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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for TCF7

Z-value: 0.50

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Transcription factors associated with TCF7

Gene Symbol Gene ID Gene Info
TCF7
ENSG00000081059.15 transcription factor 7

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TCF7hg19_v2_chr5_+_133451254_133451316-0.408.0e-02Click!

Activity profile of TCF7 motif

Sorted Z-values of TCF7 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_151344172 0.94 ENST00000375734.2
ENST00000263895.4
ENST00000454202.1
RND3
Rho family GTPase 3
chr17_-_20946710 0.92 ENST00000584538.1
USP22
ubiquitin specific peptidase 22
chr11_-_10829851 0.77 ENST00000532082.1
EIF4G2
eukaryotic translation initiation factor 4 gamma, 2
chr3_-_167813132 0.77 ENST00000309027.4
GOLIM4
golgi integral membrane protein 4
chr7_-_30009542 0.76 ENST00000438497.1
SCRN1
secernin 1
chr3_-_197024394 0.65 ENST00000434148.1
ENST00000412364.2
ENST00000436682.1
ENST00000456699.2
ENST00000392380.2
DLG1
discs, large homolog 1 (Drosophila)
chr17_-_56065484 0.60 ENST00000581208.1
VEZF1
vascular endothelial zinc finger 1
chr15_-_35280426 0.57 ENST00000559564.1
ENST00000356321.4
ZNF770
zinc finger protein 770
chr4_+_71859156 0.55 ENST00000286648.5
ENST00000504730.1
ENST00000504952.1
DCK
deoxycytidine kinase
chr11_-_3013316 0.55 ENST00000430811.1
NAP1L4
nucleosome assembly protein 1-like 4
chr11_+_65851443 0.54 ENST00000533756.1
PACS1
phosphofurin acidic cluster sorting protein 1
chr8_-_101962777 0.54 ENST00000395951.3
YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr11_-_3013482 0.53 ENST00000529361.1
ENST00000528968.1
ENST00000534372.1
ENST00000531291.1
ENST00000526842.1
NAP1L4
nucleosome assembly protein 1-like 4
chr5_-_157002749 0.53 ENST00000517905.1
ENST00000430702.2
ENST00000394020.1
ADAM19
ADAM metallopeptidase domain 19
chr3_-_167813672 0.53 ENST00000470487.1
GOLIM4
golgi integral membrane protein 4
chr15_+_63414760 0.52 ENST00000557972.1
LACTB
lactamase, beta
chr11_-_10830463 0.49 ENST00000527419.1
ENST00000530211.1
ENST00000530702.1
ENST00000524932.1
ENST00000532570.1
EIF4G2
eukaryotic translation initiation factor 4 gamma, 2
chr19_+_45281118 0.47 ENST00000270279.3
ENST00000341505.4
CBLC
Cbl proto-oncogene C, E3 ubiquitin protein ligase
chr7_+_55086703 0.47 ENST00000455089.1
ENST00000342916.3
ENST00000344576.2
ENST00000420316.2
EGFR
epidermal growth factor receptor
chr5_+_34757309 0.46 ENST00000397449.1
RAI14
retinoic acid induced 14
chr17_-_56065540 0.46 ENST00000583932.1
VEZF1
vascular endothelial zinc finger 1
chr4_-_140477928 0.45 ENST00000274031.3
SETD7
SET domain containing (lysine methyltransferase) 7
chr2_+_158114051 0.45 ENST00000259056.4
GALNT5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)
chr14_+_85996507 0.44 ENST00000554746.1
FLRT2
fibronectin leucine rich transmembrane protein 2
chr17_+_75447326 0.43 ENST00000591088.1
SEPT9
septin 9
chr10_-_14613968 0.41 ENST00000488576.1
ENST00000472095.1
FAM107B
family with sequence similarity 107, member B
chr1_-_153029980 0.41 ENST00000392653.2
SPRR2A
small proline-rich protein 2A
chr7_-_107643567 0.41 ENST00000393559.1
ENST00000439976.1
ENST00000393560.1
LAMB1
laminin, beta 1
chr3_+_111578027 0.40 ENST00000431670.2
ENST00000412622.1
PHLDB2
pleckstrin homology-like domain, family B, member 2
chr4_-_7873713 0.40 ENST00000382543.3
AFAP1
actin filament associated protein 1
chr7_-_80548667 0.40 ENST00000265361.3
SEMA3C
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr12_-_46385811 0.39 ENST00000419565.2
SCAF11
SR-related CTD-associated factor 11
chr16_+_68678739 0.39 ENST00000264012.4
CDH3
cadherin 3, type 1, P-cadherin (placental)
chr7_+_23286182 0.39 ENST00000258733.4
ENST00000381990.2
ENST00000409458.3
ENST00000539136.1
ENST00000453162.2
GPNMB
glycoprotein (transmembrane) nmb
chr4_-_74486347 0.38 ENST00000342081.3
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr1_-_153013588 0.38 ENST00000360379.3
SPRR2D
small proline-rich protein 2D
chr1_+_68150744 0.38 ENST00000370986.4
ENST00000370985.3
GADD45A
growth arrest and DNA-damage-inducible, alpha
chr10_+_75668916 0.38 ENST00000481390.1
PLAU
plasminogen activator, urokinase
chr7_-_30008849 0.38 ENST00000409497.1
SCRN1
secernin 1
chr11_-_3013497 0.37 ENST00000448187.1
ENST00000532325.2
ENST00000399614.2
NAP1L4
nucleosome assembly protein 1-like 4
chr10_-_24911746 0.37 ENST00000320481.6
ARHGAP21
Rho GTPase activating protein 21
chr7_+_99613212 0.37 ENST00000426572.1
ENST00000535170.1
ZKSCAN1
zinc finger with KRAB and SCAN domains 1
chr19_+_12273866 0.37 ENST00000425827.1
ENST00000439995.1
ENST00000343979.4
ENST00000398616.2
ENST00000418338.1
ZNF136
zinc finger protein 136
chr4_+_87515454 0.36 ENST00000427191.2
ENST00000436978.1
ENST00000502971.1
PTPN13
protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
chr3_+_111578583 0.36 ENST00000478922.1
ENST00000477695.1
PHLDB2
pleckstrin homology-like domain, family B, member 2
chr7_+_134576317 0.36 ENST00000424922.1
ENST00000495522.1
CALD1
caldesmon 1
chr12_+_104359614 0.36 ENST00000266775.9
ENST00000544861.1
TDG
thymine-DNA glycosylase
chr4_-_140477910 0.36 ENST00000404104.3
SETD7
SET domain containing (lysine methyltransferase) 7
chr14_+_85996471 0.35 ENST00000330753.4
FLRT2
fibronectin leucine rich transmembrane protein 2
chr3_+_111578131 0.35 ENST00000498699.1
PHLDB2
pleckstrin homology-like domain, family B, member 2
chr12_-_49582593 0.35 ENST00000295766.5
TUBA1A
tubulin, alpha 1a
chr10_-_14614095 0.34 ENST00000482277.1
ENST00000378462.1
FAM107B
family with sequence similarity 107, member B
chr15_+_64752927 0.34 ENST00000416172.1
ZNF609
zinc finger protein 609
chr8_+_27629459 0.34 ENST00000523566.1
ESCO2
establishment of sister chromatid cohesion N-acetyltransferase 2
chr17_-_57229155 0.34 ENST00000584089.1
SKA2
spindle and kinetochore associated complex subunit 2
chr12_-_49581152 0.33 ENST00000550811.1
TUBA1A
tubulin, alpha 1a
chr7_+_151791095 0.32 ENST00000422997.2
GALNT11
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11)
chr12_+_27677085 0.31 ENST00000545334.1
ENST00000540114.1
ENST00000537927.1
ENST00000318304.8
ENST00000535047.1
ENST00000542629.1
ENST00000228425.6
PPFIBP1
PTPRF interacting protein, binding protein 1 (liprin beta 1)
chr2_-_208031542 0.30 ENST00000423015.1
KLF7
Kruppel-like factor 7 (ubiquitous)
chr9_-_35071960 0.30 ENST00000417448.1
VCP
valosin containing protein
chr12_+_6309963 0.30 ENST00000382515.2
CD9
CD9 molecule
chr2_+_46926326 0.30 ENST00000394861.2
SOCS5
suppressor of cytokine signaling 5
chr9_+_103189536 0.30 ENST00000374885.1
MSANTD3
Myb/SANT-like DNA-binding domain containing 3
chr1_-_62785054 0.30 ENST00000371153.4
KANK4
KN motif and ankyrin repeat domains 4
chr5_-_157286104 0.30 ENST00000530742.1
ENST00000523908.1
ENST00000523094.1
ENST00000296951.5
ENST00000411809.2
CLINT1
clathrin interactor 1
chr9_+_125703282 0.29 ENST00000373647.4
ENST00000402311.1
RABGAP1
RAB GTPase activating protein 1
chr5_+_149865838 0.29 ENST00000519157.1
NDST1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr22_-_47134077 0.29 ENST00000541677.1
ENST00000216264.8
CERK
ceramide kinase
chr9_+_91003271 0.29 ENST00000375859.3
ENST00000541629.1
SPIN1
spindlin 1
chr10_-_14614311 0.28 ENST00000479731.1
ENST00000468492.1
FAM107B
family with sequence similarity 107, member B
chr13_+_42846272 0.27 ENST00000025301.2
AKAP11
A kinase (PRKA) anchor protein 11
chr8_-_134511587 0.27 ENST00000523855.1
ENST00000523854.1
ST3GAL1
ST3 beta-galactoside alpha-2,3-sialyltransferase 1
chr7_+_151791037 0.26 ENST00000419245.1
GALNT11
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11)
chr17_+_31254892 0.26 ENST00000394642.3
ENST00000579849.1
TMEM98
transmembrane protein 98
chr1_-_209824643 0.26 ENST00000391911.1
ENST00000415782.1
LAMB3
laminin, beta 3
chr2_+_69240302 0.26 ENST00000303714.4
ANTXR1
anthrax toxin receptor 1
chr15_+_36871983 0.26 ENST00000437989.2
ENST00000569302.1
C15orf41
chromosome 15 open reading frame 41
chr17_+_36584662 0.26 ENST00000431231.2
ENST00000437668.3
ARHGAP23
Rho GTPase activating protein 23
chr9_+_125795788 0.26 ENST00000373643.5
RABGAP1
RAB GTPase activating protein 1
chr7_+_151791074 0.25 ENST00000447796.1
GALNT11
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11)
chr6_-_112408661 0.25 ENST00000368662.5
TUBE1
tubulin, epsilon 1
chr6_-_27440460 0.25 ENST00000377419.1
ZNF184
zinc finger protein 184
chr5_+_43603229 0.25 ENST00000344920.4
ENST00000512996.2
NNT
nicotinamide nucleotide transhydrogenase
chr10_+_99332198 0.25 ENST00000307518.5
ENST00000298808.5
ENST00000370655.1
ANKRD2
ankyrin repeat domain 2 (stretch responsive muscle)
chr11_-_87908600 0.25 ENST00000531138.1
ENST00000526372.1
ENST00000243662.6
RAB38
RAB38, member RAS oncogene family
chr11_-_122930121 0.25 ENST00000524552.1
HSPA8
heat shock 70kDa protein 8
chr2_-_208031943 0.24 ENST00000421199.1
ENST00000457962.1
KLF7
Kruppel-like factor 7 (ubiquitous)
chr11_-_125365435 0.24 ENST00000524435.1
FEZ1
fasciculation and elongation protein zeta 1 (zygin I)
chr17_+_31255165 0.24 ENST00000578289.1
ENST00000439138.1
TMEM98
transmembrane protein 98
chr15_+_74218787 0.24 ENST00000261921.7
LOXL1
lysyl oxidase-like 1
chr1_+_59762642 0.24 ENST00000371218.4
ENST00000303721.7
FGGY
FGGY carbohydrate kinase domain containing
chr1_+_166808667 0.24 ENST00000537173.1
ENST00000536514.1
ENST00000449930.1
POGK
pogo transposable element with KRAB domain
chr11_+_12302492 0.24 ENST00000533534.1
MICALCL
MICAL C-terminal like
chr6_+_64346386 0.24 ENST00000509330.1
PHF3
PHD finger protein 3
chr3_+_111717511 0.24 ENST00000478951.1
ENST00000393917.2
TAGLN3
transgelin 3
chr6_-_27440837 0.24 ENST00000211936.6
ZNF184
zinc finger protein 184
chr5_-_160365601 0.23 ENST00000518580.1
ENST00000518301.1
RP11-109J4.1
RP11-109J4.1
chr12_-_109915098 0.23 ENST00000542858.1
ENST00000542262.1
ENST00000424763.2
KCTD10
potassium channel tetramerization domain containing 10
chr11_-_125366018 0.23 ENST00000527534.1
FEZ1
fasciculation and elongation protein zeta 1 (zygin I)
chr14_-_85996332 0.23 ENST00000380722.1
RP11-497E19.1
RP11-497E19.1
chr1_-_6546001 0.23 ENST00000400913.1
PLEKHG5
pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr5_-_79287060 0.22 ENST00000512560.1
ENST00000509852.1
ENST00000512528.1
MTX3
metaxin 3
chr12_+_121131970 0.22 ENST00000535656.1
MLEC
malectin
chrX_-_148676974 0.22 ENST00000524178.1
HSFX2
heat shock transcription factor family, X linked 2
chrX_+_135618258 0.22 ENST00000440515.1
ENST00000456412.1
VGLL1
vestigial like 1 (Drosophila)
chr4_+_95128748 0.21 ENST00000359052.4
SMARCAD1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr10_-_14614122 0.21 ENST00000378465.3
ENST00000452706.2
ENST00000378458.2
FAM107B
family with sequence similarity 107, member B
chr17_+_30813576 0.21 ENST00000313401.3
CDK5R1
cyclin-dependent kinase 5, regulatory subunit 1 (p35)
chr7_+_107384142 0.21 ENST00000440859.3
CBLL1
Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase
chr12_+_69080734 0.21 ENST00000378905.2
NUP107
nucleoporin 107kDa
chr9_+_103189405 0.20 ENST00000395067.2
MSANTD3
Myb/SANT-like DNA-binding domain containing 3
chr1_-_109935819 0.20 ENST00000538502.1
SORT1
sortilin 1
chr2_+_219745020 0.20 ENST00000258411.3
WNT10A
wingless-type MMTV integration site family, member 10A
chr19_+_10765614 0.20 ENST00000589283.1
ILF3
interleukin enhancer binding factor 3, 90kDa
chr5_-_157002775 0.20 ENST00000257527.4
ADAM19
ADAM metallopeptidase domain 19
chrX_+_100663243 0.20 ENST00000316594.5
HNRNPH2
heterogeneous nuclear ribonucleoprotein H2 (H')
chr3_+_14989186 0.20 ENST00000435454.1
ENST00000323373.6
NR2C2
nuclear receptor subfamily 2, group C, member 2
chr15_+_52043758 0.20 ENST00000249700.4
ENST00000539962.2
TMOD2
tropomodulin 2 (neuronal)
chr1_+_2043086 0.20 ENST00000470986.1
PRKCZ
protein kinase C, zeta
chr16_+_8806800 0.20 ENST00000561870.1
ENST00000396600.2
ABAT
4-aminobutyrate aminotransferase
chr3_+_159570722 0.20 ENST00000482804.1
SCHIP1
schwannomin interacting protein 1
chr8_-_42358742 0.20 ENST00000517366.1
SLC20A2
solute carrier family 20 (phosphate transporter), member 2
chr12_-_67197760 0.20 ENST00000539540.1
ENST00000540433.1
ENST00000541947.1
ENST00000538373.1
GRIP1
glutamate receptor interacting protein 1
chr1_+_16090914 0.20 ENST00000441801.2
FBLIM1
filamin binding LIM protein 1
chr12_+_8849773 0.20 ENST00000541044.1
RIMKLB
ribosomal modification protein rimK-like family member B
chr3_+_118892411 0.20 ENST00000479520.1
ENST00000494855.1
UPK1B
uroplakin 1B
chr17_-_65242063 0.19 ENST00000581159.1
HELZ
helicase with zinc finger
chr7_+_89975979 0.19 ENST00000257659.8
ENST00000222511.6
ENST00000417207.1
GTPBP10
GTP-binding protein 10 (putative)
chr11_-_85430204 0.19 ENST00000389958.3
ENST00000527794.1
SYTL2
synaptotagmin-like 2
chr2_+_24150180 0.19 ENST00000404924.1
UBXN2A
UBX domain protein 2A
chr16_+_57673348 0.19 ENST00000567915.1
ENST00000564103.1
ENST00000562467.1
GPR56
G protein-coupled receptor 56
chr2_-_36825281 0.19 ENST00000405912.3
ENST00000379245.4
FEZ2
fasciculation and elongation protein zeta 2 (zygin II)
chr15_+_36871806 0.19 ENST00000566621.1
ENST00000564586.1
C15orf41
chromosome 15 open reading frame 41
chr3_+_12598563 0.19 ENST00000411987.1
ENST00000448482.1
MKRN2
makorin ring finger protein 2
chr19_+_10765699 0.19 ENST00000590009.1
ILF3
interleukin enhancer binding factor 3, 90kDa
chr11_-_85430088 0.18 ENST00000533057.1
ENST00000533892.1
SYTL2
synaptotagmin-like 2
chrX_+_148855726 0.18 ENST00000370416.4
HSFX1
heat shock transcription factor family, X linked 1
chr16_-_46723066 0.18 ENST00000299138.7
VPS35
vacuolar protein sorting 35 homolog (S. cerevisiae)
chr1_-_153113927 0.18 ENST00000368752.4
SPRR2B
small proline-rich protein 2B
chrX_-_55020511 0.18 ENST00000375006.3
ENST00000374992.2
PFKFB1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr5_-_16936340 0.18 ENST00000507288.1
ENST00000513610.1
MYO10
myosin X
chr7_+_134576151 0.18 ENST00000393118.2
CALD1
caldesmon 1
chr12_-_133405409 0.18 ENST00000545875.1
ENST00000456883.2
GOLGA3
golgin A3
chr4_-_100484825 0.18 ENST00000273962.3
ENST00000514547.1
ENST00000455368.2
TRMT10A
tRNA methyltransferase 10 homolog A (S. cerevisiae)
chr4_-_71705027 0.18 ENST00000545193.1
GRSF1
G-rich RNA sequence binding factor 1
chr9_-_21228221 0.18 ENST00000413767.2
IFNA17
interferon, alpha 17
chr11_-_33774944 0.17 ENST00000532057.1
ENST00000531080.1
FBXO3
F-box protein 3
chr8_+_56792355 0.17 ENST00000519728.1
LYN
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
chr1_+_182808474 0.17 ENST00000367549.3
DHX9
DEAH (Asp-Glu-Ala-His) box helicase 9
chr6_-_30684898 0.17 ENST00000422266.1
ENST00000416571.1
MDC1
mediator of DNA-damage checkpoint 1
chr3_+_111717600 0.17 ENST00000273368.4
TAGLN3
transgelin 3
chr8_+_95653840 0.17 ENST00000520385.1
ESRP1
epithelial splicing regulatory protein 1
chr17_-_34890037 0.17 ENST00000589404.1
MYO19
myosin XIX
chr2_+_172378757 0.17 ENST00000409484.1
ENST00000321348.4
ENST00000375252.3
CYBRD1
cytochrome b reductase 1
chr4_-_7069760 0.17 ENST00000264954.4
GRPEL1
GrpE-like 1, mitochondrial (E. coli)
chr4_-_71705060 0.17 ENST00000514161.1
GRSF1
G-rich RNA sequence binding factor 1
chr12_+_100594557 0.17 ENST00000546902.1
ENST00000552376.1
ENST00000551617.1
ACTR6
ARP6 actin-related protein 6 homolog (yeast)
chr4_+_89300158 0.17 ENST00000502870.1
HERC6
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
chr19_+_13134772 0.17 ENST00000587760.1
ENST00000585575.1
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr9_-_125675576 0.17 ENST00000373659.3
ZBTB6
zinc finger and BTB domain containing 6
chr17_+_31255023 0.17 ENST00000395149.2
ENST00000261713.4
TMEM98
transmembrane protein 98
chr17_+_57697246 0.17 ENST00000580081.1
ENST00000579456.1
CLTC
clathrin, heavy chain (Hc)
chr12_-_133464118 0.16 ENST00000540963.1
CHFR
checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase
chr12_+_21654714 0.16 ENST00000542038.1
ENST00000540141.1
ENST00000229314.5
GOLT1B
golgi transport 1B
chr3_+_111718036 0.16 ENST00000455401.2
TAGLN3
transgelin 3
chr12_+_104359576 0.16 ENST00000392872.3
ENST00000436021.2
TDG
thymine-DNA glycosylase
chr2_-_136288740 0.16 ENST00000264159.6
ENST00000536680.1
ZRANB3
zinc finger, RAN-binding domain containing 3
chr4_+_95128996 0.16 ENST00000457823.2
SMARCAD1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr22_-_26908343 0.16 ENST00000407431.1
ENST00000455080.1
ENST00000418876.1
ENST00000440258.1
ENST00000407148.1
ENST00000420242.1
ENST00000405938.1
ENST00000407690.1
TFIP11
tuftelin interacting protein 11
chr12_+_104359641 0.15 ENST00000537100.1
TDG
thymine-DNA glycosylase
chr7_-_19748640 0.15 ENST00000222567.5
TWISTNB
TWIST neighbor
chr19_+_57791806 0.15 ENST00000360338.3
ZNF460
zinc finger protein 460
chr17_-_74489215 0.15 ENST00000585701.1
ENST00000591192.1
ENST00000589526.1
RHBDF2
rhomboid 5 homolog 2 (Drosophila)
chr7_+_100663353 0.15 ENST00000306151.4
MUC17
mucin 17, cell surface associated
chr2_-_198299726 0.15 ENST00000409915.4
ENST00000487698.1
ENST00000414963.2
ENST00000335508.6
SF3B1
splicing factor 3b, subunit 1, 155kDa
chr16_-_46864955 0.15 ENST00000565112.1
C16orf87
chromosome 16 open reading frame 87
chrX_-_153599578 0.15 ENST00000360319.4
ENST00000344736.4
FLNA
filamin A, alpha
chr1_+_75198871 0.15 ENST00000479111.1
TYW3
tRNA-yW synthesizing protein 3 homolog (S. cerevisiae)
chr15_-_44116873 0.15 ENST00000267812.3
MFAP1
microfibrillar-associated protein 1
chr9_-_130639997 0.14 ENST00000373176.1
AK1
adenylate kinase 1
chr5_+_125935960 0.14 ENST00000297540.4
PHAX
phosphorylated adaptor for RNA export
chr14_-_23762777 0.14 ENST00000431326.2
HOMEZ
homeobox and leucine zipper encoding
chr15_+_57211318 0.14 ENST00000557947.1
TCF12
transcription factor 12
chr11_+_65999265 0.14 ENST00000528935.1
PACS1
phosphofurin acidic cluster sorting protein 1
chr21_+_39628852 0.14 ENST00000398938.2
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr14_-_35344093 0.14 ENST00000382422.2
BAZ1A
bromodomain adjacent to zinc finger domain, 1A
chr3_-_120068143 0.14 ENST00000295628.3
LRRC58
leucine rich repeat containing 58
chr19_+_1026566 0.14 ENST00000348419.3
ENST00000565096.2
ENST00000562958.2
ENST00000562075.2
ENST00000607102.1
CNN2
calponin 2
chr7_+_123469037 0.14 ENST00000489978.1
HYAL4
hyaluronoglucosaminidase 4
chr11_-_85430163 0.14 ENST00000529581.1
ENST00000533577.1
SYTL2
synaptotagmin-like 2
chr17_+_26989109 0.13 ENST00000314616.6
ENST00000347486.4
SUPT6H
suppressor of Ty 6 homolog (S. cerevisiae)
chr15_+_30918879 0.13 ENST00000428041.2
ARHGAP11B
Rho GTPase activating protein 11B
chr5_+_136070614 0.13 ENST00000502421.1
CTB-1I21.1
CTB-1I21.1
chr1_+_11072696 0.13 ENST00000240185.3
ENST00000476201.1
TARDBP
TAR DNA binding protein
chr10_-_104211294 0.13 ENST00000239125.1
C10orf95
chromosome 10 open reading frame 95
chr3_-_25824353 0.13 ENST00000427041.1
NGLY1
N-glycanase 1
chr15_+_52043813 0.13 ENST00000435126.2
TMOD2
tropomodulin 2 (neuronal)
chr22_+_21271714 0.13 ENST00000354336.3
CRKL
v-crk avian sarcoma virus CT10 oncogene homolog-like
chr1_+_16010779 0.13 ENST00000375799.3
ENST00000375793.2
PLEKHM2
pleckstrin homology domain containing, family M (with RUN domain) member 2
chr7_+_72395617 0.12 ENST00000434423.2
POM121
POM121 transmembrane nucleoporin

Network of associatons between targets according to the STRING database.

First level regulatory network of TCF7

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:1902544 regulation of DNA N-glycosylase activity(GO:1902544)
0.1 0.8 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.1 0.5 GO:0043006 activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
0.1 0.3 GO:0072387 flavin adenine dinucleotide metabolic process(GO:0072387)
0.1 0.4 GO:0032771 regulation of monophenol monooxygenase activity(GO:0032771) positive regulation of monophenol monooxygenase activity(GO:0032773) negative regulation of catagen(GO:0051796) regulation of hair cycle by canonical Wnt signaling pathway(GO:0060901) positive regulation of melanosome transport(GO:1902910)
0.1 0.4 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.1 0.3 GO:1901202 negative regulation of extracellular matrix assembly(GO:1901202)
0.1 0.2 GO:0070668 regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.1 0.2 GO:0021718 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.1 0.3 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.1 1.1 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.1 0.6 GO:1903764 regulation of potassium ion export across plasma membrane(GO:1903764)
0.1 0.8 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.1 0.2 GO:1903181 negative regulation of late endosome to lysosome transport(GO:1902823) regulation of dopamine biosynthetic process(GO:1903179) positive regulation of dopamine biosynthetic process(GO:1903181) negative regulation of protein catabolic process in the vacuole(GO:1904351) negative regulation of lysosomal protein catabolic process(GO:1905166)
0.1 0.2 GO:0018277 protein deamination(GO:0018277)
0.1 0.4 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.1 0.3 GO:0034421 post-translational protein acetylation(GO:0034421)
0.1 0.8 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.1 0.4 GO:0006740 NADPH regeneration(GO:0006740)
0.1 0.2 GO:1904875 regulation of DNA ligase activity(GO:1904875)
0.1 0.7 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.1 0.2 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.1 0.4 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.6 GO:2000291 regulation of myoblast proliferation(GO:2000291)
0.0 0.2 GO:0036292 DNA rewinding(GO:0036292)
0.0 0.2 GO:1902904 negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.0 0.2 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.0 0.2 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.0 0.2 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.0 0.2 GO:1902722 positive regulation of prolactin secretion(GO:1902722)
0.0 0.4 GO:0003350 pulmonary myocardium development(GO:0003350)
0.0 0.1 GO:0006408 snRNA export from nucleus(GO:0006408)
0.0 0.2 GO:1903232 melanosome assembly(GO:1903232)
0.0 0.2 GO:0035549 positive regulation of interferon-beta secretion(GO:0035549)
0.0 0.2 GO:0002386 immune response in mucosal-associated lymphoid tissue(GO:0002386)
0.0 0.5 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.0 0.5 GO:0090168 Golgi reassembly(GO:0090168)
0.0 1.0 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.3 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.1 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.0 0.1 GO:0046521 sphingoid catabolic process(GO:0046521)
0.0 0.1 GO:1901069 guanosine-containing compound catabolic process(GO:1901069)
0.0 0.2 GO:1903301 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.0 0.1 GO:1904815 negative regulation of protein localization to chromosome, telomeric region(GO:1904815)
0.0 0.6 GO:0043097 pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.0 0.2 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.0 0.5 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.3 GO:0006477 protein sulfation(GO:0006477)
0.0 0.1 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.0 0.2 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.1 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.0 0.1 GO:0061687 detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501)
0.0 0.1 GO:0051086 chaperone mediated protein folding independent of cofactor(GO:0051086)
0.0 0.6 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.6 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 0.1 GO:0010286 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.0 0.3 GO:0030913 fusion of sperm to egg plasma membrane(GO:0007342) paranodal junction assembly(GO:0030913)
0.0 0.2 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.0 0.4 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.1 GO:0072086 specification of loop of Henle identity(GO:0072086) pattern specification involved in metanephros development(GO:0072268)
0.0 0.2 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.2 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.1 GO:0006172 ADP biosynthetic process(GO:0006172)
0.0 0.1 GO:0090410 malonate catabolic process(GO:0090410)
0.0 0.2 GO:0048733 sebaceous gland development(GO:0048733)
0.0 0.1 GO:0031337 cellular response to phosphate starvation(GO:0016036) positive regulation of sulfur amino acid metabolic process(GO:0031337) positive regulation of homocysteine metabolic process(GO:0050668)
0.0 0.1 GO:0007161 calcium-independent cell-matrix adhesion(GO:0007161)
0.0 0.1 GO:0072092 ureteric bud invasion(GO:0072092)
0.0 0.4 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.1 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
0.0 0.1 GO:0070901 mitochondrial tRNA methylation(GO:0070901)
0.0 0.1 GO:0060017 parathyroid gland development(GO:0060017)
0.0 1.0 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.2 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.1 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.1 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.3 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.2 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.7 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 0.0 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.0 0.1 GO:1904693 midbrain morphogenesis(GO:1904693)
0.0 1.0 GO:0006968 cellular defense response(GO:0006968)
0.0 0.0 GO:1904530 negative regulation of actin filament binding(GO:1904530) negative regulation of actin binding(GO:1904617)
0.0 0.0 GO:0060577 pulmonary vein morphogenesis(GO:0060577)
0.0 0.0 GO:0097267 omega-hydroxylase P450 pathway(GO:0097267)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0097489 multivesicular body, internal vesicle lumen(GO:0097489)
0.1 0.3 GO:0043257 laminin-8 complex(GO:0043257)
0.1 1.1 GO:0045180 basal cortex(GO:0045180)
0.1 1.0 GO:0000124 SAGA complex(GO:0000124)
0.1 0.2 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.1 0.3 GO:0005726 perichromatin fibrils(GO:0005726)
0.1 0.3 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.0 0.2 GO:0031905 early endosome lumen(GO:0031905)
0.0 1.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.1 GO:0008623 CHRAC(GO:0008623)
0.0 0.6 GO:0097025 lateral loop(GO:0043219) MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.2 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
0.0 0.2 GO:0031523 Myb complex(GO:0031523)
0.0 0.2 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
0.0 0.5 GO:0030478 actin cap(GO:0030478)
0.0 0.2 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 0.2 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.0 0.2 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 0.2 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0 0.1 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.0 0.5 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.3 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.7 GO:0030137 COPI-coated vesicle(GO:0030137)
0.0 0.1 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.0 1.5 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.3 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.5 GO:0031105 septin complex(GO:0031105)
0.0 1.0 GO:0001533 cornified envelope(GO:0001533)
0.0 0.1 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
0.0 0.1 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.2 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.1 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.2 GO:0045179 apical cortex(GO:0045179)
0.0 0.0 GO:0005584 collagen type I trimer(GO:0005584)
0.0 0.4 GO:0031527 filopodium membrane(GO:0031527)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.1 0.4 GO:0016652 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.1 0.5 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 0.6 GO:0004137 deoxycytidine kinase activity(GO:0004137)
0.1 0.2 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.1 0.2 GO:0019150 D-ribulokinase activity(GO:0019150)
0.1 0.2 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.1 0.2 GO:0072591 citrate-L-glutamate ligase activity(GO:0072591)
0.1 0.2 GO:0035651 AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651)
0.1 0.3 GO:0036435 K48-linked polyubiquitin binding(GO:0036435)
0.1 0.2 GO:0045142 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116) DNA/RNA helicase activity(GO:0033677) triplex DNA binding(GO:0045142)
0.0 0.6 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.1 GO:0000224 peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity(GO:0000224)
0.0 0.3 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.3 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.0 0.2 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.0 0.2 GO:0003867 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.0 0.4 GO:0045545 syndecan binding(GO:0045545)
0.0 0.2 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.1 GO:1904713 beta-catenin destruction complex binding(GO:1904713)
0.0 1.0 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.0 0.4 GO:0001727 lipid kinase activity(GO:0001727)
0.0 1.1 GO:0005112 Notch binding(GO:0005112)
0.0 0.8 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.1 GO:0016649 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.0 0.4 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 0.2 GO:0043208 glycosphingolipid binding(GO:0043208)
0.0 0.2 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
0.0 0.1 GO:0001855 complement component C4b binding(GO:0001855)
0.0 0.2 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.0 0.2 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.0 1.1 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.2 GO:0070404 NADH binding(GO:0070404)
0.0 0.9 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.4 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.2 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.1 GO:0038025 reelin receptor activity(GO:0038025)
0.0 0.2 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 0.2 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.2 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.0 0.1 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.0 0.1 GO:0016429 tRNA (adenine) methyltransferase activity(GO:0016426) tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.0 0.1 GO:0043849 Ras palmitoyltransferase activity(GO:0043849)
0.0 0.1 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.0 1.6 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.4 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.4 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.2 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.1 GO:0090409 malonyl-CoA synthetase activity(GO:0090409)
0.0 0.2 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.2 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.5 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.3 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.1 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.0 0.2 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 1.1 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.5 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.1 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.0 GO:1990175 EH domain binding(GO:1990175)
0.0 0.1 GO:0051373 FATZ binding(GO:0051373)
0.0 0.2 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.8 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.2 PID IL5 PATHWAY IL5-mediated signaling events
0.0 1.4 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.3 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.9 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.7 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.6 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.6 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.8 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.5 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.0 1.8 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.5 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.3 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.4 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.1 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.1 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 1.6 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.4 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation