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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for TBP

Z-value: 5.18

Motif logo

Transcription factors associated with TBP

Gene Symbol Gene ID Gene Info
ENSG00000112592.8 TATA-box binding protein

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TBPhg19_v2_chr6_+_170863421_170863484-0.561.0e-02Click!

Activity profile of TBP motif

Sorted Z-values of TBP motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_59043166 32.19 ENST00000371225.2
tumor-associated calcium signal transducer 2
chr1_+_153330322 31.77 ENST00000368738.3
S100 calcium binding protein A9
chr16_+_56659687 21.73 ENST00000568293.1
ENST00000330439.6
metallothionein 1E
chr11_+_18287801 20.66 ENST00000532858.1
ENST00000405158.2
serum amyloid A1
chr13_+_43597269 20.02 ENST00000379221.2
DnaJ (Hsp40) homolog, subfamily C, member 15
chr17_-_39780819 19.69 ENST00000311208.8
keratin 17
chr11_+_18287721 19.14 ENST00000356524.4
serum amyloid A1
chr12_-_52845910 18.22 ENST00000252252.3
keratin 6B
chr17_-_39780634 18.14 ENST00000577817.2
keratin 17
chr14_+_75745477 18.07 ENST00000303562.4
ENST00000554617.1
ENST00000554212.1
ENST00000535987.1
ENST00000555242.1
FBJ murine osteosarcoma viral oncogene homolog
chr11_-_18270182 17.93 ENST00000528349.1
ENST00000526900.1
ENST00000529528.1
ENST00000414546.2
ENST00000256733.4
serum amyloid A2
chr17_-_39661849 17.68 ENST00000246635.3
ENST00000336861.3
ENST00000587544.1
ENST00000587435.1
keratin 13
chr12_-_52867569 17.51 ENST00000252250.6
keratin 6C
chr1_-_182360918 16.79 ENST00000339526.4
glutamate-ammonia ligase
chr1_-_153363452 16.62 ENST00000368732.1
ENST00000368733.3
S100 calcium binding protein A8
chr1_+_152881014 16.52 ENST00000368764.3
ENST00000392667.2
involucrin
chr3_+_122044084 16.46 ENST00000264474.3
ENST00000479204.1
cystatin A (stefin A)
chr1_-_182361327 16.01 ENST00000331872.6
ENST00000311223.5
glutamate-ammonia ligase
chr1_+_153003671 15.94 ENST00000307098.4
small proline-rich protein 1B
chr19_-_12912657 15.78 ENST00000301522.2
peroxiredoxin 2
chr1_-_182360498 15.72 ENST00000417584.2
glutamate-ammonia ligase
chr19_-_12912601 15.55 ENST00000334482.5
peroxiredoxin 2
chr8_-_6735451 15.44 ENST00000297439.3
defensin, beta 1
chr1_-_156675564 15.32 ENST00000368220.1
cellular retinoic acid binding protein 2
chr1_-_156675535 15.31 ENST00000368221.1
cellular retinoic acid binding protein 2
chr21_-_28217721 15.24 ENST00000284984.3
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr17_-_39781054 14.10 ENST00000463128.1
keratin 17
chr1_-_156675368 13.85 ENST00000368222.3
cellular retinoic acid binding protein 2
chr9_+_130911723 13.37 ENST00000277480.2
ENST00000373013.2
ENST00000540948.1
lipocalin 2
chr9_+_130911770 12.70 ENST00000372998.1
lipocalin 2
chr1_+_89829610 12.68 ENST00000370456.4
ENST00000535065.1
guanylate binding protein family, member 6
chr19_-_12912688 12.65 ENST00000435703.1
peroxiredoxin 2
chr8_-_124553437 12.22 ENST00000517956.1
ENST00000443022.2
F-box protein 32
chr18_-_61329118 12.03 ENST00000332821.8
ENST00000283752.5
serpin peptidase inhibitor, clade B (ovalbumin), member 3
chr17_-_39661947 11.77 ENST00000590425.1
keratin 13
chr1_-_95007193 11.39 ENST00000370207.4
ENST00000334047.7
coagulation factor III (thromboplastin, tissue factor)
chr20_-_43883197 11.03 ENST00000338380.2
secretory leukocyte peptidase inhibitor
chr17_-_39674668 10.94 ENST00000393981.3
keratin 15
chr19_+_10381769 10.54 ENST00000423829.2
ENST00000588645.1
intercellular adhesion molecule 1
chr1_-_153013588 9.88 ENST00000360379.3
small proline-rich protein 2D
chr1_-_153538011 9.79 ENST00000368707.4
S100 calcium binding protein A2
chr3_+_193853927 9.63 ENST00000232424.3
hes family bHLH transcription factor 1
chr11_-_102651343 8.70 ENST00000279441.4
ENST00000539681.1
matrix metallopeptidase 10 (stromelysin 2)
chr6_-_26216872 8.67 ENST00000244601.3
histone cluster 1, H2bg
chr3_-_111314230 8.49 ENST00000317012.4
zinc finger, BED-type containing 2
chr19_-_6720686 8.41 ENST00000245907.6
complement component 3
chr9_-_33447584 8.37 ENST00000297991.4
aquaporin 3 (Gill blood group)
chr5_-_42811986 8.35 ENST00000511224.1
ENST00000507920.1
ENST00000510965.1
selenoprotein P, plasma, 1
chr1_-_209825674 7.10 ENST00000367030.3
ENST00000356082.4
laminin, beta 3
chr12_+_4385230 7.06 ENST00000536537.1
cyclin D2
chr5_-_42812143 6.87 ENST00000514985.1
selenoprotein P, plasma, 1
chr7_-_41742697 6.73 ENST00000242208.4
inhibin, beta A
chr11_-_102826434 6.58 ENST00000340273.4
ENST00000260302.3
matrix metallopeptidase 13 (collagenase 3)
chr19_+_13049413 6.55 ENST00000316448.5
ENST00000588454.1
calreticulin
chr17_+_80186908 6.50 ENST00000582743.1
ENST00000578684.1
ENST00000577650.1
ENST00000582715.1
solute carrier family 16 (monocarboxylate transporter), member 3
chr1_+_40942887 6.46 ENST00000372706.1
ZFP69 zinc finger protein
chr1_-_117753540 6.43 ENST00000328189.3
ENST00000369458.3
V-set domain containing T cell activation inhibitor 1
chr6_-_26124138 6.40 ENST00000314332.5
ENST00000396984.1
histone cluster 1, H2bc
chrX_-_48931648 6.39 ENST00000376386.3
ENST00000376390.4
PRA1 domain family, member 2
chr3_-_99595037 6.36 ENST00000383694.2
filamin A interacting protein 1-like
chr1_-_153044083 6.31 ENST00000341611.2
small proline-rich protein 2B
chr15_-_41166414 6.28 ENST00000220507.4
ras homolog family member V
chr1_-_27481401 6.20 ENST00000263980.3
solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
chr4_+_74735102 6.15 ENST00000395761.3
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
chr16_-_56701933 6.14 ENST00000568675.1
ENST00000569500.1
ENST00000444837.2
ENST00000379811.3
metallothionein 1G
chr14_+_71108460 6.14 ENST00000256367.2
tetratricopeptide repeat domain 9
chr11_+_65266507 5.98 ENST00000544868.1
metastasis associated lung adenocarcinoma transcript 1 (non-protein coding)
chr19_-_53360853 5.89 ENST00000596559.1
ENST00000594602.1
ENST00000595646.1
ENST00000597924.1
ENST00000396409.4
ENST00000390651.4
ENST00000243639.4
zinc finger protein 28
zinc finger protein 468
chr3_-_99594948 5.88 ENST00000471562.1
ENST00000495625.2
filamin A interacting protein 1-like
chr19_-_53636125 5.67 ENST00000601493.1
ENST00000599261.1
ENST00000597503.1
ENST00000500065.4
ENST00000243643.4
ENST00000594011.1
ENST00000455735.2
ENST00000595193.1
ENST00000448501.1
ENST00000421033.1
ENST00000440291.1
ENST00000595813.1
ENST00000600574.1
ENST00000596051.1
ENST00000601110.1
zinc finger protein 415
chr4_-_110723134 5.60 ENST00000510800.1
ENST00000512148.1
complement factor I
chr15_+_81071684 5.46 ENST00000220244.3
ENST00000394685.3
ENST00000356249.5
KIAA1199
chr16_+_2880369 5.44 ENST00000572863.1
zymogen granule protein 16B
chr17_+_76183398 5.43 ENST00000409257.5
arylformamidase
chr15_+_45722727 5.37 ENST00000396650.2
ENST00000558435.1
ENST00000344300.3
chromosome 15 open reading frame 48
chr3_+_101546827 5.31 ENST00000461724.1
ENST00000483180.1
ENST00000394054.2
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
chr1_+_31885963 5.29 ENST00000373709.3
serine incorporator 2
chr2_+_192543694 5.27 ENST00000435931.1
nucleic acid binding protein 1
chr16_+_82068830 5.22 ENST00000199936.4
hydroxysteroid (17-beta) dehydrogenase 2
chr4_+_74606223 5.21 ENST00000307407.3
ENST00000401931.1
interleukin 8
chr6_+_26217159 5.18 ENST00000303910.2
histone cluster 1, H2ae
chr1_-_89488510 5.16 ENST00000564665.1
ENST00000370481.4
guanylate binding protein 3
chr1_+_161228517 5.16 ENST00000504449.1
Purkinje cell protein 4 like 1
chr19_-_53141584 5.07 ENST00000597161.1
ENST00000596930.1
ENST00000545872.1
ENST00000544146.1
ENST00000536937.1
ENST00000301096.3
zinc finger protein 83
chr4_-_153601136 4.94 ENST00000504064.1
ENST00000304385.3
transmembrane protein 154
chr19_+_49375649 4.93 ENST00000200453.5
protein phosphatase 1, regulatory subunit 15A
chr16_+_2014993 4.74 ENST00000564014.1
small nucleolar RNA host gene 9 (non-protein coding)
chr2_+_169923504 4.72 ENST00000357546.2
dehydrogenase/reductase (SDR family) member 9
chr2_+_192543153 4.71 ENST00000425611.2
nucleic acid binding protein 1
chr21_-_43735628 4.68 ENST00000291525.10
ENST00000518498.1
trefoil factor 3 (intestinal)
chr11_+_63304273 4.62 ENST00000439013.2
ENST00000255688.3
retinoic acid receptor responder (tazarotene induced) 3
chr17_-_48546232 4.62 ENST00000258969.4
chondroadherin
chr8_+_22960426 4.61 ENST00000540813.1
tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
chr20_+_31823792 4.58 ENST00000375413.4
ENST00000354297.4
ENST00000375422.2
BPI fold containing family A, member 1
chrX_-_7895755 4.56 ENST00000444736.1
ENST00000537427.1
ENST00000442940.1
patatin-like phospholipase domain containing 4
chr22_+_39916558 4.55 ENST00000337304.2
ENST00000396680.1
activating transcription factor 4
chr19_-_2050852 4.54 ENST00000541165.1
ENST00000591601.1
MAP kinase interacting serine/threonine kinase 2
chr17_-_48546324 4.53 ENST00000508540.1
chondroadherin
chr13_-_43566301 4.52 ENST00000398762.3
ENST00000313640.7
ENST00000313624.7
epithelial stromal interaction 1 (breast)
chr11_+_43964055 4.48 ENST00000528572.1
chromosome 11 open reading frame 96
chr7_-_92777606 4.41 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
sterile alpha motif domain containing 9-like
chr7_+_142829162 4.38 ENST00000291009.3
prolactin-induced protein
chr1_-_149814478 4.34 ENST00000369161.3
histone cluster 2, H2aa3
chr4_-_57547870 4.24 ENST00000381260.3
ENST00000420433.1
ENST00000554144.1
ENST00000557328.1
HOP homeobox
chr4_+_119200215 4.22 ENST00000602573.1
small nucleolar RNA host gene 8 (non-protein coding)
chr7_+_44836276 4.22 ENST00000451562.1
ENST00000468812.1
ENST00000489459.1
ENST00000355968.6
peptidylprolyl isomerase A (cyclophilin A)
chr4_-_110723194 4.18 ENST00000394635.3
complement factor I
chr1_+_86046433 4.11 ENST00000451137.2
cysteine-rich, angiogenic inducer, 61
chr12_+_56435637 4.11 ENST00000356464.5
ENST00000552361.1
ribosomal protein S26
chr6_+_32940436 4.09 ENST00000395287.1
bromodomain containing 2
chr6_-_133035185 4.08 ENST00000367928.4
vanin 1
chr12_+_130646999 4.08 ENST00000539839.1
ENST00000229030.4
frizzled family receptor 10
chrX_-_7895479 4.06 ENST00000381042.4
patatin-like phospholipase domain containing 4
chr2_+_169923577 4.05 ENST00000432060.2
dehydrogenase/reductase (SDR family) member 9
chr1_+_149822620 4.04 ENST00000369159.2
histone cluster 2, H2aa4
chr4_-_110723335 4.03 ENST00000394634.2
complement factor I
chr6_-_134495992 3.95 ENST00000475719.2
ENST00000367857.5
ENST00000237305.7
serum/glucocorticoid regulated kinase 1
chr1_-_6551720 3.92 ENST00000377728.3
pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr7_-_100026280 3.51 ENST00000360951.4
ENST00000398027.2
ENST00000324725.6
ENST00000472716.1
zinc finger, CW type with PWWP domain 1
chr18_+_34124507 3.51 ENST00000591635.1
formin homology 2 domain containing 3
chr11_-_61735029 3.50 ENST00000526640.1
ferritin, heavy polypeptide 1
chr1_+_144339738 3.43 ENST00000538264.1
Protein LOC642441
chr6_-_26197478 3.42 ENST00000356476.2
histone cluster 1, H3d
chr22_-_19466643 3.40 ENST00000474226.1
ubiquitin fusion degradation 1 like (yeast)
chr4_-_100140331 3.37 ENST00000407820.2
ENST00000394897.1
ENST00000508558.1
ENST00000394899.2
alcohol dehydrogenase 6 (class V)
chr19_+_52839515 3.36 ENST00000403906.3
ENST00000601151.1
zinc finger protein 610
chr12_+_96252706 3.34 ENST00000266735.5
ENST00000553192.1
ENST00000552085.1
small nuclear ribonucleoprotein polypeptide F
chr11_-_61734599 3.29 ENST00000532601.1
ferritin, heavy polypeptide 1
chr16_+_2880157 3.28 ENST00000382280.3
zymogen granule protein 16B
chr16_+_82068873 3.28 ENST00000566213.1
hydroxysteroid (17-beta) dehydrogenase 2
chr6_-_26199499 3.27 ENST00000377831.5
histone cluster 1, H3d
chr17_-_39553844 3.26 ENST00000251645.2
keratin 31
chr10_-_74856608 3.25 ENST00000307116.2
ENST00000373008.2
ENST00000412021.2
ENST00000394890.2
ENST00000263556.3
ENST00000440381.1
prolyl 4-hydroxylase, alpha polypeptide I
chr6_+_43543942 3.24 ENST00000372226.1
ENST00000443535.1
polymerase (DNA directed), eta
chr3_-_197024965 3.21 ENST00000392382.2
discs, large homolog 1 (Drosophila)
chr8_+_75896849 3.21 ENST00000520277.1
cysteine-rich secretory protein LCCL domain containing 1
chr4_-_74853897 3.20 ENST00000296028.3
pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
chr9_+_92219919 3.14 ENST00000252506.6
ENST00000375769.1
growth arrest and DNA-damage-inducible, gamma
chr3_+_40498783 3.08 ENST00000338970.6
ENST00000396203.2
ENST00000416518.1
ribosomal protein L14
chr6_-_26199471 3.04 ENST00000341023.1
histone cluster 1, H2ad
chr19_-_8386238 2.99 ENST00000301457.2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa
chr4_-_100356291 2.98 ENST00000476959.1
ENST00000482593.1
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr11_-_2906979 2.97 ENST00000380725.1
ENST00000313407.6
ENST00000430149.2
ENST00000440480.2
ENST00000414822.3
cyclin-dependent kinase inhibitor 1C (p57, Kip2)
chr17_-_38859996 2.96 ENST00000264651.2
keratin 24
chr1_+_152730499 2.96 ENST00000368773.1
keratinocyte proline-rich protein
chr16_+_2014941 2.95 ENST00000531523.1
small nucleolar RNA host gene 9 (non-protein coding)
chr1_+_37940153 2.94 ENST00000373087.6
zinc finger CCCH-type containing 12A
chrX_+_7137475 2.92 ENST00000217961.4
steroid sulfatase (microsomal), isozyme S
chr1_-_89357179 2.90 ENST00000448623.1
ENST00000418217.1
ENST00000370500.5
general transcription factor IIB
chr20_+_30193083 2.89 ENST00000376112.3
ENST00000376105.3
inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
chr7_-_75401513 2.88 ENST00000005180.4
chemokine (C-C motif) ligand 26
chr12_+_40787194 2.88 ENST00000425730.2
ENST00000454784.4
mucin 19, oligomeric
chr6_+_31802364 2.87 ENST00000375640.3
ENST00000375641.2
chromosome 6 open reading frame 48
chr4_-_159094194 2.86 ENST00000592057.1
ENST00000585682.1
ENST00000393807.5
family with sequence similarity 198, member B
chr19_-_55866061 2.85 ENST00000588572.2
ENST00000593184.1
ENST00000589467.1
cytochrome c oxidase subunit VIb polypeptide 2 (testis)
chr19_+_1026298 2.85 ENST00000263097.4
calponin 2
chr8_+_79503458 2.83 ENST00000518467.1
protein kinase (cAMP-dependent, catalytic) inhibitor alpha
chr2_+_39893043 2.82 ENST00000281961.2
transmembrane protein 178A
chr22_+_29876197 2.81 ENST00000310624.6
neurofilament, heavy polypeptide
chr17_-_48278983 2.77 ENST00000225964.5
collagen, type I, alpha 1
chr15_-_82939157 2.73 ENST00000559949.1
golgin A6 family-like 18
chr9_+_135937365 2.73 ENST00000372080.4
ENST00000351304.7
carboxyl ester lipase
chr19_+_52839490 2.72 ENST00000321287.8
zinc finger protein 610
chr1_+_55446465 2.70 ENST00000371268.3
transmembrane protein 61
chr3_-_197025447 2.69 ENST00000346964.2
ENST00000357674.4
ENST00000314062.3
ENST00000448528.2
ENST00000419553.1
discs, large homolog 1 (Drosophila)
chr7_-_72439997 2.69 ENST00000285805.3
tripartite motif containing 74
chr1_+_145883868 2.68 ENST00000447947.2
G protein-coupled receptor 89C
chr1_-_150552006 2.64 ENST00000307940.3
ENST00000369026.2
myeloid cell leukemia sequence 1 (BCL2-related)
chr5_+_66254698 2.64 ENST00000405643.1
ENST00000407621.1
ENST00000432426.1
microtubule associated serine/threonine kinase family member 4
chr3_-_24536453 2.62 ENST00000453729.2
ENST00000413780.1
thyroid hormone receptor, beta
chr6_-_114292449 2.60 ENST00000519065.1
histone deacetylase 2
chr9_+_124088860 2.58 ENST00000373806.1
gelsolin
chr1_-_228613026 2.57 ENST00000366696.1
histone cluster 3, H3
chr10_+_91087651 2.55 ENST00000371818.4
interferon-induced protein with tetratricopeptide repeats 3
chr11_-_2160611 2.53 ENST00000416167.2
insulin-like growth factor 2 (somatomedin A)
chr22_-_19466454 2.53 ENST00000494054.1
ubiquitin fusion degradation 1 like (yeast)
chr5_+_112196919 2.52 ENST00000505459.1
ENST00000282999.3
ENST00000515463.1
signal recognition particle 19kDa
chr1_-_8086343 2.52 ENST00000474874.1
ENST00000469499.1
ENST00000377482.5
ERBB receptor feedback inhibitor 1
chr1_+_33546714 2.51 ENST00000294517.6
ENST00000358680.3
ENST00000373443.3
ENST00000398167.1
arginine decarboxylase
chr18_-_47018769 2.46 ENST00000583637.1
ENST00000578528.1
ENST00000578532.1
ENST00000580387.1
ENST00000579248.1
ENST00000581373.1
ribosomal protein L17
chr19_-_53238260 2.45 ENST00000453741.2
ENST00000602162.1
ENST00000601643.1
ENST00000596702.1
ENST00000600943.1
ENST00000543227.1
ENST00000540744.1
zinc finger protein 611
chr1_+_17575584 2.43 ENST00000375460.3
peptidyl arginine deiminase, type III
chr6_+_27806319 2.42 ENST00000606613.1
ENST00000396980.3
histone cluster 1, H2bn
chr15_+_49715449 2.40 ENST00000560979.1
fibroblast growth factor 7
chr2_-_151344172 2.37 ENST00000375734.2
ENST00000263895.4
ENST00000454202.1
Rho family GTPase 3
chr19_+_1026566 2.37 ENST00000348419.3
ENST00000565096.2
ENST00000562958.2
ENST00000562075.2
ENST00000607102.1
calponin 2
chr7_+_72742178 2.35 ENST00000442793.1
ENST00000413573.2
ENST00000252037.4
FK506 binding protein 6, 36kDa
chr11_+_128634589 2.34 ENST00000281428.8
Fli-1 proto-oncogene, ETS transcription factor
chr18_+_29598335 2.33 ENST00000217740.3
ring finger protein 125, E3 ubiquitin protein ligase
chr19_-_47164386 2.33 ENST00000391916.2
ENST00000410105.2
dishevelled-binding antagonist of beta-catenin 3
chr14_-_92198403 2.32 ENST00000553329.1
ENST00000256343.3
catsper channel auxiliary subunit beta
chr17_+_79008940 2.31 ENST00000392411.3
ENST00000575989.1
ENST00000321280.7
ENST00000428708.2
ENST00000575712.1
ENST00000575245.1
ENST00000435091.3
ENST00000321300.6
BAI1-associated protein 2
chr10_+_88780049 2.31 ENST00000343959.4
family with sequence similarity 25, member A
chr6_-_30585009 2.28 ENST00000376511.2
protein phosphatase 1, regulatory subunit 10
chr6_-_137539651 2.26 ENST00000543628.1
interferon gamma receptor 1
chr1_-_230850043 2.25 ENST00000366667.4
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr1_+_150245099 2.24 ENST00000369099.3
chromosome 1 open reading frame 54
chr18_-_47018897 2.24 ENST00000418495.1
ribosomal protein L17
chr1_+_24069952 2.23 ENST00000609199.1
transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A)
chr19_+_4769117 2.23 ENST00000540211.1
ENST00000317292.3
ENST00000586721.1
ENST00000592709.1
ENST00000588711.1
ENST00000589639.1
ENST00000591008.1
ENST00000592663.1
ENST00000588758.1
MIR7-3 host gene (non-protein coding)

Network of associatons between targets according to the STRING database.

First level regulatory network of TBP

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
12.1 48.5 GO:0006542 glutamine biosynthetic process(GO:0006542)
10.8 32.3 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
5.2 26.1 GO:0015688 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
4.6 9.1 GO:1900155 regulation of bone trabecula formation(GO:1900154) negative regulation of bone trabecula formation(GO:1900155)
3.9 15.4 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
3.8 11.4 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
3.3 20.0 GO:1902957 negative regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902957)
3.3 16.5 GO:0018262 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
3.2 32.2 GO:0090191 negative regulation of branching involved in ureteric bud morphogenesis(GO:0090191)
3.2 9.6 GO:2000974 auditory receptor cell fate determination(GO:0042668) cell-cell signaling involved in cell fate commitment(GO:0045168) negative regulation of auditory receptor cell differentiation(GO:0045608) regulation of timing of neuron differentiation(GO:0060164) negative regulation of pro-B cell differentiation(GO:2000974)
3.0 12.0 GO:0035425 autocrine signaling(GO:0035425)
2.8 8.4 GO:0001798 positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894)
2.8 44.5 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
2.2 6.7 GO:0060278 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
2.1 2.1 GO:1904666 regulation of ubiquitin protein ligase activity(GO:1904666) positive regulation of ubiquitin protein ligase activity(GO:1904668)
2.0 18.1 GO:0001661 conditioned taste aversion(GO:0001661)
2.0 32.0 GO:0043587 tongue morphogenesis(GO:0043587)
1.8 10.5 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
1.7 5.2 GO:0060323 body morphogenesis(GO:0010171) head morphogenesis(GO:0060323) face morphogenesis(GO:0060325)
1.7 48.8 GO:0051798 positive regulation of hair follicle development(GO:0051798)
1.6 4.9 GO:0060734 regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734)
1.5 6.2 GO:0086092 regulation of the force of heart contraction by cardiac conduction(GO:0086092)
1.5 4.6 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
1.4 8.4 GO:0070295 renal water absorption(GO:0070295)
1.3 1.3 GO:0002085 inhibition of neuroepithelial cell differentiation(GO:0002085)
1.2 40.6 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
1.1 4.6 GO:1900191 biofilm formation(GO:0042710) single-species biofilm formation(GO:0044010) single-species biofilm formation in or on host organism(GO:0044407) regulation of single-species biofilm formation(GO:1900190) negative regulation of single-species biofilm formation(GO:1900191) regulation of single-species biofilm formation in or on host organism(GO:1900228) negative regulation of single-species biofilm formation in or on host organism(GO:1900229)
1.1 4.6 GO:0010430 fatty acid omega-oxidation(GO:0010430)
1.1 16.5 GO:0032119 sequestering of zinc ion(GO:0032119)
1.1 6.5 GO:0002501 peptide antigen assembly with MHC protein complex(GO:0002501)
1.1 6.4 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
1.0 2.9 GO:2000625 regulation of miRNA catabolic process(GO:2000625) positive regulation of miRNA catabolic process(GO:2000627)
1.0 2.9 GO:1904798 positive regulation of core promoter binding(GO:1904798)
1.0 2.9 GO:0010621 negative regulation of transcription by transcription factor localization(GO:0010621)
1.0 1.0 GO:1903413 cellular response to bile acid(GO:1903413)
1.0 41.2 GO:0050716 positive regulation of interleukin-1 secretion(GO:0050716)
0.9 2.8 GO:0033693 neurofilament bundle assembly(GO:0033693)
0.9 6.5 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.9 2.7 GO:0051037 regulation of transcription involved in meiotic cell cycle(GO:0051037)
0.9 5.3 GO:1904219 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.8 27.1 GO:0071294 cellular response to zinc ion(GO:0071294)
0.8 8.8 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.8 15.2 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.8 2.3 GO:0048611 ectodermal digestive tract development(GO:0007439) embryonic ectodermal digestive tract development(GO:0048611)
0.8 3.0 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.7 2.2 GO:0034226 lysine import(GO:0034226) L-lysine import(GO:0061461) L-lysine import into cell(GO:1903410)
0.7 4.2 GO:0044800 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.7 2.1 GO:0015670 carbon dioxide transport(GO:0015670)
0.7 2.8 GO:0044691 tooth eruption(GO:0044691)
0.7 4.1 GO:0003278 apoptotic process involved in heart morphogenesis(GO:0003278)
0.7 1.4 GO:0014016 neuroblast differentiation(GO:0014016)
0.7 4.1 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.7 49.5 GO:0018149 peptide cross-linking(GO:0018149)
0.6 12.2 GO:0014877 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.6 2.5 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.6 1.9 GO:1900390 positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440)
0.6 0.6 GO:0043163 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.5 5.9 GO:1903760 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760)
0.5 1.6 GO:0035284 rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.5 2.6 GO:0008050 female courtship behavior(GO:0008050)
0.5 2.6 GO:0044858 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.5 9.2 GO:0006569 tryptophan catabolic process(GO:0006569) indole-containing compound catabolic process(GO:0042436) indolalkylamine catabolic process(GO:0046218)
0.5 14.0 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.5 2.4 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.5 18.2 GO:0007398 ectoderm development(GO:0007398)
0.5 2.3 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.5 4.6 GO:0002227 innate immune response in mucosa(GO:0002227)
0.4 5.3 GO:1902177 positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902177)
0.4 3.0 GO:0016098 monoterpenoid metabolic process(GO:0016098)
0.4 3.2 GO:0071494 cellular response to UV-C(GO:0071494)
0.4 1.5 GO:0099640 axo-dendritic protein transport(GO:0099640)
0.4 8.1 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.4 0.7 GO:0051040 regulation of calcium-independent cell-cell adhesion(GO:0051040)
0.4 3.9 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.3 1.4 GO:0035106 operant conditioning(GO:0035106)
0.3 1.3 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.3 4.0 GO:0070294 renal sodium ion absorption(GO:0070294)
0.3 2.0 GO:0060437 lung growth(GO:0060437)
0.3 1.0 GO:0060730 regulation of intestinal epithelial structure maintenance(GO:0060730)
0.3 6.5 GO:0003417 growth plate cartilage development(GO:0003417)
0.3 1.9 GO:0060686 negative regulation of prostatic bud formation(GO:0060686)
0.3 10.5 GO:0019731 antibacterial humoral response(GO:0019731)
0.3 1.5 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.3 4.4 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.3 7.1 GO:0071481 cellular response to X-ray(GO:0071481)
0.3 1.4 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.3 2.5 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.3 0.6 GO:0002725 negative regulation of T cell cytokine production(GO:0002725)
0.3 1.4 GO:0010269 response to selenium ion(GO:0010269)
0.3 4.1 GO:2000400 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.3 3.1 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.3 2.3 GO:1905232 cellular response to L-glutamate(GO:1905232)
0.3 6.6 GO:0097286 iron ion import(GO:0097286)
0.3 3.3 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.2 0.2 GO:0071288 cellular response to mercury ion(GO:0071288)
0.2 2.0 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.2 3.0 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.2 15.9 GO:0006953 acute-phase response(GO:0006953)
0.2 6.8 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.2 1.8 GO:0019236 response to pheromone(GO:0019236)
0.2 2.5 GO:0060426 lung vasculature development(GO:0060426)
0.2 0.7 GO:0051097 negative regulation of helicase activity(GO:0051097)
0.2 1.8 GO:0036151 phosphatidylcholine acyl-chain remodeling(GO:0036151)
0.2 6.1 GO:0006706 steroid catabolic process(GO:0006706)
0.2 1.6 GO:0035900 isocitrate metabolic process(GO:0006102) response to isolation stress(GO:0035900)
0.2 10.2 GO:0045103 intermediate filament-based process(GO:0045103)
0.2 7.1 GO:0031581 hemidesmosome assembly(GO:0031581)
0.2 1.9 GO:0000023 maltose metabolic process(GO:0000023)
0.2 2.1 GO:0046689 response to mercury ion(GO:0046689)
0.2 1.0 GO:0014807 regulation of somitogenesis(GO:0014807)
0.2 0.6 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
0.2 0.6 GO:0061485 memory T cell proliferation(GO:0061485)
0.2 3.4 GO:0006069 ethanol oxidation(GO:0006069)
0.2 8.7 GO:0019433 triglyceride catabolic process(GO:0019433)
0.2 5.5 GO:0048240 sperm capacitation(GO:0048240)
0.2 4.5 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.2 3.7 GO:0034587 piRNA metabolic process(GO:0034587)
0.2 1.5 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.2 2.3 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.2 14.3 GO:0001895 retina homeostasis(GO:0001895)
0.2 7.2 GO:0015813 L-glutamate transport(GO:0015813)
0.2 0.8 GO:0007056 spindle assembly involved in female meiosis(GO:0007056)
0.2 0.6 GO:0090131 mesenchyme migration(GO:0090131)
0.2 2.0 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.2 1.5 GO:0070307 lens fiber cell development(GO:0070307)
0.1 0.4 GO:0090214 spongiotrophoblast layer developmental growth(GO:0090214)
0.1 1.7 GO:1904628 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.1 4.6 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.1 0.3 GO:0021530 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.1 2.8 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 3.5 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.1 1.0 GO:0010727 negative regulation of hydrogen peroxide metabolic process(GO:0010727)
0.1 0.7 GO:0034124 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124)
0.1 0.8 GO:1990539 fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
0.1 0.7 GO:0042483 negative regulation of odontogenesis(GO:0042483)
0.1 1.8 GO:0010818 T cell chemotaxis(GO:0010818)
0.1 11.2 GO:0006958 complement activation, classical pathway(GO:0006958)
0.1 0.3 GO:0006579 amino-acid betaine catabolic process(GO:0006579)
0.1 0.5 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.1 0.3 GO:0051866 general adaptation syndrome(GO:0051866)
0.1 2.3 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.1 11.5 GO:0009301 snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.1 1.7 GO:0030913 fusion of sperm to egg plasma membrane(GO:0007342) paranodal junction assembly(GO:0030913)
0.1 0.6 GO:0051684 maintenance of Golgi location(GO:0051684)
0.1 0.6 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.1 1.3 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.1 0.8 GO:0070162 adiponectin secretion(GO:0070162) regulation of adiponectin secretion(GO:0070163)
0.1 4.1 GO:0033119 negative regulation of RNA splicing(GO:0033119)
0.1 3.3 GO:0008334 histone mRNA metabolic process(GO:0008334)
0.1 0.7 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.1 1.9 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 2.6 GO:0032460 negative regulation of protein oligomerization(GO:0032460)
0.1 2.3 GO:0035855 megakaryocyte development(GO:0035855)
0.1 6.6 GO:0071349 interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
0.1 0.3 GO:0039533 regulation of MDA-5 signaling pathway(GO:0039533) positive regulation of MDA-5 signaling pathway(GO:1900245)
0.1 0.9 GO:0048260 positive regulation of receptor-mediated endocytosis(GO:0048260)
0.1 0.2 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.1 2.8 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.1 13.2 GO:0071346 cellular response to interferon-gamma(GO:0071346)
0.1 8.2 GO:0022617 extracellular matrix disassembly(GO:0022617)
0.1 1.7 GO:1901687 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.1 2.0 GO:0044381 glucose import in response to insulin stimulus(GO:0044381)
0.0 1.2 GO:0002347 response to tumor cell(GO:0002347)
0.0 1.1 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.0 0.3 GO:1903301 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.0 0.5 GO:0021853 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0 1.0 GO:0061436 regulation of water loss via skin(GO:0033561) establishment of skin barrier(GO:0061436)
0.0 0.4 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 0.9 GO:0045665 negative regulation of neuron differentiation(GO:0045665)
0.0 1.9 GO:0021591 ventricular system development(GO:0021591)
0.0 0.7 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.0 0.7 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 2.6 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 1.0 GO:0036315 cellular response to sterol(GO:0036315)
0.0 0.4 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.2 GO:0055014 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.0 1.5 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 5.5 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.9 GO:0001502 cartilage condensation(GO:0001502)
0.0 1.2 GO:0010667 negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.0 3.3 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.2 GO:0061365 positive regulation of triglyceride lipase activity(GO:0061365)
0.0 0.7 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.5 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.8 GO:0010212 response to ionizing radiation(GO:0010212)
0.0 0.2 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.0 1.2 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.4 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 2.7 GO:0006903 vesicle targeting(GO:0006903)
0.0 1.6 GO:0032781 positive regulation of ATPase activity(GO:0032781)
0.0 0.6 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.4 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.7 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 0.9 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.0 1.6 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.5 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.7 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.0 1.3 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.0 4.1 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.8 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.3 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.1 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0 0.8 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.8 GO:0034113 heterotypic cell-cell adhesion(GO:0034113)
0.0 0.1 GO:0006600 creatine metabolic process(GO:0006600)
0.0 0.3 GO:0009142 nucleoside triphosphate biosynthetic process(GO:0009142)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
3.9 15.4 GO:1990742 microvesicle(GO:1990742)
2.2 6.7 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
2.0 18.1 GO:0035976 AP1 complex(GO:0035976)
1.5 39.2 GO:0097386 glial cell projection(GO:0097386)
1.4 47.8 GO:0071682 endocytic vesicle lumen(GO:0071682)
1.2 10.0 GO:0070876 SOSS complex(GO:0070876)
0.9 2.8 GO:0005584 collagen type I trimer(GO:0005584)
0.9 2.8 GO:0036457 keratohyalin granule(GO:0036457)
0.9 65.6 GO:0001533 cornified envelope(GO:0001533)
0.9 7.1 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.8 3.3 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.8 4.6 GO:1990037 Lewy body core(GO:1990037)
0.6 7.1 GO:0005610 laminin-5 complex(GO:0005610)
0.6 2.3 GO:1990745 EARP complex(GO:1990745)
0.6 34.3 GO:0009925 basal plasma membrane(GO:0009925)
0.5 92.3 GO:0005882 intermediate filament(GO:0005882)
0.5 51.3 GO:0035580 specific granule lumen(GO:0035580)
0.5 2.0 GO:0016939 kinesin II complex(GO:0016939)
0.5 5.9 GO:0043219 lateral loop(GO:0043219)
0.4 1.3 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.4 2.9 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.4 3.3 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.4 17.0 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.3 11.4 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.3 2.0 GO:0032593 insulin-responsive compartment(GO:0032593)
0.3 5.0 GO:0030061 mitochondrial crista(GO:0030061)
0.3 4.1 GO:0035686 sperm fibrous sheath(GO:0035686)
0.3 1.6 GO:0016235 aggresome(GO:0016235)
0.3 2.3 GO:0036128 CatSper complex(GO:0036128)
0.3 2.3 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.2 2.9 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.2 4.9 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.2 16.9 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.2 2.5 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.2 1.4 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.2 0.6 GO:0070702 inner mucus layer(GO:0070702) outer mucus layer(GO:0070703)
0.2 2.6 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.2 6.2 GO:0090533 cation-transporting ATPase complex(GO:0090533)
0.2 0.7 GO:0008043 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.2 2.6 GO:0030478 actin cap(GO:0030478)
0.2 0.7 GO:0044216 host(GO:0018995) host cell(GO:0043657) other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.2 10.5 GO:0001772 immunological synapse(GO:0001772)
0.2 2.3 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.2 19.4 GO:0035578 azurophil granule lumen(GO:0035578)
0.2 1.8 GO:0042382 paraspeckles(GO:0042382)
0.2 1.4 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 1.9 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.1 12.9 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 1.5 GO:0001939 female pronucleus(GO:0001939)
0.1 3.1 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 32.4 GO:0034774 secretory granule lumen(GO:0034774)
0.1 0.6 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.1 0.6 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.1 0.9 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1 1.2 GO:0071986 Ragulator complex(GO:0071986)
0.1 0.8 GO:0097208 alveolar lamellar body(GO:0097208)
0.1 9.0 GO:0035577 azurophil granule membrane(GO:0035577)
0.1 8.0 GO:0005811 lipid particle(GO:0005811)
0.1 19.5 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.1 2.6 GO:0016580 Sin3 complex(GO:0016580)
0.1 2.1 GO:0002080 acrosomal membrane(GO:0002080)
0.1 8.5 GO:0005604 basement membrane(GO:0005604)
0.1 1.1 GO:0097225 sperm midpiece(GO:0097225)
0.1 3.5 GO:0005865 striated muscle thin filament(GO:0005865)
0.1 1.3 GO:0001891 phagocytic cup(GO:0001891)
0.1 3.6 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 1.7 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 4.3 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.8 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 1.8 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 3.2 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.5 GO:0097470 ribbon synapse(GO:0097470)
0.0 4.1 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 6.8 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 2.0 GO:1904115 axon cytoplasm(GO:1904115)
0.0 5.6 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.6 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.2 GO:0005579 membrane attack complex(GO:0005579)
0.0 4.3 GO:0005769 early endosome(GO:0005769)
0.0 0.9 GO:0005774 vacuolar membrane(GO:0005774)
0.0 4.8 GO:0016605 PML body(GO:0016605)
0.0 0.7 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 12.8 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 16.6 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 0.6 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 5.5 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 2.7 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.3 GO:0071437 invadopodium(GO:0071437)
0.0 1.5 GO:0005796 Golgi lumen(GO:0005796)
0.0 3.4 GO:0009986 cell surface(GO:0009986)
0.0 0.1 GO:0005916 fascia adherens(GO:0005916)
0.0 0.4 GO:0002102 podosome(GO:0002102)
0.0 0.6 GO:0014704 intercalated disc(GO:0014704)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
12.1 48.5 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
6.9 48.4 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
6.5 51.9 GO:0042289 MHC class II protein binding(GO:0042289)
5.1 15.4 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
4.2 41.8 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
2.1 10.4 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
2.1 6.2 GO:0086040 sodium:proton antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086040)
2.0 49.4 GO:0019841 retinol binding(GO:0019841)
1.7 8.4 GO:0015254 glycerol channel activity(GO:0015254)
1.5 12.1 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
1.4 8.7 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
1.1 6.7 GO:0070699 type II activin receptor binding(GO:0070699)
1.1 58.2 GO:0042056 chemoattractant activity(GO:0042056)
1.0 14.0 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.7 2.9 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.7 4.2 GO:0045569 TRAIL binding(GO:0045569)
0.7 4.1 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.7 6.1 GO:0001849 complement component C1q binding(GO:0001849)
0.6 1.8 GO:0017130 poly(C) RNA binding(GO:0017130)
0.6 1.8 GO:0016503 pheromone receptor activity(GO:0016503)
0.6 4.2 GO:0046790 virion binding(GO:0046790)
0.6 6.6 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.5 1.6 GO:0051538 3 iron, 4 sulfur cluster binding(GO:0051538)
0.5 6.5 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.5 4.9 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.5 2.4 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.5 5.9 GO:0097016 L27 domain binding(GO:0097016)
0.4 4.4 GO:0019864 IgG binding(GO:0019864)
0.4 1.3 GO:0070697 activin receptor binding(GO:0070697)
0.4 1.5 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.4 2.3 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.4 3.3 GO:0019798 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.3 1.4 GO:0004995 tachykinin receptor activity(GO:0004995)
0.3 2.7 GO:0004771 sterol esterase activity(GO:0004771)
0.3 1.4 GO:0033265 acetylcholinesterase activity(GO:0003990) choline binding(GO:0033265)
0.3 2.6 GO:0051434 BH3 domain binding(GO:0051434)
0.3 2.1 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.3 1.5 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.3 1.5 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.3 5.3 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.3 69.5 GO:0002020 protease binding(GO:0002020)
0.3 0.8 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
0.3 18.1 GO:0070412 R-SMAD binding(GO:0070412)
0.2 2.7 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.2 1.7 GO:0035473 lipase binding(GO:0035473)
0.2 1.9 GO:0032450 alpha-1,4-glucosidase activity(GO:0004558) maltose alpha-glucosidase activity(GO:0032450)
0.2 2.3 GO:0070097 delta-catenin binding(GO:0070097)
0.2 1.9 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.2 2.5 GO:0008312 7S RNA binding(GO:0008312)
0.2 4.5 GO:0010857 calcium-dependent protein serine/threonine kinase activity(GO:0009931) calcium-dependent protein kinase activity(GO:0010857)
0.2 1.8 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.2 2.4 GO:0015250 water channel activity(GO:0015250)
0.2 1.4 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.2 27.5 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.2 2.6 GO:0045159 myosin II binding(GO:0045159)
0.2 1.5 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.2 4.1 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.2 4.7 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.2 2.9 GO:0070628 proteasome binding(GO:0070628)
0.1 3.1 GO:0008494 translation activator activity(GO:0008494)
0.1 2.2 GO:0070324 thyroid hormone binding(GO:0070324)
0.1 6.8 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 3.0 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 4.5 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 4.0 GO:0017081 chloride channel regulator activity(GO:0017081)
0.1 0.5 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.1 1.2 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.1 5.9 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.1 2.2 GO:0031701 angiotensin receptor binding(GO:0031701) type 1 angiotensin receptor binding(GO:0031702)
0.1 0.9 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.1 0.8 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
0.1 1.0 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.1 2.0 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.1 2.9 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.1 0.8 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 0.3 GO:0047150 betaine-homocysteine S-methyltransferase activity(GO:0047150)
0.1 2.2 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.1 2.8 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.1 5.2 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 5.0 GO:0004623 phospholipase A2 activity(GO:0004623)
0.1 12.9 GO:0051087 chaperone binding(GO:0051087)
0.1 0.6 GO:0002114 interleukin-33 receptor activity(GO:0002114)
0.1 0.7 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.1 3.2 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 1.9 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 17.9 GO:0004866 endopeptidase inhibitor activity(GO:0004866)
0.1 0.6 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.1 2.9 GO:0017025 TBP-class protein binding(GO:0017025)
0.1 25.8 GO:0030674 protein binding, bridging(GO:0030674)
0.1 8.0 GO:0001618 virus receptor activity(GO:0001618)
0.1 0.8 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 1.5 GO:0008392 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.1 6.6 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 0.3 GO:0030492 hemoglobin binding(GO:0030492)
0.1 2.0 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.1 3.7 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 1.9 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 0.8 GO:0017091 AU-rich element binding(GO:0017091)
0.0 2.0 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 20.2 GO:0003924 GTPase activity(GO:0003924)
0.0 1.1 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 6.9 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.0 1.5 GO:0005109 frizzled binding(GO:0005109)
0.0 0.9 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.9 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 2.6 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.3 GO:0004331 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 0.7 GO:0004568 chitinase activity(GO:0004568)
0.0 2.1 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 36.3 GO:0005198 structural molecule activity(GO:0005198)
0.0 1.7 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.9 GO:0005313 L-glutamate transmembrane transporter activity(GO:0005313) acidic amino acid transmembrane transporter activity(GO:0015172)
0.0 4.9 GO:0019905 syntaxin binding(GO:0019905)
0.0 0.5 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.0 0.7 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.4 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.6 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.2 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.3 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 2.1 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.7 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 1.5 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 0.1 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0 4.1 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.7 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.5 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.4 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.1 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.3 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.3 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 1.5 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 1.0 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.1 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
0.0 3.1 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.0 0.6 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 1.0 GO:0070888 E-box binding(GO:0070888)
0.0 0.3 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.1 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.3 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.1 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.1 GO:0017018 myosin phosphatase activity(GO:0017018)
0.0 1.4 GO:0016782 transferase activity, transferring sulfur-containing groups(GO:0016782)
0.0 1.1 GO:0004860 protein kinase inhibitor activity(GO:0004860)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 88.2 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.6 18.1 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.4 73.4 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.4 7.1 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.3 21.9 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.3 2.3 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.2 7.1 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.2 9.6 PID ALK1 PATHWAY ALK1 signaling events
0.2 66.2 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.2 9.1 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.2 4.9 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.2 4.1 PID WNT SIGNALING PATHWAY Wnt signaling network
0.2 5.9 PID IL23 PATHWAY IL23-mediated signaling events
0.1 12.2 PID FOXO PATHWAY FoxO family signaling
0.1 5.4 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.1 9.8 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 12.5 PID IL4 2PATHWAY IL4-mediated signaling events
0.1 0.6 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.1 7.7 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.1 4.6 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 4.9 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 4.2 PID TRAIL PATHWAY TRAIL signaling pathway
0.1 5.9 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.1 7.2 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 1.1 NABA COLLAGENS Genes encoding collagen proteins
0.1 4.6 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.1 2.0 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.1 4.9 PID BMP PATHWAY BMP receptor signaling
0.1 2.6 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.1 2.1 PID IL6 7 PATHWAY IL6-mediated signaling events
0.1 3.7 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 0.3 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 3.1 PID IL12 2PATHWAY IL12-mediated signaling events
0.1 1.7 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.1 1.6 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 4.6 PID CMYB PATHWAY C-MYB transcription factor network
0.0 1.7 ST GAQ PATHWAY G alpha q Pathway
0.0 1.4 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 2.0 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 2.0 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 1.5 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 2.6 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.0 0.6 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.7 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.3 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.6 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 3.5 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 41.8 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
1.2 39.8 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
1.0 15.4 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.8 4.2 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.8 18.1 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.7 11.1 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.7 10.7 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.7 22.2 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.7 6.7 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.5 15.8 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.4 9.2 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.4 7.9 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.3 6.5 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.3 6.2 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.3 12.3 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.3 16.8 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.3 31.1 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.2 12.4 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.2 5.9 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.2 3.3 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.2 2.8 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.2 3.9 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.2 3.0 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.1 4.3 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 2.9 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 1.4 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.1 0.6 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.1 0.8 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 6.9 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.1 4.9 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.1 1.8 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.1 0.9 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.1 3.3 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 3.8 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.1 3.9 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 2.9 REACTOME RNA POL II PRE TRANSCRIPTION EVENTS Genes involved in RNA Polymerase II Pre-transcription Events
0.1 1.9 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 12.1 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.1 3.5 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1 1.6 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 1.4 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 2.6 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 1.2 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 1.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0 7.0 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 0.4 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 2.4 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 1.7 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 2.6 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 1.5 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.6 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 15.5 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.0 2.5 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 3.6 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.7 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 2.7 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 1.1 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.5 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 2.0 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.2 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.7 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events