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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for STAT5A

Z-value: 0.59

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Transcription factors associated with STAT5A

Gene Symbol Gene ID Gene Info
STAT5A
ENSG00000126561.12 signal transducer and activator of transcription 5A

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
STAT5Ahg19_v2_chr17_+_40458130_40458188-0.321.8e-01Click!

Activity profile of STAT5A motif

Sorted Z-values of STAT5A motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr9_-_75653627 1.23 ENST00000446946.1
ALDH1A1
aldehyde dehydrogenase 1 family, member A1
chr12_-_117537240 1.10 ENST00000392545.4
ENST00000541210.1
ENST00000335209.7
TESC
tescalcin
chr12_+_20963632 1.03 ENST00000540853.1
ENST00000261196.2
SLCO1B3
solute carrier organic anion transporter family, member 1B3
chr12_+_20963647 1.02 ENST00000381545.3
SLCO1B3
solute carrier organic anion transporter family, member 1B3
chr11_-_117695449 0.98 ENST00000292079.2
FXYD2
FXYD domain containing ion transport regulator 2
chr3_+_149191723 0.96 ENST00000305354.4
TM4SF4
transmembrane 4 L six family member 4
chr3_-_148939598 0.96 ENST00000455472.3
CP
ceruloplasmin (ferroxidase)
chr9_-_123812542 0.91 ENST00000223642.1
C5
complement component 5
chr4_-_155511887 0.85 ENST00000302053.3
ENST00000403106.3
FGA
fibrinogen alpha chain
chr17_+_32582293 0.80 ENST00000580907.1
ENST00000225831.4
CCL2
chemokine (C-C motif) ligand 2
chr12_+_20968608 0.79 ENST00000381541.3
ENST00000540229.1
ENST00000553473.1
ENST00000554957.1
LST3
SLCO1B3
SLCO1B7
Putative solute carrier organic anion transporter family member 1B7; Uncharacterized protein
solute carrier organic anion transporter family, member 1B3
solute carrier organic anion transporter family, member 1B7 (non-functional)
chrY_+_15016725 0.77 ENST00000336079.3
DDX3Y
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
chr8_+_27629459 0.77 ENST00000523566.1
ESCO2
establishment of sister chromatid cohesion N-acetyltransferase 2
chr10_-_33625154 0.76 ENST00000265371.4
NRP1
neuropilin 1
chr3_-_148939835 0.75 ENST00000264613.6
CP
ceruloplasmin (ferroxidase)
chr7_-_108096822 0.75 ENST00000379028.3
ENST00000413765.2
ENST00000379022.4
NRCAM
neuronal cell adhesion molecule
chr2_-_133104839 0.75 ENST00000608279.1
RP11-725P16.2
RP11-725P16.2
chrY_+_22737604 0.71 ENST00000361365.2
EIF1AY
eukaryotic translation initiation factor 1A, Y-linked
chr7_-_95225768 0.70 ENST00000005178.5
PDK4
pyruvate dehydrogenase kinase, isozyme 4
chr8_-_27468842 0.69 ENST00000523500.1
CLU
clusterin
chr8_-_27469196 0.69 ENST00000546343.1
ENST00000560566.1
CLU
clusterin
chr17_-_26697304 0.68 ENST00000536498.1
VTN
vitronectin
chrY_+_15016013 0.67 ENST00000360160.4
ENST00000454054.1
DDX3Y
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
chr8_-_27468945 0.67 ENST00000405140.3
CLU
clusterin
chr15_+_50474385 0.66 ENST00000267842.5
SLC27A2
solute carrier family 27 (fatty acid transporter), member 2
chr8_-_27468717 0.66 ENST00000520796.1
ENST00000520491.1
CLU
clusterin
chr15_+_65843130 0.66 ENST00000569894.1
PTPLAD1
protein tyrosine phosphatase-like A domain containing 1
chr17_-_64216748 0.65 ENST00000585162.1
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr4_+_155484103 0.64 ENST00000302068.4
FGB
fibrinogen beta chain
chr19_+_35168567 0.63 ENST00000457781.2
ENST00000505163.1
ENST00000505242.1
ENST00000423823.2
ENST00000507959.1
ENST00000446502.2
ZNF302
zinc finger protein 302
chr4_-_89080003 0.63 ENST00000237612.3
ABCG2
ATP-binding cassette, sub-family G (WHITE), member 2
chr1_-_197115818 0.62 ENST00000367409.4
ENST00000294732.7
ASPM
asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
chr6_-_165989936 0.62 ENST00000354448.4
PDE10A
phosphodiesterase 10A
chr12_-_21910775 0.60 ENST00000539782.1
LDHB
lactate dehydrogenase B
chr8_-_27469383 0.60 ENST00000519742.1
CLU
clusterin
chr19_+_35168633 0.59 ENST00000505365.2
ZNF302
zinc finger protein 302
chr15_+_50474412 0.58 ENST00000380902.4
SLC27A2
solute carrier family 27 (fatty acid transporter), member 2
chr15_+_66797627 0.57 ENST00000565627.1
ENST00000564179.1
ZWILCH
zwilch kinetochore protein
chr3_-_120365866 0.57 ENST00000475447.2
HGD
homogentisate 1,2-dioxygenase
chr2_-_55237484 0.57 ENST00000394609.2
RTN4
reticulon 4
chr7_-_108096765 0.56 ENST00000379024.4
ENST00000351718.4
NRCAM
neuronal cell adhesion molecule
chr17_-_76183111 0.55 ENST00000405273.1
ENST00000590862.1
ENST00000590430.1
ENST00000586613.1
TK1
thymidine kinase 1, soluble
chrX_-_139866723 0.55 ENST00000370532.2
CDR1
cerebellar degeneration-related protein 1, 34kDa
chr17_+_6347761 0.55 ENST00000250056.8
ENST00000571373.1
ENST00000570337.2
ENST00000572595.2
ENST00000576056.1
FAM64A
family with sequence similarity 64, member A
chr10_+_30722866 0.55 ENST00000263056.1
MAP3K8
mitogen-activated protein kinase kinase kinase 8
chr3_-_13461807 0.53 ENST00000254508.5
NUP210
nucleoporin 210kDa
chr18_-_70931689 0.52 ENST00000581862.1
RP11-169F17.1
Protein LOC400655
chr11_+_1244288 0.51 ENST00000529681.1
ENST00000447027.1
MUC5B
mucin 5B, oligomeric mucus/gel-forming
chr2_-_84686552 0.51 ENST00000393868.2
SUCLG1
succinate-CoA ligase, alpha subunit
chrX_-_19140677 0.51 ENST00000357544.3
ENST00000379869.3
ENST00000360279.4
ENST00000379873.2
ENST00000379878.3
ENST00000354791.3
ENST00000379876.1
GPR64
G protein-coupled receptor 64
chr16_+_30996502 0.51 ENST00000353250.5
ENST00000262520.6
ENST00000297679.5
ENST00000562932.1
ENST00000574447.1
HSD3B7
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
chr12_+_69080734 0.50 ENST00000378905.2
NUP107
nucleoporin 107kDa
chr15_+_66797455 0.50 ENST00000446801.2
ZWILCH
zwilch kinetochore protein
chr6_-_25874440 0.50 ENST00000361703.6
ENST00000397060.4
SLC17A3
solute carrier family 17 (organic anion transporter), member 3
chr14_-_50154921 0.50 ENST00000553805.2
ENST00000554396.1
ENST00000216367.5
ENST00000539565.2
POLE2
polymerase (DNA directed), epsilon 2, accessory subunit
chr19_+_35225060 0.48 ENST00000599244.1
ENST00000392232.3
ZNF181
zinc finger protein 181
chr4_+_155484155 0.48 ENST00000509493.1
FGB
fibrinogen beta chain
chrX_-_153775426 0.48 ENST00000393562.2
G6PD
glucose-6-phosphate dehydrogenase
chr17_+_41158742 0.48 ENST00000415816.2
ENST00000438323.2
IFI35
interferon-induced protein 35
chr3_+_151531810 0.48 ENST00000232892.7
AADAC
arylacetamide deacetylase
chr11_+_118272328 0.47 ENST00000524422.1
ATP5L
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G
chr3_-_124653579 0.47 ENST00000478191.1
ENST00000311075.3
MUC13
mucin 13, cell surface associated
chr10_+_90660832 0.47 ENST00000371924.1
STAMBPL1
STAM binding protein-like 1
chr5_-_67730240 0.47 ENST00000507733.1
CTC-537E7.3
CTC-537E7.3
chr22_+_25003626 0.46 ENST00000451366.1
ENST00000406383.2
ENST00000428855.1
GGT1
gamma-glutamyltransferase 1
chr19_-_40023450 0.46 ENST00000326282.4
EID2B
EP300 interacting inhibitor of differentiation 2B
chr4_+_15779901 0.46 ENST00000226279.3
CD38
CD38 molecule
chr1_-_94374946 0.46 ENST00000370238.3
GCLM
glutamate-cysteine ligase, modifier subunit
chr10_-_5046042 0.46 ENST00000421196.3
ENST00000455190.1
AKR1C2
aldo-keto reductase family 1, member C2
chr3_-_108308241 0.46 ENST00000295746.8
KIAA1524
KIAA1524
chr9_+_86238016 0.45 ENST00000530832.1
ENST00000405990.3
ENST00000376417.4
ENST00000376419.4
IDNK
idnK, gluconokinase homolog (E. coli)
chr3_+_160117087 0.45 ENST00000357388.3
SMC4
structural maintenance of chromosomes 4
chr12_+_3068544 0.45 ENST00000540314.1
ENST00000536826.1
ENST00000359864.2
TEAD4
TEA domain family member 4
chr11_+_74811578 0.45 ENST00000531713.1
SLCO2B1
solute carrier organic anion transporter family, member 2B1
chr2_+_196521458 0.44 ENST00000409086.3
SLC39A10
solute carrier family 39 (zinc transporter), member 10
chr3_+_160117418 0.44 ENST00000465903.1
ENST00000485645.1
ENST00000360111.2
ENST00000472991.1
ENST00000467468.1
ENST00000469762.1
ENST00000489573.1
ENST00000462787.1
ENST00000490207.1
ENST00000485867.1
SMC4
structural maintenance of chromosomes 4
chr19_+_2249308 0.44 ENST00000592877.1
ENST00000221496.4
AMH
anti-Mullerian hormone
chr1_+_242011468 0.44 ENST00000366548.3
EXO1
exonuclease 1
chr3_+_151531859 0.44 ENST00000488869.1
AADAC
arylacetamide deacetylase
chr19_+_35168547 0.44 ENST00000502743.1
ENST00000509528.1
ENST00000506901.1
ZNF302
zinc finger protein 302
chr10_+_6625605 0.43 ENST00000414894.1
ENST00000449648.1
PRKCQ-AS1
PRKCQ antisense RNA 1
chr17_-_73905899 0.43 ENST00000409963.3
MRPL38
mitochondrial ribosomal protein L38
chr3_+_142342228 0.43 ENST00000337777.3
PLS1
plastin 1
chr22_+_24999114 0.43 ENST00000412658.1
ENST00000445029.1
ENST00000419133.1
ENST00000400382.1
ENST00000438643.2
ENST00000452551.1
ENST00000400383.1
ENST00000412898.1
ENST00000400380.1
ENST00000455483.1
ENST00000430289.1
GGT1
gamma-glutamyltransferase 1
chr19_-_40331345 0.42 ENST00000597224.1
FBL
fibrillarin
chrY_+_22737678 0.42 ENST00000382772.3
EIF1AY
eukaryotic translation initiation factor 1A, Y-linked
chrX_+_106045891 0.42 ENST00000357242.5
ENST00000310452.2
ENST00000481617.2
ENST00000276175.3
TBC1D8B
TBC1 domain family, member 8B (with GRAM domain)
chr8_-_124741451 0.41 ENST00000520519.1
ANXA13
annexin A13
chr17_-_34207295 0.41 ENST00000463941.1
ENST00000293272.3
CCL5
chemokine (C-C motif) ligand 5
chr4_-_89079817 0.41 ENST00000505480.1
ABCG2
ATP-binding cassette, sub-family G (WHITE), member 2
chr4_-_89080362 0.41 ENST00000503830.1
ABCG2
ATP-binding cassette, sub-family G (WHITE), member 2
chr9_-_119162885 0.41 ENST00000445861.2
PAPPA-AS1
PAPPA antisense RNA 1
chr11_-_28129656 0.41 ENST00000263181.6
KIF18A
kinesin family member 18A
chr10_+_104629199 0.40 ENST00000369880.3
AS3MT
arsenic (+3 oxidation state) methyltransferase
chr9_-_15510989 0.40 ENST00000380715.1
ENST00000380716.4
ENST00000380738.4
ENST00000380733.4
PSIP1
PC4 and SFRS1 interacting protein 1
chr11_+_7618413 0.40 ENST00000528883.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr14_+_54863739 0.40 ENST00000541304.1
CDKN3
cyclin-dependent kinase inhibitor 3
chr10_+_6625733 0.40 ENST00000607982.1
ENST00000608526.1
PRKCQ-AS1
PRKCQ antisense RNA 1
chr17_-_59940830 0.40 ENST00000259008.2
BRIP1
BRCA1 interacting protein C-terminal helicase 1
chr2_-_38303218 0.40 ENST00000407341.1
ENST00000260630.3
CYP1B1
cytochrome P450, family 1, subfamily B, polypeptide 1
chr2_-_86094764 0.39 ENST00000393808.3
ST3GAL5
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
chr2_+_163200848 0.39 ENST00000233612.4
GCA
grancalcin, EF-hand calcium binding protein
chr9_+_86237963 0.39 ENST00000277124.8
IDNK
idnK, gluconokinase homolog (E. coli)
chr2_-_99917639 0.39 ENST00000308528.4
LYG1
lysozyme G-like 1
chr3_-_155462808 0.39 ENST00000460012.1
PLCH1
phospholipase C, eta 1
chr17_+_67498295 0.39 ENST00000589295.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr9_-_104145795 0.39 ENST00000259407.2
BAAT
bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase)
chr1_-_153521597 0.38 ENST00000368712.1
S100A3
S100 calcium binding protein A3
chr20_+_30327063 0.38 ENST00000300403.6
ENST00000340513.4
TPX2
TPX2, microtubule-associated
chr20_-_17539456 0.38 ENST00000544874.1
ENST00000377868.2
BFSP1
beaded filament structural protein 1, filensin
chr15_+_89787180 0.37 ENST00000300027.8
ENST00000310775.7
ENST00000567891.1
ENST00000564920.1
ENST00000565255.1
ENST00000567996.1
ENST00000451393.2
ENST00000563250.1
FANCI
Fanconi anemia, complementation group I
chr17_-_39341594 0.37 ENST00000398472.1
KRTAP4-1
keratin associated protein 4-1
chr10_+_26727125 0.37 ENST00000376236.4
APBB1IP
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr4_-_38858428 0.37 ENST00000436693.2
ENST00000508254.1
ENST00000514655.1
ENST00000506146.1
TLR6
TLR1
toll-like receptor 6
toll-like receptor 1
chr14_+_54863682 0.37 ENST00000543789.2
ENST00000442975.2
ENST00000458126.2
ENST00000556102.2
CDKN3
cyclin-dependent kinase inhibitor 3
chr15_-_78526942 0.37 ENST00000258873.4
ACSBG1
acyl-CoA synthetase bubblegum family member 1
chr18_+_20714525 0.37 ENST00000400473.2
CABLES1
Cdk5 and Abl enzyme substrate 1
chr10_+_94594351 0.36 ENST00000371552.4
EXOC6
exocyst complex component 6
chr20_-_52790512 0.36 ENST00000216862.3
CYP24A1
cytochrome P450, family 24, subfamily A, polypeptide 1
chr16_-_29479154 0.36 ENST00000549950.1
RP11-345J4.3
Uncharacterized protein
chr3_-_123512688 0.36 ENST00000475616.1
MYLK
myosin light chain kinase
chr20_+_5987890 0.36 ENST00000378868.4
CRLS1
cardiolipin synthase 1
chr12_+_72058130 0.36 ENST00000547843.1
THAP2
THAP domain containing, apoptosis associated protein 2
chr20_-_52790055 0.36 ENST00000395955.3
CYP24A1
cytochrome P450, family 24, subfamily A, polypeptide 1
chr15_-_56757329 0.35 ENST00000260453.3
MNS1
meiosis-specific nuclear structural 1
chr3_-_186080012 0.35 ENST00000544847.1
ENST00000265022.3
DGKG
diacylglycerol kinase, gamma 90kDa
chr7_+_139528952 0.35 ENST00000416849.2
ENST00000436047.2
ENST00000414508.2
ENST00000448866.1
TBXAS1
thromboxane A synthase 1 (platelet)
chr5_-_140013275 0.35 ENST00000512545.1
ENST00000302014.6
ENST00000401743.2
CD14
CD14 molecule
chr9_-_99180597 0.35 ENST00000375256.4
ZNF367
zinc finger protein 367
chr19_-_11456872 0.35 ENST00000586218.1
TMEM205
transmembrane protein 205
chr9_+_97766409 0.35 ENST00000425634.2
C9orf3
chromosome 9 open reading frame 3
chr5_-_59783882 0.35 ENST00000505507.2
ENST00000502484.2
PDE4D
phosphodiesterase 4D, cAMP-specific
chr1_+_43824669 0.35 ENST00000372462.1
CDC20
cell division cycle 20
chr1_+_66796401 0.35 ENST00000528771.1
PDE4B
phosphodiesterase 4B, cAMP-specific
chrX_-_107334790 0.34 ENST00000217958.3
PSMD10
proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
chr17_+_57784826 0.34 ENST00000262291.4
VMP1
vacuole membrane protein 1
chr12_+_66696322 0.34 ENST00000247815.4
HELB
helicase (DNA) B
chr22_+_25003606 0.34 ENST00000432867.1
GGT1
gamma-glutamyltransferase 1
chr15_+_48624300 0.34 ENST00000455976.2
ENST00000559540.1
DUT
deoxyuridine triphosphatase
chrX_+_24711997 0.34 ENST00000379068.3
ENST00000379059.3
POLA1
polymerase (DNA directed), alpha 1, catalytic subunit
chr14_-_80678512 0.34 ENST00000553968.1
DIO2
deiodinase, iodothyronine, type II
chr2_+_87754989 0.33 ENST00000409898.2
ENST00000419680.2
ENST00000414584.1
ENST00000455131.1
LINC00152
long intergenic non-protein coding RNA 152
chr1_-_17216109 0.33 ENST00000416869.1
RP11-108M9.4
RP11-108M9.4
chr1_-_17216143 0.33 ENST00000457075.1
RP11-108M9.4
RP11-108M9.4
chr1_+_242011485 0.33 ENST00000423131.1
ENST00000523590.1
EXO1
exonuclease 1
chr1_+_43824577 0.32 ENST00000310955.6
CDC20
cell division cycle 20
chr14_+_54863667 0.32 ENST00000335183.6
CDKN3
cyclin-dependent kinase inhibitor 3
chr11_-_115127611 0.32 ENST00000545094.1
CADM1
cell adhesion molecule 1
chr2_-_148778323 0.32 ENST00000440042.1
ENST00000535373.1
ENST00000540442.1
ENST00000536575.1
ORC4
origin recognition complex, subunit 4
chr8_-_123139423 0.32 ENST00000523792.1
RP11-398G24.2
RP11-398G24.2
chr1_-_230850043 0.32 ENST00000366667.4
AGT
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr16_+_19422035 0.32 ENST00000381414.4
ENST00000396229.2
TMC5
transmembrane channel-like 5
chr19_+_34287751 0.32 ENST00000590771.1
ENST00000589786.1
ENST00000284006.6
ENST00000588881.1
KCTD15
potassium channel tetramerization domain containing 15
chr5_-_179499108 0.32 ENST00000521389.1
RNF130
ring finger protein 130
chr10_-_6622201 0.32 ENST00000539722.1
ENST00000397176.2
PRKCQ
protein kinase C, theta
chr20_+_42187608 0.32 ENST00000373100.1
SGK2
serum/glucocorticoid regulated kinase 2
chr17_-_63557759 0.32 ENST00000307078.5
AXIN2
axin 2
chr15_+_63414017 0.32 ENST00000413507.2
LACTB
lactamase, beta
chr2_-_20101385 0.32 ENST00000431392.1
TTC32
tetratricopeptide repeat domain 32
chr11_+_2920951 0.31 ENST00000347936.2
SLC22A18
solute carrier family 22, member 18
chr14_+_102196739 0.31 ENST00000556973.1
RP11-796G6.2
Uncharacterized protein
chr2_+_234294585 0.31 ENST00000447484.1
DGKD
diacylglycerol kinase, delta 130kDa
chr14_+_50065459 0.31 ENST00000318317.4
LRR1
leucine rich repeat protein 1
chr2_+_196521845 0.31 ENST00000359634.5
ENST00000412905.1
SLC39A10
solute carrier family 39 (zinc transporter), member 10
chr19_-_55660561 0.31 ENST00000587758.1
ENST00000356783.5
ENST00000291901.8
ENST00000588426.1
ENST00000588147.1
ENST00000536926.1
ENST00000588981.1
TNNT1
troponin T type 1 (skeletal, slow)
chr2_-_20101701 0.31 ENST00000402414.1
ENST00000333610.3
TTC32
tetratricopeptide repeat domain 32
chr16_-_3030407 0.31 ENST00000431515.2
ENST00000574385.1
ENST00000576268.1
ENST00000574730.1
ENST00000575632.1
ENST00000573944.1
ENST00000262300.8
PKMYT1
protein kinase, membrane associated tyrosine/threonine 1
chr16_-_19897455 0.31 ENST00000568214.1
ENST00000569479.1
GPRC5B
G protein-coupled receptor, family C, group 5, member B
chr17_-_30668887 0.31 ENST00000581747.1
ENST00000583334.1
ENST00000580558.1
C17orf75
chromosome 17 open reading frame 75
chr10_+_6779326 0.31 ENST00000417112.1
RP11-554I8.2
RP11-554I8.2
chr19_+_50191921 0.30 ENST00000420022.3
ADM5
adrenomedullin 5 (putative)
chr12_+_53443963 0.30 ENST00000546602.1
ENST00000552570.1
ENST00000549700.1
TENC1
tensin like C1 domain containing phosphatase (tensin 2)
chr5_-_58295712 0.30 ENST00000317118.8
PDE4D
phosphodiesterase 4D, cAMP-specific
chr2_-_28113217 0.30 ENST00000444339.2
RBKS
ribokinase
chr1_+_153631130 0.30 ENST00000368685.5
SNAPIN
SNAP-associated protein
chr1_-_245026388 0.30 ENST00000440865.1
HNRNPU
heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
chr3_-_160117035 0.30 ENST00000489004.1
ENST00000496589.1
IFT80
intraflagellar transport 80 homolog (Chlamydomonas)
chr16_-_30006922 0.30 ENST00000564026.1
HIRIP3
HIRA interacting protein 3
chr15_+_59910132 0.30 ENST00000559200.1
GCNT3
glucosaminyl (N-acetyl) transferase 3, mucin type
chr19_+_14444525 0.30 ENST00000588275.1
CTC-548K16.1
CTC-548K16.1
chr17_-_60005365 0.30 ENST00000444766.3
INTS2
integrator complex subunit 2
chr8_+_8559406 0.30 ENST00000519106.1
CLDN23
claudin 23
chr12_+_53443680 0.30 ENST00000314250.6
ENST00000451358.1
TENC1
tensin like C1 domain containing phosphatase (tensin 2)
chr22_+_25003568 0.30 ENST00000447416.1
GGT1
gamma-glutamyltransferase 1
chr16_-_8955601 0.30 ENST00000569398.1
ENST00000568968.1
CARHSP1
calcium regulated heat stable protein 1, 24kDa
chr14_+_21156915 0.30 ENST00000397990.4
ENST00000555597.1
ANG
RNASE4
angiogenin, ribonuclease, RNase A family, 5
ribonuclease, RNase A family, 4
chr2_+_28113583 0.30 ENST00000344773.2
ENST00000379624.1
ENST00000342045.2
ENST00000379632.2
ENST00000361704.2
BRE
brain and reproductive organ-expressed (TNFRSF1A modulator)
chr4_-_123843597 0.30 ENST00000510735.1
ENST00000304430.5
NUDT6
nudix (nucleoside diphosphate linked moiety X)-type motif 6
chr12_+_3068957 0.29 ENST00000543035.1
TEAD4
TEA domain family member 4
chr2_+_101591314 0.29 ENST00000450763.1
NPAS2
neuronal PAS domain protein 2
chr1_-_153521714 0.29 ENST00000368713.3
S100A3
S100 calcium binding protein A3
chr9_-_19149276 0.29 ENST00000434144.1
PLIN2
perilipin 2
chr15_-_65282274 0.29 ENST00000204566.2
SPG21
spastic paraplegia 21 (autosomal recessive, Mast syndrome)
chr5_+_127419449 0.29 ENST00000262461.2
ENST00000343225.4
SLC12A2
solute carrier family 12 (sodium/potassium/chloride transporter), member 2
chr14_+_61449076 0.29 ENST00000526105.1
SLC38A6
solute carrier family 38, member 6
chr4_-_123844084 0.29 ENST00000339154.2
NUDT6
nudix (nucleoside diphosphate linked moiety X)-type motif 6
chr10_-_72141330 0.29 ENST00000395011.1
ENST00000395010.1
LRRC20
leucine rich repeat containing 20
chr8_+_32405728 0.29 ENST00000523079.1
ENST00000338921.4
ENST00000356819.4
ENST00000287845.5
ENST00000341377.5
NRG1
neuregulin 1
chr17_-_5323480 0.29 ENST00000573584.1
NUP88
nucleoporin 88kDa
chr19_-_48759119 0.29 ENST00000522889.1
ENST00000520753.1
ENST00000519940.1
ENST00000519332.1
ENST00000521437.1
ENST00000520007.1
ENST00000521613.1
CARD8
caspase recruitment domain family, member 8

Network of associatons between targets according to the STRING database.

First level regulatory network of STAT5A

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.3 GO:1902998 regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.3 0.8 GO:2000502 negative regulation of natural killer cell chemotaxis(GO:2000502)
0.2 1.2 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.2 1.1 GO:1903613 regulation of protein tyrosine phosphatase activity(GO:1903613) positive regulation of protein tyrosine phosphatase activity(GO:1903615)
0.2 0.8 GO:0019521 aldonic acid metabolic process(GO:0019520) D-gluconate metabolic process(GO:0019521)
0.2 0.6 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.2 1.2 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.2 0.4 GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
0.2 0.7 GO:0042369 vitamin D catabolic process(GO:0042369)
0.2 0.7 GO:1904481 response to tetrahydrofolate(GO:1904481) cellular response to tetrahydrofolate(GO:1904482)
0.2 1.1 GO:0071725 toll-like receptor TLR1:TLR2 signaling pathway(GO:0038123) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.2 0.5 GO:0061181 regulation of chondrocyte development(GO:0061181)
0.2 0.9 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.2 0.8 GO:0060301 vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.1 0.4 GO:0007506 gonadal mesoderm development(GO:0007506)
0.1 0.4 GO:0045062 extrathymic T cell selection(GO:0045062)
0.1 0.4 GO:2001113 negative regulation of hepatocyte growth factor receptor signaling pathway(GO:1902203) regulation of cellular response to hepatocyte growth factor stimulus(GO:2001112) negative regulation of cellular response to hepatocyte growth factor stimulus(GO:2001113)
0.1 0.4 GO:0034963 box C/D snoRNA 3'-end processing(GO:0000494) box C/D snoRNA metabolic process(GO:0033967) box C/D snoRNA processing(GO:0034963) histone glutamine methylation(GO:1990258)
0.1 2.0 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 1.5 GO:0019344 cysteine biosynthetic process(GO:0019344)
0.1 0.4 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.1 1.1 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417)
0.1 0.8 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.1 0.8 GO:0034421 post-translational protein acetylation(GO:0034421)
0.1 0.4 GO:0000706 meiotic DNA double-strand break processing(GO:0000706) double-strand break repair involved in meiotic recombination(GO:1990918)
0.1 0.5 GO:0015785 UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
0.1 0.6 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.1 0.5 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.1 0.5 GO:0097069 cellular response to thyroxine stimulus(GO:0097069) cellular response to L-phenylalanine derivative(GO:1904387)
0.1 0.7 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.1 0.3 GO:0046081 dUTP metabolic process(GO:0046080) dUTP catabolic process(GO:0046081)
0.1 0.3 GO:1903410 lysine import(GO:0034226) L-lysine import(GO:0061461) L-lysine import into cell(GO:1903410)
0.1 0.5 GO:0072709 cellular response to sorbitol(GO:0072709)
0.1 0.4 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.1 0.9 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.1 0.3 GO:1902824 positive regulation of late endosome to lysosome transport(GO:1902824)
0.1 0.5 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.1 1.0 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.1 0.3 GO:0046103 adenosine catabolic process(GO:0006154) inosine biosynthetic process(GO:0046103)
0.1 0.4 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.1 0.3 GO:0014016 neuroblast differentiation(GO:0014016)
0.1 1.2 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.1 0.3 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.1 0.2 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.1 3.6 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.1 1.9 GO:0046415 urate metabolic process(GO:0046415)
0.1 0.3 GO:0071139 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
0.1 0.1 GO:0006286 base-excision repair, base-free sugar-phosphate removal(GO:0006286)
0.1 0.4 GO:0097068 response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
0.1 0.4 GO:0019303 D-ribose catabolic process(GO:0019303)
0.1 0.3 GO:0000961 negative regulation of mitochondrial RNA catabolic process(GO:0000961)
0.1 1.3 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 0.3 GO:2000569 T-helper 2 cell activation(GO:0035712) regulation of T-helper 2 cell activation(GO:2000569) positive regulation of T-helper 2 cell activation(GO:2000570)
0.1 0.2 GO:1990641 cellular response to bile acid(GO:1903413) negative regulation of intestinal absorption(GO:1904479) response to iron ion starvation(GO:1990641)
0.1 0.5 GO:0046125 thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.1 0.3 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.1 0.2 GO:0060629 meiotic DNA double-strand break formation(GO:0042138) regulation of homologous chromosome segregation(GO:0060629)
0.1 0.4 GO:0070124 mitochondrial translational initiation(GO:0070124)
0.1 0.2 GO:0061580 colon epithelial cell migration(GO:0061580)
0.1 0.2 GO:1990426 homologous recombination-dependent replication fork processing(GO:1990426)
0.1 0.6 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.1 0.2 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 0.2 GO:0002728 negative regulation of natural killer cell cytokine production(GO:0002728)
0.1 0.3 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.1 0.1 GO:0000960 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.1 0.6 GO:0006572 tyrosine catabolic process(GO:0006572)
0.1 1.0 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 0.2 GO:0014839 myoblast migration involved in skeletal muscle regeneration(GO:0014839)
0.1 0.1 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.1 0.5 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.1 0.4 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.1 0.2 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.1 0.1 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
0.1 0.4 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1 0.2 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.1 1.3 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.1 0.2 GO:0016340 calcium-dependent cell-matrix adhesion(GO:0016340)
0.1 0.2 GO:2000437 monocyte extravasation(GO:0035696) interleukin-15-mediated signaling pathway(GO:0035723) cellular response to interleukin-15(GO:0071350) regulation of fertilization(GO:0080154) activation of meiosis(GO:0090427) regulation of monocyte extravasation(GO:2000437)
0.1 0.5 GO:2000860 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.1 0.5 GO:0009753 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.1 0.1 GO:0018364 peptidyl-glutamine methylation(GO:0018364)
0.1 0.3 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.1 0.7 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.1 0.4 GO:0030885 regulation of myeloid dendritic cell activation(GO:0030885) regulation of osteoclast proliferation(GO:0090289)
0.1 0.2 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.1 0.1 GO:0044860 protein localization to plasma membrane raft(GO:0044860)
0.1 0.2 GO:1903925 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.1 0.2 GO:0052651 monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.1 0.6 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.1 0.2 GO:0008355 olfactory learning(GO:0008355)
0.1 0.4 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.1 0.2 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.0 0.2 GO:2001183 negative regulation of interleukin-10 secretion(GO:2001180) negative regulation of interleukin-12 secretion(GO:2001183)
0.0 0.2 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.0 1.0 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.2 GO:0015862 uridine transport(GO:0015862)
0.0 0.3 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.0 0.2 GO:0006447 regulation of translational initiation by iron(GO:0006447)
0.0 0.4 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.0 GO:0035378 carbon dioxide transmembrane transport(GO:0035378)
0.0 0.8 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.1 GO:0003032 detection of oxygen(GO:0003032)
0.0 0.2 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
0.0 0.2 GO:1903778 protein localization to vacuolar membrane(GO:1903778)
0.0 0.2 GO:2000110 negative regulation of macrophage apoptotic process(GO:2000110)
0.0 0.4 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0 0.1 GO:0034553 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.0 0.1 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.0 0.1 GO:0006147 guanine catabolic process(GO:0006147)
0.0 0.2 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.0 0.1 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.0 0.2 GO:0036015 response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016)
0.0 0.3 GO:0046618 drug export(GO:0046618)
0.0 0.3 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0 0.1 GO:0060262 regulation of N-terminal protein palmitoylation(GO:0060254) negative regulation of N-terminal protein palmitoylation(GO:0060262) negative regulation of protein lipidation(GO:1903060)
0.0 1.0 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.1 GO:0038163 endomitotic cell cycle(GO:0007113) thrombopoietin-mediated signaling pathway(GO:0038163)
0.0 0.3 GO:0090166 Golgi disassembly(GO:0090166)
0.0 0.7 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.0 0.2 GO:0098886 modification of dendritic spine(GO:0098886)
0.0 0.4 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.1 GO:0072308 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308)
0.0 0.3 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 0.4 GO:0019530 taurine metabolic process(GO:0019530)
0.0 0.2 GO:1902896 terminal web assembly(GO:1902896)
0.0 0.7 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.1 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
0.0 0.7 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.2 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.0 0.1 GO:0046603 negative regulation of mitotic centrosome separation(GO:0046603)
0.0 0.3 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.0 0.5 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.6 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.1 GO:0071418 cellular response to amine stimulus(GO:0071418)
0.0 0.1 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.0 0.2 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.0 1.0 GO:0006825 copper ion transport(GO:0006825)
0.0 0.2 GO:1903826 arginine transmembrane transport(GO:1903826)
0.0 0.2 GO:0052422 modulation by symbiont of host molecular function(GO:0052055) modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.0 0.1 GO:0009386 translational attenuation(GO:0009386)
0.0 0.2 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.0 0.2 GO:0060480 lung goblet cell differentiation(GO:0060480)
0.0 0.3 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.4 GO:0072520 seminiferous tubule development(GO:0072520)
0.0 0.4 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.3 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.1 GO:0006480 N-terminal protein amino acid methylation(GO:0006480)
0.0 0.3 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.2 GO:0010911 regulation of isomerase activity(GO:0010911) positive regulation of isomerase activity(GO:0010912) regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373)
0.0 0.5 GO:0045779 negative regulation of bone resorption(GO:0045779)
0.0 0.2 GO:1990034 calcium ion export from cell(GO:1990034)
0.0 0.1 GO:1902161 positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)
0.0 0.3 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.1 GO:0003335 corneocyte development(GO:0003335)
0.0 0.3 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 0.2 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0 0.1 GO:0036371 protein localization to T-tubule(GO:0036371)
0.0 0.1 GO:0046968 peptide antigen transport(GO:0046968)
0.0 0.7 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.0 0.1 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.1 GO:0006382 adenosine to inosine editing(GO:0006382)
0.0 0.4 GO:0048671 negative regulation of collateral sprouting(GO:0048671)
0.0 0.6 GO:0070986 left/right axis specification(GO:0070986)
0.0 0.0 GO:0030101 natural killer cell activation(GO:0030101)
0.0 0.4 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.2 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 1.1 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.0 0.1 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.0 0.1 GO:0045925 positive regulation of female receptivity(GO:0045925) positive regulation of penile erection(GO:0060406)
0.0 0.1 GO:0071314 cellular response to cocaine(GO:0071314) positive regulation of corticosterone secretion(GO:2000854)
0.0 0.3 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 1.1 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.2 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.1 GO:1905026 positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903762) positive regulation of ventricular cardiac muscle cell action potential(GO:1903947) positive regulation of membrane repolarization during ventricular cardiac muscle cell action potential(GO:1905026) positive regulation of membrane repolarization during cardiac muscle cell action potential(GO:1905033)
0.0 0.0 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.0 0.1 GO:0002378 immunoglobulin biosynthetic process(GO:0002378) negative regulation of glucose import in response to insulin stimulus(GO:2001274)
0.0 0.1 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.0 0.1 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.0 0.2 GO:0035754 B cell chemotaxis(GO:0035754)
0.0 0.1 GO:0019427 acetate biosynthetic process(GO:0019413) acetyl-CoA biosynthetic process from acetate(GO:0019427) propionate metabolic process(GO:0019541) propionate biosynthetic process(GO:0019542)
0.0 0.0 GO:0007509 mesoderm migration involved in gastrulation(GO:0007509)
0.0 0.2 GO:0072592 oxygen metabolic process(GO:0072592)
0.0 0.3 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.0 0.1 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.0 0.2 GO:0045591 positive regulation of regulatory T cell differentiation(GO:0045591)
0.0 0.1 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.0 0.4 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.0 GO:0015855 pyrimidine nucleobase transport(GO:0015855) purine nucleobase transmembrane transport(GO:1904823)
0.0 0.3 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.1 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.2 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.1 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 0.4 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.2 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.1 GO:0002940 tRNA N2-guanine methylation(GO:0002940)
0.0 0.2 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.0 0.0 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.0 0.1 GO:0098968 neurotransmitter receptor transport postsynaptic membrane to endosome(GO:0098968)
0.0 1.0 GO:0071431 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.0 0.3 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0 0.3 GO:1901642 nucleoside transmembrane transport(GO:1901642)
0.0 0.1 GO:0046878 positive regulation of saliva secretion(GO:0046878)
0.0 0.1 GO:2000354 regulation of ovarian follicle development(GO:2000354)
0.0 0.1 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.1 GO:0060671 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.0 0.2 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.1 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.0 GO:0048250 mitochondrial iron ion transport(GO:0048250)
0.0 0.1 GO:0019853 L-ascorbic acid biosynthetic process(GO:0019853)
0.0 0.2 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.0 0.0 GO:0060061 Spemann organizer formation(GO:0060061)
0.0 0.1 GO:0071504 cellular response to heparin(GO:0071504)
0.0 0.3 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.1 GO:2001222 regulation of neuron migration(GO:2001222)
0.0 0.4 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.8 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 0.8 GO:0042339 keratan sulfate metabolic process(GO:0042339)
0.0 0.1 GO:0034499 late endosome to Golgi transport(GO:0034499)
0.0 0.2 GO:1901750 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.0 0.3 GO:0035330 regulation of hippo signaling(GO:0035330)
0.0 0.1 GO:0021514 ventral spinal cord interneuron differentiation(GO:0021514)
0.0 0.1 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.0 GO:0006710 androgen catabolic process(GO:0006710)
0.0 0.6 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 0.2 GO:0038065 collagen-activated signaling pathway(GO:0038065)
0.0 0.2 GO:0007059 chromosome segregation(GO:0007059)
0.0 0.1 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
0.0 0.7 GO:0035329 hippo signaling(GO:0035329)
0.0 0.0 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.0 0.3 GO:0071294 cellular response to zinc ion(GO:0071294)
0.0 0.5 GO:0034629 cellular protein complex localization(GO:0034629)
0.0 0.4 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.0 0.3 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.0 0.6 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.1 GO:0032525 somite specification(GO:0001757) somite rostral/caudal axis specification(GO:0032525)
0.0 0.3 GO:0048266 behavioral response to pain(GO:0048266)
0.0 0.9 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.2 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.0 0.4 GO:0009404 toxin metabolic process(GO:0009404)
0.0 0.1 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.2 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.1 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.1 GO:1902460 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.0 0.1 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.1 GO:0098909 regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.0 0.1 GO:0070836 caveola assembly(GO:0070836)
0.0 0.1 GO:0060056 mammary gland involution(GO:0060056)
0.0 0.2 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.2 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.0 GO:1903286 regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288)
0.0 0.1 GO:0016180 snRNA processing(GO:0016180)
0.0 0.0 GO:0045554 TRAIL biosynthetic process(GO:0045553) regulation of TRAIL biosynthetic process(GO:0045554) positive regulation of TRAIL biosynthetic process(GO:0045556)
0.0 0.1 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.0 GO:1901318 negative regulation of sperm motility(GO:1901318)
0.0 0.5 GO:2000179 positive regulation of neural precursor cell proliferation(GO:2000179)
0.0 0.1 GO:1902715 secretory granule localization(GO:0032252) positive regulation of interferon-gamma secretion(GO:1902715)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.1 GO:1990423 RZZ complex(GO:1990423)
0.2 0.8 GO:0071062 rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.2 1.0 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.2 3.3 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.1 0.5 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.1 0.3 GO:0071821 FANCM-MHF complex(GO:0071821)
0.1 0.5 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.1 0.9 GO:0005579 membrane attack complex(GO:0005579)
0.1 0.5 GO:0070701 mucus layer(GO:0070701)
0.1 0.7 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.1 1.3 GO:0005577 fibrinogen complex(GO:0005577)
0.1 1.2 GO:0000796 condensin complex(GO:0000796)
0.1 0.3 GO:0097543 ciliary inversin compartment(GO:0097543)
0.1 0.3 GO:0032839 dendrite cytoplasm(GO:0032839)
0.1 0.4 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 0.2 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.8 GO:0097443 sorting endosome(GO:0097443)
0.1 0.4 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.1 0.4 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.1 0.4 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.1 0.2 GO:0000438 core TFIIH complex portion of holo TFIIH complex(GO:0000438)
0.1 0.5 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 0.4 GO:1990357 terminal web(GO:1990357)
0.1 0.6 GO:0072687 meiotic spindle(GO:0072687)
0.1 0.8 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.2 GO:0034681 integrin alpha11-beta1 complex(GO:0034681)
0.0 0.8 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.3 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.0 0.2 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.2 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.7 GO:0032039 integrator complex(GO:0032039)
0.0 1.0 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.1 GO:0034455 t-UTP complex(GO:0034455)
0.0 0.6 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.4 GO:0042382 paraspeckles(GO:0042382)
0.0 1.2 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.6 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 1.0 GO:0043194 axon initial segment(GO:0043194)
0.0 0.7 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.2 GO:0002079 inner acrosomal membrane(GO:0002079)
0.0 0.2 GO:1990246 uniplex complex(GO:1990246)
0.0 0.2 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 0.1 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.0 0.2 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.0 0.2 GO:0045179 apical cortex(GO:0045179)
0.0 0.9 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.4 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 1.3 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.4 GO:0005882 intermediate filament(GO:0005882)
0.0 0.3 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.0 0.5 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.2 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.2 GO:0000923 equatorial microtubule organizing center(GO:0000923)
0.0 0.1 GO:0031251 PAN complex(GO:0031251)
0.0 0.2 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.3 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.9 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.2 GO:0071953 elastic fiber(GO:0071953)
0.0 0.3 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.3 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.0 0.4 GO:0043203 axon hillock(GO:0043203)
0.0 0.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.6 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.2 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 0.5 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.1 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.1 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.0 0.7 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.1 GO:0097224 sperm connecting piece(GO:0097224)
0.0 0.7 GO:0000145 exocyst(GO:0000145)
0.0 0.0 GO:0005816 spindle pole body(GO:0005816)
0.0 0.4 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.1 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.0 0.1 GO:0000798 nuclear cohesin complex(GO:0000798)
0.0 0.1 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.1 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.0 0.3 GO:0001741 XY body(GO:0001741)
0.0 0.0 GO:0031985 Golgi cisterna(GO:0031985) Golgi cisterna membrane(GO:0032580)
0.0 0.2 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.3 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.0 GO:0036398 TCR signalosome(GO:0036398)
0.0 1.1 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.0 GO:0098855 HCN channel complex(GO:0098855)
0.0 0.1 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.6 GO:0005813 centrosome(GO:0005813)
0.0 0.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.2 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.3 GO:0005861 troponin complex(GO:0005861)
0.0 0.1 GO:0000974 Prp19 complex(GO:0000974)
0.0 0.2 GO:0000800 lateral element(GO:0000800)
0.0 0.8 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.0 GO:0045257 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.1 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.4 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.9 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.1 GO:0097440 apical dendrite(GO:0097440)
0.0 0.6 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 2.1 GO:0072562 blood microparticle(GO:0072562)
0.0 0.1 GO:0001739 sex chromatin(GO:0001739)
0.0 0.3 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 0.3 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.2 GO:0031092 platelet alpha granule membrane(GO:0031092)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0051908 double-stranded DNA 5'-3' exodeoxyribonuclease activity(GO:0051908)
0.2 0.7 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.2 0.7 GO:0036134 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.2 0.5 GO:0050135 NAD(P)+ nucleosidase activity(GO:0050135)
0.1 1.7 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 0.7 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.1 0.7 GO:0070905 serine binding(GO:0070905)
0.1 0.4 GO:1990259 protein-glutamine N-methyltransferase activity(GO:0036009) histone-glutamine methyltransferase activity(GO:1990259)
0.1 1.2 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.1 0.4 GO:0047291 neolactotetraosylceramide alpha-2,3-sialyltransferase activity(GO:0004513) lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291)
0.1 1.4 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.1 3.7 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.1 0.7 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.1 0.4 GO:0050429 calcium-dependent phospholipase C activity(GO:0050429)
0.1 0.5 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.1 1.1 GO:0071723 lipopeptide binding(GO:0071723)
0.1 0.4 GO:0043337 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572) CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity(GO:0043337)
0.1 0.5 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.1 0.3 GO:0017116 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116)
0.1 0.3 GO:0004170 dUTP diphosphatase activity(GO:0004170)
0.1 0.4 GO:0001884 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
0.1 0.5 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.1 0.3 GO:0047225 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0047225)
0.1 0.3 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.1 3.3 GO:0051787 misfolded protein binding(GO:0051787)
0.1 0.5 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.1 0.8 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.1 0.3 GO:0035248 alpha-1,4-N-acetylgalactosaminyltransferase activity(GO:0035248)
0.1 1.7 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.1 0.4 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.1 0.5 GO:0004797 thymidine kinase activity(GO:0004797)
0.1 0.5 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.1 0.5 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.1 0.4 GO:0004905 type I interferon receptor activity(GO:0004905)
0.1 0.7 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.1 0.7 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.1 0.2 GO:0004423 iduronate-2-sulfatase activity(GO:0004423)
0.1 0.6 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.1 0.3 GO:0036033 mediator complex binding(GO:0036033)
0.1 1.6 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1 0.3 GO:0031493 nucleosomal histone binding(GO:0031493)
0.1 0.5 GO:0018636 phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086)
0.1 0.5 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.1 0.2 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.1 0.4 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.1 0.6 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.1 0.2 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.1 0.2 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.1 0.2 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.1 0.2 GO:0047708 biotinidase activity(GO:0047708)
0.1 0.8 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.1 0.8 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.1 0.3 GO:0015307 drug:proton antiporter activity(GO:0015307)
0.1 0.4 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 1.0 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.5 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.3 GO:0032089 NACHT domain binding(GO:0032089)
0.0 0.2 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.4 GO:1990932 5.8S rRNA binding(GO:1990932)
0.0 0.3 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.0 0.1 GO:0008892 guanine deaminase activity(GO:0008892)
0.0 0.3 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.2 GO:0001632 leukotriene B4 receptor activity(GO:0001632)
0.0 0.1 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.0 0.5 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.1 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.0 0.2 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.1 GO:0044715 8-oxo-dGDP phosphatase activity(GO:0044715)
0.0 0.4 GO:0003796 lysozyme activity(GO:0003796)
0.0 1.0 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 1.4 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.1 GO:0045518 interleukin-22 receptor binding(GO:0045518)
0.0 0.1 GO:0005174 CD40 receptor binding(GO:0005174)
0.0 0.1 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.0 0.3 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.0 0.1 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.0 0.7 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.9 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 1.1 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.2 GO:0016972 thiol oxidase activity(GO:0016972)
0.0 0.2 GO:0004473 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.0 0.1 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
0.0 0.5 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.6 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.1 GO:0008441 3'(2'),5'-bisphosphate nucleotidase activity(GO:0008441)
0.0 0.2 GO:0010853 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.0 0.3 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.1 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.0 0.5 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 1.2 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.1 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.0 0.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.3 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.8 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.1 GO:0004139 deoxyribose-phosphate aldolase activity(GO:0004139)
0.0 0.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.7 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.2 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 0.2 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.2 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.2 GO:0017018 myosin phosphatase activity(GO:0017018)
0.0 0.3 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.1 GO:0008386 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386)
0.0 0.2 GO:0004127 cytidylate kinase activity(GO:0004127)
0.0 0.3 GO:0031014 troponin T binding(GO:0031014)
0.0 0.3 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.0 0.7 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.6 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.3 GO:0097100 supercoiled DNA binding(GO:0097100)
0.0 0.2 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.0 0.3 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 0.3 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.3 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.1 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.0 0.1 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.3 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.1 GO:0004911 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.0 0.1 GO:0030626 U12 snRNA binding(GO:0030626)
0.0 0.3 GO:1990825 G-quadruplex RNA binding(GO:0002151) sequence-specific mRNA binding(GO:1990825)
0.0 0.1 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.9 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.3 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.2 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.5 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.0 GO:0051538 succinate dehydrogenase (ubiquinone) activity(GO:0008177) 3 iron, 4 sulfur cluster binding(GO:0051538)
0.0 0.1 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.0 0.1 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0 1.2 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.2 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0 0.0 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.1 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.2 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.3 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.2 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.0 GO:0005148 prolactin receptor binding(GO:0005148)
0.0 0.2 GO:0036310 annealing helicase activity(GO:0036310) annealing activity(GO:0097617)
0.0 0.1 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.2 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.2 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.1 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0 0.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.3 GO:0008009 chemokine activity(GO:0008009)
0.0 0.3 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.6 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.4 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.0 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.0 0.1 GO:0046790 virion binding(GO:0046790)
0.0 0.1 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.5 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.1 GO:0004522 ribonuclease A activity(GO:0004522)
0.0 0.1 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.3 GO:0031402 sodium ion binding(GO:0031402)
0.0 0.5 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.4 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.3 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.1 GO:0008428 ribonuclease inhibitor activity(GO:0008428)
0.0 0.2 GO:0070330 aromatase activity(GO:0070330)
0.0 0.1 GO:0010465 nerve growth factor receptor activity(GO:0010465)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 1.9 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.5 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 1.3 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.6 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 1.8 PID AURORA B PATHWAY Aurora B signaling
0.0 0.4 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.6 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 1.7 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.2 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 1.3 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 2.8 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.5 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 1.1 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.8 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.4 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.1 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.2 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 1.4 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.8 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.4 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 1.7 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1 2.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 1.4 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.1 0.3 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.1 1.2 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 2.8 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.4 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 2.0 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.6 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 1.3 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 0.8 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.4 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 1.2 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.4 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.6 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.0 0.7 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 1.4 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.9 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 1.2 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 1.7 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 1.1 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 0.3 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.3 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.1 REACTOME DEFENSINS Genes involved in Defensins
0.0 0.5 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.9 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.6 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.3 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.6 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.3 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.2 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.3 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.5 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 1.0 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.6 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 2.7 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.4 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.8 REACTOME KERATAN SULFATE KERATIN METABOLISM Genes involved in Keratan sulfate/keratin metabolism
0.0 2.1 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.9 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.2 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.7 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.2 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.5 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.3 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.3 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.1 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.3 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.8 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.6 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.3 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.3 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.4 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism