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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for TBX2

Z-value: 0.37

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Transcription factors associated with TBX2

Gene Symbol Gene ID Gene Info
TBX2
ENSG00000121068.9 T-box transcription factor 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TBX2hg19_v2_chr17_+_59477233_594772630.512.1e-02Click!

Activity profile of TBX2 motif

Sorted Z-values of TBX2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_15165854 0.74 ENST00000395936.1
ENST00000395938.2
PMP22
peripheral myelin protein 22
chr8_-_27457494 0.63 ENST00000521770.1
CLU
clusterin
chr10_-_14596140 0.61 ENST00000496330.1
FAM107B
family with sequence similarity 107, member B
chr5_+_137514403 0.58 ENST00000513276.1
KIF20A
kinesin family member 20A
chr17_-_19648916 0.56 ENST00000444455.1
ENST00000439102.2
ALDH3A1
aldehyde dehydrogenase 3 family, member A1
chr11_+_61522844 0.56 ENST00000265460.5
MYRF
myelin regulatory factor
chr17_-_15165825 0.54 ENST00000426385.3
PMP22
peripheral myelin protein 22
chrY_+_2709527 0.52 ENST00000250784.8
RPS4Y1
ribosomal protein S4, Y-linked 1
chr3_+_160117062 0.52 ENST00000497311.1
SMC4
structural maintenance of chromosomes 4
chr8_-_19459993 0.51 ENST00000454498.2
ENST00000520003.1
CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr2_-_175870085 0.50 ENST00000409156.3
CHN1
chimerin 1
chr12_+_57853918 0.50 ENST00000532291.1
ENST00000543426.1
ENST00000228682.2
ENST00000546141.1
GLI1
GLI family zinc finger 1
chr15_-_52030293 0.49 ENST00000560491.1
ENST00000267838.3
LYSMD2
LysM, putative peptidoglycan-binding, domain containing 2
chrY_+_2709906 0.49 ENST00000430575.1
RPS4Y1
ribosomal protein S4, Y-linked 1
chr9_-_96717654 0.48 ENST00000253968.6
BARX1
BARX homeobox 1
chr17_-_60005329 0.47 ENST00000251334.6
INTS2
integrator complex subunit 2
chr11_-_28129656 0.46 ENST00000263181.6
KIF18A
kinesin family member 18A
chr12_-_52761262 0.45 ENST00000257901.3
KRT85
keratin 85
chr12_+_47617284 0.45 ENST00000549630.1
ENST00000551777.1
PCED1B
PC-esterase domain containing 1B
chrX_-_119693745 0.44 ENST00000371323.2
CUL4B
cullin 4B
chr12_+_65672423 0.44 ENST00000355192.3
ENST00000308259.5
ENST00000540804.1
ENST00000535664.1
ENST00000541189.1
MSRB3
methionine sulfoxide reductase B3
chr2_-_169769787 0.39 ENST00000451987.1
SPC25
SPC25, NDC80 kinetochore complex component
chr5_-_64858944 0.39 ENST00000508421.1
ENST00000510693.1
ENST00000514814.1
ENST00000515497.1
ENST00000396679.1
CENPK
centromere protein K
chr2_-_175869936 0.38 ENST00000409900.3
CHN1
chimerin 1
chr14_-_55658323 0.38 ENST00000554067.1
ENST00000247191.2
DLGAP5
discs, large (Drosophila) homolog-associated protein 5
chr17_-_60005365 0.37 ENST00000444766.3
INTS2
integrator complex subunit 2
chr10_+_54074033 0.36 ENST00000373970.3
DKK1
dickkopf WNT signaling pathway inhibitor 1
chr8_-_124428569 0.36 ENST00000521903.1
ATAD2
ATPase family, AAA domain containing 2
chr19_-_51875894 0.36 ENST00000600427.1
ENST00000595217.1
ENST00000221978.5
NKG7
natural killer cell group 7 sequence
chr17_-_19648683 0.36 ENST00000573368.1
ENST00000457500.2
ALDH3A1
aldehyde dehydrogenase 3 family, member A1
chr9_+_90112117 0.35 ENST00000358077.5
DAPK1
death-associated protein kinase 1
chr3_+_142315294 0.35 ENST00000464320.1
PLS1
plastin 1
chr14_-_55658252 0.35 ENST00000395425.2
DLGAP5
discs, large (Drosophila) homolog-associated protein 5
chr10_+_95256356 0.34 ENST00000371485.3
CEP55
centrosomal protein 55kDa
chr10_-_5060201 0.34 ENST00000407674.1
AKR1C2
aldo-keto reductase family 1, member C2
chr12_+_65672702 0.33 ENST00000538045.1
ENST00000535239.1
MSRB3
methionine sulfoxide reductase B3
chr3_+_142315225 0.32 ENST00000457734.2
ENST00000483373.1
ENST00000475296.1
ENST00000495744.1
ENST00000476044.1
ENST00000461644.1
PLS1
plastin 1
chr10_-_5060147 0.32 ENST00000604507.1
AKR1C2
aldo-keto reductase family 1, member C2
chr11_-_115127611 0.31 ENST00000545094.1
CADM1
cell adhesion molecule 1
chr2_+_53994927 0.31 ENST00000295304.4
CHAC2
ChaC, cation transport regulator homolog 2 (E. coli)
chrX_-_10645724 0.30 ENST00000413894.1
MID1
midline 1 (Opitz/BBB syndrome)
chr2_+_102758271 0.30 ENST00000428279.1
IL1R1
interleukin 1 receptor, type I
chr22_+_35776828 0.30 ENST00000216117.8
HMOX1
heme oxygenase (decycling) 1
chr17_+_80816395 0.30 ENST00000576160.2
ENST00000571712.1
TBCD
tubulin folding cofactor D
chr3_+_160117087 0.29 ENST00000357388.3
SMC4
structural maintenance of chromosomes 4
chr3_-_194207388 0.29 ENST00000457986.1
ATP13A3
ATPase type 13A3
chr1_-_200589859 0.29 ENST00000367350.4
KIF14
kinesin family member 14
chr20_+_25388293 0.29 ENST00000262460.4
ENST00000429262.2
GINS1
GINS complex subunit 1 (Psf1 homolog)
chr15_-_90294523 0.28 ENST00000300057.4
MESP1
mesoderm posterior 1 homolog (mouse)
chrX_-_46187069 0.28 ENST00000446884.1
RP1-30G7.2
RP1-30G7.2
chr13_+_34392185 0.28 ENST00000380071.3
RFC3
replication factor C (activator 1) 3, 38kDa
chr8_+_27631903 0.28 ENST00000305188.8
ESCO2
establishment of sister chromatid cohesion N-acetyltransferase 2
chr15_-_80695917 0.28 ENST00000559008.1
RP11-210M15.2
Uncharacterized protein
chr11_-_615570 0.28 ENST00000525445.1
ENST00000348655.6
ENST00000397566.1
IRF7
interferon regulatory factor 7
chr6_-_110500826 0.27 ENST00000265601.3
ENST00000447287.1
ENST00000444391.1
WASF1
WAS protein family, member 1
chr2_-_191878874 0.27 ENST00000392322.3
ENST00000392323.2
ENST00000424722.1
ENST00000361099.3
STAT1
signal transducer and activator of transcription 1, 91kDa
chr19_+_859654 0.27 ENST00000592860.1
CFD
complement factor D (adipsin)
chr17_+_79849872 0.27 ENST00000584197.1
ENST00000583839.1
ANAPC11
anaphase promoting complex subunit 11
chr12_+_93965609 0.27 ENST00000549887.1
ENST00000551556.1
SOCS2
suppressor of cytokine signaling 2
chr12_+_57854274 0.27 ENST00000528432.1
GLI1
GLI family zinc finger 1
chr17_+_7590734 0.27 ENST00000457584.2
WRAP53
WD repeat containing, antisense to TP53
chr11_-_414948 0.26 ENST00000530494.1
ENST00000528209.1
ENST00000431843.2
ENST00000528058.1
SIGIRR
single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
chr16_+_31271274 0.26 ENST00000287497.8
ENST00000544665.3
ITGAM
integrin, alpha M (complement component 3 receptor 3 subunit)
chr17_+_25799008 0.26 ENST00000583370.1
ENST00000398988.3
ENST00000268763.6
KSR1
kinase suppressor of ras 1
chr10_-_72142345 0.25 ENST00000373224.1
ENST00000446961.1
ENST00000358141.2
ENST00000357631.2
LRRC20
leucine rich repeat containing 20
chr1_+_213123976 0.25 ENST00000366965.2
ENST00000366967.2
VASH2
vasohibin 2
chr20_-_656437 0.25 ENST00000488788.2
RP5-850E9.3
Uncharacterized protein
chr17_-_36884451 0.25 ENST00000595377.1
AC006449.1
NS5ATP13TP1; Uncharacterized protein
chr11_-_92931098 0.25 ENST00000326402.4
SLC36A4
solute carrier family 36 (proton/amino acid symporter), member 4
chr17_+_76210367 0.25 ENST00000592734.1
ENST00000587746.1
BIRC5
baculoviral IAP repeat containing 5
chr2_+_201994042 0.24 ENST00000417748.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr16_+_66461175 0.24 ENST00000536005.2
ENST00000299694.8
ENST00000561796.1
BEAN1
brain expressed, associated with NEDD4, 1
chr8_+_103876528 0.24 ENST00000522939.1
ENST00000524007.1
KB-1507C5.2
HCG15011, isoform CRA_a; Protein LOC100996457
chr1_-_21625486 0.24 ENST00000481130.2
ECE1
endothelin converting enzyme 1
chr17_+_79849782 0.24 ENST00000392376.3
ANAPC11
anaphase promoting complex subunit 11
chr7_-_100239132 0.24 ENST00000223051.3
ENST00000431692.1
TFR2
transferrin receptor 2
chr10_+_81967456 0.23 ENST00000422847.1
LINC00857
long intergenic non-protein coding RNA 857
chr17_+_79849523 0.23 ENST00000572639.1
ENST00000579978.1
ENST00000344877.5
ENST00000582222.1
ENST00000577425.1
ENST00000571024.2
ENST00000574924.2
ENST00000572851.2
ENST00000357385.3
ENST00000584314.1
ENST00000571874.2
ENST00000578550.1
ENST00000577747.1
ENST00000579133.1
ANAPC11
anaphase promoting complex subunit 11
chr7_+_114562172 0.23 ENST00000393486.1
ENST00000257724.3
MDFIC
MyoD family inhibitor domain containing
chr11_+_66790816 0.23 ENST00000527043.1
SYT12
synaptotagmin XII
chr2_+_87808725 0.23 ENST00000413202.1
LINC00152
long intergenic non-protein coding RNA 152
chr7_-_35077653 0.23 ENST00000310974.4
DPY19L1
dpy-19-like 1 (C. elegans)
chr19_+_47634039 0.23 ENST00000597808.1
ENST00000413379.3
ENST00000600706.1
ENST00000540850.1
ENST00000598840.1
ENST00000600753.1
ENST00000270225.7
ENST00000392776.3
SAE1
SUMO1 activating enzyme subunit 1
chr17_-_79849438 0.22 ENST00000331204.4
ENST00000505490.2
ALYREF
Aly/REF export factor
chr2_+_102758210 0.22 ENST00000450319.1
IL1R1
interleukin 1 receptor, type I
chr2_-_27498186 0.22 ENST00000447008.2
SLC30A3
solute carrier family 30 (zinc transporter), member 3
chr15_-_52483566 0.22 ENST00000261837.7
GNB5
guanine nucleotide binding protein (G protein), beta 5
chr2_+_189156586 0.22 ENST00000409830.1
GULP1
GULP, engulfment adaptor PTB domain containing 1
chr9_-_103115135 0.21 ENST00000537512.1
TEX10
testis expressed 10
chr7_-_108209897 0.21 ENST00000313516.5
THAP5
THAP domain containing 5
chr9_+_26956474 0.21 ENST00000429045.2
IFT74
intraflagellar transport 74 homolog (Chlamydomonas)
chr20_-_271009 0.21 ENST00000382369.5
C20orf96
chromosome 20 open reading frame 96
chr1_-_47779762 0.21 ENST00000371877.3
ENST00000360380.3
ENST00000337817.5
ENST00000447475.2
STIL
SCL/TAL1 interrupting locus
chr11_-_74204742 0.21 ENST00000310109.4
LIPT2
lipoyl(octanoyl) transferase 2 (putative)
chr2_+_201994208 0.21 ENST00000440180.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr22_-_41215328 0.20 ENST00000434185.1
ENST00000435456.2
SLC25A17
solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17
chrX_-_133930285 0.20 ENST00000486347.1
ENST00000343004.5
FAM122B
family with sequence similarity 122B
chr15_-_55581954 0.20 ENST00000336787.1
RAB27A
RAB27A, member RAS oncogene family
chr21_-_46962379 0.20 ENST00000311124.4
ENST00000380010.4
SLC19A1
solute carrier family 19 (folate transporter), member 1
chr17_+_46185111 0.20 ENST00000582104.1
ENST00000584335.1
SNX11
sorting nexin 11
chr2_+_102758751 0.20 ENST00000442590.1
IL1R1
interleukin 1 receptor, type I
chr10_-_99531709 0.19 ENST00000266066.3
SFRP5
secreted frizzled-related protein 5
chr11_+_61447845 0.19 ENST00000257215.5
DAGLA
diacylglycerol lipase, alpha
chr2_-_148778323 0.19 ENST00000440042.1
ENST00000535373.1
ENST00000540442.1
ENST00000536575.1
ORC4
origin recognition complex, subunit 4
chr14_-_35591156 0.19 ENST00000554361.1
PPP2R3C
protein phosphatase 2, regulatory subunit B'', gamma
chr1_+_35734616 0.19 ENST00000441447.1
ZMYM4
zinc finger, MYM-type 4
chr7_+_107220660 0.19 ENST00000465919.1
ENST00000445771.2
ENST00000479917.1
ENST00000421217.1
ENST00000457837.1
BCAP29
B-cell receptor-associated protein 29
chr17_-_47925379 0.19 ENST00000352793.2
ENST00000334568.4
ENST00000398154.1
ENST00000436235.1
ENST00000326219.5
TAC4
tachykinin 4 (hemokinin)
chr12_+_52430894 0.19 ENST00000546842.1
NR4A1
nuclear receptor subfamily 4, group A, member 1
chr6_-_97731019 0.19 ENST00000275053.4
MMS22L
MMS22-like, DNA repair protein
chr9_-_35815013 0.18 ENST00000259667.5
HINT2
histidine triad nucleotide binding protein 2
chr1_+_15736359 0.18 ENST00000375980.4
EFHD2
EF-hand domain family, member D2
chr19_-_40772221 0.18 ENST00000441941.2
ENST00000580747.1
AKT2
v-akt murine thymoma viral oncogene homolog 2
chr2_-_242242133 0.18 ENST00000430918.1
HDLBP
high density lipoprotein binding protein
chr19_+_859425 0.18 ENST00000327726.6
CFD
complement factor D (adipsin)
chr5_+_150040403 0.18 ENST00000517768.1
ENST00000297130.4
MYOZ3
myozenin 3
chr11_-_236326 0.18 ENST00000525237.1
ENST00000532956.1
ENST00000525319.1
ENST00000524564.1
ENST00000382743.4
SIRT3
sirtuin 3
chrX_-_19689106 0.18 ENST00000379716.1
SH3KBP1
SH3-domain kinase binding protein 1
chr9_+_127023704 0.18 ENST00000373596.1
ENST00000425237.1
NEK6
NIMA-related kinase 6
chr17_-_7590745 0.18 ENST00000514944.1
ENST00000503591.1
ENST00000455263.2
ENST00000420246.2
ENST00000445888.2
ENST00000509690.1
ENST00000604348.1
ENST00000269305.4
TP53
tumor protein p53
chr1_+_222988363 0.18 ENST00000450784.1
ENST00000426045.1
ENST00000457955.1
ENST00000444858.1
ENST00000435378.1
ENST00000441676.1
RP11-452F19.3
RP11-452F19.3
chr11_-_6440624 0.18 ENST00000311051.3
APBB1
amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
chr11_+_65029233 0.18 ENST00000265465.3
POLA2
polymerase (DNA directed), alpha 2, accessory subunit
chr16_-_30440530 0.18 ENST00000568434.1
DCTPP1
dCTP pyrophosphatase 1
chr6_-_125623046 0.18 ENST00000608295.1
ENST00000398153.2
ENST00000608284.1
ENST00000368377.4
HDDC2
HD domain containing 2
chr1_-_205290865 0.17 ENST00000367157.3
NUAK2
NUAK family, SNF1-like kinase, 2
chr18_+_43684310 0.17 ENST00000592471.1
ENST00000585518.1
HAUS1
HAUS augmin-like complex, subunit 1
chr4_+_2626988 0.17 ENST00000509050.1
FAM193A
family with sequence similarity 193, member A
chr1_-_52456352 0.17 ENST00000371655.3
RAB3B
RAB3B, member RAS oncogene family
chrX_-_119709637 0.17 ENST00000404115.3
CUL4B
cullin 4B
chr12_+_56660633 0.17 ENST00000308197.5
COQ10A
coenzyme Q10 homolog A (S. cerevisiae)
chr10_+_94833642 0.17 ENST00000224356.4
ENST00000394139.1
CYP26A1
cytochrome P450, family 26, subfamily A, polypeptide 1
chr3_+_121554046 0.17 ENST00000273668.2
ENST00000451944.2
EAF2
ELL associated factor 2
chr6_-_30684898 0.17 ENST00000422266.1
ENST00000416571.1
MDC1
mediator of DNA-damage checkpoint 1
chr9_+_26956371 0.17 ENST00000380062.5
ENST00000518614.1
IFT74
intraflagellar transport 74 homolog (Chlamydomonas)
chr11_+_74204883 0.17 ENST00000528481.1
POLD3
polymerase (DNA-directed), delta 3, accessory subunit
chr5_-_78281775 0.17 ENST00000396151.3
ENST00000565165.1
ARSB
arylsulfatase B
chr1_-_245026388 0.17 ENST00000440865.1
HNRNPU
heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
chr17_+_16945820 0.16 ENST00000577514.1
MPRIP
myosin phosphatase Rho interacting protein
chr5_-_55290773 0.16 ENST00000502326.3
ENST00000381298.2
IL6ST
interleukin 6 signal transducer (gp130, oncostatin M receptor)
chr9_-_117150303 0.16 ENST00000312033.3
AKNA
AT-hook transcription factor
chr22_-_42915788 0.16 ENST00000323013.6
RRP7A
ribosomal RNA processing 7 homolog A (S. cerevisiae)
chr17_+_44803922 0.16 ENST00000465370.1
NSF
N-ethylmaleimide-sensitive factor
chr19_-_43702231 0.16 ENST00000597374.1
ENST00000599371.1
PSG4
pregnancy specific beta-1-glycoprotein 4
chr14_-_35183755 0.16 ENST00000555765.1
CFL2
cofilin 2 (muscle)
chr14_-_51562037 0.16 ENST00000338969.5
TRIM9
tripartite motif containing 9
chr16_-_67450325 0.16 ENST00000348579.2
ZDHHC1
zinc finger, DHHC-type containing 1
chr19_-_45748628 0.16 ENST00000590022.1
AC006126.4
AC006126.4
chr19_-_55668093 0.16 ENST00000588882.1
ENST00000586858.1
TNNI3
troponin I type 3 (cardiac)
chr3_+_101498269 0.16 ENST00000491511.2
NXPE3
neurexophilin and PC-esterase domain family, member 3
chr3_+_119217422 0.15 ENST00000466984.1
TIMMDC1
translocase of inner mitochondrial membrane domain containing 1
chr7_+_99036996 0.15 ENST00000441580.1
ENST00000412686.1
CPSF4
cleavage and polyadenylation specific factor 4, 30kDa
chr4_-_83931862 0.15 ENST00000506560.1
ENST00000442461.2
ENST00000446851.2
ENST00000340417.3
LIN54
lin-54 homolog (C. elegans)
chr8_+_21823726 0.15 ENST00000433566.4
XPO7
exportin 7
chr12_-_49318715 0.15 ENST00000444214.2
FKBP11
FK506 binding protein 11, 19 kDa
chr22_-_42342733 0.15 ENST00000402420.1
CENPM
centromere protein M
chr19_-_40786733 0.15 ENST00000486368.2
AKT2
v-akt murine thymoma viral oncogene homolog 2
chrX_-_10645773 0.15 ENST00000453318.2
MID1
midline 1 (Opitz/BBB syndrome)
chr20_+_36012051 0.15 ENST00000373567.2
SRC
v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
chr22_+_22988816 0.15 ENST00000480559.1
ENST00000448514.1
GGTLC2
gamma-glutamyltransferase light chain 2
chr19_+_36236514 0.15 ENST00000222266.2
PSENEN
presenilin enhancer gamma secretase subunit
chr11_-_114271139 0.15 ENST00000325636.4
C11orf71
chromosome 11 open reading frame 71
chr1_+_9599540 0.14 ENST00000302692.6
SLC25A33
solute carrier family 25 (pyrimidine nucleotide carrier), member 33
chr7_-_127032741 0.14 ENST00000393313.1
ENST00000265827.3
ENST00000434602.1
ZNF800
zinc finger protein 800
chr5_+_102090974 0.14 ENST00000512073.1
PAM
peptidylglycine alpha-amidating monooxygenase
chr9_-_34329198 0.14 ENST00000379166.2
ENST00000345050.2
KIF24
kinesin family member 24
chr2_+_33701286 0.14 ENST00000403687.3
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr11_+_12115543 0.14 ENST00000537344.1
ENST00000532179.1
ENST00000526065.1
MICAL2
microtubule associated monooxygenase, calponin and LIM domain containing 2
chr3_+_184016986 0.14 ENST00000417952.1
PSMD2
proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
chr22_+_24823517 0.14 ENST00000496258.1
ENST00000337539.7
ADORA2A
adenosine A2a receptor
chr2_-_136743436 0.14 ENST00000441323.1
ENST00000449218.1
DARS
aspartyl-tRNA synthetase
chr17_+_46184911 0.14 ENST00000580219.1
ENST00000452859.2
ENST00000393405.2
ENST00000439357.2
ENST00000359238.2
SNX11
sorting nexin 11
chr11_-_112034831 0.14 ENST00000280357.7
IL18
interleukin 18 (interferon-gamma-inducing factor)
chr2_+_136343904 0.14 ENST00000436436.1
R3HDM1
R3H domain containing 1
chr8_-_17533838 0.14 ENST00000400046.1
MTUS1
microtubule associated tumor suppressor 1
chr11_-_615942 0.14 ENST00000397562.3
ENST00000330243.5
ENST00000397570.1
ENST00000397574.2
IRF7
interferon regulatory factor 7
chr17_-_1553346 0.14 ENST00000301336.6
RILP
Rab interacting lysosomal protein
chr12_-_111180644 0.13 ENST00000551676.1
ENST00000550991.1
ENST00000335007.5
ENST00000340766.5
PPP1CC
protein phosphatase 1, catalytic subunit, gamma isozyme
chr8_-_145911188 0.13 ENST00000540274.1
ARHGAP39
Rho GTPase activating protein 39
chr10_+_127408263 0.13 ENST00000337623.3
C10orf137
erythroid differentiation regulatory factor 1
chr3_+_25469724 0.13 ENST00000437042.2
RARB
retinoic acid receptor, beta
chr12_+_52431016 0.13 ENST00000553200.1
NR4A1
nuclear receptor subfamily 4, group A, member 1
chr12_-_107380910 0.13 ENST00000392830.2
ENST00000240050.4
MTERFD3
MTERF domain containing 3
chr1_+_156105878 0.13 ENST00000508500.1
LMNA
lamin A/C
chr17_-_7232585 0.13 ENST00000571887.1
ENST00000315614.7
ENST00000399464.2
ENST00000570460.1
NEURL4
neuralized E3 ubiquitin protein ligase 4
chr11_-_71751715 0.13 ENST00000535947.1
NUMA1
nuclear mitotic apparatus protein 1
chr7_+_107220899 0.13 ENST00000379117.2
ENST00000473124.1
BCAP29
B-cell receptor-associated protein 29
chr2_+_26467762 0.13 ENST00000317799.5
ENST00000405867.3
ENST00000537713.1
HADHB
hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit
chr4_-_170924888 0.13 ENST00000502832.1
ENST00000393704.3
MFAP3L
microfibrillar-associated protein 3-like
chr14_+_32546274 0.13 ENST00000396582.2
ARHGAP5
Rho GTPase activating protein 5
chr14_+_32546145 0.13 ENST00000556611.1
ENST00000539826.2
ARHGAP5
Rho GTPase activating protein 5
chr14_-_21994337 0.13 ENST00000537235.1
ENST00000450879.2
SALL2
spalt-like transcription factor 2
chrX_+_70503037 0.12 ENST00000535149.1
NONO
non-POU domain containing, octamer-binding
chr3_+_148447887 0.12 ENST00000475347.1
ENST00000474935.1
ENST00000461609.1
AGTR1
angiotensin II receptor, type 1
chr19_-_41942344 0.12 ENST00000594660.1
ATP5SL
ATP5S-like
chr12_-_12849073 0.12 ENST00000332427.2
ENST00000540796.1
GPR19
G protein-coupled receptor 19
chr4_+_105828537 0.12 ENST00000515649.1
RP11-556I14.1
RP11-556I14.1
chr6_-_26027480 0.12 ENST00000377364.3
HIST1H4B
histone cluster 1, H4b
chr2_-_103353277 0.12 ENST00000258436.5
MFSD9
major facilitator superfamily domain containing 9
chr3_+_32726774 0.12 ENST00000538368.1
CNOT10
CCR4-NOT transcription complex, subunit 10

Network of associatons between targets according to the STRING database.

First level regulatory network of TBX2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0100012 regulation of heart induction(GO:0090381) regulation of heart induction by canonical Wnt signaling pathway(GO:0100012)
0.2 0.8 GO:0060032 notochord regression(GO:0060032)
0.1 0.8 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.1 0.7 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.1 1.2 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.1 0.3 GO:0043132 coenzyme A transport(GO:0015880) coenzyme A transmembrane transport(GO:0035349) NAD transport(GO:0043132) adenosine 3',5'-bisphosphate transmembrane transport(GO:0071106) AMP transport(GO:0080121)
0.1 0.7 GO:1902896 terminal web assembly(GO:1902896)
0.1 0.3 GO:0032203 telomere formation via telomerase(GO:0032203)
0.1 0.4 GO:2000110 negative regulation of macrophage apoptotic process(GO:2000110)
0.1 0.7 GO:0009753 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.1 0.3 GO:0006788 heme oxidation(GO:0006788) negative regulation of mast cell cytokine production(GO:0032764)
0.1 0.3 GO:0046725 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308)
0.1 0.8 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.1 0.5 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.1 0.3 GO:0009107 lipoate biosynthetic process(GO:0009107)
0.1 0.8 GO:0030091 protein repair(GO:0030091)
0.1 0.2 GO:0050760 negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.1 0.2 GO:0061580 colon epithelial cell migration(GO:0061580)
0.1 0.7 GO:1901970 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.1 0.3 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.8 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.2 GO:0098838 reduced folate transmembrane transport(GO:0098838)
0.0 0.1 GO:1990519 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.0 0.2 GO:0098917 retrograde trans-synaptic signaling(GO:0098917)
0.0 0.3 GO:0071486 cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.0 0.3 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.0 0.3 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.1 GO:0070676 intralumenal vesicle formation(GO:0070676)
0.0 0.2 GO:0051097 negative regulation of helicase activity(GO:0051097) oligodendrocyte apoptotic process(GO:0097252)
0.0 1.3 GO:0032060 bleb assembly(GO:0032060)
0.0 0.1 GO:0009644 response to high light intensity(GO:0009644)
0.0 0.3 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0 0.2 GO:0010814 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.0 0.2 GO:0097460 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.0 0.2 GO:0035544 negative regulation of SNARE complex assembly(GO:0035544)
0.0 0.1 GO:0006097 glyoxylate cycle(GO:0006097)
0.0 0.5 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 0.3 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.0 0.1 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
0.0 0.2 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 0.1 GO:0019417 sulfur oxidation(GO:0019417)
0.0 0.2 GO:0009149 pyrimidine nucleoside triphosphate catabolic process(GO:0009149) pyrimidine deoxyribonucleoside triphosphate catabolic process(GO:0009213)
0.0 0.2 GO:0051582 peptidyl-cysteine methylation(GO:0018125) positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
0.0 0.2 GO:0034653 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.0 0.9 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.0 0.1 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.0 0.2 GO:0046778 modification by virus of host mRNA processing(GO:0046778)
0.0 0.2 GO:0033504 floor plate development(GO:0033504)
0.0 0.1 GO:0048319 mesoderm migration involved in gastrulation(GO:0007509) axial mesoderm morphogenesis(GO:0048319)
0.0 0.1 GO:0060931 sinoatrial node cell development(GO:0060931)
0.0 0.3 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.2 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.0 0.1 GO:0043457 regulation of cellular respiration(GO:0043457)
0.0 0.6 GO:0006751 glutathione catabolic process(GO:0006751)
0.0 0.2 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.0 0.6 GO:0070914 UV-damage excision repair(GO:0070914)
0.0 0.3 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.1 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.2 GO:0046878 positive regulation of saliva secretion(GO:0046878)
0.0 0.1 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.0 0.4 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.1 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.0 0.4 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.4 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.0 0.3 GO:0035965 cardiolipin acyl-chain remodeling(GO:0035965)
0.0 0.5 GO:0072520 seminiferous tubule development(GO:0072520)
0.0 0.1 GO:1904845 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.0 0.1 GO:0018032 protein amidation(GO:0018032)
0.0 0.1 GO:2001162 regulation of histone H3-K79 methylation(GO:2001160) positive regulation of histone H3-K79 methylation(GO:2001162)
0.0 0.1 GO:0042231 interleukin-13 biosynthetic process(GO:0042231)
0.0 0.4 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.2 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.0 0.1 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.1 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.0 0.2 GO:0015827 tryptophan transport(GO:0015827) proline transmembrane transport(GO:0035524)
0.0 0.1 GO:0055073 cadmium ion homeostasis(GO:0055073)
0.0 0.3 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.2 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
0.0 0.2 GO:0018103 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0 0.1 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.0 0.1 GO:0014057 positive regulation of acetylcholine secretion, neurotransmission(GO:0014057)
0.0 0.5 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.1 GO:0035803 egg coat formation(GO:0035803)
0.0 0.2 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.2 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 0.1 GO:0000412 histone peptidyl-prolyl isomerization(GO:0000412)
0.0 0.2 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.0 0.2 GO:0002759 regulation of antimicrobial humoral response(GO:0002759)
0.0 0.1 GO:0035720 intraciliary anterograde transport(GO:0035720) ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.0 0.1 GO:0070901 mitochondrial tRNA methylation(GO:0070901)
0.0 0.1 GO:0010645 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
0.0 0.1 GO:0043449 cellular alkene metabolic process(GO:0043449)
0.0 0.1 GO:0006429 glutaminyl-tRNA aminoacylation(GO:0006425) leucyl-tRNA aminoacylation(GO:0006429)
0.0 0.2 GO:0035494 SNARE complex disassembly(GO:0035494)
0.0 0.2 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.2 GO:1901386 negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.0 0.3 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.0 0.9 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.4 GO:0033630 positive regulation of cell adhesion mediated by integrin(GO:0033630)
0.0 0.1 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.0 0.2 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0 0.2 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.1 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.1 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.0 0.1 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.1 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.1 GO:1902846 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.0 0.5 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.1 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0 0.1 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.0 0.4 GO:0031297 replication fork processing(GO:0031297)
0.0 0.1 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.1 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.0 0.3 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.3 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.1 GO:0050955 thermoception(GO:0050955)
0.0 0.2 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.0 0.1 GO:0090131 mesenchyme migration(GO:0090131)
0.0 0.3 GO:0032201 telomere maintenance via semi-conservative replication(GO:0032201)
0.0 0.1 GO:0034628 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.0 0.2 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.0 GO:0061101 neuroendocrine cell differentiation(GO:0061101)
0.0 0.1 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.0 0.2 GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.0 0.0 GO:0032827 negative regulation of natural killer cell differentiation(GO:0032824) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827) positive regulation of cytolysis in other organism(GO:0051714)
0.0 0.1 GO:0006824 cobalt ion transport(GO:0006824)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0032133 chromosome passenger complex(GO:0032133)
0.1 0.3 GO:0000811 GINS complex(GO:0000811)
0.1 0.8 GO:0000796 condensin complex(GO:0000796)
0.1 0.2 GO:0035101 FACT complex(GO:0035101)
0.1 0.6 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1 0.2 GO:0032783 ELL-EAF complex(GO:0032783)
0.1 0.4 GO:0031262 Ndc80 complex(GO:0031262)
0.1 0.2 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.0 0.1 GO:0034515 proteasome storage granule(GO:0034515)
0.0 0.2 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.0 0.7 GO:0032039 integrator complex(GO:0032039)
0.0 0.2 GO:0031302 intrinsic component of endosome membrane(GO:0031302)
0.0 0.3 GO:1990357 terminal web(GO:1990357)
0.0 0.6 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.0 0.9 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.3 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.0 1.3 GO:0043218 compact myelin(GO:0043218)
0.0 0.3 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.5 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.2 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.2 GO:1990584 cardiac Troponin complex(GO:1990584)
0.0 0.2 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.2 GO:0043196 varicosity(GO:0043196)
0.0 0.1 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 0.5 GO:0031265 CD95 death-inducing signaling complex(GO:0031265) ripoptosome(GO:0097342)
0.0 0.3 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.7 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.2 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 1.2 GO:0097542 ciliary tip(GO:0097542)
0.0 0.2 GO:1990812 growth cone filopodium(GO:1990812)
0.0 0.3 GO:0090543 Flemming body(GO:0090543)
0.0 0.2 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.2 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.1 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.1 GO:0042643 actomyosin, actin portion(GO:0042643)
0.0 0.2 GO:0034464 BBSome(GO:0034464)
0.0 0.1 GO:0005638 lamin filament(GO:0005638)
0.0 0.2 GO:0031209 SCAR complex(GO:0031209)
0.0 0.1 GO:0044294 dendritic growth cone(GO:0044294)
0.0 1.0 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.2 GO:0070652 HAUS complex(GO:0070652)
0.0 0.0 GO:0070195 growth hormone receptor complex(GO:0070195)
0.0 0.4 GO:0051233 spindle midzone(GO:0051233)
0.0 0.2 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.1 GO:0042382 paraspeckles(GO:0042382)
0.0 0.1 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.0 0.2 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.0 GO:0008043 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.1 0.8 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.1 0.9 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.1 0.3 GO:0080122 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.1 0.7 GO:0047086 phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086)
0.1 0.3 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.1 0.2 GO:0019948 SUMO activating enzyme activity(GO:0019948)
0.1 0.3 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.1 0.2 GO:0015633 zinc transporting ATPase activity(GO:0015633)
0.1 0.5 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
0.1 0.2 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.1 0.2 GO:0004998 transferrin receptor activity(GO:0004998)
0.0 0.2 GO:0008518 reduced folate carrier activity(GO:0008518)
0.0 0.1 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.0 0.3 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0 0.1 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.0 0.2 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.0 0.2 GO:0004915 interleukin-6 receptor activity(GO:0004915) leukemia inhibitory factor receptor activity(GO:0004923) interleukin-6 binding(GO:0019981)
0.0 0.1 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.0 0.3 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.0 0.3 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.2 GO:0051373 FATZ binding(GO:0051373)
0.0 0.7 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.3 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.2 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.1 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.0 0.1 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.0 0.2 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
0.0 0.1 GO:0097003 adipokinetic hormone receptor activity(GO:0097003)
0.0 0.4 GO:0048019 receptor antagonist activity(GO:0048019)
0.0 0.1 GO:0051139 metal ion:proton antiporter activity(GO:0051139)
0.0 0.3 GO:0001851 complement component C3b binding(GO:0001851)
0.0 0.1 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.3 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.0 0.7 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.3 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.2 GO:0071253 connexin binding(GO:0071253)
0.0 0.1 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.1 GO:0004823 glutamine-tRNA ligase activity(GO:0004819) leucine-tRNA ligase activity(GO:0004823)
0.0 0.2 GO:0032552 deoxyribonucleotide binding(GO:0032552)
0.0 0.2 GO:0048039 ubiquinone binding(GO:0048039)
0.0 0.1 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.1 GO:0016403 dimethylargininase activity(GO:0016403)
0.0 0.3 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 0.3 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.1 GO:0031812 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.0 0.0 GO:0035034 histone acetyltransferase regulator activity(GO:0035034)
0.0 0.1 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.3 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.1 GO:0042610 CD8 receptor binding(GO:0042610)
0.0 0.2 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0 0.1 GO:0047685 amine sulfotransferase activity(GO:0047685)
0.0 0.1 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.0 0.7 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.1 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.0 0.3 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.0 GO:0005148 prolactin receptor binding(GO:0005148)
0.0 0.2 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.0 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.0 0.5 GO:0005123 death receptor binding(GO:0005123)
0.0 1.0 GO:0019843 rRNA binding(GO:0019843)
0.0 0.5 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.4 GO:0031489 myosin V binding(GO:0031489)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.1 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 1.8 PID AURORA B PATHWAY Aurora B signaling
0.0 1.1 PID AURORA A PATHWAY Aurora A signaling
0.0 0.5 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.8 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.4 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 1.3 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.4 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.8 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.0 0.7 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.0 0.4 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 1.0 REACTOME KINESINS Genes involved in Kinesins
0.0 0.4 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.7 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.0 0.3 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.5 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 0.2 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 0.3 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.2 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.2 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 1.0 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.3 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.4 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.3 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.8 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling