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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for STAT1_STAT3_BCL6

Z-value: 1.77

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Transcription factors associated with STAT1_STAT3_BCL6

Gene Symbol Gene ID Gene Info
ENSG00000115415.14 signal transducer and activator of transcription 1
ENSG00000168610.10 signal transducer and activator of transcription 3
ENSG00000113916.13 BCL6 transcription repressor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
BCL6hg19_v2_chr3_-_187454281_187454357-0.912.0e-08Click!
STAT3hg19_v2_chr17_-_40540586_405406000.623.6e-03Click!
STAT1hg19_v2_chr2_-_191878874_1918789760.578.6e-03Click!

Activity profile of STAT1_STAT3_BCL6 motif

Sorted Z-values of STAT1_STAT3_BCL6 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr17_+_32582293 16.80 ENST00000580907.1
ENST00000225831.4
chemokine (C-C motif) ligand 2
chr4_-_155511887 13.25 ENST00000302053.3
ENST00000403106.3
fibrinogen alpha chain
chr17_-_46692287 8.38 ENST00000239144.4
homeobox B8
chr8_-_27469196 8.33 ENST00000546343.1
ENST00000560566.1
clusterin
chr2_+_87754989 7.86 ENST00000409898.2
ENST00000419680.2
ENST00000414584.1
ENST00000455131.1
long intergenic non-protein coding RNA 152
chr17_-_46691990 7.44 ENST00000576562.1
homeobox B8
chr15_-_88799661 7.35 ENST00000360948.2
ENST00000357724.2
ENST00000355254.2
ENST00000317501.3
neurotrophic tyrosine kinase, receptor, type 3
chr8_-_27468945 7.19 ENST00000405140.3
clusterin
chr8_-_27468842 7.03 ENST00000523500.1
clusterin
chr17_+_6347761 6.62 ENST00000250056.8
ENST00000571373.1
ENST00000570337.2
ENST00000572595.2
ENST00000576056.1
family with sequence similarity 64, member A
chr17_+_77021702 6.40 ENST00000392445.2
ENST00000354124.3
C1q and tumor necrosis factor related protein 1
chr9_+_97766409 6.12 ENST00000425634.2
chromosome 9 open reading frame 3
chr17_-_26697304 6.09 ENST00000536498.1
vitronectin
chr10_+_6625605 6.07 ENST00000414894.1
ENST00000449648.1
PRKCQ antisense RNA 1
chr3_-_148939835 5.90 ENST00000264613.6
ceruloplasmin (ferroxidase)
chr8_-_27468717 5.88 ENST00000520796.1
ENST00000520491.1
clusterin
chr9_-_75567962 5.84 ENST00000297785.3
ENST00000376939.1
aldehyde dehydrogenase 1 family, member A1
chr5_-_140013275 5.39 ENST00000512545.1
ENST00000302014.6
ENST00000401743.2
CD14 molecule
chr17_-_76356148 5.37 ENST00000587578.1
ENST00000330871.2
suppressor of cytokine signaling 3
chr17_+_6347729 5.22 ENST00000572447.1
family with sequence similarity 64, member A
chr12_+_53443963 5.14 ENST00000546602.1
ENST00000552570.1
ENST00000549700.1
tensin like C1 domain containing phosphatase (tensin 2)
chr8_-_27469383 4.95 ENST00000519742.1
clusterin
chr19_-_58864848 4.80 ENST00000263100.3
alpha-1-B glycoprotein
chr7_-_108096822 4.78 ENST00000379028.3
ENST00000413765.2
ENST00000379022.4
neuronal cell adhesion molecule
chr3_-_148939598 4.77 ENST00000455472.3
ceruloplasmin (ferroxidase)
chr8_+_71485681 4.55 ENST00000391684.1
AC120194.1
chr12_+_53443680 4.55 ENST00000314250.6
ENST00000451358.1
tensin like C1 domain containing phosphatase (tensin 2)
chr10_+_35484793 4.55 ENST00000488741.1
ENST00000474931.1
ENST00000468236.1
ENST00000344351.5
ENST00000490511.1
cAMP responsive element modulator
chr2_+_87755054 4.39 ENST00000423846.1
long intergenic non-protein coding RNA 152
chr10_+_6625733 4.36 ENST00000607982.1
ENST00000608526.1
PRKCQ antisense RNA 1
chr3_-_93692681 4.32 ENST00000348974.4
protein S (alpha)
chr12_+_122064398 4.30 ENST00000330079.7
ORAI calcium release-activated calcium modulator 1
chr12_+_122064673 4.27 ENST00000537188.1
ORAI calcium release-activated calcium modulator 1
chr4_+_15779901 4.23 ENST00000226279.3
CD38 molecule
chr2_+_87754887 4.22 ENST00000409054.1
ENST00000331944.6
ENST00000409139.1
long intergenic non-protein coding RNA 152
chr19_-_51875894 4.14 ENST00000600427.1
ENST00000595217.1
ENST00000221978.5
natural killer cell group 7 sequence
chr7_-_108096765 4.13 ENST00000379024.4
ENST00000351718.4
neuronal cell adhesion molecule
chr1_-_153521597 4.04 ENST00000368712.1
S100 calcium binding protein A3
chr12_-_7244469 4.03 ENST00000538050.1
ENST00000536053.2
complement component 1, r subcomponent
chr12_-_7245018 4.02 ENST00000543835.1
ENST00000535233.2
complement component 1, r subcomponent
chr14_-_80678512 3.94 ENST00000553968.1
deiodinase, iodothyronine, type II
chr6_+_32821924 3.91 ENST00000374859.2
ENST00000453265.2
proteasome (prosome, macropain) subunit, beta type, 9
chr22_-_31503490 3.87 ENST00000400299.2
Selenoprotein M
chr11_-_115127611 3.54 ENST00000545094.1
cell adhesion molecule 1
chr15_-_88799384 3.35 ENST00000540489.2
ENST00000557856.1
ENST00000558676.1
neurotrophic tyrosine kinase, receptor, type 3
chr5_-_140013224 3.30 ENST00000498971.2
CD14 molecule
chr1_-_8000872 3.29 ENST00000377507.3
tumor necrosis factor receptor superfamily, member 9
chr4_-_175443943 3.26 ENST00000296522.6
hydroxyprostaglandin dehydrogenase 15-(NAD)
chr11_+_7618413 3.24 ENST00000528883.1
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr4_-_155533787 3.23 ENST00000407946.1
ENST00000405164.1
ENST00000336098.3
ENST00000393846.2
ENST00000404648.3
ENST00000443553.1
fibrinogen gamma chain
chr4_+_155484103 3.19 ENST00000302068.4
fibrinogen beta chain
chr1_-_153521714 3.17 ENST00000368713.3
S100 calcium binding protein A3
chr4_+_155484155 3.16 ENST00000509493.1
fibrinogen beta chain
chr11_+_57531292 3.15 ENST00000524579.1
catenin (cadherin-associated protein), delta 1
chr11_+_46740730 3.13 ENST00000311907.5
ENST00000530231.1
ENST00000442468.1
coagulation factor II (thrombin)
chr4_+_41258786 3.13 ENST00000503431.1
ENST00000284440.4
ENST00000508768.1
ENST00000512788.1
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr22_+_24990746 3.13 ENST00000456869.1
ENST00000411974.1
gamma-glutamyltransferase 1
chr17_+_36858694 3.09 ENST00000563897.1
CTB-58E17.1
chr1_-_230850043 3.04 ENST00000366667.4
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr14_-_30396948 3.03 ENST00000331968.5
protein kinase D1
chr3_-_149095652 2.83 ENST00000305366.3
transmembrane 4 L six family member 1
chr16_-_8955601 2.80 ENST00000569398.1
ENST00000568968.1
calcium regulated heat stable protein 1, 24kDa
chr14_+_32414059 2.75 ENST00000553330.1
Uncharacterized protein
chr11_+_844067 2.65 ENST00000397406.1
ENST00000409543.2
ENST00000525201.1
tetraspanin 4
chrX_-_2882296 2.65 ENST00000438544.1
ENST00000381134.3
ENST00000545496.1
arylsulfatase E (chondrodysplasia punctata 1)
chr2_-_190044480 2.64 ENST00000374866.3
collagen, type V, alpha 2
chr3_-_120400960 2.62 ENST00000476082.2
homogentisate 1,2-dioxygenase
chrX_-_139866723 2.54 ENST00000370532.2
cerebellar degeneration-related protein 1, 34kDa
chr12_+_93964746 2.52 ENST00000536696.2
suppressor of cytokine signaling 2
chr19_-_49339732 2.51 ENST00000599157.1
hydroxysteroid (17-beta) dehydrogenase 14
chr16_+_30996502 2.49 ENST00000353250.5
ENST00000262520.6
ENST00000297679.5
ENST00000562932.1
ENST00000574447.1
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
chr5_-_38845812 2.44 ENST00000513480.1
ENST00000512519.1
CTD-2127H9.1
chr17_+_76356516 2.43 ENST00000592569.1
RP11-806H10.4
chr1_-_94374946 2.39 ENST00000370238.3
glutamate-cysteine ligase, modifier subunit
chr14_-_25519095 2.36 ENST00000419632.2
ENST00000358326.2
ENST00000396700.1
ENST00000548724.1
syntaxin binding protein 6 (amisyn)
chrX_-_10544942 2.35 ENST00000380779.1
midline 1 (Opitz/BBB syndrome)
chr7_-_74267836 2.33 ENST00000361071.5
ENST00000453619.2
ENST00000417115.2
ENST00000405086.2
GTF2I repeat domain containing 2
chr11_+_73003824 2.33 ENST00000538328.1
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr1_+_153631130 2.32 ENST00000368685.5
SNAP-associated protein
chr9_-_123812542 2.28 ENST00000223642.1
complement component 5
chr1_+_221051699 2.25 ENST00000366903.6
H2.0-like homeobox
chr11_+_76493294 2.25 ENST00000533752.1
tsukushi, small leucine rich proteoglycan
chr1_+_154300217 2.20 ENST00000368489.3
ATPase, aminophospholipid transporter, class I, type 8B, member 2
chr5_-_140013241 2.16 ENST00000519715.1
CD14 molecule
chr19_-_49339915 2.11 ENST00000263278.4
hydroxysteroid (17-beta) dehydrogenase 14
chr2_-_84686552 2.09 ENST00000393868.2
succinate-CoA ligase, alpha subunit
chr9_-_99180597 2.08 ENST00000375256.4
zinc finger protein 367
chr19_-_45927622 2.07 ENST00000300853.3
ENST00000589165.1
excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
chr19_+_18530146 2.04 ENST00000348495.6
ENST00000270061.7
single stranded DNA binding protein 4
chr19_+_35168567 2.04 ENST00000457781.2
ENST00000505163.1
ENST00000505242.1
ENST00000423823.2
ENST00000507959.1
ENST00000446502.2
zinc finger protein 302
chr14_+_76452090 2.03 ENST00000314067.6
ENST00000238628.6
ENST00000556742.1
intraflagellar transport 43 homolog (Chlamydomonas)
chr19_+_15218180 2.03 ENST00000342784.2
ENST00000597977.1
ENST00000600440.1
synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
chr17_+_48624450 1.99 ENST00000006658.6
ENST00000356488.4
ENST00000393244.3
spermatogenesis associated 20
chr3_-_186080012 1.97 ENST00000544847.1
ENST00000265022.3
diacylglycerol kinase, gamma 90kDa
chr19_+_35168547 1.97 ENST00000502743.1
ENST00000509528.1
ENST00000506901.1
zinc finger protein 302
chr8_-_102803163 1.95 ENST00000523645.1
ENST00000520346.1
ENST00000220931.6
ENST00000522448.1
ENST00000522951.1
ENST00000522252.1
ENST00000519098.1
neurocalcin delta
chr16_-_74734672 1.94 ENST00000306247.7
ENST00000575686.1
mixed lineage kinase domain-like
chrX_-_62571187 1.92 ENST00000335144.3
spindlin family, member 4
chr19_+_35485682 1.88 ENST00000599564.1
GRAM domain containing 1A
chr17_-_34207295 1.88 ENST00000463941.1
ENST00000293272.3
chemokine (C-C motif) ligand 5
chr2_-_167232484 1.87 ENST00000375387.4
ENST00000303354.6
ENST00000409672.1
sodium channel, voltage-gated, type IX, alpha subunit
chr19_+_35225060 1.87 ENST00000599244.1
ENST00000392232.3
zinc finger protein 181
chr19_-_40324255 1.86 ENST00000593685.1
ENST00000600611.1
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
chr19_-_40324767 1.84 ENST00000601972.1
ENST00000430012.2
ENST00000323039.5
ENST00000348817.3
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
chr10_-_33625154 1.83 ENST00000265371.4
neuropilin 1
chr11_+_62652649 1.83 ENST00000539507.1
solute carrier family 3 (amino acid transporter heavy chain), member 2
chr8_+_31497271 1.82 ENST00000520407.1
neuregulin 1
chr17_+_2264983 1.82 ENST00000574650.1
small G protein signaling modulator 2
chr15_+_76030311 1.78 ENST00000543887.1
AC019294.1
chrX_+_129473916 1.77 ENST00000545805.1
ENST00000543953.1
ENST00000218197.5
solute carrier family 25 (mitochondrial carrier, brain), member 14
chr20_+_42984330 1.75 ENST00000316673.4
ENST00000609795.1
ENST00000457232.1
ENST00000609262.1
hepatocyte nuclear factor 4, alpha
chr19_+_35168633 1.75 ENST00000505365.2
zinc finger protein 302
chr20_-_43280361 1.74 ENST00000372874.4
adenosine deaminase
chr5_-_67730240 1.73 ENST00000507733.1
CTC-537E7.3
chr2_+_97203082 1.72 ENST00000454558.2
AT rich interactive domain 5A (MRF1-like)
chr12_+_7023491 1.71 ENST00000541477.1
ENST00000229277.1
enolase 2 (gamma, neuronal)
chr16_-_3030407 1.69 ENST00000431515.2
ENST00000574385.1
ENST00000576268.1
ENST00000574730.1
ENST00000575632.1
ENST00000573944.1
ENST00000262300.8
protein kinase, membrane associated tyrosine/threonine 1
chr17_-_19265982 1.67 ENST00000268841.6
ENST00000261499.4
ENST00000575478.1
B9 protein domain 1
chr12_+_21679220 1.67 ENST00000256969.2
chromosome 12 open reading frame 39
chr3_-_93692781 1.66 ENST00000394236.3
protein S (alpha)
chr17_+_76311791 1.62 ENST00000586321.1
AC061992.2
chr6_+_44194762 1.59 ENST00000371708.1
solute carrier family 29 (equilibrative nucleoside transporter), member 1
chr17_-_76183111 1.59 ENST00000405273.1
ENST00000590862.1
ENST00000590430.1
ENST00000586613.1
thymidine kinase 1, soluble
chr2_-_175499294 1.58 ENST00000392547.2
WAS/WASL interacting protein family, member 1
chr15_+_57998923 1.58 ENST00000380557.4
polymerase (RNA) II (DNA directed) polypeptide M
chr17_+_43239231 1.57 ENST00000591576.1
ENST00000591070.1
ENST00000592695.1
hexamethylene bis-acetamide inducible 2
chr6_-_127840453 1.57 ENST00000556132.1
SOGA family member 3
chr4_+_41614720 1.56 ENST00000509277.1
LIM and calponin homology domains 1
chr4_-_140005443 1.56 ENST00000510408.1
ENST00000420916.2
ENST00000358635.3
E74-like factor 2 (ets domain transcription factor)
chr14_+_56127989 1.56 ENST00000555573.1
kinectin 1 (kinesin receptor)
chr11_-_62609281 1.54 ENST00000525239.1
ENST00000538098.2
WD repeat domain 74
chr4_+_169575875 1.54 ENST00000503457.1
palladin, cytoskeletal associated protein
chr1_+_213123915 1.52 ENST00000366968.4
ENST00000490792.1
vasohibin 2
chr4_-_140005341 1.51 ENST00000379549.2
ENST00000512627.1
E74-like factor 2 (ets domain transcription factor)
chr17_-_19265855 1.51 ENST00000440841.1
ENST00000395615.1
ENST00000461069.2
B9 protein domain 1
chr2_-_99917639 1.49 ENST00000308528.4
lysozyme G-like 1
chr16_-_57836321 1.49 ENST00000569112.1
ENST00000562311.1
ENST00000445690.2
ENST00000379655.4
kinesin family member C3
chr1_-_23520755 1.48 ENST00000314113.3
5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled
chr3_+_160117062 1.48 ENST00000497311.1
structural maintenance of chromosomes 4
chr6_-_127840021 1.47 ENST00000465909.2
SOGA family member 3
chr5_-_146781153 1.46 ENST00000520473.1
dihydropyrimidinase-like 3
chr2_-_233877912 1.46 ENST00000264051.3
neuronal guanine nucleotide exchange factor
chr6_-_127840336 1.45 ENST00000525778.1
SOGA family member 3
chr16_+_14396121 1.44 ENST00000570945.1
RP11-65J21.3
chr19_-_47231216 1.42 ENST00000594287.2
striatin, calmodulin binding protein 4
chr20_+_48909240 1.42 ENST00000371639.3
RP11-290F20.1
chr1_-_23521222 1.41 ENST00000374619.1
5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled
chr19_+_42746927 1.39 ENST00000378108.1
AC006486.1
chr19_+_51153045 1.38 ENST00000458538.1
chromosome 19 open reading frame 81
chr17_-_46692457 1.38 ENST00000468443.1
homeobox B8
chr15_+_78857870 1.37 ENST00000559554.1
cholinergic receptor, nicotinic, alpha 5 (neuronal)
chr3_+_44840679 1.37 ENST00000425755.1
kinesin family member 15
chrX_-_62571220 1.37 ENST00000374884.2
spindlin family, member 4
chr16_-_8955570 1.36 ENST00000567554.1
calcium regulated heat stable protein 1, 24kDa
chr1_+_155006300 1.31 ENST00000295542.1
ENST00000392480.1
ENST00000423025.2
ENST00000368419.2
DC-STAMP domain containing 1
chr15_+_57998821 1.30 ENST00000299638.3
polymerase (RNA) II (DNA directed) polypeptide M
chr3_-_19975665 1.28 ENST00000295824.9
ENST00000389256.4
EF-hand domain family, member B
chr19_+_18530184 1.28 ENST00000601357.2
single stranded DNA binding protein 4
chr11_+_844406 1.27 ENST00000397404.1
tetraspanin 4
chr3_-_145940214 1.24 ENST00000481701.1
phospholipid scramblase 4
chr9_-_134151915 1.24 ENST00000372271.3
family with sequence similarity 78, member A
chr6_+_31730773 1.23 ENST00000415669.2
ENST00000425424.1
suppressor APC domain containing 1
chr22_-_50699701 1.23 ENST00000395780.1
mitogen-activated protein kinase 12
chr8_-_95274536 1.23 ENST00000297596.2
ENST00000396194.2
GTP binding protein overexpressed in skeletal muscle
chr1_+_66820058 1.22 ENST00000480109.2
phosphodiesterase 4B, cAMP-specific
chr3_+_160117087 1.22 ENST00000357388.3
structural maintenance of chromosomes 4
chr1_+_45212074 1.21 ENST00000372217.1
kinesin family member 2C
chr8_+_26371763 1.20 ENST00000521913.1
dihydropyrimidinase-like 2
chr17_-_53046058 1.20 ENST00000571584.1
ENST00000299335.3
cytochrome c oxidase assembly homolog 11 (yeast)
chr6_+_151561085 1.20 ENST00000402676.2
A kinase (PRKA) anchor protein 12
chr7_+_76026832 1.20 ENST00000336517.4
zona pellucida glycoprotein 3 (sperm receptor)
chr12_+_52056548 1.18 ENST00000545061.1
ENST00000355133.3
sodium channel, voltage gated, type VIII, alpha subunit
chr19_-_41220957 1.18 ENST00000596357.1
ENST00000243583.6
ENST00000600080.1
ENST00000595254.1
ENST00000601967.1
aarF domain containing kinase 4
chr2_+_169659121 1.17 ENST00000397206.2
ENST00000397209.2
ENST00000421711.2
nitric oxide synthase trafficking
chr10_+_95848824 1.17 ENST00000371385.3
ENST00000371375.1
phospholipase C, epsilon 1
chr16_-_57514277 1.17 ENST00000562008.1
ENST00000567214.1
docking protein 4
chr2_+_101591314 1.17 ENST00000450763.1
neuronal PAS domain protein 2
chr15_-_56209306 1.14 ENST00000506154.1
ENST00000338963.2
ENST00000508342.1
neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
chr3_+_136537911 1.14 ENST00000393079.3
solute carrier family 35, member G2
chr20_-_25320367 1.14 ENST00000450393.1
ENST00000491682.1
abhydrolase domain containing 12
chr2_+_175352114 1.14 ENST00000444196.1
ENST00000417038.1
ENST00000606406.1
AC010894.3
chr2_+_169658928 1.13 ENST00000317647.7
ENST00000445023.2
nitric oxide synthase trafficking
chr16_+_2198604 1.13 ENST00000210187.6
RAB26, member RAS oncogene family
chr8_+_27629459 1.12 ENST00000523566.1
establishment of sister chromatid cohesion N-acetyltransferase 2
chrX_-_70473957 1.11 ENST00000373984.3
ENST00000314425.5
ENST00000373982.1
zinc finger, MYM-type 3
chr4_+_129349188 1.11 ENST00000511497.1
RP11-420A23.1
chr14_+_24779376 1.11 ENST00000530080.1
leukotriene B4 receptor 2
chr11_+_65657875 1.11 ENST00000312579.2
coiled-coil domain containing 85B
chr2_-_25100893 1.11 ENST00000433852.1
adenylate cyclase 3
chr3_+_136537816 1.11 ENST00000446465.2
solute carrier family 35, member G2
chr14_+_100240019 1.11 ENST00000556199.1
echinoderm microtubule associated protein like 1
chr19_-_10613862 1.09 ENST00000592055.1
kelch-like ECH-associated protein 1
chr1_+_45212051 1.09 ENST00000372222.3
kinesin family member 2C
chrX_+_129473859 1.09 ENST00000424447.1
solute carrier family 25 (mitochondrial carrier, brain), member 14
chr7_-_100881109 1.08 ENST00000308344.5
claudin 15
chr3_-_52864680 1.07 ENST00000406595.1
ENST00000485816.1
ENST00000434759.3
ENST00000346281.5
ENST00000266041.4
inter-alpha-trypsin inhibitor heavy chain family, member 4
chr16_-_29874211 1.07 ENST00000563415.1
CDP-diacylglycerol--inositol 3-phosphatidyltransferase
chr22_-_50970919 1.06 ENST00000329363.4
ENST00000437588.1
outer dense fiber of sperm tails 3B
chr14_-_81408093 1.06 ENST00000555265.1
centrosomal protein 128kDa
chr3_-_137851220 1.06 ENST00000236709.3
alpha-1,4-N-acetylglucosaminyltransferase

Network of associatons between targets according to the STRING database.

First level regulatory network of STAT1_STAT3_BCL6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
5.6 16.8 GO:2000502 negative regulation of natural killer cell chemotaxis(GO:2000502)
4.2 33.4 GO:1902998 regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
2.7 10.7 GO:0019056 modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
1.6 10.9 GO:0038123 toll-like receptor TLR1:TLR2 signaling pathway(GO:0038123) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
1.4 19.6 GO:0043152 induction of bacterial agglutination(GO:0043152)
1.1 5.4 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
1.0 3.1 GO:1900738 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
1.0 3.1 GO:0007412 axon target recognition(GO:0007412)
1.0 3.0 GO:1903410 lysine import(GO:0034226) L-lysine import(GO:0061461) L-lysine import into cell(GO:1903410)
1.0 5.8 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
1.0 2.9 GO:0051685 maintenance of ER location(GO:0051685)
0.9 2.6 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.8 6.4 GO:2000860 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.7 2.2 GO:1902824 positive regulation of late endosome to lysosome transport(GO:1902824)
0.7 3.3 GO:2001180 negative regulation of interleukin-10 secretion(GO:2001180) negative regulation of interleukin-12 secretion(GO:2001183)
0.6 1.9 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.6 1.8 GO:0071140 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
0.6 2.4 GO:0097069 cellular response to thyroxine stimulus(GO:0097069) cellular response to L-phenylalanine derivative(GO:1904387)
0.6 3.5 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.6 17.4 GO:0021516 dorsal spinal cord development(GO:0021516)
0.6 1.7 GO:0006154 adenosine catabolic process(GO:0006154) inosine biosynthetic process(GO:0046103)
0.6 2.2 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.6 8.9 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.5 2.0 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.5 2.9 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.5 1.8 GO:0034499 late endosome to Golgi transport(GO:0034499)
0.5 0.9 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.4 1.2 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.4 1.2 GO:2000196 positive regulation of female gonad development(GO:2000196)
0.4 8.6 GO:0002115 store-operated calcium entry(GO:0002115)
0.4 1.8 GO:1904835 vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.4 6.0 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.4 3.2 GO:0089700 protein kinase D signaling(GO:0089700)
0.3 2.1 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.3 3.3 GO:2001300 lipoxin metabolic process(GO:2001300)
0.3 1.3 GO:0001188 RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
0.3 6.1 GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030949) smooth muscle cell-matrix adhesion(GO:0061302)
0.3 1.6 GO:0015862 uridine transport(GO:0015862)
0.3 0.3 GO:0014839 myoblast migration involved in skeletal muscle regeneration(GO:0014839)
0.3 1.5 GO:0052056 modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
0.3 3.7 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.3 2.6 GO:0006572 tyrosine catabolic process(GO:0006572)
0.3 2.9 GO:0014827 intestine smooth muscle contraction(GO:0014827)
0.3 1.1 GO:0052651 monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.3 3.1 GO:0019344 cysteine biosynthetic process(GO:0019344)
0.3 0.8 GO:0006624 vacuolar protein processing(GO:0006624)
0.3 0.8 GO:0097032 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.3 1.1 GO:0008355 olfactory learning(GO:0008355)
0.3 1.1 GO:0090289 regulation of osteoclast proliferation(GO:0090289)
0.3 0.5 GO:1903413 cellular response to bile acid(GO:1903413)
0.3 1.8 GO:0060356 leucine import(GO:0060356)
0.3 1.0 GO:0098968 neurotransmitter receptor transport postsynaptic membrane to endosome(GO:0098968)
0.3 0.8 GO:0032203 telomere formation via telomerase(GO:0032203)
0.2 1.0 GO:0097068 response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
0.2 0.7 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.2 4.6 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.2 2.4 GO:0045959 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959)
0.2 1.8 GO:0009253 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.2 0.9 GO:0006669 sphinganine-1-phosphate biosynthetic process(GO:0006669)
0.2 1.6 GO:0046125 thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.2 2.2 GO:0045627 positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.2 1.1 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.2 0.7 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.2 0.9 GO:0046967 cytosol to ER transport(GO:0046967)
0.2 3.9 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.2 4.4 GO:0045779 negative regulation of bone resorption(GO:0045779)
0.2 2.5 GO:0035754 B cell chemotaxis(GO:0035754)
0.2 0.8 GO:1902161 positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)
0.2 1.0 GO:0060024 rhythmic synaptic transmission(GO:0060024) positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.2 1.8 GO:0021840 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.2 3.2 GO:0030321 transepithelial chloride transport(GO:0030321)
0.2 0.6 GO:0006174 dADP phosphorylation(GO:0006174) dGDP phosphorylation(GO:0006186) AMP phosphorylation(GO:0006756) CDP phosphorylation(GO:0061508) dAMP phosphorylation(GO:0061565) CMP phosphorylation(GO:0061566) dCMP phosphorylation(GO:0061567) GDP phosphorylation(GO:0061568) UDP phosphorylation(GO:0061569) dCDP phosphorylation(GO:0061570) TDP phosphorylation(GO:0061571)
0.2 2.4 GO:0035095 behavioral response to nicotine(GO:0035095)
0.2 0.6 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.2 1.2 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.2 0.6 GO:1990697 protein depalmitoleylation(GO:1990697)
0.2 0.6 GO:0002728 negative regulation of natural killer cell cytokine production(GO:0002728)
0.2 2.3 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.2 0.4 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
0.2 3.2 GO:0090331 negative regulation of platelet aggregation(GO:0090331)
0.2 0.6 GO:0060254 regulation of N-terminal protein palmitoylation(GO:0060254) negative regulation of N-terminal protein palmitoylation(GO:0060262) negative regulation of protein lipidation(GO:1903060)
0.2 1.1 GO:0034421 post-translational protein acetylation(GO:0034421)
0.2 0.6 GO:0043318 negative regulation of dendritic cell antigen processing and presentation(GO:0002605) regulation of cytotoxic T cell degranulation(GO:0043317) negative regulation of cytotoxic T cell degranulation(GO:0043318)
0.2 0.7 GO:0046035 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.2 0.9 GO:0003095 pressure natriuresis(GO:0003095) vitamin E metabolic process(GO:0042360)
0.2 1.8 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.2 1.0 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.2 0.7 GO:0050928 negative regulation of positive chemotaxis(GO:0050928)
0.2 1.0 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.2 0.2 GO:0006844 acyl carnitine transport(GO:0006844) acyl carnitine transmembrane transport(GO:1902616)
0.2 0.7 GO:0035701 hematopoietic stem cell migration(GO:0035701)
0.2 0.5 GO:1901253 negative regulation of intracellular transport of viral material(GO:1901253)
0.2 0.6 GO:2000569 T-helper 2 cell activation(GO:0035712) regulation of T-helper 2 cell activation(GO:2000569) positive regulation of T-helper 2 cell activation(GO:2000570)
0.2 0.3 GO:0035262 gonad morphogenesis(GO:0035262)
0.2 0.8 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.2 3.0 GO:0051601 exocyst localization(GO:0051601)
0.2 1.1 GO:0050680 negative regulation of epithelial cell proliferation(GO:0050680)
0.1 1.5 GO:0045218 zonula adherens maintenance(GO:0045218)
0.1 0.3 GO:0001922 B-1 B cell homeostasis(GO:0001922)
0.1 0.9 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 0.7 GO:0009213 pyrimidine nucleoside triphosphate catabolic process(GO:0009149) pyrimidine deoxyribonucleoside triphosphate catabolic process(GO:0009213)
0.1 1.1 GO:0010767 regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage(GO:0010767)
0.1 0.4 GO:0030070 insulin processing(GO:0030070)
0.1 2.5 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.1 2.3 GO:0035372 protein localization to microtubule(GO:0035372)
0.1 0.5 GO:0035669 TRAM-dependent toll-like receptor signaling pathway(GO:0035668) TRAM-dependent toll-like receptor 4 signaling pathway(GO:0035669)
0.1 0.5 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.1 0.5 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
0.1 0.7 GO:0019303 D-ribose catabolic process(GO:0019303)
0.1 5.7 GO:0010506 regulation of autophagy(GO:0010506)
0.1 0.8 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.1 0.9 GO:0097473 cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.1 0.9 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.1 0.4 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.1 0.2 GO:0021530 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.1 1.7 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.1 0.7 GO:0060295 regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.1 0.8 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.1 2.0 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.1 0.8 GO:0060480 lung goblet cell differentiation(GO:0060480)
0.1 2.8 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.1 0.5 GO:0002309 T cell proliferation involved in immune response(GO:0002309)
0.1 3.4 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.1 0.4 GO:1990022 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.1 2.1 GO:0051775 response to redox state(GO:0051775)
0.1 1.2 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.1 0.9 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.1 0.8 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.1 0.4 GO:0044211 CTP salvage(GO:0044211)
0.1 0.7 GO:0055129 L-proline biosynthetic process(GO:0055129)
0.1 1.0 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.1 0.7 GO:0070091 glucagon secretion(GO:0070091) regulation of glucagon secretion(GO:0070092)
0.1 10.7 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.1 2.1 GO:0017121 phospholipid scrambling(GO:0017121)
0.1 0.5 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.1 0.5 GO:1903826 arginine transmembrane transport(GO:1903826)
0.1 0.2 GO:0046968 peptide antigen transport(GO:0046968)
0.1 0.5 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.1 0.8 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.1 0.6 GO:2000852 corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)
0.1 0.6 GO:1902896 terminal web assembly(GO:1902896)
0.1 0.1 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.1 0.5 GO:0002727 natural killer cell cytokine production(GO:0002370) regulation of natural killer cell cytokine production(GO:0002727) positive regulation of natural killer cell cytokine production(GO:0002729)
0.1 0.5 GO:0000255 allantoin metabolic process(GO:0000255)
0.1 0.8 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.1 2.8 GO:0070207 protein homotrimerization(GO:0070207)
0.1 1.2 GO:1901078 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 1.5 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 2.0 GO:0048266 behavioral response to pain(GO:0048266)
0.1 0.4 GO:0014028 mesoderm migration involved in gastrulation(GO:0007509) notochord formation(GO:0014028)
0.1 1.0 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 0.5 GO:0060620 regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.1 0.4 GO:0045337 geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384) farnesyl diphosphate biosynthetic process(GO:0045337)
0.1 2.5 GO:0045332 phospholipid translocation(GO:0045332)
0.1 0.5 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.1 0.6 GO:0050482 arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.1 0.7 GO:0070560 protein secretion by platelet(GO:0070560)
0.1 0.4 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.1 1.0 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.1 0.5 GO:0019075 virus maturation(GO:0019075)
0.1 0.4 GO:0032264 IMP salvage(GO:0032264)
0.1 0.8 GO:0006013 mannose metabolic process(GO:0006013)
0.1 1.2 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.1 0.3 GO:0071400 cellular response to oleic acid(GO:0071400)
0.1 0.5 GO:0032696 negative regulation of interleukin-13 production(GO:0032696)
0.1 2.4 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.1 0.2 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.1 0.6 GO:1900121 negative regulation of receptor binding(GO:1900121)
0.1 0.4 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.1 4.3 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.1 1.6 GO:0035455 response to interferon-alpha(GO:0035455)
0.1 0.7 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.1 6.4 GO:0006521 regulation of cellular amino acid metabolic process(GO:0006521)
0.1 3.9 GO:0060612 adipose tissue development(GO:0060612)
0.1 1.4 GO:0003334 keratinocyte development(GO:0003334)
0.1 0.3 GO:0036309 protein localization to M-band(GO:0036309)
0.1 3.0 GO:0042073 intraciliary transport(GO:0042073)
0.1 0.2 GO:0006286 base-excision repair, base-free sugar-phosphate removal(GO:0006286)
0.1 1.8 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1 1.1 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.1 1.0 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.1 0.9 GO:0045723 positive regulation of fatty acid biosynthetic process(GO:0045723)
0.1 0.8 GO:0006089 lactate metabolic process(GO:0006089)
0.1 0.6 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0 0.5 GO:0051454 pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.0 0.2 GO:0060390 regulation of SMAD protein import into nucleus(GO:0060390) positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0 0.5 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 1.0 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.0 0.2 GO:0016094 polyprenol biosynthetic process(GO:0016094)
0.0 0.4 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.2 GO:0031642 negative regulation of myelination(GO:0031642)
0.0 0.6 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.1 GO:0006447 regulation of translational initiation by iron(GO:0006447)
0.0 0.5 GO:0042420 dopamine catabolic process(GO:0042420)
0.0 2.8 GO:0061718 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0 0.9 GO:0051023 regulation of immunoglobulin secretion(GO:0051023)
0.0 2.3 GO:0050855 regulation of B cell receptor signaling pathway(GO:0050855)
0.0 1.4 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 0.2 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.0 0.5 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 1.0 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.0 1.5 GO:0043555 regulation of translation in response to stress(GO:0043555)
0.0 1.5 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.8 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.0 3.7 GO:0009060 aerobic respiration(GO:0009060)
0.0 0.4 GO:1901978 positive regulation of cell cycle checkpoint(GO:1901978)
0.0 0.4 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.2 GO:0071348 cellular response to interleukin-11(GO:0071348)
0.0 0.5 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.3 GO:0033690 positive regulation of osteoblast proliferation(GO:0033690)
0.0 1.1 GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261)
0.0 0.3 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.0 0.7 GO:2000121 regulation of removal of superoxide radicals(GO:2000121)
0.0 2.3 GO:0050999 regulation of nitric-oxide synthase activity(GO:0050999)
0.0 0.4 GO:0070836 caveola assembly(GO:0070836)
0.0 0.5 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.0 0.8 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 0.5 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.2 GO:0099538 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551)
0.0 0.2 GO:0071504 cellular response to heparin(GO:0071504)
0.0 0.5 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.1 GO:0021562 vestibulocochlear nerve development(GO:0021562)
0.0 1.0 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.7 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 1.9 GO:0015949 nucleobase-containing small molecule interconversion(GO:0015949)
0.0 0.5 GO:0031643 positive regulation of myelination(GO:0031643)
0.0 0.4 GO:0016198 axon choice point recognition(GO:0016198)
0.0 0.6 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.3 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.5 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.0 0.1 GO:0033274 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.0 2.4 GO:0042733 embryonic digit morphogenesis(GO:0042733)
0.0 1.2 GO:2001222 regulation of neuron migration(GO:2001222)
0.0 0.5 GO:0071361 cellular response to ethanol(GO:0071361)
0.0 1.0 GO:0061641 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 1.6 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.0 0.1 GO:1902869 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) regulation of amacrine cell differentiation(GO:1902869) positive regulation of amacrine cell differentiation(GO:1902871)
0.0 0.4 GO:0022010 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.0 1.1 GO:0006953 acute-phase response(GO:0006953)
0.0 0.3 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 1.3 GO:0070527 platelet aggregation(GO:0070527)
0.0 0.3 GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.0 1.1 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.7 GO:0047497 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.0 0.2 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
0.0 0.2 GO:0097338 response to clozapine(GO:0097338)
0.0 3.1 GO:0031638 zymogen activation(GO:0031638)
0.0 0.4 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 1.9 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 0.1 GO:1990654 sebum secreting cell proliferation(GO:1990654)
0.0 0.1 GO:0015722 canalicular bile acid transport(GO:0015722) pyrimidine nucleobase transport(GO:0015855) purine nucleobase transmembrane transport(GO:1904823)
0.0 0.1 GO:0055096 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096)
0.0 0.5 GO:1904778 protein localization to cell cortex(GO:0072697) regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 0.2 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.1 GO:0035494 SNARE complex disassembly(GO:0035494)
0.0 0.4 GO:0010447 response to acidic pH(GO:0010447)
0.0 0.2 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.0 0.3 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.2 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.0 GO:0007538 primary sex determination(GO:0007538)
0.0 0.2 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.5 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 0.1 GO:0002304 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.0 0.1 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.0 0.5 GO:0034035 purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.0 0.5 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.0 0.4 GO:0007098 centrosome cycle(GO:0007098)
0.0 0.2 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.0 0.0 GO:0071456 cellular response to hypoxia(GO:0071456)
0.0 1.2 GO:0030516 regulation of axon extension(GO:0030516)
0.0 0.1 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0 0.3 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.0 0.5 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.6 GO:1902808 positive regulation of cell cycle G1/S phase transition(GO:1902808)
0.0 0.5 GO:0060271 cilium morphogenesis(GO:0060271)
0.0 0.3 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.2 GO:0007588 excretion(GO:0007588)
0.0 0.2 GO:0002548 monocyte chemotaxis(GO:0002548)
0.0 0.1 GO:0018343 protein farnesylation(GO:0018343)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 33.3 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
1.6 22.8 GO:0005577 fibrinogen complex(GO:0005577)
1.5 6.1 GO:0071062 rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062)
1.2 10.9 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.9 2.6 GO:0005588 collagen type V trimer(GO:0005588)
0.6 2.4 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.5 3.9 GO:1990111 spermatoproteasome complex(GO:1990111)
0.4 1.3 GO:0005668 RNA polymerase transcription factor SL1 complex(GO:0005668)
0.4 1.1 GO:0071821 FANCM-MHF complex(GO:0071821)
0.3 1.4 GO:0005873 plus-end kinesin complex(GO:0005873)
0.3 2.6 GO:0005579 membrane attack complex(GO:0005579)
0.3 1.2 GO:0002081 outer acrosomal membrane(GO:0002081)
0.3 2.1 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.3 2.6 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.3 3.7 GO:0000796 condensin complex(GO:0000796)
0.2 1.4 GO:0008537 proteasome activator complex(GO:0008537)
0.2 4.2 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.2 6.4 GO:0043194 axon initial segment(GO:0043194)
0.2 4.6 GO:0005915 zonula adherens(GO:0005915)
0.2 0.5 GO:0032002 interleukin-28 receptor complex(GO:0032002)
0.2 3.6 GO:0036038 MKS complex(GO:0036038)
0.2 2.0 GO:0030991 intraciliary transport particle A(GO:0030991)
0.2 30.1 GO:0072562 blood microparticle(GO:0072562)
0.1 0.8 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.1 1.8 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 1.0 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.1 0.9 GO:0042825 TAP complex(GO:0042825)
0.1 0.5 GO:0031251 PAN complex(GO:0031251)
0.1 0.4 GO:0044609 DBIRD complex(GO:0044609)
0.1 0.8 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.1 1.9 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.1 0.7 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.1 1.9 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 2.4 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 0.4 GO:1902912 pyruvate kinase complex(GO:1902912)
0.1 1.3 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.1 0.8 GO:0031429 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.1 0.6 GO:1990357 terminal web(GO:1990357)
0.1 0.7 GO:0036128 CatSper complex(GO:0036128)
0.1 1.1 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.1 1.1 GO:1990023 mitotic spindle midzone(GO:1990023)
0.1 0.8 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
0.1 0.7 GO:0071953 elastic fiber(GO:0071953)
0.1 2.3 GO:0031083 BLOC-1 complex(GO:0031083)
0.1 1.5 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.1 0.6 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 0.2 GO:0098855 HCN channel complex(GO:0098855)
0.1 3.0 GO:0000421 autophagosome membrane(GO:0000421)
0.1 1.0 GO:0042555 MCM complex(GO:0042555)
0.0 1.8 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 1.6 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.2 GO:0016938 kinesin I complex(GO:0016938)
0.0 1.5 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.6 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 6.6 GO:0005581 collagen trimer(GO:0005581)
0.0 1.2 GO:0051233 spindle midzone(GO:0051233)
0.0 4.6 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 1.5 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.8 GO:0032059 bleb(GO:0032059)
0.0 0.2 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.0 0.4 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
0.0 0.5 GO:0008091 spectrin(GO:0008091)
0.0 0.5 GO:0033269 internode region of axon(GO:0033269)
0.0 1.1 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 0.7 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 1.1 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 1.3 GO:0030673 axolemma(GO:0030673)
0.0 0.7 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.4 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.8 GO:0031045 dense core granule(GO:0031045)
0.0 0.5 GO:0000813 ESCRT I complex(GO:0000813)
0.0 3.1 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 1.2 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.3 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.5 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.5 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.5 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 1.4 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.2 GO:0000243 commitment complex(GO:0000243)
0.0 2.4 GO:0044215 other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.0 9.1 GO:0043235 receptor complex(GO:0043235)
0.0 0.9 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.5 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.7 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.3 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.1 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.2 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.2 GO:0097433 dense body(GO:0097433)
0.0 0.5 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.2 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.4 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.8 GO:1904115 axon cytoplasm(GO:1904115)
0.0 0.1 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.0 5.9 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 1.1 GO:0005643 nuclear pore(GO:0005643)
0.0 0.0 GO:1990015 mesaxon(GO:0097453) ensheathing process(GO:1990015)
0.0 0.4 GO:0043679 axon terminus(GO:0043679)
0.0 1.3 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.8 GO:0005813 centrosome(GO:0005813)
0.0 0.6 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.3 GO:0043204 perikaryon(GO:0043204)
0.0 0.9 GO:0043198 dendritic shaft(GO:0043198)
0.0 2.5 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 8.1 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 0.4 GO:0000145 exocyst(GO:0000145)
0.0 0.1 GO:0001652 granular component(GO:0001652)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 11.2 GO:0016019 peptidoglycan receptor activity(GO:0016019)
1.4 4.2 GO:0050135 NAD(P)+ nucleosidase activity(GO:0050135)
1.0 33.4 GO:0051787 misfolded protein binding(GO:0051787)
0.9 2.8 GO:0003881 CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity(GO:0003881)
0.9 10.8 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.8 3.3 GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.8 3.1 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.7 11.0 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.7 2.2 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
0.7 4.6 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.6 5.8 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.6 2.4 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.6 19.1 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.5 3.9 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.5 8.6 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.5 1.9 GO:0004362 glutathione-disulfide reductase activity(GO:0004362)
0.4 2.1 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.4 2.5 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.3 1.0 GO:0043337 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572) CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity(GO:0043337)
0.3 3.2 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.3 1.6 GO:0004905 type I interferon receptor activity(GO:0004905)
0.3 8.6 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.3 3.2 GO:0008158 hedgehog receptor activity(GO:0008158)
0.3 2.5 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.3 0.9 GO:0005174 CD40 receptor binding(GO:0005174)
0.3 2.6 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.3 2.9 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.3 1.1 GO:0001632 leukotriene B4 receptor activity(GO:0001632)
0.3 1.6 GO:0004797 thymidine kinase activity(GO:0004797)
0.3 2.1 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.3 0.8 GO:0017116 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116)
0.2 1.2 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.2 4.5 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.2 0.7 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.2 1.5 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.2 6.3 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.2 2.3 GO:0019237 centromeric DNA binding(GO:0019237)
0.2 3.1 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.2 0.8 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.2 0.6 GO:0019781 NEDD8 activating enzyme activity(GO:0019781)
0.2 0.6 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.2 0.6 GO:1990699 palmitoleyl hydrolase activity(GO:1990699)
0.2 0.9 GO:0018685 alkane 1-monooxygenase activity(GO:0018685)
0.2 3.1 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.2 0.2 GO:0015227 acyl carnitine transmembrane transporter activity(GO:0015227)
0.2 1.4 GO:0061133 endopeptidase activator activity(GO:0061133)
0.2 4.9 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.2 1.8 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.2 3.0 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.2 1.8 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.1 1.1 GO:0050815 phosphoserine binding(GO:0050815)
0.1 1.1 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.1 1.5 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.1 1.9 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.1 1.6 GO:0097322 7SK snRNA binding(GO:0097322)
0.1 1.3 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 0.9 GO:0046979 TAP2 binding(GO:0046979)
0.1 0.7 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.1 1.4 GO:0003796 lysozyme activity(GO:0003796)
0.1 1.7 GO:0004000 adenosine deaminase activity(GO:0004000)
0.1 2.0 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 1.5 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.1 0.7 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.1 0.6 GO:0019770 IgG receptor activity(GO:0019770)
0.1 2.4 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 1.2 GO:0032190 acrosin binding(GO:0032190)
0.1 3.0 GO:0017049 GTP-Rho binding(GO:0017049)
0.1 2.7 GO:0004065 arylsulfatase activity(GO:0004065)
0.1 1.1 GO:0004849 uridine kinase activity(GO:0004849)
0.1 3.2 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.1 2.1 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.1 2.1 GO:0005522 profilin binding(GO:0005522)
0.1 1.8 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 0.6 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
0.1 3.0 GO:0004697 protein kinase C activity(GO:0004697)
0.1 0.5 GO:0047685 amine sulfotransferase activity(GO:0047685)
0.1 0.7 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.1 2.5 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 0.8 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.1 0.8 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.1 0.9 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.1 0.4 GO:0004161 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.1 0.6 GO:0050145 nucleoside phosphate kinase activity(GO:0050145)
0.1 3.3 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 1.5 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 0.7 GO:0032552 deoxyribonucleotide binding(GO:0032552)
0.1 0.2 GO:0008193 tRNA guanylyltransferase activity(GO:0008193)
0.1 0.3 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.1 0.2 GO:0042007 interleukin-18 binding(GO:0042007)
0.1 2.6 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.1 0.5 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.1 1.0 GO:0033038 bitter taste receptor activity(GO:0033038)
0.1 1.3 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 0.5 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.1 0.2 GO:0001601 peptide YY receptor activity(GO:0001601)
0.1 0.4 GO:0043208 fucose binding(GO:0042806) glycosphingolipid binding(GO:0043208)
0.1 0.4 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 0.2 GO:0043813 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812) phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813)
0.1 1.9 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 0.8 GO:0052658 inositol-polyphosphate 5-phosphatase activity(GO:0004445) inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.1 1.6 GO:0004383 guanylate cyclase activity(GO:0004383)
0.1 0.1 GO:0005345 purine nucleobase transmembrane transporter activity(GO:0005345) pyrimidine nucleobase transmembrane transporter activity(GO:0005350)
0.1 0.2 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
0.0 1.5 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.2 GO:0002094 polyprenyltransferase activity(GO:0002094)
0.0 1.3 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.0 2.8 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.0 1.9 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.5 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 1.6 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 2.6 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 1.9 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 1.4 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 2.0 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 1.2 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.8 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 2.8 GO:0019894 kinesin binding(GO:0019894)
0.0 0.9 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.5 GO:0042731 PH domain binding(GO:0042731)
0.0 0.3 GO:0004515 nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0 0.2 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.8 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.0 0.8 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.1 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.5 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 1.2 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.1 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.0 4.6 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.5 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.3 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.0 0.2 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.0 0.1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.7 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.6 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.1 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.0 0.1 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.0 0.5 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 3.5 GO:0051087 chaperone binding(GO:0051087)
0.0 0.5 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 3.7 GO:0030165 PDZ domain binding(GO:0030165)
0.0 1.0 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.2 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.5 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.2 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 1.8 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.5 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 1.3 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.4 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.3 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.2 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.2 GO:1990932 5.8S rRNA binding(GO:1990932)
0.0 0.1 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.0 0.4 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.7 GO:0030507 spectrin binding(GO:0030507)
0.0 0.4 GO:0031432 titin binding(GO:0031432)
0.0 0.1 GO:0017057 6-phosphogluconolactonase activity(GO:0017057)
0.0 5.7 GO:0030674 protein binding, bridging(GO:0030674)
0.0 0.2 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.3 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.5 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.0 GO:0017098 sulfonylurea receptor binding(GO:0017098)
0.0 0.2 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.1 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.0 2.7 GO:0046332 SMAD binding(GO:0046332)
0.0 0.5 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.2 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.9 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.2 GO:0047760 butyrate-CoA ligase activity(GO:0047760)
0.0 1.4 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.1 GO:0005113 patched binding(GO:0005113)
0.0 0.3 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.3 GO:0004707 MAP kinase activity(GO:0004707)
0.0 2.8 GO:0000149 SNARE binding(GO:0000149)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 1.1 GO:0019003 GDP binding(GO:0019003)
0.0 1.0 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.4 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.4 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 2.4 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.7 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.3 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.2 GO:0005537 mannose binding(GO:0005537)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 22.2 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.3 22.1 PID IL23 PATHWAY IL23-mediated signaling events
0.2 2.7 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.2 29.7 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.2 6.1 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 3.1 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.1 6.3 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 2.1 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.1 8.6 PID SHP2 PATHWAY SHP2 signaling
0.1 1.2 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.1 1.8 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.1 6.3 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.1 8.5 PID AURORA B PATHWAY Aurora B signaling
0.1 4.0 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.1 11.8 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.1 5.5 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.1 2.6 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.1 4.5 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 1.6 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 5.6 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.1 3.2 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.1 1.6 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 2.0 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 1.2 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 3.0 ST GA13 PATHWAY G alpha 13 Pathway
0.1 2.2 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 1.3 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 2.3 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 2.6 NABA COLLAGENS Genes encoding collagen proteins
0.0 1.1 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 2.4 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.2 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.8 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.7 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.7 PID RHOA PATHWAY RhoA signaling pathway
0.0 1.9 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.5 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.5 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.6 PID BCR 5PATHWAY BCR signaling pathway
0.0 1.1 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 1.0 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.2 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 1.6 PID E2F PATHWAY E2F transcription factor network
0.0 0.4 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.8 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.3 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 3.9 NABA SECRETED FACTORS Genes encoding secreted soluble factors

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 31.9 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.5 8.6 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.4 17.3 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.4 6.9 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.3 5.8 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.3 5.4 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.3 2.9 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.2 10.9 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.2 2.5 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.2 2.4 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1 3.2 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 3.9 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.1 7.0 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 2.7 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 1.8 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 21.8 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 1.5 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.1 8.8 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.1 1.9 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 1.6 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.1 3.9 REACTOME KINESINS Genes involved in Kinesins
0.1 3.7 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 2.7 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 1.6 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.1 2.3 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.1 3.1 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 1.7 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 1.1 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.1 2.1 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.1 3.0 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 0.5 REACTOME OPSINS Genes involved in Opsins
0.1 2.3 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.1 1.0 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.1 2.6 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 1.6 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.7 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 2.3 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 1.2 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 1.9 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.6 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 3.4 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 2.5 REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS Genes involved in Post NMDA receptor activation events
0.0 1.0 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.9 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 6.8 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 2.6 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 1.1 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.5 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 1.4 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 1.0 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 2.3 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 1.2 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.4 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 1.5 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.3 REACTOME CA DEPENDENT EVENTS Genes involved in Ca-dependent events
0.0 0.8 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 0.7 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.7 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 2.2 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.8 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 0.6 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.1 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.4 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.8 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.8 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.7 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.9 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.9 REACTOME CHROMOSOME MAINTENANCE Genes involved in Chromosome Maintenance
0.0 2.0 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.0 0.4 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 2.1 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.8 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 1.2 REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE Genes involved in Cell death signalling via NRAGE, NRIF and NADE