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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for SPIC

Z-value: 0.33

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Transcription factors associated with SPIC

Gene Symbol Gene ID Gene Info
SPIC
ENSG00000166211.6 Spi-C transcription factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SPIChg19_v2_chr12_+_101869096_101869199-0.145.7e-01Click!

Activity profile of SPIC motif

Sorted Z-values of SPIC motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_8693469 1.09 ENST00000545274.1
ENST00000446457.2
CLEC4E
C-type lectin domain family 4, member E
chr12_-_8693539 0.84 ENST00000299663.3
CLEC4E
C-type lectin domain family 4, member E
chr14_-_23285069 0.80 ENST00000554758.1
ENST00000397528.4
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr14_-_23285011 0.68 ENST00000397532.3
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr11_-_102401469 0.65 ENST00000260227.4
MMP7
matrix metallopeptidase 7 (matrilysin, uterine)
chr14_-_23284703 0.57 ENST00000555911.1
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr2_+_120187465 0.53 ENST00000409826.1
ENST00000417645.1
TMEM37
transmembrane protein 37
chr17_-_79633590 0.50 ENST00000374741.3
ENST00000571503.1
OXLD1
oxidoreductase-like domain containing 1
chr19_+_859654 0.50 ENST00000592860.1
CFD
complement factor D (adipsin)
chr21_-_43786634 0.45 ENST00000291527.2
TFF1
trefoil factor 1
chr12_+_47610315 0.44 ENST00000548348.1
ENST00000549500.1
PCED1B
PC-esterase domain containing 1B
chrY_+_2709527 0.44 ENST00000250784.8
RPS4Y1
ribosomal protein S4, Y-linked 1
chr5_+_175299743 0.39 ENST00000502265.1
CPLX2
complexin 2
chr12_+_105724613 0.38 ENST00000549934.2
C12orf75
chromosome 12 open reading frame 75
chr19_-_36233332 0.37 ENST00000592537.1
ENST00000246532.1
ENST00000344990.3
ENST00000588992.1
IGFLR1
IGF-like family receptor 1
chr1_-_153518270 0.37 ENST00000354332.4
ENST00000368716.4
S100A4
S100 calcium binding protein A4
chr19_+_45417504 0.37 ENST00000588750.1
ENST00000588802.1
APOC1
apolipoprotein C-I
chr19_+_859425 0.37 ENST00000327726.6
CFD
complement factor D (adipsin)
chr19_+_14551066 0.37 ENST00000342216.4
PKN1
protein kinase N1
chr16_+_29465822 0.37 ENST00000330181.5
ENST00000351581.4
SLX1B
SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae)
chr16_+_30205225 0.36 ENST00000345535.4
ENST00000251303.6
SLX1A
SLX1 structure-specific endonuclease subunit homolog A (S. cerevisiae)
chr19_-_18391708 0.35 ENST00000600972.1
JUND
jun D proto-oncogene
chr4_-_89152474 0.34 ENST00000515655.1
ABCG2
ATP-binding cassette, sub-family G (WHITE), member 2
chr16_-_88717482 0.34 ENST00000261623.3
CYBA
cytochrome b-245, alpha polypeptide
chr12_+_104697504 0.34 ENST00000527879.1
EID3
EP300 interacting inhibitor of differentiation 3
chr22_-_36013368 0.34 ENST00000442617.1
ENST00000397326.2
ENST00000397328.1
ENST00000451685.1
MB
myoglobin
chr12_+_105724414 0.34 ENST00000443585.1
ENST00000552457.1
ENST00000549893.1
C12orf75
chromosome 12 open reading frame 75
chr3_+_52321827 0.32 ENST00000473032.1
ENST00000305690.8
ENST00000354773.4
ENST00000471180.1
ENST00000436784.2
GLYCTK
glycerate kinase
chr19_+_13261216 0.32 ENST00000587885.1
ENST00000292433.3
IER2
immediate early response 2
chr17_-_15168624 0.32 ENST00000312280.3
ENST00000494511.1
ENST00000580584.1
PMP22
peripheral myelin protein 22
chr20_-_2451395 0.31 ENST00000339610.6
ENST00000381342.2
ENST00000438552.2
SNRPB
small nuclear ribonucleoprotein polypeptides B and B1
chr11_-_64885111 0.31 ENST00000528598.1
ENST00000310597.4
ZNHIT2
zinc finger, HIT-type containing 2
chr20_-_2821756 0.31 ENST00000356872.3
ENST00000439542.1
PCED1A
PC-esterase domain containing 1A
chr12_+_53693466 0.31 ENST00000267103.5
ENST00000548632.1
C12orf10
chromosome 12 open reading frame 10
chr19_-_12780211 0.30 ENST00000597961.1
ENST00000598732.1
ENST00000222190.5
CTD-2192J16.24
WDR83OS
Uncharacterized protein
WD repeat domain 83 opposite strand
chr19_-_41903161 0.30 ENST00000602129.1
ENST00000593771.1
ENST00000596905.1
ENST00000221233.4
EXOSC5
exosome component 5
chr15_-_26874230 0.30 ENST00000400188.3
GABRB3
gamma-aminobutyric acid (GABA) A receptor, beta 3
chr10_-_99161033 0.29 ENST00000315563.6
ENST00000370992.4
ENST00000414986.1
RRP12
ribosomal RNA processing 12 homolog (S. cerevisiae)
chr1_-_150738261 0.29 ENST00000448301.2
ENST00000368985.3
CTSS
cathepsin S
chr1_+_196788887 0.29 ENST00000320493.5
ENST00000367424.4
ENST00000367421.3
CFHR1
CFHR2
complement factor H-related 1
complement factor H-related 2
chr4_-_88312301 0.29 ENST00000507286.1
HSD17B11
hydroxysteroid (17-beta) dehydrogenase 11
chr17_+_72427477 0.29 ENST00000342648.5
ENST00000481232.1
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr14_+_32414059 0.28 ENST00000553330.1
RP11-187E13.1
Uncharacterized protein
chr3_+_28283069 0.28 ENST00000466830.1
ENST00000423894.1
CMC1
C-x(9)-C motif containing 1
chrX_+_55478538 0.28 ENST00000342972.1
MAGEH1
melanoma antigen family H, 1
chr5_-_78281623 0.28 ENST00000521117.1
ARSB
arylsulfatase B
chr10_+_112257596 0.28 ENST00000369583.3
DUSP5
dual specificity phosphatase 5
chr5_+_174151536 0.28 ENST00000239243.6
ENST00000507785.1
MSX2
msh homeobox 2
chr20_-_2821271 0.27 ENST00000448755.1
ENST00000360652.2
PCED1A
PC-esterase domain containing 1A
chr1_+_156698708 0.27 ENST00000519086.1
RRNAD1
ribosomal RNA adenine dimethylase domain containing 1
chr20_-_4795747 0.27 ENST00000379376.2
RASSF2
Ras association (RalGDS/AF-6) domain family member 2
chr1_-_246729544 0.27 ENST00000544618.1
ENST00000366514.4
TFB2M
transcription factor B2, mitochondrial
chr19_+_50919056 0.27 ENST00000599632.1
CTD-2545M3.6
CTD-2545M3.6
chr2_+_217363559 0.27 ENST00000600880.1
ENST00000446558.1
RPL37A
ribosomal protein L37a
chr19_+_49838653 0.26 ENST00000598095.1
ENST00000426897.2
ENST00000323906.4
ENST00000535669.2
ENST00000597602.1
ENST00000595660.1
CD37
CD37 molecule
chr7_+_139025875 0.26 ENST00000297534.6
C7orf55
chromosome 7 open reading frame 55
chr17_-_79269067 0.26 ENST00000288439.5
ENST00000374759.3
SLC38A10
solute carrier family 38, member 10
chrY_+_15016725 0.26 ENST00000336079.3
DDX3Y
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
chr11_+_22646739 0.25 ENST00000428556.2
AC103801.2
AC103801.2
chr19_-_46272462 0.25 ENST00000317578.6
SIX5
SIX homeobox 5
chr11_-_67120974 0.25 ENST00000539074.1
ENST00000312419.3
POLD4
polymerase (DNA-directed), delta 4, accessory subunit
chr11_+_2421718 0.25 ENST00000380996.5
ENST00000333256.6
ENST00000380992.1
ENST00000437110.1
ENST00000435795.1
TSSC4
tumor suppressing subtransferable candidate 4
chr10_+_26727333 0.25 ENST00000356785.4
APBB1IP
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr6_+_126240442 0.25 ENST00000448104.1
ENST00000438495.1
ENST00000444128.1
NCOA7
nuclear receptor coactivator 7
chrX_+_47092314 0.24 ENST00000218348.3
USP11
ubiquitin specific peptidase 11
chr3_-_142720267 0.24 ENST00000597953.1
RP11-91G21.1
RP11-91G21.1
chr10_+_72238517 0.24 ENST00000263563.6
PALD1
phosphatase domain containing, paladin 1
chr1_+_156698234 0.24 ENST00000368218.4
ENST00000368216.4
RRNAD1
ribosomal RNA adenine dimethylase domain containing 1
chr11_+_123430948 0.23 ENST00000529432.1
ENST00000534764.1
GRAMD1B
GRAM domain containing 1B
chr11_-_64851496 0.23 ENST00000404147.3
ENST00000275517.3
CDCA5
cell division cycle associated 5
chrY_+_15016013 0.23 ENST00000360160.4
ENST00000454054.1
DDX3Y
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
chr1_+_22351977 0.23 ENST00000420503.1
ENST00000416769.1
ENST00000404210.2
LINC00339
long intergenic non-protein coding RNA 339
chr17_+_67498538 0.23 ENST00000589647.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr19_+_12780512 0.23 ENST00000242796.4
WDR83
WD repeat domain 83
chr11_-_615570 0.22 ENST00000525445.1
ENST00000348655.6
ENST00000397566.1
IRF7
interferon regulatory factor 7
chr11_-_615942 0.22 ENST00000397562.3
ENST00000330243.5
ENST00000397570.1
ENST00000397574.2
IRF7
interferon regulatory factor 7
chr16_-_31085514 0.22 ENST00000300849.4
ZNF668
zinc finger protein 668
chr1_+_156698743 0.22 ENST00000524343.1
RRNAD1
ribosomal RNA adenine dimethylase domain containing 1
chr17_+_72426891 0.22 ENST00000392627.1
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr11_-_68671264 0.21 ENST00000362034.2
MRPL21
mitochondrial ribosomal protein L21
chr17_+_9745786 0.21 ENST00000304773.5
GLP2R
glucagon-like peptide 2 receptor
chr19_+_17413663 0.21 ENST00000594999.1
MRPL34
mitochondrial ribosomal protein L34
chr15_-_74284613 0.21 ENST00000316911.6
ENST00000564777.1
ENST00000566081.1
ENST00000316900.5
STOML1
stomatin (EPB72)-like 1
chr19_+_58898627 0.21 ENST00000598098.1
ENST00000598495.1
ENST00000196551.3
ENST00000596046.1
RPS5
ribosomal protein S5
chr8_-_95229531 0.21 ENST00000450165.2
CDH17
cadherin 17, LI cadherin (liver-intestine)
chr17_+_7487146 0.21 ENST00000396501.4
ENST00000584378.1
ENST00000423172.2
ENST00000579445.1
ENST00000585217.1
ENST00000581380.1
MPDU1
mannose-P-dolichol utilization defect 1
chr1_+_174968564 0.20 ENST00000426793.1
CACYBP
calcyclin binding protein
chr19_+_41082755 0.20 ENST00000291842.5
ENST00000600733.1
SHKBP1
SH3KBP1 binding protein 1
chr17_+_21730180 0.20 ENST00000584398.1
UBBP4
ubiquitin B pseudogene 4
chr5_-_140013275 0.20 ENST00000512545.1
ENST00000302014.6
ENST00000401743.2
CD14
CD14 molecule
chr10_-_72141330 0.20 ENST00000395011.1
ENST00000395010.1
LRRC20
leucine rich repeat containing 20
chr7_-_32529973 0.20 ENST00000410044.1
ENST00000409987.1
ENST00000409782.1
ENST00000450169.2
LSM5
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr6_+_12290586 0.20 ENST00000379375.5
EDN1
endothelin 1
chr19_-_51875894 0.20 ENST00000600427.1
ENST00000595217.1
ENST00000221978.5
NKG7
natural killer cell group 7 sequence
chr12_+_48577366 0.20 ENST00000316554.3
C12orf68
chromosome 12 open reading frame 68
chr2_-_25451065 0.20 ENST00000606328.1
RP11-458N5.1
RP11-458N5.1
chr11_+_61560348 0.20 ENST00000535723.1
ENST00000574708.1
FEN1
FADS2
flap structure-specific endonuclease 1
fatty acid desaturase 2
chr2_-_3381561 0.19 ENST00000443925.2
ENST00000441271.1
ENST00000444776.1
ENST00000398659.4
ENST00000382125.4
TSSC1
tumor suppressing subtransferable candidate 1
chr6_+_49431073 0.19 ENST00000335783.3
CENPQ
centromere protein Q
chr19_-_55919087 0.19 ENST00000587845.1
ENST00000589978.1
ENST00000264552.9
UBE2S
ubiquitin-conjugating enzyme E2S
chr19_+_45542295 0.19 ENST00000221455.3
ENST00000391953.4
ENST00000588936.1
CLASRP
CLK4-associating serine/arginine rich protein
chr4_+_84457529 0.19 ENST00000264409.4
AGPAT9
1-acylglycerol-3-phosphate O-acyltransferase 9
chr1_+_203830703 0.19 ENST00000414487.2
SNRPE
small nuclear ribonucleoprotein polypeptide E
chr1_-_36863481 0.19 ENST00000315732.2
LSM10
LSM10, U7 small nuclear RNA associated
chr11_+_72983246 0.19 ENST00000393590.2
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr2_-_152382500 0.19 ENST00000434685.1
NEB
nebulin
chr4_+_84457250 0.19 ENST00000395226.2
AGPAT9
1-acylglycerol-3-phosphate O-acyltransferase 9
chr7_-_99698338 0.18 ENST00000354230.3
ENST00000425308.1
MCM7
minichromosome maintenance complex component 7
chr19_-_8642289 0.18 ENST00000596675.1
ENST00000338257.8
MYO1F
myosin IF
chr11_-_75236867 0.18 ENST00000376282.3
ENST00000336898.3
GDPD5
glycerophosphodiester phosphodiesterase domain containing 5
chr1_-_32210275 0.18 ENST00000440175.2
BAI2
brain-specific angiogenesis inhibitor 2
chr5_-_78281603 0.18 ENST00000264914.4
ARSB
arylsulfatase B
chr19_+_41082802 0.18 ENST00000600718.1
SHKBP1
SH3KBP1 binding protein 1
chr4_+_74606223 0.18 ENST00000307407.3
ENST00000401931.1
IL8
interleukin 8
chr15_-_80263506 0.18 ENST00000335661.6
BCL2A1
BCL2-related protein A1
chr16_+_31271274 0.18 ENST00000287497.8
ENST00000544665.3
ITGAM
integrin, alpha M (complement component 3 receptor 3 subunit)
chr1_-_204183071 0.18 ENST00000308302.3
GOLT1A
golgi transport 1A
chr19_+_6772710 0.18 ENST00000304076.2
ENST00000602142.1
ENST00000596764.1
VAV1
vav 1 guanine nucleotide exchange factor
chr15_-_65282274 0.18 ENST00000204566.2
SPG21
spastic paraplegia 21 (autosomal recessive, Mast syndrome)
chr17_+_18601299 0.18 ENST00000572555.1
ENST00000395902.3
ENST00000449552.2
TRIM16L
tripartite motif containing 16-like
chr19_-_9968816 0.18 ENST00000590841.1
OLFM2
olfactomedin 2
chr18_+_2846972 0.18 ENST00000254528.3
EMILIN2
elastin microfibril interfacer 2
chr2_+_113342163 0.17 ENST00000409719.1
CHCHD5
coiled-coil-helix-coiled-coil-helix domain containing 5
chr15_-_74284558 0.17 ENST00000359750.4
ENST00000541638.1
ENST00000562453.1
STOML1
stomatin (EPB72)-like 1
chr2_+_25015968 0.17 ENST00000380834.2
ENST00000473706.1
CENPO
centromere protein O
chrX_-_100604184 0.17 ENST00000372902.3
TIMM8A
translocase of inner mitochondrial membrane 8 homolog A (yeast)
chr10_+_104614008 0.17 ENST00000369883.3
C10orf32
chromosome 10 open reading frame 32
chr3_-_149095652 0.17 ENST00000305366.3
TM4SF1
transmembrane 4 L six family member 1
chr16_+_699319 0.17 ENST00000549091.1
ENST00000293879.4
WDR90
WD repeat domain 90
chr17_-_37844267 0.17 ENST00000579146.1
ENST00000378011.4
ENST00000429199.2
ENST00000300658.4
PGAP3
post-GPI attachment to proteins 3
chr17_-_46690839 0.17 ENST00000498634.2
HOXB8
homeobox B8
chr12_-_121019165 0.17 ENST00000341039.2
ENST00000357500.4
POP5
processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae)
chr11_-_57283159 0.17 ENST00000533263.1
ENST00000278426.3
SLC43A1
solute carrier family 43 (amino acid system L transporter), member 1
chr11_+_47430133 0.17 ENST00000531974.1
ENST00000531419.1
ENST00000531865.1
ENST00000362021.4
ENST00000354884.4
SLC39A13
solute carrier family 39 (zinc transporter), member 13
chr19_+_56186557 0.17 ENST00000270460.6
EPN1
epsin 1
chr7_+_100450328 0.17 ENST00000540482.1
ENST00000418037.1
ENST00000428758.1
ENST00000275729.3
ENST00000415287.1
ENST00000354161.3
ENST00000416675.1
SLC12A9
solute carrier family 12, member 9
chr2_+_175352114 0.17 ENST00000444196.1
ENST00000417038.1
ENST00000606406.1
AC010894.3
AC010894.3
chr17_+_34958001 0.17 ENST00000250156.7
MRM1
mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
chr16_+_11439286 0.17 ENST00000312499.5
ENST00000576027.1
RMI2
RecQ mediated genome instability 2
chr17_+_48450575 0.16 ENST00000338165.4
ENST00000393271.2
ENST00000511519.2
EME1
essential meiotic structure-specific endonuclease 1
chr12_+_54447637 0.16 ENST00000609810.1
ENST00000430889.2
HOXC4
HOXC4
homeobox C4
Homeobox protein Hox-C4
chr3_+_148847371 0.16 ENST00000296051.2
ENST00000460120.1
HPS3
Hermansky-Pudlak syndrome 3
chr8_+_32579271 0.16 ENST00000518084.1
NRG1
neuregulin 1
chr10_-_121302195 0.16 ENST00000369103.2
RGS10
regulator of G-protein signaling 10
chr17_+_37356528 0.16 ENST00000225430.4
RPL19
ribosomal protein L19
chr11_-_60010556 0.16 ENST00000427611.2
MS4A4E
membrane-spanning 4-domains, subfamily A, member 4E
chr11_-_66313699 0.16 ENST00000526986.1
ENST00000310442.3
ZDHHC24
zinc finger, DHHC-type containing 24
chr11_+_65408273 0.16 ENST00000394227.3
SIPA1
signal-induced proliferation-associated 1
chr19_+_45542773 0.16 ENST00000544944.2
CLASRP
CLK4-associating serine/arginine rich protein
chr6_-_125623046 0.16 ENST00000608295.1
ENST00000398153.2
ENST00000608284.1
ENST00000368377.4
HDDC2
HD domain containing 2
chr22_-_39928823 0.16 ENST00000334678.3
RPS19BP1
ribosomal protein S19 binding protein 1
chr16_+_30078811 0.16 ENST00000564688.1
ALDOA
aldolase A, fructose-bisphosphate
chr2_+_219724544 0.16 ENST00000233948.3
WNT6
wingless-type MMTV integration site family, member 6
chr16_-_88717423 0.16 ENST00000568278.1
ENST00000569359.1
ENST00000567174.1
CYBA
cytochrome b-245, alpha polypeptide
chr12_-_81331460 0.16 ENST00000549417.1
LIN7A
lin-7 homolog A (C. elegans)
chr12_+_132413798 0.16 ENST00000440818.2
ENST00000542167.2
ENST00000538037.1
ENST00000456665.2
PUS1
pseudouridylate synthase 1
chr8_-_80942467 0.15 ENST00000518271.1
ENST00000276585.4
ENST00000521605.1
MRPS28
mitochondrial ribosomal protein S28
chr15_+_62853562 0.15 ENST00000561311.1
TLN2
talin 2
chr2_-_25016251 0.15 ENST00000328379.5
PTRHD1
peptidyl-tRNA hydrolase domain containing 1
chr2_-_99224915 0.15 ENST00000328709.3
ENST00000409997.1
COA5
cytochrome c oxidase assembly factor 5
chr2_+_217363826 0.15 ENST00000441179.2
RPL37A
ribosomal protein L37a
chr17_-_72709050 0.15 ENST00000583937.1
ENST00000301573.9
ENST00000326165.6
ENST00000469092.1
CD300LF
CD300 molecule-like family member f
chrX_-_11129229 0.15 ENST00000608176.1
ENST00000433747.2
ENST00000608576.1
ENST00000608916.1
RP11-120D5.1
RP11-120D5.1
chr16_-_66968265 0.15 ENST00000567511.1
ENST00000422424.2
FAM96B
family with sequence similarity 96, member B
chr3_-_150264272 0.15 ENST00000491660.1
ENST00000487153.1
ENST00000239944.2
SERP1
stress-associated endoplasmic reticulum protein 1
chr12_-_53297432 0.15 ENST00000546900.1
KRT8
keratin 8
chr3_-_194030493 0.15 ENST00000456816.1
ENST00000414120.1
ENST00000429578.1
LINC00887
long intergenic non-protein coding RNA 887
chr18_-_33077868 0.15 ENST00000590757.1
ENST00000592173.1
ENST00000441607.2
ENST00000587450.1
ENST00000589258.1
INO80C
RP11-322E11.6
INO80 complex subunit C
Uncharacterized protein
chr16_+_70488480 0.15 ENST00000572784.1
ENST00000574784.1
ENST00000571514.1
ENST00000378912.2
ENST00000428974.2
ENST00000573352.1
ENST00000576453.1
FUK
fucokinase
chr11_+_62538775 0.15 ENST00000294168.3
ENST00000526261.1
TAF6L
TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
chr11_-_22647350 0.15 ENST00000327470.3
FANCF
Fanconi anemia, complementation group F
chr1_+_38273818 0.15 ENST00000373042.4
C1orf122
chromosome 1 open reading frame 122
chr12_+_132413739 0.15 ENST00000443358.2
PUS1
pseudouridylate synthase 1
chr16_+_89627061 0.15 ENST00000311528.5
ENST00000563270.1
ENST00000567815.1
ENST00000452368.3
ENST00000467736.1
ENST00000393099.3
RPL13
ribosomal protein L13
chr2_+_228189867 0.15 ENST00000423098.1
ENST00000304593.9
MFF
mitochondrial fission factor
chr12_-_6772303 0.15 ENST00000396807.4
ENST00000446105.2
ENST00000341550.4
ING4
inhibitor of growth family, member 4
chr2_+_25016282 0.15 ENST00000260662.1
CENPO
centromere protein O
chr21_+_34638656 0.14 ENST00000290200.2
IL10RB
interleukin 10 receptor, beta
chr15_-_90358048 0.14 ENST00000300060.6
ENST00000560137.1
ANPEP
alanyl (membrane) aminopeptidase
chr19_-_40596767 0.14 ENST00000599972.1
ENST00000450241.2
ENST00000595687.2
ZNF780A
zinc finger protein 780A
chr22_-_21984282 0.14 ENST00000398873.3
ENST00000292778.6
YDJC
YdjC homolog (bacterial)
chr5_-_443239 0.14 ENST00000408966.2
C5orf55
chromosome 5 open reading frame 55
chr1_+_212208919 0.14 ENST00000366991.4
ENST00000542077.1
DTL
denticleless E3 ubiquitin protein ligase homolog (Drosophila)
chr2_-_228582709 0.14 ENST00000541617.1
ENST00000409456.2
ENST00000409287.1
ENST00000258403.3
SLC19A3
solute carrier family 19 (thiamine transporter), member 3
chr19_-_55628700 0.14 ENST00000592993.1
PPP1R12C
protein phosphatase 1, regulatory subunit 12C
chr12_-_120907374 0.14 ENST00000550458.1
SRSF9
serine/arginine-rich splicing factor 9
chr11_-_68671244 0.14 ENST00000567045.1
ENST00000450904.2
MRPL21
mitochondrial ribosomal protein L21
chr11_+_7618413 0.14 ENST00000528883.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr17_+_62075703 0.14 ENST00000577953.1
ENST00000582540.1
ENST00000579184.1
ENST00000425164.3
ENST00000412177.1
ENST00000539996.1
ENST00000583891.1
ENST00000580752.1
C17orf72
chromosome 17 open reading frame 72
chr7_+_73106926 0.14 ENST00000453316.1
WBSCR22
Williams Beuren syndrome chromosome region 22
chr17_+_46048376 0.14 ENST00000338399.4
CDK5RAP3
CDK5 regulatory subunit associated protein 3
chr19_+_32896697 0.14 ENST00000586987.1
DPY19L3
dpy-19-like 3 (C. elegans)
chr14_+_96722539 0.14 ENST00000553356.1
BDKRB1
bradykinin receptor B1
chr17_+_46048497 0.14 ENST00000583352.1
CDK5RAP3
CDK5 regulatory subunit associated protein 3
chr17_-_4710288 0.14 ENST00000571067.1
RP11-81A22.5
RP11-81A22.5
chr1_+_44440575 0.14 ENST00000532642.1
ENST00000236067.4
ENST00000471859.2
ATP6V0B
ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
chr16_+_28875126 0.13 ENST00000359285.5
ENST00000538342.1
SH2B1
SH2B adaptor protein 1
chr20_+_2821366 0.13 ENST00000453689.1
ENST00000417508.1
VPS16
vacuolar protein sorting 16 homolog (S. cerevisiae)
chr19_+_32896646 0.13 ENST00000392250.2
DPY19L3
dpy-19-like 3 (C. elegans)
chr19_+_56186606 0.13 ENST00000085079.7
EPN1
epsin 1

Network of associatons between targets according to the STRING database.

First level regulatory network of SPIC

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.2 GO:1990822 basic amino acid transmembrane transport(GO:1990822)
0.2 0.6 GO:0061580 colon epithelial cell migration(GO:0061580)
0.1 0.4 GO:0070902 mitochondrial tRNA pseudouridine synthesis(GO:0070902)
0.1 0.5 GO:1904845 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.1 0.6 GO:0034124 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124)
0.1 0.4 GO:0010900 negative regulation of phosphatidylcholine catabolic process(GO:0010900)
0.1 0.3 GO:0051795 positive regulation of catagen(GO:0051795) activation of meiosis(GO:0090427)
0.1 0.2 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.1 0.1 GO:0017004 cytochrome complex assembly(GO:0017004)
0.1 0.3 GO:1902723 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.1 0.3 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.1 0.5 GO:0071727 toll-like receptor TLR1:TLR2 signaling pathway(GO:0038123) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.1 0.3 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.1 0.3 GO:0042144 vacuole fusion, non-autophagic(GO:0042144)
0.1 0.4 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.1 0.3 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.1 0.3 GO:0061624 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.1 0.3 GO:0007525 somatic muscle development(GO:0007525)
0.1 0.4 GO:1904431 positive regulation of t-circle formation(GO:1904431)
0.0 0.2 GO:0060584 nitric oxide transport(GO:0030185) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.0 0.3 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.2 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.0 0.2 GO:0046203 spermidine catabolic process(GO:0046203)
0.0 0.4 GO:0021840 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.0 0.2 GO:0072709 cellular response to sorbitol(GO:0072709)
0.0 0.1 GO:0006425 glutaminyl-tRNA aminoacylation(GO:0006425)
0.0 0.2 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.0 0.2 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.0 0.2 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.0 0.9 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.3 GO:0006710 androgen catabolic process(GO:0006710)
0.0 0.1 GO:0038163 endomitotic cell cycle(GO:0007113) thrombopoietin-mediated signaling pathway(GO:0038163)
0.0 0.2 GO:1900063 regulation of peroxisome organization(GO:1900063)
0.0 0.1 GO:0002232 leukocyte chemotaxis involved in inflammatory response(GO:0002232)
0.0 0.2 GO:0038108 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
0.0 0.0 GO:0071569 protein ufmylation(GO:0071569)
0.0 0.9 GO:0031167 rRNA methylation(GO:0031167)
0.0 0.1 GO:1902463 protein localization to cell leading edge(GO:1902463)
0.0 0.1 GO:0002940 tRNA N2-guanine methylation(GO:0002940)
0.0 0.1 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.0 0.3 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.2 GO:0042631 cellular response to water deprivation(GO:0042631)
0.0 0.1 GO:0072716 response to actinomycin D(GO:0072716) cellular response to actinomycin D(GO:0072717)
0.0 0.1 GO:0033686 positive regulation of luteinizing hormone secretion(GO:0033686)
0.0 0.7 GO:0044849 estrous cycle(GO:0044849)
0.0 0.4 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.0 0.1 GO:0046041 ITP metabolic process(GO:0046041)
0.0 0.1 GO:0019085 early viral transcription(GO:0019085)
0.0 0.1 GO:0050712 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.0 0.1 GO:0042350 GDP-L-fucose biosynthetic process(GO:0042350)
0.0 0.1 GO:2000793 cell proliferation involved in heart valve development(GO:2000793)
0.0 0.1 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.0 0.1 GO:1901873 regulation of post-translational protein modification(GO:1901873)
0.0 0.1 GO:0010897 negative regulation of triglyceride catabolic process(GO:0010897)
0.0 0.1 GO:0060032 notochord regression(GO:0060032)
0.0 0.1 GO:0034445 regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
0.0 0.4 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.0 0.3 GO:0018317 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0 0.1 GO:0039506 modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
0.0 0.1 GO:0051708 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0 0.1 GO:0051086 chaperone mediated protein folding independent of cofactor(GO:0051086)
0.0 0.0 GO:2001186 negative regulation of CD8-positive, alpha-beta T cell activation(GO:2001186)
0.0 0.1 GO:0072334 UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
0.0 0.1 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.0 0.5 GO:0035641 locomotory exploration behavior(GO:0035641)
0.0 0.2 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.0 0.1 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.0 0.1 GO:0006045 N-acetylglucosamine biosynthetic process(GO:0006045) glucosamine-containing compound biosynthetic process(GO:1901073)
0.0 0.1 GO:0002266 follicular dendritic cell activation(GO:0002266)
0.0 0.1 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.0 0.3 GO:0042908 xenobiotic transport(GO:0042908)
0.0 0.1 GO:0036511 trimming of terminal mannose on B branch(GO:0036509) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512)
0.0 0.1 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.1 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
0.0 0.2 GO:0010266 response to vitamin B1(GO:0010266)
0.0 0.2 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.1 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.0 0.2 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.1 GO:0051031 tRNA transport(GO:0051031)
0.0 0.2 GO:0044375 peroxisome membrane biogenesis(GO:0016557) regulation of peroxisome size(GO:0044375)
0.0 0.3 GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
0.0 0.1 GO:0045959 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959)
0.0 0.4 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.1 GO:0006427 histidyl-tRNA aminoacylation(GO:0006427)
0.0 0.1 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.0 0.1 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0 0.1 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.0 0.0 GO:0006829 zinc II ion transport(GO:0006829)
0.0 0.2 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.0 0.2 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.0 0.2 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.1 GO:0001878 response to yeast(GO:0001878)
0.0 0.0 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.0 0.3 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.1 GO:0043335 protein unfolding(GO:0043335)
0.0 0.1 GO:1905244 regulation of modification of synaptic structure(GO:1905244)
0.0 0.0 GO:0032661 regulation of interleukin-18 production(GO:0032661)
0.0 0.1 GO:0070670 response to interleukin-4(GO:0070670) cellular response to interleukin-4(GO:0071353)
0.0 0.0 GO:0007057 spindle assembly involved in female meiosis I(GO:0007057)
0.0 1.9 GO:0002292 T cell differentiation involved in immune response(GO:0002292)
0.0 0.1 GO:0036229 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.0 0.3 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.0 0.3 GO:0071420 cellular response to histamine(GO:0071420)
0.0 0.4 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.0 0.2 GO:1903943 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 0.2 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.4 GO:0032060 bleb assembly(GO:0032060)
0.0 0.1 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.1 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.0 0.1 GO:0090238 positive regulation of arachidonic acid secretion(GO:0090238)
0.0 0.0 GO:2000397 positive regulation of viral budding via host ESCRT complex(GO:1903774) regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
0.0 0.7 GO:0008334 histone mRNA metabolic process(GO:0008334)
0.0 0.0 GO:0034471 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
0.0 0.2 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.1 GO:0032687 negative regulation of interferon-alpha production(GO:0032687) interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354)
0.0 0.1 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.0 0.5 GO:0061641 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.1 GO:0071348 cellular response to interleukin-11(GO:0071348)
0.0 0.2 GO:1902222 L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.0 0.2 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.0 GO:0061566 dADP phosphorylation(GO:0006174) dGDP phosphorylation(GO:0006186) AMP phosphorylation(GO:0006756) CDP phosphorylation(GO:0061508) dAMP phosphorylation(GO:0061565) CMP phosphorylation(GO:0061566) dCMP phosphorylation(GO:0061567) GDP phosphorylation(GO:0061568) UDP phosphorylation(GO:0061569) dCDP phosphorylation(GO:0061570) TDP phosphorylation(GO:0061571)
0.0 0.1 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 0.2 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.3 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.0 0.2 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.0 GO:0046368 GDP-L-fucose metabolic process(GO:0046368)
0.0 0.1 GO:1902410 mitotic cytokinetic process(GO:1902410)
0.0 1.9 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.0 GO:1901076 positive regulation of engulfment of apoptotic cell(GO:1901076)
0.0 0.1 GO:0032264 IMP salvage(GO:0032264)
0.0 0.1 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.0 0.1 GO:0060671 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.0 0.2 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.3 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.1 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.0 0.2 GO:1903204 negative regulation of oxidative stress-induced neuron death(GO:1903204)
0.0 0.1 GO:0039689 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.0 0.1 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.1 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0 0.1 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.1 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.0 0.2 GO:0048505 regulation of development, heterochronic(GO:0040034) regulation of timing of cell differentiation(GO:0048505)
0.0 0.1 GO:1901655 cellular response to ketone(GO:1901655)
0.0 0.1 GO:0019542 acetate biosynthetic process(GO:0019413) acetyl-CoA biosynthetic process from acetate(GO:0019427) propionate metabolic process(GO:0019541) propionate biosynthetic process(GO:0019542)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0005683 U7 snRNP(GO:0005683)
0.1 0.4 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.0 0.2 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.0 0.1 GO:0032002 interleukin-28 receptor complex(GO:0032002)
0.0 0.3 GO:0036021 endolysosome lumen(GO:0036021)
0.0 0.3 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.2 GO:0031084 BLOC-2 complex(GO:0031084)
0.0 0.4 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.0 0.3 GO:0035976 AP1 complex(GO:0035976)
0.0 0.3 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 0.1 GO:0036502 Derlin-1-VIMP complex(GO:0036502)
0.0 0.1 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.0 0.1 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.0 0.3 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.0 0.2 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.3 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.2 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.0 0.2 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.1 GO:0071817 MMXD complex(GO:0071817)
0.0 0.1 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.0 0.7 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.3 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.1 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.0 0.2 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.4 GO:0042627 chylomicron(GO:0042627)
0.0 0.1 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.0 0.1 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.1 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.2 GO:0042382 paraspeckles(GO:0042382)
0.0 0.2 GO:0008278 cohesin complex(GO:0008278)
0.0 0.1 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.1 GO:0019815 B cell receptor complex(GO:0019815)
0.0 0.2 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.3 GO:0030914 STAGA complex(GO:0030914)
0.0 0.2 GO:0034464 BBSome(GO:0034464)
0.0 1.0 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.3 GO:0031265 CD95 death-inducing signaling complex(GO:0031265) ripoptosome(GO:0097342)
0.0 0.1 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.1 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.3 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.0 GO:0042585 germinal vesicle(GO:0042585)
0.0 1.4 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.1 GO:0034709 methylosome(GO:0034709)
0.0 0.0 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.1 0.6 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.1 0.4 GO:0004730 pseudouridylate synthase activity(GO:0004730)
0.1 0.5 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.1 0.6 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.1 2.2 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.1 0.5 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
0.1 0.2 GO:0034038 deoxyhypusine synthase activity(GO:0034038)
0.1 0.2 GO:0005427 proton-dependent oligopeptide secondary active transmembrane transporter activity(GO:0005427) secondary active oligopeptide transmembrane transporter activity(GO:0015322)
0.1 0.5 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.1 0.4 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.1 0.2 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.1 0.2 GO:0004967 glucagon receptor activity(GO:0004967)
0.1 0.2 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.0 0.2 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.0 0.1 GO:0004947 bradykinin receptor activity(GO:0004947)
0.0 0.1 GO:0004819 glutamine-tRNA ligase activity(GO:0004819)
0.0 0.2 GO:0016435 rRNA (guanine) methyltransferase activity(GO:0016435)
0.0 0.1 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.0 0.2 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.4 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.0 0.1 GO:0003863 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.0 0.1 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.0 0.1 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.0 0.4 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.1 GO:0001181 transcription factor activity, core RNA polymerase I binding(GO:0001181)
0.0 0.2 GO:1990446 U1 snRNP binding(GO:1990446)
0.0 0.1 GO:0009384 UDP-N-acetylglucosamine 2-epimerase activity(GO:0008761) N-acylmannosamine kinase activity(GO:0009384)
0.0 0.3 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.0 0.2 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.2 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.4 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.3 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.1 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.0 0.1 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.0 0.2 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 0.4 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.1 GO:0003974 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.0 0.3 GO:0001851 complement component C3b binding(GO:0001851)
0.0 0.2 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.0 0.1 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.0 0.2 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.0 0.3 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.1 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.0 0.1 GO:0004821 histidine-tRNA ligase activity(GO:0004821)
0.0 0.1 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263)
0.0 0.1 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.4 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.1 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.2 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.1 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.0 0.1 GO:0034603 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.0 0.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.1 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.0 0.1 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 0.1 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.1 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0 0.2 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.1 GO:0004883 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.1 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.1 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.2 GO:0043142 single-stranded DNA-dependent ATPase activity(GO:0043142)
0.0 0.0 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.0 0.1 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.0 0.5 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.2 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.0 GO:0008424 glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921)
0.0 0.1 GO:0019770 IgG receptor activity(GO:0019770)
0.0 0.1 GO:0047820 D-glutamate cyclase activity(GO:0047820)
0.0 0.0 GO:0090541 MIT domain binding(GO:0090541)
0.0 0.1 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 2.9 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.0 GO:0030943 mitochondrion targeting sequence binding(GO:0030943)
0.0 0.2 GO:0034452 dynactin binding(GO:0034452)
0.0 0.1 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.1 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 0.5 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.1 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 REACTOME SHC RELATED EVENTS Genes involved in SHC-related events
0.0 0.9 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 0.7 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 2.4 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.5 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.5 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.3 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.6 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.3 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.4 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.3 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 2.2 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.4 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.2 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.3 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.1 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.0 0.3 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation