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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for SOX7

Z-value: 0.58

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Transcription factors associated with SOX7

Gene Symbol Gene ID Gene Info
ENSG00000171056.6 SRY-box transcription factor 7
ENSG00000258724.1 SRY-box transcription factor 7

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SOX7hg19_v2_chr8_-_10588010_10588030-0.843.3e-06Click!

Activity profile of SOX7 motif

Sorted Z-values of SOX7 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_58027138 2.56 ENST00000341156.4
beta-1,4-N-acetyl-galactosaminyl transferase 1
chr10_+_5005445 2.51 ENST00000380872.4
aldo-keto reductase family 1, member C1
chr10_-_5046042 2.19 ENST00000421196.3
ENST00000455190.1
aldo-keto reductase family 1, member C2
chr2_-_190445499 1.66 ENST00000261024.2
solute carrier family 40 (iron-regulated transporter), member 1
chr8_-_19459993 1.60 ENST00000454498.2
ENST00000520003.1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr12_-_90049828 1.40 ENST00000261173.2
ENST00000348959.3
ATPase, Ca++ transporting, plasma membrane 1
chr1_+_199996733 1.40 ENST00000236914.3
nuclear receptor subfamily 5, group A, member 2
chr12_-_90049878 1.16 ENST00000359142.3
ATPase, Ca++ transporting, plasma membrane 1
chrY_+_14813160 1.13 ENST00000338981.3
ubiquitin specific peptidase 9, Y-linked
chr12_-_57443886 1.01 ENST00000300119.3
myosin IA
chr1_+_10509971 0.95 ENST00000320498.4
cortistatin
chr5_-_95158644 0.84 ENST00000237858.6
glutaredoxin (thioltransferase)
chr1_+_156698743 0.82 ENST00000524343.1
ribosomal RNA adenine dimethylase domain containing 1
chr11_+_7618413 0.81 ENST00000528883.1
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr9_-_70465758 0.74 ENST00000489273.1
COBW domain containing 5
chr5_-_95158375 0.71 ENST00000512469.2
ENST00000379979.4
ENST00000505427.1
ENST00000508780.1
glutaredoxin (thioltransferase)
chr11_-_62474803 0.70 ENST00000533982.1
ENST00000360796.5
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr1_+_156698708 0.67 ENST00000519086.1
ribosomal RNA adenine dimethylase domain containing 1
chr12_+_64173583 0.65 ENST00000261234.6
transmembrane protein 5
chr16_-_279405 0.62 ENST00000430864.1
ENST00000293872.8
ENST00000337351.4
ENST00000397783.1
LUC7-like (S. cerevisiae)
chr8_-_102803163 0.62 ENST00000523645.1
ENST00000520346.1
ENST00000220931.6
ENST00000522448.1
ENST00000522951.1
ENST00000522252.1
ENST00000519098.1
neurocalcin delta
chr19_-_5784610 0.61 ENST00000390672.2
ENST00000419421.2
proline rich 22
chr16_+_28303804 0.55 ENST00000341901.4
SH3 domain binding kinase 1
chr2_-_68547019 0.54 ENST00000409862.1
cannabinoid receptor interacting protein 1
chr15_+_75639372 0.51 ENST00000566313.1
ENST00000568059.1
ENST00000568881.1
nei endonuclease VIII-like 1 (E. coli)
chr2_+_179317994 0.51 ENST00000375129.4
deafness, autosomal recessive 59
chr3_-_123411191 0.50 ENST00000354792.5
ENST00000508240.1
myosin light chain kinase
chr16_-_28303360 0.49 ENST00000501520.1
RP11-57A19.2
chr15_+_66585950 0.49 ENST00000525109.1
DIS3 mitotic control homolog (S. cerevisiae)-like
chr8_+_77593448 0.43 ENST00000521891.2
zinc finger homeobox 4
chr17_-_66951382 0.39 ENST00000586539.1
ATP-binding cassette, sub-family A (ABC1), member 8
chr12_-_123728548 0.38 ENST00000545406.1
M-phase phosphoprotein 9
chr1_+_223101757 0.37 ENST00000284476.6
dispatched homolog 1 (Drosophila)
chr9_-_37592561 0.35 ENST00000544379.1
ENST00000377773.5
ENST00000401811.3
ENST00000321301.6
translocase of outer mitochondrial membrane 5 homolog (yeast)
chr14_+_101361107 0.31 ENST00000553584.1
ENST00000554852.1
maternally expressed 8 (non-protein coding)
chr17_-_66951474 0.26 ENST00000269080.2
ATP-binding cassette, sub-family A (ABC1), member 8
chr17_-_56082455 0.26 ENST00000578794.1
Uncharacterized protein
chr21_-_15918618 0.24 ENST00000400564.1
ENST00000400566.1
SAM domain, SH3 domain and nuclear localization signals 1
chr6_-_111804905 0.24 ENST00000358835.3
ENST00000435970.1
REV3-like, polymerase (DNA directed), zeta, catalytic subunit
chr2_-_152118276 0.23 ENST00000409092.1
RNA binding motif protein 43
chr5_+_161494770 0.23 ENST00000414552.2
ENST00000361925.4
gamma-aminobutyric acid (GABA) A receptor, gamma 2
chrX_+_69353284 0.22 ENST00000342206.6
ENST00000356413.4
immunoglobulin (CD79A) binding protein 1
chr6_-_86303833 0.20 ENST00000505648.1
sorting nexin 14
chr4_-_177190364 0.19 ENST00000296525.3
ankyrin repeat and SOCS box containing 5
chr17_-_28661065 0.19 ENST00000328886.4
ENST00000538566.2
transmembrane and immunoglobulin domain containing 1
chr12_-_57328187 0.18 ENST00000293502.1
short chain dehydrogenase/reductase family 9C, member 7
chr19_-_38916802 0.18 ENST00000587738.1
RAS guanyl releasing protein 4
chr2_-_166930131 0.18 ENST00000303395.4
ENST00000409050.1
ENST00000423058.2
ENST00000375405.3
sodium channel, voltage-gated, type I, alpha subunit
chr16_-_21442874 0.17 ENST00000534903.1
nuclear pore complex interacting protein family, member B3
chr10_-_17243579 0.16 ENST00000525762.1
ENST00000412821.3
ENST00000351358.4
ENST00000377766.5
ENST00000358282.7
ENST00000488990.1
ENST00000377799.3
tRNA aspartic acid methyltransferase 1
chr17_-_39623681 0.16 ENST00000225899.3
keratin 32
chr21_+_34144411 0.16 ENST00000382375.4
ENST00000453404.1
ENST00000382378.1
ENST00000477513.1
chromosome 21 open reading frame 49
chr6_-_46048116 0.15 ENST00000185206.6
chloride intracellular channel 5
chr2_+_3705785 0.15 ENST00000252505.3
allantoicase
chr5_-_176778803 0.14 ENST00000303127.7
lectin, mannose-binding 2
chr6_+_168434678 0.13 ENST00000496008.1
kinesin family member 25
chr6_+_150690133 0.12 ENST00000392255.3
ENST00000500320.3
iodotyrosine deiodinase
chr6_+_80129989 0.12 ENST00000429444.1
RP1-232L24.3
chr19_-_38916822 0.11 ENST00000586305.1
RAS guanyl releasing protein 4
chr5_+_175511859 0.11 ENST00000503724.2
ENST00000253490.4
family with sequence similarity 153, member B
chr6_+_131894284 0.11 ENST00000368087.3
ENST00000356962.2
arginase 1
chr11_+_3011093 0.11 ENST00000332881.2
HCG1782999; PRO0943; Uncharacterized protein
chr16_+_22518495 0.11 ENST00000541154.1
nuclear pore complex interacting protein family, member B5
chr14_+_50291993 0.10 ENST00000595378.1
HCG1786899; PRO2610; Uncharacterized protein
chr17_+_80858418 0.10 ENST00000574422.1
tubulin folding cofactor D
chr8_+_12803176 0.09 ENST00000524591.2
KIAA1456
chr12_-_39734783 0.08 ENST00000552961.1
kinesin family member 21A
chr6_+_29555683 0.08 ENST00000383640.2
olfactory receptor, family 2, subfamily H, member 2
chr6_+_150690028 0.08 ENST00000229447.5
ENST00000344419.3
iodotyrosine deiodinase
chr1_+_100598742 0.07 ENST00000370139.1
tRNA methyltransferase 13 homolog (S. cerevisiae)
chr4_-_39034542 0.07 ENST00000344606.6
transmembrane protein 156
chr3_-_122694215 0.07 ENST00000449546.1
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B
chr6_+_150690089 0.07 ENST00000392256.2
iodotyrosine deiodinase
chr19_+_37837218 0.07 ENST00000591134.1
HKR1, GLI-Kruppel zinc finger family member
chr1_+_158901329 0.04 ENST00000368140.1
ENST00000368138.3
ENST00000392254.2
ENST00000392252.3
ENST00000368135.4
pyrin and HIN domain family, member 1
chr14_-_31856397 0.04 ENST00000538864.2
ENST00000550366.1
HEAT repeat containing 5A
chr15_+_59439899 0.03 ENST00000599727.1
C15ORF31
chr15_+_63414760 0.03 ENST00000557972.1
lactamase, beta
chr9_+_105757590 0.03 ENST00000374798.3
ENST00000487798.1
cylicin, basic protein of sperm head cytoskeleton 2

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX7

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 4.7 GO:0009753 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.6 1.7 GO:1903988 spleen trabecula formation(GO:0060345) iron cation export(GO:1903414) ferrous iron export(GO:1903988)
0.3 2.6 GO:1990034 cellular response to corticosterone stimulus(GO:0071386) calcium ion export from cell(GO:1990034)
0.2 2.6 GO:0030259 lipid glycosylation(GO:0030259)
0.2 1.4 GO:0061113 pancreas morphogenesis(GO:0061113)
0.2 1.6 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.1 0.5 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 1.5 GO:0031167 rRNA methylation(GO:0031167)
0.1 1.6 GO:0045838 positive regulation of membrane potential(GO:0045838)
0.0 1.0 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 0.1 GO:0046603 negative regulation of mitotic centrosome separation(GO:0046603)
0.0 0.7 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.7 GO:0042908 xenobiotic transport(GO:0042908)
0.0 0.2 GO:0043605 cellular amide catabolic process(GO:0043605)
0.0 0.5 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.0 1.0 GO:0030033 microvillus assembly(GO:0030033)
0.0 0.1 GO:0043091 L-arginine import(GO:0043091) arginine import(GO:0090467)
0.0 0.7 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.3 GO:0006570 tyrosine metabolic process(GO:0006570)
0.0 0.5 GO:0016075 rRNA catabolic process(GO:0016075)
0.0 0.4 GO:0060539 diaphragm development(GO:0060539)
0.0 0.2 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.0 0.2 GO:0071420 cellular response to histamine(GO:0071420)
0.0 0.6 GO:0006376 mRNA splice site selection(GO:0006376)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0071821 FANCM-MHF complex(GO:0071821)
0.1 2.6 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 4.2 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.2 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.6 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.4 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.5 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.5 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 1.0 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.2 GO:0032590 dendrite membrane(GO:0032590)
0.0 0.0 GO:0033011 perinuclear theca(GO:0033011)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 4.7 GO:0047086 phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086)
0.6 1.7 GO:0097689 iron channel activity(GO:0097689)
0.5 2.6 GO:0003947 (N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity(GO:0003947)
0.2 1.5 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.2 1.6 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
0.1 1.6 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.1 0.6 GO:0050733 RS domain binding(GO:0050733)
0.1 2.6 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 0.7 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.0 0.5 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.3 GO:0004447 iodide peroxidase activity(GO:0004447)
0.0 1.0 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.2 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.0 1.1 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.2 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 0.4 GO:0015197 peptide transporter activity(GO:0015197)
0.0 0.5 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0 0.3 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.6 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 1.4 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 0.1 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.6 PID CMYB PATHWAY C-MYB transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.6 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 1.6 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 1.7 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 1.4 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.6 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.7 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.3 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones