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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for TBX5

Z-value: 0.45

Motif logo

Transcription factors associated with TBX5

Gene Symbol Gene ID Gene Info
ENSG00000089225.15 T-box transcription factor 5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TBX5hg19_v2_chr12_-_114843889_114843921-0.058.2e-01Click!

Activity profile of TBX5 motif

Sorted Z-values of TBX5 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr14_+_75746781 1.89 ENST00000555347.1
FBJ murine osteosarcoma viral oncogene homolog
chr14_+_75745477 1.08 ENST00000303562.4
ENST00000554617.1
ENST00000554212.1
ENST00000535987.1
ENST00000555242.1
FBJ murine osteosarcoma viral oncogene homolog
chr2_+_42275153 0.96 ENST00000294964.5
protein kinase domain containing, cytoplasmic
chr1_+_8378140 0.79 ENST00000377479.2
solute carrier family 45, member 1
chr22_-_51016846 0.72 ENST00000312108.7
ENST00000395650.2
carnitine palmitoyltransferase 1B (muscle)
chr17_-_26697304 0.72 ENST00000536498.1
vitronectin
chr14_-_37051798 0.69 ENST00000258829.5
NK2 homeobox 8
chr15_+_89182156 0.66 ENST00000379224.5
interferon stimulated exonuclease gene 20kDa
chr22_-_51016433 0.64 ENST00000405237.3
carnitine palmitoyltransferase 1B (muscle)
chr3_-_49726486 0.60 ENST00000449682.2
macrophage stimulating 1 (hepatocyte growth factor-like)
chr17_+_68165657 0.60 ENST00000243457.3
potassium inwardly-rectifying channel, subfamily J, member 2
chr15_+_89182178 0.58 ENST00000559876.1
interferon stimulated exonuclease gene 20kDa
chr16_-_2205352 0.57 ENST00000563192.1
RP11-304L19.5
chr19_+_54385439 0.54 ENST00000536044.1
ENST00000540413.1
ENST00000263431.3
ENST00000419486.1
protein kinase C, gamma
chr15_+_89181974 0.52 ENST00000306072.5
interferon stimulated exonuclease gene 20kDa
chr9_-_75567962 0.49 ENST00000297785.3
ENST00000376939.1
aldehyde dehydrogenase 1 family, member A1
chr2_-_42160486 0.49 ENST00000427054.1
AC104654.2
chr19_+_39786962 0.49 ENST00000333625.2
interferon, lambda 1
chr16_-_11350036 0.48 ENST00000332029.2
suppressor of cytokine signaling 1
chr17_+_77020224 0.45 ENST00000339142.2
C1q and tumor necrosis factor related protein 1
chr3_+_167453493 0.45 ENST00000295777.5
ENST00000472747.2
serpin peptidase inhibitor, clade I (neuroserpin), member 1
chr17_-_7080801 0.44 ENST00000572879.1
asialoglycoprotein receptor 1
chr17_+_77020325 0.44 ENST00000311661.4
C1q and tumor necrosis factor related protein 1
chr20_-_22565101 0.43 ENST00000419308.2
forkhead box A2
chr17_-_7081435 0.43 ENST00000380920.4
asialoglycoprotein receptor 1
chr19_+_41856816 0.43 ENST00000539627.1
transmembrane protein 91
chr8_-_145060593 0.43 ENST00000313059.5
ENST00000524918.1
ENST00000313028.7
ENST00000525773.1
poly (ADP-ribose) polymerase family, member 10
chr19_+_48867652 0.40 ENST00000344846.2
synaptogyrin 4
chr22_-_51017084 0.40 ENST00000360719.2
ENST00000457250.1
ENST00000440709.1
carnitine palmitoyltransferase 1B (muscle)
chr4_-_140222358 0.40 ENST00000505036.1
ENST00000544855.1
ENST00000539002.1
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr19_+_18723660 0.40 ENST00000262817.3
transmembrane protein 59-like
chr15_-_90294523 0.40 ENST00000300057.4
mesoderm posterior 1 homolog (mouse)
chr19_-_49622348 0.39 ENST00000408991.2
chromosome 19 open reading frame 73
chr19_+_1000418 0.39 ENST00000234389.3
glutamate receptor, ionotropic, N-methyl-D-aspartate 3B
chr12_+_57853918 0.39 ENST00000532291.1
ENST00000543426.1
ENST00000228682.2
ENST00000546141.1
GLI family zinc finger 1
chrX_-_49056635 0.38 ENST00000472598.1
ENST00000538567.1
ENST00000479808.1
ENST00000263233.4
synaptophysin
chr19_-_8579030 0.38 ENST00000255616.8
ENST00000393927.4
zinc finger protein 414
chr10_-_102279586 0.38 ENST00000370345.3
ENST00000451524.1
ENST00000370329.5
SEC31 homolog B (S. cerevisiae)
chrX_-_153775426 0.37 ENST00000393562.2
glucose-6-phosphate dehydrogenase
chr3_-_49459878 0.37 ENST00000546031.1
ENST00000458307.2
ENST00000430521.1
aminomethyltransferase
chr14_+_103573853 0.37 ENST00000560304.1
exocyst complex component 3-like 4
chr12_+_58148842 0.37 ENST00000266643.5
membrane-associated ring finger (C3HC4) 9
chr16_+_2820912 0.36 ENST00000570539.1
serine/arginine repetitive matrix 2
chr8_-_21988558 0.36 ENST00000312841.8
hair growth associated
chr16_+_57023406 0.36 ENST00000262510.6
ENST00000308149.7
ENST00000436936.1
NLR family, CARD domain containing 5
chr3_-_48632593 0.36 ENST00000454817.1
ENST00000328333.8
collagen, type VII, alpha 1
chr17_-_46703826 0.35 ENST00000550387.1
ENST00000311177.5
homeobox B9
chr4_+_102268904 0.34 ENST00000527564.1
ENST00000529296.1
Uncharacterized protein
chr5_-_176836577 0.33 ENST00000253496.3
coagulation factor XII (Hageman factor)
chr15_-_41099648 0.32 ENST00000220496.4
DnaJ (Hsp40) homolog, subfamily C, member 17
chr1_-_153518270 0.32 ENST00000354332.4
ENST00000368716.4
S100 calcium binding protein A4
chr1_-_25256368 0.32 ENST00000308873.6
runt-related transcription factor 3
chr19_+_50380917 0.32 ENST00000535102.2
TBC1 domain family, member 17
chr17_-_27229948 0.31 ENST00000426464.2
dehydrogenase/reductase (SDR family) member 13
chr19_-_10213335 0.31 ENST00000592641.1
ENST00000253109.4
angiopoietin-like 6
chr16_+_30662360 0.31 ENST00000542965.2
proline rich 14
chr19_-_11456905 0.31 ENST00000588560.1
ENST00000592952.1
transmembrane protein 205
chr19_-_11456872 0.31 ENST00000586218.1
transmembrane protein 205
chr3_-_49459865 0.31 ENST00000427987.1
aminomethyltransferase
chr4_-_176733897 0.31 ENST00000393658.2
glycoprotein M6A
chr17_+_77021702 0.30 ENST00000392445.2
ENST00000354124.3
C1q and tumor necrosis factor related protein 1
chr17_+_34430980 0.30 ENST00000250151.4
chemokine (C-C motif) ligand 4
chr5_-_100238956 0.30 ENST00000231461.5
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
chr2_+_171571827 0.30 ENST00000375281.3
Sp5 transcription factor
chr19_+_55795493 0.30 ENST00000309383.1
BR serine/threonine kinase 1
chr19_-_11456935 0.30 ENST00000590788.1
ENST00000586590.1
ENST00000589555.1
ENST00000586956.1
ENST00000593256.2
ENST00000447337.1
ENST00000591677.1
ENST00000586701.1
ENST00000589655.1
transmembrane protein 205
RAB3D, member RAS oncogene family
chr14_+_23938891 0.30 ENST00000408901.3
ENST00000397154.3
ENST00000555128.1
neuroguidin, EIF4E binding protein
chr14_-_24911868 0.29 ENST00000554698.1
short chain dehydrogenase/reductase family 39U, member 1
chr8_+_56014949 0.29 ENST00000327381.6
XK, Kell blood group complex subunit-related family, member 4
chr12_+_52203789 0.29 ENST00000599343.1
HCG1997999; cDNA FLJ33996 fis, clone DFNES2008881
chr1_+_153963227 0.28 ENST00000368567.4
ENST00000392558.4
ribosomal protein S27
chr19_-_42721819 0.28 ENST00000336034.4
ENST00000598200.1
ENST00000598727.1
ENST00000596251.1
death effector domain containing 2
chr8_+_87111059 0.28 ENST00000285393.3
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2
chr3_-_182880541 0.28 ENST00000470251.1
ENST00000265598.3
lysosomal-associated membrane protein 3
chr2_+_5832799 0.28 ENST00000322002.3
SRY (sex determining region Y)-box 11
chr7_+_100450328 0.27 ENST00000540482.1
ENST00000418037.1
ENST00000428758.1
ENST00000275729.3
ENST00000415287.1
ENST00000354161.3
ENST00000416675.1
solute carrier family 12, member 9
chr19_+_50380682 0.27 ENST00000221543.5
TBC1 domain family, member 17
chr1_-_151119087 0.27 ENST00000341697.3
ENST00000368914.3
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C
chr7_+_139528952 0.27 ENST00000416849.2
ENST00000436047.2
ENST00000414508.2
ENST00000448866.1
thromboxane A synthase 1 (platelet)
chr11_+_120081475 0.27 ENST00000328965.4
OAF homolog (Drosophila)
chr6_-_19804973 0.27 ENST00000457670.1
ENST00000607810.1
ENST00000606628.1
RP4-625H18.2
chr20_+_306221 0.27 ENST00000342665.2
SRY (sex determining region Y)-box 12
chr11_-_46142948 0.26 ENST00000257821.4
PHD finger protein 21A
chr17_+_77020146 0.26 ENST00000579760.1
C1q and tumor necrosis factor related protein 1
chr3_-_61237050 0.25 ENST00000476844.1
ENST00000488467.1
ENST00000492590.1
ENST00000468189.1
fragile histidine triad
chr16_-_67190152 0.25 ENST00000486556.1
TNFRSF1A-associated via death domain
chr10_-_131762105 0.25 ENST00000368648.3
ENST00000355311.5
early B-cell factor 3
chr22_-_36013368 0.25 ENST00000442617.1
ENST00000397326.2
ENST00000397328.1
ENST00000451685.1
myoglobin
chr17_-_15469590 0.25 ENST00000312127.2
CMT duplicated region transcript 1; Uncharacterized protein
chr13_-_79177673 0.25 ENST00000377208.5
POU class 4 homeobox 1
chr3_+_184080790 0.25 ENST00000430783.1
polymerase (RNA) II (DNA directed) polypeptide H
chr5_-_127418573 0.25 ENST00000508353.1
ENST00000508878.1
ENST00000501652.1
ENST00000514409.1
CTC-228N24.3
chr1_-_12677714 0.25 ENST00000376223.2
dehydrogenase/reductase (SDR family) member 3
chr17_-_27230035 0.25 ENST00000378895.4
ENST00000394901.3
dehydrogenase/reductase (SDR family) member 13
chr16_+_57844549 0.25 ENST00000564282.1
uncharacterized protein LOC388282
chr15_+_41099254 0.24 ENST00000570108.1
ENST00000564258.1
ENST00000355341.4
ENST00000336455.5
zinc finger, FYVE domain containing 19
chr4_+_166300084 0.24 ENST00000402744.4
carboxypeptidase E
chr9_-_96717654 0.24 ENST00000253968.6
BARX homeobox 1
chr18_+_3450161 0.24 ENST00000551402.1
ENST00000577543.1
TGFB-induced factor homeobox 1
chr16_+_30675654 0.24 ENST00000287468.5
ENST00000395073.2
fibrosin
chr5_-_127418755 0.24 ENST00000501702.2
ENST00000501173.2
ENST00000514573.1
ENST00000499346.2
ENST00000606251.1
CTC-228N24.3
chr8_-_123793048 0.23 ENST00000607710.1
RP11-44N11.2
chr19_-_10420459 0.23 ENST00000403352.1
ENST00000403903.3
zinc finger, GATA-like protein 1
chr2_+_43864387 0.23 ENST00000282406.4
pleckstrin homology domain containing, family H (with MyTH4 domain) member 2
chr14_-_24911971 0.23 ENST00000555365.1
ENST00000399395.3
short chain dehydrogenase/reductase family 39U, member 1
chr1_+_153746683 0.23 ENST00000271857.2
solute carrier family 27 (fatty acid transporter), member 3
chr22_-_39268308 0.23 ENST00000407418.3
chromobox homolog 6
chr19_-_47734448 0.23 ENST00000439096.2
BCL2 binding component 3
chr3_-_52719888 0.23 ENST00000458294.1
polybromo 1
chr17_+_37821593 0.22 ENST00000578283.1
titin-cap
chr12_+_57998595 0.22 ENST00000337737.3
ENST00000548198.1
ENST00000551632.1
deltex homolog 3 (Drosophila)
chr1_+_26737253 0.22 ENST00000326279.6
lin-28 homolog A (C. elegans)
chr11_-_67415048 0.22 ENST00000529256.1
aspartoacylase (aminocyclase) 3
chr16_+_777118 0.22 ENST00000562141.1
hydroxyacylglutathione hydrolase-like
chr6_+_122931366 0.22 ENST00000368452.2
ENST00000368448.1
ENST00000392490.1
protein kinase (cAMP-dependent, catalytic) inhibitor beta
chr2_+_172864490 0.22 ENST00000315796.4
methionyl aminopeptidase type 1D (mitochondrial)
chr20_+_306177 0.21 ENST00000544632.1
SRY (sex determining region Y)-box 12
chr19_+_10397648 0.21 ENST00000340992.4
ENST00000393717.2
intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
chr19_-_51875894 0.21 ENST00000600427.1
ENST00000595217.1
ENST00000221978.5
natural killer cell group 7 sequence
chr15_+_76030311 0.21 ENST00000543887.1
AC019294.1
chr5_-_134914673 0.21 ENST00000512158.1
chemokine (C-X-C motif) ligand 14
chr17_-_26220366 0.21 ENST00000460380.2
ENST00000508862.1
ENST00000379102.3
ENST00000582441.1
LYR motif containing 9
Uncharacterized protein
chr7_+_139529040 0.21 ENST00000455353.1
ENST00000458722.1
ENST00000411653.1
thromboxane A synthase 1 (platelet)
chr19_-_39108552 0.21 ENST00000591517.1
mitogen-activated protein kinase kinase kinase kinase 1
chrY_+_15016725 0.21 ENST00000336079.3
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
chr17_-_73937116 0.21 ENST00000586717.1
ENST00000389570.4
ENST00000319129.5
Fas (TNFRSF6) binding factor 1
chr12_-_121342170 0.21 ENST00000353487.2
signal peptide peptidase like 3
chr19_+_41107249 0.21 ENST00000396819.3
latent transforming growth factor beta binding protein 4
chr17_+_27055798 0.20 ENST00000268766.6
NIMA-related kinase 8
chr17_+_34431212 0.20 ENST00000394495.1
chemokine (C-C motif) ligand 4
chr13_+_46276441 0.20 ENST00000310521.1
ENST00000533564.1
spermatid associated
chr19_+_38794797 0.20 ENST00000301246.5
ENST00000588605.1
chromosome 19 open reading frame 33
chr1_+_228395755 0.20 ENST00000284548.11
ENST00000570156.2
ENST00000422127.1
ENST00000366707.4
ENST00000366709.4
obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
chr19_-_39421377 0.20 ENST00000430193.3
ENST00000600042.1
ENST00000221431.6
seryl-tRNA synthetase 2, mitochondrial
chr8_+_81397876 0.20 ENST00000430430.1
zinc finger and BTB domain containing 10
chr18_+_3449821 0.20 ENST00000407501.2
ENST00000405385.3
ENST00000546979.1
TGFB-induced factor homeobox 1
chr2_-_152589670 0.20 ENST00000604864.1
ENST00000603639.1
nebulin
chr19_-_3500635 0.20 ENST00000250937.3
deoxyhypusine hydroxylase/monooxygenase
chrX_-_34675391 0.20 ENST00000275954.3
transmembrane protein 47
chrX_-_80377162 0.19 ENST00000430960.1
ENST00000447319.1
high mobility group nucleosome binding domain 5
chr20_-_4055812 0.19 ENST00000379526.1
Uncharacterized protein
chr20_+_57875457 0.19 ENST00000337938.2
ENST00000311585.7
ENST00000371028.2
endothelin 3
chr20_+_48884002 0.19 ENST00000425497.1
ENST00000445003.1
RP11-290F20.3
chr3_-_178984759 0.19 ENST00000349697.2
ENST00000497599.1
potassium large conductance calcium-activated channel, subfamily M beta member 3
chrX_-_80377118 0.19 ENST00000373250.3
high mobility group nucleosome binding domain 5
chr22_+_38597889 0.19 ENST00000338483.2
ENST00000538320.1
ENST00000538999.1
ENST00000441709.1
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
chr19_-_39108643 0.19 ENST00000396857.2
mitogen-activated protein kinase kinase kinase kinase 1
chr22_-_30662828 0.19 ENST00000403463.1
ENST00000215781.2
oncostatin M
chr5_-_473135 0.19 ENST00000342584.3
Uncharacterized protein
chr7_-_74221288 0.18 ENST00000451013.2
GTF2I repeat domain containing 2
chr7_+_76139833 0.18 ENST00000257632.5
uroplakin 3B
chr2_+_11696464 0.18 ENST00000234142.5
growth regulation by estrogen in breast cancer 1
chr22_+_46481861 0.18 ENST00000360737.3
hsa-mir-4763
chr10_+_133918175 0.18 ENST00000298622.4
Janus kinase and microtubule interacting protein 3
chr1_+_168250194 0.18 ENST00000367821.3
T-box 19
chr22_-_38539185 0.18 ENST00000452542.1
phospholipase A2, group VI (cytosolic, calcium-independent)
chr18_+_3449695 0.18 ENST00000343820.5
TGFB-induced factor homeobox 1
chr20_-_52645231 0.17 ENST00000448484.1
breast carcinoma amplified sequence 1
chrX_+_153672468 0.17 ENST00000393600.3
family with sequence similarity 50, member A
chr4_-_120133661 0.17 ENST00000503243.1
ENST00000326780.3
Uncharacterized protein
chr2_+_204192942 0.17 ENST00000295851.5
ENST00000261017.5
abl-interactor 2
chr17_-_39156138 0.17 ENST00000391587.1
keratin associated protein 3-2
chr17_-_72968837 0.17 ENST00000581676.1
HID1 domain containing
chr11_-_45939565 0.17 ENST00000525192.1
ENST00000378750.5
peroxisomal biogenesis factor 16
chr6_-_19804877 0.17 ENST00000447250.1
RP4-625H18.2
chr19_-_48867291 0.17 ENST00000435956.3
transmembrane protein 143
chr19_+_38755042 0.17 ENST00000301244.7
serine peptidase inhibitor, Kunitz type, 2
chr12_+_7055767 0.17 ENST00000447931.2
protein tyrosine phosphatase, non-receptor type 6
chr9_-_98784042 0.17 ENST00000412122.2
long intergenic non-protein coding RNA 92
chr8_-_144655141 0.16 ENST00000398882.3
maestro heat-like repeat family member 6
chr4_-_69111401 0.16 ENST00000332644.5
transmembrane protease, serine 11B
chr10_+_135340859 0.16 ENST00000252945.3
ENST00000421586.1
ENST00000418356.1
cytochrome P450, family 2, subfamily E, polypeptide 1
chr17_+_53342311 0.16 ENST00000226067.5
hepatic leukemia factor
chr10_+_7860460 0.16 ENST00000344293.5
TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa
chr11_-_57479673 0.16 ENST00000337672.2
ENST00000431606.2
mediator complex subunit 19
chr4_-_73434498 0.16 ENST00000286657.4
ADAM metallopeptidase with thrombospondin type 1 motif, 3
chr19_-_46526304 0.16 ENST00000008938.4
peptidoglycan recognition protein 1
chr1_+_185703513 0.16 ENST00000271588.4
ENST00000367492.2
hemicentin 1
chr2_-_200322723 0.16 ENST00000417098.1
SATB homeobox 2
chr12_+_56661033 0.16 ENST00000433805.2
coenzyme Q10 homolog A (S. cerevisiae)
chr9_-_35815013 0.16 ENST00000259667.5
histidine triad nucleotide binding protein 2
chr13_-_36429763 0.15 ENST00000379893.1
doublecortin-like kinase 1
chr19_+_38755203 0.15 ENST00000587090.1
ENST00000454580.3
serine peptidase inhibitor, Kunitz type, 2
chr12_+_57998400 0.15 ENST00000548804.1
ENST00000550596.1
ENST00000551835.1
ENST00000549583.1
deltex homolog 3 (Drosophila)
chr17_-_74533963 0.15 ENST00000293230.5
cytoglobin
chr3_-_9811595 0.15 ENST00000256460.3
calcium/calmodulin-dependent protein kinase I
chr17_+_68164752 0.15 ENST00000535240.1
potassium inwardly-rectifying channel, subfamily J, member 2
chr3_+_42947600 0.15 ENST00000328199.6
ENST00000541208.1
zinc finger protein 662
chr3_+_52719936 0.15 ENST00000418458.1
ENST00000394799.2
guanine nucleotide binding protein-like 3 (nucleolar)
chr22_+_38201114 0.15 ENST00000340857.2
H1 histone family, member 0
chr11_-_45939374 0.15 ENST00000533151.1
ENST00000241041.3
peroxisomal biogenesis factor 16
chr9_+_96717821 0.15 ENST00000454594.1
RP11-231K24.2
chr6_+_43445261 0.15 ENST00000372444.2
ENST00000372445.5
ENST00000436109.2
ENST00000372454.2
ENST00000442878.2
ENST00000259751.1
ENST00000372452.1
ENST00000372449.1
tight junction associated protein 1 (peripheral)
chr1_+_47901689 0.15 ENST00000334793.5
forkhead box D2
chr19_+_10397621 0.15 ENST00000380770.3
intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
chr13_-_34250861 0.14 ENST00000445227.1
ENST00000454681.2
RP11-141M1.3
chr11_-_17555421 0.14 ENST00000526181.1
Usher syndrome 1C (autosomal recessive, severe)
chrX_+_129473916 0.14 ENST00000545805.1
ENST00000543953.1
ENST00000218197.5
solute carrier family 25 (mitochondrial carrier, brain), member 14
chr6_+_25652432 0.14 ENST00000377961.2
secretagogin, EF-hand calcium binding protein
chr17_-_46507567 0.14 ENST00000584924.1
src kinase associated phosphoprotein 1

Network of associatons between targets according to the STRING database.

First level regulatory network of TBX5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.8 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.3 3.0 GO:0001661 conditioned taste aversion(GO:0001661)
0.2 1.5 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.2 0.8 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.1 0.7 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.1 0.4 GO:0100012 regulation of heart induction(GO:0090381) regulation of heart induction by canonical Wnt signaling pathway(GO:0100012) negative regulation of endodermal cell differentiation(GO:1903225)
0.1 0.5 GO:0060032 notochord regression(GO:0060032)
0.1 0.3 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541) positive regulation of fibrinolysis(GO:0051919)
0.1 0.5 GO:0032425 positive regulation of mismatch repair(GO:0032425)
0.1 0.4 GO:0045013 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.1 0.3 GO:0032581 ER-dependent peroxisome organization(GO:0032581)
0.1 0.7 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.1 1.0 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.1 0.3 GO:0061386 closure of optic fissure(GO:0061386)
0.1 0.5 GO:0061624 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.1 0.4 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.1 0.2 GO:0030070 insulin processing(GO:0030070)
0.1 0.8 GO:0045345 positive regulation of MHC class I biosynthetic process(GO:0045345)
0.1 1.9 GO:0006853 carnitine shuttle(GO:0006853)
0.1 0.2 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
0.1 0.2 GO:1900073 regulation of neuromuscular synaptic transmission(GO:1900073) positive regulation of neuromuscular synaptic transmission(GO:1900075)
0.1 0.3 GO:0021538 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.1 0.4 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.1 0.3 GO:0014826 vein smooth muscle contraction(GO:0014826)
0.1 0.2 GO:2000854 positive regulation of corticosterone secretion(GO:2000854)
0.1 0.3 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.1 0.4 GO:0060671 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.1 0.2 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.1 0.2 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.1 0.2 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.1 0.2 GO:0032824 negative regulation of natural killer cell differentiation(GO:0032824) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827) positive regulation of cytolysis in other organism(GO:0051714)
0.1 0.1 GO:0014724 regulation of twitch skeletal muscle contraction(GO:0014724)
0.0 0.5 GO:0045591 positive regulation of regulatory T cell differentiation(GO:0045591)
0.0 0.3 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.0 0.1 GO:0030185 nitric oxide transport(GO:0030185)
0.0 0.1 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) negative regulation of neuromuscular junction development(GO:1904397)
0.0 0.2 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.1 GO:0045720 negative regulation of integrin biosynthetic process(GO:0045720)
0.0 0.1 GO:0071288 cellular response to mercury ion(GO:0071288)
0.0 0.1 GO:1904106 protein localization to microvillus(GO:1904106)
0.0 0.2 GO:0044878 mitotic cytokinesis checkpoint(GO:0044878)
0.0 0.0 GO:2000196 positive regulation of female gonad development(GO:2000196)
0.0 0.2 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.0 0.2 GO:0036309 protein localization to M-band(GO:0036309)
0.0 0.2 GO:0010193 response to ozone(GO:0010193)
0.0 0.3 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.1 GO:0031247 actin rod assembly(GO:0031247)
0.0 0.4 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.0 0.3 GO:0043353 slow-twitch skeletal muscle fiber contraction(GO:0031444) enucleate erythrocyte differentiation(GO:0043353)
0.0 0.2 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 0.7 GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030949)
0.0 0.2 GO:2000490 negative regulation of hepatic stellate cell activation(GO:2000490)
0.0 0.1 GO:0006427 histidyl-tRNA aminoacylation(GO:0006427)
0.0 0.5 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.0 0.1 GO:0003245 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.0 0.2 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0 0.1 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.0 0.1 GO:1903719 regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
0.0 0.2 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.1 GO:0099551 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551)
0.0 0.5 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.1 GO:0010728 positive regulation of hydrogen peroxide metabolic process(GO:0010726) regulation of hydrogen peroxide biosynthetic process(GO:0010728)
0.0 0.1 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.0 0.1 GO:0035803 egg coat formation(GO:0035803)
0.0 0.1 GO:0019050 suppression by virus of host apoptotic process(GO:0019050) modulation by virus of host apoptotic process(GO:0039526)
0.0 0.1 GO:0007343 egg activation(GO:0007343)
0.0 0.1 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.0 0.4 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.2 GO:0090238 positive regulation of arachidonic acid secretion(GO:0090238)
0.0 0.2 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.0 0.1 GO:0042938 dipeptide transport(GO:0042938)
0.0 0.4 GO:0051601 exocyst localization(GO:0051601)
0.0 0.1 GO:0001712 ectodermal cell fate commitment(GO:0001712)
0.0 0.2 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.0 0.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.1 GO:0070346 positive regulation of fat cell proliferation(GO:0070346)
0.0 0.3 GO:0071550 death-inducing signaling complex assembly(GO:0071550)
0.0 0.5 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.3 GO:0007035 vacuolar acidification(GO:0007035)
0.0 0.1 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.0 0.1 GO:0019348 dolichol metabolic process(GO:0019348)
0.0 0.1 GO:0003138 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.0 0.0 GO:1902362 melanocyte apoptotic process(GO:1902362)
0.0 0.1 GO:0042377 menaquinone catabolic process(GO:0042361) vitamin K catabolic process(GO:0042377)
0.0 0.3 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.3 GO:0016075 rRNA catabolic process(GO:0016075)
0.0 0.1 GO:0072308 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308)
0.0 0.2 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 0.1 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.0 0.4 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.1 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.0 0.1 GO:0035494 SNARE complex disassembly(GO:0035494)
0.0 0.2 GO:0035330 regulation of hippo signaling(GO:0035330)
0.0 0.3 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.1 GO:0086018 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373) SA node cell action potential(GO:0086015) SA node cell to atrial cardiac muscle cell signalling(GO:0086018)
0.0 0.1 GO:0035799 ureter maturation(GO:0035799)
0.0 0.2 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
0.0 0.1 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.0 0.0 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.0 0.1 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.1 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.0 0.2 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.3 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.0 0.3 GO:0051480 regulation of cytosolic calcium ion concentration(GO:0051480)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.0 GO:0035976 AP1 complex(GO:0035976)
0.2 0.7 GO:0071062 rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.2 0.5 GO:0032002 interleukin-28 receptor complex(GO:0032002)
0.1 0.4 GO:0030934 anchoring collagen complex(GO:0030934)
0.1 0.2 GO:0097543 ciliary inversin compartment(GO:0097543)
0.0 0.2 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.0 0.2 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.2 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.0 0.3 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 2.2 GO:0015030 Cajal body(GO:0015030)
0.0 0.1 GO:0032279 asymmetric synapse(GO:0032279) symmetric synapse(GO:0032280)
0.0 0.2 GO:0097013 phagocytic vesicle lumen(GO:0097013)
0.0 0.1 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.1 GO:0020005 symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005)
0.0 0.2 GO:0061200 clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0 0.2 GO:0031209 SCAR complex(GO:0031209)
0.0 0.4 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.4 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.4 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.1 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.1 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.1 GO:1903439 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.0 0.2 GO:0099634 postsynaptic specialization membrane(GO:0099634)
0.0 1.6 GO:0005581 collagen trimer(GO:0005581)
0.0 0.1 GO:0042025 host cell nucleus(GO:0042025)
0.0 0.8 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.2 GO:0042622 photoreceptor outer segment membrane(GO:0042622)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0008859 exoribonuclease II activity(GO:0008859)
0.2 1.8 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.2 0.7 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.1 0.5 GO:0004796 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.1 0.5 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
0.1 0.5 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.1 0.9 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.1 0.4 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.1 0.2 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.1 0.3 GO:0031708 endothelin B receptor binding(GO:0031708)
0.1 0.5 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.1 0.2 GO:0047888 fatty acid peroxidase activity(GO:0047888)
0.0 0.4 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.3 GO:0034711 inhibin binding(GO:0034711)
0.0 3.0 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.2 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.0 0.1 GO:0015633 zinc transporting ATPase activity(GO:0015633)
0.0 0.1 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.0 0.2 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 0.7 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.0 0.2 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.1 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.0 0.1 GO:0004821 histidine-tRNA ligase activity(GO:0004821)
0.0 0.2 GO:0051373 FATZ binding(GO:0051373)
0.0 0.1 GO:0001632 leukotriene B4 receptor activity(GO:0001632)
0.0 0.2 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.0 0.6 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.3 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.1 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.0 0.7 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.2 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.1 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.0 0.1 GO:0038131 neuregulin receptor activity(GO:0038131)
0.0 0.4 GO:0070513 death domain binding(GO:0070513)
0.0 0.2 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.1 GO:0003881 CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity(GO:0003881)
0.0 0.3 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.5 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.4 GO:0016594 glycine binding(GO:0016594)
0.0 0.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.1 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.0 0.1 GO:0004948 calcitonin receptor activity(GO:0004948)
0.0 0.1 GO:0005427 proton-dependent oligopeptide secondary active transmembrane transporter activity(GO:0005427) secondary active oligopeptide transmembrane transporter activity(GO:0015322)
0.0 0.1 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.1 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.0 0.2 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.3 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.0 0.4 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.1 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.0 0.2 GO:0048039 ubiquinone binding(GO:0048039)
0.0 0.1 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.0 0.1 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 0.2 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.0 0.3 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.2 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 0.4 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.1 GO:0032190 acrosin binding(GO:0032190)
0.0 0.1 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0 0.1 GO:0046790 virion binding(GO:0046790)
0.0 0.3 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.0 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.0 0.2 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.8 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.2 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.2 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 1.0 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.1 GO:0004028 retinal dehydrogenase activity(GO:0001758) 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0 0.1 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.0 0.1 GO:0046625 sphingolipid binding(GO:0046625)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.0 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.5 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 1.6 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.6 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.4 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.2 PID RAC1 PATHWAY RAC1 signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.0 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 1.9 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.8 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.5 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 1.8 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.8 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.3 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.6 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.4 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.1 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.7 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.1 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels