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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for SRY

Z-value: 0.61

Motif logo

Transcription factors associated with SRY

Gene Symbol Gene ID Gene Info
ENSG00000184895.6 sex determining region Y

Activity profile of SRY motif

Sorted Z-values of SRY motif

Promoter Log-likelihood Transcript Gene Gene Info
chr10_-_105845674 4.74 ENST00000353479.5
ENST00000369733.3
collagen, type XVII, alpha 1
chr10_-_105845536 4.02 ENST00000393211.3
collagen, type XVII, alpha 1
chr3_+_189507460 3.95 ENST00000434928.1
tumor protein p63
chr3_+_189507523 3.77 ENST00000437221.1
ENST00000392463.2
ENST00000392461.3
ENST00000449992.1
ENST00000456148.1
tumor protein p63
chr3_+_189507432 3.03 ENST00000354600.5
tumor protein p63
chr12_-_28124903 2.19 ENST00000395872.1
ENST00000354417.3
ENST00000201015.4
parathyroid hormone-like hormone
chr14_+_37126765 2.14 ENST00000402703.2
paired box 9
chr8_-_124553437 2.03 ENST00000517956.1
ENST00000443022.2
F-box protein 32
chr3_-_71353892 2.03 ENST00000484350.1
forkhead box P1
chr6_-_56716686 2.02 ENST00000520645.1
dystonin
chr10_+_11206925 2.01 ENST00000354440.2
ENST00000315874.4
ENST00000427450.1
CUGBP, Elav-like family member 2
chr8_+_24151553 1.91 ENST00000265769.4
ENST00000540823.1
ENST00000397649.3
ADAM metallopeptidase domain 28
chr3_+_99357319 1.90 ENST00000452013.1
ENST00000261037.3
ENST00000273342.4
collagen, type VIII, alpha 1
chr1_-_39395165 1.88 ENST00000372985.3
rhomboid, veinlet-like 2 (Drosophila)
chr15_+_98503922 1.87 ENST00000268042.6
arrestin domain containing 4
chr11_-_125351481 1.84 ENST00000577924.1
fasciculation and elongation protein zeta 1 (zygin I)
chrM_-_14670 1.73 ENST00000361681.2
mitochondrially encoded NADH dehydrogenase 6
chr11_+_131781290 1.45 ENST00000425719.2
ENST00000374784.1
neurotrimin
chr4_-_68749745 1.37 ENST00000283916.6
transmembrane protease, serine 11D
chr7_+_134551583 1.33 ENST00000435928.1
caldesmon 1
chr11_-_10830463 1.31 ENST00000527419.1
ENST00000530211.1
ENST00000530702.1
ENST00000524932.1
ENST00000532570.1
eukaryotic translation initiation factor 4 gamma, 2
chr13_-_41240717 1.28 ENST00000379561.5
forkhead box O1
chr10_+_111967345 1.25 ENST00000332674.5
ENST00000453116.1
MAX interactor 1, dimerization protein
chr8_+_24151620 1.23 ENST00000437154.2
ADAM metallopeptidase domain 28
chr4_-_68749699 1.21 ENST00000545541.1
transmembrane protease, serine 11D
chr12_-_8815404 1.21 ENST00000359478.2
ENST00000396549.2
microfibrillar associated protein 5
chr10_+_24528108 1.16 ENST00000438429.1
KIAA1217
chr10_+_111985837 1.11 ENST00000393134.1
MAX interactor 1, dimerization protein
chr19_+_13134772 1.10 ENST00000587760.1
ENST00000585575.1
nuclear factor I/X (CCAAT-binding transcription factor)
chr1_-_40367668 1.09 ENST00000397332.2
ENST00000429311.1
v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
chr17_-_17875688 1.09 ENST00000379504.3
ENST00000318094.10
ENST00000540946.1
ENST00000542206.1
ENST00000395739.4
ENST00000581396.1
ENST00000535933.1
ENST00000579586.1
target of myb1-like 2 (chicken)
chr2_-_208030295 1.09 ENST00000458272.1
Kruppel-like factor 7 (ubiquitous)
chr12_-_8815215 1.08 ENST00000544889.1
ENST00000543369.1
microfibrillar associated protein 5
chr9_+_124461603 1.04 ENST00000373782.3
DAB2 interacting protein
chr13_+_110958124 1.01 ENST00000400163.2
collagen, type IV, alpha 2
chr12_-_8815299 0.99 ENST00000535336.1
microfibrillar associated protein 5
chr16_-_65106110 0.95 ENST00000562882.1
ENST00000567934.1
cadherin 11, type 2, OB-cadherin (osteoblast)
chr5_+_137673200 0.94 ENST00000434981.2
family with sequence similarity 53, member C
chr1_+_61547405 0.88 ENST00000371189.4
nuclear factor I/A
chr12_-_8815477 0.88 ENST00000433590.2
microfibrillar associated protein 5
chr8_-_42358742 0.88 ENST00000517366.1
solute carrier family 20 (phosphate transporter), member 2
chr21_-_32931290 0.87 ENST00000286827.3
T-cell lymphoma invasion and metastasis 1
chr9_+_132099158 0.87 ENST00000444125.1
RP11-65J3.1
chr2_+_27665232 0.87 ENST00000543753.1
ENST00000288873.3
keratinocyte associated protein 3
chr15_-_34610962 0.85 ENST00000290209.5
solute carrier family 12 (potassium/chloride transporter), member 6
chr17_+_1666108 0.84 ENST00000570731.1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr15_+_49715449 0.81 ENST00000560979.1
fibroblast growth factor 7
chr21_+_39628852 0.80 ENST00000398938.2
potassium inwardly-rectifying channel, subfamily J, member 15
chr2_-_163099885 0.80 ENST00000443424.1
fibroblast activation protein, alpha
chr2_-_37899323 0.79 ENST00000295324.3
ENST00000457889.1
CDC42 effector protein (Rho GTPase binding) 3
chr5_+_86563636 0.78 ENST00000274376.6
RAS p21 protein activator (GTPase activating protein) 1
chr2_-_163100045 0.76 ENST00000188790.4
fibroblast activation protein, alpha
chr21_-_19191703 0.76 ENST00000284881.4
ENST00000400559.3
ENST00000400558.3
chromosome 21 open reading frame 91
chr14_-_36990061 0.72 ENST00000546983.1
NK2 homeobox 1
chr4_-_140477910 0.72 ENST00000404104.3
SET domain containing (lysine methyltransferase) 7
chr10_-_62332357 0.70 ENST00000503366.1
ankyrin 3, node of Ranvier (ankyrin G)
chr10_+_111985713 0.69 ENST00000239007.7
MAX interactor 1, dimerization protein
chr13_-_74708372 0.67 ENST00000377666.4
Kruppel-like factor 12
chr3_+_41236325 0.66 ENST00000426215.1
ENST00000405570.1
catenin (cadherin-associated protein), beta 1, 88kDa
chr10_+_11207088 0.66 ENST00000608830.1
CUGBP, Elav-like family member 2
chr19_+_13135731 0.66 ENST00000587260.1
nuclear factor I/X (CCAAT-binding transcription factor)
chr5_+_137673945 0.64 ENST00000513056.1
ENST00000511276.1
family with sequence similarity 53, member C
chr3_+_57882061 0.64 ENST00000461354.1
ENST00000466255.1
sarcolemma associated protein
chr4_-_76598296 0.63 ENST00000395719.3
GTPase activating protein (SH3 domain) binding protein 2
chr2_+_27665289 0.62 ENST00000407293.1
keratinocyte associated protein 3
chr2_-_220042825 0.62 ENST00000409789.1
cyclin Pas1/PHO80 domain containing 1
chr19_+_13135790 0.62 ENST00000358552.3
nuclear factor I/X (CCAAT-binding transcription factor)
chr2_-_208030647 0.62 ENST00000309446.6
Kruppel-like factor 7 (ubiquitous)
chrX_+_9880412 0.61 ENST00000418909.2
shroom family member 2
chr3_-_58652523 0.61 ENST00000489857.1
ENST00000358781.2
family with sequence similarity 3, member D
chr11_+_128562372 0.59 ENST00000344954.6
Fli-1 proto-oncogene, ETS transcription factor
chr5_-_24645078 0.59 ENST00000264463.4
cadherin 10, type 2 (T2-cadherin)
chr18_-_53257027 0.58 ENST00000568740.1
ENST00000564403.2
ENST00000537578.1
transcription factor 4
chr11_-_10829851 0.57 ENST00000532082.1
eukaryotic translation initiation factor 4 gamma, 2
chr14_-_89960395 0.57 ENST00000555034.1
ENST00000553904.1
forkhead box N3
chr17_+_8924837 0.56 ENST00000173229.2
netrin 1
chr5_+_66254698 0.55 ENST00000405643.1
ENST00000407621.1
ENST00000432426.1
microtubule associated serine/threonine kinase family member 4
chr14_-_89883412 0.55 ENST00000557258.1
forkhead box N3
chr3_-_47205066 0.54 ENST00000412450.1
SET domain containing 2
chr1_-_115053781 0.53 ENST00000358465.2
ENST00000369543.2
tripartite motif containing 33
chr11_+_128563948 0.52 ENST00000534087.2
Fli-1 proto-oncogene, ETS transcription factor
chr4_-_76598544 0.52 ENST00000515457.1
ENST00000357854.3
GTPase activating protein (SH3 domain) binding protein 2
chr6_-_111888474 0.51 ENST00000368735.1
TRAF3 interacting protein 2
chr3_+_57741957 0.51 ENST00000295951.3
sarcolemma associated protein
chr5_-_41794663 0.50 ENST00000510634.1
3-oxoacid CoA transferase 1
chr3_+_28390637 0.50 ENST00000420223.1
ENST00000383768.2
zinc finger, CW type with PWWP domain 2
chr1_+_43855545 0.49 ENST00000372450.4
ENST00000310739.4
seizure threshold 2 homolog (mouse)
chr2_-_160473114 0.49 ENST00000392783.2
bromodomain adjacent to zinc finger domain, 2B
chr16_+_53920795 0.49 ENST00000431610.2
ENST00000460382.1
fat mass and obesity associated
chr4_+_71588372 0.48 ENST00000536664.1
RUN and FYVE domain containing 3
chr11_+_67007518 0.48 ENST00000530342.1
ENST00000308783.5
lysine (K)-specific demethylase 2A
chr8_+_21777243 0.47 ENST00000521303.1
exportin 7
chr7_+_128399002 0.47 ENST00000493278.1
calumenin
chr1_-_115292591 0.47 ENST00000438362.2
cold shock domain containing E1, RNA-binding
chr16_-_4852915 0.46 ENST00000322048.7
rogdi homolog (Drosophila)
chr1_-_40367530 0.46 ENST00000372816.2
ENST00000372815.1
v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
chr11_-_46141338 0.46 ENST00000529782.1
ENST00000532010.1
ENST00000525438.1
ENST00000533757.1
ENST00000527782.1
PHD finger protein 21A
chr4_-_53522703 0.46 ENST00000508499.1
ubiquitin specific peptidase 46
chr3_-_141868357 0.45 ENST00000489671.1
ENST00000475734.1
ENST00000467072.1
ENST00000499676.2
transcription factor Dp-2 (E2F dimerization partner 2)
chr10_+_11207438 0.44 ENST00000609692.1
ENST00000354897.3
CUGBP, Elav-like family member 2
chr3_+_57882024 0.44 ENST00000494088.1
sarcolemma associated protein
chr8_+_79503458 0.43 ENST00000518467.1
protein kinase (cAMP-dependent, catalytic) inhibitor alpha
chr18_+_46065483 0.43 ENST00000382998.4
CBP80/20-dependent translation initiation factor
chr1_-_93645818 0.42 ENST00000370280.1
ENST00000479918.1
transmembrane emp24 protein transport domain containing 5
chr7_+_30185406 0.42 ENST00000324489.5
maturin, neural progenitor differentiation regulator homolog (Xenopus)
chr3_-_69129501 0.41 ENST00000540295.1
ENST00000415609.2
ENST00000361055.4
ENST00000349511.4
ubiquitin-like modifier activating enzyme 3
chr12_+_130646999 0.40 ENST00000539839.1
ENST00000229030.4
frizzled family receptor 10
chr20_-_43150601 0.40 ENST00000541235.1
ENST00000255175.1
ENST00000342374.4
serine incorporator 3
chr6_-_134639042 0.39 ENST00000461976.2
serum/glucocorticoid regulated kinase 1
chr10_-_61900762 0.38 ENST00000355288.2
ankyrin 3, node of Ranvier (ankyrin G)
chr9_+_116343192 0.38 ENST00000471324.2
regulator of G-protein signaling 3
chr11_+_128563652 0.37 ENST00000527786.2
Fli-1 proto-oncogene, ETS transcription factor
chr16_+_53469525 0.37 ENST00000544405.2
retinoblastoma-like 2 (p130)
chr1_-_108231101 0.37 ENST00000544443.1
ENST00000415432.2
vav 3 guanine nucleotide exchange factor
chr11_-_13461790 0.36 ENST00000530907.1
BTB (POZ) domain containing 10
chrM_+_8527 0.36 ENST00000361899.2
mitochondrially encoded ATP synthase 6
chr1_+_100316041 0.36 ENST00000370165.3
ENST00000370163.3
ENST00000294724.4
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
chr2_-_160472952 0.35 ENST00000541068.2
ENST00000355831.2
ENST00000343439.5
ENST00000392782.1
bromodomain adjacent to zinc finger domain, 2B
chr13_-_46716969 0.35 ENST00000435666.2
lymphocyte cytosolic protein 1 (L-plastin)
chr7_-_140155711 0.35 ENST00000463142.1
makorin ring finger protein 1
chr7_+_30185496 0.35 ENST00000455738.1
maturin, neural progenitor differentiation regulator homolog (Xenopus)
chr12_-_49504449 0.35 ENST00000547675.1
limb development membrane protein 1-like
chr11_+_57529234 0.34 ENST00000360682.6
ENST00000361796.4
ENST00000529526.1
ENST00000426142.2
ENST00000399050.4
ENST00000361391.6
ENST00000361332.4
ENST00000532463.1
ENST00000529986.1
ENST00000358694.6
ENST00000532787.1
ENST00000533667.1
ENST00000532649.1
ENST00000528621.1
ENST00000530748.1
ENST00000428599.2
ENST00000527467.1
ENST00000528232.1
ENST00000531014.1
ENST00000526772.1
ENST00000529873.1
ENST00000525902.1
ENST00000532844.1
ENST00000526357.1
ENST00000530094.1
ENST00000415361.2
ENST00000532245.1
ENST00000534579.1
ENST00000526938.1
catenin (cadherin-associated protein), delta 1
chr4_-_111120132 0.34 ENST00000506625.1
ELOVL fatty acid elongase 6
chr12_-_76817036 0.34 ENST00000546946.1
oxysterol binding protein-like 8
chr1_-_53018654 0.34 ENST00000257177.4
ENST00000355809.4
ENST00000528642.1
ENST00000470626.1
ENST00000371544.3
zinc finger, CCHC domain containing 11
chr15_+_90544532 0.33 ENST00000268154.4
zinc finger protein 710
chr6_+_108882069 0.33 ENST00000406360.1
forkhead box O3
chr1_-_117210290 0.33 ENST00000369483.1
ENST00000369486.3
immunoglobulin superfamily, member 3
chr4_+_170581213 0.32 ENST00000507875.1
chloride channel, voltage-sensitive 3
chrX_+_107288280 0.32 ENST00000458383.1
V-set and immunoglobulin domain containing 1
chr8_-_116673894 0.32 ENST00000395713.2
trichorhinophalangeal syndrome I
chr3_-_141868293 0.31 ENST00000317104.7
ENST00000494358.1
transcription factor Dp-2 (E2F dimerization partner 2)
chr5_-_146461027 0.31 ENST00000394410.2
ENST00000508267.1
ENST00000504198.1
protein phosphatase 2, regulatory subunit B, beta
chr11_-_111637083 0.31 ENST00000427203.2
ENST00000341980.6
ENST00000311129.5
ENST00000393055.2
ENST00000426998.2
ENST00000527614.1
protein phosphatase 2, regulatory subunit A, beta
chr9_-_14314518 0.31 ENST00000397581.2
nuclear factor I/B
chr5_+_140743859 0.31 ENST00000518069.1
protocadherin gamma subfamily A, 5
chr14_-_61124977 0.31 ENST00000554986.1
SIX homeobox 1
chr8_-_101724989 0.30 ENST00000517403.1
poly(A) binding protein, cytoplasmic 1
chr11_+_110001723 0.30 ENST00000528673.1
zinc finger CCCH-type containing 12C
chr1_-_153931052 0.30 ENST00000368630.3
ENST00000368633.1
CREB regulated transcription coactivator 2
chr16_+_2587998 0.30 ENST00000441549.3
ENST00000268673.7
3-phosphoinositide dependent protein kinase-1
chr8_-_57123815 0.29 ENST00000316981.3
ENST00000423799.2
ENST00000429357.2
pleiomorphic adenoma gene 1
chr10_-_99094458 0.29 ENST00000371019.2
frequently rearranged in advanced T-cell lymphomas 2
chr12_-_31477072 0.29 ENST00000454658.2
family with sequence similarity 60, member A
chr18_+_46065570 0.29 ENST00000591412.1
CBP80/20-dependent translation initiation factor
chr1_+_43855560 0.29 ENST00000562955.1
seizure threshold 2 homolog (mouse)
chr9_-_14314566 0.29 ENST00000397579.2
nuclear factor I/B
chr3_+_57875711 0.28 ENST00000442599.2
sarcolemma associated protein
chrX_-_106959631 0.28 ENST00000486554.1
ENST00000372390.4
TSC22 domain family, member 3
chr15_-_70390213 0.28 ENST00000557997.1
ENST00000317509.8
ENST00000442299.2
transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)
chrM_+_8366 0.28 ENST00000361851.1
mitochondrially encoded ATP synthase 8
chr8_+_57124245 0.27 ENST00000521831.1
ENST00000355315.3
ENST00000303759.3
ENST00000517636.1
ENST00000517933.1
ENST00000518801.1
ENST00000523975.1
ENST00000396723.5
ENST00000523061.1
ENST00000521524.1
coiled-coil-helix-coiled-coil-helix domain containing 7
chr6_+_126070726 0.26 ENST00000368364.3
hes-related family bHLH transcription factor with YRPW motif 2
chr7_+_151038850 0.26 ENST00000355851.4
ENST00000566856.1
ENST00000470229.1
negative regulator of ubiquitin-like proteins 1
chr11_+_120255997 0.26 ENST00000532993.1
Rho guanine nucleotide exchange factor (GEF) 12
chr10_+_11207485 0.26 ENST00000537122.1
CUGBP, Elav-like family member 2
chr16_+_28857916 0.26 ENST00000563591.1
SH2B adaptor protein 1
chr11_+_28724129 0.26 ENST00000513853.1
RP11-115J23.1
chr4_-_76598326 0.25 ENST00000503660.1
GTPase activating protein (SH3 domain) binding protein 2
chr20_-_35492048 0.25 ENST00000237536.4
suppressor of glucose, autophagy associated 1
chr12_-_498415 0.25 ENST00000535014.1
ENST00000543507.1
ENST00000544760.1
lysine (K)-specific demethylase 5A
chr10_-_104913367 0.24 ENST00000423468.2
5'-nucleotidase, cytosolic II
chr1_-_8075693 0.24 ENST00000467067.1
ERBB receptor feedback inhibitor 1
chr12_+_95611536 0.24 ENST00000549002.1
vezatin, adherens junctions transmembrane protein
chr11_+_57435219 0.23 ENST00000527985.1
ENST00000287169.3
zinc finger, DHHC-type containing 5
chr13_+_102142296 0.23 ENST00000376162.3
integrin, beta-like 1 (with EGF-like repeat domains)
chr20_-_52612705 0.23 ENST00000434986.2
breast carcinoma amplified sequence 1
chr4_-_103746924 0.23 ENST00000505207.1
ENST00000502404.1
ENST00000507845.1
ubiquitin-conjugating enzyme E2D 3
chr8_-_71157595 0.23 ENST00000519724.1
nuclear receptor coactivator 2
chr14_-_73493784 0.23 ENST00000553891.1
zinc finger, FYVE domain containing 1
chr7_+_142985467 0.22 ENST00000392925.2
caspase 2, apoptosis-related cysteine peptidase
chr16_+_2588012 0.22 ENST00000354836.5
ENST00000389224.3
3-phosphoinositide dependent protein kinase-1
chr1_+_40840320 0.22 ENST00000372708.1
small ArfGAP2
chr19_+_13906250 0.22 ENST00000254323.2
zinc finger, SWIM-type containing 4
chr6_+_157099036 0.22 ENST00000350026.5
ENST00000346085.5
ENST00000367148.1
ENST00000275248.4
AT rich interactive domain 1B (SWI1-like)
chr18_+_55712915 0.22 ENST00000592846.1
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr15_-_55562451 0.21 ENST00000568803.1
RAB27A, member RAS oncogene family
chr2_-_207078086 0.21 ENST00000442134.1
G protein-coupled receptor 1
chr5_-_131132658 0.21 ENST00000514667.1
ENST00000511848.1
ENST00000510461.1
Folliculin-interacting protein 1
folliculin interacting protein 1
chrX_+_9880590 0.20 ENST00000452575.1
shroom family member 2
chr4_-_103747011 0.20 ENST00000350435.7
ubiquitin-conjugating enzyme E2D 3
chr20_-_61002584 0.20 ENST00000252998.1
RBBP8 N-terminal like
chr12_+_60058458 0.20 ENST00000548610.1
solute carrier family 16 (monocarboxylate transporter), member 7
chr5_-_88120083 0.20 ENST00000509373.1
myocyte enhancer factor 2C
chr2_+_208423891 0.20 ENST00000448277.1
ENST00000457101.1
cAMP responsive element binding protein 1
chr14_-_73493825 0.19 ENST00000318876.5
ENST00000556143.1
zinc finger, FYVE domain containing 1
chr6_-_163148780 0.19 ENST00000366892.1
ENST00000366898.1
ENST00000366897.1
ENST00000366896.1
parkin RBR E3 ubiquitin protein ligase
chr6_+_53794780 0.19 ENST00000505762.1
ENST00000511369.1
ENST00000431554.2
muscular LMNA-interacting protein
RP11-411K7.1
chr12_-_53994805 0.19 ENST00000328463.7
activating transcription factor 7
chr12_+_42725554 0.19 ENST00000546750.1
ENST00000547847.1
periphilin 1
chr3_+_141596371 0.19 ENST00000495216.1
ATPase, Na+/K+ transporting, beta 3 polypeptide
chr15_+_91416092 0.18 ENST00000559353.1
furin (paired basic amino acid cleaving enzyme)
chr2_+_162087577 0.18 ENST00000439442.1
TRAF family member-associated NFKB activator
chr4_-_140477928 0.18 ENST00000274031.3
SET domain containing (lysine methyltransferase) 7
chr4_-_103746683 0.18 ENST00000504211.1
ENST00000508476.1
ubiquitin-conjugating enzyme E2D 3
chr2_-_163099546 0.18 ENST00000447386.1
fibroblast activation protein, alpha
chr12_+_95611569 0.17 ENST00000261219.6
ENST00000551472.1
ENST00000552821.1
vezatin, adherens junctions transmembrane protein
chr4_-_185395191 0.17 ENST00000510814.1
ENST00000507523.1
ENST00000506230.1
interferon regulatory factor 2
chr16_+_2587965 0.17 ENST00000342085.4
ENST00000566659.1
3-phosphoinositide dependent protein kinase-1

Network of associatons between targets according to the STRING database.

First level regulatory network of SRY

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 10.8 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.6 1.7 GO:1902362 melanocyte apoptotic process(GO:1902362)
0.3 2.0 GO:0072619 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.3 0.8 GO:0008057 eye pigment granule organization(GO:0008057)
0.2 8.8 GO:0031581 hemidesmosome assembly(GO:0031581)
0.2 1.9 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.2 1.8 GO:0045631 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.2 1.3 GO:0035947 regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter(GO:0035947)
0.2 1.0 GO:0043553 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324) negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.2 1.2 GO:1900827 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.2 0.5 GO:0097198 histone H3-K36 trimethylation(GO:0097198)
0.2 0.9 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.2 0.7 GO:1904499 glial cell fate determination(GO:0007403) canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324) regulation of chromatin-mediated maintenance of transcription(GO:1904499) positive regulation of chromatin-mediated maintenance of transcription(GO:1904501) regulation of euchromatin binding(GO:1904793)
0.2 0.5 GO:0042245 RNA repair(GO:0042245)
0.1 0.9 GO:1900147 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.1 0.4 GO:0007113 endomitotic cell cycle(GO:0007113)
0.1 2.0 GO:0008090 retrograde axonal transport(GO:0008090)
0.1 1.8 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.1 0.8 GO:0071279 cellular response to cobalt ion(GO:0071279)
0.1 0.8 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.1 0.3 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.1 2.0 GO:0014894 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.1 4.4 GO:0042994 cytoplasmic sequestering of transcription factor(GO:0042994)
0.1 0.6 GO:0060437 lung growth(GO:0060437)
0.1 0.3 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
0.1 0.4 GO:0034721 histone H3-K4 demethylation, trimethyl-H3-K4-specific(GO:0034721)
0.1 1.2 GO:0048706 embryonic skeletal system development(GO:0048706)
0.1 4.1 GO:0060216 definitive hemopoiesis(GO:0060216)
0.1 0.3 GO:2000729 positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.1 0.2 GO:1904017 cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.1 0.6 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.1 0.6 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.1 0.8 GO:0021759 globus pallidus development(GO:0021759)
0.1 2.2 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.1 0.9 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.1 0.5 GO:0046952 ketone body catabolic process(GO:0046952)
0.1 0.2 GO:0019082 viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.1 3.2 GO:0006376 mRNA splice site selection(GO:0006376)
0.1 1.1 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.1 0.3 GO:0048388 endosomal lumen acidification(GO:0048388)
0.1 0.8 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.1 0.7 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.1 1.5 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.4 GO:0009597 detection of virus(GO:0009597)
0.0 0.9 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 1.8 GO:0042481 regulation of odontogenesis(GO:0042481)
0.0 1.0 GO:0021957 corticospinal tract morphogenesis(GO:0021957)
0.0 0.3 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.0 3.0 GO:0035987 endodermal cell differentiation(GO:0035987)
0.0 0.9 GO:0072189 ureter development(GO:0072189)
0.0 0.3 GO:0032808 lacrimal gland development(GO:0032808)
0.0 0.4 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.0 0.4 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.2 GO:0003172 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.0 0.3 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.2 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.3 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.0 0.2 GO:1904550 chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.0 0.3 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.2 GO:1903288 positive regulation of potassium ion import(GO:1903288)
0.0 0.4 GO:0060013 righting reflex(GO:0060013)
0.0 0.3 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.2 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 1.7 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.2 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 0.7 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.5 GO:0016337 single organismal cell-cell adhesion(GO:0016337)
0.0 0.4 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 0.2 GO:1903243 negative regulation of cardiac muscle adaptation(GO:0010616) lung vasculature development(GO:0060426) negative regulation of cardiac muscle hypertrophy in response to stress(GO:1903243)
0.0 0.4 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.1 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.0 0.1 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0 0.6 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 1.7 GO:0007585 respiratory gaseous exchange(GO:0007585)
0.0 0.3 GO:0060736 prostate gland growth(GO:0060736)
0.0 0.5 GO:0001783 B cell apoptotic process(GO:0001783)
0.0 0.1 GO:0060686 regulation of prostatic bud formation(GO:0060685) negative regulation of prostatic bud formation(GO:0060686)
0.0 0.3 GO:0035635 entry of bacterium into host cell(GO:0035635)
0.0 0.3 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.0 0.3 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.0 1.6 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.8 GO:0010107 potassium ion import(GO:0010107)
0.0 0.4 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.2 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.0 0.2 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.1 GO:0021800 cerebral cortex tangential migration(GO:0021800)
0.0 1.1 GO:0045839 negative regulation of mitotic nuclear division(GO:0045839)
0.0 0.2 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.4 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.4 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.0 0.8 GO:1900740 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.0 0.5 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.3 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.0 0.1 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.0 0.3 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 0.3 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 1.9 GO:0051443 positive regulation of ubiquitin-protein transferase activity(GO:0051443)
0.0 0.1 GO:0060484 lung-associated mesenchyme development(GO:0060484)
0.0 0.7 GO:0008038 neuron recognition(GO:0008038)
0.0 0.8 GO:0000281 mitotic cytokinesis(GO:0000281)
0.0 0.1 GO:0060023 soft palate development(GO:0060023)
0.0 0.1 GO:0051138 positive regulation of NK T cell differentiation(GO:0051138)
0.0 0.1 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 10.8 GO:0030056 hemidesmosome(GO:0030056)
0.3 1.0 GO:1990032 parallel fiber(GO:1990032)
0.3 2.9 GO:0098642 network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.2 4.1 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.1 0.8 GO:1990130 Iml1 complex(GO:1990130)
0.1 1.7 GO:0071438 invadopodium membrane(GO:0071438)
0.1 0.4 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.1 1.3 GO:0030478 actin cap(GO:0030478)
0.1 0.7 GO:0071664 Scrib-APC-beta-catenin complex(GO:0034750) beta-catenin-TCF7L2 complex(GO:0070369) catenin-TCF7L2 complex(GO:0071664)
0.1 10.7 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 1.9 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.5 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 1.2 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.6 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.8 GO:0043203 axon hillock(GO:0043203)
0.0 1.9 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.4 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.6 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.0 0.6 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.2 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.5 GO:0071437 invadopodium(GO:0071437)
0.0 2.0 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.2 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.3 GO:0005915 zonula adherens(GO:0005915)
0.0 0.6 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.4 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.2 GO:0005771 multivesicular body(GO:0005771)
0.0 1.7 GO:0070469 respiratory chain(GO:0070469)
0.0 0.1 GO:0072487 MSL complex(GO:0072487)
0.0 0.4 GO:0001891 phagocytic cup(GO:0001891)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 10.8 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.2 0.7 GO:0004676 3-phosphoinositide-dependent protein kinase activity(GO:0004676)
0.1 1.0 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.1 0.4 GO:0019781 NEDD8 activating enzyme activity(GO:0019781)
0.1 0.5 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.1 0.5 GO:0035514 DNA demethylase activity(GO:0035514)
0.1 0.9 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.1 0.4 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.1 0.2 GO:0050146 nucleoside phosphotransferase activity(GO:0050146)
0.1 0.3 GO:0035939 microsatellite binding(GO:0035939)
0.1 0.9 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 1.0 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.1 1.7 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 2.2 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.1 0.3 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.1 0.3 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 1.1 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 1.8 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.2 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0 3.2 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.2 GO:0010861 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.8 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 5.2 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.3 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 1.9 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 1.3 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.5 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.4 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.8 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.2 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.3 GO:0043426 MRF binding(GO:0043426)
0.0 0.4 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.0 0.6 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.8 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 2.4 GO:0050681 androgen receptor binding(GO:0050681)
0.0 1.2 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 1.7 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 1.8 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.2 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 0.4 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.4 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.1 GO:0004977 melanocortin receptor activity(GO:0004977)
0.0 0.6 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 3.0 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.4 GO:0042923 neuropeptide binding(GO:0042923)
0.0 1.2 GO:0030507 spectrin binding(GO:0030507)
0.0 0.8 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.4 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.4 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 1.4 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.3 GO:0008494 translation activator activity(GO:0008494)
0.0 0.2 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.9 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 3.5 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.3 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.1 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.7 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.4 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.3 GO:0017081 chloride channel regulator activity(GO:0017081)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 11.7 NABA COLLAGENS Genes encoding collagen proteins
0.1 11.8 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 5.0 PID FOXO PATHWAY FoxO family signaling
0.0 4.1 PID NOTCH PATHWAY Notch signaling pathway
0.0 1.5 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.0 1.3 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.8 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.6 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 2.6 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 1.0 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.7 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.5 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.6 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.6 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.9 PID P53 REGULATION PATHWAY p53 pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 11.5 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 2.3 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 0.7 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.0 0.8 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.7 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 1.2 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.4 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 2.5 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.6 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.3 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.3 REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.0 1.5 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 1.9 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.6 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.7 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.4 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.2 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.4 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.4 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.2 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.4 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1