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SARS-CoV-2 Analysis Results (GEO series: GSE147507)
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Results for SPIB
Z-value: 1.63
Motif logo
Transcription factors associated with SPIB
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
SPIB
|
ENSG00000269404.2 | Spi-B transcription factor |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| SPIB | hg19_v2_chr19_+_50922187_50922215 | -0.45 | 4.5e-02 | Click! |
Activity profile of SPIB motif
Sorted Z-values of SPIB motif
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr12_-_15114492 | 6.65 |
ENST00000541546.1
|
ARHGDIB
|
Rho GDP dissociation inhibitor (GDI) beta |
| chr2_+_113885138 | 6.33 |
ENST00000409930.3
|
IL1RN
|
interleukin 1 receptor antagonist |
| chr2_+_233925064 | 6.02 |
ENST00000359570.5
ENST00000538935.1 |
INPP5D
|
inositol polyphosphate-5-phosphatase, 145kDa |
| chr9_-_21995300 | 5.90 |
ENST00000498628.2
|
CDKN2A
|
cyclin-dependent kinase inhibitor 2A |
| chr17_-_39093672 | 5.88 |
ENST00000209718.3
ENST00000436344.3 ENST00000485751.1 |
KRT23
|
keratin 23 (histone deacetylase inducible) |
| chr12_-_15114191 | 5.85 |
ENST00000541380.1
|
ARHGDIB
|
Rho GDP dissociation inhibitor (GDI) beta |
| chr12_-_15114603 | 5.59 |
ENST00000228945.4
|
ARHGDIB
|
Rho GDP dissociation inhibitor (GDI) beta |
| chr22_-_37640277 | 5.42 |
ENST00000401529.3
ENST00000249071.6 |
RAC2
|
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) |
| chr22_-_37640456 | 4.93 |
ENST00000405484.1
ENST00000441619.1 ENST00000406508.1 |
RAC2
|
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) |
| chr3_-_121379739 | 4.44 |
ENST00000428394.2
ENST00000314583.3 |
HCLS1
|
hematopoietic cell-specific Lyn substrate 1 |
| chr19_+_3136115 | 4.09 |
ENST00000262958.3
|
GNA15
|
guanine nucleotide binding protein (G protein), alpha 15 (Gq class) |
| chr16_-_4850471 | 3.90 |
ENST00000592019.1
ENST00000586153.1 |
ROGDI
|
rogdi homolog (Drosophila) |
| chr19_-_51471381 | 3.87 |
ENST00000594641.1
|
KLK6
|
kallikrein-related peptidase 6 |
| chr10_-_98031265 | 3.75 |
ENST00000224337.5
ENST00000371176.2 |
BLNK
|
B-cell linker |
| chr15_+_43886057 | 3.71 |
ENST00000441322.1
ENST00000413657.2 ENST00000453733.1 |
CKMT1B
|
creatine kinase, mitochondrial 1B |
| chr12_-_15114658 | 3.57 |
ENST00000542276.1
|
ARHGDIB
|
Rho GDP dissociation inhibitor (GDI) beta |
| chr15_+_43885252 | 3.32 |
ENST00000453782.1
ENST00000300283.6 ENST00000437924.1 ENST00000450086.2 |
CKMT1B
|
creatine kinase, mitochondrial 1B |
| chr10_-_98031310 | 3.21 |
ENST00000427367.2
ENST00000413476.2 |
BLNK
|
B-cell linker |
| chr15_+_43985084 | 3.20 |
ENST00000434505.1
ENST00000411750.1 |
CKMT1A
|
creatine kinase, mitochondrial 1A |
| chr3_-_176914191 | 3.10 |
ENST00000437738.1
ENST00000424913.1 ENST00000443315.1 |
TBL1XR1
|
transducin (beta)-like 1 X-linked receptor 1 |
| chr6_+_144665237 | 3.08 |
ENST00000421035.2
|
UTRN
|
utrophin |
| chr1_-_156675368 | 3.06 |
ENST00000368222.3
|
CRABP2
|
cellular retinoic acid binding protein 2 |
| chr6_-_47010061 | 3.06 |
ENST00000371253.2
|
GPR110
|
G protein-coupled receptor 110 |
| chr20_-_46415341 | 3.02 |
ENST00000484875.1
ENST00000361612.4 |
SULF2
|
sulfatase 2 |
| chr15_+_43985725 | 3.00 |
ENST00000413453.2
|
CKMT1A
|
creatine kinase, mitochondrial 1A |
| chr1_+_205473784 | 3.00 |
ENST00000478560.1
ENST00000443813.2 |
CDK18
|
cyclin-dependent kinase 18 |
| chr1_+_205473865 | 2.93 |
ENST00000506215.1
ENST00000419301.1 |
CDK18
|
cyclin-dependent kinase 18 |
| chr15_-_45422056 | 2.93 |
ENST00000267803.4
ENST00000559014.1 ENST00000558851.1 ENST00000559988.1 ENST00000558996.1 ENST00000558422.1 ENST00000559226.1 ENST00000558326.1 ENST00000558377.1 ENST00000559644.1 |
DUOXA1
|
dual oxidase maturation factor 1 |
| chr11_-_61101247 | 2.88 |
ENST00000543627.1
|
DDB1
|
damage-specific DNA binding protein 1, 127kDa |
| chr12_-_120663792 | 2.79 |
ENST00000546532.1
ENST00000548912.1 |
PXN
|
paxillin |
| chr1_+_205473720 | 2.78 |
ENST00000429964.2
ENST00000506784.1 ENST00000360066.2 |
CDK18
|
cyclin-dependent kinase 18 |
| chrX_+_56259316 | 2.77 |
ENST00000468660.1
|
KLF8
|
Kruppel-like factor 8 |
| chr6_-_47009996 | 2.74 |
ENST00000371243.2
|
GPR110
|
G protein-coupled receptor 110 |
| chr3_-_9291063 | 2.67 |
ENST00000383836.3
|
SRGAP3
|
SLIT-ROBO Rho GTPase activating protein 3 |
| chr15_+_45422178 | 2.65 |
ENST00000389037.3
ENST00000558322.1 |
DUOX1
|
dual oxidase 1 |
| chr1_+_14075903 | 2.64 |
ENST00000343137.4
ENST00000503842.1 ENST00000407521.3 ENST00000505823.1 |
PRDM2
|
PR domain containing 2, with ZNF domain |
| chr20_-_46415297 | 2.56 |
ENST00000467815.1
ENST00000359930.4 |
SULF2
|
sulfatase 2 |
| chr22_+_17082732 | 2.54 |
ENST00000558085.2
ENST00000592918.1 ENST00000400593.2 ENST00000592107.1 ENST00000426585.1 ENST00000591299.1 |
TPTEP1
|
transmembrane phosphatase with tensin homology pseudogene 1 |
| chr1_+_14075865 | 2.53 |
ENST00000413440.1
|
PRDM2
|
PR domain containing 2, with ZNF domain |
| chr15_+_45422131 | 2.50 |
ENST00000321429.4
|
DUOX1
|
dual oxidase 1 |
| chr5_-_39270725 | 2.47 |
ENST00000512138.1
ENST00000512982.1 ENST00000540520.1 |
FYB
|
FYN binding protein |
| chr11_-_61124776 | 2.46 |
ENST00000542361.1
|
CYB561A3
|
cytochrome b561 family, member A3 |
| chr8_-_101733794 | 2.44 |
ENST00000523555.1
|
PABPC1
|
poly(A) binding protein, cytoplasmic 1 |
| chr2_-_153573887 | 2.43 |
ENST00000493468.2
ENST00000545856.1 |
PRPF40A
|
PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) |
| chr11_+_131240373 | 2.39 |
ENST00000374791.3
ENST00000436745.1 |
NTM
|
neurotrimin |
| chr17_+_7462031 | 2.37 |
ENST00000380535.4
|
TNFSF13
|
tumor necrosis factor (ligand) superfamily, member 13 |
| chr19_-_9420249 | 2.37 |
ENST00000591998.1
|
ZNF699
|
zinc finger protein 699 |
| chr1_-_26680570 | 2.34 |
ENST00000475866.2
|
AIM1L
|
absent in melanoma 1-like |
| chr15_+_43885799 | 2.28 |
ENST00000449946.1
ENST00000417289.1 |
CKMT1B
|
creatine kinase, mitochondrial 1B |
| chr14_+_96968802 | 2.27 |
ENST00000556619.1
ENST00000392990.2 |
PAPOLA
|
poly(A) polymerase alpha |
| chr3_-_16554881 | 2.22 |
ENST00000451036.1
|
RFTN1
|
raftlin, lipid raft linker 1 |
| chr15_+_42651691 | 2.22 |
ENST00000357568.3
ENST00000349748.3 ENST00000318023.7 ENST00000397163.3 |
CAPN3
|
calpain 3, (p94) |
| chr8_+_125860939 | 2.22 |
ENST00000525292.1
ENST00000528090.1 |
LINC00964
|
long intergenic non-protein coding RNA 964 |
| chr4_-_102268708 | 2.21 |
ENST00000525819.1
|
PPP3CA
|
protein phosphatase 3, catalytic subunit, alpha isozyme |
| chr9_+_93564039 | 2.18 |
ENST00000375754.4
ENST00000375751.4 |
SYK
|
spleen tyrosine kinase |
| chrX_+_105936982 | 2.17 |
ENST00000418562.1
|
RNF128
|
ring finger protein 128, E3 ubiquitin protein ligase |
| chr14_+_85996507 | 2.16 |
ENST00000554746.1
|
FLRT2
|
fibronectin leucine rich transmembrane protein 2 |
| chr1_+_43855545 | 2.14 |
ENST00000372450.4
ENST00000310739.4 |
SZT2
|
seizure threshold 2 homolog (mouse) |
| chr6_-_56708459 | 2.13 |
ENST00000370788.2
|
DST
|
dystonin |
| chr7_-_129592471 | 2.11 |
ENST00000473814.2
ENST00000490974.1 |
UBE2H
|
ubiquitin-conjugating enzyme E2H |
| chr4_-_80994619 | 2.10 |
ENST00000404191.1
|
ANTXR2
|
anthrax toxin receptor 2 |
| chr10_+_28822417 | 2.04 |
ENST00000428935.1
ENST00000420266.1 |
WAC
|
WW domain containing adaptor with coiled-coil |
| chr17_+_7461580 | 2.03 |
ENST00000483039.1
ENST00000396542.1 |
TNFSF13
|
tumor necrosis factor (ligand) superfamily, member 13 |
| chr14_+_85996471 | 2.02 |
ENST00000330753.4
|
FLRT2
|
fibronectin leucine rich transmembrane protein 2 |
| chr3_+_121774202 | 1.98 |
ENST00000469710.1
ENST00000493101.1 ENST00000330540.2 ENST00000264468.5 |
CD86
|
CD86 molecule |
| chr6_-_56707943 | 1.92 |
ENST00000370769.4
ENST00000421834.2 ENST00000312431.6 ENST00000361203.3 ENST00000523817.1 |
DST
|
dystonin |
| chr1_+_154193643 | 1.92 |
ENST00000456325.1
|
UBAP2L
|
ubiquitin associated protein 2-like |
| chr6_+_130339710 | 1.91 |
ENST00000526087.1
ENST00000533560.1 ENST00000361794.2 |
L3MBTL3
|
l(3)mbt-like 3 (Drosophila) |
| chr17_+_7461849 | 1.83 |
ENST00000338784.4
|
TNFSF13
|
tumor necrosis factor (ligand) superfamily, member 13 |
| chr19_-_51471362 | 1.83 |
ENST00000376853.4
ENST00000424910.2 |
KLK6
|
kallikrein-related peptidase 6 |
| chr15_-_34629922 | 1.81 |
ENST00000559484.1
ENST00000354181.3 ENST00000558589.1 ENST00000458406.2 |
SLC12A6
|
solute carrier family 12 (potassium/chloride transporter), member 6 |
| chrX_+_105937068 | 1.79 |
ENST00000324342.3
|
RNF128
|
ring finger protein 128, E3 ubiquitin protein ligase |
| chr1_+_154193325 | 1.78 |
ENST00000428931.1
ENST00000441890.1 ENST00000271877.7 ENST00000412596.1 ENST00000368504.1 ENST00000437652.1 |
UBAP2L
|
ubiquitin associated protein 2-like |
| chr1_+_179851999 | 1.77 |
ENST00000527391.1
|
TOR1AIP1
|
torsin A interacting protein 1 |
| chr19_+_16254488 | 1.77 |
ENST00000588246.1
ENST00000593031.1 |
HSH2D
|
hematopoietic SH2 domain containing |
| chr17_+_7461781 | 1.73 |
ENST00000349228.4
|
TNFSF13
|
tumor necrosis factor (ligand) superfamily, member 13 |
| chr6_-_32145861 | 1.73 |
ENST00000336984.6
|
AGPAT1
|
1-acylglycerol-3-phosphate O-acyltransferase 1 |
| chr3_-_176914238 | 1.71 |
ENST00000430069.1
ENST00000428970.1 |
TBL1XR1
|
transducin (beta)-like 1 X-linked receptor 1 |
| chr9_+_124030338 | 1.71 |
ENST00000449773.1
ENST00000432226.1 ENST00000436847.1 ENST00000394353.2 ENST00000449733.1 ENST00000412819.1 ENST00000341272.2 ENST00000373808.2 |
GSN
|
gelsolin |
| chr1_-_175161890 | 1.70 |
ENST00000545251.2
ENST00000423313.1 |
KIAA0040
|
KIAA0040 |
| chr5_+_35856951 | 1.68 |
ENST00000303115.3
ENST00000343305.4 ENST00000506850.1 ENST00000511982.1 |
IL7R
|
interleukin 7 receptor |
| chr1_+_151171012 | 1.66 |
ENST00000349792.5
ENST00000409426.1 ENST00000441902.2 ENST00000368890.4 ENST00000424999.1 ENST00000368888.4 |
PIP5K1A
|
phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| chr5_+_110407390 | 1.65 |
ENST00000344895.3
|
TSLP
|
thymic stromal lymphopoietin |
| chr4_+_30721968 | 1.64 |
ENST00000361762.2
|
PCDH7
|
protocadherin 7 |
| chr12_-_15082050 | 1.62 |
ENST00000540097.1
|
ERP27
|
endoplasmic reticulum protein 27 |
| chr6_-_139308777 | 1.62 |
ENST00000529597.1
ENST00000415951.2 ENST00000367663.4 ENST00000409812.2 |
REPS1
|
RALBP1 associated Eps domain containing 1 |
| chr17_+_7462103 | 1.62 |
ENST00000396545.4
|
TNFSF13
|
tumor necrosis factor (ligand) superfamily, member 13 |
| chr1_+_209941827 | 1.61 |
ENST00000367023.1
|
TRAF3IP3
|
TRAF3 interacting protein 3 |
| chr15_-_34630234 | 1.60 |
ENST00000558667.1
ENST00000561120.1 ENST00000559236.1 ENST00000397702.2 |
SLC12A6
|
solute carrier family 12 (potassium/chloride transporter), member 6 |
| chr9_+_93564191 | 1.60 |
ENST00000375747.1
|
SYK
|
spleen tyrosine kinase |
| chr12_-_51785182 | 1.58 |
ENST00000356317.3
ENST00000603188.1 ENST00000604847.1 ENST00000604506.1 |
GALNT6
|
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6 (GalNAc-T6) |
| chr10_+_106028923 | 1.58 |
ENST00000338595.2
|
GSTO2
|
glutathione S-transferase omega 2 |
| chr5_+_65892174 | 1.55 |
ENST00000404260.3
ENST00000403625.2 ENST00000406374.1 |
MAST4
|
microtubule associated serine/threonine kinase family member 4 |
| chr16_+_30194916 | 1.55 |
ENST00000570045.1
ENST00000565497.1 ENST00000570244.1 |
CORO1A
|
coronin, actin binding protein, 1A |
| chr9_+_109625378 | 1.53 |
ENST00000277225.5
ENST00000457913.1 ENST00000472574.1 |
ZNF462
|
zinc finger protein 462 |
| chr12_+_25205446 | 1.52 |
ENST00000557489.1
ENST00000354454.3 ENST00000536173.1 |
LRMP
|
lymphoid-restricted membrane protein |
| chr10_+_11206925 | 1.51 |
ENST00000354440.2
ENST00000315874.4 ENST00000427450.1 |
CELF2
|
CUGBP, Elav-like family member 2 |
| chr10_+_106028605 | 1.50 |
ENST00000450629.2
|
GSTO2
|
glutathione S-transferase omega 2 |
| chr15_+_59279851 | 1.49 |
ENST00000348370.4
ENST00000434298.1 ENST00000559160.1 |
RNF111
|
ring finger protein 111 |
| chr2_-_208031943 | 1.48 |
ENST00000421199.1
ENST00000457962.1 |
KLF7
|
Kruppel-like factor 7 (ubiquitous) |
| chr1_+_40505891 | 1.48 |
ENST00000372797.3
ENST00000372802.1 ENST00000449311.1 |
CAP1
|
CAP, adenylate cyclase-associated protein 1 (yeast) |
| chr8_+_98656693 | 1.44 |
ENST00000519934.1
|
MTDH
|
metadherin |
| chr1_+_3541543 | 1.41 |
ENST00000378344.2
ENST00000344579.5 |
TPRG1L
|
tumor protein p63 regulated 1-like |
| chr12_-_9102224 | 1.41 |
ENST00000543845.1
ENST00000544245.1 |
M6PR
|
mannose-6-phosphate receptor (cation dependent) |
| chr4_-_87281224 | 1.40 |
ENST00000395169.3
ENST00000395161.2 |
MAPK10
|
mitogen-activated protein kinase 10 |
| chr6_-_41254403 | 1.38 |
ENST00000589614.1
ENST00000334475.6 ENST00000591620.1 ENST00000244709.4 |
TREM1
|
triggering receptor expressed on myeloid cells 1 |
| chr11_-_116658758 | 1.38 |
ENST00000227322.3
|
ZNF259
|
zinc finger protein 259 |
| chr11_-_116658695 | 1.37 |
ENST00000429220.1
ENST00000444935.1 |
ZNF259
|
zinc finger protein 259 |
| chr10_+_129785536 | 1.37 |
ENST00000419012.2
|
PTPRE
|
protein tyrosine phosphatase, receptor type, E |
| chr1_+_112016414 | 1.36 |
ENST00000343534.5
ENST00000369718.3 |
C1orf162
|
chromosome 1 open reading frame 162 |
| chr11_-_61124711 | 1.35 |
ENST00000536915.1
|
CYB561A3
|
cytochrome b561 family, member A3 |
| chr2_+_157292859 | 1.34 |
ENST00000438166.2
|
GPD2
|
glycerol-3-phosphate dehydrogenase 2 (mitochondrial) |
| chr12_+_25205666 | 1.32 |
ENST00000547044.1
|
LRMP
|
lymphoid-restricted membrane protein |
| chr9_+_93589734 | 1.31 |
ENST00000375746.1
|
SYK
|
spleen tyrosine kinase |
| chr8_-_101734308 | 1.27 |
ENST00000519004.1
ENST00000519363.1 ENST00000520142.1 |
PABPC1
|
poly(A) binding protein, cytoplasmic 1 |
| chr1_+_179851893 | 1.26 |
ENST00000531630.2
|
TOR1AIP1
|
torsin A interacting protein 1 |
| chr10_+_28822636 | 1.24 |
ENST00000442148.1
ENST00000448193.1 |
WAC
|
WW domain containing adaptor with coiled-coil |
| chr7_-_135662056 | 1.23 |
ENST00000393085.3
ENST00000435723.1 |
MTPN
|
myotrophin |
| chr21_-_32716556 | 1.22 |
ENST00000455508.1
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1 |
| chr4_-_146859787 | 1.21 |
ENST00000508784.1
|
ZNF827
|
zinc finger protein 827 |
| chr11_+_27062272 | 1.20 |
ENST00000529202.1
ENST00000533566.1 |
BBOX1
|
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 |
| chr10_+_11207438 | 1.20 |
ENST00000609692.1
ENST00000354897.3 |
CELF2
|
CUGBP, Elav-like family member 2 |
| chr4_-_102268484 | 1.20 |
ENST00000394853.4
|
PPP3CA
|
protein phosphatase 3, catalytic subunit, alpha isozyme |
| chr1_-_54879140 | 1.18 |
ENST00000525990.1
|
SSBP3
|
single stranded DNA binding protein 3 |
| chr6_+_142468383 | 1.18 |
ENST00000367621.1
ENST00000452973.2 |
VTA1
|
vesicle (multivesicular body) trafficking 1 |
| chr12_+_32638897 | 1.18 |
ENST00000531134.1
|
FGD4
|
FYVE, RhoGEF and PH domain containing 4 |
| chr15_+_50716576 | 1.18 |
ENST00000560297.1
ENST00000307179.4 ENST00000396444.3 ENST00000433963.1 ENST00000425032.3 |
USP8
|
ubiquitin specific peptidase 8 |
| chr6_-_139309378 | 1.17 |
ENST00000450536.2
ENST00000258062.5 |
REPS1
|
RALBP1 associated Eps domain containing 1 |
| chr4_-_87281196 | 1.17 |
ENST00000359221.3
|
MAPK10
|
mitogen-activated protein kinase 10 |
| chr1_-_38325256 | 1.17 |
ENST00000373036.4
|
MTF1
|
metal-regulatory transcription factor 1 |
| chr11_-_18656028 | 1.16 |
ENST00000336349.5
|
SPTY2D1
|
SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae) |
| chr8_-_101962777 | 1.15 |
ENST00000395951.3
|
YWHAZ
|
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta |
| chr2_-_26101314 | 1.14 |
ENST00000336112.4
ENST00000272341.4 |
ASXL2
|
additional sex combs like 2 (Drosophila) |
| chr10_-_92617671 | 1.14 |
ENST00000371721.3
|
HTR7
|
5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled |
| chr6_+_42952237 | 1.13 |
ENST00000485511.1
ENST00000394110.3 ENST00000472118.1 ENST00000461010.1 |
PPP2R5D
|
protein phosphatase 2, regulatory subunit B', delta |
| chr2_-_231084617 | 1.11 |
ENST00000409815.2
|
SP110
|
SP110 nuclear body protein |
| chr2_+_138721850 | 1.11 |
ENST00000329366.4
ENST00000280097.3 |
HNMT
|
histamine N-methyltransferase |
| chr9_+_104296243 | 1.11 |
ENST00000466817.1
|
RNF20
|
ring finger protein 20, E3 ubiquitin protein ligase |
| chr12_+_25205568 | 1.10 |
ENST00000548766.1
ENST00000556887.1 |
LRMP
|
lymphoid-restricted membrane protein |
| chr17_-_4642429 | 1.09 |
ENST00000573123.1
|
CXCL16
|
chemokine (C-X-C motif) ligand 16 |
| chr19_-_15344243 | 1.08 |
ENST00000602233.1
|
EPHX3
|
epoxide hydrolase 3 |
| chr5_-_124084493 | 1.08 |
ENST00000509799.1
|
ZNF608
|
zinc finger protein 608 |
| chr4_+_159727222 | 1.08 |
ENST00000512986.1
|
FNIP2
|
folliculin interacting protein 2 |
| chr1_+_39456895 | 1.08 |
ENST00000432648.3
ENST00000446189.2 ENST00000372984.4 |
AKIRIN1
|
akirin 1 |
| chr9_-_21995249 | 1.08 |
ENST00000494262.1
|
CDKN2A
|
cyclin-dependent kinase inhibitor 2A |
| chr17_+_65374075 | 1.08 |
ENST00000581322.1
|
PITPNC1
|
phosphatidylinositol transfer protein, cytoplasmic 1 |
| chr7_-_102213030 | 1.06 |
ENST00000511313.1
ENST00000513438.1 ENST00000513506.1 |
POLR2J3
|
polymerase (RNA) II (DNA directed) polypeptide J3 |
| chr20_+_31823792 | 1.05 |
ENST00000375413.4
ENST00000354297.4 ENST00000375422.2 |
BPIFA1
|
BPI fold containing family A, member 1 |
| chr7_-_129592700 | 1.03 |
ENST00000472396.1
ENST00000355621.3 |
UBE2H
|
ubiquitin-conjugating enzyme E2H |
| chr2_-_231084820 | 1.02 |
ENST00000258382.5
ENST00000338556.3 |
SP110
|
SP110 nuclear body protein |
| chr17_+_7461613 | 1.01 |
ENST00000438470.1
ENST00000436057.1 |
TNFSF13
|
tumor necrosis factor (ligand) superfamily, member 13 |
| chr10_-_977564 | 1.01 |
ENST00000406525.2
|
LARP4B
|
La ribonucleoprotein domain family, member 4B |
| chr12_-_80083807 | 1.01 |
ENST00000551712.1
|
PAWR
|
PRKC, apoptosis, WT1, regulator |
| chr1_-_145039771 | 1.00 |
ENST00000493130.2
ENST00000532801.1 ENST00000478649.2 |
PDE4DIP
|
phosphodiesterase 4D interacting protein |
| chr12_+_25205155 | 0.99 |
ENST00000550945.1
|
LRMP
|
lymphoid-restricted membrane protein |
| chr7_-_152133059 | 0.99 |
ENST00000262189.6
ENST00000355193.2 |
KMT2C
|
lysine (K)-specific methyltransferase 2C |
| chr1_+_43855560 | 0.98 |
ENST00000562955.1
|
SZT2
|
seizure threshold 2 homolog (mouse) |
| chr3_+_28390637 | 0.97 |
ENST00000420223.1
ENST00000383768.2 |
ZCWPW2
|
zinc finger, CW type with PWWP domain 2 |
| chr1_-_45956822 | 0.96 |
ENST00000372086.3
ENST00000341771.6 |
TESK2
|
testis-specific kinase 2 |
| chr1_+_161676739 | 0.96 |
ENST00000236938.6
ENST00000367959.2 ENST00000546024.1 ENST00000540521.1 ENST00000367949.2 ENST00000350710.3 ENST00000540926.1 |
FCRLA
|
Fc receptor-like A |
| chr9_-_35618364 | 0.95 |
ENST00000378431.1
ENST00000378430.3 ENST00000259633.4 |
CD72
|
CD72 molecule |
| chr10_-_79789291 | 0.95 |
ENST00000372371.3
|
POLR3A
|
polymerase (RNA) III (DNA directed) polypeptide A, 155kDa |
| chr1_+_161677034 | 0.94 |
ENST00000349527.4
ENST00000309691.6 ENST00000294796.4 ENST00000367953.3 ENST00000367950.1 |
FCRLA
|
Fc receptor-like A |
| chr6_+_15246501 | 0.94 |
ENST00000341776.2
|
JARID2
|
jumonji, AT rich interactive domain 2 |
| chr14_-_50319482 | 0.92 |
ENST00000546046.1
ENST00000555970.1 ENST00000554626.1 ENST00000545773.1 ENST00000556672.1 |
NEMF
|
nuclear export mediator factor |
| chr3_+_121796697 | 0.92 |
ENST00000482356.1
ENST00000393627.2 |
CD86
|
CD86 molecule |
| chr15_-_34610962 | 0.91 |
ENST00000290209.5
|
SLC12A6
|
solute carrier family 12 (potassium/chloride transporter), member 6 |
| chr2_-_8723918 | 0.91 |
ENST00000454224.1
|
AC011747.4
|
AC011747.4 |
| chr4_+_159727272 | 0.91 |
ENST00000379346.3
|
FNIP2
|
folliculin interacting protein 2 |
| chr17_+_28443799 | 0.89 |
ENST00000584423.1
ENST00000247026.5 |
NSRP1
|
nuclear speckle splicing regulatory protein 1 |
| chr20_+_44486246 | 0.89 |
ENST00000255152.2
ENST00000454862.2 |
ZSWIM3
|
zinc finger, SWIM-type containing 3 |
| chr10_-_103578162 | 0.88 |
ENST00000361464.3
ENST00000357797.5 ENST00000370094.3 |
MGEA5
|
meningioma expressed antigen 5 (hyaluronidase) |
| chr1_+_78383813 | 0.87 |
ENST00000342754.5
|
NEXN
|
nexilin (F actin binding protein) |
| chr14_-_74416829 | 0.87 |
ENST00000534936.1
|
FAM161B
|
family with sequence similarity 161, member B |
| chr2_-_231084659 | 0.86 |
ENST00000258381.6
ENST00000358662.4 ENST00000455674.1 ENST00000392048.3 |
SP110
|
SP110 nuclear body protein |
| chr17_+_75136980 | 0.86 |
ENST00000585618.1
ENST00000413679.2 |
SEC14L1
|
SEC14-like 1 (S. cerevisiae) |
| chr9_+_104296163 | 0.85 |
ENST00000374819.2
ENST00000479306.1 |
RNF20
|
ring finger protein 20, E3 ubiquitin protein ligase |
| chr16_-_19725899 | 0.85 |
ENST00000567367.1
|
KNOP1
|
lysine-rich nucleolar protein 1 |
| chr1_-_17380630 | 0.84 |
ENST00000375499.3
|
SDHB
|
succinate dehydrogenase complex, subunit B, iron sulfur (Ip) |
| chr3_-_179169330 | 0.84 |
ENST00000232564.3
|
GNB4
|
guanine nucleotide binding protein (G protein), beta polypeptide 4 |
| chr1_+_183441618 | 0.84 |
ENST00000507691.2
ENST00000508461.1 ENST00000419169.1 ENST00000347615.2 ENST00000507469.1 ENST00000515829.2 |
SMG7
|
SMG7 nonsense mediated mRNA decay factor |
| chr6_+_26251835 | 0.83 |
ENST00000356350.2
|
HIST1H2BH
|
histone cluster 1, H2bh |
| chr8_-_101734170 | 0.83 |
ENST00000522387.1
ENST00000518196.1 |
PABPC1
|
poly(A) binding protein, cytoplasmic 1 |
| chr1_+_183441500 | 0.82 |
ENST00000456731.2
|
SMG7
|
SMG7 nonsense mediated mRNA decay factor |
| chr2_-_180871780 | 0.81 |
ENST00000410053.3
ENST00000295749.6 ENST00000404136.2 |
CWC22
|
CWC22 spliceosome-associated protein homolog (S. cerevisiae) |
| chr3_+_128598433 | 0.80 |
ENST00000308982.7
ENST00000514336.1 |
ACAD9
|
acyl-CoA dehydrogenase family, member 9 |
| chr12_+_25205628 | 0.80 |
ENST00000554942.1
|
LRMP
|
lymphoid-restricted membrane protein |
| chr17_+_75137034 | 0.80 |
ENST00000436233.4
ENST00000443798.4 |
SEC14L1
|
SEC14-like 1 (S. cerevisiae) |
| chr1_-_20834586 | 0.79 |
ENST00000264198.3
|
MUL1
|
mitochondrial E3 ubiquitin protein ligase 1 |
| chr5_+_64859066 | 0.78 |
ENST00000261308.5
ENST00000535264.1 ENST00000538977.1 |
PPWD1
|
peptidylprolyl isomerase domain and WD repeat containing 1 |
| chr14_+_67291158 | 0.77 |
ENST00000555456.1
|
GPHN
|
gephyrin |
| chr8_-_131028869 | 0.77 |
ENST00000518283.1
ENST00000519110.1 |
FAM49B
|
family with sequence similarity 49, member B |
| chrX_+_123094672 | 0.76 |
ENST00000354548.5
ENST00000458700.1 |
STAG2
|
stromal antigen 2 |
| chr6_-_144385698 | 0.75 |
ENST00000444202.1
ENST00000437412.1 |
PLAGL1
|
pleiomorphic adenoma gene-like 1 |
| chr1_+_117544366 | 0.75 |
ENST00000256652.4
ENST00000369470.1 |
CD101
|
CD101 molecule |
| chr15_-_65810042 | 0.75 |
ENST00000321147.6
|
DPP8
|
dipeptidyl-peptidase 8 |
| chrX_+_11776410 | 0.74 |
ENST00000361672.2
|
MSL3
|
male-specific lethal 3 homolog (Drosophila) |
| chr1_+_24018269 | 0.74 |
ENST00000374550.3
|
RPL11
|
ribosomal protein L11 |
| chr3_+_32433363 | 0.73 |
ENST00000465248.1
|
CMTM7
|
CKLF-like MARVEL transmembrane domain containing 7 |
| chr10_+_129785574 | 0.73 |
ENST00000430713.2
ENST00000471218.1 |
PTPRE
|
protein tyrosine phosphatase, receptor type, E |
Network of associatons between targets according to the STRING database.
First level regulatory network of SPIB
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.1 | 21.7 | GO:0071461 | cellular response to redox state(GO:0071461) |
| 1.3 | 6.6 | GO:0045659 | regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659) |
| 1.3 | 5.1 | GO:0071226 | response to molecule of fungal origin(GO:0002238) cellular response to molecule of fungal origin(GO:0071226) |
| 1.0 | 3.1 | GO:0045404 | positive regulation of interleukin-4 biosynthetic process(GO:0045404) |
| 1.0 | 5.0 | GO:0071477 | hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477) |
| 1.0 | 3.9 | GO:1905205 | positive regulation of connective tissue replacement(GO:1905205) |
| 0.9 | 10.4 | GO:0060753 | regulation of mast cell chemotaxis(GO:0060753) |
| 0.9 | 10.6 | GO:0048298 | positive regulation of isotype switching to IgA isotypes(GO:0048298) |
| 0.9 | 5.2 | GO:0042335 | cuticle development(GO:0042335) |
| 0.8 | 3.3 | GO:0071894 | histone H2B conserved C-terminal lysine ubiquitination(GO:0071894) |
| 0.8 | 5.6 | GO:0014846 | esophagus smooth muscle contraction(GO:0014846) |
| 0.7 | 6.3 | GO:2000660 | negative regulation of interleukin-1-mediated signaling pathway(GO:2000660) |
| 0.7 | 4.2 | GO:0061343 | cell adhesion involved in heart morphogenesis(GO:0061343) |
| 0.7 | 3.5 | GO:0046726 | positive regulation by virus of viral protein levels in host cell(GO:0046726) |
| 0.6 | 7.0 | GO:0035986 | senescence-associated heterochromatin focus assembly(GO:0035986) |
| 0.5 | 3.7 | GO:0061484 | hematopoietic stem cell homeostasis(GO:0061484) |
| 0.5 | 4.1 | GO:0007207 | phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207) |
| 0.5 | 1.4 | GO:0032707 | negative regulation of interleukin-23 production(GO:0032707) |
| 0.4 | 3.1 | GO:1901668 | regulation of superoxide dismutase activity(GO:1901668) |
| 0.4 | 1.2 | GO:2000744 | anterior head development(GO:0097065) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744) |
| 0.4 | 1.1 | GO:0007198 | adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198) |
| 0.4 | 4.5 | GO:2000622 | regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623) |
| 0.4 | 6.2 | GO:0006600 | creatine metabolic process(GO:0006600) |
| 0.3 | 1.7 | GO:1903906 | plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906) |
| 0.3 | 2.6 | GO:2000609 | regulation of thyroid hormone generation(GO:2000609) |
| 0.3 | 4.8 | GO:0060613 | fat pad development(GO:0060613) |
| 0.3 | 2.2 | GO:0014718 | positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718) |
| 0.3 | 4.9 | GO:0030854 | positive regulation of granulocyte differentiation(GO:0030854) |
| 0.3 | 1.5 | GO:0032796 | uropod organization(GO:0032796) |
| 0.3 | 4.1 | GO:0071763 | nuclear membrane organization(GO:0071763) |
| 0.3 | 4.0 | GO:1904352 | positive regulation of protein catabolic process in the vacuole(GO:1904352) |
| 0.3 | 5.7 | GO:0016540 | protein autoprocessing(GO:0016540) |
| 0.3 | 1.3 | GO:0006127 | glycerophosphate shuttle(GO:0006127) |
| 0.3 | 1.1 | GO:0044407 | biofilm formation(GO:0042710) single-species biofilm formation(GO:0044010) single-species biofilm formation in or on host organism(GO:0044407) regulation of single-species biofilm formation(GO:1900190) negative regulation of single-species biofilm formation(GO:1900191) regulation of single-species biofilm formation in or on host organism(GO:1900228) negative regulation of single-species biofilm formation in or on host organism(GO:1900229) |
| 0.3 | 0.8 | GO:0042040 | molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579) |
| 0.3 | 4.1 | GO:0008090 | retrograde axonal transport(GO:0008090) |
| 0.2 | 1.0 | GO:1902683 | regulation of receptor localization to synapse(GO:1902683) |
| 0.2 | 3.1 | GO:0090487 | toxin catabolic process(GO:0009407) secondary metabolite catabolic process(GO:0090487) |
| 0.2 | 2.8 | GO:0002457 | T cell antigen processing and presentation(GO:0002457) |
| 0.2 | 2.3 | GO:2001168 | regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168) |
| 0.2 | 1.2 | GO:0010847 | regulation of chromatin assembly(GO:0010847) |
| 0.2 | 1.4 | GO:0070945 | neutrophil mediated killing of gram-negative bacterium(GO:0070945) |
| 0.2 | 0.7 | GO:1903371 | establishment of protein localization to endoplasmic reticulum membrane(GO:0097051) regulation of endoplasmic reticulum tubular network organization(GO:1903371) |
| 0.2 | 0.6 | GO:0061485 | memory T cell proliferation(GO:0061485) |
| 0.2 | 0.6 | GO:0072356 | chromosome passenger complex localization to kinetochore(GO:0072356) |
| 0.2 | 1.2 | GO:0001692 | histamine metabolic process(GO:0001692) |
| 0.2 | 3.1 | GO:0048672 | positive regulation of collateral sprouting(GO:0048672) |
| 0.2 | 0.7 | GO:2000434 | regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435) |
| 0.2 | 2.6 | GO:0007258 | JUN phosphorylation(GO:0007258) |
| 0.2 | 0.6 | GO:0002337 | B-1a B cell differentiation(GO:0002337) |
| 0.2 | 1.2 | GO:1903977 | positive regulation of glial cell migration(GO:1903977) |
| 0.2 | 0.5 | GO:0045083 | negative regulation of interleukin-12 biosynthetic process(GO:0045083) |
| 0.2 | 1.0 | GO:0042986 | positive regulation of amyloid precursor protein biosynthetic process(GO:0042986) |
| 0.2 | 1.5 | GO:0030579 | ubiquitin-dependent SMAD protein catabolic process(GO:0030579) |
| 0.2 | 3.1 | GO:0014877 | response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894) |
| 0.2 | 3.9 | GO:0008340 | determination of adult lifespan(GO:0008340) |
| 0.2 | 1.2 | GO:2000812 | regulation of barbed-end actin filament capping(GO:2000812) |
| 0.1 | 1.9 | GO:0045329 | carnitine biosynthetic process(GO:0045329) |
| 0.1 | 1.5 | GO:0051902 | negative regulation of mitochondrial depolarization(GO:0051902) |
| 0.1 | 0.6 | GO:0015670 | carbon dioxide transport(GO:0015670) |
| 0.1 | 0.6 | GO:2001045 | negative regulation of integrin-mediated signaling pathway(GO:2001045) |
| 0.1 | 1.9 | GO:0043249 | erythrocyte maturation(GO:0043249) |
| 0.1 | 0.9 | GO:0061198 | fungiform papilla formation(GO:0061198) |
| 0.1 | 1.6 | GO:0033299 | secretion of lysosomal enzymes(GO:0033299) |
| 0.1 | 0.5 | GO:1990737 | response to manganese-induced endoplasmic reticulum stress(GO:1990737) |
| 0.1 | 0.8 | GO:1901526 | negative regulation of mitochondrial fusion(GO:0010637) positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925) |
| 0.1 | 1.7 | GO:0039536 | negative regulation of RIG-I signaling pathway(GO:0039536) |
| 0.1 | 0.7 | GO:0060800 | regulation of cell differentiation involved in embryonic placenta development(GO:0060800) |
| 0.1 | 0.7 | GO:0060040 | retinal bipolar neuron differentiation(GO:0060040) |
| 0.1 | 2.8 | GO:0007172 | signal complex assembly(GO:0007172) |
| 0.1 | 1.7 | GO:0033089 | positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400) |
| 0.1 | 1.4 | GO:0032876 | negative regulation of DNA endoreduplication(GO:0032876) |
| 0.1 | 0.5 | GO:0032497 | detection of lipopolysaccharide(GO:0032497) |
| 0.1 | 1.3 | GO:1904896 | ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903) |
| 0.1 | 0.5 | GO:0038018 | Wnt receptor catabolic process(GO:0038018) |
| 0.1 | 1.4 | GO:0034058 | endosomal vesicle fusion(GO:0034058) |
| 0.1 | 1.0 | GO:0070973 | protein localization to endoplasmic reticulum exit site(GO:0070973) |
| 0.1 | 0.2 | GO:1905051 | regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053) |
| 0.1 | 0.1 | GO:0050849 | negative regulation of calcium-mediated signaling(GO:0050849) |
| 0.1 | 0.6 | GO:0031507 | heterochromatin assembly(GO:0031507) |
| 0.1 | 0.5 | GO:0039019 | pronephric nephron development(GO:0039019) |
| 0.1 | 0.3 | GO:0033625 | positive regulation of integrin activation(GO:0033625) |
| 0.1 | 0.8 | GO:0006105 | succinate metabolic process(GO:0006105) |
| 0.1 | 0.6 | GO:2000158 | positive regulation of ubiquitin-specific protease activity(GO:2000158) |
| 0.1 | 0.7 | GO:0075525 | viral translational termination-reinitiation(GO:0075525) |
| 0.1 | 3.6 | GO:0006376 | mRNA splice site selection(GO:0006376) |
| 0.1 | 1.1 | GO:0090168 | Golgi reassembly(GO:0090168) |
| 0.1 | 1.6 | GO:0035360 | positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360) |
| 0.1 | 1.1 | GO:2000675 | negative regulation of type B pancreatic cell apoptotic process(GO:2000675) |
| 0.1 | 2.9 | GO:0006607 | NLS-bearing protein import into nucleus(GO:0006607) |
| 0.1 | 0.3 | GO:0044027 | hypermethylation of CpG island(GO:0044027) |
| 0.1 | 0.7 | GO:0035973 | aggrephagy(GO:0035973) |
| 0.1 | 0.4 | GO:0030879 | mammary gland development(GO:0030879) |
| 0.1 | 0.4 | GO:0019805 | quinolinate biosynthetic process(GO:0019805) |
| 0.1 | 0.1 | GO:0061183 | dermatome development(GO:0061054) regulation of dermatome development(GO:0061183) |
| 0.1 | 3.1 | GO:0070979 | protein K11-linked ubiquitination(GO:0070979) |
| 0.1 | 0.3 | GO:0033523 | histone H2B ubiquitination(GO:0033523) |
| 0.1 | 2.8 | GO:0031440 | regulation of mRNA 3'-end processing(GO:0031440) |
| 0.0 | 0.8 | GO:0001955 | blood vessel maturation(GO:0001955) |
| 0.0 | 1.7 | GO:0043968 | histone H2A acetylation(GO:0043968) |
| 0.0 | 0.4 | GO:0035469 | determination of pancreatic left/right asymmetry(GO:0035469) |
| 0.0 | 0.9 | GO:0051574 | positive regulation of histone H3-K9 methylation(GO:0051574) |
| 0.0 | 0.5 | GO:2001300 | lipoxin metabolic process(GO:2001300) |
| 0.0 | 0.4 | GO:0019471 | peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) |
| 0.0 | 0.2 | GO:1902725 | negative regulation of satellite cell differentiation(GO:1902725) |
| 0.0 | 1.2 | GO:0006044 | N-acetylglucosamine metabolic process(GO:0006044) |
| 0.0 | 0.9 | GO:0048739 | cardiac muscle fiber development(GO:0048739) |
| 0.0 | 6.9 | GO:0006903 | vesicle targeting(GO:0006903) |
| 0.0 | 0.2 | GO:0043686 | co-translational protein modification(GO:0043686) |
| 0.0 | 0.4 | GO:1901341 | activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341) |
| 0.0 | 0.5 | GO:0035826 | rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680) |
| 0.0 | 0.2 | GO:0019626 | short-chain fatty acid catabolic process(GO:0019626) |
| 0.0 | 0.2 | GO:1904566 | response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566) |
| 0.0 | 6.0 | GO:0070268 | cornification(GO:0070268) |
| 0.0 | 2.4 | GO:0008038 | neuron recognition(GO:0008038) |
| 0.0 | 1.2 | GO:0071108 | protein K48-linked deubiquitination(GO:0071108) |
| 0.0 | 1.9 | GO:0072661 | protein targeting to plasma membrane(GO:0072661) |
| 0.0 | 0.2 | GO:0035093 | spermatogenesis, exchange of chromosomal proteins(GO:0035093) |
| 0.0 | 0.2 | GO:1900169 | regulation of glucocorticoid mediated signaling pathway(GO:1900169) |
| 0.0 | 0.3 | GO:1990504 | dense core granule exocytosis(GO:1990504) |
| 0.0 | 0.7 | GO:0034975 | protein folding in endoplasmic reticulum(GO:0034975) |
| 0.0 | 0.6 | GO:0001649 | osteoblast differentiation(GO:0001649) |
| 0.0 | 0.6 | GO:0098719 | sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118) |
| 0.0 | 1.5 | GO:0043392 | negative regulation of DNA binding(GO:0043392) |
| 0.0 | 1.5 | GO:0007190 | activation of adenylate cyclase activity(GO:0007190) |
| 0.0 | 0.4 | GO:0060022 | hard palate development(GO:0060022) |
| 0.0 | 0.3 | GO:0071351 | interleukin-18-mediated signaling pathway(GO:0035655) cellular response to interleukin-18(GO:0071351) |
| 0.0 | 1.6 | GO:1901998 | toxin transport(GO:1901998) |
| 0.0 | 3.9 | GO:0030183 | B cell differentiation(GO:0030183) |
| 0.0 | 1.7 | GO:0031325 | positive regulation of cellular metabolic process(GO:0031325) |
| 0.0 | 0.6 | GO:0033169 | histone H3-K9 demethylation(GO:0033169) |
| 0.0 | 0.8 | GO:0009299 | mRNA transcription(GO:0009299) |
| 0.0 | 1.8 | GO:0015914 | phospholipid transport(GO:0015914) |
| 0.0 | 0.6 | GO:0000042 | protein targeting to Golgi(GO:0000042) |
| 0.0 | 0.0 | GO:0071287 | cellular response to manganese ion(GO:0071287) |
| 0.0 | 1.0 | GO:1903146 | regulation of mitophagy(GO:1903146) |
| 0.0 | 0.2 | GO:0090481 | pyrimidine nucleotide-sugar transmembrane transport(GO:0090481) |
| 0.0 | 0.6 | GO:0006487 | protein N-linked glycosylation(GO:0006487) |
| 0.0 | 0.1 | GO:0035878 | nail development(GO:0035878) |
| 0.0 | 1.8 | GO:0016266 | O-glycan processing(GO:0016266) |
| 0.0 | 0.3 | GO:0071474 | cellular hyperosmotic response(GO:0071474) |
| 0.0 | 1.1 | GO:0051568 | histone H3-K4 methylation(GO:0051568) |
| 0.0 | 1.4 | GO:0007004 | telomere maintenance via telomerase(GO:0007004) |
| 0.0 | 1.1 | GO:0046686 | response to cadmium ion(GO:0046686) |
| 0.0 | 0.6 | GO:1904837 | beta-catenin-TCF complex assembly(GO:1904837) |
| 0.0 | 0.3 | GO:0000028 | ribosomal small subunit assembly(GO:0000028) |
| 0.0 | 0.8 | GO:0000413 | protein peptidyl-prolyl isomerization(GO:0000413) |
| 0.0 | 0.5 | GO:2000369 | regulation of clathrin-mediated endocytosis(GO:2000369) |
| 0.0 | 1.3 | GO:0032465 | regulation of cytokinesis(GO:0032465) |
| 0.0 | 0.0 | GO:0061470 | T follicular helper cell differentiation(GO:0061470) |
| 0.0 | 0.2 | GO:0001574 | ganglioside biosynthetic process(GO:0001574) |
| 0.0 | 0.8 | GO:0021762 | substantia nigra development(GO:0021762) |
| 0.0 | 0.4 | GO:0001525 | angiogenesis(GO:0001525) |
| 0.0 | 0.6 | GO:0046627 | negative regulation of insulin receptor signaling pathway(GO:0046627) |
| 0.0 | 0.3 | GO:0034332 | adherens junction organization(GO:0034332) |
| 0.0 | 1.1 | GO:0048024 | regulation of mRNA splicing, via spliceosome(GO:0048024) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 4.1 | GO:0031673 | H zone(GO:0031673) |
| 0.6 | 4.4 | GO:0019815 | B cell receptor complex(GO:0019815) |
| 0.6 | 1.9 | GO:0046696 | lipopolysaccharide receptor complex(GO:0046696) |
| 0.6 | 7.0 | GO:0035985 | senescence-associated heterochromatin focus(GO:0035985) |
| 0.4 | 3.1 | GO:1990130 | Iml1 complex(GO:1990130) |
| 0.4 | 3.7 | GO:0005955 | calcineurin complex(GO:0005955) |
| 0.3 | 3.5 | GO:0031465 | Cul4B-RING E3 ubiquitin ligase complex(GO:0031465) |
| 0.2 | 2.3 | GO:0033503 | HULC complex(GO:0033503) |
| 0.2 | 0.8 | GO:0045281 | mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283) |
| 0.2 | 0.8 | GO:0071006 | U2-type catalytic step 1 spliceosome(GO:0071006) |
| 0.2 | 1.0 | GO:0031515 | tRNA (m1A) methyltransferase complex(GO:0031515) |
| 0.2 | 1.3 | GO:0009331 | glycerol-3-phosphate dehydrogenase complex(GO:0009331) |
| 0.2 | 0.7 | GO:0097635 | extrinsic component of autophagosome membrane(GO:0097635) |
| 0.2 | 3.1 | GO:0070938 | contractile ring(GO:0070938) |
| 0.2 | 0.5 | GO:0043614 | multi-eIF complex(GO:0043614) translation preinitiation complex(GO:0070993) glial limiting end-foot(GO:0097451) |
| 0.1 | 1.5 | GO:0042788 | polysomal ribosome(GO:0042788) |
| 0.1 | 1.4 | GO:0033263 | CORVET complex(GO:0033263) |
| 0.1 | 1.0 | GO:0071256 | Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256) |
| 0.1 | 4.5 | GO:1990124 | messenger ribonucleoprotein complex(GO:1990124) |
| 0.1 | 1.6 | GO:0072487 | MSL complex(GO:0072487) |
| 0.1 | 1.4 | GO:0046581 | intercellular canaliculus(GO:0046581) |
| 0.1 | 1.7 | GO:0030478 | actin cap(GO:0030478) |
| 0.1 | 1.2 | GO:0031313 | extrinsic component of endosome membrane(GO:0031313) |
| 0.1 | 11.0 | GO:0030670 | phagocytic vesicle membrane(GO:0030670) |
| 0.1 | 0.4 | GO:0016222 | procollagen-proline 4-dioxygenase complex(GO:0016222) |
| 0.1 | 1.8 | GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671) |
| 0.1 | 0.6 | GO:0070847 | core mediator complex(GO:0070847) |
| 0.1 | 1.0 | GO:0044666 | MLL3/4 complex(GO:0044666) |
| 0.1 | 0.4 | GO:0030906 | retromer, cargo-selective complex(GO:0030906) |
| 0.1 | 1.7 | GO:0005847 | mRNA cleavage and polyadenylation specificity factor complex(GO:0005847) |
| 0.1 | 1.2 | GO:0008290 | F-actin capping protein complex(GO:0008290) |
| 0.1 | 0.4 | GO:0070436 | Grb2-EGFR complex(GO:0070436) |
| 0.1 | 1.6 | GO:0030904 | retromer complex(GO:0030904) |
| 0.1 | 0.2 | GO:0071159 | NF-kappaB complex(GO:0071159) |
| 0.1 | 0.7 | GO:0044233 | ER-mitochondrion membrane contact site(GO:0044233) |
| 0.1 | 0.6 | GO:1990023 | mitotic spindle midzone(GO:1990023) |
| 0.0 | 1.9 | GO:0005697 | telomerase holoenzyme complex(GO:0005697) |
| 0.0 | 1.1 | GO:0005861 | troponin complex(GO:0005861) |
| 0.0 | 1.3 | GO:0071004 | U2-type prespliceosome(GO:0071004) |
| 0.0 | 4.8 | GO:0005876 | spindle microtubule(GO:0005876) |
| 0.0 | 0.5 | GO:0033256 | I-kappaB/NF-kappaB complex(GO:0033256) |
| 0.0 | 5.0 | GO:0035577 | azurophil granule membrane(GO:0035577) |
| 0.0 | 3.2 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
| 0.0 | 1.2 | GO:0070971 | endoplasmic reticulum exit site(GO:0070971) |
| 0.0 | 0.4 | GO:0032541 | cortical endoplasmic reticulum(GO:0032541) |
| 0.0 | 0.6 | GO:0005677 | chromatin silencing complex(GO:0005677) |
| 0.0 | 1.6 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
| 0.0 | 4.1 | GO:0005637 | nuclear inner membrane(GO:0005637) |
| 0.0 | 0.6 | GO:0016600 | flotillin complex(GO:0016600) |
| 0.0 | 1.0 | GO:0005666 | DNA-directed RNA polymerase III complex(GO:0005666) |
| 0.0 | 0.2 | GO:0032449 | CBM complex(GO:0032449) |
| 0.0 | 2.4 | GO:0016235 | aggresome(GO:0016235) |
| 0.0 | 0.4 | GO:0000788 | nuclear nucleosome(GO:0000788) |
| 0.0 | 1.2 | GO:0044295 | axonal growth cone(GO:0044295) |
| 0.0 | 5.4 | GO:0005882 | intermediate filament(GO:0005882) |
| 0.0 | 0.9 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
| 0.0 | 0.9 | GO:0016580 | Sin3 complex(GO:0016580) |
| 0.0 | 0.7 | GO:0005852 | eukaryotic translation initiation factor 3 complex(GO:0005852) |
| 0.0 | 5.6 | GO:0005795 | Golgi stack(GO:0005795) |
| 0.0 | 0.8 | GO:0031307 | integral component of mitochondrial outer membrane(GO:0031307) |
| 0.0 | 0.5 | GO:0005689 | U12-type spliceosomal complex(GO:0005689) |
| 0.0 | 0.3 | GO:0005915 | zonula adherens(GO:0005915) |
| 0.0 | 2.0 | GO:0030315 | T-tubule(GO:0030315) |
| 0.0 | 0.6 | GO:0009925 | basal plasma membrane(GO:0009925) |
| 0.0 | 0.8 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
| 0.0 | 2.3 | GO:0005905 | clathrin-coated pit(GO:0005905) |
| 0.0 | 0.4 | GO:0033176 | proton-transporting V-type ATPase complex(GO:0033176) |
| 0.0 | 0.8 | GO:0000786 | nucleosome(GO:0000786) |
| 0.0 | 5.8 | GO:0005770 | late endosome(GO:0005770) |
| 0.0 | 0.3 | GO:0097610 | cell division site(GO:0032153) cleavage furrow(GO:0032154) cell division site part(GO:0032155) cell surface furrow(GO:0097610) |
| 0.0 | 0.3 | GO:0060077 | inhibitory synapse(GO:0060077) |
| 0.0 | 1.8 | GO:0030864 | cortical actin cytoskeleton(GO:0030864) |
| 0.0 | 0.3 | GO:0002199 | zona pellucida receptor complex(GO:0002199) |
| 0.0 | 3.3 | GO:0005681 | spliceosomal complex(GO:0005681) |
| 0.0 | 1.2 | GO:0030175 | filopodium(GO:0030175) |
| 0.0 | 0.4 | GO:0032839 | dendrite cytoplasm(GO:0032839) |
| 0.0 | 0.2 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
| 0.0 | 0.5 | GO:0030863 | cortical cytoskeleton(GO:0030863) |
| 0.0 | 0.5 | GO:0030687 | preribosome, large subunit precursor(GO:0030687) |
| 0.0 | 0.5 | GO:0030669 | clathrin-coated endocytic vesicle membrane(GO:0030669) |
| 0.0 | 4.7 | GO:0098857 | membrane raft(GO:0045121) membrane microdomain(GO:0098857) |
| 0.0 | 0.3 | GO:0005665 | DNA-directed RNA polymerase II, core complex(GO:0005665) |
| 0.0 | 3.3 | GO:0009897 | external side of plasma membrane(GO:0009897) |
| 0.0 | 1.6 | GO:0001725 | stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.1 | 6.3 | GO:0005150 | interleukin-1, Type I receptor binding(GO:0005150) |
| 1.8 | 21.7 | GO:0005094 | Rho GDP-dissociation inhibitor activity(GO:0005094) |
| 0.8 | 6.6 | GO:0016314 | phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314) |
| 0.7 | 1.4 | GO:0097110 | scaffold protein binding(GO:0097110) |
| 0.6 | 6.2 | GO:0004111 | creatine kinase activity(GO:0004111) |
| 0.6 | 5.6 | GO:0008449 | N-acetylglucosamine-6-sulfatase activity(GO:0008449) |
| 0.5 | 3.1 | GO:0016672 | oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610) |
| 0.5 | 1.9 | GO:0008336 | gamma-butyrobetaine dioxygenase activity(GO:0008336) |
| 0.4 | 1.7 | GO:0004917 | interleukin-7 receptor activity(GO:0004917) |
| 0.4 | 1.7 | GO:0052810 | 1-phosphatidylinositol-5-kinase activity(GO:0052810) |
| 0.4 | 5.0 | GO:0015379 | potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820) |
| 0.4 | 1.5 | GO:0032184 | SUMO polymer binding(GO:0032184) |
| 0.3 | 1.3 | GO:0052590 | sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591) |
| 0.3 | 7.0 | GO:0004861 | cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861) |
| 0.3 | 4.5 | GO:0016174 | NAD(P)H oxidase activity(GO:0016174) |
| 0.3 | 2.0 | GO:0042030 | ATPase inhibitor activity(GO:0042030) |
| 0.3 | 0.8 | GO:0008177 | succinate dehydrogenase (ubiquinone) activity(GO:0008177) 3 iron, 4 sulfur cluster binding(GO:0051538) |
| 0.3 | 3.9 | GO:0033192 | calmodulin-dependent protein phosphatase activity(GO:0033192) |
| 0.3 | 1.7 | GO:0039552 | RIG-I binding(GO:0039552) |
| 0.3 | 0.8 | GO:0061599 | molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599) |
| 0.3 | 5.1 | GO:0004716 | receptor signaling protein tyrosine kinase activity(GO:0004716) |
| 0.3 | 0.8 | GO:0016812 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812) |
| 0.2 | 4.5 | GO:0008494 | translation activator activity(GO:0008494) |
| 0.2 | 2.8 | GO:0004652 | polynucleotide adenylyltransferase activity(GO:0004652) |
| 0.2 | 2.6 | GO:0004705 | JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909) |
| 0.2 | 6.4 | GO:0005068 | transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068) |
| 0.2 | 1.9 | GO:0001875 | lipopolysaccharide receptor activity(GO:0001875) |
| 0.2 | 9.7 | GO:0005164 | tumor necrosis factor receptor binding(GO:0005164) |
| 0.2 | 4.2 | GO:0045499 | chemorepellent activity(GO:0045499) |
| 0.2 | 6.5 | GO:0017166 | vinculin binding(GO:0017166) |
| 0.2 | 0.5 | GO:0030626 | U12 snRNA binding(GO:0030626) |
| 0.2 | 1.2 | GO:0001042 | RNA polymerase I core binding(GO:0001042) |
| 0.2 | 0.5 | GO:0004464 | leukotriene-C4 synthase activity(GO:0004464) |
| 0.1 | 1.2 | GO:0004563 | beta-N-acetylhexosaminidase activity(GO:0004563) |
| 0.1 | 3.5 | GO:0097602 | cullin family protein binding(GO:0097602) |
| 0.1 | 1.8 | GO:0008526 | phosphatidylinositol transporter activity(GO:0008526) |
| 0.1 | 3.1 | GO:0016918 | retinal binding(GO:0016918) retinol binding(GO:0019841) |
| 0.1 | 8.7 | GO:0004693 | cyclin-dependent protein serine/threonine kinase activity(GO:0004693) |
| 0.1 | 1.7 | GO:0045159 | myosin II binding(GO:0045159) |
| 0.1 | 1.1 | GO:0051378 | amine binding(GO:0043176) serotonin binding(GO:0051378) |
| 0.1 | 0.7 | GO:0005499 | vitamin D binding(GO:0005499) |
| 0.1 | 1.1 | GO:0010859 | calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859) |
| 0.1 | 1.5 | GO:0032036 | myosin heavy chain binding(GO:0032036) |
| 0.1 | 4.1 | GO:0005521 | lamin binding(GO:0005521) |
| 0.1 | 4.5 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
| 0.1 | 0.6 | GO:0030144 | alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144) |
| 0.1 | 2.2 | GO:0031432 | titin binding(GO:0031432) |
| 0.1 | 4.0 | GO:0031683 | G-protein beta/gamma-subunit complex binding(GO:0031683) |
| 0.1 | 1.6 | GO:0042975 | peroxisome proliferator activated receptor binding(GO:0042975) |
| 0.1 | 1.1 | GO:0031014 | troponin T binding(GO:0031014) |
| 0.1 | 1.2 | GO:0001135 | transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135) |
| 0.1 | 6.2 | GO:0018024 | histone-lysine N-methyltransferase activity(GO:0018024) |
| 0.1 | 1.5 | GO:0008179 | adenylate cyclase binding(GO:0008179) |
| 0.1 | 1.0 | GO:0001056 | RNA polymerase III activity(GO:0001056) |
| 0.1 | 1.5 | GO:0005537 | mannose binding(GO:0005537) |
| 0.1 | 0.6 | GO:0035800 | deubiquitinase activator activity(GO:0035800) |
| 0.1 | 2.4 | GO:0000993 | RNA polymerase II core binding(GO:0000993) |
| 0.1 | 0.4 | GO:0022897 | peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897) |
| 0.1 | 0.7 | GO:0008097 | 5S rRNA binding(GO:0008097) |
| 0.1 | 0.3 | GO:0005105 | type 1 fibroblast growth factor receptor binding(GO:0005105) |
| 0.1 | 3.4 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
| 0.1 | 1.7 | GO:0008239 | dipeptidyl-peptidase activity(GO:0008239) |
| 0.1 | 0.7 | GO:0019869 | chloride channel inhibitor activity(GO:0019869) |
| 0.1 | 2.4 | GO:0051059 | NF-kappaB binding(GO:0051059) |
| 0.1 | 3.6 | GO:0036002 | pre-mRNA binding(GO:0036002) |
| 0.1 | 1.2 | GO:0001055 | RNA polymerase II activity(GO:0001055) |
| 0.1 | 0.7 | GO:0003831 | beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831) |
| 0.0 | 1.8 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
| 0.0 | 0.6 | GO:0015386 | potassium:proton antiporter activity(GO:0015386) |
| 0.0 | 0.3 | GO:0004609 | phosphatidylserine decarboxylase activity(GO:0004609) |
| 0.0 | 0.4 | GO:0019798 | procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798) |
| 0.0 | 1.9 | GO:0051721 | protein phosphatase 2A binding(GO:0051721) |
| 0.0 | 0.3 | GO:0051525 | NFAT protein binding(GO:0051525) |
| 0.0 | 2.2 | GO:0015026 | coreceptor activity(GO:0015026) |
| 0.0 | 0.6 | GO:0042809 | vitamin D receptor binding(GO:0042809) |
| 0.0 | 0.8 | GO:0043522 | leucine zipper domain binding(GO:0043522) |
| 0.0 | 0.6 | GO:0015250 | water channel activity(GO:0015250) |
| 0.0 | 1.1 | GO:0005041 | low-density lipoprotein receptor activity(GO:0005041) |
| 0.0 | 0.8 | GO:0009931 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) |
| 0.0 | 4.8 | GO:0008013 | beta-catenin binding(GO:0008013) |
| 0.0 | 2.6 | GO:0004712 | protein serine/threonine/tyrosine kinase activity(GO:0004712) |
| 0.0 | 0.8 | GO:0003995 | acyl-CoA dehydrogenase activity(GO:0003995) |
| 0.0 | 1.3 | GO:0070064 | proline-rich region binding(GO:0070064) |
| 0.0 | 0.7 | GO:0034185 | apolipoprotein binding(GO:0034185) |
| 0.0 | 8.6 | GO:0019887 | protein kinase regulator activity(GO:0019887) |
| 0.0 | 1.0 | GO:0042288 | MHC class I protein binding(GO:0042288) |
| 0.0 | 0.8 | GO:0019789 | SUMO transferase activity(GO:0019789) |
| 0.0 | 0.2 | GO:0097100 | supercoiled DNA binding(GO:0097100) |
| 0.0 | 0.5 | GO:0001222 | transcription corepressor binding(GO:0001222) |
| 0.0 | 2.8 | GO:0003725 | double-stranded RNA binding(GO:0003725) |
| 0.0 | 4.9 | GO:0001085 | RNA polymerase II transcription factor binding(GO:0001085) |
| 0.0 | 0.2 | GO:0001665 | alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665) |
| 0.0 | 0.4 | GO:0030957 | Tat protein binding(GO:0030957) |
| 0.0 | 0.6 | GO:0032454 | histone demethylase activity (H3-K9 specific)(GO:0032454) |
| 0.0 | 1.2 | GO:0035035 | histone acetyltransferase binding(GO:0035035) |
| 0.0 | 0.8 | GO:0019198 | transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198) |
| 0.0 | 1.5 | GO:0008170 | N-methyltransferase activity(GO:0008170) |
| 0.0 | 1.6 | GO:0035064 | methylated histone binding(GO:0035064) |
| 0.0 | 0.3 | GO:0031681 | G-protein beta-subunit binding(GO:0031681) |
| 0.0 | 0.2 | GO:0005078 | MAP-kinase scaffold activity(GO:0005078) |
| 0.0 | 0.2 | GO:0031419 | cobalamin binding(GO:0031419) |
| 0.0 | 0.2 | GO:0015165 | pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165) |
| 0.0 | 0.2 | GO:0070915 | lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915) |
| 0.0 | 0.1 | GO:0004679 | AMP-activated protein kinase activity(GO:0004679) |
| 0.0 | 0.1 | GO:0001032 | RNA polymerase III type 3 promoter DNA binding(GO:0001032) |
| 0.0 | 0.8 | GO:0003755 | peptidyl-prolyl cis-trans isomerase activity(GO:0003755) |
| 0.0 | 0.2 | GO:0004579 | dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
| 0.0 | 0.1 | GO:0048018 | receptor agonist activity(GO:0048018) |
| 0.0 | 0.5 | GO:0043027 | cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) |
| 0.0 | 0.5 | GO:0005109 | frizzled binding(GO:0005109) |
| 0.0 | 0.3 | GO:0032452 | histone demethylase activity(GO:0032452) |
| 0.0 | 0.5 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
| 0.0 | 0.4 | GO:0016702 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 7.0 | SA REG CASCADE OF CYCLIN EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
| 0.2 | 9.4 | SA B CELL RECEPTOR COMPLEXES | Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases. |
| 0.2 | 4.1 | PID THROMBIN PAR4 PATHWAY | PAR4-mediated thrombin signaling events |
| 0.2 | 21.8 | PID RHOA REG PATHWAY | Regulation of RhoA activity |
| 0.1 | 8.7 | PID IL3 PATHWAY | IL3-mediated signaling events |
| 0.1 | 6.5 | PID IL12 STAT4 PATHWAY | IL12 signaling mediated by STAT4 |
| 0.1 | 2.1 | PID ANTHRAX PATHWAY | Cellular roles of Anthrax toxin |
| 0.1 | 2.9 | PID ARF6 DOWNSTREAM PATHWAY | Arf6 downstream pathway |
| 0.1 | 6.8 | PID ALPHA SYNUCLEIN PATHWAY | Alpha-synuclein signaling |
| 0.1 | 5.9 | PID FCER1 PATHWAY | Fc-epsilon receptor I signaling in mast cells |
| 0.1 | 6.5 | PID IL1 PATHWAY | IL1-mediated signaling events |
| 0.1 | 3.7 | PID ERBB2 ERBB3 PATHWAY | ErbB2/ErbB3 signaling events |
| 0.1 | 5.0 | PID NFAT TFPATHWAY | Calcineurin-regulated NFAT-dependent transcription in lymphocytes |
| 0.1 | 2.9 | PID IL8 CXCR2 PATHWAY | IL8- and CXCR2-mediated signaling events |
| 0.1 | 1.7 | PID AVB3 OPN PATHWAY | Osteopontin-mediated events |
| 0.0 | 2.8 | PID FAK PATHWAY | Signaling events mediated by focal adhesion kinase |
| 0.0 | 3.5 | PID TAP63 PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 0.0 | 5.0 | PID BETA CATENIN NUC PATHWAY | Regulation of nuclear beta catenin signaling and target gene transcription |
| 0.0 | 0.6 | PID NECTIN PATHWAY | Nectin adhesion pathway |
| 0.0 | 1.5 | PID TGFBR PATHWAY | TGF-beta receptor signaling |
| 0.0 | 0.8 | ST P38 MAPK PATHWAY | p38 MAPK Pathway |
| 0.0 | 2.6 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.0 | 6.3 | NABA SECRETED FACTORS | Genes encoding secreted soluble factors |
| 0.0 | 0.9 | PID ECADHERIN STABILIZATION PATHWAY | Stabilization and expansion of the E-cadherin adherens junction |
| 0.0 | 0.6 | PID IL6 7 PATHWAY | IL6-mediated signaling events |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 4.1 | REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE | Genes involved in Regulation of Insulin Secretion by Acetylcholine |
| 0.2 | 2.9 | REACTOME CD28 DEPENDENT VAV1 PATHWAY | Genes involved in CD28 dependent Vav1 pathway |
| 0.2 | 9.4 | REACTOME REGULATION OF SIGNALING BY CBL | Genes involved in Regulation of signaling by CBL |
| 0.2 | 8.7 | REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE | Genes involved in Sema4D induced cell migration and growth-cone collapse |
| 0.2 | 1.0 | REACTOME SEMA4D IN SEMAPHORIN SIGNALING | Genes involved in Sema4D in semaphorin signaling |
| 0.1 | 1.1 | REACTOME ERKS ARE INACTIVATED | Genes involved in ERKs are inactivated |
| 0.1 | 1.1 | REACTOME SEROTONIN RECEPTORS | Genes involved in Serotonin receptors |
| 0.1 | 4.2 | REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA | Genes involved in Circadian Repression of Expression by REV-ERBA |
| 0.1 | 3.5 | REACTOME FORMATION OF INCISION COMPLEX IN GG NER | Genes involved in Formation of incision complex in GG-NER |
| 0.1 | 2.8 | REACTOME PROCESSING OF INTRONLESS PRE MRNAS | Genes involved in Processing of Intronless Pre-mRNAs |
| 0.1 | 0.8 | REACTOME SPRY REGULATION OF FGF SIGNALING | Genes involved in Spry regulation of FGF signaling |
| 0.1 | 24.7 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
| 0.1 | 0.5 | REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES | Genes involved in Cross-presentation of soluble exogenous antigens (endosomes) |
| 0.1 | 1.7 | REACTOME IL 7 SIGNALING | Genes involved in Interleukin-7 signaling |
| 0.1 | 2.6 | REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS | Genes involved in Activation of the AP-1 family of transcription factors |
| 0.1 | 14.7 | REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS | Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements |
| 0.1 | 6.3 | REACTOME G1 PHASE | Genes involved in G1 Phase |
| 0.1 | 6.0 | REACTOME IL1 SIGNALING | Genes involved in Interleukin-1 signaling |
| 0.1 | 3.1 | REACTOME GLUTATHIONE CONJUGATION | Genes involved in Glutathione conjugation |
| 0.1 | 16.5 | REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES | Genes involved in Metabolism of amino acids and derivatives |
| 0.0 | 2.5 | REACTOME GENERATION OF SECOND MESSENGER MOLECULES | Genes involved in Generation of second messenger molecules |
| 0.0 | 0.6 | REACTOME PASSIVE TRANSPORT BY AQUAPORINS | Genes involved in Passive Transport by Aquaporins |
| 0.0 | 0.8 | REACTOME THE NLRP3 INFLAMMASOME | Genes involved in The NLRP3 inflammasome |
| 0.0 | 1.0 | REACTOME RNA POL III CHAIN ELONGATION | Genes involved in RNA Polymerase III Chain Elongation |
| 0.0 | 0.8 | REACTOME CITRIC ACID CYCLE TCA CYCLE | Genes involved in Citric acid cycle (TCA cycle) |
| 0.0 | 1.5 | REACTOME SIGNALING BY ROBO RECEPTOR | Genes involved in Signaling by Robo receptor |
| 0.0 | 0.9 | REACTOME G0 AND EARLY G1 | Genes involved in G0 and Early G1 |
| 0.0 | 1.4 | REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS | Genes involved in Caspase-mediated cleavage of cytoskeletal proteins |
| 0.0 | 0.7 | REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC | Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC |
| 0.0 | 0.4 | REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS | Genes involved in Elevation of cytosolic Ca2+ levels |
| 0.0 | 1.2 | REACTOME LYSOSOME VESICLE BIOGENESIS | Genes involved in Lysosome Vesicle Biogenesis |
| 0.0 | 0.7 | REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS | Genes involved in Proteolytic cleavage of SNARE complex proteins |
| 0.0 | 1.9 | REACTOME MYD88 MAL CASCADE INITIATED ON PLASMA MEMBRANE | Genes involved in MyD88:Mal cascade initiated on plasma membrane |
| 0.0 | 0.5 | REACTOME PERK REGULATED GENE EXPRESSION | Genes involved in PERK regulated gene expression |
| 0.0 | 0.5 | REACTOME ER PHAGOSOME PATHWAY | Genes involved in ER-Phagosome pathway |
| 0.0 | 1.8 | REACTOME O LINKED GLYCOSYLATION OF MUCINS | Genes involved in O-linked glycosylation of mucins |
| 0.0 | 0.6 | REACTOME N GLYCAN ANTENNAE ELONGATION | Genes involved in N-Glycan antennae elongation |
| 0.0 | 1.0 | REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS | Genes involved in Apoptotic cleavage of cellular proteins |
| 0.0 | 2.2 | REACTOME MEIOTIC SYNAPSIS | Genes involved in Meiotic Synapsis |
| 0.0 | 0.8 | REACTOME SIGNALING BY HIPPO | Genes involved in Signaling by Hippo |
| 0.0 | 0.5 | REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA | Genes involved in G beta:gamma signalling through PLC beta |
| 0.0 | 0.7 | REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT | Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT) |
| 0.0 | 0.9 | REACTOME ADHERENS JUNCTIONS INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.0 | 0.3 | REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
| 0.0 | 0.4 | REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 | Genes involved in Regulation of AMPK activity via LKB1 |
| 0.0 | 0.2 | REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION | Genes involved in Mitochondrial Fatty Acid Beta-Oxidation |