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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for TCF7L2

Z-value: 1.62

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Transcription factors associated with TCF7L2

Gene Symbol Gene ID Gene Info
TCF7L2
ENSG00000148737.11 transcription factor 7 like 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TCF7L2hg19_v2_chr10_+_114710211_114710229-0.551.1e-02Click!

Activity profile of TCF7L2 motif

Sorted Z-values of TCF7L2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr10_+_101542462 8.50 ENST00000370449.4
ENST00000370434.1
ABCC2
ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chr11_+_114128522 7.60 ENST00000535401.1
NNMT
nicotinamide N-methyltransferase
chr9_+_97766409 7.60 ENST00000425634.2
C9orf3
chromosome 9 open reading frame 3
chr1_-_153522562 7.59 ENST00000368714.1
S100A4
S100 calcium binding protein A4
chr5_+_175288631 6.56 ENST00000509837.1
CPLX2
complexin 2
chrX_+_106163626 6.49 ENST00000336803.1
CLDN2
claudin 2
chr8_+_32579271 6.40 ENST00000518084.1
NRG1
neuregulin 1
chr17_-_63557309 4.79 ENST00000580513.1
AXIN2
axin 2
chr5_-_58335281 4.76 ENST00000358923.6
PDE4D
phosphodiesterase 4D, cAMP-specific
chr4_-_139163491 4.48 ENST00000280612.5
SLC7A11
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr8_-_95220775 4.46 ENST00000441892.2
ENST00000521491.1
ENST00000027335.3
CDH17
cadherin 17, LI cadherin (liver-intestine)
chr13_-_67802549 4.29 ENST00000328454.5
ENST00000377865.2
PCDH9
protocadherin 9
chr17_-_63556414 4.17 ENST00000585045.1
AXIN2
axin 2
chr15_-_90294523 4.06 ENST00000300057.4
MESP1
mesoderm posterior 1 homolog (mouse)
chr7_-_27213893 3.99 ENST00000283921.4
HOXA10
homeobox A10
chr2_+_196440692 3.92 ENST00000458054.1
SLC39A10
solute carrier family 39 (zinc transporter), member 10
chr17_-_63557759 3.58 ENST00000307078.5
AXIN2
axin 2
chr10_+_54074033 3.38 ENST00000373970.3
DKK1
dickkopf WNT signaling pathway inhibitor 1
chr10_-_14614122 3.23 ENST00000378465.3
ENST00000452706.2
ENST00000378458.2
FAM107B
family with sequence similarity 107, member B
chr14_-_65409502 3.14 ENST00000389614.5
GPX2
glutathione peroxidase 2 (gastrointestinal)
chr7_-_27219849 3.07 ENST00000396344.4
HOXA10
homeobox A10
chr15_-_82338460 3.03 ENST00000558133.1
ENST00000329713.4
MEX3B
mex-3 RNA binding family member B
chr8_+_32579341 2.97 ENST00000519240.1
ENST00000539990.1
NRG1
neuregulin 1
chrX_-_47004437 2.93 ENST00000276062.8
NDUFB11
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa
chr20_-_656437 2.92 ENST00000488788.2
RP5-850E9.3
Uncharacterized protein
chrX_-_10588595 2.91 ENST00000423614.1
ENST00000317552.4
MID1
midline 1 (Opitz/BBB syndrome)
chr8_+_32579321 2.82 ENST00000522402.1
NRG1
neuregulin 1
chr6_-_24645956 2.78 ENST00000543707.1
KIAA0319
KIAA0319
chr12_+_85673868 2.75 ENST00000316824.3
ALX1
ALX homeobox 1
chr13_-_30160925 2.71 ENST00000450494.1
SLC7A1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr5_+_175815732 2.60 ENST00000274787.2
HIGD2A
HIG1 hypoxia inducible domain family, member 2A
chr1_-_219615984 2.59 ENST00000420762.1
RP11-95P13.1
RP11-95P13.1
chr3_-_149375783 2.55 ENST00000467467.1
ENST00000460517.1
ENST00000360632.3
WWTR1
WW domain containing transcription regulator 1
chr10_-_14614311 2.53 ENST00000479731.1
ENST00000468492.1
FAM107B
family with sequence similarity 107, member B
chr16_+_19222479 2.40 ENST00000568433.1
SYT17
synaptotagmin XVII
chrX_-_47004878 2.39 ENST00000377811.3
NDUFB11
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa
chr2_+_69240511 2.36 ENST00000409349.3
ANTXR1
anthrax toxin receptor 1
chr10_-_14614095 2.34 ENST00000482277.1
ENST00000378462.1
FAM107B
family with sequence similarity 107, member B
chr13_+_24144509 2.34 ENST00000248484.4
TNFRSF19
tumor necrosis factor receptor superfamily, member 19
chr2_+_69240302 2.32 ENST00000303714.4
ANTXR1
anthrax toxin receptor 1
chr12_-_49453557 2.21 ENST00000547610.1
KMT2D
lysine (K)-specific methyltransferase 2D
chr1_-_110933663 2.19 ENST00000369781.4
ENST00000541986.1
ENST00000369779.4
SLC16A4
solute carrier family 16, member 4
chr10_+_7745303 2.09 ENST00000429820.1
ENST00000379587.4
ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chrX_-_10588459 2.04 ENST00000380782.2
MID1
midline 1 (Opitz/BBB syndrome)
chr2_+_69240415 2.02 ENST00000409829.3
ANTXR1
anthrax toxin receptor 1
chr13_+_24144796 1.99 ENST00000403372.2
TNFRSF19
tumor necrosis factor receptor superfamily, member 19
chr17_+_38673270 1.98 ENST00000578280.1
RP5-1028K7.2
RP5-1028K7.2
chr1_-_110933611 1.93 ENST00000472422.2
ENST00000437429.2
SLC16A4
solute carrier family 16, member 4
chr9_-_130712995 1.86 ENST00000373084.4
FAM102A
family with sequence similarity 102, member A
chr9_+_116225999 1.77 ENST00000317613.6
RGS3
regulator of G-protein signaling 3
chr11_+_7597639 1.77 ENST00000533792.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr21_-_35284635 1.77 ENST00000429238.1
AP000304.12
AP000304.12
chr19_-_40791160 1.67 ENST00000358335.5
AKT2
v-akt murine thymoma viral oncogene homolog 2
chr10_+_7745232 1.66 ENST00000358415.4
ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr16_-_73082274 1.64 ENST00000268489.5
ZFHX3
zinc finger homeobox 3
chr19_-_44008863 1.63 ENST00000601646.1
PHLDB3
pleckstrin homology-like domain, family B, member 3
chr10_-_25241499 1.52 ENST00000376378.1
ENST00000376376.3
ENST00000320152.6
PRTFDC1
phosphoribosyl transferase domain containing 1
chr22_+_29279552 1.52 ENST00000544604.2
ZNRF3
zinc and ring finger 3
chr5_+_133450365 1.46 ENST00000342854.5
ENST00000321603.6
ENST00000321584.4
ENST00000378564.1
ENST00000395029.1
TCF7
transcription factor 7 (T-cell specific, HMG-box)
chr10_-_14613968 1.44 ENST00000488576.1
ENST00000472095.1
FAM107B
family with sequence similarity 107, member B
chr3_-_134093738 1.43 ENST00000506107.1
AMOTL2
angiomotin like 2
chr19_-_3061397 1.42 ENST00000586839.1
AES
amino-terminal enhancer of split
chr12_+_52056548 1.39 ENST00000545061.1
ENST00000355133.3
SCN8A
sodium channel, voltage gated, type VIII, alpha subunit
chr12_-_6982442 1.39 ENST00000523102.1
ENST00000524270.1
ENST00000519357.1
SPSB2
splA/ryanodine receptor domain and SOCS box containing 2
chr7_+_150076406 1.39 ENST00000329630.5
ZNF775
zinc finger protein 775
chr17_+_79679299 1.33 ENST00000331531.5
SLC25A10
solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
chr17_+_34848049 1.32 ENST00000588902.1
ENST00000591067.1
ZNHIT3
zinc finger, HIT-type containing 3
chr11_-_62474803 1.24 ENST00000533982.1
ENST00000360796.5
BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr11_-_75921780 1.24 ENST00000529461.1
WNT11
wingless-type MMTV integration site family, member 11
chr6_-_89927151 1.23 ENST00000454853.2
GABRR1
gamma-aminobutyric acid (GABA) A receptor, rho 1
chr1_+_180199393 1.18 ENST00000263726.2
LHX4
LIM homeobox 4
chr22_+_41347363 1.18 ENST00000216225.8
RBX1
ring-box 1, E3 ubiquitin protein ligase
chr13_-_72441315 1.15 ENST00000305425.4
ENST00000313174.7
ENST00000354591.4
DACH1
dachshund homolog 1 (Drosophila)
chr17_+_70026795 1.14 ENST00000472655.2
ENST00000538810.1
RP11-84E24.3
long intergenic non-protein coding RNA 1152
chr21_+_30672433 1.11 ENST00000451655.1
BACH1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr14_-_81425828 1.11 ENST00000555529.1
ENST00000556042.1
ENST00000556981.1
CEP128
centrosomal protein 128kDa
chr12_+_6982725 1.10 ENST00000433346.1
LRRC23
leucine rich repeat containing 23
chr15_+_101402041 1.09 ENST00000558475.1
ENST00000558641.1
ENST00000559673.1
RP11-66B24.1
RP11-66B24.1
chr17_+_68100989 1.07 ENST00000585558.1
ENST00000392670.1
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chr7_-_148581251 1.05 ENST00000478654.1
ENST00000460911.1
ENST00000350995.2
EZH2
enhancer of zeste homolog 2 (Drosophila)
chr14_+_23235886 1.03 ENST00000604262.1
ENST00000431881.2
ENST00000412791.1
ENST00000358043.5
OXA1L
oxidase (cytochrome c) assembly 1-like
chr13_-_36429763 1.02 ENST00000379893.1
DCLK1
doublecortin-like kinase 1
chr4_+_95972822 1.02 ENST00000509540.1
ENST00000440890.2
BMPR1B
bone morphogenetic protein receptor, type IB
chr3_-_45957534 1.00 ENST00000536047.1
LZTFL1
leucine zipper transcription factor-like 1
chr22_+_31742875 0.98 ENST00000504184.2
AC005003.1
CDNA FLJ20464 fis, clone KAT06158; HCG1777549; Uncharacterized protein
chr12_+_9066472 0.98 ENST00000538657.1
PHC1
polyhomeotic homolog 1 (Drosophila)
chr1_-_231005310 0.97 ENST00000470540.1
C1orf198
chromosome 1 open reading frame 198
chr12_+_9067123 0.97 ENST00000543824.1
PHC1
polyhomeotic homolog 1 (Drosophila)
chr11_-_76155618 0.96 ENST00000530759.1
RP11-111M22.3
RP11-111M22.3
chr3_-_45957088 0.96 ENST00000539217.1
LZTFL1
leucine zipper transcription factor-like 1
chr17_-_56065540 0.96 ENST00000583932.1
VEZF1
vascular endothelial zinc finger 1
chr2_+_233385173 0.95 ENST00000449534.2
PRSS56
protease, serine, 56
chr9_-_77502636 0.95 ENST00000449912.2
TRPM6
transient receptor potential cation channel, subfamily M, member 6
chr15_+_81293254 0.95 ENST00000267984.2
MESDC1
mesoderm development candidate 1
chr10_-_75351088 0.95 ENST00000451492.1
ENST00000413442.1
USP54
ubiquitin specific peptidase 54
chr1_-_161993616 0.93 ENST00000294794.3
OLFML2B
olfactomedin-like 2B
chr12_-_49582978 0.89 ENST00000301071.7
TUBA1A
tubulin, alpha 1a
chr6_+_64281906 0.89 ENST00000370651.3
PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr7_-_148581360 0.88 ENST00000320356.2
ENST00000541220.1
ENST00000483967.1
ENST00000536783.1
EZH2
enhancer of zeste homolog 2 (Drosophila)
chr5_+_140235469 0.88 ENST00000506939.2
ENST00000307360.5
PCDHA10
protocadherin alpha 10
chr19_-_40791211 0.88 ENST00000579047.1
AKT2
v-akt murine thymoma viral oncogene homolog 2
chr2_+_33701286 0.87 ENST00000403687.3
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr22_-_33968239 0.87 ENST00000452586.2
ENST00000421768.1
LARGE
like-glycosyltransferase
chr10_+_115312766 0.84 ENST00000351270.3
HABP2
hyaluronan binding protein 2
chr11_+_65408273 0.82 ENST00000394227.3
SIPA1
signal-induced proliferation-associated 1
chr17_+_68101117 0.81 ENST00000587698.1
ENST00000587892.1
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chrX_-_153599578 0.81 ENST00000360319.4
ENST00000344736.4
FLNA
filamin A, alpha
chr7_-_25702669 0.80 ENST00000446840.1
AC003090.1
AC003090.1
chr17_+_80416050 0.77 ENST00000579198.1
ENST00000390006.4
ENST00000580296.1
NARF
nuclear prelamin A recognition factor
chr5_+_54455946 0.77 ENST00000503787.1
ENST00000296734.6
ENST00000515370.1
GPX8
glutathione peroxidase 8 (putative)
chr17_+_59529743 0.76 ENST00000589003.1
ENST00000393853.4
TBX4
T-box 4
chr4_+_183065793 0.76 ENST00000512480.1
TENM3
teneurin transmembrane protein 3
chr17_+_80818231 0.76 ENST00000576996.1
TBCD
tubulin folding cofactor D
chr10_-_87551311 0.76 ENST00000536331.1
GRID1
glutamate receptor, ionotropic, delta 1
chr12_-_130529501 0.75 ENST00000561864.1
ENST00000567788.1
RP11-474D1.4
RP11-474D1.3
RP11-474D1.4
RP11-474D1.3
chr4_-_123542224 0.75 ENST00000264497.3
IL21
interleukin 21
chr19_-_40791302 0.75 ENST00000392038.2
ENST00000578123.1
AKT2
v-akt murine thymoma viral oncogene homolog 2
chr2_+_204801471 0.74 ENST00000316386.6
ENST00000435193.1
ICOS
inducible T-cell co-stimulator
chr2_-_97536490 0.73 ENST00000449330.1
SEMA4C
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
chr1_-_54304212 0.72 ENST00000540001.1
NDC1
NDC1 transmembrane nucleoporin
chr2_-_55646957 0.72 ENST00000263630.8
CCDC88A
coiled-coil domain containing 88A
chr8_-_16859690 0.71 ENST00000180166.5
FGF20
fibroblast growth factor 20
chr2_-_55647057 0.70 ENST00000436346.1
CCDC88A
coiled-coil domain containing 88A
chr12_+_122326630 0.70 ENST00000541212.1
ENST00000340175.5
PSMD9
proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
chr11_-_76155700 0.69 ENST00000572035.1
RP11-111M22.3
RP11-111M22.3
chr1_+_207039154 0.69 ENST00000367096.3
ENST00000391930.2
IL20
interleukin 20
chr12_+_54694979 0.66 ENST00000552848.1
COPZ1
coatomer protein complex, subunit zeta 1
chr2_-_9771075 0.65 ENST00000446619.1
ENST00000238081.3
YWHAQ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
chr20_-_17511962 0.65 ENST00000377873.3
BFSP1
beaded filament structural protein 1, filensin
chr17_-_47308128 0.64 ENST00000413580.1
ENST00000511066.1
PHOSPHO1
phosphatase, orphan 1
chr9_-_15510287 0.63 ENST00000397519.2
PSIP1
PC4 and SFRS1 interacting protein 1
chr4_-_85419603 0.62 ENST00000295886.4
NKX6-1
NK6 homeobox 1
chr14_+_93118813 0.62 ENST00000556418.1
RIN3
Ras and Rab interactor 3
chr5_+_170846640 0.60 ENST00000274625.5
FGF18
fibroblast growth factor 18
chr2_-_71357344 0.59 ENST00000494660.2
ENST00000244217.5
ENST00000486135.1
MCEE
methylmalonyl CoA epimerase
chr1_-_201096312 0.59 ENST00000449188.2
ASCL5
achaete-scute family bHLH transcription factor 5
chr6_+_35704855 0.59 ENST00000288065.2
ENST00000373866.3
ARMC12
armadillo repeat containing 12
chr12_-_49582593 0.58 ENST00000295766.5
TUBA1A
tubulin, alpha 1a
chr1_-_65533390 0.57 ENST00000448344.1
RP4-535B20.1
RP4-535B20.1
chr19_-_59030921 0.56 ENST00000354590.3
ENST00000596739.1
ZBTB45
zinc finger and BTB domain containing 45
chrX_+_54835493 0.55 ENST00000396224.1
MAGED2
melanoma antigen family D, 2
chr7_+_27282319 0.53 ENST00000222761.3
EVX1
even-skipped homeobox 1
chrX_-_110655306 0.52 ENST00000371993.2
DCX
doublecortin
chr8_+_29952914 0.51 ENST00000321250.8
ENST00000518001.1
ENST00000520682.1
ENST00000442880.2
ENST00000523116.1
LEPROTL1
leptin receptor overlapping transcript-like 1
chrX_-_100183894 0.50 ENST00000328526.5
ENST00000372956.2
XKRX
XK, Kell blood group complex subunit-related, X-linked
chr5_-_175815565 0.50 ENST00000509257.1
ENST00000507413.1
ENST00000510123.1
NOP16
NOP16 nucleolar protein
chr3_-_134093395 0.50 ENST00000249883.5
AMOTL2
angiomotin like 2
chr19_-_59031118 0.49 ENST00000600990.1
ZBTB45
zinc finger and BTB domain containing 45
chr3_-_155011483 0.49 ENST00000489090.1
RP11-451G4.2
RP11-451G4.2
chr14_+_59100774 0.48 ENST00000556859.1
ENST00000421793.1
DACT1
dishevelled-binding antagonist of beta-catenin 1
chr10_+_115312825 0.48 ENST00000537906.1
ENST00000541666.1
HABP2
hyaluronan binding protein 2
chr10_+_105005644 0.48 ENST00000441178.2
RP11-332O19.5
ribulose-5-phosphate-3-epimerase-like 1
chr17_-_73389737 0.47 ENST00000392563.1
GRB2
growth factor receptor-bound protein 2
chrX_-_111923145 0.47 ENST00000371968.3
ENST00000536453.1
LHFPL1
lipoma HMGIC fusion partner-like 1
chr9_+_139221880 0.47 ENST00000392945.3
ENST00000440944.1
GPSM1
G-protein signaling modulator 1
chr1_-_205419053 0.46 ENST00000367154.1
LEMD1
LEM domain containing 1
chr5_-_160973649 0.46 ENST00000393959.1
ENST00000517547.1
GABRB2
gamma-aminobutyric acid (GABA) A receptor, beta 2
chr15_+_90744745 0.46 ENST00000558051.1
SEMA4B
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr6_-_32083106 0.45 ENST00000442721.1
TNXB
tenascin XB
chr3_-_33686743 0.43 ENST00000333778.6
ENST00000539981.1
CLASP2
cytoplasmic linker associated protein 2
chr4_-_120243545 0.42 ENST00000274024.3
FABP2
fatty acid binding protein 2, intestinal
chr2_+_177028805 0.42 ENST00000249440.3
HOXD3
homeobox D3
chr14_-_53258314 0.41 ENST00000216410.3
ENST00000557604.1
GNPNAT1
glucosamine-phosphate N-acetyltransferase 1
chr12_-_23737534 0.40 ENST00000396007.2
SOX5
SRY (sex determining region Y)-box 5
chr1_-_11907829 0.40 ENST00000376480.3
NPPA
natriuretic peptide A
chr15_+_96897466 0.40 ENST00000558382.1
ENST00000558499.1
RP11-522B15.3
RP11-522B15.3
chr5_-_135290651 0.39 ENST00000522943.1
ENST00000514447.2
LECT2
leukocyte cell-derived chemotaxin 2
chrX_+_123097014 0.38 ENST00000394478.1
STAG2
stromal antigen 2
chr18_-_24445729 0.37 ENST00000383168.4
AQP4
aquaporin 4
chr3_+_141106643 0.37 ENST00000514251.1
ZBTB38
zinc finger and BTB domain containing 38
chr12_+_122326662 0.36 ENST00000261817.2
ENST00000538613.1
ENST00000542602.1
PSMD9
proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
chr20_+_57875658 0.35 ENST00000371025.3
EDN3
endothelin 3
chr7_+_137761199 0.35 ENST00000411726.2
AKR1D1
aldo-keto reductase family 1, member D1
chr14_-_65785502 0.34 ENST00000553754.1
CTD-2509G16.5
CTD-2509G16.5
chr6_+_155537771 0.34 ENST00000275246.7
TIAM2
T-cell lymphoma invasion and metastasis 2
chr5_-_153857819 0.34 ENST00000231121.2
HAND1
heart and neural crest derivatives expressed 1
chr15_-_89764929 0.33 ENST00000268125.5
RLBP1
retinaldehyde binding protein 1
chr3_-_33686925 0.32 ENST00000485378.2
ENST00000313350.6
ENST00000487200.1
CLASP2
cytoplasmic linker associated protein 2
chr10_+_114133773 0.32 ENST00000354655.4
ACSL5
acyl-CoA synthetase long-chain family member 5
chr12_+_31477250 0.31 ENST00000313737.4
AC024940.1
AC024940.1
chr12_-_54694807 0.29 ENST00000435572.2
NFE2
nuclear factor, erythroid 2
chr10_+_71561630 0.29 ENST00000398974.3
ENST00000398971.3
ENST00000398968.3
ENST00000398966.3
ENST00000398964.3
ENST00000398969.3
ENST00000356340.3
ENST00000398972.3
ENST00000398973.3
COL13A1
collagen, type XIII, alpha 1
chr7_-_75452673 0.28 ENST00000416943.1
CCL24
chemokine (C-C motif) ligand 24
chr7_+_110731062 0.28 ENST00000308478.5
ENST00000451085.1
ENST00000422987.3
ENST00000421101.1
LRRN3
leucine rich repeat neuronal 3
chr16_+_50582222 0.27 ENST00000268459.3
NKD1
naked cuticle homolog 1 (Drosophila)
chr17_+_80416482 0.26 ENST00000309794.11
ENST00000345415.7
ENST00000457415.3
ENST00000584411.1
ENST00000412079.2
ENST00000577432.1
NARF
nuclear prelamin A recognition factor
chrX_-_63005405 0.25 ENST00000374878.1
ENST00000437457.2
ARHGEF9
Cdc42 guanine nucleotide exchange factor (GEF) 9
chr2_+_171571827 0.25 ENST00000375281.3
SP5
Sp5 transcription factor
chr12_-_49582837 0.24 ENST00000547939.1
ENST00000546918.1
ENST00000552924.1
TUBA1A
tubulin, alpha 1a
chr6_+_152130240 0.24 ENST00000427531.2
ESR1
estrogen receptor 1
chr3_+_259218 0.23 ENST00000449294.2
CHL1
cell adhesion molecule L1-like
chr1_+_162351503 0.23 ENST00000458626.2
C1orf226
chromosome 1 open reading frame 226
chr1_+_223101757 0.23 ENST00000284476.6
DISP1
dispatched homolog 1 (Drosophila)
chr1_+_215179188 0.22 ENST00000391895.2
KCNK2
potassium channel, subfamily K, member 2
chr1_+_200860122 0.22 ENST00000532631.1
ENST00000451872.2
C1orf106
chromosome 1 open reading frame 106
chr2_+_201936707 0.22 ENST00000433898.1
ENST00000454214.1
NDUFB3
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa
chr2_-_9770706 0.21 ENST00000381844.4
YWHAQ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
chr18_+_19668021 0.21 ENST00000579830.1
RP11-595B24.2
Uncharacterized protein
chr5_+_102200948 0.20 ENST00000511477.1
ENST00000506006.1
ENST00000509832.1
PAM
peptidylglycine alpha-amidating monooxygenase
chr17_+_80416609 0.20 ENST00000577410.1
NARF
nuclear prelamin A recognition factor

Network of associatons between targets according to the STRING database.

First level regulatory network of TCF7L2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
4.2 12.5 GO:0061181 regulation of chondrocyte development(GO:0061181)
2.8 8.5 GO:0050787 antibiotic metabolic process(GO:0016999) detoxification of mercury ion(GO:0050787)
2.5 7.4 GO:0090381 regulation of heart induction(GO:0090381) regulation of heart induction by canonical Wnt signaling pathway(GO:0100012)
2.2 6.7 GO:1901202 negative regulation of extracellular matrix assembly(GO:1901202)
1.4 12.2 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.9 4.5 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.8 3.9 GO:1903615 regulation of protein tyrosine phosphatase activity(GO:1903613) positive regulation of protein tyrosine phosphatase activity(GO:1903615)
0.7 2.0 GO:1903568 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.6 1.9 GO:0036333 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.5 1.5 GO:1901069 guanosine-containing compound catabolic process(GO:1901069)
0.5 4.8 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.5 3.3 GO:0071486 cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.4 1.3 GO:0071423 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) malate transmembrane transport(GO:0071423) oxaloacetate(2-) transmembrane transport(GO:1902356)
0.4 1.6 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.4 1.2 GO:0021526 medial motor column neuron differentiation(GO:0021526)
0.4 2.2 GO:0001555 oocyte growth(GO:0001555)
0.4 7.6 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.4 1.4 GO:1903566 regulation of protein localization to cilium(GO:1903564) positive regulation of protein localization to cilium(GO:1903566)
0.3 2.7 GO:1903826 arginine transmembrane transport(GO:1903826)
0.3 1.2 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
0.3 1.5 GO:2000051 Wnt receptor catabolic process(GO:0038018) negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.3 4.9 GO:0035372 protein localization to microtubule(GO:0035372)
0.3 1.2 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.3 1.9 GO:0048619 embryonic hindgut morphogenesis(GO:0048619)
0.3 0.8 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.2 6.6 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.2 1.1 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.2 1.0 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.2 6.5 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.2 7.3 GO:0060065 uterus development(GO:0060065)
0.2 0.8 GO:0042631 cellular response to water deprivation(GO:0042631)
0.2 0.8 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.1 1.0 GO:0048165 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.1 4.5 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.1 0.4 GO:0070632 spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
0.1 2.5 GO:0072257 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.1 0.6 GO:0014826 vein smooth muscle contraction(GO:0014826)
0.1 1.2 GO:0010265 SCF complex assembly(GO:0010265)
0.1 0.7 GO:1904338 regulation of dopaminergic neuron differentiation(GO:1904338)
0.1 2.7 GO:0001502 cartilage condensation(GO:0001502)
0.1 1.4 GO:2000210 positive regulation of anoikis(GO:2000210)
0.1 0.6 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.1 0.5 GO:0030573 bile acid catabolic process(GO:0030573)
0.1 0.9 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.1 0.6 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.1 0.4 GO:1902304 positive regulation of potassium ion export(GO:1902304)
0.1 0.6 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.1 0.8 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.1 0.1 GO:0003192 mitral valve formation(GO:0003192)
0.1 0.3 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.1 0.3 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.1 5.1 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 0.5 GO:0006041 glucosamine metabolic process(GO:0006041)
0.1 0.7 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.1 2.8 GO:2000171 negative regulation of dendrite development(GO:2000171)
0.0 2.4 GO:1903861 regulation of dendrite extension(GO:1903859) positive regulation of dendrite extension(GO:1903861)
0.0 0.3 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.0 0.7 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091) negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.7 GO:0002517 T cell tolerance induction(GO:0002517)
0.0 0.5 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.2 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
0.0 0.2 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.0 0.5 GO:0035630 bone mineralization involved in bone maturation(GO:0035630)
0.0 1.7 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.3 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.0 0.4 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.4 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 1.2 GO:0034389 lipid particle organization(GO:0034389)
0.0 1.8 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 2.0 GO:0035329 hippo signaling(GO:0035329)
0.0 0.8 GO:0097264 self proteolysis(GO:0097264)
0.0 0.1 GO:0003257 positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation(GO:0003257) positive regulation of transcription from RNA polymerase II promoter involved in heart development(GO:1901228)
0.0 0.7 GO:0035635 entry of bacterium into host cell(GO:0035635)
0.0 2.3 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 11.9 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.0 0.4 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 1.8 GO:0010107 potassium ion import(GO:0010107)
0.0 0.4 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 0.1 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.0 1.9 GO:0016574 histone ubiquitination(GO:0016574)
0.0 0.1 GO:2000015 regulation of determination of dorsal identity(GO:2000015)
0.0 1.0 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 3.4 GO:0098869 cellular oxidant detoxification(GO:0098869)
0.0 0.3 GO:0060539 diaphragm development(GO:0060539)
0.0 0.7 GO:0045618 positive regulation of keratinocyte differentiation(GO:0045618)
0.0 0.7 GO:0021535 cell migration in hindbrain(GO:0021535)
0.0 0.3 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.5 GO:0006833 water transport(GO:0006833)
0.0 0.0 GO:0032730 positive regulation of interleukin-1 alpha production(GO:0032730)
0.0 4.1 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 0.2 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.0 0.9 GO:1900740 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.0 0.1 GO:0000270 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.8 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 0.2 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.4 GO:0035640 exploration behavior(GO:0035640)
0.0 1.4 GO:0007422 peripheral nervous system development(GO:0007422)
0.0 0.2 GO:0035878 nail development(GO:0035878)
0.0 0.5 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.4 GO:0019433 triglyceride catabolic process(GO:0019433)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 8.5 GO:0046581 intercellular canaliculus(GO:0046581)
0.7 6.6 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.5 11.8 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.4 1.2 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
0.2 12.2 GO:0030673 axolemma(GO:0030673)
0.2 0.8 GO:0031523 Myb complex(GO:0031523)
0.1 2.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.1 0.4 GO:0070762 nuclear pore transmembrane ring(GO:0070762)
0.1 1.2 GO:0005638 lamin filament(GO:0005638)
0.1 5.6 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 0.7 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.1 0.4 GO:0030936 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.1 1.9 GO:0035102 PRC1 complex(GO:0035102)
0.1 1.9 GO:0045120 pronucleus(GO:0045120)
0.1 7.4 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 8.7 GO:0070469 respiratory chain(GO:0070469)
0.1 1.0 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.1 0.5 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.1 4.8 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 1.4 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 0.6 GO:0005882 intermediate filament(GO:0005882)
0.1 0.2 GO:0035841 new growing cell tip(GO:0035841)
0.1 1.7 GO:1902711 GABA-A receptor complex(GO:1902711)
0.1 1.1 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.7 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 4.5 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 1.5 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 3.5 GO:0044291 cell-cell contact zone(GO:0044291)
0.0 7.1 GO:0005923 bicellular tight junction(GO:0005923)
0.0 0.9 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.9 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.4 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.2 GO:0044305 calyx of Held(GO:0044305)
0.0 5.7 GO:0031901 early endosome membrane(GO:0031901)
0.0 11.6 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.8 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 3.2 GO:0032587 ruffle membrane(GO:0032587)
0.0 4.0 GO:0072562 blood microparticle(GO:0072562)
0.0 7.0 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 3.0 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 1.0 GO:0005783 endoplasmic reticulum(GO:0005783)
0.0 2.5 GO:0005814 centriole(GO:0005814)
0.0 0.4 GO:0042629 mast cell granule(GO:0042629)
0.0 0.1 GO:0045179 apical cortex(GO:0045179)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 7.6 GO:0008112 nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
1.5 4.5 GO:0005427 proton-dependent oligopeptide secondary active transmembrane transporter activity(GO:0005427) secondary active oligopeptide transmembrane transporter activity(GO:0015322)
1.0 12.2 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.9 4.5 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.4 12.5 GO:0070411 I-SMAD binding(GO:0070411)
0.4 8.5 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.4 1.3 GO:0015117 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131)
0.3 7.6 GO:0050786 RAGE receptor binding(GO:0050786)
0.3 2.7 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.2 0.7 GO:0045518 interleukin-22 receptor binding(GO:0045518)
0.2 4.8 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.2 1.9 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.2 3.4 GO:0048019 receptor antagonist activity(GO:0048019)
0.1 0.6 GO:0097100 supercoiled DNA binding(GO:0097100)
0.1 3.9 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 0.6 GO:0031708 endothelin B receptor binding(GO:0031708)
0.1 0.6 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1 1.2 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.1 6.6 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 0.8 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.1 0.7 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.1 1.0 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 4.3 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 0.5 GO:0047787 delta4-3-oxosteroid 5beta-reductase activity(GO:0047787)
0.1 3.9 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 1.9 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 2.2 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1 0.3 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.1 0.3 GO:0005502 11-cis retinal binding(GO:0005502)
0.1 1.4 GO:0043422 protein kinase B binding(GO:0043422)
0.1 0.5 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.0 4.1 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 6.7 GO:0005518 collagen binding(GO:0005518)
0.0 0.5 GO:0070097 delta-catenin binding(GO:0070097)
0.0 1.4 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.2 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.0 1.2 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.7 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.7 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.0 1.2 GO:0005521 lamin binding(GO:0005521)
0.0 5.8 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 4.5 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 0.1 GO:0004803 transposase activity(GO:0004803)
0.0 0.7 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.9 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 1.2 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.5 GO:0015250 water channel activity(GO:0015250)
0.0 0.6 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 1.3 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 1.3 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 2.4 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.2 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 1.1 GO:0005109 frizzled binding(GO:0005109)
0.0 0.8 GO:0005234 extracellular-glutamate-gated ion channel activity(GO:0005234)
0.0 3.1 GO:0035326 enhancer binding(GO:0035326)
0.0 1.5 GO:0016763 transferase activity, transferring pentosyl groups(GO:0016763)
0.0 0.1 GO:0098821 BMP receptor activity(GO:0098821)
0.0 0.6 GO:0016854 racemase and epimerase activity(GO:0016854)
0.0 0.9 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.2 GO:0015197 peptide transporter activity(GO:0015197)
0.0 0.4 GO:0005184 neuropeptide hormone activity(GO:0005184) peptide hormone receptor binding(GO:0051428)
0.0 0.5 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 1.2 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.4 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.8 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.1 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.9 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.2 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.3 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.5 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 1.0 GO:0043022 ribosome binding(GO:0043022)
0.0 0.4 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.0 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 12.2 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.3 11.3 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.2 6.7 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.2 7.1 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 7.3 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 4.0 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.2 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.7 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 1.7 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 1.8 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.9 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.8 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.9 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.5 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 4.8 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.4 PID AP1 PATHWAY AP-1 transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 15.5 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.2 8.5 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.1 5.9 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 3.9 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 4.6 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 7.2 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 1.3 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.1 0.6 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1 4.8 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 2.5 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 1.9 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 6.1 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.0 0.7 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 1.2 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 1.3 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 1.9 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.7 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.5 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.5 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.6 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.5 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 1.0 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.6 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.5 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.7 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.2 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 1.1 REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.0 0.6 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.9 REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)