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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for TBX4

Z-value: 0.85

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Transcription factors associated with TBX4

Gene Symbol Gene ID Gene Info
TBX4
ENSG00000121075.5 T-box transcription factor 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TBX4hg19_v2_chr17_+_59529743_595297980.331.5e-01Click!

Activity profile of TBX4 motif

Sorted Z-values of TBX4 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr9_-_75567962 2.40 ENST00000297785.3
ENST00000376939.1
ALDH1A1
aldehyde dehydrogenase 1 family, member A1
chr9_+_40028620 1.05 ENST00000426179.1
AL353791.1
AL353791.1
chr10_+_31608054 0.89 ENST00000320985.10
ENST00000361642.5
ENST00000560721.2
ENST00000558440.1
ENST00000424869.1
ENST00000542815.3
ZEB1
zinc finger E-box binding homeobox 1
chr7_+_107220899 0.84 ENST00000379117.2
ENST00000473124.1
BCAP29
B-cell receptor-associated protein 29
chr2_-_175870085 0.82 ENST00000409156.3
CHN1
chimerin 1
chr20_-_22565101 0.80 ENST00000419308.2
FOXA2
forkhead box A2
chr2_-_175869936 0.79 ENST00000409900.3
CHN1
chimerin 1
chr5_+_74807581 0.79 ENST00000241436.4
ENST00000352007.5
POLK
polymerase (DNA directed) kappa
chr7_+_107220660 0.76 ENST00000465919.1
ENST00000445771.2
ENST00000479917.1
ENST00000421217.1
ENST00000457837.1
BCAP29
B-cell receptor-associated protein 29
chr2_+_29033682 0.75 ENST00000379579.4
ENST00000334056.5
ENST00000449210.1
SPDYA
speedy/RINGO cell cycle regulator family member A
chr12_-_120241187 0.75 ENST00000392520.2
CIT
citron (rho-interacting, serine/threonine kinase 21)
chr1_+_95582881 0.74 ENST00000370203.4
ENST00000456991.1
TMEM56
transmembrane protein 56
chr2_-_61697862 0.72 ENST00000398571.2
USP34
ubiquitin specific peptidase 34
chr3_+_142315225 0.70 ENST00000457734.2
ENST00000483373.1
ENST00000475296.1
ENST00000495744.1
ENST00000476044.1
ENST00000461644.1
PLS1
plastin 1
chr12_-_90024360 0.69 ENST00000393164.2
ATP2B1
ATPase, Ca++ transporting, plasma membrane 1
chr11_+_86511549 0.68 ENST00000533902.2
PRSS23
protease, serine, 23
chr3_+_142315294 0.67 ENST00000464320.1
PLS1
plastin 1
chr14_+_53196872 0.65 ENST00000442123.2
ENST00000354586.4
STYX
serine/threonine/tyrosine interacting protein
chr7_+_143013198 0.63 ENST00000343257.2
CLCN1
chloride channel, voltage-sensitive 1
chr10_+_45406627 0.62 ENST00000389583.4
TMEM72
transmembrane protein 72
chr11_-_85430088 0.62 ENST00000533057.1
ENST00000533892.1
SYTL2
synaptotagmin-like 2
chr11_-_85430204 0.60 ENST00000389958.3
ENST00000527794.1
SYTL2
synaptotagmin-like 2
chr10_-_16563870 0.60 ENST00000298943.3
C1QL3
complement component 1, q subcomponent-like 3
chr18_-_56296182 0.58 ENST00000361673.3
ALPK2
alpha-kinase 2
chr11_-_85430163 0.56 ENST00000529581.1
ENST00000533577.1
SYTL2
synaptotagmin-like 2
chr7_-_27142290 0.56 ENST00000222718.5
HOXA2
homeobox A2
chrX_-_133930285 0.51 ENST00000486347.1
ENST00000343004.5
FAM122B
family with sequence similarity 122B
chr8_-_99954788 0.51 ENST00000523601.1
STK3
serine/threonine kinase 3
chr16_+_57139933 0.51 ENST00000566259.1
CPNE2
copine II
chr5_+_68788594 0.50 ENST00000396442.2
ENST00000380766.2
OCLN
occludin
chr2_-_111291587 0.49 ENST00000437167.1
RGPD6
RANBP2-like and GRIP domain containing 6
chr5_+_133861339 0.47 ENST00000282605.4
ENST00000361895.2
ENST00000402835.1
PHF15
jade family PHD finger 2
chrX_+_16804544 0.47 ENST00000380122.5
ENST00000398155.4
TXLNG
taxilin gamma
chrX_+_46772065 0.47 ENST00000455411.1
PHF16
jade family PHD finger 3
chrX_-_19689106 0.45 ENST00000379716.1
SH3KBP1
SH3-domain kinase binding protein 1
chr2_+_61108650 0.45 ENST00000295025.8
REL
v-rel avian reticuloendotheliosis viral oncogene homolog
chr8_-_95907423 0.44 ENST00000396133.3
ENST00000308108.4
CCNE2
cyclin E2
chr1_+_26737292 0.44 ENST00000254231.4
LIN28A
lin-28 homolog A (C. elegans)
chr11_-_115127611 0.43 ENST00000545094.1
CADM1
cell adhesion molecule 1
chr14_+_90864504 0.42 ENST00000544280.2
CALM1
calmodulin 1 (phosphorylase kinase, delta)
chr2_-_42160486 0.42 ENST00000427054.1
AC104654.2
AC104654.2
chr12_+_57853918 0.42 ENST00000532291.1
ENST00000543426.1
ENST00000228682.2
ENST00000546141.1
GLI1
GLI family zinc finger 1
chr5_-_74807418 0.41 ENST00000405807.4
ENST00000261415.7
COL4A3BP
collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
chr15_-_83474806 0.41 ENST00000541889.1
ENST00000334574.8
ENST00000561368.1
FSD2
fibronectin type III and SPRY domain containing 2
chr12_+_65672702 0.41 ENST00000538045.1
ENST00000535239.1
MSRB3
methionine sulfoxide reductase B3
chr12_+_57854274 0.41 ENST00000528432.1
GLI1
GLI family zinc finger 1
chr10_+_94833642 0.40 ENST00000224356.4
ENST00000394139.1
CYP26A1
cytochrome P450, family 26, subfamily A, polypeptide 1
chr5_+_74807886 0.39 ENST00000514296.1
POLK
polymerase (DNA directed) kappa
chr11_+_114271251 0.39 ENST00000375490.5
RBM7
RNA binding motif protein 7
chr2_-_37458749 0.39 ENST00000234170.5
CEBPZ
CCAAT/enhancer binding protein (C/EBP), zeta
chr11_+_111749650 0.39 ENST00000528125.1
C11orf1
chromosome 11 open reading frame 1
chr1_+_154378049 0.38 ENST00000512471.1
IL6R
interleukin 6 receptor
chr2_+_154728426 0.38 ENST00000392825.3
ENST00000434213.1
GALNT13
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 13 (GalNAc-T13)
chr11_+_111750206 0.38 ENST00000530214.1
ENST00000530799.1
C11orf1
chromosome 11 open reading frame 1
chr4_+_140222609 0.38 ENST00000296543.5
ENST00000398947.1
NAA15
N(alpha)-acetyltransferase 15, NatA auxiliary subunit
chr1_-_11907829 0.37 ENST00000376480.3
NPPA
natriuretic peptide A
chr11_+_122709200 0.36 ENST00000227348.4
CRTAM
cytotoxic and regulatory T cell molecule
chr15_+_36994210 0.36 ENST00000562489.1
C15orf41
chromosome 15 open reading frame 41
chr11_-_85779971 0.36 ENST00000393346.3
PICALM
phosphatidylinositol binding clathrin assembly protein
chrX_+_46771711 0.36 ENST00000424392.1
ENST00000397189.1
PHF16
jade family PHD finger 3
chr7_-_105319536 0.35 ENST00000477775.1
ATXN7L1
ataxin 7-like 1
chr2_-_61108449 0.34 ENST00000439412.1
ENST00000452343.1
AC010733.4
AC010733.4
chr7_-_150675372 0.34 ENST00000262186.5
KCNH2
potassium voltage-gated channel, subfamily H (eag-related), member 2
chr2_+_172864490 0.33 ENST00000315796.4
METAP1D
methionyl aminopeptidase type 1D (mitochondrial)
chr5_-_60240858 0.33 ENST00000426742.2
ENST00000265038.5
ENST00000543101.1
ENST00000439176.1
ERCC8
excision repair cross-complementing rodent repair deficiency, complementation group 8
chr11_+_86511569 0.33 ENST00000441050.1
PRSS23
protease, serine, 23
chr4_-_114438763 0.33 ENST00000509594.1
CAMK2D
calcium/calmodulin-dependent protein kinase II delta
chr11_-_111749878 0.33 ENST00000260257.4
FDXACB1
ferredoxin-fold anticodon binding domain containing 1
chr3_-_197024394 0.32 ENST00000434148.1
ENST00000412364.2
ENST00000436682.1
ENST00000456699.2
ENST00000392380.2
DLG1
discs, large homolog 1 (Drosophila)
chrX_+_123095546 0.32 ENST00000371157.3
ENST00000371145.3
ENST00000371144.3
STAG2
stromal antigen 2
chr20_+_11898507 0.31 ENST00000378226.2
BTBD3
BTB (POZ) domain containing 3
chr16_-_67965756 0.31 ENST00000571044.1
ENST00000571605.1
CTRL
chymotrypsin-like
chr11_-_125932685 0.31 ENST00000527967.1
CDON
cell adhesion associated, oncogene regulated
chr11_+_4116054 0.30 ENST00000423050.2
RRM1
ribonucleotide reductase M1
chr2_+_43864387 0.29 ENST00000282406.4
PLEKHH2
pleckstrin homology domain containing, family H (with MyTH4 domain) member 2
chr4_-_114682936 0.27 ENST00000454265.2
ENST00000429180.1
ENST00000418639.2
ENST00000394526.2
ENST00000296402.5
CAMK2D
calcium/calmodulin-dependent protein kinase II delta
chr17_-_8066843 0.27 ENST00000404970.3
VAMP2
vesicle-associated membrane protein 2 (synaptobrevin 2)
chr7_-_127032741 0.27 ENST00000393313.1
ENST00000265827.3
ENST00000434602.1
ZNF800
zinc finger protein 800
chr2_-_85895295 0.26 ENST00000428225.1
ENST00000519937.2
SFTPB
surfactant protein B
chrX_+_46771848 0.26 ENST00000218343.4
PHF16
jade family PHD finger 3
chr1_+_35734616 0.26 ENST00000441447.1
ZMYM4
zinc finger, MYM-type 4
chr16_+_2588012 0.26 ENST00000354836.5
ENST00000389224.3
PDPK1
3-phosphoinositide dependent protein kinase-1
chr22_-_41215328 0.26 ENST00000434185.1
ENST00000435456.2
SLC25A17
solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17
chr11_-_111749767 0.26 ENST00000542429.1
FDXACB1
ferredoxin-fold anticodon binding domain containing 1
chr7_-_76255444 0.26 ENST00000454397.1
POMZP3
POM121 and ZP3 fusion
chr16_+_67596310 0.26 ENST00000264010.4
ENST00000401394.1
CTCF
CCCTC-binding factor (zinc finger protein)
chr14_-_45603657 0.26 ENST00000396062.3
FKBP3
FK506 binding protein 3, 25kDa
chr11_+_111749942 0.25 ENST00000260276.3
C11orf1
chromosome 11 open reading frame 1
chr2_-_177684007 0.25 ENST00000451851.1
AC092162.1
AC092162.1
chr5_-_172756506 0.24 ENST00000265087.4
STC2
stanniocalcin 2
chr17_+_79031415 0.24 ENST00000572073.1
ENST00000573677.1
BAIAP2
BAI1-associated protein 2
chr5_+_56469843 0.24 ENST00000514387.2
GPBP1
GC-rich promoter binding protein 1
chr11_+_18344106 0.23 ENST00000534641.1
ENST00000525831.1
ENST00000265963.4
GTF2H1
general transcription factor IIH, polypeptide 1, 62kDa
chr2_+_62933001 0.23 ENST00000263991.5
ENST00000354487.3
EHBP1
EH domain binding protein 1
chr5_+_56469939 0.23 ENST00000506184.2
GPBP1
GC-rich promoter binding protein 1
chr11_-_62689046 0.22 ENST00000306960.3
ENST00000543973.1
CHRM1
cholinergic receptor, muscarinic 1
chr2_+_61108771 0.22 ENST00000394479.3
REL
v-rel avian reticuloendotheliosis viral oncogene homolog
chr4_-_114682597 0.22 ENST00000394524.3
CAMK2D
calcium/calmodulin-dependent protein kinase II delta
chr4_-_114682719 0.22 ENST00000394522.3
CAMK2D
calcium/calmodulin-dependent protein kinase II delta
chr22_-_42342733 0.21 ENST00000402420.1
CENPM
centromere protein M
chr11_+_18343800 0.21 ENST00000453096.2
GTF2H1
general transcription factor IIH, polypeptide 1, 62kDa
chr14_+_67291158 0.21 ENST00000555456.1
GPHN
gephyrin
chr12_-_116714564 0.21 ENST00000548743.1
MED13L
mediator complex subunit 13-like
chr5_-_78809950 0.21 ENST00000334082.6
HOMER1
homer homolog 1 (Drosophila)
chr2_+_62932779 0.20 ENST00000427809.1
ENST00000405482.1
ENST00000431489.1
EHBP1
EH domain binding protein 1
chr11_+_61447845 0.20 ENST00000257215.5
DAGLA
diacylglycerol lipase, alpha
chr2_+_103089756 0.20 ENST00000295269.4
SLC9A4
solute carrier family 9, subfamily A (NHE4, cation proton antiporter 4), member 4
chr2_+_37458928 0.19 ENST00000439218.1
ENST00000432075.1
NDUFAF7
NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
chr11_-_85430356 0.19 ENST00000526999.1
SYTL2
synaptotagmin-like 2
chr5_-_114515734 0.19 ENST00000514154.1
ENST00000282369.3
TRIM36
tripartite motif containing 36
chr22_-_41215291 0.19 ENST00000542412.1
ENST00000544408.1
SLC25A17
solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17
chr7_+_27282319 0.19 ENST00000222761.3
EVX1
even-skipped homeobox 1
chr17_+_30771279 0.19 ENST00000261712.3
ENST00000578213.1
ENST00000457654.2
ENST00000579451.1
PSMD11
proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr14_+_21467414 0.19 ENST00000554422.1
ENST00000298681.4
SLC39A2
solute carrier family 39 (zinc transporter), member 2
chr15_+_91449971 0.19 ENST00000557865.1
MAN2A2
mannosidase, alpha, class 2A, member 2
chr5_+_60241020 0.18 ENST00000511107.1
ENST00000502658.1
NDUFAF2
NADH dehydrogenase (ubiquinone) complex I, assembly factor 2
chr16_+_85645007 0.18 ENST00000405402.2
GSE1
Gse1 coiled-coil protein
chr1_+_114471972 0.18 ENST00000369559.4
ENST00000369554.2
HIPK1
homeodomain interacting protein kinase 1
chr11_+_114270752 0.18 ENST00000540163.1
RBM7
RNA binding motif protein 7
chrX_+_123095860 0.18 ENST00000428941.1
STAG2
stromal antigen 2
chr15_+_41913690 0.17 ENST00000563576.1
MGA
MGA, MAX dimerization protein
chr1_-_226076843 0.16 ENST00000272134.5
LEFTY1
left-right determination factor 1
chr21_+_30502806 0.16 ENST00000399928.1
ENST00000399926.1
MAP3K7CL
MAP3K7 C-terminal like
chrX_+_123095890 0.15 ENST00000435215.1
STAG2
stromal antigen 2
chr4_+_57371509 0.15 ENST00000360096.2
ARL9
ADP-ribosylation factor-like 9
chr17_-_39203519 0.14 ENST00000542137.1
ENST00000391419.3
KRTAP2-1
keratin associated protein 2-1
chr17_-_39222131 0.14 ENST00000394015.2
KRTAP2-4
keratin associated protein 2-4
chr1_-_37499726 0.14 ENST00000373091.3
ENST00000373093.4
GRIK3
glutamate receptor, ionotropic, kainate 3
chr1_-_111148241 0.14 ENST00000440270.1
KCNA2
potassium voltage-gated channel, shaker-related subfamily, member 2
chr2_+_37458776 0.14 ENST00000002125.4
ENST00000336237.6
ENST00000431821.1
NDUFAF7
NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
chr8_+_56014949 0.14 ENST00000327381.6
XKR4
XK, Kell blood group complex subunit-related family, member 4
chr1_-_85930246 0.13 ENST00000426972.3
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr2_+_202937972 0.13 ENST00000541917.1
ENST00000295844.3
AC079354.1
uncharacterized protein KIAA2012
chr2_-_219925189 0.13 ENST00000295731.6
IHH
indian hedgehog
chr15_+_89402148 0.13 ENST00000560601.1
ACAN
aggrecan
chr9_+_136399929 0.12 ENST00000393060.1
ADAMTSL2
ADAMTS-like 2
chr13_-_46543805 0.12 ENST00000378921.2
ZC3H13
zinc finger CCCH-type containing 13
chr13_-_52027134 0.12 ENST00000311234.4
ENST00000425000.1
ENST00000463928.1
ENST00000442263.3
ENST00000398119.2
INTS6
integrator complex subunit 6
chr2_-_160473114 0.12 ENST00000392783.2
BAZ2B
bromodomain adjacent to zinc finger domain, 2B
chr10_-_98945264 0.12 ENST00000314867.5
SLIT1
slit homolog 1 (Drosophila)
chr5_+_56469775 0.11 ENST00000424459.3
GPBP1
GC-rich promoter binding protein 1
chr9_-_74979420 0.11 ENST00000343431.2
ENST00000376956.3
ZFAND5
zinc finger, AN1-type domain 5
chr11_-_7847519 0.11 ENST00000328375.1
OR5P3
olfactory receptor, family 5, subfamily P, member 3
chr17_+_57970469 0.11 ENST00000443572.2
ENST00000406116.3
ENST00000225577.4
ENST00000393021.3
RPS6KB1
ribosomal protein S6 kinase, 70kDa, polypeptide 1
chr1_+_114471809 0.11 ENST00000426820.2
HIPK1
homeodomain interacting protein kinase 1
chr1_+_26737253 0.11 ENST00000326279.6
LIN28A
lin-28 homolog A (C. elegans)
chr11_-_18343669 0.11 ENST00000396253.3
ENST00000349215.3
ENST00000438420.2
HPS5
Hermansky-Pudlak syndrome 5
chr13_-_36429763 0.11 ENST00000379893.1
DCLK1
doublecortin-like kinase 1
chr17_+_35849937 0.10 ENST00000394389.4
DUSP14
dual specificity phosphatase 14
chr9_+_140032842 0.10 ENST00000371561.3
ENST00000315048.3
GRIN1
glutamate receptor, ionotropic, N-methyl D-aspartate 1
chr6_-_31080336 0.10 ENST00000259870.3
C6orf15
chromosome 6 open reading frame 15
chr8_+_95907993 0.10 ENST00000523378.1
NDUFAF6
NADH dehydrogenase (ubiquinone) complex I, assembly factor 6
chr11_+_17568920 0.10 ENST00000399391.2
OTOG
otogelin
chr1_-_1009683 0.10 ENST00000453464.2
RNF223
ring finger protein 223
chr5_-_34043310 0.09 ENST00000231338.7
C1QTNF3
C1q and tumor necrosis factor related protein 3
chr11_+_74660278 0.08 ENST00000263672.6
ENST00000530257.1
ENST00000526361.1
ENST00000532972.1
SPCS2
signal peptidase complex subunit 2 homolog (S. cerevisiae)
chr6_+_39760129 0.08 ENST00000274867.4
DAAM2
dishevelled associated activator of morphogenesis 2
chr10_+_7860460 0.08 ENST00000344293.5
TAF3
TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa
chr16_-_2205352 0.08 ENST00000563192.1
RP11-304L19.5
RP11-304L19.5
chrX_+_70443050 0.07 ENST00000361726.6
GJB1
gap junction protein, beta 1, 32kDa
chr9_-_74980113 0.07 ENST00000376962.5
ENST00000376960.4
ENST00000237937.3
ZFAND5
zinc finger, AN1-type domain 5
chr17_-_61996160 0.07 ENST00000458650.2
ENST00000351388.4
ENST00000323322.5
GH1
growth hormone 1
chr10_-_75226166 0.07 ENST00000544628.1
PPP3CB
protein phosphatase 3, catalytic subunit, beta isozyme
chr17_-_61996136 0.07 ENST00000342364.4
GH1
growth hormone 1
chr1_+_27114418 0.07 ENST00000078527.4
PIGV
phosphatidylinositol glycan anchor biosynthesis, class V
chr15_+_76016293 0.06 ENST00000332145.2
ODF3L1
outer dense fiber of sperm tails 3-like 1
chrX_+_123480194 0.06 ENST00000371139.4
SH2D1A
SH2 domain containing 1A
chr14_+_93897199 0.06 ENST00000553484.1
UNC79
unc-79 homolog (C. elegans)
chr3_+_137728842 0.06 ENST00000183605.5
CLDN18
claudin 18
chr22_+_40441456 0.05 ENST00000402203.1
TNRC6B
trinucleotide repeat containing 6B
chrM_+_10464 0.05 ENST00000361335.1
MT-ND4L
mitochondrially encoded NADH dehydrogenase 4L
chr12_-_53097247 0.05 ENST00000341809.3
ENST00000537195.1
KRT77
keratin 77
chr7_-_123673471 0.05 ENST00000455783.1
TMEM229A
transmembrane protein 229A
chr16_+_2587965 0.05 ENST00000342085.4
ENST00000566659.1
PDPK1
3-phosphoinositide dependent protein kinase-1
chr11_-_118972575 0.05 ENST00000432443.2
DPAGT1
dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)
chr14_+_93897272 0.05 ENST00000393151.2
UNC79
unc-79 homolog (C. elegans)
chr16_+_2587998 0.04 ENST00000441549.3
ENST00000268673.7
PDPK1
3-phosphoinositide dependent protein kinase-1
chr20_+_44657845 0.04 ENST00000243964.3
SLC12A5
solute carrier family 12 (potassium/chloride transporter), member 5
chr5_+_32712363 0.04 ENST00000507141.1
NPR3
natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)
chr3_-_133748758 0.04 ENST00000493729.1
SLCO2A1
solute carrier organic anion transporter family, member 2A1
chr6_+_79577189 0.04 ENST00000369940.2
IRAK1BP1
interleukin-1 receptor-associated kinase 1 binding protein 1
chr6_-_19804973 0.04 ENST00000457670.1
ENST00000607810.1
ENST00000606628.1
RP4-625H18.2
RP4-625H18.2
chr11_-_5248294 0.03 ENST00000335295.4
HBB
hemoglobin, beta
chr2_-_40680578 0.03 ENST00000455476.1
SLC8A1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr1_+_154377669 0.03 ENST00000368485.3
ENST00000344086.4
IL6R
interleukin 6 receptor
chr11_-_65629497 0.03 ENST00000532134.1
CFL1
cofilin 1 (non-muscle)
chr7_+_133261209 0.03 ENST00000545148.1
EXOC4
exocyst complex component 4
chr3_+_107364769 0.02 ENST00000449271.1
ENST00000425868.1
ENST00000449213.1
BBX
bobby sox homolog (Drosophila)
chr11_+_1940786 0.02 ENST00000278317.6
ENST00000381561.4
ENST00000381548.3
ENST00000360603.3
ENST00000381549.3
TNNT3
troponin T type 3 (skeletal, fast)
chr11_-_7818520 0.02 ENST00000329434.2
OR5P2
olfactory receptor, family 5, subfamily P, member 2
chr3_+_107364683 0.02 ENST00000413213.1
BBX
bobby sox homolog (Drosophila)
chr10_+_135050908 0.02 ENST00000325980.9
VENTX
VENT homeobox
chr3_-_133748913 0.02 ENST00000310926.4
SLCO2A1
solute carrier organic anion transporter family, member 2A1
chr7_-_28220354 0.02 ENST00000283928.5
JAZF1
JAZF zinc finger 1
chr6_-_19804877 0.01 ENST00000447250.1
RP4-625H18.2
RP4-625H18.2
chr3_+_167453026 0.01 ENST00000472941.1
SERPINI1
serpin peptidase inhibitor, clade I (neuroserpin), member 1
chr2_+_11696464 0.01 ENST00000234142.5
GREB1
growth regulation by estrogen in breast cancer 1
chr5_+_150040403 0.01 ENST00000517768.1
ENST00000297130.4
MYOZ3
myozenin 3
chr4_-_102268484 0.01 ENST00000394853.4
PPP3CA
protein phosphatase 3, catalytic subunit, alpha isozyme
chr20_+_2517253 0.01 ENST00000358864.1
TMC2
transmembrane channel-like 2

Network of associatons between targets according to the STRING database.

First level regulatory network of TBX4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.4 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.2 0.8 GO:0060032 notochord regression(GO:0060032)
0.2 0.8 GO:0045014 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.2 1.4 GO:1902896 terminal web assembly(GO:1902896)
0.2 0.6 GO:0035283 rhombomere 3 development(GO:0021569) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.1 0.4 GO:0043132 coenzyme A transport(GO:0015880) coenzyme A transmembrane transport(GO:0035349) NAD transport(GO:0043132) adenosine 3',5'-bisphosphate transmembrane transport(GO:0071106) AMP transport(GO:0080121)
0.1 1.6 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1 0.4 GO:0035621 ER to Golgi ceramide transport(GO:0035621)
0.1 2.0 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.1 0.3 GO:1902303 regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
0.1 0.4 GO:0002384 hepatic immune response(GO:0002384)
0.1 0.6 GO:0045204 MAPK export from nucleus(GO:0045204)
0.1 0.9 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.1 0.6 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.1 0.4 GO:0016103 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.1 0.7 GO:1903764 regulation of potassium ion export across plasma membrane(GO:1903764)
0.1 0.7 GO:1990034 cellular response to corticosterone stimulus(GO:0071386) calcium ion export from cell(GO:1990034)
0.1 0.4 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.1 0.4 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1 0.2 GO:0042040 molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.1 0.2 GO:0098917 retrograde trans-synaptic signaling(GO:0098917)
0.1 0.4 GO:0035803 egg coat formation(GO:0035803)
0.1 1.0 GO:1901725 regulation of histone deacetylase activity(GO:1901725) regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.1 0.5 GO:0010587 miRNA catabolic process(GO:0010587)
0.1 0.2 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.1 0.4 GO:1902962 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.0 0.2 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.0 0.6 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 0.7 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 0.3 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.0 0.6 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.1 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.0 0.4 GO:0002857 positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.0 0.6 GO:0060059 embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.0 0.1 GO:0043449 cellular alkene metabolic process(GO:0043449)
0.0 0.3 GO:1903593 eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil degranulation(GO:0043308) regulation of histamine secretion by mast cell(GO:1903593)
0.0 1.7 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.3 GO:0070602 regulation of centromeric sister chromatid cohesion(GO:0070602)
0.0 0.7 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.0 0.2 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.4 GO:0030091 protein repair(GO:0030091)
0.0 1.2 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.5 GO:0070673 response to interleukin-18(GO:0070673)
0.0 0.2 GO:1905232 cellular response to L-glutamate(GO:1905232)
0.0 0.3 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.0 0.1 GO:0021633 optic nerve structural organization(GO:0021633)
0.0 0.2 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 0.1 GO:0019566 arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373)
0.0 0.1 GO:0010536 positive regulation of activation of Janus kinase activity(GO:0010536)
0.0 0.7 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.0 0.7 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.4 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.2 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.1 GO:0060481 lobar bronchus epithelium development(GO:0060481)
0.0 0.7 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.2 GO:0043248 proteasome assembly(GO:0043248)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.4 GO:1990357 terminal web(GO:1990357)
0.1 0.6 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.1 0.4 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
0.1 0.4 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 0.3 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.1 0.4 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.1 0.3 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.7 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.4 GO:0031415 NatA complex(GO:0031415)
0.0 0.1 GO:0070195 growth hormone receptor complex(GO:0070195)
0.0 0.4 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.3 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.0 0.3 GO:0097486 multivesicular body lumen(GO:0097486)
0.0 0.1 GO:0031084 BLOC-2 complex(GO:0031084)
0.0 0.7 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.2 GO:0043196 varicosity(GO:0043196)
0.0 0.3 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.3 GO:0097025 lateral loop(GO:0043219) MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.2 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.8 GO:0097546 ciliary base(GO:0097546)
0.0 1.0 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.5 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.4 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.1 GO:0098839 postsynaptic density membrane(GO:0098839)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.4 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.1 0.4 GO:0071077 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.1 0.4 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
0.1 0.3 GO:0004676 3-phosphoinositide-dependent protein kinase activity(GO:0004676)
0.1 0.6 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.1 2.0 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.4 GO:0097001 ceramide binding(GO:0097001)
0.1 0.2 GO:0061598 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.1 0.4 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.1 0.4 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.1 1.0 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.1 GO:0005148 prolactin receptor binding(GO:0005148)
0.0 0.3 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.3 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.0 0.3 GO:0016728 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.2 GO:0004572 mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity(GO:0004572)
0.0 0.5 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.2 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 1.2 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.1 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.1 GO:0070052 collagen V binding(GO:0070052)
0.0 0.4 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.3 GO:0097016 L27 domain binding(GO:0097016)
0.0 1.6 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.3 GO:0032190 acrosin binding(GO:0032190)
0.0 0.6 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.4 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.1 GO:0050436 microfibril binding(GO:0050436)
0.0 0.1 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.0 0.7 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.1 GO:0016403 dimethylargininase activity(GO:0016403)
0.0 0.1 GO:0015277 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) kainate selective glutamate receptor activity(GO:0015277) G-protein coupled glutamate receptor activity(GO:0098988)
0.0 0.4 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.2 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.4 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.0 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 0.1 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.1 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.2 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.4 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.8 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID RHOA PATHWAY RhoA signaling pathway
0.0 1.0 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.4 ST STAT3 PATHWAY STAT3 Pathway
0.0 0.4 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.4 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.7 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 1.6 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.4 PID AP1 PATHWAY AP-1 transcription factor network
0.0 1.6 PID RAC1 REG PATHWAY Regulation of RAC1 activity

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.4 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 1.6 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.5 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.4 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.8 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.8 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.0 0.3 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS Genes involved in CREB phosphorylation through the activation of Ras
0.0 0.3 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.4 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.1 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.4 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.2 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin