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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for TCF21

Z-value: 0.66

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Transcription factors associated with TCF21

Gene Symbol Gene ID Gene Info
TCF21
ENSG00000118526.6 transcription factor 21

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TCF21hg19_v2_chr6_+_134210243_1342102760.596.6e-03Click!

Activity profile of TCF21 motif

Sorted Z-values of TCF21 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr20_-_52790055 1.82 ENST00000395955.3
CYP24A1
cytochrome P450, family 24, subfamily A, polypeptide 1
chr17_-_15165854 1.55 ENST00000395936.1
ENST00000395938.2
PMP22
peripheral myelin protein 22
chr2_-_225811747 1.47 ENST00000409592.3
DOCK10
dedicator of cytokinesis 10
chr9_-_123812542 1.40 ENST00000223642.1
C5
complement component 5
chrX_+_69509927 1.39 ENST00000374403.3
KIF4A
kinesin family member 4A
chr2_-_234763105 1.35 ENST00000454020.1
HJURP
Holliday junction recognition protein
chr2_-_25100893 1.34 ENST00000433852.1
ADCY3
adenylate cyclase 3
chr9_+_118950325 1.31 ENST00000534838.1
PAPPA
pregnancy-associated plasma protein A, pappalysin 1
chr17_+_6347761 1.24 ENST00000250056.8
ENST00000571373.1
ENST00000570337.2
ENST00000572595.2
ENST00000576056.1
FAM64A
family with sequence similarity 64, member A
chr7_-_47578840 1.20 ENST00000450444.1
TNS3
tensin 3
chr8_-_19540266 1.19 ENST00000311540.4
CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr8_-_19540086 1.16 ENST00000332246.6
CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr14_-_23288930 1.07 ENST00000554517.1
ENST00000285850.7
ENST00000397529.2
ENST00000555702.1
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr17_-_15165825 1.07 ENST00000426385.3
PMP22
peripheral myelin protein 22
chr4_-_89152474 1.04 ENST00000515655.1
ABCG2
ATP-binding cassette, sub-family G (WHITE), member 2
chr5_+_68462837 1.00 ENST00000256442.5
CCNB1
cyclin B1
chr5_+_68462944 1.00 ENST00000506572.1
CCNB1
cyclin B1
chr5_+_68463043 0.98 ENST00000508407.1
ENST00000505500.1
CCNB1
cyclin B1
chr17_+_6347729 0.97 ENST00000572447.1
FAM64A
family with sequence similarity 64, member A
chr5_-_58571935 0.96 ENST00000503258.1
PDE4D
phosphodiesterase 4D, cAMP-specific
chr15_+_89787180 0.92 ENST00000300027.8
ENST00000310775.7
ENST00000567891.1
ENST00000564920.1
ENST00000565255.1
ENST00000567996.1
ENST00000451393.2
ENST00000563250.1
FANCI
Fanconi anemia, complementation group I
chr5_-_142784003 0.91 ENST00000416954.2
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr11_+_123430948 0.89 ENST00000529432.1
ENST00000534764.1
GRAMD1B
GRAM domain containing 1B
chr2_+_38177575 0.87 ENST00000407257.1
ENST00000417700.2
ENST00000234195.3
ENST00000442857.1
RMDN2
regulator of microtubule dynamics 2
chr17_-_43025005 0.87 ENST00000587309.1
ENST00000593135.1
ENST00000339151.4
KIF18B
kinesin family member 18B
chr11_-_10920838 0.86 ENST00000503469.2
CTD-2003C8.2
CTD-2003C8.2
chr12_-_52585765 0.86 ENST00000313234.5
ENST00000394815.2
KRT80
keratin 80
chr17_+_71229346 0.84 ENST00000535032.2
ENST00000582793.1
C17orf80
chromosome 17 open reading frame 80
chr2_-_234763147 0.82 ENST00000411486.2
ENST00000432087.1
ENST00000441687.1
ENST00000414924.1
HJURP
Holliday junction recognition protein
chr12_-_6960407 0.81 ENST00000540683.1
ENST00000229265.6
ENST00000535406.1
ENST00000422785.3
CDCA3
cell division cycle associated 3
chr2_-_42160486 0.77 ENST00000427054.1
AC104654.2
AC104654.2
chr19_-_4559814 0.77 ENST00000586582.1
SEMA6B
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
chr12_-_105352047 0.76 ENST00000432951.1
ENST00000415674.1
ENST00000424946.1
SLC41A2
solute carrier family 41 (magnesium transporter), member 2
chr8_-_71519889 0.73 ENST00000521425.1
TRAM1
translocation associated membrane protein 1
chr10_+_94594351 0.73 ENST00000371552.4
EXOC6
exocyst complex component 6
chr22_-_22863466 0.72 ENST00000406426.1
ENST00000360412.2
ZNF280B
zinc finger protein 280B
chr7_-_11871815 0.71 ENST00000423059.4
THSD7A
thrombospondin, type I, domain containing 7A
chr4_-_89442940 0.71 ENST00000527353.1
PIGY
phosphatidylinositol glycan anchor biosynthesis, class Y
chr1_-_94374946 0.68 ENST00000370238.3
GCLM
glutamate-cysteine ligase, modifier subunit
chr15_+_65843130 0.68 ENST00000569894.1
PTPLAD1
protein tyrosine phosphatase-like A domain containing 1
chr11_-_31531121 0.68 ENST00000532287.1
ENST00000526776.1
ENST00000534812.1
ENST00000529749.1
ENST00000278200.1
ENST00000530023.1
ENST00000533642.1
IMMP1L
IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr11_+_7597639 0.66 ENST00000533792.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr5_+_10564432 0.66 ENST00000296657.5
ANKRD33B
ankyrin repeat domain 33B
chr13_+_51483814 0.65 ENST00000336617.3
ENST00000422660.1
RNASEH2B
ribonuclease H2, subunit B
chr20_+_34802295 0.65 ENST00000432603.1
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr11_+_74862032 0.65 ENST00000289575.5
ENST00000341411.4
SLCO2B1
solute carrier organic anion transporter family, member 2B1
chr3_+_101498074 0.64 ENST00000273347.5
ENST00000474165.1
NXPE3
neurexophilin and PC-esterase domain family, member 3
chr11_+_72975524 0.64 ENST00000540342.1
ENST00000542092.1
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr5_+_139055021 0.63 ENST00000502716.1
ENST00000503511.1
CXXC5
CXXC finger protein 5
chr14_-_50154921 0.63 ENST00000553805.2
ENST00000554396.1
ENST00000216367.5
ENST00000539565.2
POLE2
polymerase (DNA directed), epsilon 2, accessory subunit
chr15_+_57998923 0.62 ENST00000380557.4
POLR2M
polymerase (RNA) II (DNA directed) polypeptide M
chr12_-_58329819 0.62 ENST00000551421.1
RP11-620J15.3
RP11-620J15.3
chr5_+_139055055 0.62 ENST00000511457.1
CXXC5
CXXC finger protein 5
chr10_+_35415719 0.60 ENST00000474362.1
ENST00000374721.3
CREM
cAMP responsive element modulator
chr2_-_228028829 0.60 ENST00000396625.3
ENST00000329662.7
COL4A4
collagen, type IV, alpha 4
chr2_+_101437487 0.60 ENST00000427413.1
ENST00000542504.1
NPAS2
neuronal PAS domain protein 2
chr20_+_30327063 0.60 ENST00000300403.6
ENST00000340513.4
TPX2
TPX2, microtubule-associated
chr11_+_125496619 0.60 ENST00000532669.1
ENST00000278916.3
CHEK1
checkpoint kinase 1
chr15_+_63354769 0.59 ENST00000558910.1
TPM1
tropomyosin 1 (alpha)
chr16_-_46655538 0.59 ENST00000303383.3
SHCBP1
SHC SH2-domain binding protein 1
chr16_-_4323015 0.58 ENST00000204517.6
TFAP4
transcription factor AP-4 (activating enhancer binding protein 4)
chr17_-_63052929 0.58 ENST00000439174.2
GNA13
guanine nucleotide binding protein (G protein), alpha 13
chr6_-_74161977 0.58 ENST00000370318.1
ENST00000370315.3
MB21D1
Mab-21 domain containing 1
chr11_+_31531291 0.57 ENST00000350638.5
ENST00000379163.5
ENST00000395934.2
ELP4
elongator acetyltransferase complex subunit 4
chr4_-_123844084 0.57 ENST00000339154.2
NUDT6
nudix (nucleoside diphosphate linked moiety X)-type motif 6
chr8_+_38585704 0.57 ENST00000519416.1
ENST00000520615.1
TACC1
transforming, acidic coiled-coil containing protein 1
chr11_+_74862140 0.56 ENST00000525650.1
ENST00000454962.2
SLCO2B1
solute carrier organic anion transporter family, member 2B1
chr16_-_31076332 0.56 ENST00000539836.3
ENST00000535577.1
ENST00000442862.2
ZNF668
zinc finger protein 668
chr22_+_44427230 0.56 ENST00000444029.1
PARVB
parvin, beta
chr6_-_27835357 0.56 ENST00000331442.3
HIST1H1B
histone cluster 1, H1b
chr17_-_46671323 0.56 ENST00000239151.5
HOXB5
homeobox B5
chr3_-_49058479 0.55 ENST00000440857.1
DALRD3
DALR anticodon binding domain containing 3
chrX_-_107334790 0.55 ENST00000217958.3
PSMD10
proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
chr11_+_74862100 0.55 ENST00000532236.1
ENST00000531756.1
SLCO2B1
solute carrier organic anion transporter family, member 2B1
chr1_-_226595648 0.55 ENST00000366790.3
PARP1
poly (ADP-ribose) polymerase 1
chrX_-_150067069 0.54 ENST00000466436.1
CD99L2
CD99 molecule-like 2
chr15_+_57998821 0.54 ENST00000299638.3
POLR2M
polymerase (RNA) II (DNA directed) polypeptide M
chr19_-_41903161 0.54 ENST00000602129.1
ENST00000593771.1
ENST00000596905.1
ENST00000221233.4
EXOSC5
exosome component 5
chr10_+_60094735 0.54 ENST00000373910.4
UBE2D1
ubiquitin-conjugating enzyme E2D 1
chr17_+_16593539 0.54 ENST00000340621.5
ENST00000399273.1
ENST00000443444.2
ENST00000360524.8
ENST00000456009.1
CCDC144A
coiled-coil domain containing 144A
chr8_-_92053212 0.54 ENST00000285419.3
TMEM55A
transmembrane protein 55A
chr5_+_170288856 0.53 ENST00000523189.1
RANBP17
RAN binding protein 17
chr1_-_8000872 0.53 ENST00000377507.3
TNFRSF9
tumor necrosis factor receptor superfamily, member 9
chr2_-_191115229 0.52 ENST00000409820.2
ENST00000410045.1
HIBCH
3-hydroxyisobutyryl-CoA hydrolase
chr15_-_83240507 0.52 ENST00000564522.1
ENST00000398592.2
CPEB1
cytoplasmic polyadenylation element binding protein 1
chr4_-_123843597 0.52 ENST00000510735.1
ENST00000304430.5
NUDT6
nudix (nucleoside diphosphate linked moiety X)-type motif 6
chr14_-_53258180 0.52 ENST00000554230.1
GNPNAT1
glucosamine-phosphate N-acetyltransferase 1
chr5_+_71475449 0.50 ENST00000504492.1
MAP1B
microtubule-associated protein 1B
chr5_-_59995921 0.50 ENST00000453022.2
ENST00000545085.1
ENST00000265036.5
DEPDC1B
DEP domain containing 1B
chr9_-_123239632 0.50 ENST00000416449.1
CDK5RAP2
CDK5 regulatory subunit associated protein 2
chr11_+_72975578 0.50 ENST00000393592.2
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr17_+_71228740 0.50 ENST00000268942.8
ENST00000359042.2
C17orf80
chromosome 17 open reading frame 80
chr17_-_191188 0.49 ENST00000575634.1
RPH3AL
rabphilin 3A-like (without C2 domains)
chr2_+_63816126 0.49 ENST00000454035.1
MDH1
malate dehydrogenase 1, NAD (soluble)
chr11_-_115127611 0.49 ENST00000545094.1
CADM1
cell adhesion molecule 1
chr11_+_72975559 0.48 ENST00000349767.2
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr12_-_68845417 0.48 ENST00000542875.1
RP11-81H14.2
RP11-81H14.2
chr17_+_34848049 0.47 ENST00000588902.1
ENST00000591067.1
ZNHIT3
zinc finger, HIT-type containing 3
chr2_-_55276320 0.47 ENST00000357376.3
RTN4
reticulon 4
chr5_-_142784101 0.46 ENST00000503201.1
ENST00000502892.1
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chrX_-_107334750 0.45 ENST00000340200.5
ENST00000372296.1
ENST00000372295.1
ENST00000361815.5
PSMD10
proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
chr21_+_30673091 0.45 ENST00000447177.1
BACH1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr7_+_87563557 0.45 ENST00000439864.1
ENST00000412441.1
ENST00000398201.4
ENST00000265727.7
ENST00000315984.7
ENST00000398209.3
ADAM22
ADAM metallopeptidase domain 22
chr7_-_99698338 0.44 ENST00000354230.3
ENST00000425308.1
MCM7
minichromosome maintenance complex component 7
chr12_+_78224667 0.44 ENST00000549464.1
NAV3
neuron navigator 3
chr3_-_81792780 0.43 ENST00000489715.1
GBE1
glucan (1,4-alpha-), branching enzyme 1
chrX_+_9431324 0.43 ENST00000407597.2
ENST00000424279.1
ENST00000536365.1
ENST00000441088.1
ENST00000380961.1
ENST00000415293.1
TBL1X
transducin (beta)-like 1X-linked
chr2_-_122494487 0.42 ENST00000451734.1
ENST00000285814.4
MKI67IP
nucleolar protein interacting with the FHA domain of MKI67
chr16_-_5147743 0.42 ENST00000587133.1
ENST00000458008.4
ENST00000427587.4
FAM86A
family with sequence similarity 86, member A
chr11_+_32112431 0.41 ENST00000054950.3
RCN1
reticulocalbin 1, EF-hand calcium binding domain
chr2_-_17981462 0.41 ENST00000402989.1
ENST00000428868.1
SMC6
structural maintenance of chromosomes 6
chr17_+_39421591 0.41 ENST00000391355.1
KRTAP9-6
keratin associated protein 9-6
chr15_+_63796779 0.40 ENST00000561442.1
ENST00000560070.1
ENST00000540797.1
ENST00000380324.3
ENST00000268049.7
ENST00000536001.1
ENST00000539772.1
USP3
ubiquitin specific peptidase 3
chr17_+_71228793 0.40 ENST00000426147.2
C17orf80
chromosome 17 open reading frame 80
chr21_+_30672433 0.40 ENST00000451655.1
BACH1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr19_+_35485682 0.40 ENST00000599564.1
GRAMD1A
GRAM domain containing 1A
chr4_+_95972822 0.40 ENST00000509540.1
ENST00000440890.2
BMPR1B
bone morphogenetic protein receptor, type IB
chr17_-_19265855 0.40 ENST00000440841.1
ENST00000395615.1
ENST00000461069.2
B9D1
B9 protein domain 1
chr3_+_101498269 0.39 ENST00000491511.2
NXPE3
neurexophilin and PC-esterase domain family, member 3
chr1_-_23857698 0.39 ENST00000361729.2
E2F2
E2F transcription factor 2
chr11_+_71498552 0.39 ENST00000346333.6
ENST00000359244.4
ENST00000426628.2
FAM86C1
family with sequence similarity 86, member C1
chr20_-_54967187 0.38 ENST00000422322.1
ENST00000371356.2
ENST00000451915.1
ENST00000347343.2
ENST00000395911.1
ENST00000395907.1
ENST00000441357.1
ENST00000456249.1
ENST00000420474.1
ENST00000395909.4
ENST00000395914.1
ENST00000312783.6
ENST00000395915.3
ENST00000395913.3
AURKA
aurora kinase A
chr2_+_63816295 0.38 ENST00000539945.1
ENST00000544381.1
MDH1
malate dehydrogenase 1, NAD (soluble)
chr10_+_35415978 0.38 ENST00000429130.3
ENST00000469949.2
ENST00000460270.1
CREM
cAMP responsive element modulator
chr19_+_50191921 0.38 ENST00000420022.3
ADM5
adrenomedullin 5 (putative)
chr22_+_40742512 0.37 ENST00000454266.2
ENST00000342312.6
ADSL
adenylosuccinate lyase
chr3_+_113666748 0.37 ENST00000330212.3
ENST00000498275.1
ZDHHC23
zinc finger, DHHC-type containing 23
chr1_-_114429997 0.37 ENST00000471267.1
ENST00000393320.3
BCL2L15
BCL2-like 15
chr2_+_63816269 0.37 ENST00000432309.1
MDH1
malate dehydrogenase 1, NAD (soluble)
chr11_-_14913765 0.36 ENST00000334636.5
CYP2R1
cytochrome P450, family 2, subfamily R, polypeptide 1
chrX_+_17755563 0.36 ENST00000380045.3
ENST00000380041.3
ENST00000380043.3
ENST00000398080.1
SCML1
sex comb on midleg-like 1 (Drosophila)
chr2_-_3595547 0.36 ENST00000438485.1
RP13-512J5.1
Uncharacterized protein
chr2_+_63816087 0.36 ENST00000409908.1
ENST00000442225.1
ENST00000409476.1
ENST00000436321.1
MDH1
malate dehydrogenase 1, NAD (soluble)
chr8_-_117886955 0.35 ENST00000297338.2
RAD21
RAD21 homolog (S. pombe)
chr11_+_125496400 0.34 ENST00000524737.1
CHEK1
checkpoint kinase 1
chr16_+_85936295 0.34 ENST00000563180.1
ENST00000564617.1
ENST00000564803.1
IRF8
interferon regulatory factor 8
chr16_+_83932684 0.34 ENST00000262430.4
MLYCD
malonyl-CoA decarboxylase
chr17_-_42466864 0.34 ENST00000353281.4
ENST00000262407.5
ITGA2B
integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
chr15_+_75487984 0.34 ENST00000563905.1
C15orf39
chromosome 15 open reading frame 39
chr1_-_243326612 0.34 ENST00000492145.1
ENST00000490813.1
ENST00000464936.1
CEP170
centrosomal protein 170kDa
chr11_+_125496124 0.34 ENST00000533778.2
ENST00000534070.1
CHEK1
checkpoint kinase 1
chr17_-_62499334 0.34 ENST00000579996.1
DDX5
DEAD (Asp-Glu-Ala-Asp) box helicase 5
chr10_-_46641003 0.33 ENST00000395721.2
ENST00000374218.2
ENST00000395725.3
ENST00000374346.3
ENST00000417004.1
PTPN20A
protein tyrosine phosphatase, non-receptor type 20A
chr11_-_62457371 0.33 ENST00000317449.4
LRRN4CL
LRRN4 C-terminal like
chr2_+_102721023 0.33 ENST00000409589.1
ENST00000409329.1
IL1R1
interleukin 1 receptor, type I
chr19_-_4867643 0.33 ENST00000589034.1
PLIN3
perilipin 3
chr11_-_14913190 0.33 ENST00000532378.1
CYP2R1
cytochrome P450, family 2, subfamily R, polypeptide 1
chr19_-_17186229 0.32 ENST00000253669.5
ENST00000448593.2
HAUS8
HAUS augmin-like complex, subunit 8
chr1_+_46049706 0.32 ENST00000527470.1
ENST00000525515.1
ENST00000537798.1
ENST00000402363.3
ENST00000528238.1
ENST00000350030.3
ENST00000470768.1
ENST00000372052.4
ENST00000351223.3
NASP
nuclear autoantigenic sperm protein (histone-binding)
chr16_-_70323422 0.32 ENST00000261772.8
AARS
alanyl-tRNA synthetase
chrX_-_16887963 0.31 ENST00000380084.4
RBBP7
retinoblastoma binding protein 7
chr2_+_33701684 0.31 ENST00000442390.1
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr3_-_5229982 0.31 ENST00000600805.1
AC026202.1
Uncharacterized protein
chr17_+_29421987 0.31 ENST00000431387.4
NF1
neurofibromin 1
chr3_+_141106643 0.31 ENST00000514251.1
ZBTB38
zinc finger and BTB domain containing 38
chr3_+_49058444 0.30 ENST00000326925.6
ENST00000395458.2
NDUFAF3
NADH dehydrogenase (ubiquinone) complex I, assembly factor 3
chr14_+_104710541 0.30 ENST00000419115.1
C14orf144
chromosome 14 open reading frame 144
chr4_+_37892682 0.30 ENST00000508802.1
ENST00000261439.4
ENST00000402522.1
TBC1D1
TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
chr5_+_130506629 0.30 ENST00000510516.1
ENST00000507584.1
LYRM7
LYR motif containing 7
chr6_-_30658745 0.30 ENST00000376420.5
ENST00000376421.5
NRM
nurim (nuclear envelope membrane protein)
chr8_+_9413410 0.30 ENST00000520408.1
ENST00000310430.6
ENST00000522110.1
TNKS
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr1_-_161993422 0.30 ENST00000367940.2
OLFML2B
olfactomedin-like 2B
chr8_+_19171128 0.29 ENST00000265807.3
SH2D4A
SH2 domain containing 4A
chr6_-_39197226 0.29 ENST00000359534.3
KCNK5
potassium channel, subfamily K, member 5
chr6_-_31697255 0.29 ENST00000436437.1
DDAH2
dimethylarginine dimethylaminohydrolase 2
chr8_+_33342268 0.29 ENST00000360128.6
MAK16
MAK16 homolog (S. cerevisiae)
chr11_+_74660278 0.29 ENST00000263672.6
ENST00000530257.1
ENST00000526361.1
ENST00000532972.1
SPCS2
signal peptidase complex subunit 2 homolog (S. cerevisiae)
chr2_+_33701707 0.29 ENST00000425210.1
ENST00000444784.1
ENST00000423159.1
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr11_+_34999328 0.29 ENST00000526309.1
PDHX
pyruvate dehydrogenase complex, component X
chr1_-_149889382 0.29 ENST00000369145.1
ENST00000369146.3
SV2A
synaptic vesicle glycoprotein 2A
chr4_+_114214125 0.29 ENST00000509550.1
ANK2
ankyrin 2, neuronal
chr20_-_43133491 0.29 ENST00000411544.1
SERINC3
serine incorporator 3
chr6_-_116833500 0.29 ENST00000356128.4
TRAPPC3L
trafficking protein particle complex 3-like
chr17_+_68165657 0.29 ENST00000243457.3
KCNJ2
potassium inwardly-rectifying channel, subfamily J, member 2
chr6_+_143771934 0.28 ENST00000367592.1
PEX3
peroxisomal biogenesis factor 3
chr16_-_18441131 0.28 ENST00000339303.5
NPIPA8
nuclear pore complex interacting protein family, member A8
chr12_-_105352080 0.28 ENST00000433540.1
SLC41A2
solute carrier family 41 (magnesium transporter), member 2
chr13_+_37574678 0.28 ENST00000389704.3
EXOSC8
exosome component 8
chr6_-_41673552 0.28 ENST00000419574.1
ENST00000445214.1
TFEB
transcription factor EB
chr16_+_71929397 0.28 ENST00000537613.1
ENST00000424485.2
ENST00000606369.1
ENST00000329908.8
ENST00000538850.1
ENST00000541918.1
ENST00000534994.1
ENST00000378798.5
ENST00000539186.1
IST1
increased sodium tolerance 1 homolog (yeast)
chr2_+_86116396 0.28 ENST00000455121.3
AC105053.4
AC105053.4
chr1_+_46379254 0.27 ENST00000372008.2
MAST2
microtubule associated serine/threonine kinase 2
chr12_-_68845165 0.27 ENST00000360485.3
ENST00000441255.2
RP11-81H14.2
RP11-81H14.2
chr6_-_26250835 0.27 ENST00000446824.2
HIST1H3F
histone cluster 1, H3f
chr8_-_99837856 0.27 ENST00000518165.1
ENST00000419617.2
STK3
serine/threonine kinase 3
chr19_-_43702231 0.27 ENST00000597374.1
ENST00000599371.1
PSG4
pregnancy specific beta-1-glycoprotein 4
chr6_-_11382478 0.26 ENST00000397378.3
ENST00000513989.1
ENST00000508546.1
ENST00000504387.1
NEDD9
neural precursor cell expressed, developmentally down-regulated 9
chr6_+_10528560 0.26 ENST00000379597.3
GCNT2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr12_+_16500599 0.26 ENST00000535309.1
ENST00000540056.1
ENST00000396209.1
ENST00000540126.1
MGST1
microsomal glutathione S-transferase 1
chr19_-_17185848 0.26 ENST00000593360.1
HAUS8
HAUS augmin-like complex, subunit 8
chr8_-_12293852 0.25 ENST00000262365.4
ENST00000351291.4
ENST00000309608.5
ENST00000527331.1
ENST00000532480.1
ENST00000393715.3
FAM86B2
family with sequence similarity 86, member B2
chr11_+_47270436 0.25 ENST00000395397.3
ENST00000405576.1
NR1H3
nuclear receptor subfamily 1, group H, member 3
chr7_-_76255444 0.25 ENST00000454397.1
POMZP3
POM121 and ZP3 fusion
chr7_+_99102267 0.25 ENST00000326775.5
ENST00000451158.1
ZKSCAN5
zinc finger with KRAB and SCAN domains 5
chr5_+_68513557 0.25 ENST00000256441.4
MRPS36
mitochondrial ribosomal protein S36
chr3_-_33700589 0.25 ENST00000461133.3
ENST00000496954.2
CLASP2
cytoplasmic linker associated protein 2
chr10_-_51130715 0.25 ENST00000402038.3
PARG
poly (ADP-ribose) glycohydrolase
chr7_+_99102573 0.24 ENST00000394170.2
ZKSCAN5
zinc finger with KRAB and SCAN domains 5
chr17_+_7477040 0.24 ENST00000581384.1
ENST00000577929.1
EIF4A1
eukaryotic translation initiation factor 4A1
chr16_+_56970567 0.24 ENST00000563911.1
HERPUD1
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1

Network of associatons between targets according to the STRING database.

First level regulatory network of TCF21

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.0 GO:2000775 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662) response to DDT(GO:0046680) histone H3-S10 phosphorylation involved in chromosome condensation(GO:2000775)
0.7 1.3 GO:0032354 response to follicle-stimulating hormone(GO:0032354)
0.5 1.8 GO:0042369 vitamin D catabolic process(GO:0042369)
0.4 1.2 GO:0051685 maintenance of ER location(GO:0051685)
0.3 1.3 GO:0008355 olfactory learning(GO:0008355)
0.3 2.4 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.2 1.4 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.2 1.1 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.2 1.3 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.2 0.7 GO:0036378 calcitriol biosynthetic process from calciol(GO:0036378)
0.2 0.7 GO:0097069 cellular response to thyroxine stimulus(GO:0097069) cellular response to L-phenylalanine derivative(GO:1904387)
0.2 0.8 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.2 0.5 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.1 0.4 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.1 1.1 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.1 0.5 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
0.1 0.4 GO:0007057 spindle assembly involved in female meiosis I(GO:0007057)
0.1 0.5 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.1 1.1 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.1 0.5 GO:2001183 negative regulation of interleukin-10 secretion(GO:2001180) negative regulation of interleukin-12 secretion(GO:2001183)
0.1 0.3 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.1 1.6 GO:0006108 malate metabolic process(GO:0006108)
0.1 1.6 GO:0030321 transepithelial chloride transport(GO:0030321)
0.1 1.0 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1 1.4 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.1 0.6 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.1 0.5 GO:0090341 negative regulation of secretion of lysosomal enzymes(GO:0090341)
0.1 2.7 GO:0032060 bleb assembly(GO:0032060)
0.1 0.5 GO:0006574 valine catabolic process(GO:0006574)
0.1 0.5 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1 1.5 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.1 0.4 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.1 0.7 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.1 0.4 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.1 1.4 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.1 0.3 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.1 0.5 GO:0006041 glucosamine metabolic process(GO:0006041)
0.1 0.2 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.1 0.2 GO:1904346 positive regulation of growth rate(GO:0040010) regulation of gastric mucosal blood circulation(GO:1904344) positive regulation of gastric mucosal blood circulation(GO:1904346) gastric mucosal blood circulation(GO:1990768)
0.1 0.3 GO:0000459 exonucleolytic trimming involved in rRNA processing(GO:0000459) exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000467) U1 snRNA 3'-end processing(GO:0034473) U4 snRNA 3'-end processing(GO:0034475) U5 snRNA 3'-end processing(GO:0034476) nuclear polyadenylation-dependent tRNA catabolic process(GO:0071038)
0.1 0.3 GO:0036115 fatty-acyl-CoA catabolic process(GO:0036115)
0.1 1.0 GO:0042908 xenobiotic transport(GO:0042908)
0.1 0.2 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.1 2.6 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.1 0.2 GO:0034553 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.1 0.3 GO:0036371 protein localization to T-tubule(GO:0036371)
0.1 0.3 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.1 0.4 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.1 0.6 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.1 0.3 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.1 0.2 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 0.4 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.0 0.6 GO:0071169 establishment of protein localization to chromatin(GO:0071169)
0.0 0.3 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 0.4 GO:1902044 regulation of Fas signaling pathway(GO:1902044)
0.0 1.0 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.0 0.5 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.3 GO:0035803 egg coat formation(GO:0035803)
0.0 0.3 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 1.8 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.1 GO:0019085 early viral transcription(GO:0019085)
0.0 0.1 GO:1904647 response to rotenone(GO:1904647)
0.0 0.3 GO:0009597 detection of virus(GO:0009597)
0.0 0.1 GO:0006258 UDP-glucose catabolic process(GO:0006258)
0.0 0.2 GO:0036496 regulation of translational initiation by eIF2 alpha dephosphorylation(GO:0036496)
0.0 0.1 GO:0033292 T-tubule organization(GO:0033292)
0.0 0.3 GO:0032439 endosome localization(GO:0032439)
0.0 0.5 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.0 0.3 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.3 GO:0014052 regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.0 0.4 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.0 0.5 GO:1902916 positive regulation of protein polyubiquitination(GO:1902916)
0.0 0.4 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.0 0.5 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.1 GO:0070781 response to biotin(GO:0070781)
0.0 0.3 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.3 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 0.4 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.5 GO:0006527 arginine catabolic process(GO:0006527)
0.0 0.6 GO:0071360 cellular response to exogenous dsRNA(GO:0071360)
0.0 0.7 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.0 0.1 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228)
0.0 0.1 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.0 0.1 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
0.0 0.9 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.2 GO:0051122 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.1 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.4 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 0.7 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.0 0.6 GO:0051775 response to redox state(GO:0051775)
0.0 0.3 GO:0009838 abscission(GO:0009838)
0.0 0.3 GO:0042373 vitamin K metabolic process(GO:0042373)
0.0 0.1 GO:0060023 soft palate development(GO:0060023)
0.0 0.2 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.0 0.1 GO:0032185 septin cytoskeleton organization(GO:0032185)
0.0 0.2 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.3 GO:0034465 response to carbon monoxide(GO:0034465)
0.0 0.3 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.0 0.3 GO:0045075 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.0 0.5 GO:0061339 establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.0 1.2 GO:0048286 lung alveolus development(GO:0048286)
0.0 0.6 GO:0032201 telomere maintenance via semi-conservative replication(GO:0032201)
0.0 0.2 GO:0048194 Golgi vesicle budding(GO:0048194)
0.0 0.1 GO:1902283 negative regulation of primary amine oxidase activity(GO:1902283)
0.0 0.3 GO:1903800 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148) positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0 0.1 GO:0060151 peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
0.0 0.5 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.4 GO:0044130 negative regulation of growth of symbiont in host(GO:0044130)
0.0 0.2 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 0.1 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.0 0.2 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.2 GO:0060050 positive regulation of protein glycosylation(GO:0060050)
0.0 0.9 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 0.0 GO:0021650 vestibulocochlear nerve formation(GO:0021650)
0.0 0.2 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.0 GO:0038109 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109)
0.0 1.0 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.1 GO:0031438 negative regulation of mRNA cleavage(GO:0031438) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.0 0.4 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.1 GO:0001808 regulation of type IV hypersensitivity(GO:0001807) negative regulation of type IV hypersensitivity(GO:0001808)
0.0 0.1 GO:0009386 translational attenuation(GO:0009386)
0.0 0.2 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.0 0.0 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.0 0.4 GO:0032292 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0 0.1 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.0 0.6 GO:0044243 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.0 0.7 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.1 GO:0060157 urinary bladder development(GO:0060157)
0.0 0.5 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.2 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.1 GO:2000672 cellular response to sorbitol(GO:0072709) negative regulation of motor neuron apoptotic process(GO:2000672)
0.0 0.1 GO:0071503 positive regulation of lipoprotein particle clearance(GO:0010986) response to heparin(GO:0071503)
0.0 0.1 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.0 0.1 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.5 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.0 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.2 0.7 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.2 0.7 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.2 1.4 GO:0005579 membrane attack complex(GO:0005579)
0.2 0.7 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.1 0.4 GO:0042585 germinal vesicle(GO:0042585)
0.1 0.6 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.1 0.6 GO:0005587 collagen type IV trimer(GO:0005587)
0.1 0.2 GO:0005602 complement component C1 complex(GO:0005602)
0.1 2.6 GO:0043218 compact myelin(GO:0043218)
0.1 0.4 GO:0035061 interchromatin granule(GO:0035061)
0.1 1.1 GO:0032059 bleb(GO:0032059)
0.1 0.2 GO:0045257 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.1 0.8 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.1 1.1 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.1 0.5 GO:0005787 signal peptidase complex(GO:0005787)
0.1 0.6 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.9 GO:0000235 astral microtubule(GO:0000235) aster(GO:0005818)
0.0 0.7 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.6 GO:0070652 HAUS complex(GO:0070652)
0.0 0.2 GO:1990037 Lewy body core(GO:1990037)
0.0 1.3 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.4 GO:0000798 nuclear cohesin complex(GO:0000798)
0.0 1.0 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.2 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.6 GO:0036038 MKS complex(GO:0036038)
0.0 0.3 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.1 GO:0016342 catenin complex(GO:0016342)
0.0 0.8 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.1 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.0 0.4 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.4 GO:0070938 contractile ring(GO:0070938)
0.0 0.2 GO:0061617 MICOS complex(GO:0061617)
0.0 0.4 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.4 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 1.8 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.4 GO:0042555 MCM complex(GO:0042555)
0.0 1.3 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.2 GO:0045179 apical cortex(GO:0045179)
0.0 0.2 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.1 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.0 0.7 GO:0000145 exocyst(GO:0000145)
0.0 0.4 GO:0043203 axon hillock(GO:0043203)
0.0 0.3 GO:0030008 TRAPP complex(GO:0030008)
0.0 2.2 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.0 0.5 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.4 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.1 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.3 GO:0090543 Flemming body(GO:0090543)
0.0 0.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.2 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.5 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.5 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 1.0 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.2 GO:0042587 glycogen granule(GO:0042587)
0.0 1.2 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.0 0.3 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.4 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.4 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.1 GO:0005869 dynactin complex(GO:0005869)
0.0 0.1 GO:0002169 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
0.0 0.6 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.1 GO:1990635 proximal dendrite(GO:1990635)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.0 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.4 1.6 GO:0047860 diiodophenylpyruvate reductase activity(GO:0047860)
0.3 0.7 GO:0070643 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.3 2.4 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
0.2 1.3 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.2 1.0 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.2 0.7 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.2 1.6 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.2 1.4 GO:0038051 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.1 0.5 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.1 0.6 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.1 0.3 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.1 0.3 GO:0090541 MIT domain binding(GO:0090541)
0.1 0.6 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.1 0.7 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.1 1.0 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.1 0.2 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.1 0.6 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.1 0.2 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.1 0.5 GO:0016403 dimethylargininase activity(GO:0016403)
0.1 0.2 GO:0031768 growth hormone-releasing hormone activity(GO:0016608) ghrelin receptor binding(GO:0031768)
0.1 1.8 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.1 0.3 GO:0070051 fibrinogen binding(GO:0070051)
0.1 0.6 GO:0008158 hedgehog receptor activity(GO:0008158)
0.1 0.3 GO:0016900 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.1 1.1 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 0.5 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.1 0.9 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 0.6 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.1 0.5 GO:0032810 sterol response element binding(GO:0032810)
0.0 1.1 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.3 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.0 0.1 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.0 1.0 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 1.0 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.2 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.0 0.4 GO:0035174 histone serine kinase activity(GO:0035174)
0.0 0.5 GO:0030274 LIM domain binding(GO:0030274)
0.0 1.3 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.4 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.4 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.3 GO:0035500 MH2 domain binding(GO:0035500)
0.0 0.3 GO:0034603 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.0 0.8 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 1.4 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.4 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 1.4 GO:0008009 chemokine activity(GO:0008009)
0.0 0.5 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.3 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.9 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.2 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.0 0.4 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.3 GO:0032190 acrosin binding(GO:0032190)
0.0 0.2 GO:0043426 MRF binding(GO:0043426)
0.0 0.5 GO:0043295 glutathione binding(GO:0043295)
0.0 0.4 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.4 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.6 GO:0016289 CoA hydrolase activity(GO:0016289)
0.0 1.3 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.0 0.8 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.0 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.0 0.1 GO:0045155 electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155)
0.0 0.6 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.5 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.2 GO:0008428 ribonuclease inhibitor activity(GO:0008428)
0.0 0.1 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.0 0.9 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.1 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.1 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.0 0.1 GO:0052593 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.0 0.3 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.0 0.0 GO:0030395 lactose binding(GO:0030395)
0.0 1.0 GO:0019894 kinesin binding(GO:0019894)
0.0 0.2 GO:0009374 biotin binding(GO:0009374)
0.0 0.0 GO:0098808 mRNA cap binding(GO:0098808)
0.0 0.1 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.8 GO:0004532 exoribonuclease activity(GO:0004532)
0.0 0.2 GO:0032183 SUMO binding(GO:0032183)
0.0 0.1 GO:0035473 lipase binding(GO:0035473)
0.0 0.4 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.1 GO:0071253 connexin binding(GO:0071253)
0.0 0.5 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.2 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.1 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.2 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.1 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 0.4 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.3 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 4.0 PID PLK1 PATHWAY PLK1 signaling events
0.0 1.3 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.6 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 1.3 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.6 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 1.1 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 1.8 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.1 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 1.5 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.4 PID ATR PATHWAY ATR signaling pathway
0.0 0.8 PID AURORA A PATHWAY Aurora A signaling
0.0 0.6 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.4 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.9 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.7 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.5 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.6 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 0.5 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.8 PID INSULIN PATHWAY Insulin Pathway
0.0 0.7 NABA COLLAGENS Genes encoding collagen proteins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.3 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 1.8 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.1 1.6 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 1.3 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.1 0.8 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1 1.0 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.1 2.4 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.1 2.5 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 2.6 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.5 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 1.6 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 1.4 REACTOME KINESINS Genes involved in Kinesins
0.0 0.7 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 2.0 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.6 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.0 0.6 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.4 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 1.2 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.4 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 1.0 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.7 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.3 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 1.2 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.6 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 1.1 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.4 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.3 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 1.1 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 1.0 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.6 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 1.1 REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT Genes involved in p53-Independent G1/S DNA damage checkpoint
0.0 0.6 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.0 0.4 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.3 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.3 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.3 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits