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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for SP100

Z-value: 1.62

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Transcription factors associated with SP100

Gene Symbol Gene ID Gene Info
SP100
ENSG00000067066.12 SP100 nuclear antigen

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SP100hg19_v2_chr2_+_231280908_2312809450.126.1e-01Click!

Activity profile of SP100 motif

Sorted Z-values of SP100 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_72143988 3.58 ENST00000506351.2
TNPO1
transportin 1
chr15_+_66797627 3.33 ENST00000565627.1
ENST00000564179.1
ZWILCH
zwilch kinetochore protein
chr5_+_179135246 2.96 ENST00000508787.1
CANX
calnexin
chr1_+_214776516 2.91 ENST00000366955.3
CENPF
centromere protein F, 350/400kDa
chr12_+_104682667 2.37 ENST00000527335.1
TXNRD1
thioredoxin reductase 1
chr7_-_91764108 2.18 ENST00000450723.1
CYP51A1
cytochrome P450, family 51, subfamily A, polypeptide 1
chr12_+_97306295 2.16 ENST00000457368.2
NEDD1
neural precursor cell expressed, developmentally down-regulated 1
chr5_+_137514687 2.15 ENST00000394894.3
KIF20A
kinesin family member 20A
chr15_+_66797455 1.97 ENST00000446801.2
ZWILCH
zwilch kinetochore protein
chr19_+_45147313 1.93 ENST00000406449.4
PVR
poliovirus receptor
chr16_+_66914264 1.83 ENST00000311765.2
ENST00000568869.1
ENST00000561704.1
ENST00000568398.1
ENST00000566776.1
PDP2
pyruvate dehyrogenase phosphatase catalytic subunit 2
chr7_-_35013217 1.82 ENST00000446375.1
DPY19L1
dpy-19-like 1 (C. elegans)
chr10_-_35379524 1.78 ENST00000374751.3
ENST00000374742.1
ENST00000602371.1
CUL2
cullin 2
chr18_-_74839891 1.74 ENST00000581878.1
MBP
myelin basic protein
chr22_-_28316116 1.71 ENST00000415296.1
PITPNB
phosphatidylinositol transfer protein, beta
chr12_-_122884553 1.71 ENST00000535290.1
CLIP1
CAP-GLY domain containing linker protein 1
chr6_-_18249971 1.67 ENST00000507591.1
DEK
DEK oncogene
chr7_-_81635106 1.67 ENST00000443883.1
CACNA2D1
calcium channel, voltage-dependent, alpha 2/delta subunit 1
chr12_+_97300995 1.66 ENST00000266742.4
ENST00000429527.2
ENST00000554226.1
ENST00000557478.1
ENST00000557092.1
ENST00000411739.2
ENST00000553609.1
NEDD1
neural precursor cell expressed, developmentally down-regulated 1
chr1_+_242011485 1.65 ENST00000423131.1
ENST00000523590.1
EXO1
exonuclease 1
chr3_+_156393349 1.64 ENST00000473702.1
TIPARP
TCDD-inducible poly(ADP-ribose) polymerase
chr14_-_39572345 1.60 ENST00000548032.2
ENST00000556092.1
ENST00000557280.1
ENST00000545328.2
ENST00000553970.1
SEC23A
Sec23 homolog A (S. cerevisiae)
chr9_+_104296163 1.58 ENST00000374819.2
ENST00000479306.1
RNF20
ring finger protein 20, E3 ubiquitin protein ligase
chr6_+_36410762 1.57 ENST00000483557.1
ENST00000498267.1
ENST00000544295.1
ENST00000449081.2
ENST00000536244.1
ENST00000460983.1
KCTD20
potassium channel tetramerization domain containing 20
chr6_+_163837347 1.56 ENST00000544436.1
QKI
QKI, KH domain containing, RNA binding
chr7_-_80551671 1.53 ENST00000419255.2
ENST00000544525.1
SEMA3C
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr5_+_137514403 1.53 ENST00000513276.1
KIF20A
kinesin family member 20A
chr7_-_124569991 1.52 ENST00000446993.1
ENST00000357628.3
ENST00000393329.1
POT1
protection of telomeres 1
chr5_+_110427983 1.48 ENST00000513710.2
ENST00000505303.1
WDR36
WD repeat domain 36
chr8_+_27629459 1.45 ENST00000523566.1
ESCO2
establishment of sister chromatid cohesion N-acetyltransferase 2
chr3_-_108308241 1.42 ENST00000295746.8
KIAA1524
KIAA1524
chr2_-_242211359 1.39 ENST00000444092.1
HDLBP
high density lipoprotein binding protein
chr1_-_108735440 1.39 ENST00000370041.4
SLC25A24
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
chr1_+_45205591 1.39 ENST00000455186.1
KIF2C
kinesin family member 2C
chr16_-_66907139 1.37 ENST00000561579.2
NAE1
NEDD8 activating enzyme E1 subunit 1
chr5_+_118604385 1.35 ENST00000274456.6
TNFAIP8
tumor necrosis factor, alpha-induced protein 8
chr14_+_31028348 1.34 ENST00000550944.1
ENST00000438909.2
ENST00000553504.1
G2E3
G2/M-phase specific E3 ubiquitin protein ligase
chr3_-_176914191 1.34 ENST00000437738.1
ENST00000424913.1
ENST00000443315.1
TBL1XR1
transducin (beta)-like 1 X-linked receptor 1
chr7_-_156685841 1.34 ENST00000354505.4
ENST00000540390.1
LMBR1
limb development membrane protein 1
chr1_+_90098606 1.33 ENST00000370454.4
LRRC8C
leucine rich repeat containing 8 family, member C
chr12_-_112546547 1.33 ENST00000547133.1
NAA25
N(alpha)-acetyltransferase 25, NatB auxiliary subunit
chr1_-_63988846 1.32 ENST00000283568.8
ENST00000371092.3
ENST00000271002.10
ITGB3BP
integrin beta 3 binding protein (beta3-endonexin)
chr2_-_111435610 1.31 ENST00000447014.1
ENST00000420328.1
ENST00000535254.1
ENST00000409311.1
ENST00000302759.6
BUB1
BUB1 mitotic checkpoint serine/threonine kinase
chr2_+_201390843 1.29 ENST00000357799.4
ENST00000409203.3
SGOL2
shugoshin-like 2 (S. pombe)
chr14_-_102605983 1.29 ENST00000334701.7
HSP90AA1
heat shock protein 90kDa alpha (cytosolic), class A member 1
chr6_+_42847649 1.29 ENST00000424341.2
ENST00000602561.1
RPL7L1
ribosomal protein L7-like 1
chr1_-_94344686 1.27 ENST00000528680.1
DNTTIP2
deoxynucleotidyltransferase, terminal, interacting protein 2
chr12_+_27863706 1.26 ENST00000081029.3
ENST00000538315.1
ENST00000542791.1
MRPS35
mitochondrial ribosomal protein S35
chr6_-_41888843 1.26 ENST00000434077.1
ENST00000409312.1
MED20
mediator complex subunit 20
chr5_+_169010638 1.26 ENST00000265295.4
ENST00000506574.1
ENST00000515224.1
ENST00000508247.1
ENST00000513941.1
SPDL1
spindle apparatus coiled-coil protein 1
chr14_+_57735725 1.25 ENST00000431972.2
AP5M1
adaptor-related protein complex 5, mu 1 subunit
chr2_+_28974489 1.25 ENST00000455580.1
PPP1CB
protein phosphatase 1, catalytic subunit, beta isozyme
chrX_+_100353153 1.24 ENST00000423383.1
ENST00000218507.5
ENST00000403304.2
ENST00000435570.1
CENPI
centromere protein I
chr4_+_41540160 1.23 ENST00000503057.1
ENST00000511496.1
LIMCH1
LIM and calponin homology domains 1
chr7_-_124569864 1.22 ENST00000609702.1
POT1
protection of telomeres 1
chr11_+_125496619 1.20 ENST00000532669.1
ENST00000278916.3
CHEK1
checkpoint kinase 1
chr8_-_42396185 1.19 ENST00000518717.1
SLC20A2
solute carrier family 20 (phosphate transporter), member 2
chrX_-_77395186 1.18 ENST00000341864.5
TAF9B
TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa
chr3_-_138553779 1.18 ENST00000461451.1
PIK3CB
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
chr5_-_159846066 1.16 ENST00000519349.1
ENST00000520664.1
SLU7
SLU7 splicing factor homolog (S. cerevisiae)
chr2_-_178417742 1.15 ENST00000408939.3
TTC30B
tetratricopeptide repeat domain 30B
chr10_-_27443294 1.14 ENST00000396296.3
ENST00000375972.3
ENST00000376016.3
ENST00000491542.2
YME1L1
YME1-like 1 ATPase
chr11_-_70963538 1.13 ENST00000413503.1
SHANK2
SH3 and multiple ankyrin repeat domains 2
chr17_+_46185111 1.12 ENST00000582104.1
ENST00000584335.1
SNX11
sorting nexin 11
chr11_+_125496400 1.12 ENST00000524737.1
CHEK1
checkpoint kinase 1
chr14_+_45605127 1.12 ENST00000556036.1
ENST00000267430.5
FANCM
Fanconi anemia, complementation group M
chr1_+_28099700 1.12 ENST00000440806.2
STX12
syntaxin 12
chr14_-_63974941 1.11 ENST00000422769.2
PPP2R5E
protein phosphatase 2, regulatory subunit B', epsilon isoform
chr18_-_46475696 1.10 ENST00000591805.1
SMAD7
SMAD family member 7
chr4_+_169418255 1.09 ENST00000505667.1
ENST00000511948.1
PALLD
palladin, cytoskeletal associated protein
chr10_-_91174215 1.09 ENST00000371837.1
LIPA
lipase A, lysosomal acid, cholesterol esterase
chr3_+_111393501 1.08 ENST00000393934.3
PLCXD2
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr16_+_71392616 1.07 ENST00000349553.5
ENST00000302628.4
ENST00000562305.1
CALB2
calbindin 2
chr2_+_28974531 1.05 ENST00000420282.1
PPP1CB
protein phosphatase 1, catalytic subunit, beta isozyme
chr5_+_137514834 1.05 ENST00000508792.1
ENST00000504621.1
KIF20A
kinesin family member 20A
chr13_-_31736027 1.04 ENST00000380406.5
ENST00000320027.5
ENST00000380405.4
HSPH1
heat shock 105kDa/110kDa protein 1
chr19_+_37960240 1.03 ENST00000388801.3
ZNF570
zinc finger protein 570
chr5_+_33440802 1.03 ENST00000502553.1
ENST00000514259.1
ENST00000265112.3
TARS
threonyl-tRNA synthetase
chr8_+_27631903 1.02 ENST00000305188.8
ESCO2
establishment of sister chromatid cohesion N-acetyltransferase 2
chr10_+_43916052 1.02 ENST00000442526.2
RP11-517P14.2
RP11-517P14.2
chr6_+_57182400 1.00 ENST00000607273.1
PRIM2
primase, DNA, polypeptide 2 (58kDa)
chr13_-_30169807 0.97 ENST00000380752.5
SLC7A1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr17_+_61271355 0.97 ENST00000583356.1
TANC2
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr8_+_48873453 0.97 ENST00000523944.1
MCM4
minichromosome maintenance complex component 4
chr9_+_112887772 0.96 ENST00000259318.7
AKAP2
A kinase (PRKA) anchor protein 2
chr14_-_91976874 0.96 ENST00000557018.1
SMEK1
SMEK homolog 1, suppressor of mek1 (Dictyostelium)
chr19_-_55767125 0.95 ENST00000592242.1
PPP6R1
protein phosphatase 6, regulatory subunit 1
chr2_-_113191096 0.95 ENST00000496537.1
ENST00000330575.5
ENST00000302558.3
RGPD8
RANBP2-like and GRIP domain containing 8
chr3_+_62304648 0.95 ENST00000462069.1
ENST00000232519.5
ENST00000465142.1
C3orf14
chromosome 3 open reading frame 14
chr2_+_192109911 0.95 ENST00000418908.1
ENST00000339514.4
ENST00000392318.3
MYO1B
myosin IB
chr5_-_40755987 0.95 ENST00000337702.4
TTC33
tetratricopeptide repeat domain 33
chr14_-_102552659 0.94 ENST00000441629.2
HSP90AA1
heat shock protein 90kDa alpha (cytosolic), class A member 1
chr8_+_75262629 0.94 ENST00000434412.2
GDAP1
ganglioside induced differentiation associated protein 1
chr9_-_99775862 0.94 ENST00000602917.1
ENST00000375223.4
HIATL2
hippocampus abundant transcript-like 2
chr3_-_11685345 0.94 ENST00000430365.2
VGLL4
vestigial like 4 (Drosophila)
chr19_+_53836985 0.94 ENST00000601857.1
ENST00000595091.1
ENST00000458035.1
ZNF845
zinc finger protein 845
chr10_-_30637906 0.93 ENST00000417581.1
MTPAP
mitochondrial poly(A) polymerase
chr8_+_72755367 0.93 ENST00000537896.1
RP11-383H13.1
Protein LOC100132891; cDNA FLJ53548
chr5_+_151151504 0.93 ENST00000356245.3
ENST00000507878.2
G3BP1
GTPase activating protein (SH3 domain) binding protein 1
chr21_-_34915084 0.93 ENST00000426819.1
GART
phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
chr17_-_40021656 0.92 ENST00000319121.3
KLHL11
kelch-like family member 11
chr1_+_227751231 0.92 ENST00000343776.5
ENST00000608949.1
ENST00000397097.3
ZNF678
zinc finger protein 678
chr4_+_128802016 0.92 ENST00000270861.5
ENST00000515069.1
ENST00000513090.1
ENST00000507249.1
PLK4
polo-like kinase 4
chr12_-_110318130 0.91 ENST00000540772.1
GLTP
glycolipid transfer protein
chr7_+_98971863 0.91 ENST00000443222.1
ENST00000414376.1
ARPC1B
actin related protein 2/3 complex, subunit 1B, 41kDa
chr6_+_96969672 0.90 ENST00000369278.4
UFL1
UFM1-specific ligase 1
chr18_+_21033239 0.90 ENST00000581585.1
ENST00000577501.1
RIOK3
RIO kinase 3
chr5_+_121297650 0.89 ENST00000339397.4
SRFBP1
serum response factor binding protein 1
chr8_-_142012169 0.88 ENST00000517453.1
PTK2
protein tyrosine kinase 2
chr16_+_85936295 0.88 ENST00000563180.1
ENST00000564617.1
ENST00000564803.1
IRF8
interferon regulatory factor 8
chr12_+_69004805 0.88 ENST00000541216.1
RAP1B
RAP1B, member of RAS oncogene family
chr15_-_67546963 0.87 ENST00000561452.1
ENST00000261880.5
AAGAB
alpha- and gamma-adaptin binding protein
chrX_-_20159934 0.87 ENST00000379593.1
ENST00000379607.5
EIF1AX
eukaryotic translation initiation factor 1A, X-linked
chr1_+_45205498 0.87 ENST00000372218.4
KIF2C
kinesin family member 2C
chr12_-_120884175 0.87 ENST00000546954.1
TRIAP1
TP53 regulated inhibitor of apoptosis 1
chr13_-_31736478 0.86 ENST00000445273.2
HSPH1
heat shock 105kDa/110kDa protein 1
chr20_+_5931497 0.86 ENST00000378886.2
ENST00000265187.4
MCM8
minichromosome maintenance complex component 8
chr16_+_2213530 0.85 ENST00000567645.1
TRAF7
TNF receptor-associated factor 7, E3 ubiquitin protein ligase
chr11_+_125495862 0.85 ENST00000428830.2
ENST00000544373.1
ENST00000527013.1
ENST00000526937.1
ENST00000534685.1
CHEK1
checkpoint kinase 1
chr1_-_236767779 0.85 ENST00000366579.1
ENST00000366582.3
ENST00000366581.2
HEATR1
HEAT repeat containing 1
chr2_+_189156586 0.85 ENST00000409830.1
GULP1
GULP, engulfment adaptor PTB domain containing 1
chr4_+_113152881 0.84 ENST00000274000.5
AP1AR
adaptor-related protein complex 1 associated regulatory protein
chrX_+_70586140 0.84 ENST00000276072.3
TAF1
TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
chr21_-_30365136 0.84 ENST00000361371.5
ENST00000389194.2
ENST00000389195.2
LTN1
listerin E3 ubiquitin protein ligase 1
chr9_-_88896977 0.83 ENST00000311534.6
ISCA1
iron-sulfur cluster assembly 1
chr14_+_31028329 0.83 ENST00000206595.6
G2E3
G2/M-phase specific E3 ubiquitin protein ligase
chr13_-_31736132 0.83 ENST00000429785.2
HSPH1
heat shock 105kDa/110kDa protein 1
chr2_+_157291953 0.82 ENST00000310454.6
GPD2
glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
chr2_+_29353520 0.82 ENST00000438819.1
CLIP4
CAP-GLY domain containing linker protein family, member 4
chr4_-_89079817 0.82 ENST00000505480.1
ABCG2
ATP-binding cassette, sub-family G (WHITE), member 2
chr4_-_76861392 0.81 ENST00000505594.1
NAAA
N-acylethanolamine acid amidase
chr7_-_108168580 0.81 ENST00000453085.1
PNPLA8
patatin-like phospholipase domain containing 8
chr6_-_28554977 0.80 ENST00000452236.2
SCAND3
SCAN domain containing 3
chr12_+_120884222 0.80 ENST00000551765.1
ENST00000229384.5
GATC
glutamyl-tRNA(Gln) amidotransferase, subunit C
chr9_-_95087604 0.80 ENST00000542613.1
ENST00000542053.1
ENST00000358855.4
ENST00000545558.1
ENST00000432670.2
ENST00000433029.2
ENST00000411621.2
NOL8
nucleolar protein 8
chr9_-_139372141 0.80 ENST00000313050.7
SEC16A
SEC16 homolog A (S. cerevisiae)
chr2_+_122513109 0.79 ENST00000389682.3
ENST00000536142.1
TSN
translin
chr15_+_59397298 0.79 ENST00000559622.1
CCNB2
cyclin B2
chr9_-_135230336 0.79 ENST00000224140.5
ENST00000372169.2
ENST00000393220.1
SETX
senataxin
chr5_-_55008101 0.78 ENST00000506624.1
ENST00000513275.1
ENST00000513993.1
SLC38A9
solute carrier family 38, member 9
chr14_+_50065376 0.78 ENST00000298288.6
LRR1
leucine rich repeat protein 1
chr17_+_65713925 0.78 ENST00000253247.4
NOL11
nucleolar protein 11
chr1_-_23694794 0.78 ENST00000374608.3
ZNF436
zinc finger protein 436
chr15_-_90358564 0.77 ENST00000559874.1
ANPEP
alanyl (membrane) aminopeptidase
chr3_-_125094093 0.77 ENST00000484491.1
ENST00000492394.1
ENST00000471196.1
ENST00000468369.1
ENST00000544464.1
ENST00000485866.1
ENST00000360647.4
ZNF148
zinc finger protein 148
chr21_+_30672433 0.77 ENST00000451655.1
BACH1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr15_+_55611401 0.76 ENST00000566999.1
PIGB
phosphatidylinositol glycan anchor biosynthesis, class B
chr4_-_54232144 0.76 ENST00000388940.4
ENST00000503450.1
ENST00000401642.3
SCFD2
sec1 family domain containing 2
chr8_-_104427289 0.76 ENST00000543107.1
SLC25A32
solute carrier family 25 (mitochondrial folate carrier), member 32
chr12_+_13044787 0.75 ENST00000534831.1
GPRC5A
G protein-coupled receptor, family C, group 5, member A
chrX_+_108780347 0.75 ENST00000372103.1
NXT2
nuclear transport factor 2-like export factor 2
chr2_+_158114051 0.75 ENST00000259056.4
GALNT5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)
chr2_+_192110199 0.75 ENST00000304164.4
MYO1B
myosin IB
chr10_+_35416223 0.74 ENST00000489321.1
ENST00000427847.2
ENST00000345491.3
ENST00000395895.2
ENST00000374728.3
ENST00000487132.1
CREM
cAMP responsive element modulator
chr7_+_131012605 0.74 ENST00000446815.1
ENST00000352689.6
MKLN1
muskelin 1, intracellular mediator containing kelch motifs
chr5_+_54455946 0.74 ENST00000503787.1
ENST00000296734.6
ENST00000515370.1
GPX8
glutathione peroxidase 8 (putative)
chr5_-_55008136 0.73 ENST00000503891.1
ENST00000507109.1
SLC38A9
solute carrier family 38, member 9
chr6_-_116601044 0.73 ENST00000368608.3
TSPYL1
TSPY-like 1
chr14_+_24899141 0.72 ENST00000556842.1
ENST00000553935.1
KHNYN
KH and NYN domain containing
chr2_-_224810070 0.72 ENST00000429915.1
ENST00000233055.4
WDFY1
WD repeat and FYVE domain containing 1
chr15_+_59397275 0.72 ENST00000288207.2
CCNB2
cyclin B2
chr6_+_27861190 0.72 ENST00000303806.4
HIST1H2BO
histone cluster 1, H2bo
chr15_+_68570062 0.71 ENST00000306917.4
FEM1B
fem-1 homolog b (C. elegans)
chr11_-_33744487 0.71 ENST00000426650.2
CD59
CD59 molecule, complement regulatory protein
chr5_+_33441053 0.71 ENST00000541634.1
ENST00000455217.2
ENST00000414361.2
TARS
threonyl-tRNA synthetase
chrX_+_21959108 0.71 ENST00000457085.1
SMS
spermine synthase
chr1_+_63989004 0.71 ENST00000371088.4
EFCAB7
EF-hand calcium binding domain 7
chr18_-_46895066 0.70 ENST00000583225.1
ENST00000584983.1
ENST00000583280.1
ENST00000581738.1
DYM
dymeclin
chr1_+_231473990 0.70 ENST00000008440.9
SPRTN
SprT-like N-terminal domain
chr3_-_37218023 0.70 ENST00000416425.1
LRRFIP2
leucine rich repeat (in FLII) interacting protein 2
chr1_+_231473743 0.70 ENST00000295050.7
SPRTN
SprT-like N-terminal domain
chr8_-_95487331 0.69 ENST00000336148.5
RAD54B
RAD54 homolog B (S. cerevisiae)
chr14_+_45605157 0.69 ENST00000542564.2
FANCM
Fanconi anemia, complementation group M
chr2_-_172291273 0.69 ENST00000442778.1
ENST00000453846.1
METTL8
methyltransferase like 8
chr10_-_123687943 0.69 ENST00000540606.1
ENST00000455628.1
ATE1
arginyltransferase 1
chr9_+_104296122 0.68 ENST00000389120.3
RNF20
ring finger protein 20, E3 ubiquitin protein ligase
chr19_+_35773242 0.68 ENST00000222304.3
HAMP
hepcidin antimicrobial peptide
chr2_-_216003127 0.68 ENST00000412081.1
ENST00000272895.7
ABCA12
ATP-binding cassette, sub-family A (ABC1), member 12
chr3_-_16306432 0.68 ENST00000383775.4
ENST00000488423.1
DPH3
diphthamide biosynthesis 3
chr18_-_43547223 0.68 ENST00000282041.5
EPG5
ectopic P-granules autophagy protein 5 homolog (C. elegans)
chr17_-_2415169 0.68 ENST00000263092.6
ENST00000538844.1
ENST00000576976.1
METTL16
methyltransferase like 16
chr2_-_178129551 0.68 ENST00000430047.1
NFE2L2
nuclear factor, erythroid 2-like 2
chr8_+_17780483 0.67 ENST00000517730.1
ENST00000518537.1
ENST00000523055.1
ENST00000519253.1
PCM1
pericentriolar material 1
chr7_+_148844516 0.67 ENST00000420008.2
ENST00000475153.1
ZNF398
zinc finger protein 398
chr6_-_109804412 0.67 ENST00000230122.3
ZBTB24
zinc finger and BTB domain containing 24
chr9_+_33265011 0.67 ENST00000419016.2
CHMP5
charged multivesicular body protein 5
chr13_+_103498143 0.66 ENST00000535557.1
ERCC5
excision repair cross-complementing rodent repair deficiency, complementation group 5
chr6_-_30684898 0.66 ENST00000422266.1
ENST00000416571.1
MDC1
mediator of DNA-damage checkpoint 1
chr17_-_36003487 0.66 ENST00000394367.3
ENST00000349699.2
DDX52
DEAD (Asp-Glu-Ala-Asp) box polypeptide 52
chr5_+_148651469 0.66 ENST00000515000.1
AFAP1L1
actin filament associated protein 1-like 1
chr10_+_112327425 0.66 ENST00000361804.4
SMC3
structural maintenance of chromosomes 3
chr5_-_76788024 0.66 ENST00000515253.1
ENST00000414719.2
ENST00000507654.1
ENST00000514559.1
ENST00000511791.1
WDR41
WD repeat domain 41
chr9_+_97136833 0.66 ENST00000375344.3
HIATL1
hippocampus abundant transcript-like 1
chr15_+_45879321 0.65 ENST00000220531.3
ENST00000567461.1
BLOC1S6
biogenesis of lysosomal organelles complex-1, subunit 6, pallidin
chr15_-_72410306 0.65 ENST00000566885.1
MYO9A
myosin IXA
chr2_+_201994042 0.65 ENST00000417748.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr8_+_75262612 0.65 ENST00000220822.7
GDAP1
ganglioside induced differentiation associated protein 1
chr21_-_34915123 0.65 ENST00000438059.1
GART
phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
chr12_-_30907749 0.64 ENST00000542550.1
ENST00000540584.1
CAPRIN2
caprin family member 2
chr6_-_127664475 0.64 ENST00000474289.2
ENST00000534442.1
ENST00000368289.2
ENST00000525745.1
ENST00000430841.2
ECHDC1
enoyl CoA hydratase domain containing 1

Network of associatons between targets according to the STRING database.

First level regulatory network of SP100

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.7 GO:0060382 regulation of DNA strand elongation(GO:0060382)
0.7 2.2 GO:0033488 cholesterol biosynthetic process via 24,25-dihydrolanosterol(GO:0033488)
0.6 1.9 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.6 3.8 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.4 2.2 GO:0043335 protein unfolding(GO:0043335)
0.4 1.7 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
0.4 2.5 GO:0034421 post-translational protein acetylation(GO:0034421)
0.3 2.7 GO:1903750 regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
0.3 1.3 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.3 1.2 GO:0001971 negative regulation of activation of membrane attack complex(GO:0001971)
0.3 1.7 GO:1904207 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.3 2.8 GO:2001166 regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.3 0.8 GO:0048203 vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.3 1.1 GO:0002725 negative regulation of T cell cytokine production(GO:0002725)
0.3 0.8 GO:0006433 prolyl-tRNA aminoacylation(GO:0006433)
0.3 0.8 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.2 1.7 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.2 0.7 GO:1904479 cellular response to bile acid(GO:1903413) negative regulation of intestinal absorption(GO:1904479) response to iron ion starvation(GO:1990641)
0.2 1.1 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.2 5.9 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.2 0.6 GO:0034059 response to anoxia(GO:0034059) positive regulation of penile erection(GO:0060406)
0.2 0.8 GO:0010767 regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage(GO:0010767)
0.2 1.7 GO:0086048 membrane depolarization during bundle of His cell action potential(GO:0086048)
0.2 0.8 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.2 2.8 GO:0001887 selenium compound metabolic process(GO:0001887)
0.2 1.2 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.2 0.6 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.2 0.6 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.2 0.8 GO:0035350 FAD transport(GO:0015883) FAD transmembrane transport(GO:0035350)
0.2 2.3 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.2 0.9 GO:0046601 positive regulation of centriole replication(GO:0046601)
0.2 1.2 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.2 0.7 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.2 2.0 GO:0018406 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.2 1.2 GO:1990592 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.2 0.7 GO:0006597 spermine biosynthetic process(GO:0006597)
0.2 3.1 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.2 1.2 GO:0046836 glycolipid transport(GO:0046836)
0.2 0.7 GO:0016598 protein arginylation(GO:0016598)
0.2 0.7 GO:0035627 ceramide transport(GO:0035627)
0.2 0.5 GO:1903452 regulation of G1 to G0 transition(GO:1903450) positive regulation of G1 to G0 transition(GO:1903452)
0.2 1.0 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.2 0.8 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.2 1.0 GO:0001927 exocyst assembly(GO:0001927)
0.2 1.9 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.2 0.6 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.2 0.2 GO:0090210 regulation of establishment of blood-brain barrier(GO:0090210) negative regulation of establishment of blood-brain barrier(GO:0090212)
0.2 0.8 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.1 0.7 GO:0070124 mitochondrial translational initiation(GO:0070124)
0.1 1.3 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1 1.1 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.1 0.6 GO:0006408 snRNA export from nucleus(GO:0006408)
0.1 0.8 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.1 0.4 GO:1902771 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.1 0.4 GO:0009405 pathogenesis(GO:0009405)
0.1 1.5 GO:0003350 pulmonary myocardium development(GO:0003350)
0.1 4.5 GO:0071539 protein localization to centrosome(GO:0071539)
0.1 2.9 GO:0051382 kinetochore assembly(GO:0051382)
0.1 2.3 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.1 1.0 GO:1903826 arginine transmembrane transport(GO:1903826)
0.1 1.5 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 0.5 GO:1903660 negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.1 0.6 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.1 0.5 GO:0033499 galactose catabolic process via UDP-galactose(GO:0033499)
0.1 0.5 GO:1990927 negative regulation of membrane invagination(GO:1905154) calcium ion regulated lysosome exocytosis(GO:1990927)
0.1 0.4 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
0.1 0.5 GO:0071874 cellular response to norepinephrine stimulus(GO:0071874)
0.1 0.6 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.1 1.7 GO:0015867 ATP transport(GO:0015867)
0.1 0.4 GO:0031456 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.1 1.4 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.1 0.6 GO:0060809 mesodermal to mesenchymal transition involved in gastrulation(GO:0060809)
0.1 3.2 GO:1902166 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902166)
0.1 0.7 GO:1903788 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.1 1.8 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.1 1.6 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.1 0.6 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.1 0.6 GO:0001712 ectodermal cell fate commitment(GO:0001712)
0.1 0.3 GO:0071109 superior temporal gyrus development(GO:0071109)
0.1 1.8 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.1 1.3 GO:0034501 protein localization to kinetochore(GO:0034501)
0.1 1.3 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.1 0.5 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.1 1.7 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.1 1.0 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.1 1.0 GO:1903943 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.1 0.7 GO:0070475 rRNA base methylation(GO:0070475) mRNA methylation(GO:0080009)
0.1 0.9 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.1 0.3 GO:0000103 sulfate assimilation(GO:0000103)
0.1 0.7 GO:0044789 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.1 0.3 GO:0051066 dihydrobiopterin metabolic process(GO:0051066)
0.1 0.6 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.1 0.4 GO:0009213 pyrimidine nucleoside triphosphate catabolic process(GO:0009149) pyrimidine deoxyribonucleoside triphosphate catabolic process(GO:0009213)
0.1 0.3 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.1 0.3 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.1 2.7 GO:0061641 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.1 1.1 GO:0071816 tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.1 0.2 GO:1903568 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.1 1.6 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 0.8 GO:1902570 protein localization to nucleolus(GO:1902570)
0.1 0.6 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.1 0.5 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.1 1.5 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.1 1.3 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.1 0.3 GO:0046110 xanthine metabolic process(GO:0046110)
0.1 1.5 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.1 0.5 GO:0019348 dolichol metabolic process(GO:0019348)
0.1 1.4 GO:0034384 high-density lipoprotein particle clearance(GO:0034384)
0.1 0.5 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.1 1.2 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.1 0.6 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.1 0.6 GO:0072733 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.1 0.5 GO:0030242 pexophagy(GO:0030242)
0.1 0.2 GO:0032242 regulation of nucleoside transport(GO:0032242) positive regulation of necroptotic process(GO:0060545)
0.1 0.9 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.1 0.3 GO:2000672 cellular response to sorbitol(GO:0072709) negative regulation of motor neuron apoptotic process(GO:2000672)
0.1 1.6 GO:0003334 keratinocyte development(GO:0003334)
0.1 0.5 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.1 1.6 GO:0097502 mannosylation(GO:0097502)
0.1 0.3 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.1 0.8 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.1 0.3 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.1 0.2 GO:0021997 response to chlorate(GO:0010157) neural plate axis specification(GO:0021997)
0.1 0.3 GO:0006203 dGTP catabolic process(GO:0006203)
0.1 1.7 GO:0002021 response to dietary excess(GO:0002021)
0.1 0.8 GO:0042908 xenobiotic transport(GO:0042908)
0.1 0.3 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.1 0.4 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 0.4 GO:0033146 regulation of intracellular estrogen receptor signaling pathway(GO:0033146)
0.1 1.8 GO:0008053 mitochondrial fusion(GO:0008053)
0.1 0.6 GO:0070197 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.1 0.5 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.1 0.2 GO:1902165 regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902165)
0.0 0.3 GO:0044034 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.0 0.8 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.0 1.6 GO:0042327 positive regulation of phosphorylation(GO:0042327)
0.0 0.8 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.2 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.0 0.2 GO:0006601 creatine biosynthetic process(GO:0006601)
0.0 0.8 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.6 GO:0034141 positive regulation of toll-like receptor 3 signaling pathway(GO:0034141)
0.0 0.3 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.0 0.3 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.5 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.0 0.4 GO:0015074 DNA integration(GO:0015074)
0.0 0.8 GO:2000304 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0 0.5 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.1 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.0 0.4 GO:0048318 axial mesoderm development(GO:0048318)
0.0 0.6 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.3 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.2 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.0 6.0 GO:0007062 sister chromatid cohesion(GO:0007062)
0.0 1.9 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.7 GO:0010225 response to UV-C(GO:0010225)
0.0 0.2 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.0 0.6 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 1.6 GO:0060325 face morphogenesis(GO:0060325)
0.0 2.5 GO:0007077 mitotic nuclear envelope disassembly(GO:0007077)
0.0 1.8 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.3 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
0.0 0.3 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.9 GO:0042178 xenobiotic catabolic process(GO:0042178)
0.0 0.8 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.5 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.2 GO:0046092 deoxycytidine metabolic process(GO:0046092)
0.0 0.8 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.5 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.4 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.6 GO:0010818 T cell chemotaxis(GO:0010818)
0.0 1.5 GO:0033344 cholesterol efflux(GO:0033344)
0.0 1.1 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0 0.7 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 1.1 GO:0071625 vocalization behavior(GO:0071625)
0.0 0.9 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.3 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 1.0 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 0.3 GO:0097084 vascular smooth muscle cell development(GO:0097084)
0.0 1.2 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 0.5 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.0 0.4 GO:0006578 amino-acid betaine biosynthetic process(GO:0006578) carnitine biosynthetic process(GO:0045329)
0.0 0.1 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.0 0.3 GO:0006983 ER overload response(GO:0006983)
0.0 1.2 GO:2000179 positive regulation of neural precursor cell proliferation(GO:2000179)
0.0 0.7 GO:0006853 carnitine shuttle(GO:0006853)
0.0 0.4 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.6 GO:0044130 negative regulation of growth of symbiont in host(GO:0044130)
0.0 1.8 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.7 GO:0006312 mitotic recombination(GO:0006312)
0.0 0.3 GO:0032808 lacrimal gland development(GO:0032808)
0.0 1.1 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.0 0.9 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.1 GO:2000627 rRNA import into mitochondrion(GO:0035928) regulation of miRNA catabolic process(GO:2000625) positive regulation of miRNA catabolic process(GO:2000627)
0.0 0.4 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.0 0.9 GO:0043243 positive regulation of protein complex disassembly(GO:0043243)
0.0 0.4 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.3 GO:0021819 layer formation in cerebral cortex(GO:0021819)
0.0 0.2 GO:0007249 I-kappaB kinase/NF-kappaB signaling(GO:0007249)
0.0 0.2 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 0.3 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0 1.0 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 0.4 GO:0016081 synaptic vesicle docking(GO:0016081) positive regulation of pigment cell differentiation(GO:0050942)
0.0 0.1 GO:0019085 early viral transcription(GO:0019085)
0.0 0.1 GO:0016139 glycoside catabolic process(GO:0016139)
0.0 1.2 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.1 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.4 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.4 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.2 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.0 0.2 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.0 0.2 GO:0010826 negative regulation of centrosome duplication(GO:0010826)
0.0 0.4 GO:0051560 mitochondrial calcium ion homeostasis(GO:0051560)
0.0 0.3 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.1 GO:0051892 negative regulation of cardioblast differentiation(GO:0051892) regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.0 0.2 GO:0060148 positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637)
0.0 1.2 GO:0021762 substantia nigra development(GO:0021762)
0.0 0.1 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 1.0 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 0.5 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.9 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.8 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.5 GO:0009303 rRNA transcription(GO:0009303)
0.0 0.4 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.6 GO:0015012 heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.0 0.8 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.2 GO:0070672 response to interleukin-15(GO:0070672)
0.0 0.9 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.7 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 0.3 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.1 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065) UDP-glucuronate metabolic process(GO:0046398)
0.0 0.7 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.1 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.1 GO:0071918 urea transmembrane transport(GO:0071918)
0.0 0.3 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.3 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 1.0 GO:0006911 phagocytosis, engulfment(GO:0006911)
0.0 1.1 GO:0001895 retina homeostasis(GO:0001895)
0.0 0.9 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.1 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0 0.1 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.1 GO:0016572 histone phosphorylation(GO:0016572)
0.0 0.2 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 1.1 GO:0000070 mitotic sister chromatid segregation(GO:0000070)
0.0 0.3 GO:1902894 negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.0 0.3 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.0 0.5 GO:0008333 endosome to lysosome transport(GO:0008333)
0.0 0.5 GO:0048488 synaptic vesicle endocytosis(GO:0048488)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 5.3 GO:1990423 RZZ complex(GO:1990423)
0.6 1.8 GO:0071821 FANCM-MHF complex(GO:0071821)
0.5 1.6 GO:0034455 t-UTP complex(GO:0034455)
0.3 1.8 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.3 5.5 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.3 2.9 GO:0033503 HULC complex(GO:0033503)
0.3 1.4 GO:0097362 MCM8-MCM9 complex(GO:0097362)
0.3 0.8 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.2 0.9 GO:0036284 tubulobulbar complex(GO:0036284)
0.2 1.8 GO:0030891 VCB complex(GO:0030891)
0.2 1.5 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.2 3.4 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.2 3.4 GO:0001741 XY body(GO:0001741)
0.2 1.6 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.2 2.7 GO:0070187 telosome(GO:0070187)
0.2 2.3 GO:0042587 glycogen granule(GO:0042587)
0.2 1.7 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.2 5.3 GO:0000242 pericentriolar material(GO:0000242)
0.1 0.4 GO:0032783 ELL-EAF complex(GO:0032783)
0.1 1.8 GO:0071986 Ragulator complex(GO:0071986)
0.1 4.2 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.1 1.7 GO:0033269 internode region of axon(GO:0033269)
0.1 2.3 GO:0000124 SAGA complex(GO:0000124)
0.1 0.5 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.1 0.8 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1 0.5 GO:0031523 Myb complex(GO:0031523)
0.1 0.5 GO:0031592 centrosomal corona(GO:0031592)
0.1 0.6 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.1 0.7 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.1 1.5 GO:0042555 MCM complex(GO:0042555)
0.1 1.7 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 0.7 GO:0097209 epidermal lamellar body(GO:0097209)
0.1 0.5 GO:0000799 nuclear condensin complex(GO:0000799)
0.1 1.0 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 0.5 GO:0030870 Mre11 complex(GO:0030870)
0.1 0.5 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.1 1.1 GO:0005883 neurofilament(GO:0005883)
0.1 0.6 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 0.3 GO:0045257 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.1 7.1 GO:0005871 kinesin complex(GO:0005871)
0.1 0.5 GO:0035253 ciliary rootlet(GO:0035253)
0.1 2.0 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 0.4 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.1 1.2 GO:0016461 unconventional myosin complex(GO:0016461)
0.1 1.9 GO:0031083 BLOC-1 complex(GO:0031083)
0.1 0.5 GO:0097452 GAIT complex(GO:0097452)
0.1 0.3 GO:1990246 uniplex complex(GO:1990246)
0.1 1.1 GO:0016342 catenin complex(GO:0016342)
0.0 1.2 GO:0097342 ripoptosome(GO:0097342)
0.0 0.3 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.7 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.6 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.5 GO:0097255 R2TP complex(GO:0097255)
0.0 1.4 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.8 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.2 GO:0031213 RSF complex(GO:0031213)
0.0 0.7 GO:0045179 apical cortex(GO:0045179)
0.0 0.6 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.7 GO:0005675 holo TFIIH complex(GO:0005675)
0.0 2.1 GO:0016592 mediator complex(GO:0016592)
0.0 0.3 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.0 0.7 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 1.0 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.1 GO:0032002 interleukin-28 receptor complex(GO:0032002)
0.0 0.4 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.4 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 1.2 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 2.6 GO:0002102 podosome(GO:0002102)
0.0 0.7 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.0 0.2 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.2 GO:0036038 MKS complex(GO:0036038)
0.0 0.3 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.9 GO:0030686 90S preribosome(GO:0030686)
0.0 0.6 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 1.2 GO:0005921 gap junction(GO:0005921)
0.0 0.3 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 2.0 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.4 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 3.2 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.0 0.3 GO:1990909 Wnt signalosome(GO:1990909)
0.0 0.2 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.0 0.7 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.4 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.3 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.6 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 2.5 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.2 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.2 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.8 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.5 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.6 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 1.1 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.8 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 1.0 GO:0000145 exocyst(GO:0000145)
0.0 2.8 GO:0000776 kinetochore(GO:0000776)
0.0 2.8 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 1.8 GO:0005643 nuclear pore(GO:0005643)
0.0 0.2 GO:0000346 transcription export complex(GO:0000346)
0.0 0.2 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.5 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.1 GO:0002079 inner acrosomal membrane(GO:0002079)
0.0 0.3 GO:0031045 dense core granule(GO:0031045)
0.0 1.5 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.4 GO:0035267 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 1.5 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.3 GO:0030057 desmosome(GO:0030057)
0.0 0.6 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.9 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:0008398 sterol 14-demethylase activity(GO:0008398)
0.6 3.8 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.6 1.7 GO:0086057 voltage-gated calcium channel activity involved in bundle of His cell action potential(GO:0086057)
0.6 2.8 GO:0098625 methylselenol reductase activity(GO:0098625) methylseleninic acid reductase activity(GO:0098626)
0.5 1.6 GO:0051908 double-stranded DNA 5'-3' exodeoxyribonuclease activity(GO:0051908)
0.5 1.9 GO:0004644 phosphoribosylamine-glycine ligase activity(GO:0004637) phosphoribosylformylglycinamidine cyclo-ligase activity(GO:0004641) phosphoribosylglycinamide formyltransferase activity(GO:0004644)
0.5 2.3 GO:0050115 myosin-light-chain-phosphatase activity(GO:0050115)
0.5 2.7 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.5 1.4 GO:0019781 NEDD8 activating enzyme activity(GO:0019781)
0.4 1.7 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.4 1.5 GO:0032551 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
0.4 1.1 GO:0030617 transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity(GO:0030617)
0.3 2.5 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.3 0.8 GO:0004827 proline-tRNA ligase activity(GO:0004827)
0.3 0.8 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.3 0.8 GO:0001147 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.3 1.8 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.3 1.0 GO:0003896 DNA primase activity(GO:0003896)
0.2 0.7 GO:0016768 spermine synthase activity(GO:0016768)
0.2 0.7 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.2 3.1 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.2 0.8 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.2 0.8 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.2 0.8 GO:0052591 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.2 2.3 GO:0019237 centromeric DNA binding(GO:0019237)
0.2 2.2 GO:0030911 TPR domain binding(GO:0030911)
0.2 0.8 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.2 0.8 GO:0015230 FAD transmembrane transporter activity(GO:0015230)
0.2 0.9 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.2 0.9 GO:0017089 glycolipid transporter activity(GO:0017089)
0.2 1.2 GO:0070404 NADH binding(GO:0070404)
0.2 0.9 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.2 0.7 GO:0015616 DNA translocase activity(GO:0015616)
0.2 0.7 GO:0004057 arginyltransferase activity(GO:0004057)
0.2 1.7 GO:0043515 kinetochore binding(GO:0043515)
0.2 0.7 GO:0034040 lipid-transporting ATPase activity(GO:0034040)
0.2 1.2 GO:0004376 glycolipid mannosyltransferase activity(GO:0004376)
0.2 0.7 GO:0036033 mediator complex binding(GO:0036033)
0.2 0.6 GO:0004492 methylmalonyl-CoA decarboxylase activity(GO:0004492)
0.1 1.1 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.1 0.4 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.1 2.3 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.1 1.1 GO:0004771 sterol esterase activity(GO:0004771)
0.1 1.1 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.1 0.5 GO:0051734 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.1 0.5 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.1 1.2 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.1 0.3 GO:0004779 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.1 1.0 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.1 1.2 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 0.6 GO:0070644 vitamin D response element binding(GO:0070644)
0.1 0.5 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.1 1.7 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 0.5 GO:0004905 type I interferon receptor activity(GO:0004905)
0.1 1.4 GO:0005347 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.1 3.0 GO:0034185 apolipoprotein binding(GO:0034185)
0.1 2.1 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 0.7 GO:0000405 bubble DNA binding(GO:0000405)
0.1 0.3 GO:0030626 U12 snRNA binding(GO:0030626)
0.1 0.3 GO:0008413 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539)
0.1 0.3 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.1 0.8 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.1 3.6 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 1.9 GO:0000030 mannosyltransferase activity(GO:0000030)
0.1 0.6 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.1 1.1 GO:0089720 caspase binding(GO:0089720)
0.1 1.3 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1 1.7 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 0.3 GO:0000104 succinate dehydrogenase activity(GO:0000104)
0.1 1.5 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.2 GO:0008502 melatonin receptor activity(GO:0008502)
0.1 0.3 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.1 0.2 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.1 0.4 GO:0032552 deoxyribonucleotide binding(GO:0032552)
0.1 0.4 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.1 3.6 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.1 0.8 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.1 0.2 GO:0015068 amidinotransferase activity(GO:0015067) glycine amidinotransferase activity(GO:0015068)
0.1 0.2 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.1 0.4 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.1 0.6 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.1 0.8 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 0.4 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.3 GO:0032089 NACHT domain binding(GO:0032089)
0.0 0.4 GO:0045545 syndecan binding(GO:0045545)
0.0 1.6 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.6 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 1.9 GO:0005123 death receptor binding(GO:0005123)
0.0 0.4 GO:0043295 glutathione binding(GO:0043295)
0.0 1.7 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.1 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.0 0.6 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.0 2.6 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.0 1.2 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.8 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.1 GO:0000994 RNA polymerase III core binding(GO:0000994)
0.0 1.0 GO:0015643 toxic substance binding(GO:0015643)
0.0 5.6 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.2 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.9 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.5 GO:0051425 PTB domain binding(GO:0051425)
0.0 0.7 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.2 GO:0008431 vitamin E binding(GO:0008431)
0.0 0.2 GO:0033592 RNA strand annealing activity(GO:0033592)
0.0 0.1 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
0.0 0.6 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.2 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 0.8 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.6 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0 1.3 GO:0001848 complement binding(GO:0001848)
0.0 0.4 GO:0008428 ribonuclease inhibitor activity(GO:0008428)
0.0 1.0 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 1.0 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.6 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.4 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.0 0.2 GO:0005119 smoothened binding(GO:0005119)
0.0 0.3 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.6 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 1.2 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.9 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 1.0 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.4 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 1.2 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 1.2 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.2 GO:0004137 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.0 1.0 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.2 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.7 GO:0016505 peptidase activator activity involved in apoptotic process(GO:0016505)
0.0 0.5 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 1.3 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.3 GO:0071253 connexin binding(GO:0071253)
0.0 0.3 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.0 1.2 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.5 GO:0035064 methylated histone binding(GO:0035064)
0.0 1.0 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.2 GO:0031013 troponin I binding(GO:0031013)
0.0 0.4 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 0.7 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.9 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.6 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.8 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.5 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 1.5 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 1.2 GO:0003774 motor activity(GO:0003774)
0.0 0.6 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.3 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.3 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.1 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.1 GO:0047522 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.0 0.3 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.0 0.6 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.3 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.7 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.6 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.5 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.1 GO:0004572 mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity(GO:0004572)
0.0 0.9 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 1.7 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.7 GO:0019894 kinesin binding(GO:0019894)
0.0 1.3 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.1 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
0.0 1.8 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.1 GO:0015265 urea channel activity(GO:0015265)
0.0 0.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.5 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 11.1 GO:0019787 ubiquitin-like protein transferase activity(GO:0019787)
0.0 0.3 GO:0031702 angiotensin receptor binding(GO:0031701) type 1 angiotensin receptor binding(GO:0031702)
0.0 0.5 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.5 GO:0047485 protein N-terminus binding(GO:0047485)
0.0 0.5 GO:0005521 lamin binding(GO:0005521)
0.0 2.4 GO:0004386 helicase activity(GO:0004386)
0.0 0.3 GO:0016859 peptidyl-prolyl cis-trans isomerase activity(GO:0003755) cis-trans isomerase activity(GO:0016859)
0.0 0.8 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.1 GO:0031433 telethonin binding(GO:0031433)
0.0 0.5 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.2 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.3 GO:0030275 LRR domain binding(GO:0030275)
0.0 0.0 GO:0097363 protein O-GlcNAc transferase activity(GO:0097363)
0.0 0.6 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.2 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.0 0.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.1 GO:0005502 11-cis retinal binding(GO:0005502)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.9 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.2 3.8 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 8.9 PID AURORA B PATHWAY Aurora B signaling
0.1 0.7 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 4.0 PID NECTIN PATHWAY Nectin adhesion pathway
0.1 2.8 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 2.7 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 2.4 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 2.3 PID PLK1 PATHWAY PLK1 signaling events
0.0 1.5 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.4 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.6 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 1.4 PID MYC PATHWAY C-MYC pathway
0.0 1.1 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 0.4 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.9 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 1.8 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 1.1 PID IFNG PATHWAY IFN-gamma pathway
0.0 1.0 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.5 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.6 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.5 ST GA13 PATHWAY G alpha 13 Pathway
0.0 0.6 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.5 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 1.6 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.2 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.6 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.5 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.8 PID ARF6 PATHWAY Arf6 signaling events
0.0 1.3 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.0 0.4 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.3 REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins
0.1 7.0 REACTOME KINESINS Genes involved in Kinesins
0.1 3.8 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.1 2.5 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 3.6 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.1 2.4 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.1 1.5 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.1 2.5 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 15.2 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 2.6 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1 1.8 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 2.2 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.1 1.9 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 1.5 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 3.0 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 3.4 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.1 1.8 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.1 0.3 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.1 2.8 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.1 0.7 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.1 1.1 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 0.7 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.1 0.8 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.1 2.8 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 2.0 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 1.3 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 1.8 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 1.7 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 1.1 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 1.1 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 1.2 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 1.9 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 3.3 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 1.0 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 1.2 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 1.1 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 1.9 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.4 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.0 0.8 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 0.6 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.7 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.7 REACTOME APC C CDC20 MEDIATED DEGRADATION OF CYCLIN B Genes involved in APC/C:Cdc20 mediated degradation of Cyclin B
0.0 1.0 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.4 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 1.7 REACTOME PI METABOLISM Genes involved in PI Metabolism
0.0 0.3 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.6 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 1.6 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.5 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.5 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.4 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.2 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.6 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 1.7 REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.0 0.4 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.2 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.3 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.3 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.4 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.3 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 0.2 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation