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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for TBX15_MGA

Z-value: 0.47

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Transcription factors associated with TBX15_MGA

Gene Symbol Gene ID Gene Info
TBX15
ENSG00000092607.9 T-box transcription factor 15
MGA
ENSG00000174197.12 MAX dimerization protein MGA

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MGAhg19_v2_chr15_+_41952591_419526720.473.6e-02Click!
TBX15hg19_v2_chr1_-_119530428_119530572-0.262.7e-01Click!

Activity profile of TBX15_MGA motif

Sorted Z-values of TBX15_MGA motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_39216344 1.97 ENST00000391418.2
KRTAP2-3
keratin associated protein 2-3
chr11_+_117947782 1.79 ENST00000522307.1
ENST00000523251.1
ENST00000437212.3
ENST00000522824.1
ENST00000522151.1
TMPRSS4
transmembrane protease, serine 4
chr20_+_44098346 1.27 ENST00000372676.3
WFDC2
WAP four-disulfide core domain 2
chr11_-_119599794 1.26 ENST00000264025.3
PVRL1
poliovirus receptor-related 1 (herpesvirus entry mediator C)
chr20_+_44098385 1.25 ENST00000217425.5
ENST00000339946.3
WFDC2
WAP four-disulfide core domain 2
chr6_-_31619892 1.19 ENST00000454165.1
ENST00000428326.1
ENST00000452994.1
BAG6
BCL2-associated athanogene 6
chr6_-_31620095 1.16 ENST00000424176.1
ENST00000456622.1
BAG6
BCL2-associated athanogene 6
chr11_+_117947724 1.05 ENST00000534111.1
TMPRSS4
transmembrane protease, serine 4
chrX_+_56259316 1.04 ENST00000468660.1
KLF8
Kruppel-like factor 8
chr22_-_31688381 1.03 ENST00000487265.2
PIK3IP1
phosphoinositide-3-kinase interacting protein 1
chr6_-_31619742 1.02 ENST00000433828.1
ENST00000456286.1
BAG6
BCL2-associated athanogene 6
chr6_-_31619697 0.99 ENST00000434444.1
BAG6
BCL2-associated athanogene 6
chr14_-_65569244 0.99 ENST00000557277.1
ENST00000556892.1
MAX
MYC associated factor X
chr4_-_102268708 0.96 ENST00000525819.1
PPP3CA
protein phosphatase 3, catalytic subunit, alpha isozyme
chr19_+_39279838 0.95 ENST00000314980.4
LGALS7B
lectin, galactoside-binding, soluble, 7B
chr18_-_59561417 0.93 ENST00000591306.1
RNF152
ring finger protein 152
chr3_-_197024394 0.92 ENST00000434148.1
ENST00000412364.2
ENST00000436682.1
ENST00000456699.2
ENST00000392380.2
DLG1
discs, large homolog 1 (Drosophila)
chr6_+_36646435 0.90 ENST00000244741.5
ENST00000405375.1
ENST00000373711.2
CDKN1A
cyclin-dependent kinase inhibitor 1A (p21, Cip1)
chr21_+_30503282 0.88 ENST00000399925.1
MAP3K7CL
MAP3K7 C-terminal like
chr21_+_30502806 0.87 ENST00000399928.1
ENST00000399926.1
MAP3K7CL
MAP3K7 C-terminal like
chr1_+_33219592 0.84 ENST00000373481.3
KIAA1522
KIAA1522
chr1_-_226374373 0.79 ENST00000366812.5
ACBD3
acyl-CoA binding domain containing 3
chr11_+_18477369 0.78 ENST00000396213.3
ENST00000280706.2
LDHAL6A
lactate dehydrogenase A-like 6A
chr14_+_95078714 0.77 ENST00000393078.3
ENST00000393080.4
ENST00000467132.1
SERPINA3
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
chr11_-_119993979 0.77 ENST00000524816.3
ENST00000525327.1
TRIM29
tripartite motif containing 29
chr1_-_153029980 0.77 ENST00000392653.2
SPRR2A
small proline-rich protein 2A
chr22_-_31688431 0.77 ENST00000402249.3
ENST00000443175.1
ENST00000215912.5
ENST00000441972.1
PIK3IP1
phosphoinositide-3-kinase interacting protein 1
chr4_-_146859623 0.76 ENST00000379448.4
ENST00000513320.1
ZNF827
zinc finger protein 827
chr20_+_1115821 0.73 ENST00000435720.1
PSMF1
proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
chrX_+_99899180 0.72 ENST00000373004.3
SRPX2
sushi-repeat containing protein, X-linked 2
chr18_+_47088401 0.71 ENST00000261292.4
ENST00000427224.2
ENST00000580036.1
LIPG
lipase, endothelial
chr5_-_49737184 0.71 ENST00000508934.1
ENST00000303221.5
EMB
embigin
chr21_-_42879909 0.71 ENST00000458356.1
ENST00000398585.3
ENST00000424093.1
TMPRSS2
transmembrane protease, serine 2
chrX_+_102862834 0.68 ENST00000372627.5
ENST00000243286.3
TCEAL3
transcription elongation factor A (SII)-like 3
chr1_+_38022513 0.67 ENST00000296218.7
DNALI1
dynein, axonemal, light intermediate chain 1
chr9_+_34990219 0.67 ENST00000541010.1
ENST00000454002.2
ENST00000545841.1
DNAJB5
DnaJ (Hsp40) homolog, subfamily B, member 5
chr3_+_107364769 0.66 ENST00000449271.1
ENST00000425868.1
ENST00000449213.1
BBX
bobby sox homolog (Drosophila)
chr12_-_26278030 0.63 ENST00000242728.4
BHLHE41
basic helix-loop-helix family, member e41
chr5_+_125800836 0.62 ENST00000511134.1
GRAMD3
GRAM domain containing 3
chr11_-_85779971 0.61 ENST00000393346.3
PICALM
phosphatidylinositol binding clathrin assembly protein
chr5_-_124080203 0.60 ENST00000504926.1
ZNF608
zinc finger protein 608
chr4_-_102268484 0.59 ENST00000394853.4
PPP3CA
protein phosphatase 3, catalytic subunit, alpha isozyme
chr1_-_230561475 0.59 ENST00000391860.1
PGBD5
piggyBac transposable element derived 5
chr7_-_105319536 0.58 ENST00000477775.1
ATXN7L1
ataxin 7-like 1
chr1_+_38022572 0.58 ENST00000541606.1
DNALI1
dynein, axonemal, light intermediate chain 1
chr5_-_74807418 0.58 ENST00000405807.4
ENST00000261415.7
COL4A3BP
collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
chr8_+_22435762 0.57 ENST00000456545.1
PDLIM2
PDZ and LIM domain 2 (mystique)
chrX_-_100914781 0.56 ENST00000431597.1
ENST00000458024.1
ENST00000413506.1
ENST00000440675.1
ENST00000328766.5
ENST00000356824.4
ARMCX2
armadillo repeat containing, X-linked 2
chr11_+_93754513 0.56 ENST00000315765.9
HEPHL1
hephaestin-like 1
chrX_+_69642881 0.55 ENST00000453994.2
ENST00000536730.1
ENST00000538649.1
ENST00000374382.3
GDPD2
glycerophosphodiester phosphodiesterase domain containing 2
chr8_-_99954788 0.55 ENST00000523601.1
STK3
serine/threonine kinase 3
chr3_-_93747425 0.55 ENST00000315099.2
STX19
syntaxin 19
chr8_-_49834299 0.54 ENST00000396822.1
SNAI2
snail family zinc finger 2
chr6_+_7541808 0.53 ENST00000379802.3
DSP
desmoplakin
chr1_-_153066998 0.52 ENST00000368750.3
SPRR2E
small proline-rich protein 2E
chr21_-_42880075 0.52 ENST00000332149.5
TMPRSS2
transmembrane protease, serine 2
chr20_-_1309809 0.52 ENST00000360779.3
SDCBP2
syndecan binding protein (syntenin) 2
chr8_+_102504651 0.52 ENST00000251808.3
ENST00000521085.1
GRHL2
grainyhead-like 2 (Drosophila)
chr13_-_46543805 0.52 ENST00000378921.2
ZC3H13
zinc finger CCCH-type containing 13
chr11_+_10772847 0.51 ENST00000524523.1
CTR9
CTR9, Paf1/RNA polymerase II complex component
chr10_+_45406627 0.50 ENST00000389583.4
TMEM72
transmembrane protein 72
chrX_+_15808569 0.50 ENST00000380308.3
ENST00000307771.7
ZRSR2
zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2
chr8_-_49833978 0.50 ENST00000020945.1
SNAI2
snail family zinc finger 2
chr11_+_46402297 0.49 ENST00000405308.2
MDK
midkine (neurite growth-promoting factor 2)
chr6_-_13487784 0.49 ENST00000379287.3
GFOD1
glucose-fructose oxidoreductase domain containing 1
chr1_-_205744205 0.48 ENST00000446390.2
RAB7L1
RAB7, member RAS oncogene family-like 1
chr3_+_127770455 0.48 ENST00000464451.1
SEC61A1
Sec61 alpha 1 subunit (S. cerevisiae)
chr1_+_28586006 0.48 ENST00000253063.3
SESN2
sestrin 2
chr17_+_79031415 0.47 ENST00000572073.1
ENST00000573677.1
BAIAP2
BAI1-associated protein 2
chr2_-_26101314 0.47 ENST00000336112.4
ENST00000272341.4
ASXL2
additional sex combs like 2 (Drosophila)
chr13_-_48575376 0.47 ENST00000434484.1
SUCLA2
succinate-CoA ligase, ADP-forming, beta subunit
chr2_+_219081817 0.47 ENST00000315717.5
ENST00000420104.1
ENST00000295685.10
ARPC2
actin related protein 2/3 complex, subunit 2, 34kDa
chr2_+_61108771 0.46 ENST00000394479.3
REL
v-rel avian reticuloendotheliosis viral oncogene homolog
chr12_-_57634475 0.46 ENST00000393825.1
NDUFA4L2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
chrX_+_107334983 0.45 ENST00000457035.1
ENST00000545696.1
ATG4A
autophagy related 4A, cysteine peptidase
chr14_+_85994943 0.45 ENST00000553678.1
RP11-497E19.2
Uncharacterized protein
chr4_-_146859787 0.45 ENST00000508784.1
ZNF827
zinc finger protein 827
chr14_+_90864504 0.44 ENST00000544280.2
CALM1
calmodulin 1 (phosphorylase kinase, delta)
chr1_-_153044083 0.44 ENST00000341611.2
SPRR2B
small proline-rich protein 2B
chr6_+_7541845 0.44 ENST00000418664.2
DSP
desmoplakin
chr13_-_99667960 0.44 ENST00000448493.2
DOCK9
dedicator of cytokinesis 9
chr1_+_145507587 0.43 ENST00000330165.8
ENST00000369307.3
RBM8A
RNA binding motif protein 8A
chr3_+_107364683 0.43 ENST00000413213.1
BBX
bobby sox homolog (Drosophila)
chr19_+_46531127 0.43 ENST00000601033.1
CTC-344H19.4
CTC-344H19.4
chr10_+_24544249 0.43 ENST00000430453.2
KIAA1217
KIAA1217
chr19_-_11689752 0.42 ENST00000592659.1
ENST00000592828.1
ENST00000218758.5
ENST00000412435.2
ACP5
acid phosphatase 5, tartrate resistant
chr1_-_113258090 0.42 ENST00000309276.6
PPM1J
protein phosphatase, Mg2+/Mn2+ dependent, 1J
chr10_-_126432821 0.42 ENST00000280780.6
FAM53B
family with sequence similarity 53, member B
chr6_+_45390222 0.42 ENST00000359524.5
RUNX2
runt-related transcription factor 2
chr15_+_41913690 0.42 ENST00000563576.1
MGA
MGA, MAX dimerization protein
chr18_-_30050395 0.41 ENST00000269209.6
ENST00000399218.4
GAREM
GRB2 associated, regulator of MAPK1
chr11_+_71846764 0.41 ENST00000456237.1
ENST00000442948.2
ENST00000546166.1
FOLR3
folate receptor 3 (gamma)
chr8_+_102504979 0.40 ENST00000395927.1
GRHL2
grainyhead-like 2 (Drosophila)
chr1_+_150254936 0.40 ENST00000447007.1
ENST00000369095.1
ENST00000369094.1
C1orf51
chromosome 1 open reading frame 51
chr10_+_111765562 0.39 ENST00000360162.3
ADD3
adducin 3 (gamma)
chr9_+_127023704 0.39 ENST00000373596.1
ENST00000425237.1
NEK6
NIMA-related kinase 6
chr6_-_31620149 0.39 ENST00000435080.1
ENST00000375976.4
ENST00000441054.1
BAG6
BCL2-associated athanogene 6
chr12_-_49351228 0.38 ENST00000541959.1
ENST00000447318.2
ARF3
ADP-ribosylation factor 3
chr10_+_47746929 0.38 ENST00000340243.6
ENST00000374277.5
ENST00000449464.2
ENST00000538825.1
ENST00000335083.5
ANXA8L2
AL603965.1
annexin A8-like 2
Protein LOC100996760
chr3_-_99833333 0.38 ENST00000354552.3
ENST00000331335.5
ENST00000398326.2
FILIP1L
filamin A interacting protein 1-like
chr11_+_86511549 0.37 ENST00000533902.2
PRSS23
protease, serine, 23
chr11_-_119993734 0.37 ENST00000533302.1
TRIM29
tripartite motif containing 29
chr6_+_43739697 0.37 ENST00000230480.6
VEGFA
vascular endothelial growth factor A
chr12_-_8815404 0.36 ENST00000359478.2
ENST00000396549.2
MFAP5
microfibrillar associated protein 5
chr3_-_197024965 0.36 ENST00000392382.2
DLG1
discs, large homolog 1 (Drosophila)
chr1_-_113257905 0.36 ENST00000464951.1
PPM1J
protein phosphatase, Mg2+/Mn2+ dependent, 1J
chr16_-_28550320 0.36 ENST00000395641.2
NUPR1
nuclear protein, transcriptional regulator, 1
chr9_+_71986182 0.35 ENST00000303068.7
FAM189A2
family with sequence similarity 189, member A2
chr2_-_230786032 0.35 ENST00000428959.1
TRIP12
thyroid hormone receptor interactor 12
chr17_-_34122596 0.34 ENST00000250144.8
MMP28
matrix metallopeptidase 28
chr3_+_10857885 0.34 ENST00000254488.2
ENST00000454147.1
SLC6A11
solute carrier family 6 (neurotransmitter transporter), member 11
chr19_-_44405941 0.34 ENST00000587128.1
RP11-15A1.3
RP11-15A1.3
chr4_+_160188889 0.33 ENST00000264431.4
RAPGEF2
Rap guanine nucleotide exchange factor (GEF) 2
chr5_-_132112907 0.33 ENST00000458488.2
SEPT8
septin 8
chr2_+_169926047 0.33 ENST00000428522.1
ENST00000450153.1
ENST00000421653.1
DHRS9
dehydrogenase/reductase (SDR family) member 9
chr3_-_120169828 0.33 ENST00000424703.2
ENST00000469005.1
FSTL1
follistatin-like 1
chr6_-_10419871 0.32 ENST00000319516.4
TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr19_+_13135731 0.32 ENST00000587260.1
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr12_-_8815215 0.32 ENST00000544889.1
ENST00000543369.1
MFAP5
microfibrillar associated protein 5
chr2_-_230786378 0.32 ENST00000430954.1
TRIP12
thyroid hormone receptor interactor 12
chr16_+_69139467 0.31 ENST00000569188.1
HAS3
hyaluronan synthase 3
chr1_+_35734616 0.31 ENST00000441447.1
ZMYM4
zinc finger, MYM-type 4
chr17_-_1619568 0.31 ENST00000571595.1
MIR22HG
MIR22 host gene (non-protein coding)
chr4_-_152682129 0.31 ENST00000512306.1
ENST00000508611.1
ENST00000515812.1
ENST00000263985.6
PET112
PET112 homolog (yeast)
chr9_-_73029540 0.31 ENST00000377126.2
KLF9
Kruppel-like factor 9
chrX_+_123095546 0.31 ENST00000371157.3
ENST00000371145.3
ENST00000371144.3
STAG2
stromal antigen 2
chr10_+_98592674 0.31 ENST00000356016.3
ENST00000371097.4
LCOR
ligand dependent nuclear receptor corepressor
chr2_-_31637560 0.31 ENST00000379416.3
XDH
xanthine dehydrogenase
chr11_+_86511569 0.31 ENST00000441050.1
PRSS23
protease, serine, 23
chr5_-_132112921 0.30 ENST00000378721.4
ENST00000378701.1
SEPT8
septin 8
chr19_-_39390212 0.30 ENST00000437828.1
SIRT2
sirtuin 2
chr17_-_1619491 0.30 ENST00000570416.1
ENST00000575626.1
ENST00000610106.1
ENST00000608198.1
ENST00000609442.1
ENST00000334146.3
ENST00000576489.1
ENST00000608245.1
ENST00000609398.1
ENST00000608913.1
ENST00000574016.1
ENST00000571091.1
ENST00000573127.1
ENST00000609990.1
ENST00000576749.1
MIR22HG
MIR22 host gene (non-protein coding)
chr16_+_2588012 0.30 ENST00000354836.5
ENST00000389224.3
PDPK1
3-phosphoinositide dependent protein kinase-1
chr16_+_2587998 0.30 ENST00000441549.3
ENST00000268673.7
PDPK1
3-phosphoinositide dependent protein kinase-1
chr12_-_8815299 0.29 ENST00000535336.1
MFAP5
microfibrillar associated protein 5
chr19_-_39390350 0.29 ENST00000447739.1
ENST00000358931.5
ENST00000407552.1
SIRT2
sirtuin 2
chr19_-_36001286 0.29 ENST00000602679.1
ENST00000492341.2
ENST00000472252.2
ENST00000602781.1
ENST00000402589.2
ENST00000458071.1
ENST00000436012.1
ENST00000443640.1
ENST00000450261.1
ENST00000467637.1
ENST00000480502.1
ENST00000474928.1
ENST00000414866.2
ENST00000392206.2
ENST00000488892.1
DMKN
dermokine
chr12_-_96793142 0.29 ENST00000552262.1
ENST00000551816.1
ENST00000552496.1
CDK17
cyclin-dependent kinase 17
chr3_+_41236325 0.29 ENST00000426215.1
ENST00000405570.1
CTNNB1
catenin (cadherin-associated protein), beta 1, 88kDa
chr19_-_51527467 0.29 ENST00000593681.1
KLK11
kallikrein-related peptidase 11
chr7_+_107220899 0.29 ENST00000379117.2
ENST00000473124.1
BCAP29
B-cell receptor-associated protein 29
chr14_+_67291158 0.28 ENST00000555456.1
GPHN
gephyrin
chr8_+_144821557 0.28 ENST00000534398.1
FAM83H-AS1
FAM83H antisense RNA 1 (head to head)
chr17_+_35849937 0.28 ENST00000394389.4
DUSP14
dual specificity phosphatase 14
chr18_-_45457192 0.28 ENST00000586514.1
ENST00000591214.1
ENST00000589877.1
SMAD2
SMAD family member 2
chr12_+_56473939 0.28 ENST00000450146.2
ERBB3
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
chr3_-_69370095 0.28 ENST00000473029.1
FRMD4B
FERM domain containing 4B
chr9_+_124461603 0.27 ENST00000373782.3
DAB2IP
DAB2 interacting protein
chr12_-_48152428 0.27 ENST00000449771.2
ENST00000395358.3
RAPGEF3
Rap guanine nucleotide exchange factor (GEF) 3
chr2_-_160473114 0.27 ENST00000392783.2
BAZ2B
bromodomain adjacent to zinc finger domain, 2B
chr3_+_38206975 0.27 ENST00000446845.1
ENST00000311806.3
OXSR1
oxidative stress responsive 1
chr12_-_13529642 0.27 ENST00000318426.2
C12orf36
chromosome 12 open reading frame 36
chr12_+_53400176 0.27 ENST00000551002.1
ENST00000420463.3
ENST00000416762.3
ENST00000549481.1
ENST00000552490.1
EIF4B
eukaryotic translation initiation factor 4B
chr20_+_35169885 0.27 ENST00000279022.2
ENST00000346786.2
MYL9
myosin, light chain 9, regulatory
chr9_+_116111794 0.27 ENST00000374183.4
BSPRY
B-box and SPRY domain containing
chr2_-_216003127 0.26 ENST00000412081.1
ENST00000272895.7
ABCA12
ATP-binding cassette, sub-family A (ABC1), member 12
chr8_+_95653840 0.26 ENST00000520385.1
ESRP1
epithelial splicing regulatory protein 1
chrX_+_21959108 0.26 ENST00000457085.1
SMS
spermine synthase
chr13_-_52027134 0.26 ENST00000311234.4
ENST00000425000.1
ENST00000463928.1
ENST00000442263.3
ENST00000398119.2
INTS6
integrator complex subunit 6
chr1_+_27561104 0.26 ENST00000361771.3
WDTC1
WD and tetratricopeptide repeats 1
chr4_+_57371509 0.26 ENST00000360096.2
ARL9
ADP-ribosylation factor-like 9
chr17_-_74533734 0.26 ENST00000589342.1
CYGB
cytoglobin
chr20_+_44509857 0.26 ENST00000372523.1
ENST00000372520.1
ZSWIM1
zinc finger, SWIM-type containing 1
chr12_-_8815477 0.26 ENST00000433590.2
MFAP5
microfibrillar associated protein 5
chr6_-_160166218 0.25 ENST00000537657.1
SOD2
superoxide dismutase 2, mitochondrial
chr7_+_70229899 0.25 ENST00000443672.1
AUTS2
autism susceptibility candidate 2
chrX_+_47050798 0.25 ENST00000412206.1
ENST00000427561.1
UBA1
ubiquitin-like modifier activating enzyme 1
chr4_+_146403912 0.25 ENST00000507367.1
ENST00000394092.2
ENST00000515385.1
SMAD1
SMAD family member 1
chr12_-_120554534 0.25 ENST00000538903.1
ENST00000534951.1
RAB35
RAB35, member RAS oncogene family
chr17_+_26662679 0.24 ENST00000578158.1
TNFAIP1
tumor necrosis factor, alpha-induced protein 1 (endothelial)
chr19_+_13135790 0.24 ENST00000358552.3
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr11_+_71846748 0.24 ENST00000445078.2
FOLR3
folate receptor 3 (gamma)
chr14_-_82000140 0.24 ENST00000555824.1
ENST00000557372.1
ENST00000336735.4
SEL1L
sel-1 suppressor of lin-12-like (C. elegans)
chr13_+_76378357 0.24 ENST00000489941.2
ENST00000525373.1
LMO7
LIM domain 7
chr2_+_61108650 0.24 ENST00000295025.8
REL
v-rel avian reticuloendotheliosis viral oncogene homolog
chr4_-_186732048 0.24 ENST00000448662.2
ENST00000439049.1
ENST00000420158.1
ENST00000431808.1
ENST00000319471.9
SORBS2
sorbin and SH3 domain containing 2
chrX_+_105936982 0.24 ENST00000418562.1
RNF128
ring finger protein 128, E3 ubiquitin protein ligase
chr12_-_85306562 0.24 ENST00000551612.1
ENST00000450363.3
ENST00000552192.1
SLC6A15
solute carrier family 6 (neutral amino acid transporter), member 15
chr13_+_38923959 0.24 ENST00000379649.1
ENST00000239878.4
ENST00000437952.1
ENST00000379641.1
UFM1
ubiquitin-fold modifier 1
chr19_-_12833361 0.24 ENST00000592287.1
TNPO2
transportin 2
chr21_+_27107672 0.24 ENST00000400075.3
GABPA
GA binding protein transcription factor, alpha subunit 60kDa
chr3_+_50211240 0.24 ENST00000420831.1
SEMA3F
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr22_+_40441456 0.23 ENST00000402203.1
TNRC6B
trinucleotide repeat containing 6B
chr7_-_143956815 0.23 ENST00000493325.1
OR2A7
olfactory receptor, family 2, subfamily A, member 7
chr7_-_27135591 0.23 ENST00000343060.4
ENST00000355633.5
HOXA1
homeobox A1
chr11_-_65429891 0.23 ENST00000527874.1
RELA
v-rel avian reticuloendotheliosis viral oncogene homolog A
chr4_-_102268628 0.23 ENST00000323055.6
ENST00000512215.1
ENST00000394854.3
PPP3CA
protein phosphatase 3, catalytic subunit, alpha isozyme
chr5_+_74807886 0.23 ENST00000514296.1
POLK
polymerase (DNA directed) kappa
chr9_+_104296243 0.23 ENST00000466817.1
RNF20
ring finger protein 20, E3 ubiquitin protein ligase
chr9_-_128003606 0.23 ENST00000324460.6
HSPA5
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
chr2_-_27718052 0.23 ENST00000264703.3
FNDC4
fibronectin type III domain containing 4
chrX_-_132549506 0.22 ENST00000370828.3
GPC4
glypican 4
chr2_-_208030886 0.22 ENST00000426163.1
KLF7
Kruppel-like factor 7 (ubiquitous)
chr6_+_30295036 0.22 ENST00000376659.5
ENST00000428555.1
TRIM39
tripartite motif containing 39
chr6_+_7107999 0.22 ENST00000491191.1
ENST00000379938.2
ENST00000471433.1
RREB1
ras responsive element binding protein 1
chr12_-_85306594 0.22 ENST00000266682.5
SLC6A15
solute carrier family 6 (neutral amino acid transporter), member 15
chr4_+_144354644 0.22 ENST00000512843.1
GAB1
GRB2-associated binding protein 1
chr15_+_63481668 0.22 ENST00000321437.4
ENST00000559006.1
ENST00000448330.2
RAB8B
RAB8B, member RAS oncogene family
chr3_+_183899770 0.22 ENST00000442686.1
AP2M1
adaptor-related protein complex 2, mu 1 subunit
chr14_+_55033815 0.21 ENST00000554335.1
SAMD4A
sterile alpha motif domain containing 4A

Network of associatons between targets according to the STRING database.

First level regulatory network of TBX15_MGA

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 4.7 GO:1904379 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.4 1.8 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
0.4 2.1 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.3 1.0 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.2 0.8 GO:0035627 ceramide transport(GO:0035627)
0.2 0.6 GO:0061433 cellular response to caloric restriction(GO:0061433) negative regulation of oligodendrocyte progenitor proliferation(GO:0070446)
0.2 0.7 GO:0010983 positive regulation of high-density lipoprotein particle clearance(GO:0010983)
0.2 0.7 GO:0006781 succinyl-CoA pathway(GO:0006781)
0.2 0.9 GO:0060574 intestinal epithelial cell maturation(GO:0060574)
0.1 0.7 GO:1904504 regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
0.1 0.9 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.1 1.3 GO:1903764 regulation of potassium ion export across plasma membrane(GO:1903764)
0.1 0.5 GO:2001160 regulation of histone H3-K79 methylation(GO:2001160) positive regulation of histone H3-K79 methylation(GO:2001162)
0.1 0.4 GO:1903570 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.1 0.7 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.1 0.6 GO:0030807 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.1 0.4 GO:0006597 spermine biosynthetic process(GO:0006597)
0.1 0.7 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.1 0.4 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.1 1.3 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.1 1.0 GO:0071896 protein localization to adherens junction(GO:0071896)
0.1 0.3 GO:0018315 molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.1 0.3 GO:2000681 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.1 0.6 GO:1902962 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.1 0.5 GO:2000670 positive regulation of dendritic cell apoptotic process(GO:2000670)
0.1 0.8 GO:1901315 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.1 0.5 GO:0039019 pronephric nephron development(GO:0039019)
0.1 0.3 GO:0046379 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.1 0.3 GO:0046110 xanthine metabolic process(GO:0046110)
0.1 0.2 GO:0006117 acetaldehyde metabolic process(GO:0006117)
0.1 0.2 GO:0021589 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
0.1 0.4 GO:1900224 positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
0.1 0.3 GO:1904501 glial cell fate determination(GO:0007403) canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324) regulation of chromatin-mediated maintenance of transcription(GO:1904499) positive regulation of chromatin-mediated maintenance of transcription(GO:1904501) regulation of euchromatin binding(GO:1904793)
0.1 0.5 GO:2001166 regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.1 0.5 GO:1903575 cornified envelope assembly(GO:1903575)
0.1 0.5 GO:0051697 protein delipidation(GO:0051697)
0.1 0.3 GO:0021623 optic cup structural organization(GO:0003409) oculomotor nerve morphogenesis(GO:0021622) oculomotor nerve formation(GO:0021623)
0.1 0.3 GO:0098582 innate vocalization behavior(GO:0098582)
0.1 0.2 GO:0061536 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.1 0.4 GO:0030421 defecation(GO:0030421)
0.1 0.9 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.1 0.5 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.1 0.3 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.1 0.7 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.1 0.2 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.1 0.5 GO:1905232 cellular response to L-glutamate(GO:1905232)
0.1 0.2 GO:0035522 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.1 0.2 GO:0031247 actin rod assembly(GO:0031247)
0.1 0.7 GO:0002051 osteoblast fate commitment(GO:0002051)
0.1 0.3 GO:0003069 age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
0.1 0.3 GO:0019470 4-hydroxyproline catabolic process(GO:0019470)
0.1 0.3 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.1 0.2 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
0.0 0.2 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.0 0.3 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.0 0.2 GO:0021603 cranial nerve formation(GO:0021603)
0.0 0.3 GO:0051414 response to cortisol(GO:0051414)
0.0 0.1 GO:1901340 negative regulation of store-operated calcium channel activity(GO:1901340)
0.0 0.8 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.3 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.0 0.5 GO:0035524 proline transmembrane transport(GO:0035524)
0.0 0.3 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 0.1 GO:0001543 ovarian follicle rupture(GO:0001543)
0.0 0.2 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.0 0.1 GO:0060532 bronchus cartilage development(GO:0060532) lung smooth muscle development(GO:0061145)
0.0 0.3 GO:2000490 negative regulation of hepatic stellate cell activation(GO:2000490)
0.0 0.2 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.4 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.2 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.0 0.2 GO:0044855 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.0 0.6 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.2 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.0 0.1 GO:0021827 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836)
0.0 0.2 GO:0097475 motor neuron migration(GO:0097475)
0.0 0.1 GO:1903824 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208) negative regulation of single strand break repair(GO:1903517) negative regulation of beta-galactosidase activity(GO:1903770) telomere single strand break repair(GO:1903823) negative regulation of telomere single strand break repair(GO:1903824)
0.0 0.1 GO:0040040 thermosensory behavior(GO:0040040)
0.0 0.3 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.1 GO:0033861 negative regulation of NAD(P)H oxidase activity(GO:0033861)
0.0 0.4 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.0 0.1 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.0 0.1 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.0 0.3 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.8 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.6 GO:0090527 actin filament reorganization(GO:0090527)
0.0 0.5 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.0 0.6 GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.0 0.1 GO:0002384 hepatic immune response(GO:0002384)
0.0 0.2 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.0 0.1 GO:0048294 negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.0 0.2 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.2 GO:0035290 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) neural crest cell migration involved in autonomic nervous system development(GO:1901166)
0.0 0.1 GO:0000915 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.0 1.2 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 0.3 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 0.1 GO:0021834 chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration(GO:0021834)
0.0 0.1 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
0.0 0.5 GO:0031629 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.0 0.2 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.0 0.7 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.4 GO:0015884 folic acid transport(GO:0015884)
0.0 0.3 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 0.1 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.0 0.2 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.0 1.6 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.1 GO:1904721 negative regulation of mRNA cleavage(GO:0031438) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.0 0.1 GO:0060067 chemoattraction of serotonergic neuron axon(GO:0036517) cervix development(GO:0060067) planar cell polarity pathway involved in outflow tract morphogenesis(GO:0061347) planar cell polarity pathway involved in ventricular septum morphogenesis(GO:0061348) planar cell polarity pathway involved in cardiac right atrium morphogenesis(GO:0061349) planar cell polarity pathway involved in cardiac muscle tissue morphogenesis(GO:0061350) planar cell polarity pathway involved in pericardium morphogenesis(GO:0061354) chemoattraction of axon(GO:0061642) negative regulation of cell proliferation in midbrain(GO:1904934) planar cell polarity pathway involved in midbrain dopaminergic neuron differentiation(GO:1904955)
0.0 0.2 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.1 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.0 0.1 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 0.2 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.0 0.2 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 0.1 GO:0051461 positive regulation of corticotropin secretion(GO:0051461)
0.0 0.0 GO:1990641 response to iron ion starvation(GO:1990641)
0.0 0.5 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.0 0.1 GO:0008204 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.0 0.1 GO:2000317 negative regulation of T-helper 17 type immune response(GO:2000317) negative regulation of T-helper 17 cell differentiation(GO:2000320)
0.0 0.2 GO:1902416 positive regulation of mRNA binding(GO:1902416)
0.0 0.6 GO:0006825 copper ion transport(GO:0006825)
0.0 0.1 GO:0072752 cellular response to rapamycin(GO:0072752)
0.0 0.3 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.1 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.0 0.1 GO:0032439 endosome localization(GO:0032439)
0.0 0.1 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.4 GO:2000059 negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000059)
0.0 0.4 GO:0060211 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.0 0.1 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.0 0.1 GO:0051121 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.1 GO:0010645 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
0.0 0.2 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 1.4 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.1 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.0 0.4 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0 0.2 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.1 GO:1904636 response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
0.0 0.2 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.1 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.0 0.3 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.0 0.1 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0 0.2 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.0 0.2 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.0 0.1 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.0 0.1 GO:0097101 arterial endothelial cell fate commitment(GO:0060844) blood vessel endothelial cell fate commitment(GO:0060846) endothelial cell fate specification(GO:0060847) blood vessel lumenization(GO:0072554) blood vessel endothelial cell fate specification(GO:0097101) positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0 0.1 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.0 0.2 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.0 0.0 GO:0090678 metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936)
0.0 2.1 GO:0031424 keratinization(GO:0031424)
0.0 0.1 GO:0051096 positive regulation of helicase activity(GO:0051096)
0.0 0.1 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.1 GO:0048341 paraxial mesoderm formation(GO:0048341)
0.0 0.1 GO:0044351 macropinocytosis(GO:0044351)
0.0 0.2 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.1 GO:0090344 negative regulation of cell aging(GO:0090344)
0.0 0.1 GO:0055118 intracellular sequestering of iron ion(GO:0006880) negative regulation of cardiac muscle contraction(GO:0055118) sequestering of iron ion(GO:0097577)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.2 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.0 0.1 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 4.7 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.3 0.9 GO:0070557 PCNA-p21 complex(GO:0070557)
0.2 2.0 GO:0005955 calcineurin complex(GO:0005955)
0.2 0.5 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.1 1.8 GO:0043219 lateral loop(GO:0043219)
0.1 0.3 GO:0036117 hyaluranon cable(GO:0036117)
0.1 0.6 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.1 0.3 GO:1990032 parallel fiber(GO:1990032)
0.1 0.2 GO:0035525 NF-kappaB p50/p65 complex(GO:0035525)
0.1 0.5 GO:0089701 U2AF(GO:0089701)
0.1 0.7 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 1.3 GO:0005916 fascia adherens(GO:0005916)
0.1 0.4 GO:0032444 activin responsive factor complex(GO:0032444)
0.1 0.5 GO:0033503 HULC complex(GO:0033503)
0.1 0.2 GO:0031213 RSF complex(GO:0031213)
0.0 0.2 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 1.2 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.5 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.3 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.3 GO:0097209 epidermal lamellar body(GO:0097209)
0.0 0.2 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.5 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.7 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.0 0.2 GO:0035339 SPOTS complex(GO:0035339)
0.0 0.5 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.2 GO:0031415 NatA complex(GO:0031415)
0.0 1.4 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.1 GO:0043614 multi-eIF complex(GO:0043614) translation preinitiation complex(GO:0070993) glial limiting end-foot(GO:0097451)
0.0 1.6 GO:0001533 cornified envelope(GO:0001533)
0.0 0.2 GO:1990357 terminal web(GO:1990357)
0.0 1.9 GO:0045095 keratin filament(GO:0045095)
0.0 0.3 GO:0030057 desmosome(GO:0030057)
0.0 0.1 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.0 0.7 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.2 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.1 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.6 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.2 GO:0051286 cell tip(GO:0051286)
0.0 0.1 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.0 0.4 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.2 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 1.2 GO:0030286 dynein complex(GO:0030286)
0.0 0.4 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.1 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 0.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 1.1 GO:0016235 aggresome(GO:0016235)
0.0 0.1 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.2 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 0.1 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.0 0.1 GO:1902560 GMP reductase complex(GO:1902560)
0.0 0.2 GO:0030478 actin cap(GO:0030478)
0.0 0.2 GO:0042383 sarcolemma(GO:0042383)
0.0 0.2 GO:0045179 apical cortex(GO:0045179)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.4 2.5 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.3 0.9 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.2 0.7 GO:0004676 3-phosphoinositide-dependent protein kinase activity(GO:0004676)
0.2 0.6 GO:0046970 NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.2 4.3 GO:0015643 toxic substance binding(GO:0015643)
0.2 0.5 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.1 0.4 GO:0016768 spermine synthase activity(GO:0016768)
0.1 1.9 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 0.7 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.1 0.3 GO:0003842 1-pyrroline-5-carboxylate dehydrogenase activity(GO:0003842)
0.1 1.3 GO:0097016 L27 domain binding(GO:0097016)
0.1 0.6 GO:0097001 ceramide binding(GO:0097001)
0.1 0.3 GO:0061599 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.1 1.0 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.1 0.6 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.1 0.8 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.1 0.6 GO:0043426 MRF binding(GO:0043426)
0.1 0.5 GO:0070728 leucine binding(GO:0070728)
0.1 0.3 GO:0034040 lipid-transporting ATPase activity(GO:0034040)
0.1 0.3 GO:0047888 fatty acid peroxidase activity(GO:0047888)
0.1 0.3 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 1.1 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 0.4 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 0.5 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.1 1.3 GO:0045504 dynein heavy chain binding(GO:0045504)
0.1 0.3 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.1 0.7 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.2 GO:0034057 RNA strand-exchange activity(GO:0034057)
0.0 0.2 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.0 0.6 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 1.0 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.6 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.5 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 4.1 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.2 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.3 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.3 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.2 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 1.6 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 1.6 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.6 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 1.0 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.5 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.1 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
0.0 1.1 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.4 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 0.1 GO:0003883 CTP synthase activity(GO:0003883)
0.0 0.7 GO:0070628 proteasome binding(GO:0070628)
0.0 0.2 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.3 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.2 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.0 0.3 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.2 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.0 0.2 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.3 GO:0047035 alcohol dehydrogenase (NAD) activity(GO:0004022) testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 0.2 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.1 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.1 GO:0004310 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.0 0.1 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.0 0.1 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.3 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.1 GO:1902379 receptor tyrosine kinase-like orphan receptor binding(GO:0005115) chemoattractant activity involved in axon guidance(GO:1902379)
0.0 0.1 GO:0051120 hepoxilin A3 synthase activity(GO:0051120)
0.0 0.3 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 1.0 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 0.5 GO:0043022 ribosome binding(GO:0043022)
0.0 0.4 GO:0005542 folic acid binding(GO:0005542)
0.0 0.1 GO:0004882 androgen receptor activity(GO:0004882)
0.0 0.1 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.0 0.2 GO:0046790 virion binding(GO:0046790)
0.0 0.8 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 0.2 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.1 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 0.4 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.2 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.4 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.2 GO:0045159 myosin II binding(GO:0045159)
0.0 0.4 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.1 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.3 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.6 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.0 GO:0071633 dihydroceramidase activity(GO:0071633)
0.0 0.3 GO:0008494 translation activator activity(GO:0008494)
0.0 0.0 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
0.0 0.6 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.5 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.1 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.4 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.2 GO:0005283 sodium:amino acid symporter activity(GO:0005283)
0.0 0.0 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.0 0.7 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.7 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.7 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.2 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.1 GO:0003920 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.0 0.2 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.2 GO:0017049 GTP-Rho binding(GO:0017049)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 1.3 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.9 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 1.6 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 2.8 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.0 1.1 PID MYC PATHWAY C-MYC pathway
0.0 0.7 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 1.5 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.6 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.4 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 1.2 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.6 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 1.3 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 1.2 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.9 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.4 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.2 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.2 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.3 PID HNF3A PATHWAY FOXA1 transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 1.5 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 1.0 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.9 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 2.1 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.4 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.2 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.0 0.5 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.0 0.7 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.7 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 0.7 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.7 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 0.7 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.5 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 1.9 REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION Genes involved in Cyclin E associated events during G1/S transition
0.0 0.9 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.4 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.3 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.3 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.6 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.7 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.6 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.4 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.7 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.3 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.4 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing