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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for TBX3

Z-value: 0.62

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Transcription factors associated with TBX3

Gene Symbol Gene ID Gene Info
TBX3
ENSG00000135111.10 T-box transcription factor 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TBX3hg19_v2_chr12_-_115121962_1151219870.038.9e-01Click!

Activity profile of TBX3 motif

Sorted Z-values of TBX3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_149192475 1.88 ENST00000465758.1
TM4SF4
transmembrane 4 L six family member 4
chr4_+_155484155 1.52 ENST00000509493.1
FGB
fibrinogen beta chain
chr4_+_155484103 1.47 ENST00000302068.4
FGB
fibrinogen beta chain
chr3_+_149191723 1.32 ENST00000305354.4
TM4SF4
transmembrane 4 L six family member 4
chr22_+_24999114 1.21 ENST00000412658.1
ENST00000445029.1
ENST00000419133.1
ENST00000400382.1
ENST00000438643.2
ENST00000452551.1
ENST00000400383.1
ENST00000412898.1
ENST00000400380.1
ENST00000455483.1
ENST00000430289.1
GGT1
gamma-glutamyltransferase 1
chr6_+_32821924 1.05 ENST00000374859.2
ENST00000453265.2
PSMB9
proteasome (prosome, macropain) subunit, beta type, 9
chr15_-_74504597 0.95 ENST00000416286.3
STRA6
stimulated by retinoic acid 6
chr9_+_5231413 0.94 ENST00000239316.4
INSL4
insulin-like 4 (placenta)
chr15_-_74504560 0.88 ENST00000449139.2
STRA6
stimulated by retinoic acid 6
chr11_+_65190245 0.83 ENST00000499732.1
ENST00000501122.2
ENST00000601801.1
NEAT1
nuclear paraspeckle assembly transcript 1 (non-protein coding)
chr19_-_47735918 0.81 ENST00000449228.1
ENST00000300880.7
ENST00000341983.4
BBC3
BCL2 binding component 3
chr14_+_96722152 0.80 ENST00000216629.6
BDKRB1
bradykinin receptor B1
chr17_+_48351785 0.79 ENST00000507382.1
TMEM92
transmembrane protein 92
chr7_+_22766766 0.79 ENST00000426291.1
ENST00000401651.1
ENST00000258743.5
ENST00000420258.2
ENST00000407492.1
ENST00000401630.3
ENST00000406575.1
IL6
interleukin 6 (interferon, beta 2)
chr17_+_27895609 0.69 ENST00000581411.2
ENST00000301057.7
TP53I13
tumor protein p53 inducible protein 13
chr1_+_45274154 0.68 ENST00000450269.1
ENST00000453418.1
ENST00000409335.2
BTBD19
BTB (POZ) domain containing 19
chr12_+_7169887 0.63 ENST00000542978.1
C1S
complement component 1, s subcomponent
chr19_+_9361606 0.61 ENST00000456448.1
OR7E24
olfactory receptor, family 7, subfamily E, member 24
chr1_-_151342180 0.60 ENST00000424475.1
SELENBP1
selenium binding protein 1
chr8_-_40200903 0.58 ENST00000522486.1
CTA-392C11.1
CTA-392C11.1
chr7_+_73106926 0.57 ENST00000453316.1
WBSCR22
Williams Beuren syndrome chromosome region 22
chr15_-_74501310 0.56 ENST00000423167.2
ENST00000432245.2
STRA6
stimulated by retinoic acid 6
chr4_+_15704573 0.55 ENST00000265016.4
BST1
bone marrow stromal cell antigen 1
chr14_-_24912047 0.52 ENST00000553930.1
SDR39U1
short chain dehydrogenase/reductase family 39U, member 1
chr19_-_55791058 0.52 ENST00000587959.1
ENST00000585927.1
ENST00000587922.1
ENST00000585698.1
HSPBP1
HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
chr20_-_4229721 0.50 ENST00000379453.4
ADRA1D
adrenoceptor alpha 1D
chrX_+_52926322 0.50 ENST00000430150.2
ENST00000452021.2
ENST00000412319.1
FAM156B
family with sequence similarity 156, member B
chr11_-_73689037 0.48 ENST00000544615.1
UCP2
uncoupling protein 2 (mitochondrial, proton carrier)
chr22_-_39928823 0.48 ENST00000334678.3
RPS19BP1
ribosomal protein S19 binding protein 1
chr19_+_41103063 0.47 ENST00000308370.7
LTBP4
latent transforming growth factor beta binding protein 4
chr20_-_32580924 0.47 ENST00000432859.1
RP5-1125A11.1
RP5-1125A11.1
chr19_-_33360647 0.47 ENST00000590341.1
ENST00000587772.1
ENST00000023064.4
SLC7A9
solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
chr15_+_79603404 0.46 ENST00000299705.5
TMED3
transmembrane emp24 protein transport domain containing 3
chr19_+_41257084 0.46 ENST00000601393.1
SNRPA
small nuclear ribonucleoprotein polypeptide A
chr8_+_23386305 0.45 ENST00000519973.1
SLC25A37
solute carrier family 25 (mitochondrial iron transporter), member 37
chr7_+_99971068 0.45 ENST00000198536.2
ENST00000453419.1
PILRA
paired immunoglobin-like type 2 receptor alpha
chr16_-_68057770 0.45 ENST00000332395.5
DDX28
DEAD (Asp-Glu-Ala-Asp) box polypeptide 28
chr14_-_24911971 0.44 ENST00000555365.1
ENST00000399395.3
SDR39U1
short chain dehydrogenase/reductase family 39U, member 1
chr1_+_212606219 0.43 ENST00000366988.3
NENF
neudesin neurotrophic factor
chr5_+_140593509 0.42 ENST00000341948.4
PCDHB13
protocadherin beta 13
chr12_-_56120865 0.40 ENST00000548898.1
ENST00000552067.1
CD63
CD63 molecule
chr19_-_55677920 0.40 ENST00000524407.2
ENST00000526003.1
ENST00000534170.1
DNAAF3
dynein, axonemal, assembly factor 3
chr7_+_106415457 0.40 ENST00000490162.2
ENST00000470135.1
RP5-884M6.1
RP5-884M6.1
chr19_+_50148087 0.40 ENST00000601038.1
ENST00000595242.1
SCAF1
SR-related CTD-associated factor 1
chr1_+_151020175 0.40 ENST00000368926.5
C1orf56
chromosome 1 open reading frame 56
chr3_+_124223586 0.39 ENST00000393496.1
KALRN
kalirin, RhoGEF kinase
chr14_+_74416989 0.38 ENST00000334571.2
ENST00000554920.1
COQ6
coenzyme Q6 monooxygenase
chr13_-_46679144 0.37 ENST00000181383.4
CPB2
carboxypeptidase B2 (plasma)
chr12_-_56121612 0.37 ENST00000546939.1
CD63
CD63 molecule
chr6_-_33385655 0.36 ENST00000440279.3
ENST00000607266.1
CUTA
cutA divalent cation tolerance homolog (E. coli)
chr11_-_27722021 0.35 ENST00000356660.4
ENST00000418212.1
ENST00000533246.1
BDNF
brain-derived neurotrophic factor
chr17_+_20483037 0.35 ENST00000399044.1
CDRT15L2
CMT1A duplicated region transcript 15-like 2
chr9_+_35490101 0.34 ENST00000361226.3
RUSC2
RUN and SH3 domain containing 2
chr22_-_21581926 0.34 ENST00000401924.1
GGT2
gamma-glutamyltransferase 2
chr8_-_121825088 0.33 ENST00000520717.1
SNTB1
syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
chr19_-_42724261 0.33 ENST00000595337.1
DEDD2
death effector domain containing 2
chr8_-_40200877 0.32 ENST00000521030.1
CTA-392C11.1
CTA-392C11.1
chr10_-_90611566 0.32 ENST00000371930.4
ANKRD22
ankyrin repeat domain 22
chr19_-_43835582 0.32 ENST00000595748.1
CTC-490G23.2
CTC-490G23.2
chr14_+_96505659 0.32 ENST00000555004.1
C14orf132
chromosome 14 open reading frame 132
chr12_-_56120838 0.32 ENST00000548160.1
CD63
CD63 molecule
chr1_-_242612726 0.32 ENST00000459864.1
PLD5
phospholipase D family, member 5
chr22_-_38480100 0.32 ENST00000427592.1
SLC16A8
solute carrier family 16 (monocarboxylate transporter), member 8
chr3_-_178984759 0.31 ENST00000349697.2
ENST00000497599.1
KCNMB3
potassium large conductance calcium-activated channel, subfamily M beta member 3
chr18_-_25616519 0.31 ENST00000399380.3
CDH2
cadherin 2, type 1, N-cadherin (neuronal)
chr1_-_242612779 0.31 ENST00000427495.1
PLD5
phospholipase D family, member 5
chr12_-_56121580 0.31 ENST00000550776.1
CD63
CD63 molecule
chr4_+_187148556 0.31 ENST00000264690.6
ENST00000446598.2
ENST00000414291.1
ENST00000513864.1
KLKB1
kallikrein B, plasma (Fletcher factor) 1
chr14_+_74111578 0.31 ENST00000554113.1
ENST00000555631.2
ENST00000553645.2
ENST00000311089.3
ENST00000555919.3
ENST00000554339.1
ENST00000554871.1
DNAL1
dynein, axonemal, light chain 1
chr11_-_62607036 0.31 ENST00000311713.7
ENST00000278856.4
WDR74
WD repeat domain 74
chr19_+_1077393 0.31 ENST00000590577.1
HMHA1
histocompatibility (minor) HA-1
chr3_-_178976996 0.30 ENST00000485523.1
KCNMB3
potassium large conductance calcium-activated channel, subfamily M beta member 3
chr9_+_125512019 0.29 ENST00000373684.1
ENST00000304720.2
OR1L6
olfactory receptor, family 1, subfamily L, member 6
chr2_+_234580499 0.28 ENST00000354728.4
UGT1A9
UDP glucuronosyltransferase 1 family, polypeptide A9
chr9_-_39288092 0.28 ENST00000323947.7
ENST00000297668.6
ENST00000377656.2
ENST00000377659.1
CNTNAP3
contactin associated protein-like 3
chr2_-_217560248 0.28 ENST00000233813.4
IGFBP5
insulin-like growth factor binding protein 5
chr14_+_21785693 0.28 ENST00000382933.4
ENST00000557351.1
RPGRIP1
retinitis pigmentosa GTPase regulator interacting protein 1
chr6_-_32821599 0.28 ENST00000354258.4
TAP1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr2_+_234580525 0.28 ENST00000609637.1
UGT1A1
UDP glucuronosyltransferase 1 family, polypeptide A8
chr8_-_20161466 0.27 ENST00000381569.1
LZTS1
leucine zipper, putative tumor suppressor 1
chr2_+_149974684 0.27 ENST00000450639.1
LYPD6B
LY6/PLAUR domain containing 6B
chr12_+_57849048 0.26 ENST00000266646.2
INHBE
inhibin, beta E
chr5_-_174871136 0.26 ENST00000393752.2
DRD1
dopamine receptor D1
chr19_-_10491234 0.26 ENST00000524462.1
ENST00000531836.1
ENST00000525621.1
TYK2
tyrosine kinase 2
chr4_-_71532207 0.26 ENST00000543780.1
ENST00000391614.3
IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr10_-_1071796 0.25 ENST00000277517.1
IDI2
isopentenyl-diphosphate delta isomerase 2
chr3_-_61237050 0.25 ENST00000476844.1
ENST00000488467.1
ENST00000492590.1
ENST00000468189.1
FHIT
fragile histidine triad
chr12_+_110011571 0.25 ENST00000539696.1
ENST00000228510.3
ENST00000392727.3
MVK
mevalonate kinase
chr20_+_34679725 0.25 ENST00000432589.1
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr3_+_148447887 0.25 ENST00000475347.1
ENST00000474935.1
ENST00000461609.1
AGTR1
angiotensin II receptor, type 1
chr2_-_133429091 0.24 ENST00000345008.6
LYPD1
LY6/PLAUR domain containing 1
chr10_+_94608218 0.24 ENST00000371543.1
EXOC6
exocyst complex component 6
chr2_-_27545921 0.24 ENST00000402310.1
ENST00000405983.1
ENST00000403262.2
ENST00000428910.1
ENST00000402722.1
ENST00000399052.4
ENST00000380044.1
ENST00000405076.1
MPV17
MpV17 mitochondrial inner membrane protein
chr10_-_44144152 0.24 ENST00000395797.1
ZNF32
zinc finger protein 32
chr15_-_59665062 0.24 ENST00000288235.4
MYO1E
myosin IE
chr10_+_94608245 0.23 ENST00000443748.2
ENST00000260762.6
EXOC6
exocyst complex component 6
chr15_+_79603479 0.23 ENST00000424155.2
ENST00000536821.1
TMED3
transmembrane emp24 protein transport domain containing 3
chr19_-_42931567 0.23 ENST00000244289.4
LIPE
lipase, hormone-sensitive
chr19_+_55385731 0.23 ENST00000469767.1
ENST00000355524.3
ENST00000391725.3
ENST00000345937.4
ENST00000353758.4
ENST00000359272.4
ENST00000391723.3
ENST00000391724.3
FCAR
Fc fragment of IgA, receptor for
chr4_+_156824840 0.23 ENST00000536354.2
TDO2
tryptophan 2,3-dioxygenase
chr6_+_31514622 0.23 ENST00000376146.4
NFKBIL1
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
chr7_+_99971129 0.22 ENST00000394000.2
ENST00000350573.2
PILRA
paired immunoglobin-like type 2 receptor alpha
chr6_-_52628271 0.22 ENST00000493422.1
GSTA2
glutathione S-transferase alpha 2
chr11_+_327171 0.22 ENST00000534483.1
ENST00000524824.1
ENST00000531076.1
RP11-326C3.12
RP11-326C3.12
chr1_-_231560790 0.21 ENST00000366641.3
EGLN1
egl-9 family hypoxia-inducible factor 1
chr16_+_83932684 0.21 ENST00000262430.4
MLYCD
malonyl-CoA decarboxylase
chr11_+_4673716 0.21 ENST00000530215.1
OR51E1
olfactory receptor, family 51, subfamily E, member 1
chr11_+_7506713 0.21 ENST00000329293.3
ENST00000534244.1
OLFML1
olfactomedin-like 1
chr5_-_135290651 0.21 ENST00000522943.1
ENST00000514447.2
LECT2
leukocyte cell-derived chemotaxin 2
chr6_+_32146268 0.21 ENST00000427134.2
RNF5
ring finger protein 5, E3 ubiquitin protein ligase
chr15_-_50411412 0.21 ENST00000284509.6
ATP8B4
ATPase, class I, type 8B, member 4
chr1_-_153935791 0.21 ENST00000429040.1
SLC39A1
solute carrier family 39 (zinc transporter), member 1
chr1_-_155959280 0.20 ENST00000495070.2
ARHGEF2
Rho/Rac guanine nucleotide exchange factor (GEF) 2
chr5_+_35617940 0.20 ENST00000282469.6
ENST00000509059.1
ENST00000356031.3
ENST00000510777.1
SPEF2
sperm flagellar 2
chr18_-_48351743 0.20 ENST00000588444.1
ENST00000256425.2
ENST00000428869.2
MRO
maestro
chr6_-_52668605 0.20 ENST00000334575.5
GSTA1
glutathione S-transferase alpha 1
chr11_-_327537 0.20 ENST00000602735.1
IFITM3
interferon induced transmembrane protein 3
chr19_+_39936267 0.19 ENST00000359191.6
SUPT5H
suppressor of Ty 5 homolog (S. cerevisiae)
chr11_+_65082289 0.19 ENST00000279249.2
CDC42EP2
CDC42 effector protein (Rho GTPase binding) 2
chr9_-_130679257 0.19 ENST00000361444.3
ENST00000335791.5
ENST00000343609.2
ST6GALNAC4
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
chr15_-_78592053 0.18 ENST00000267973.2
WDR61
WD repeat domain 61
chr16_-_67360662 0.18 ENST00000304372.5
KCTD19
potassium channel tetramerization domain containing 19
chr2_-_166060571 0.18 ENST00000360093.3
SCN3A
sodium channel, voltage-gated, type III, alpha subunit
chr4_-_46911223 0.18 ENST00000396533.1
COX7B2
cytochrome c oxidase subunit VIIb2
chr1_-_38230738 0.18 ENST00000427468.2
ENST00000373048.4
ENST00000319637.6
EPHA10
EPH receptor A10
chr11_+_7506837 0.18 ENST00000528758.1
OLFML1
olfactomedin-like 1
chr14_+_24641820 0.18 ENST00000560501.1
REC8
REC8 meiotic recombination protein
chr19_-_10491130 0.18 ENST00000530829.1
ENST00000529370.1
TYK2
tyrosine kinase 2
chr17_-_41132410 0.17 ENST00000409446.3
ENST00000453594.1
ENST00000409399.1
ENST00000421990.2
PTGES3L
PTGES3L-AARSD1
prostaglandin E synthase 3 (cytosolic)-like
PTGES3L-AARSD1 readthrough
chr2_+_96331830 0.17 ENST00000425887.2
AC008268.1
AC008268.1
chr3_+_122103014 0.17 ENST00000232125.5
ENST00000477892.1
ENST00000469967.1
FAM162A
family with sequence similarity 162, member A
chr17_-_1419914 0.17 ENST00000397335.3
ENST00000574561.1
INPP5K
inositol polyphosphate-5-phosphatase K
chr3_-_46068969 0.17 ENST00000542109.1
ENST00000395946.2
XCR1
chemokine (C motif) receptor 1
chr19_+_9296279 0.17 ENST00000344248.2
OR7D2
olfactory receptor, family 7, subfamily D, member 2
chr22_+_17956618 0.17 ENST00000262608.8
CECR2
cat eye syndrome chromosome region, candidate 2
chr19_+_39936186 0.17 ENST00000432763.2
ENST00000402194.2
ENST00000601515.1
SUPT5H
suppressor of Ty 5 homolog (S. cerevisiae)
chr19_-_47291843 0.16 ENST00000542575.2
SLC1A5
solute carrier family 1 (neutral amino acid transporter), member 5
chr21_+_47013566 0.16 ENST00000441095.1
ENST00000424569.1
AL133493.2
AL133493.2
chr22_-_42915788 0.16 ENST00000323013.6
RRP7A
ribosomal RNA processing 7 homolog A (S. cerevisiae)
chr12_+_124155652 0.16 ENST00000426174.2
ENST00000303372.5
TCTN2
tectonic family member 2
chr6_+_126661253 0.16 ENST00000368326.1
ENST00000368325.1
ENST00000368328.4
CENPW
centromere protein W
chr2_-_26569611 0.16 ENST00000541401.1
ENST00000433584.1
ENST00000333478.6
GPR113
G protein-coupled receptor 113
chr11_-_8285405 0.16 ENST00000335790.3
ENST00000534484.1
LMO1
LIM domain only 1 (rhombotin 1)
chr2_-_166060552 0.16 ENST00000283254.7
ENST00000453007.1
SCN3A
sodium channel, voltage-gated, type III, alpha subunit
chr17_-_66951382 0.16 ENST00000586539.1
ABCA8
ATP-binding cassette, sub-family A (ABC1), member 8
chr16_+_84801852 0.16 ENST00000569925.1
ENST00000567526.1
USP10
ubiquitin specific peptidase 10
chr21_-_15918618 0.16 ENST00000400564.1
ENST00000400566.1
SAMSN1
SAM domain, SH3 domain and nuclear localization signals 1
chr12_-_70093111 0.15 ENST00000548658.1
ENST00000476098.1
ENST00000331471.4
ENST00000393365.1
BEST3
bestrophin 3
chr5_-_137610300 0.15 ENST00000274721.3
GFRA3
GDNF family receptor alpha 3
chr9_-_16276311 0.15 ENST00000380685.1
C9orf92
chromosome 9 open reading frame 92
chr9_+_134378289 0.15 ENST00000423007.1
ENST00000404875.2
ENST00000441334.1
ENST00000341012.7
ENST00000372228.3
ENST00000402686.3
ENST00000419118.2
ENST00000541219.1
ENST00000354713.4
ENST00000418774.1
ENST00000415075.1
ENST00000448212.1
ENST00000430619.1
POMT1
protein-O-mannosyltransferase 1
chr1_-_153085984 0.15 ENST00000468739.1
SPRR2F
small proline-rich protein 2F
chr1_-_11865351 0.14 ENST00000413656.1
ENST00000376585.1
ENST00000423400.1
ENST00000431243.1
MTHFR
methylenetetrahydrofolate reductase (NAD(P)H)
chr14_+_70233810 0.14 ENST00000394366.2
ENST00000553548.1
ENST00000553369.1
ENST00000557154.1
ENST00000451983.2
ENST00000553635.1
SRSF5
serine/arginine-rich splicing factor 5
chr14_-_50087312 0.14 ENST00000298289.6
RPL36AL
ribosomal protein L36a-like
chr2_+_55459495 0.14 ENST00000272317.6
ENST00000449323.1
RPS27A
ribosomal protein S27a
chr17_+_39411636 0.14 ENST00000394008.1
KRTAP9-9
keratin associated protein 9-9
chr6_+_160542821 0.14 ENST00000366963.4
SLC22A1
solute carrier family 22 (organic cation transporter), member 1
chr16_-_30381580 0.13 ENST00000409939.3
TBC1D10B
TBC1 domain family, member 10B
chr18_+_55018044 0.13 ENST00000324000.3
ST8SIA3
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chr4_-_48908805 0.13 ENST00000273860.4
OCIAD2
OCIA domain containing 2
chr5_+_175740083 0.13 ENST00000332772.4
SIMC1
SUMO-interacting motifs containing 1
chr8_-_36636676 0.13 ENST00000524132.1
ENST00000519451.1
RP11-962G15.1
RP11-962G15.1
chr4_-_89442940 0.13 ENST00000527353.1
PIGY
phosphatidylinositol glycan anchor biosynthesis, class Y
chr3_+_108541545 0.13 ENST00000295756.6
TRAT1
T cell receptor associated transmembrane adaptor 1
chr11_+_71276609 0.13 ENST00000398531.1
ENST00000376536.4
KRTAP5-10
keratin associated protein 5-10
chr1_+_162351503 0.13 ENST00000458626.2
C1orf226
chromosome 1 open reading frame 226
chr8_-_72274095 0.12 ENST00000303824.7
EYA1
eyes absent homolog 1 (Drosophila)
chr10_+_71561704 0.12 ENST00000520267.1
COL13A1
collagen, type XIII, alpha 1
chr1_+_94798754 0.12 ENST00000418242.1
RP11-148B18.3
RP11-148B18.3
chr16_+_3062457 0.12 ENST00000445369.2
CLDN9
claudin 9
chr3_+_108541608 0.12 ENST00000426646.1
TRAT1
T cell receptor associated transmembrane adaptor 1
chr12_-_70093162 0.12 ENST00000551160.1
BEST3
bestrophin 3
chr15_-_52483566 0.12 ENST00000261837.7
GNB5
guanine nucleotide binding protein (G protein), beta 5
chr17_+_38465441 0.12 ENST00000577646.1
ENST00000254066.5
RARA
retinoic acid receptor, alpha
chr5_+_140535577 0.12 ENST00000539533.1
PCDHB17
Protocadherin-psi1; Uncharacterized protein
chr17_-_28661065 0.12 ENST00000328886.4
ENST00000538566.2
TMIGD1
transmembrane and immunoglobulin domain containing 1
chr12_-_5849134 0.11 ENST00000545860.1
ANO2
anoctamin 2
chr9_-_113100088 0.11 ENST00000374510.4
ENST00000423740.2
ENST00000374511.3
ENST00000374507.4
TXNDC8
thioredoxin domain containing 8 (spermatozoa)
chr9_+_35805527 0.11 ENST00000421267.1
NPR2
natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)
chr5_-_137610254 0.11 ENST00000378362.3
GFRA3
GDNF family receptor alpha 3
chr8_-_7243080 0.11 ENST00000400156.4
ZNF705G
zinc finger protein 705G
chr12_-_8765446 0.10 ENST00000537228.1
ENST00000229335.6
AICDA
activation-induced cytidine deaminase
chr6_+_52285046 0.10 ENST00000371068.5
EFHC1
EF-hand domain (C-terminal) containing 1
chr8_-_72268889 0.10 ENST00000388742.4
EYA1
eyes absent homolog 1 (Drosophila)
chrX_-_54824673 0.10 ENST00000218436.6
ITIH6
inter-alpha-trypsin inhibitor heavy chain family, member 6
chr4_+_120056939 0.10 ENST00000307128.5
MYOZ2
myozenin 2
chr19_-_14945933 0.10 ENST00000322301.3
OR7A5
olfactory receptor, family 7, subfamily A, member 5
chr7_+_127527965 0.10 ENST00000486037.1
SND1
staphylococcal nuclease and tudor domain containing 1
chr6_-_55443831 0.10 ENST00000428842.1
ENST00000358072.5
ENST00000508459.1
HMGCLL1
3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1
chr19_-_10679644 0.10 ENST00000393599.2
CDKN2D
cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
chr20_+_17949724 0.10 ENST00000377704.4
MGME1
mitochondrial genome maintenance exonuclease 1
chr1_-_110613276 0.10 ENST00000369792.4
ALX3
ALX homeobox 3
chr11_-_10590238 0.10 ENST00000256178.3
LYVE1
lymphatic vessel endothelial hyaluronan receptor 1
chr12_+_16500571 0.10 ENST00000543076.1
ENST00000396210.3
MGST1
microsomal glutathione S-transferase 1
chr22_-_41258074 0.10 ENST00000307221.4
DNAJB7
DnaJ (Hsp40) homolog, subfamily B, member 7
chr4_-_6202291 0.10 ENST00000282924.5
JAKMIP1
janus kinase and microtubule interacting protein 1
chrX_+_65382381 0.09 ENST00000519389.1
HEPH
hephaestin
chrX_+_135570046 0.09 ENST00000370648.3
BRS3
bombesin-like receptor 3
chr1_+_248223984 0.09 ENST00000359959.3
OR2L3
olfactory receptor, family 2, subfamily L, member 3

Network of associatons between targets according to the STRING database.

First level regulatory network of TBX3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.4 GO:0061143 alveolar primary septum development(GO:0061143)
0.2 3.0 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.2 0.8 GO:0002384 hepatic immune response(GO:0002384) response to prolactin(GO:1990637)
0.2 0.5 GO:0001994 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
0.2 0.5 GO:0048250 mitochondrial iron ion transport(GO:0048250)
0.1 0.3 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.1 0.3 GO:1904204 regulation of skeletal muscle hypertrophy(GO:1904204)
0.1 1.2 GO:0019344 cysteine biosynthetic process(GO:0019344)
0.1 1.4 GO:0035826 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.1 0.3 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541) positive regulation of fibrinolysis(GO:0051919)
0.1 0.4 GO:0003330 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.1 0.4 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.1 0.2 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.1 0.3 GO:0046967 cytosol to ER transport(GO:0046967)
0.1 0.3 GO:0050993 dimethylallyl diphosphate biosynthetic process(GO:0050992) dimethylallyl diphosphate metabolic process(GO:0050993)
0.1 0.2 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.1 0.6 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 0.2 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.1 0.3 GO:0070980 biphenyl catabolic process(GO:0070980)
0.1 0.6 GO:0046959 habituation(GO:0046959)
0.1 0.2 GO:0030806 negative regulation of cyclic nucleotide catabolic process(GO:0030806) negative regulation of cAMP catabolic process(GO:0030821) negative regulation of purine nucleotide catabolic process(GO:0033122)
0.1 0.2 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.0 0.3 GO:0051552 flavone metabolic process(GO:0051552)
0.0 0.2 GO:2001160 regulation of histone H3-K79 methylation(GO:2001160) positive regulation of histone H3-K79 methylation(GO:2001162)
0.0 0.2 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.0 0.2 GO:0036115 fatty-acyl-CoA catabolic process(GO:0036115)
0.0 0.2 GO:0036229 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.0 0.4 GO:0032096 negative regulation of response to food(GO:0032096) negative regulation of appetite(GO:0032099)
0.0 0.5 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.3 GO:2000809 regulation of postsynaptic density protein 95 clustering(GO:1902897) positive regulation of synaptic vesicle clustering(GO:2000809)
0.0 0.2 GO:1904100 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.0 0.2 GO:0035166 post-embryonic hemopoiesis(GO:0035166)
0.0 0.1 GO:0070829 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.0 0.2 GO:2001151 regulation of renal water transport(GO:2001151) positive regulation of renal water transport(GO:2001153)
0.0 0.2 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 0.1 GO:0048241 epinephrine transport(GO:0048241)
0.0 3.2 GO:0042246 tissue regeneration(GO:0042246)
0.0 0.3 GO:1901748 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.0 0.1 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.0 0.1 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.0 0.2 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 0.6 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.1 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.0 0.3 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.0 0.2 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.0 0.4 GO:0039692 single stranded viral RNA replication via double stranded DNA intermediate(GO:0039692)
0.0 0.1 GO:0030920 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.0 1.0 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0 0.1 GO:0009972 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.0 0.7 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.0 0.8 GO:0051281 positive regulation of release of sequestered calcium ion into cytosol(GO:0051281)
0.0 0.1 GO:0030573 bile acid catabolic process(GO:0030573)
0.0 0.1 GO:0060283 negative regulation of oocyte development(GO:0060283) negative regulation of oocyte maturation(GO:1900194)
0.0 0.1 GO:0008343 adult feeding behavior(GO:0008343)
0.0 0.5 GO:0090022 regulation of neutrophil chemotaxis(GO:0090022)
0.0 0.0 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.0 0.4 GO:1901663 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.1 GO:1902161 positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)
0.0 0.1 GO:0048102 autophagic cell death(GO:0048102)
0.0 1.3 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.2 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.0 0.1 GO:0060084 synaptic transmission involved in micturition(GO:0060084)
0.0 0.2 GO:0072520 seminiferous tubule development(GO:0072520)
0.0 0.5 GO:0030252 growth hormone secretion(GO:0030252)
0.0 0.4 GO:1901685 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.0 0.2 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.2 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.1 GO:0035803 egg coat formation(GO:0035803)
0.0 0.2 GO:1901386 negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.0 0.2 GO:0032836 glomerular basement membrane development(GO:0032836)
0.0 0.0 GO:0046416 D-amino acid metabolic process(GO:0046416)
0.0 0.4 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.0 0.5 GO:0030262 apoptotic nuclear changes(GO:0030262)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.0 GO:0005577 fibrinogen complex(GO:0005577)
0.2 0.8 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 1.1 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 1.4 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.1 0.4 GO:0032044 DSIF complex(GO:0032044)
0.1 0.2 GO:0030936 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.0 0.2 GO:0055087 Ski complex(GO:0055087)
0.0 0.3 GO:0042825 TAP complex(GO:0042825)
0.0 0.7 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.3 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.0 0.2 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.0 0.3 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.5 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.1 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 0.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.3 GO:0005916 fascia adherens(GO:0005916) catenin complex(GO:0016342)
0.0 0.5 GO:0005685 U1 snRNP(GO:0005685)
0.0 0.5 GO:0070069 cytochrome complex(GO:0070069)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0004947 bradykinin receptor activity(GO:0004947)
0.2 0.5 GO:0050135 NAD(P)+ nucleosidase activity(GO:0050135)
0.1 0.3 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.1 0.5 GO:0004936 alpha-adrenergic receptor activity(GO:0004936)
0.1 1.5 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.1 0.2 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.1 0.8 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.1 0.2 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.1 0.2 GO:0019862 IgA binding(GO:0019862)
0.1 0.5 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.1 0.5 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.1 0.3 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.1 0.3 GO:0004452 isopentenyl-diphosphate delta-isomerase activity(GO:0004452)
0.1 0.2 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 2.4 GO:0051183 vitamin transporter activity(GO:0051183)
0.0 0.2 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.2 GO:0004419 hydroxymethylglutaryl-CoA lyase activity(GO:0004419)
0.0 0.3 GO:0046979 TAP2 binding(GO:0046979)
0.0 0.2 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0 0.1 GO:0005277 acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375)
0.0 1.1 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.1 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.4 GO:0005131 growth hormone receptor binding(GO:0005131)
0.0 0.1 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.0 0.6 GO:0008430 selenium binding(GO:0008430)
0.0 0.2 GO:0051373 FATZ binding(GO:0051373)
0.0 0.3 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.2 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.3 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.3 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.3 GO:0099602 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 0.2 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.9 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.7 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.1 GO:1990190 peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.0 0.5 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 0.6 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 3.1 GO:0051087 chaperone binding(GO:0051087)
0.0 0.2 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.2 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.2 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.5 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.0 0.1 GO:0047787 delta4-3-oxosteroid 5beta-reductase activity(GO:0047787)
0.0 0.4 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.7 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.1 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.1 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.0 0.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.1 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.0 0.2 GO:0042910 xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.0 0.1 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 1.3 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.3 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.0 0.3 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.2 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.1 GO:0015056 corticotrophin-releasing factor receptor activity(GO:0015056)
0.0 0.5 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.2 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.1 GO:0032190 acrosin binding(GO:0032190)
0.0 0.3 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 3.0 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.8 ST STAT3 PATHWAY STAT3 Pathway
0.0 0.4 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.0 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 0.6 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 1.2 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 1.7 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.8 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.3 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.8 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.6 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.2 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.3 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.4 REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.0 0.5 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.8 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.6 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.3 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation