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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for TBX20

Z-value: 0.38

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Transcription factors associated with TBX20

Gene Symbol Gene ID Gene Info
TBX20
ENSG00000164532.10 T-box transcription factor 20

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TBX20hg19_v2_chr7_-_35293740_352937580.135.8e-01Click!

Activity profile of TBX20 motif

Sorted Z-values of TBX20 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr16_+_57662527 4.41 ENST00000563374.1
ENST00000568234.1
ENST00000565770.1
ENST00000564338.1
ENST00000566164.1
GPR56
G protein-coupled receptor 56
chr16_+_57662596 2.17 ENST00000567397.1
ENST00000568979.1
GPR56
G protein-coupled receptor 56
chr16_+_57662419 1.71 ENST00000388812.4
ENST00000538815.1
ENST00000456916.1
ENST00000567154.1
ENST00000388813.5
ENST00000562558.1
ENST00000566271.2
GPR56
G protein-coupled receptor 56
chr3_+_40428647 0.67 ENST00000301825.3
ENST00000439533.1
ENST00000456402.1
ENTPD3
ectonucleoside triphosphate diphosphohydrolase 3
chr2_+_64068116 0.51 ENST00000480679.1
UGP2
UDP-glucose pyrophosphorylase 2
chr11_-_14358620 0.41 ENST00000531421.1
RRAS2
related RAS viral (r-ras) oncogene homolog 2
chr19_+_56915668 0.32 ENST00000333201.9
ENST00000391778.3
ZNF583
zinc finger protein 583
chr8_+_27182862 0.31 ENST00000521164.1
ENST00000346049.5
PTK2B
protein tyrosine kinase 2 beta
chr8_+_27183033 0.26 ENST00000420218.2
PTK2B
protein tyrosine kinase 2 beta
chr2_-_219134343 0.23 ENST00000447885.1
ENST00000420660.1
AAMP
angio-associated, migratory cell protein
chr2_+_64068074 0.22 ENST00000394417.2
ENST00000484142.1
ENST00000482668.1
ENST00000467648.2
UGP2
UDP-glucose pyrophosphorylase 2
chr3_-_15140629 0.22 ENST00000507357.1
ENST00000449050.1
ENST00000253699.3
ENST00000435849.3
ENST00000476527.2
ZFYVE20
zinc finger, FYVE domain containing 20
chr5_+_133861339 0.19 ENST00000282605.4
ENST00000361895.2
ENST00000402835.1
PHF15
jade family PHD finger 2
chr4_+_160025300 0.19 ENST00000505478.1
RAPGEF2
Rap guanine nucleotide exchange factor (GEF) 2
chr5_-_89825328 0.18 ENST00000500869.2
ENST00000315948.6
ENST00000509384.1
LYSMD3
LysM, putative peptidoglycan-binding, domain containing 3
chr2_+_61108771 0.16 ENST00000394479.3
REL
v-rel avian reticuloendotheliosis viral oncogene homolog
chr3_-_50396978 0.15 ENST00000266025.3
TMEM115
transmembrane protein 115
chr12_-_56123444 0.15 ENST00000546457.1
ENST00000549117.1
CD63
CD63 molecule
chr6_-_136788001 0.15 ENST00000544465.1
MAP7
microtubule-associated protein 7
chr12_-_76377795 0.14 ENST00000552856.1
RP11-114H23.1
RP11-114H23.1
chr2_+_85360499 0.14 ENST00000282111.3
TCF7L1
transcription factor 7-like 1 (T-cell specific, HMG-box)
chr20_+_44509857 0.13 ENST00000372523.1
ENST00000372520.1
ZSWIM1
zinc finger, SWIM-type containing 1
chr3_+_142315294 0.13 ENST00000464320.1
PLS1
plastin 1
chr7_+_30185496 0.12 ENST00000455738.1
C7orf41
maturin, neural progenitor differentiation regulator homolog (Xenopus)
chr3_-_131221771 0.12 ENST00000510154.1
ENST00000507669.1
MRPL3
mitochondrial ribosomal protein L3
chr3_+_142315225 0.10 ENST00000457734.2
ENST00000483373.1
ENST00000475296.1
ENST00000495744.1
ENST00000476044.1
ENST00000461644.1
PLS1
plastin 1
chr1_+_147013182 0.09 ENST00000234739.3
BCL9
B-cell CLL/lymphoma 9
chr17_-_76824975 0.09 ENST00000586066.2
USP36
ubiquitin specific peptidase 36
chr2_-_219134822 0.09 ENST00000444053.1
ENST00000248450.4
AAMP
angio-associated, migratory cell protein
chr2_+_207630081 0.08 ENST00000236980.6
ENST00000418289.1
ENST00000402774.3
ENST00000403094.3
FASTKD2
FAST kinase domains 2
chr2_+_176972000 0.08 ENST00000249504.5
HOXD11
homeobox D11
chr7_+_30185406 0.08 ENST00000324489.5
C7orf41
maturin, neural progenitor differentiation regulator homolog (Xenopus)
chr2_+_173940442 0.06 ENST00000409176.2
ENST00000338983.3
ENST00000431503.2
MLTK
Mitogen-activated protein kinase kinase kinase MLT
chr19_-_9325542 0.05 ENST00000308682.2
OR7D4
olfactory receptor, family 7, subfamily D, member 4
chr1_-_11118896 0.04 ENST00000465788.1
SRM
spermidine synthase
chr19_+_44331555 0.04 ENST00000590950.1
ZNF283
zinc finger protein 283
chrX_-_55291163 0.03 ENST00000519203.1
ENST00000374951.1
PAGE3
P antigen family, member 3 (prostate associated)
chr1_-_17380630 0.03 ENST00000375499.3
SDHB
succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
chr1_-_11865982 0.02 ENST00000418034.1
MTHFR
methylenetetrahydrofolate reductase (NAD(P)H)
chr7_-_33140498 0.02 ENST00000448915.1
RP9
retinitis pigmentosa 9 (autosomal dominant)
chr19_-_37958318 0.02 ENST00000316950.6
ENST00000591710.1
ZNF569
zinc finger protein 569
chr19_-_4540486 0.02 ENST00000306390.6
LRG1
leucine-rich alpha-2-glycoprotein 1
chr11_+_15136462 0.01 ENST00000379556.3
ENST00000424273.1
INSC
inscuteable homolog (Drosophila)
chr19_+_17579556 0.01 ENST00000442725.1
SLC27A1
solute carrier family 27 (fatty acid transporter), member 1
chr15_+_74421961 0.01 ENST00000565159.1
ENST00000567206.1
ISLR2
immunoglobulin superfamily containing leucine-rich repeat 2
chr22_+_41956767 0.01 ENST00000306149.7
CSDC2
cold shock domain containing C2, RNA binding
chr22_+_38219389 0.00 ENST00000249041.2
GALR3
galanin receptor 3
chr19_+_35810164 0.00 ENST00000598537.1
CD22
CD22 molecule

Network of associatons between targets according to the STRING database.

First level regulatory network of TBX20

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.1 0.6 GO:2000537 regulation of cGMP-mediated signaling(GO:0010752) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.1 0.7 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134)
0.0 0.2 GO:1902896 terminal web assembly(GO:1902896)
0.0 0.2 GO:2000670 positive regulation of dendritic cell apoptotic process(GO:2000670)
0.0 0.1 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0 0.1 GO:0035826 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:1990357 terminal web(GO:1990357)
0.0 0.6 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.1 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.0 0.1 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0051748 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.1 0.6 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.7 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 0.2 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.0 0.0 GO:0004766 spermidine synthase activity(GO:0004766)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.6 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions