Project
SARS-CoV-2 Analysis Results (GEO series: GSE147507)
Navigation
Downloads
Results for STAT4
Z-value: 0.96
Motif logo
Transcription factors associated with STAT4
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| STAT4 | hg19_v2_chr2_-_192016316_192016325 | 0.61 | 4.4e-03 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of STAT4
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 11.3 | GO:0060512 | prostate gland morphogenesis(GO:0060512) |
| 0.0 | 8.1 | GO:1900181 | negative regulation of protein localization to nucleus(GO:1900181) |
| 0.4 | 3.7 | GO:2000660 | negative regulation of interleukin-1-mediated signaling pathway(GO:2000660) |
| 0.6 | 3.4 | GO:0033591 | response to L-ascorbic acid(GO:0033591) |
| 0.1 | 2.7 | GO:0006607 | NLS-bearing protein import into nucleus(GO:0006607) |
| 0.2 | 2.6 | GO:0008090 | retrograde axonal transport(GO:0008090) |
| 0.4 | 2.5 | GO:0060574 | intestinal epithelial cell maturation(GO:0060574) |
| 0.2 | 2.5 | GO:0018026 | peptidyl-lysine monomethylation(GO:0018026) |
| 0.1 | 2.4 | GO:0046339 | diacylglycerol metabolic process(GO:0046339) |
| 0.7 | 2.1 | GO:0060278 | regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 10.2 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
| 0.1 | 3.4 | GO:0071682 | endocytic vesicle lumen(GO:0071682) |
| 0.0 | 2.9 | GO:0001650 | fibrillar center(GO:0001650) |
| 0.4 | 2.6 | GO:0031673 | H zone(GO:0031673) |
| 0.8 | 2.5 | GO:0070557 | PCNA-p21 complex(GO:0070557) |
| 0.7 | 2.1 | GO:0043511 | inhibin complex(GO:0043511) inhibin A complex(GO:0043512) |
| 0.1 | 2.1 | GO:0043203 | axon hillock(GO:0043203) |
| 0.2 | 1.9 | GO:0097442 | CA3 pyramidal cell dendrite(GO:0097442) |
| 0.1 | 1.2 | GO:0033263 | CORVET complex(GO:0033263) |
| 0.0 | 1.2 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 11.3 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.2 | 10.4 | GO:0098641 | cadherin binding involved in cell-cell adhesion(GO:0098641) |
| 0.1 | 5.9 | GO:0051019 | mitogen-activated protein kinase binding(GO:0051019) |
| 1.2 | 3.7 | GO:0005150 | interleukin-1, Type I receptor binding(GO:0005150) |
| 0.0 | 3.7 | GO:0050840 | extracellular matrix binding(GO:0050840) |
| 0.1 | 2.6 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
| 0.8 | 2.5 | GO:0019912 | cyclin-dependent protein kinase activating kinase activity(GO:0019912) |
| 0.0 | 2.5 | GO:0018024 | histone-lysine N-methyltransferase activity(GO:0018024) |
| 0.1 | 2.4 | GO:0004143 | diacylglycerol kinase activity(GO:0004143) |
| 0.0 | 2.3 | GO:0050681 | androgen receptor binding(GO:0050681) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 17.2 | PID TAP63 PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 0.1 | 4.4 | PID IL1 PATHWAY | IL1-mediated signaling events |
| 0.0 | 3.9 | PID NFAT TFPATHWAY | Calcineurin-regulated NFAT-dependent transcription in lymphocytes |
| 0.0 | 3.0 | PID TCR PATHWAY | TCR signaling in naïve CD4+ T cells |
| 0.0 | 2.8 | PID P38 MK2 PATHWAY | p38 signaling mediated by MAPKAP kinases |
| 0.0 | 2.5 | PID P53 REGULATION PATHWAY | p53 pathway |
| 0.2 | 2.1 | ST JAK STAT PATHWAY | Jak-STAT Pathway |
| 0.0 | 2.1 | PID ALK1 PATHWAY | ALK1 signaling events |
| 0.0 | 1.9 | PID LKB1 PATHWAY | LKB1 signaling events |
| 0.0 | 1.6 | PID HDAC CLASSIII PATHWAY | Signaling events mediated by HDAC Class III |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 4.4 | REACTOME IL1 SIGNALING | Genes involved in Interleukin-1 signaling |
| 0.1 | 2.7 | REACTOME P38MAPK EVENTS | Genes involved in p38MAPK events |
| 0.1 | 2.7 | REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS | Genes involved in Signal regulatory protein (SIRP) family interactions |
| 0.1 | 2.5 | REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL | Genes involved in AKT phosphorylates targets in the cytosol |
| 0.2 | 2.1 | REACTOME GLYCOPROTEIN HORMONES | Genes involved in Glycoprotein hormones |
| 0.0 | 2.1 | REACTOME GROWTH HORMONE RECEPTOR SIGNALING | Genes involved in Growth hormone receptor signaling |
| 0.1 | 1.9 | REACTOME HYALURONAN METABOLISM | Genes involved in Hyaluronan metabolism |
| 0.1 | 1.9 | REACTOME MITOCHONDRIAL TRNA AMINOACYLATION | Genes involved in Mitochondrial tRNA aminoacylation |
| 0.0 | 1.8 | REACTOME EFFECTS OF PIP2 HYDROLYSIS | Genes involved in Effects of PIP2 hydrolysis |
| 0.0 | 1.6 | REACTOME PIP3 ACTIVATES AKT SIGNALING | Genes involved in PIP3 activates AKT signaling |