052.4
SMARCAD1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr15_+_57211318 0.51 ENST00000557947.1
TCF12
transcription factor 12
chr14_+_20215587 0.50 ENST00000331723.1
OR4Q3
olfactory receptor, family 4, subfamily Q, member 3
chr3_-_8686479 0.50 ENST00000544814.1
ENST00000427408.1
SSUH2
ssu-2 homolog (C. elegans)
chr5_-_67730240 0.50 ENST00000507733.1
CTC-537E7.3
CTC-537E7.3
chr2_+_61293021 0.49 ENST00000402291.1
KIAA1841
KIAA1841
chr11_+_63974135 0.49 ENST00000544997.1
ENST00000345728.5
ENST00000279227.5
FERMT3
fermitin family member 3
chr4_-_103266355 0.49 ENST00000424970.2
SLC39A8
solute carrier family 39 (zinc transporter), member 8
chrX_+_129473859 0.49 ENST00000424447.1
SLC25A14
solute carrier family 25 (mitochondrial carrier, brain), member 14
chr2_+_70056762 0.49 ENST00000282570.3
GMCL1
germ cell-less, spermatogenesis associated 1
chr17_-_72358001 0.49 ENST00000375366.3
BTBD17
BTB (POZ) domain containing 17
chr4_+_95128996 0.48 ENST00000457823.2
SMARCAD1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr1_+_244998602 0.48 ENST00000411948.2
COX20
COX20 cytochrome C oxidase assembly factor
chr17_+_52978156 0.47 ENST00000348161.4
TOM1L1
target of myb1 (chicken)-like 1
chr16_-_29466285 0.47 ENST00000330978.3
BOLA2
bolA family member 2
chr3_-_57583052 0.46 ENST00000496292.1
ENST00000489843.1
ARF4
ADP-ribosylation factor 4
chr12_+_95611536 0.46 ENST00000549002.1
VEZT
vezatin, adherens junctions transmembrane protein
chr2_+_27805880 0.46 ENST00000379717.1
ENST00000355467.4
ENST00000556601.1
ENST00000416005.2
ZNF512
zinc finger protein 512
chr7_-_107643674 0.45 ENST00000222399.6
LAMB1
laminin, beta 1
chr17_+_12859080 0.45 ENST00000583608.1
ARHGAP44
Rho GTPase activating protein 44

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 4.8 GO:2000866 positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
1.2 6.0 GO:0072709 cellular response to sorbitol(GO:0072709)
0.6 1.9 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541) positive regulation of fibrinolysis(GO:0051919)
0.6 0.6 GO:0010644 cell communication by electrical coupling(GO:0010644)
0.6 1.7 GO:1901069 guanosine-containing compound catabolic process(GO:1901069)
0.5 2.2 GO:0052026 modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.4 3.4 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.4 1.2 GO:0016260 selenocysteine biosynthetic process(GO:0016260)
0.4 1.1 GO:0052314 phytoalexin metabolic process(GO:0052314)
0.4 1.1 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.3 2.4 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.3 0.9 GO:0051866 general adaptation syndrome(GO:0051866)
0.3 2.4 GO:1904637 response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
0.3 0.8 GO:0051758 homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.3 0.8 GO:0051086 chaperone mediated protein folding independent of cofactor(GO:0051086)
0.2 0.7 GO:1904204 regulation of skeletal muscle hypertrophy(GO:1904204)
0.2 3.8 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.2 3.5 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.2 0.7 GO:0034164 negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.2 1.3 GO:0034421 post-translational protein acetylation(GO:0034421)
0.2 0.7 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.2 0.9 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.2 1.1 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.2 1.0 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.2 1.2 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.2 0.7 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.2 1.5 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.2 0.8 GO:0045658 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.2 1.0 GO:0010767 regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage(GO:0010767) histone H3-T11 phosphorylation(GO:0035407)
0.2 0.9 GO:1904209 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.2 1.2 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.2 1.1 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.1 1.9 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.1 1.5 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1 0.6 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.1 1.1 GO:1903976 negative regulation of glial cell migration(GO:1903976)
0.1 3.1 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.1 1.4 GO:0034128 negative regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034128)
0.1 1.0 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.1 2.1 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.1 0.6 GO:0035549 positive regulation of interferon-beta secretion(GO:0035549)
0.1 2.2 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.1 0.7 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 0.4 GO:0090149 mitochondrial membrane fission(GO:0090149)
0.1 0.4 GO:1990523 bone regeneration(GO:1990523)
0.1 1.2 GO:0015691 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.1 2.7 GO:0006825 copper ion transport(GO:0006825)
0.1 0.8 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.1 0.4 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.1 0.5 GO:0044571 [2Fe-2S] cluster assembly(GO:0044571)
0.1 0.6 GO:0010728 positive regulation of hydrogen peroxide metabolic process(GO:0010726) regulation of hydrogen peroxide biosynthetic process(GO:0010728)
0.1 1.8 GO:0070166 enamel mineralization(GO:0070166)
0.1 1.5 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.1 1.7 GO:0051601 exocyst localization(GO:0051601)
0.1 0.4 GO:0010157 response to chlorate(GO:0010157)
0.1 0.5 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.1 0.4 GO:0098886 modification of dendritic spine(GO:0098886)
0.1 0.3 GO:0035262 gonad morphogenesis(GO:0035262)
0.1 0.3 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.1 0.2 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.1 0.5 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.1 0.5 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.1 1.2 GO:0014029 neural crest formation(GO:0014029)
0.1 0.6 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.1 1.8 GO:0070933 histone H4 deacetylation(GO:0070933)
0.1 1.1 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.1 0.4 GO:0060979 vasculogenesis involved in coronary vascular morphogenesis(GO:0060979)
0.1 0.6 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.1 0.8 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 0.2 GO:0001543 ovarian follicle rupture(GO:0001543)
0.1 0.4 GO:1902731 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) negative regulation of chondrocyte proliferation(GO:1902731)
0.1 1.4 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.1 0.8 GO:1902669 positive regulation of axon guidance(GO:1902669)
0.1 0.5 GO:0033632 regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.1 0.2 GO:0002728 negative regulation of natural killer cell cytokine production(GO:0002728)
0.1 1.2 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.1 0.3 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.1 0.2 GO:0071469 cellular response to alkaline pH(GO:0071469)
0.1 0.8 GO:0045793 positive regulation of cell size(GO:0045793)
0.1 0.2 GO:0098582 innate vocalization behavior(GO:0098582)
0.1 1.7 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.1 0.6 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.1 0.2 GO:1900276 regulation of proteinase activated receptor activity(GO:1900276) negative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900737)
0.1 0.9 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.1 1.6 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.1 0.2 GO:0060139 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139) apoptotic process involved in embryonic digit morphogenesis(GO:1902263)
0.0 0.4 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.0 0.7 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 1.0 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 1.3 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.0 0.3 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.7 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.2 GO:0030866 cortical cytoskeleton organization(GO:0030865) cortical actin cytoskeleton organization(GO:0030866)
0.0 5.1 GO:0006081 cellular aldehyde metabolic process(GO:0006081)
0.0 0.5 GO:0070307 lens fiber cell development(GO:0070307)
0.0 1.7 GO:0061641 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.5 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.0 0.7 GO:0048505 regulation of development, heterochronic(GO:0040034) regulation of timing of cell differentiation(GO:0048505)
0.0 0.1 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.0 0.6 GO:0010838 positive regulation of keratinocyte proliferation(GO:0010838)
0.0 0.9 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.9 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 1.0 GO:0048240 sperm capacitation(GO:0048240)
0.0 1.0 GO:0022011 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0 0.2 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.3 GO:0070842 aggresome assembly(GO:0070842)
0.0 0.2 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.0 0.5 GO:0036148 phosphatidylglycerol acyl-chain remodeling(GO:0036148)
0.0 0.8 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.0 0.1 GO:0050928 negative regulation of positive chemotaxis(GO:0050928)
0.0 0.5 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.3 GO:0019532 oxalate transport(GO:0019532)
0.0 2.7 GO:0070527 platelet aggregation(GO:0070527)
0.0 0.1 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.3 GO:0097152 mesenchymal cell apoptotic process(GO:0097152)
0.0 1.3 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.1 GO:0006581 acetylcholine catabolic process in synaptic cleft(GO:0001507) acetylcholine catabolic process(GO:0006581)
0.0 0.1 GO:0009258 10-formyltetrahydrofolate catabolic process(GO:0009258)
0.0 4.3 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 1.0 GO:0061014 positive regulation of mRNA catabolic process(GO:0061014)
0.0 0.8 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.0 0.5 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 0.9 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.6 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 0.3 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.3 GO:1904896 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.0 0.5 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 0.4 GO:0045109 intermediate filament organization(GO:0045109)
0.0 0.2 GO:0032526 response to retinoic acid(GO:0032526)
0.0 0.1 GO:0000432 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432)
0.0 0.3 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.0 1.2 GO:0009060 aerobic respiration(GO:0009060)
0.0 0.1 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.2 GO:0048711 positive regulation of astrocyte differentiation(GO:0048711)
0.0 0.1 GO:1902358 sulfate transmembrane transport(GO:1902358)
0.0 0.9 GO:0021762 substantia nigra development(GO:0021762)
0.0 0.3 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.0 4.8 GO:0031032 actomyosin structure organization(GO:0031032)
0.0 2.0 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 0.3 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.0 0.6 GO:0006735 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0 0.2 GO:0060009 Sertoli cell development(GO:0060009)
0.0 1.1 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.3 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.3 GO:0030336 negative regulation of cell migration(GO:0030336)
0.0 0.2 GO:0035372 protein localization to microtubule(GO:0035372)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0043257 laminin-8 complex(GO:0043257)
0.3 1.2 GO:0070288 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.3 2.4 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.2 0.7 GO:0031523 Myb complex(GO:0031523)
0.1 1.2 GO:0097165 nuclear stress granule(GO:0097165)
0.1 0.3 GO:0000815 ESCRT III complex(GO:0000815)
0.1 0.8 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 0.8 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.1 1.1 GO:0061689 tricellular tight junction(GO:0061689)
0.1 1.0 GO:0097524 sperm plasma membrane(GO:0097524)
0.1 2.6 GO:0043194 axon initial segment(GO:0043194)
0.1 3.1 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.1 1.1 GO:0033269 internode region of axon(GO:0033269)
0.1 1.3 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.1 0.7 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.1 0.7 GO:0098651 basement membrane collagen trimer(GO:0098651)
0.1 1.5 GO:0000346 transcription export complex(GO:0000346)
0.1 1.0 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.1 2.9 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 0.3 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.1 0.2 GO:0039714 viral factory(GO:0039713) cytoplasmic viral factory(GO:0039714) host cell viral assembly compartment(GO:0072517)
0.1 0.6 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.1 2.1 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.4 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.3 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.8 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 1.0 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.3 GO:1990037 Lewy body core(GO:1990037)
0.0 0.8 GO:0042555 MCM complex(GO:0042555)
0.0 1.7 GO:0000145 exocyst(GO:0000145)
0.0 1.3 GO:0044295 axonal growth cone(GO:0044295)
0.0 1.1 GO:0071565 nBAF complex(GO:0071565)
0.0 0.1 GO:0034677 integrin alpha7-beta1 complex(GO:0034677)
0.0 0.8 GO:0035102 PRC1 complex(GO:0035102)
0.0 1.8 GO:0035861 site of double-strand break(GO:0035861)
0.0 1.4 GO:0031312 extrinsic component of organelle membrane(GO:0031312)
0.0 0.4 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.6 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.3 GO:0030905 retromer, tubulation complex(GO:0030905)
0.0 0.3 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 3.9 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.1 GO:0036398 TCR signalosome(GO:0036398)
0.0 0.7 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.4 GO:0042641 actomyosin(GO:0042641)
0.0 0.6 GO:0005922 connexon complex(GO:0005922)
0.0 1.6 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.5 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.6 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 5.6 GO:0070382 exocytic vesicle(GO:0070382)
0.0 0.1 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.5 GO:0005795 Golgi stack(GO:0005795)
0.0 0.6 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 3.2 GO:0072562 blood microparticle(GO:0072562)
0.0 0.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.6 GO:0030137 COPI-coated vesicle(GO:0030137)
0.0 2.3 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.0 0.5 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.9 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.4 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 1.2 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 1.3 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.2 GO:0032426 stereocilium tip(GO:0032426)
0.0 1.0 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.0 0.6 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 6.4 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.5 2.7 GO:0031849 olfactory receptor binding(GO:0031849)
0.4 1.2 GO:0004756 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.4 1.4 GO:0004796 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.2 2.7 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.2 0.9 GO:0004113 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity(GO:0004113)
0.2 0.6 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.2 0.6 GO:0045142 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116) DNA/RNA helicase activity(GO:0033677) triplex DNA binding(GO:0045142)
0.2 0.5 GO:1904713 beta-catenin destruction complex binding(GO:1904713)
0.2 0.7 GO:0004356 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.2 1.3 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.2 1.0 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.2 1.0 GO:0047685 amine sulfotransferase activity(GO:0047685)
0.2 2.1 GO:0008199 ferric iron binding(GO:0008199)
0.2 1.5 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.2 1.8 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.1 1.6 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.1 2.2 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.1 3.8 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.1 3.5 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 5.2 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 2.1 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 0.4 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.1 0.7 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.1 1.6 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.1 1.0 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.1 1.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 0.9 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.1 1.5 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.1 0.3 GO:0001069 regulatory region RNA binding(GO:0001069)
0.1 0.6 GO:1903763 gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
0.1 0.7 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.1 0.6 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.1 0.4 GO:0005119 smoothened binding(GO:0005119)
0.1 1.0 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 1.9 GO:0051787 misfolded protein binding(GO:0051787)
0.1 3.5 GO:0003785 actin monomer binding(GO:0003785)
0.1 0.3 GO:1990460 leptin receptor binding(GO:1990460)
0.1 0.9 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 0.7 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.5 GO:0035005 lipid kinase activity(GO:0001727) 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.7 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 4.9 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 2.4 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 1.8 GO:0070410 co-SMAD binding(GO:0070410)
0.0 1.1 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.8 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.1 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.0 0.5 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.4 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 1.2 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.8 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.3 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.0 0.3 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 1.9 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.2 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.0 1.5 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.2 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 0.8 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 1.2 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.1 GO:0004803 transposase activity(GO:0004803)
0.0 0.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 2.1 GO:0097110 scaffold protein binding(GO:0097110)
0.0 1.8 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.1 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.0 0.4 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 0.1 GO:0015275 stretch-activated, cation-selective, calcium channel activity(GO:0015275)
0.0 0.6 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 4.7 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds(GO:0016810)
0.0 1.0 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 1.1 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.6 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.8 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.5 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.4 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.6 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 1.5 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 2.2 GO:0000149 SNARE binding(GO:0000149)
0.0 0.7 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.2 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.3 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.2 GO:0000182 rDNA binding(GO:0000182)
0.0 0.4 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 1.1 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.3 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.6 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.4 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 8.4 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 2.6 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 4.9 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 1.0 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 1.0 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 1.0 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 1.7 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 2.5 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.8 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 2.7 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 1.3 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 3.1 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 3.0 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 2.5 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 1.0 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.5 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.2 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.6 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 0.6 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.6 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.2 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.4 PID BMP PATHWAY BMP receptor signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 6.0 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.1 4.0 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 1.9 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.1 4.0 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.1 0.7 REACTOME OPSINS Genes involved in Opsins
0.1 2.9 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.1 1.6 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 0.6 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 2.2 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 1.0 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 1.1 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.8 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 1.8 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 5.7 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 2.4 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 1.0 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.8 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.6 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.7 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.5 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.6 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 1.8 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 2.0 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 1.2 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.0 1.6 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.9 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 2.8 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 1.4 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 1.1 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.2 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.8 REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT Genes involved in p53-Independent G1/S DNA damage checkpoint
0.0 1.7 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 1.1 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.7 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction