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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for STAT6

Z-value: 0.51

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Transcription factors associated with STAT6

Gene Symbol Gene ID Gene Info
ENSG00000166888.6 signal transducer and activator of transcription 6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
STAT6hg19_v2_chr12_-_57504975_575050190.551.2e-02Click!

Activity profile of STAT6 motif

Sorted Z-values of STAT6 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_-_151066514 1.27 ENST00000538026.1
ENST00000522348.1
ENST00000521569.1
secreted protein, acidic, cysteine-rich (osteonectin)
chr2_+_113885138 0.94 ENST00000409930.3
interleukin 1 receptor antagonist
chr17_-_39681578 0.93 ENST00000593096.1
keratin 19
chr1_-_36020531 0.89 ENST00000440579.1
ENST00000494948.1
KIAA0319-like
chr1_-_209824643 0.78 ENST00000391911.1
ENST00000415782.1
laminin, beta 3
chr3_+_189507523 0.73 ENST00000437221.1
ENST00000392463.2
ENST00000392461.3
ENST00000449992.1
ENST00000456148.1
tumor protein p63
chr7_-_38969150 0.72 ENST00000418457.2
vacuolar protein sorting 41 homolog (S. cerevisiae)
chr13_+_73629107 0.63 ENST00000539231.1
Kruppel-like factor 5 (intestinal)
chr15_-_23932437 0.63 ENST00000331837.4
necdin, melanoma antigen (MAGE) family member
chr3_+_189507460 0.61 ENST00000434928.1
tumor protein p63
chr11_-_14379997 0.57 ENST00000526063.1
ENST00000532814.1
related RAS viral (r-ras) oncogene homolog 2
chr3_+_41236325 0.57 ENST00000426215.1
ENST00000405570.1
catenin (cadherin-associated protein), beta 1, 88kDa
chr2_+_191792376 0.56 ENST00000409428.1
ENST00000409215.1
glutaminase
chrX_+_100878112 0.52 ENST00000491568.2
ENST00000479298.1
armadillo repeat containing, X-linked 3
chr3_+_189507432 0.51 ENST00000354600.5
tumor protein p63
chr1_-_179834311 0.49 ENST00000553856.1
Homo sapiens torsin A interacting protein 2 (TOR1AIP2), transcript variant 1, mRNA.
chr2_+_219745020 0.48 ENST00000258411.3
wingless-type MMTV integration site family, member 10A
chr14_-_24733444 0.48 ENST00000560478.1
ENST00000560443.1
transglutaminase 1
chr2_-_230786378 0.48 ENST00000430954.1
thyroid hormone receptor interactor 12
chr18_+_33161698 0.45 ENST00000591924.1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1)
chr11_-_128457446 0.44 ENST00000392668.4
v-ets avian erythroblastosis virus E26 oncogene homolog 1
chr1_+_32608566 0.43 ENST00000545542.1
karyopherin alpha 6 (importin alpha 7)
chr2_-_230786032 0.43 ENST00000428959.1
thyroid hormone receptor interactor 12
chr14_-_24732738 0.41 ENST00000558074.1
ENST00000560226.1
transglutaminase 1
chr1_-_41328018 0.39 ENST00000372638.2
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4
chr1_+_78383813 0.39 ENST00000342754.5
nexilin (F actin binding protein)
chr5_+_110427983 0.38 ENST00000513710.2
ENST00000505303.1
WD repeat domain 36
chr2_-_31440377 0.37 ENST00000444918.2
ENST00000403897.3
calpain 14
chr2_-_134326009 0.37 ENST00000409261.1
ENST00000409213.1
NCK-associated protein 5
chr12_-_46663734 0.36 ENST00000550173.1
solute carrier family 38, member 1
chr1_+_89246647 0.35 ENST00000544045.1
protein kinase N2
chr19_+_13228917 0.34 ENST00000586171.1
nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
chr1_-_153321301 0.33 ENST00000368739.3
peptidoglycan recognition protein 4
chr8_-_117886732 0.32 ENST00000517485.1
RAD21 homolog (S. pombe)
chr9_-_3469181 0.32 ENST00000366116.2
Uncharacterized protein
chr5_+_667759 0.32 ENST00000594226.1
Uncharacterized protein
chr12_-_118490403 0.32 ENST00000535496.1
WD repeat and SOCS box containing 2
chr14_+_55034599 0.31 ENST00000392067.3
ENST00000357634.3
sterile alpha motif domain containing 4A
chr6_+_138188378 0.30 ENST00000420009.1
tumor necrosis factor, alpha-induced protein 3
chr4_+_30721968 0.29 ENST00000361762.2
protocadherin 7
chr1_-_108735440 0.29 ENST00000370041.4
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
chr2_+_182756915 0.28 ENST00000428267.2
sperm specific antigen 2
chr15_+_40731920 0.28 ENST00000561234.1
bromo adjacent homology domain containing 1
chr5_+_102201687 0.28 ENST00000304400.7
peptidylglycine alpha-amidating monooxygenase
chr1_-_205391178 0.27 ENST00000367153.4
ENST00000367151.2
ENST00000391936.2
ENST00000367149.3
LEM domain containing 1
chr8_+_104311059 0.27 ENST00000358755.4
ENST00000523739.1
ENST00000540287.1
frizzled family receptor 6
chr6_+_147527103 0.27 ENST00000179882.6
syntaxin binding protein 5 (tomosyn)
chrX_-_73051037 0.27 ENST00000445814.1
X inactive specific transcript (non-protein coding)
chr19_+_38924316 0.26 ENST00000355481.4
ENST00000360985.3
ENST00000359596.3
ryanodine receptor 1 (skeletal)
chr13_-_74708372 0.25 ENST00000377666.4
Kruppel-like factor 12
chr5_+_102201722 0.24 ENST00000274392.9
ENST00000455264.2
peptidylglycine alpha-amidating monooxygenase
chrX_+_100878079 0.24 ENST00000471229.2
armadillo repeat containing, X-linked 3
chr3_-_37218023 0.24 ENST00000416425.1
leucine rich repeat (in FLII) interacting protein 2
chr2_+_182756615 0.24 ENST00000431877.2
ENST00000320370.7
sperm specific antigen 2
chr16_+_30076052 0.23 ENST00000563987.1
aldolase A, fructose-bisphosphate
chr2_-_230786619 0.23 ENST00000389045.3
ENST00000409677.1
thyroid hormone receptor interactor 12
chrX_-_138914394 0.23 ENST00000327569.3
ENST00000361648.2
ENST00000370543.1
ENST00000359686.2
ATPase, class VI, type 11C
chr1_-_116383738 0.23 ENST00000320238.3
nescient helix loop helix 2
chr1_+_114472481 0.22 ENST00000369555.2
homeodomain interacting protein kinase 1
chr1_+_45965725 0.22 ENST00000401061.4
methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
chr21_+_42539701 0.22 ENST00000330333.6
ENST00000328735.6
ENST00000347667.5
beta-site APP-cleaving enzyme 2
chr4_+_144312659 0.21 ENST00000509992.1
GRB2-associated binding protein 1
chr16_+_82090028 0.21 ENST00000568090.1
hydroxysteroid (17-beta) dehydrogenase 2
chr2_-_16804320 0.21 ENST00000355549.2
family with sequence similarity 49, member A
chr5_+_35856951 0.21 ENST00000303115.3
ENST00000343305.4
ENST00000506850.1
ENST00000511982.1
interleukin 7 receptor
chr17_-_48277552 0.21 ENST00000507689.1
collagen, type I, alpha 1
chr12_-_118490217 0.20 ENST00000542304.1
WD repeat and SOCS box containing 2
chr2_+_131769256 0.20 ENST00000355771.3
Rho guanine nucleotide exchange factor (GEF) 4
chr6_+_26440700 0.20 ENST00000494393.1
ENST00000482451.1
ENST00000244519.2
ENST00000339789.4
ENST00000471353.1
ENST00000361232.3
ENST00000487627.1
ENST00000496719.1
ENST00000490254.1
ENST00000487272.1
butyrophilin, subfamily 3, member A3
chr6_+_138188351 0.20 ENST00000421450.1
tumor necrosis factor, alpha-induced protein 3
chr3_+_141121164 0.19 ENST00000510338.1
ENST00000504673.1
zinc finger and BTB domain containing 38
chr11_+_118230287 0.19 ENST00000252108.3
ENST00000431736.2
ubiquitination factor E4A
chr1_-_147245484 0.18 ENST00000271348.2
gap junction protein, alpha 5, 40kDa
chr2_-_190044480 0.18 ENST00000374866.3
collagen, type V, alpha 2
chr1_+_45274154 0.18 ENST00000450269.1
ENST00000453418.1
ENST00000409335.2
BTB (POZ) domain containing 19
chr1_-_68299130 0.18 ENST00000370982.3
guanine nucleotide binding protein (G protein), gamma 12
chr1_+_82165350 0.17 ENST00000359929.3
latrophilin 2
chr17_+_7461580 0.17 ENST00000483039.1
ENST00000396542.1
tumor necrosis factor (ligand) superfamily, member 13
chr11_-_10828892 0.17 ENST00000525681.1
eukaryotic translation initiation factor 4 gamma, 2
chr6_-_33754778 0.17 ENST00000508327.1
ENST00000513701.1
LEM domain containing 2
chr12_+_26164645 0.16 ENST00000542004.1
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
chr17_+_7462031 0.16 ENST00000380535.4
tumor necrosis factor (ligand) superfamily, member 13
chr17_-_62308087 0.16 ENST00000583097.1
testis expressed 2
chr4_-_120988229 0.15 ENST00000296509.6
MAD2 mitotic arrest deficient-like 1 (yeast)
chr5_+_138609441 0.15 ENST00000509990.1
ENST00000506147.1
ENST00000512107.1
matrin 3
chr2_-_109605663 0.14 ENST00000409271.1
ENST00000258443.2
ENST00000376651.1
ectodysplasin A receptor
chr17_+_7461613 0.14 ENST00000438470.1
ENST00000436057.1
tumor necrosis factor (ligand) superfamily, member 13
chr8_+_55466915 0.14 ENST00000522711.2
RP11-53M11.3
chr19_+_13229126 0.14 ENST00000292431.4
nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
chr3_+_63898275 0.14 ENST00000538065.1
ataxin 7
chr1_+_150245099 0.14 ENST00000369099.3
chromosome 1 open reading frame 54
chr1_+_114472222 0.14 ENST00000369558.1
ENST00000369561.4
homeodomain interacting protein kinase 1
chrX_+_135251835 0.14 ENST00000456445.1
four and a half LIM domains 1
chr5_-_115890554 0.14 ENST00000509665.1
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr18_+_66382428 0.14 ENST00000578970.1
ENST00000582371.1
ENST00000584775.1
coiled-coil domain containing 102B
chr10_-_65028817 0.14 ENST00000542921.1
jumonji domain containing 1C
chrX_-_50386648 0.13 ENST00000460112.3
shroom family member 4
chr11_-_67981046 0.13 ENST00000402789.1
ENST00000402185.2
ENST00000458496.1
suppressor of variegation 4-20 homolog 1 (Drosophila)
chr2_+_145425534 0.13 ENST00000432608.1
ENST00000597655.1
ENST00000598659.1
ENST00000600679.1
ENST00000601277.1
ENST00000451027.1
ENST00000445791.1
ENST00000596540.1
ENST00000596230.1
ENST00000594471.1
ENST00000598248.1
ENST00000597469.1
ENST00000431734.1
ENST00000595686.1
testis expressed 41 (non-protein coding)
chr5_-_74162739 0.13 ENST00000513277.1
family with sequence similarity 169, member A
chr11_-_77531858 0.13 ENST00000360355.2
remodeling and spacing factor 1
chr1_+_202431859 0.12 ENST00000391959.3
ENST00000367270.4
protein phosphatase 1, regulatory subunit 12B
chr20_+_58251716 0.12 ENST00000355648.4
phosphatase and actin regulator 3
chr17_-_34890037 0.12 ENST00000589404.1
myosin XIX
chr14_-_69446034 0.12 ENST00000193403.6
actinin, alpha 1
chr2_-_202316169 0.11 ENST00000430254.1
trafficking protein, kinesin binding 2
chr14_+_59100774 0.11 ENST00000556859.1
ENST00000421793.1
dishevelled-binding antagonist of beta-catenin 1
chr6_-_30524951 0.11 ENST00000376621.3
guanine nucleotide binding protein-like 1
chr1_-_116383322 0.11 ENST00000429731.1
nescient helix loop helix 2
chr17_+_7461849 0.10 ENST00000338784.4
tumor necrosis factor (ligand) superfamily, member 13
chr11_-_77531752 0.10 ENST00000440064.2
ENST00000528095.1
remodeling and spacing factor 1
chr17_+_7462103 0.10 ENST00000396545.4
tumor necrosis factor (ligand) superfamily, member 13
chr17_+_7461781 0.10 ENST00000349228.4
tumor necrosis factor (ligand) superfamily, member 13
chr19_+_2785458 0.10 ENST00000307741.6
ENST00000585338.1
thimet oligopeptidase 1
chr8_+_107593198 0.10 ENST00000517686.1
oxidation resistance 1
chr5_+_118691706 0.09 ENST00000415806.2
tumor necrosis factor, alpha-induced protein 8
chr3_-_185655795 0.09 ENST00000342294.4
ENST00000382191.4
ENST00000453386.2
transformer 2 beta homolog (Drosophila)
chr2_+_68962014 0.09 ENST00000467265.1
Rho GTPase activating protein 25
chr6_-_41254403 0.09 ENST00000589614.1
ENST00000334475.6
ENST00000591620.1
ENST00000244709.4
triggering receptor expressed on myeloid cells 1
chr11_+_77532233 0.09 ENST00000525409.1
adipogenesis associated, Mth938 domain containing
chr1_-_205649580 0.09 ENST00000367145.3
solute carrier family 45, member 3
chr16_-_29757272 0.09 ENST00000329410.3
chromosome 16 open reading frame 54
chr1_-_241799232 0.09 ENST00000366553.1
choroideremia-like (Rab escort protein 2)
chr1_-_147245445 0.09 ENST00000430508.1
gap junction protein, alpha 5, 40kDa
chr8_+_11666649 0.08 ENST00000528643.1
ENST00000525777.1
farnesyl-diphosphate farnesyltransferase 1
chr5_+_112227311 0.08 ENST00000391338.1
zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 1
chr9_-_135996537 0.08 ENST00000372050.3
ENST00000372047.3
ral guanine nucleotide dissociation stimulator
chr18_-_21017817 0.08 ENST00000542162.1
ENST00000383233.3
ENST00000582336.1
ENST00000450466.2
ENST00000578520.1
ENST00000399707.1
transmembrane protein 241
chr3_+_158787041 0.08 ENST00000471575.1
ENST00000476809.1
ENST00000485419.1
IQCJ-SCHIP1 readthrough
chr7_+_76091775 0.08 ENST00000442516.1
deltex homolog 2 (Drosophila)
chr12_-_71031185 0.08 ENST00000548122.1
ENST00000551525.1
ENST00000550358.1
protein tyrosine phosphatase, receptor type, B
chr2_+_68961905 0.08 ENST00000295381.3
Rho GTPase activating protein 25
chr6_+_30951487 0.07 ENST00000486149.2
ENST00000376296.3
mucin 21, cell surface associated
chr2_+_68961934 0.07 ENST00000409202.3
Rho GTPase activating protein 25
chr12_-_42878101 0.07 ENST00000552108.1
prickle homolog 1 (Drosophila)
chr10_-_35379524 0.07 ENST00000374751.3
ENST00000374742.1
ENST00000602371.1
cullin 2
chrX_-_100546314 0.07 ENST00000356784.1
TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa
chr17_-_34890617 0.07 ENST00000586886.1
ENST00000585719.1
ENST00000585818.1
myosin XIX
chr14_+_56127960 0.06 ENST00000553624.1
kinectin 1 (kinesin receptor)
chr15_+_30918879 0.06 ENST00000428041.2
Rho GTPase activating protein 11B
chr12_-_51402984 0.06 ENST00000545993.2
solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
chr2_-_204400013 0.06 ENST00000374489.2
ENST00000374488.2
ENST00000308091.4
ENST00000453034.1
ENST00000420371.1
Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
chr2_+_145425573 0.06 ENST00000600064.1
ENST00000597670.1
ENST00000414256.1
ENST00000599187.1
ENST00000451774.1
ENST00000599072.1
ENST00000596589.1
ENST00000597893.1
testis expressed 41 (non-protein coding)
chr1_+_149754227 0.06 ENST00000444948.1
ENST00000369168.4
Fc fragment of IgG, high affinity Ia, receptor (CD64)
chr12_-_54779511 0.06 ENST00000551109.1
ENST00000546970.1
zinc finger protein 385A
chr11_+_76745385 0.06 ENST00000533140.1
ENST00000354301.5
ENST00000528622.1
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6 (core 3 synthase)
chr1_+_26759295 0.06 ENST00000430232.1
dehydrodolichyl diphosphate synthase
chr20_-_18477862 0.06 ENST00000337227.4
retinoblastoma binding protein 9
chr5_-_88120083 0.05 ENST00000509373.1
myocyte enhancer factor 2C
chr2_+_234526272 0.05 ENST00000373450.4
UDP glucuronosyltransferase 1 family, polypeptide A8
chr11_-_77532050 0.05 ENST00000308488.6
remodeling and spacing factor 1
chr5_+_36608280 0.05 ENST00000513646.1
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr17_+_44588877 0.05 ENST00000576629.1
leucine rich repeat containing 37, member A2
chr7_+_23637763 0.05 ENST00000410069.1
coiled-coil domain containing 126
chr17_+_40912764 0.04 ENST00000589683.1
ENST00000588928.1
receptor (G protein-coupled) activity modifying protein 2
chr15_+_96869165 0.04 ENST00000421109.2
nuclear receptor subfamily 2, group F, member 2
chr2_-_203735484 0.04 ENST00000420558.1
ENST00000418208.1
islet cell autoantigen 1,69kDa-like
chr22_-_31364187 0.04 ENST00000215862.4
ENST00000397641.3
MORC family CW-type zinc finger 2
chr16_+_30075463 0.04 ENST00000562168.1
ENST00000569545.1
aldolase A, fructose-bisphosphate
chr1_-_94586651 0.04 ENST00000535735.1
ENST00000370225.3
ATP-binding cassette, sub-family A (ABC1), member 4
chr12_+_6493319 0.04 ENST00000536876.1
lymphotoxin beta receptor (TNFR superfamily, member 3)
chr11_+_77532155 0.04 ENST00000532481.1
ENST00000526415.1
ENST00000393427.2
ENST00000527134.1
ENST00000304716.8
adipogenesis associated, Mth938 domain containing
chr22_+_32439019 0.04 ENST00000266088.4
solute carrier family 5 (sodium/glucose cotransporter), member 1
chr16_-_67753206 0.03 ENST00000268797.7
glucose-fructose oxidoreductase domain containing 2
chr2_-_39664206 0.03 ENST00000484274.1
mitogen-activated protein kinase kinase kinase kinase 3
chrX_-_73511908 0.03 ENST00000455395.1
FTX transcript, XIST regulator (non-protein coding)
chr18_-_53068782 0.03 ENST00000569012.1
transcription factor 4
chr20_+_42136308 0.03 ENST00000434666.1
ENST00000427442.2
ENST00000439769.1
ENST00000418998.1
l(3)mbt-like 1 (Drosophila)
chr11_+_63655987 0.03 ENST00000509502.2
ENST00000512060.1
MAP/microtubule affinity-regulating kinase 2
chr1_-_227505826 0.03 ENST00000334218.5
ENST00000366766.2
ENST00000366764.2
CDC42 binding protein kinase alpha (DMPK-like)
chr5_-_88120151 0.03 ENST00000506716.1
myocyte enhancer factor 2C
chr3_+_172034218 0.03 ENST00000366261.2
Uncharacterized protein
chr7_+_129015671 0.03 ENST00000466993.1
adenosylhomocysteinase-like 2
chr13_+_50589390 0.03 ENST00000360473.4
ENST00000312942.1
potassium channel regulator
chr7_+_129015484 0.03 ENST00000490911.1
adenosylhomocysteinase-like 2
chr17_+_61473104 0.03 ENST00000583016.1
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr10_+_124907638 0.03 ENST00000339992.3
H6 family homeobox 2
chr19_-_52254050 0.02 ENST00000600815.1
formyl peptide receptor 1
chrX_-_110507098 0.02 ENST00000541758.1
calpain 6
chr2_-_202316260 0.02 ENST00000332624.3
trafficking protein, kinesin binding 2
chr8_+_123793633 0.02 ENST00000314393.4
zinc fingers and homeoboxes 2
chr11_+_44069531 0.02 ENST00000378832.1
1-aminocyclopropane-1-carboxylate synthase homolog (Arabidopsis)(non-functional)-like
chr8_+_39972170 0.02 ENST00000521257.1
RP11-359E19.2
chr10_-_101769617 0.01 ENST00000324109.4
ENST00000342239.3
dynamin binding protein
chr7_+_138818490 0.01 ENST00000430935.1
ENST00000495038.1
ENST00000474035.2
ENST00000478836.2
ENST00000464848.1
ENST00000343187.4
tetratricopeptide repeat domain 26
chr11_-_60720002 0.01 ENST00000538739.1
solute carrier family 15 (oligopeptide transporter), member 3
chr8_-_117886955 0.01 ENST00000297338.2
RAD21 homolog (S. pombe)
chr12_-_42877726 0.01 ENST00000548696.1
prickle homolog 1 (Drosophila)
chr3_+_132379154 0.01 ENST00000468022.1
ENST00000473651.1
ENST00000494238.2
ubiquitin-like modifier activating enzyme 5
chr2_+_173600565 0.01 ENST00000397081.3
Rap guanine nucleotide exchange factor (GEF) 4
chr9_+_36572851 0.01 ENST00000298048.2
ENST00000538311.1
ENST00000536987.1
ENST00000545008.1
ENST00000536860.1
ENST00000536329.1
ENST00000541717.1
ENST00000543751.1
maternal embryonic leucine zipper kinase
chr15_+_25200108 0.01 ENST00000577949.1
ENST00000338094.6
ENST00000338327.4
ENST00000579070.1
ENST00000577565.1
SNRPN upstream reading frame protein
small nuclear ribonucleoprotein polypeptide N
chr1_+_152691998 0.01 ENST00000368775.2
chromosome 1 open reading frame 68
chr11_-_72463421 0.01 ENST00000393609.3
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr11_-_119252425 0.01 ENST00000260187.2
ubiquitin specific peptidase 2
chr20_+_57209828 0.01 ENST00000598340.1
HCG1785561; MGC4294 protein; Uncharacterized protein
chr10_-_35379241 0.00 ENST00000374748.1
ENST00000374749.3
cullin 2
chr9_-_13175823 0.00 ENST00000545857.1
multiple PDZ domain protein
chr5_-_146461027 0.00 ENST00000394410.2
ENST00000508267.1
ENST00000504198.1
protein phosphatase 2, regulatory subunit B, beta

Network of associatons between targets according to the STRING database.

First level regulatory network of STAT6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.9 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.2 1.3 GO:0033591 response to L-ascorbic acid(GO:0033591)
0.2 0.7 GO:0042144 vacuole fusion, non-autophagic(GO:0042144)
0.2 0.5 GO:0070429 regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) tolerance induction to lipopolysaccharide(GO:0072573) negative regulation of CD40 signaling pathway(GO:2000349)
0.1 0.6 GO:1904499 glial cell fate determination(GO:0007403) canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324) regulation of chromatin-mediated maintenance of transcription(GO:1904499) positive regulation of chromatin-mediated maintenance of transcription(GO:1904501) regulation of euchromatin binding(GO:1904793)
0.1 0.9 GO:0045229 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.1 1.1 GO:0033183 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.1 0.3 GO:0051714 positive regulation of cytolysis in other organism(GO:0051714)
0.1 0.9 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.1 0.3 GO:0086055 atrial ventricular junction remodeling(GO:0003294) atrial cardiac muscle cell to AV node cell communication by electrical coupling(GO:0086044) bundle of His cell to Purkinje myocyte communication by electrical coupling(GO:0086054) Purkinje myocyte to ventricular cardiac muscle cell communication by electrical coupling(GO:0086055) regulation of Purkinje myocyte action potential(GO:0098906) vasomotion(GO:1990029)
0.1 0.5 GO:0018032 protein amidation(GO:0018032)
0.1 0.6 GO:0006543 glutamine catabolic process(GO:0006543)
0.1 0.3 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.1 0.8 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.1 0.6 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.1 0.2 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 0.5 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.1 0.2 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.1 0.4 GO:0030578 PML body organization(GO:0030578)
0.1 0.2 GO:0044691 tooth eruption(GO:0044691)
0.0 0.1 GO:0098972 dendritic transport of mitochondrion(GO:0098939) anterograde dendritic transport of mitochondrion(GO:0098972)
0.0 0.2 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.5 GO:0048733 sebaceous gland development(GO:0048733)
0.0 0.4 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.0 0.3 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.3 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.0 0.2 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0 0.1 GO:0015770 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.0 0.4 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.8 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.2 GO:0002329 pre-B cell differentiation(GO:0002329)
0.0 0.3 GO:0071313 cellular response to caffeine(GO:0071313)
0.0 0.3 GO:0015866 ADP transport(GO:0015866)
0.0 0.2 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.0 0.1 GO:0006696 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.0 1.0 GO:0060706 cell differentiation involved in embryonic placenta development(GO:0060706)
0.0 0.1 GO:0048619 embryonic hindgut morphogenesis(GO:0048619)
0.0 0.1 GO:0036079 GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
0.0 0.2 GO:0044821 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0 0.1 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.1 GO:2000691 regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.0 0.1 GO:0070945 neutrophil mediated killing of gram-negative bacterium(GO:0070945)
0.0 0.1 GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.0 0.1 GO:0016094 polyprenol biosynthetic process(GO:0016094)
0.0 0.1 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.3 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.6 GO:0003016 respiratory system process(GO:0003016)
0.0 0.1 GO:0003138 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.0 0.1 GO:0070980 biphenyl catabolic process(GO:0070980)
0.0 0.1 GO:0015692 lead ion transport(GO:0015692)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 GO:1990357 terminal web(GO:1990357)
0.1 0.7 GO:0033263 CORVET complex(GO:0033263)
0.1 0.3 GO:0031213 RSF complex(GO:0031213)
0.1 0.8 GO:0005610 laminin-5 complex(GO:0005610)
0.1 0.6 GO:0070369 Scrib-APC-beta-catenin complex(GO:0034750) beta-catenin-TCF7L2 complex(GO:0070369)
0.1 0.2 GO:0005584 collagen type I trimer(GO:0005584)
0.1 0.4 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.1 0.2 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.3 GO:1990425 ryanodine receptor complex(GO:1990425)
0.0 1.3 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.0 0.3 GO:0000798 nuclear cohesin complex(GO:0000798)
0.0 0.8 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.3 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 1.8 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.1 GO:0089701 U2AF(GO:0089701)
0.0 0.9 GO:0001533 cornified envelope(GO:0001533)
0.0 0.3 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.1 GO:0005916 fascia adherens(GO:0005916)
0.0 0.1 GO:0070826 paraferritin complex(GO:0070826)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.1 1.9 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.1 0.3 GO:0086078 gap junction channel activity involved in atrial cardiac muscle cell-AV node cell electrical coupling(GO:0086076) gap junction channel activity involved in bundle of His cell-Purkinje myocyte electrical coupling(GO:0086078) gap junction channel activity involved in Purkinje myocyte-ventricular cardiac muscle cell electrical coupling(GO:0086079)
0.1 0.5 GO:0004598 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.1 0.3 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.1 0.6 GO:0004359 glutaminase activity(GO:0004359)
0.1 0.3 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.1 0.9 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 0.2 GO:0004917 interleukin-7 receptor activity(GO:0004917)
0.0 0.2 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.0 0.5 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 1.3 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 0.1 GO:0015157 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0 0.6 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.1 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.0 0.3 GO:0005347 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.2 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.1 GO:0036080 GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
0.0 0.4 GO:0005283 sodium:amino acid symporter activity(GO:0005283)
0.0 0.1 GO:0047223 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity(GO:0047223)
0.0 0.1 GO:0002094 polyprenyltransferase activity(GO:0002094)
0.0 0.7 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 1.3 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.2 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.1 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 0.1 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.5 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.0 GO:0032093 SAM domain binding(GO:0032093)
0.0 0.1 GO:0015094 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.0 1.3 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.4 GO:0008139 nuclear localization sequence binding(GO:0008139)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 1.9 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.6 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 1.0 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.9 PID IL1 PATHWAY IL1-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.6 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.5 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.3 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.9 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling