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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for SOX8

Z-value: 0.38

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Transcription factors associated with SOX8

Gene Symbol Gene ID Gene Info
SOX8
ENSG00000005513.9 SRY-box transcription factor 8

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SOX8hg19_v2_chr16_+_1031762_10318080.292.1e-01Click!

Activity profile of SOX8 motif

Sorted Z-values of SOX8 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr14_+_75745477 1.22 ENST00000303562.4
ENST00000554617.1
ENST00000554212.1
ENST00000535987.1
ENST00000555242.1
FOS
FBJ murine osteosarcoma viral oncogene homolog
chr1_+_153330322 1.10 ENST00000368738.3
S100A9
S100 calcium binding protein A9
chr4_+_155484155 0.87 ENST00000509493.1
FGB
fibrinogen beta chain
chr4_+_155484103 0.83 ENST00000302068.4
FGB
fibrinogen beta chain
chr18_+_61442629 0.71 ENST00000398019.2
ENST00000540675.1
SERPINB7
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr14_+_95078714 0.54 ENST00000393078.3
ENST00000393080.4
ENST00000467132.1
SERPINA3
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
chr12_-_10007448 0.52 ENST00000538152.1
CLEC2B
C-type lectin domain family 2, member B
chr12_-_8693469 0.48 ENST00000545274.1
ENST00000446457.2
CLEC4E
C-type lectin domain family 4, member E
chr2_-_25451065 0.36 ENST00000606328.1
RP11-458N5.1
RP11-458N5.1
chr20_+_48807351 0.35 ENST00000303004.3
CEBPB
CCAAT/enhancer binding protein (C/EBP), beta
chr19_+_1269324 0.35 ENST00000589710.1
ENST00000588230.1
ENST00000413636.2
ENST00000586472.1
ENST00000589686.1
ENST00000444172.2
ENST00000587323.1
ENST00000320936.5
ENST00000587896.1
ENST00000589235.1
ENST00000591659.1
CIRBP
cold inducible RNA binding protein
chr10_+_7745232 0.35 ENST00000358415.4
ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr21_-_47352477 0.33 ENST00000593412.1
PRED62
Uncharacterized protein
chr14_+_96722152 0.32 ENST00000216629.6
BDKRB1
bradykinin receptor B1
chr1_+_8378140 0.30 ENST00000377479.2
SLC45A1
solute carrier family 45, member 1
chr2_+_102615416 0.29 ENST00000393414.2
IL1R2
interleukin 1 receptor, type II
chr12_-_8693539 0.28 ENST00000299663.3
CLEC4E
C-type lectin domain family 4, member E
chr4_-_75024085 0.28 ENST00000600169.1
AC093677.1
Uncharacterized protein
chr3_-_49459878 0.28 ENST00000546031.1
ENST00000458307.2
ENST00000430521.1
AMT
aminomethyltransferase
chr10_-_101825151 0.27 ENST00000441382.1
CPN1
carboxypeptidase N, polypeptide 1
chr1_-_153029980 0.26 ENST00000392653.2
SPRR2A
small proline-rich protein 2A
chr6_-_117150198 0.26 ENST00000310357.3
ENST00000368549.3
ENST00000530250.1
GPRC6A
G protein-coupled receptor, family C, group 6, member A
chr4_-_47983519 0.26 ENST00000358519.4
ENST00000544810.1
ENST00000402813.3
CNGA1
cyclic nucleotide gated channel alpha 1
chr19_+_39903185 0.26 ENST00000409794.3
PLEKHG2
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chr9_-_130661916 0.25 ENST00000373142.1
ENST00000373146.1
ENST00000373144.3
ST6GALNAC6
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr16_+_30075783 0.24 ENST00000412304.2
ALDOA
aldolase A, fructose-bisphosphate
chr11_-_125366089 0.24 ENST00000366139.3
ENST00000278919.3
FEZ1
fasciculation and elongation protein zeta 1 (zygin I)
chr3_-_49851313 0.23 ENST00000333486.3
UBA7
ubiquitin-like modifier activating enzyme 7
chr22_+_24236191 0.23 ENST00000215754.7
MIF
macrophage migration inhibitory factor (glycosylation-inhibiting factor)
chr19_-_45681482 0.22 ENST00000592647.1
ENST00000006275.4
ENST00000588062.1
ENST00000585934.1
TRAPPC6A
trafficking protein particle complex 6A
chr3_-_49459865 0.22 ENST00000427987.1
AMT
aminomethyltransferase
chr6_+_31707725 0.22 ENST00000375755.3
ENST00000375742.3
ENST00000375750.3
ENST00000425703.1
ENST00000534153.4
ENST00000375703.3
ENST00000375740.3
MSH5
mutS homolog 5
chr17_-_7145475 0.21 ENST00000571129.1
ENST00000571253.1
ENST00000573928.1
GABARAP
GABA(A) receptor-associated protein
chr17_+_2240916 0.21 ENST00000574563.1
SGSM2
small G protein signaling modulator 2
chr1_-_38512450 0.20 ENST00000373012.2
POU3F1
POU class 3 homeobox 1
chr12_+_113354341 0.20 ENST00000553152.1
OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr16_+_30075595 0.20 ENST00000563060.2
ALDOA
aldolase A, fructose-bisphosphate
chr16_+_30076052 0.20 ENST00000563987.1
ALDOA
aldolase A, fructose-bisphosphate
chr18_-_73967160 0.19 ENST00000579714.1
RP11-94B19.7
RP11-94B19.7
chr16_-_90096309 0.19 ENST00000408886.2
C16orf3
chromosome 16 open reading frame 3
chr16_+_29690358 0.19 ENST00000395384.4
ENST00000562473.1
QPRT
quinolinate phosphoribosyltransferase
chr4_+_22999152 0.18 ENST00000511453.1
RP11-412P11.1
RP11-412P11.1
chr3_-_54962100 0.18 ENST00000273286.5
LRTM1
leucine-rich repeats and transmembrane domains 1
chr1_+_26496362 0.18 ENST00000374266.5
ENST00000270812.5
ZNF593
zinc finger protein 593
chr2_-_187367356 0.17 ENST00000595956.1
AC018867.2
AC018867.2
chr16_-_28503357 0.17 ENST00000333496.9
ENST00000561505.1
ENST00000567963.1
ENST00000354630.5
ENST00000355477.5
ENST00000357076.5
ENST00000565688.1
ENST00000359984.7
CLN3
ceroid-lipofuscinosis, neuronal 3
chr2_+_97203082 0.17 ENST00000454558.2
ARID5A
AT rich interactive domain 5A (MRF1-like)
chr5_-_138534071 0.17 ENST00000394817.2
SIL1
SIL1 nucleotide exchange factor
chr1_-_238649319 0.17 ENST00000400946.2
RP11-371I1.2
long intergenic non-protein coding RNA 1139
chr20_-_5426380 0.17 ENST00000609252.1
ENST00000422352.1
LINC00658
long intergenic non-protein coding RNA 658
chr1_+_12806141 0.17 ENST00000288048.5
C1orf158
chromosome 1 open reading frame 158
chr17_-_27230035 0.17 ENST00000378895.4
ENST00000394901.3
DHRS13
dehydrogenase/reductase (SDR family) member 13
chr12_-_123187890 0.17 ENST00000328880.5
HCAR2
hydroxycarboxylic acid receptor 2
chr6_+_37012607 0.17 ENST00000423336.1
COX6A1P2
cytochrome c oxidase subunit VIa polypeptide 1 pseudogene 2
chr16_+_57392684 0.17 ENST00000219235.4
CCL22
chemokine (C-C motif) ligand 22
chr17_-_7387524 0.17 ENST00000311403.4
ZBTB4
zinc finger and BTB domain containing 4
chr22_-_50708781 0.16 ENST00000449719.2
ENST00000330651.6
MAPK11
mitogen-activated protein kinase 11
chr1_+_152956549 0.16 ENST00000307122.2
SPRR1A
small proline-rich protein 1A
chr11_+_128563652 0.16 ENST00000527786.2
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr11_+_57435219 0.16 ENST00000527985.1
ENST00000287169.3
ZDHHC5
zinc finger, DHHC-type containing 5
chr16_+_30075463 0.16 ENST00000562168.1
ENST00000569545.1
ALDOA
aldolase A, fructose-bisphosphate
chr14_+_96722539 0.16 ENST00000553356.1
BDKRB1
bradykinin receptor B1
chr18_-_77711625 0.16 ENST00000357575.4
ENST00000590381.1
ENST00000397778.2
PQLC1
PQ loop repeat containing 1
chr19_-_21950332 0.16 ENST00000598026.1
ZNF100
zinc finger protein 100
chr3_-_187455680 0.15 ENST00000438077.1
BCL6
B-cell CLL/lymphoma 6
chr5_+_140792614 0.15 ENST00000398610.2
PCDHGA10
protocadherin gamma subfamily A, 10
chr16_-_122619 0.15 ENST00000262316.6
RHBDF1
rhomboid 5 homolog 1 (Drosophila)
chr22_-_30722912 0.15 ENST00000215790.7
TBC1D10A
TBC1 domain family, member 10A
chr1_-_26197744 0.15 ENST00000374296.3
PAQR7
progestin and adipoQ receptor family member VII
chr11_+_18154059 0.14 ENST00000531264.1
MRGPRX3
MAS-related GPR, member X3
chr17_-_34207295 0.14 ENST00000463941.1
ENST00000293272.3
CCL5
chemokine (C-C motif) ligand 5
chr5_+_140602904 0.14 ENST00000515856.2
ENST00000239449.4
PCDHB14
protocadherin beta 14
chr2_+_173792893 0.14 ENST00000535187.1
RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr2_-_228497888 0.14 ENST00000264387.4
ENST00000409066.1
C2orf83
chromosome 2 open reading frame 83
chr6_-_150217195 0.14 ENST00000532335.1
RAET1E
retinoic acid early transcript 1E
chr6_-_49712147 0.13 ENST00000433368.2
ENST00000354620.4
CRISP3
cysteine-rich secretory protein 3
chr2_+_13677795 0.13 ENST00000434509.1
AC092635.1
AC092635.1
chr2_-_36779411 0.13 ENST00000406220.1
AC007401.2
Uncharacterized protein
chr22_-_30722866 0.13 ENST00000403477.3
TBC1D10A
TBC1 domain family, member 10A
chr19_+_18794470 0.13 ENST00000321949.8
ENST00000338797.6
CRTC1
CREB regulated transcription coactivator 1
chr11_-_58035732 0.13 ENST00000395079.2
OR10W1
olfactory receptor, family 10, subfamily W, member 1
chr8_-_11873043 0.13 ENST00000527396.1
RP11-481A20.11
Protein LOC101060662
chr2_+_166326157 0.13 ENST00000421875.1
ENST00000314499.7
ENST00000409664.1
CSRNP3
cysteine-serine-rich nuclear protein 3
chr22_-_50523688 0.13 ENST00000450140.2
MLC1
megalencephalic leukoencephalopathy with subcortical cysts 1
chr15_+_45926919 0.13 ENST00000561735.1
ENST00000260324.7
SQRDL
sulfide quinone reductase-like (yeast)
chr17_-_66951474 0.13 ENST00000269080.2
ABCA8
ATP-binding cassette, sub-family A (ABC1), member 8
chr9_-_95244781 0.12 ENST00000375544.3
ENST00000375543.1
ENST00000395538.3
ENST00000450139.2
ASPN
asporin
chr3_-_100558953 0.12 ENST00000533795.1
ABI3BP
ABI family, member 3 (NESH) binding protein
chr2_-_190448118 0.12 ENST00000440626.1
SLC40A1
solute carrier family 40 (iron-regulated transporter), member 1
chr15_+_25101698 0.12 ENST00000400097.1
SNRPN
small nuclear ribonucleoprotein polypeptide N
chr20_+_32399093 0.12 ENST00000217402.2
CHMP4B
charged multivesicular body protein 4B
chr14_-_69263043 0.12 ENST00000408913.2
ZFP36L1
ZFP36 ring finger protein-like 1
chr15_+_43985084 0.12 ENST00000434505.1
ENST00000411750.1
CKMT1A
creatine kinase, mitochondrial 1A
chr1_+_110577229 0.11 ENST00000369795.3
ENST00000369794.2
STRIP1
striatin interacting protein 1
chr14_-_92247032 0.11 ENST00000556661.1
ENST00000553676.1
ENST00000554560.1
CATSPERB
catsper channel auxiliary subunit beta
chr19_-_37663332 0.11 ENST00000392157.2
ZNF585A
zinc finger protein 585A
chr6_-_159421198 0.11 ENST00000252655.1
ENST00000297262.3
ENST00000367069.2
RSPH3
radial spoke 3 homolog (Chlamydomonas)
chr18_-_3845293 0.11 ENST00000400145.2
DLGAP1
discs, large (Drosophila) homolog-associated protein 1
chr21_-_43735628 0.11 ENST00000291525.10
ENST00000518498.1
TFF3
trefoil factor 3 (intestinal)
chr16_+_21244986 0.11 ENST00000311620.5
ANKS4B
ankyrin repeat and sterile alpha motif domain containing 4B
chr10_-_1779663 0.11 ENST00000381312.1
ADARB2
adenosine deaminase, RNA-specific, B2 (non-functional)
chr12_-_123201337 0.11 ENST00000528880.2
HCAR3
hydroxycarboxylic acid receptor 3
chr1_-_205053645 0.11 ENST00000367167.3
TMEM81
transmembrane protein 81
chr3_+_186288454 0.11 ENST00000265028.3
DNAJB11
DnaJ (Hsp40) homolog, subfamily B, member 11
chr8_+_87111059 0.11 ENST00000285393.3
ATP6V0D2
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2
chr5_+_140800638 0.11 ENST00000398587.2
ENST00000518882.1
PCDHGA11
protocadherin gamma subfamily A, 11
chr4_+_156680153 0.11 ENST00000502959.1
ENST00000505764.1
ENST00000507146.1
ENST00000264424.8
ENST00000503520.1
GUCY1B3
guanylate cyclase 1, soluble, beta 3
chr9_-_139891165 0.11 ENST00000494426.1
CLIC3
chloride intracellular channel 3
chr12_+_133066137 0.11 ENST00000434748.2
FBRSL1
fibrosin-like 1
chr1_+_87012753 0.11 ENST00000370563.3
CLCA4
chloride channel accessory 4
chr1_+_38512799 0.11 ENST00000432922.1
ENST00000428151.1
RP5-884C9.2
RP5-884C9.2
chr5_-_160973649 0.11 ENST00000393959.1
ENST00000517547.1
GABRB2
gamma-aminobutyric acid (GABA) A receptor, beta 2
chr6_-_134638767 0.11 ENST00000524929.1
SGK1
serum/glucocorticoid regulated kinase 1
chr12_+_56325812 0.11 ENST00000394147.1
ENST00000551156.1
ENST00000553783.1
ENST00000557080.1
ENST00000432422.3
ENST00000556001.1
DGKA
diacylglycerol kinase, alpha 80kDa
chr8_+_52730143 0.11 ENST00000415643.1
AC090186.1
Uncharacterized protein
chr12_-_71551652 0.10 ENST00000546561.1
TSPAN8
tetraspanin 8
chr2_+_135596106 0.10 ENST00000356140.5
ACMSD
aminocarboxymuconate semialdehyde decarboxylase
chr12_-_10282836 0.10 ENST00000304084.8
ENST00000353231.5
ENST00000525605.1
CLEC7A
C-type lectin domain family 7, member A
chr3_+_173116225 0.10 ENST00000457714.1
NLGN1
neuroligin 1
chr15_+_43885252 0.10 ENST00000453782.1
ENST00000300283.6
ENST00000437924.1
ENST00000450086.2
CKMT1B
creatine kinase, mitochondrial 1B
chr10_+_103986085 0.10 ENST00000370005.3
ELOVL3
ELOVL fatty acid elongase 3
chr2_+_204801471 0.10 ENST00000316386.6
ENST00000435193.1
ICOS
inducible T-cell co-stimulator
chr1_+_70876926 0.10 ENST00000370938.3
ENST00000346806.2
CTH
cystathionase (cystathionine gamma-lyase)
chr10_-_131762105 0.10 ENST00000368648.3
ENST00000355311.5
EBF3
early B-cell factor 3
chr7_+_6714599 0.10 ENST00000328239.7
ENST00000542006.1
AC073343.1
Uncharacterized protein
chr5_-_160279207 0.10 ENST00000327245.5
ATP10B
ATPase, class V, type 10B
chr1_-_248802559 0.10 ENST00000317450.3
OR2T35
olfactory receptor, family 2, subfamily T, member 35
chr12_-_57443886 0.10 ENST00000300119.3
MYO1A
myosin IA
chr7_+_80275752 0.10 ENST00000419819.2
CD36
CD36 molecule (thrombospondin receptor)
chr1_+_161475208 0.10 ENST00000367972.4
ENST00000271450.6
FCGR2A
Fc fragment of IgG, low affinity IIa, receptor (CD32)
chr4_-_140544386 0.10 ENST00000561977.1
RP11-308D13.3
RP11-308D13.3
chr11_+_43702322 0.10 ENST00000395700.4
HSD17B12
hydroxysteroid (17-beta) dehydrogenase 12
chr3_+_185080908 0.09 ENST00000265026.3
MAP3K13
mitogen-activated protein kinase kinase kinase 13
chr7_+_6713376 0.09 ENST00000399484.3
ENST00000544825.1
ENST00000401847.1
AC073343.1
Uncharacterized protein
chr1_-_197036364 0.09 ENST00000367412.1
F13B
coagulation factor XIII, B polypeptide
chr17_-_73663245 0.09 ENST00000584999.1
ENST00000317905.5
ENST00000420326.2
ENST00000340830.5
RECQL5
RecQ protein-like 5
chr21_-_19858196 0.09 ENST00000422787.1
TMPRSS15
transmembrane protease, serine 15
chr5_+_75904950 0.09 ENST00000502745.1
IQGAP2
IQ motif containing GTPase activating protein 2
chr2_-_219151487 0.09 ENST00000444881.1
TMBIM1
transmembrane BAX inhibitor motif containing 1
chr1_-_9811600 0.09 ENST00000435891.1
CLSTN1
calsyntenin 1
chr18_-_11148587 0.09 ENST00000302079.6
ENST00000580640.1
ENST00000503781.3
PIEZO2
piezo-type mechanosensitive ion channel component 2
chr4_-_16085657 0.09 ENST00000543373.1
PROM1
prominin 1
chr20_+_32250079 0.09 ENST00000375222.3
C20orf144
chromosome 20 open reading frame 144
chr1_+_200993071 0.09 ENST00000446333.1
ENST00000458003.1
RP11-168O16.1
RP11-168O16.1
chr20_-_1472029 0.09 ENST00000359801.3
SIRPB2
signal-regulatory protein beta 2
chr4_-_186578674 0.09 ENST00000438278.1
SORBS2
sorbin and SH3 domain containing 2
chr17_-_37123646 0.09 ENST00000378079.2
FBXO47
F-box protein 47
chr10_-_49482907 0.09 ENST00000374201.3
ENST00000407470.4
FRMPD2
FERM and PDZ domain containing 2
chr3_+_577893 0.09 ENST00000420823.1
ENST00000442809.1
AC090044.1
AC090044.1
chr4_-_69111401 0.09 ENST00000332644.5
TMPRSS11B
transmembrane protease, serine 11B
chr12_+_14927270 0.09 ENST00000544848.1
H2AFJ
H2A histone family, member J
chr4_-_83765613 0.09 ENST00000503937.1
SEC31A
SEC31 homolog A (S. cerevisiae)
chr11_-_121986923 0.09 ENST00000560104.1
BLID
BH3-like motif containing, cell death inducer
chr19_+_36606933 0.09 ENST00000586868.1
TBCB
tubulin folding cofactor B
chr11_+_125774362 0.09 ENST00000530414.1
ENST00000530129.2
DDX25
DEAD (Asp-Glu-Ala-Asp) box helicase 25
chr12_+_122242597 0.09 ENST00000267197.5
SETD1B
SET domain containing 1B
chr10_+_53806501 0.09 ENST00000373975.2
PRKG1
protein kinase, cGMP-dependent, type I
chr1_+_158901329 0.08 ENST00000368140.1
ENST00000368138.3
ENST00000392254.2
ENST00000392252.3
ENST00000368135.4
PYHIN1
pyrin and HIN domain family, member 1
chr11_+_128563948 0.08 ENST00000534087.2
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr19_-_49567124 0.08 ENST00000301411.3
NTF4
neurotrophin 4
chr5_+_140753444 0.08 ENST00000517434.1
PCDHGA6
protocadherin gamma subfamily A, 6
chr1_+_81106951 0.08 ENST00000443565.1
RP5-887A10.1
RP5-887A10.1
chr10_-_4285923 0.08 ENST00000418372.1
ENST00000608792.1
LINC00702
long intergenic non-protein coding RNA 702
chr16_+_82068830 0.08 ENST00000199936.4
HSD17B2
hydroxysteroid (17-beta) dehydrogenase 2
chr19_+_45681997 0.08 ENST00000433642.2
BLOC1S3
biogenesis of lysosomal organelles complex-1, subunit 3
chr5_-_179499108 0.08 ENST00000521389.1
RNF130
ring finger protein 130
chr1_-_116383738 0.08 ENST00000320238.3
NHLH2
nescient helix loop helix 2
chr6_-_76072719 0.08 ENST00000370020.1
FILIP1
filamin A interacting protein 1
chr4_-_144826682 0.08 ENST00000358615.4
ENST00000437468.2
GYPE
glycophorin E (MNS blood group)
chr3_+_14693247 0.08 ENST00000383794.3
ENST00000303688.7
CCDC174
coiled-coil domain containing 174
chr12_+_48876275 0.08 ENST00000314014.2
C12orf54
chromosome 12 open reading frame 54
chr8_-_135522425 0.08 ENST00000521673.1
ZFAT
zinc finger and AT hook domain containing
chr1_-_145715565 0.08 ENST00000369288.2
ENST00000369290.1
ENST00000401557.3
CD160
CD160 molecule
chr6_-_49712123 0.08 ENST00000263045.4
CRISP3
cysteine-rich secretory protein 3
chr16_+_57769635 0.08 ENST00000379661.3
ENST00000562592.1
ENST00000566726.1
KATNB1
katanin p80 (WD repeat containing) subunit B 1
chr11_-_83878041 0.08 ENST00000398299.1
DLG2
discs, large homolog 2 (Drosophila)
chr6_-_52668605 0.08 ENST00000334575.5
GSTA1
glutathione S-transferase alpha 1
chr3_-_129147432 0.08 ENST00000503957.1
ENST00000505956.1
ENST00000326085.3
EFCAB12
EF-hand calcium binding domain 12
chr2_-_239140011 0.08 ENST00000409376.1
ENST00000409070.1
ENST00000409942.1
AC016757.3
Protein LOC151174
chrX_+_41548220 0.08 ENST00000378142.4
GPR34
G protein-coupled receptor 34
chr2_-_170550877 0.07 ENST00000447353.1
CCDC173
coiled-coil domain containing 173
chr10_-_4285835 0.07 ENST00000454470.1
LINC00702
long intergenic non-protein coding RNA 702
chr4_+_156680143 0.07 ENST00000505154.1
GUCY1B3
guanylate cyclase 1, soluble, beta 3
chr7_-_92855762 0.07 ENST00000453812.2
ENST00000394468.2
HEPACAM2
HEPACAM family member 2
chr22_-_50523760 0.07 ENST00000395876.2
MLC1
megalencephalic leukoencephalopathy with subcortical cysts 1
chr2_+_113816215 0.07 ENST00000346807.3
IL36RN
interleukin 36 receptor antagonist
chr9_+_99690592 0.07 ENST00000354649.3
NUTM2G
NUT family member 2G
chr4_-_10686475 0.07 ENST00000226951.6
CLNK
cytokine-dependent hematopoietic cell linker
chr22_-_30642728 0.07 ENST00000403987.3
LIF
leukemia inhibitory factor
chr9_-_16276311 0.07 ENST00000380685.1
C9orf92
chromosome 9 open reading frame 92
chr17_-_66951382 0.07 ENST00000586539.1
ABCA8
ATP-binding cassette, sub-family A (ABC1), member 8
chr17_+_7387677 0.07 ENST00000322644.6
POLR2A
polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
chr3_-_186288097 0.07 ENST00000446782.1
TBCCD1
TBCC domain containing 1
chr13_-_47012325 0.07 ENST00000409879.2
KIAA0226L
KIAA0226-like
chr14_-_21562671 0.07 ENST00000554923.1
ZNF219
zinc finger protein 219
chr18_+_32173276 0.07 ENST00000591816.1
ENST00000588125.1
ENST00000598334.1
ENST00000588684.1
ENST00000554864.3
ENST00000399121.5
ENST00000595022.1
ENST00000269190.7
ENST00000399097.3
DTNA
dystrobrevin, alpha
chr6_-_22297730 0.07 ENST00000306482.1
PRL
prolactin
chr3_+_173302222 0.07 ENST00000361589.4
NLGN1
neuroligin 1
chr22_-_20255212 0.07 ENST00000416372.1
RTN4R
reticulon 4 receptor
chrX_+_48687283 0.07 ENST00000338270.1
ERAS
ES cell expressed Ras

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX8

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.1 0.7 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.1 1.2 GO:0001661 conditioned taste aversion(GO:0001661)
0.1 1.7 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 0.5 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.1 0.3 GO:0030070 insulin processing(GO:0030070)
0.1 0.3 GO:0050712 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.1 0.2 GO:0099543 retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by trans-synaptic complex(GO:0099545)
0.1 0.2 GO:0034499 late endosome to Golgi transport(GO:0034499)
0.0 0.1 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.0 0.2 GO:0002905 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
0.0 0.8 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.2 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.0 0.1 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.0 0.1 GO:0060345 spleen trabecula formation(GO:0060345) iron cation export(GO:1903414) ferrous iron export(GO:1903988)
0.0 0.2 GO:0032764 negative regulation of mast cell cytokine production(GO:0032764) negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.0 0.3 GO:0046874 quinolinate metabolic process(GO:0046874)
0.0 0.2 GO:1903232 melanosome assembly(GO:1903232)
0.0 0.1 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.0 0.2 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.0 0.1 GO:0061193 sensory organ boundary specification(GO:0008052) formation of organ boundary(GO:0010160) taste bud development(GO:0061193)
0.0 0.1 GO:1904106 protein localization to microvillus(GO:1904106)
0.0 0.2 GO:2001184 positive regulation of interleukin-12 secretion(GO:2001184)
0.0 0.1 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.0 0.4 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.0 0.1 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.0 0.1 GO:0001172 transcription, RNA-templated(GO:0001172)
0.0 0.1 GO:0097403 cellular response to raffinose(GO:0097403) response to raffinose(GO:1901545)
0.0 0.2 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.0 0.2 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.0 0.3 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0 0.2 GO:0051026 chiasma assembly(GO:0051026)
0.0 0.2 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.5 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.1 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.0 0.1 GO:2000768 glomerular parietal epithelial cell differentiation(GO:0072139) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
0.0 0.1 GO:0070901 mitochondrial tRNA methylation(GO:0070901)
0.0 0.2 GO:2000332 blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.0 0.1 GO:1902045 negative regulation of Fas signaling pathway(GO:1902045)
0.0 0.1 GO:0043474 eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.0 0.1 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.4 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.2 GO:0042908 xenobiotic transport(GO:0042908)
0.0 0.3 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.0 0.0 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.0 0.0 GO:0006186 dADP phosphorylation(GO:0006174) dGDP phosphorylation(GO:0006186) AMP phosphorylation(GO:0006756) CDP phosphorylation(GO:0061508) dAMP phosphorylation(GO:0061565) CMP phosphorylation(GO:0061566) dCMP phosphorylation(GO:0061567) GDP phosphorylation(GO:0061568) UDP phosphorylation(GO:0061569) dCDP phosphorylation(GO:0061570) TDP phosphorylation(GO:0061571)
0.0 0.3 GO:0001574 ganglioside biosynthetic process(GO:0001574)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 GO:0035976 AP1 complex(GO:0035976)
0.1 1.6 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.2 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.3 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.2 GO:0032300 mismatch repair complex(GO:0032300)
0.0 0.2 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.1 GO:0036128 CatSper complex(GO:0036128)
0.0 0.7 GO:0031430 M band(GO:0031430)
0.0 0.0 GO:0036457 keratohyalin granule(GO:0036457)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0004947 bradykinin receptor activity(GO:0004947)
0.2 1.1 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.1 0.5 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.1 0.8 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 0.2 GO:0031177 phosphopantetheine binding(GO:0031177)
0.1 0.3 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.0 0.1 GO:0097689 iron channel activity(GO:0097689)
0.0 0.2 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.0 0.2 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0 0.1 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.0 0.1 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.0 0.4 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.1 GO:0072544 L-DOPA receptor activity(GO:0035643) L-DOPA binding(GO:0072544)
0.0 0.3 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.1 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.0 0.2 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.1 GO:0003968 RNA-directed RNA polymerase activity(GO:0003968)
0.0 0.1 GO:0005148 prolactin receptor binding(GO:0005148)
0.0 0.1 GO:0038131 neuregulin receptor activity(GO:0038131)
0.0 0.2 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.0 0.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.3 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.2 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 1.2 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.2 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.2 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.0 0.1 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.0 0.1 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.0 0.1 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.0 0.1 GO:0060422 peptidyl-dipeptidase inhibitor activity(GO:0060422)
0.0 0.1 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.0 0.1 GO:0009378 four-way junction helicase activity(GO:0009378)
0.0 0.1 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 0.1 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.1 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.2 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 1.7 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.9 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 1.4 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.8 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.3 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.1 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA