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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for TFAP2B

Z-value: 2.66

Motif logo

Transcription factors associated with TFAP2B

Gene Symbol Gene ID Gene Info
ENSG00000008196.8 transcription factor AP-2 beta

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TFAP2Bhg19_v2_chr6_+_50786414_50786439-0.272.4e-01Click!

Activity profile of TFAP2B motif

Sorted Z-values of TFAP2B motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_52914155 18.68 ENST00000549420.1
ENST00000551275.1
ENST00000546577.1
keratin 5
chr17_-_39677971 11.82 ENST00000393976.2
keratin 15
chr13_-_107187462 9.92 ENST00000245323.4
ephrin-B2
chr1_-_153588334 9.85 ENST00000476873.1
S100 calcium binding protein A14
chr16_+_68679193 9.79 ENST00000581171.1
cadherin 3, type 1, P-cadherin (placental)
chr16_+_68678892 9.77 ENST00000429102.2
cadherin 3, type 1, P-cadherin (placental)
chr21_-_28217721 9.30 ENST00000284984.3
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr1_+_152881014 9.25 ENST00000368764.3
ENST00000392667.2
involucrin
chr1_+_32042131 8.93 ENST00000271064.7
ENST00000537531.1
tubulointerstitial nephritis antigen-like 1
chr1_+_32042105 8.66 ENST00000457433.2
ENST00000441210.2
tubulointerstitial nephritis antigen-like 1
chr6_+_54711533 7.62 ENST00000306858.7
family with sequence similarity 83, member B
chr14_+_94640633 6.98 ENST00000304338.3
protein phosphatase 4, regulatory subunit 4
chr1_+_209602771 6.88 ENST00000440276.1
MIR205 host gene (non-protein coding)
chr8_-_143867946 6.75 ENST00000301263.4
lymphocyte antigen 6 complex, locus D
chr1_+_2398876 6.25 ENST00000449969.1
phospholipase C, eta 2
chr12_-_89746173 6.16 ENST00000308385.6
dual specificity phosphatase 6
chr9_-_21974820 6.06 ENST00000579122.1
ENST00000498124.1
cyclin-dependent kinase inhibitor 2A
chr9_-_21975088 6.00 ENST00000304494.5
cyclin-dependent kinase inhibitor 2A
chr2_+_208104351 5.98 ENST00000440326.1
AC007879.7
chr1_+_160370344 5.80 ENST00000368061.2
VANGL planar cell polarity protein 2
chr19_-_11689752 5.64 ENST00000592659.1
ENST00000592828.1
ENST00000218758.5
ENST00000412435.2
acid phosphatase 5, tartrate resistant
chr10_+_71078595 5.62 ENST00000359426.6
hexokinase 1
chr1_+_209602609 5.62 ENST00000458250.1
MIR205 host gene (non-protein coding)
chr15_+_101420028 5.55 ENST00000557963.1
ENST00000346623.6
aldehyde dehydrogenase 1 family, member A3
chr7_-_143105941 5.54 ENST00000275815.3
EPH receptor A1
chr12_-_57634475 5.49 ENST00000393825.1
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
chr16_-_68269971 5.43 ENST00000565858.1
epithelial splicing regulatory protein 2
chr2_+_208104497 5.39 ENST00000430494.1
AC007879.7
chr19_-_19739007 5.34 ENST00000586703.1
ENST00000591042.1
ENST00000407877.3
lysophosphatidic acid receptor 2
chr17_-_5487768 5.29 ENST00000269280.4
ENST00000345221.3
ENST00000262467.5
NLR family, pyrin domain containing 1
chr12_-_15114603 5.06 ENST00000228945.4
Rho GDP dissociation inhibitor (GDI) beta
chr6_+_43112037 5.06 ENST00000473339.1
protein tyrosine kinase 7
chr3_-_52090461 4.99 ENST00000296483.6
ENST00000495880.1
dual specificity phosphatase 7
chr16_+_30907927 4.96 ENST00000279804.2
ENST00000395019.3
cardiotrophin 1
chr18_+_33877654 4.92 ENST00000257209.4
ENST00000445677.1
ENST00000590592.1
ENST00000359247.4
formin homology 2 domain containing 3
chr5_+_148521381 4.88 ENST00000504238.1
actin binding LIM protein family, member 3
chr1_-_27339317 4.80 ENST00000289166.5
family with sequence similarity 46, member B
chr12_-_123380610 4.57 ENST00000535765.1
vacuolar protein sorting 37 homolog B (S. cerevisiae)
chr11_+_131781290 4.36 ENST00000425719.2
ENST00000374784.1
neurotrimin
chr3_+_100211412 4.35 ENST00000323523.4
ENST00000403410.1
ENST00000449609.1
transmembrane protein 45A
chr19_-_37341160 4.21 ENST00000528994.1
zinc finger protein 790
chr20_+_62327996 4.07 ENST00000369996.1
tumor necrosis factor receptor superfamily, member 6b, decoy
chr21_-_45078019 4.00 ENST00000542962.1
heat shock transcription factor 2 binding protein
chr3_-_48470838 3.97 ENST00000358459.4
ENST00000358536.4
plexin B1
chr11_-_61348576 3.93 ENST00000263846.4
synaptotagmin VII
chr15_+_78556809 3.93 ENST00000343789.3
ENST00000394852.3
DnaJ (Hsp40) homolog, subfamily A, member 4
chr17_+_42429493 3.90 ENST00000586242.1
granulin
chr17_+_7758374 3.78 ENST00000301599.6
ENST00000574668.1
transmembrane protein 88
chr1_-_6321035 3.70 ENST00000377893.2
G protein-coupled receptor 153
chr5_+_148521136 3.69 ENST00000506113.1
actin binding LIM protein family, member 3
chr4_-_83719983 3.61 ENST00000319540.4
stearoyl-CoA desaturase 5
chr11_-_7695437 3.60 ENST00000533558.1
ENST00000527542.1
ENST00000531096.1
cytochrome b5 reductase 2
chr12_-_15114492 3.58 ENST00000541546.1
Rho GDP dissociation inhibitor (GDI) beta
chr17_-_4463856 3.57 ENST00000574584.1
ENST00000381550.3
ENST00000301395.3
gamma-glutamyltransferase 6
chr19_+_35645817 3.57 ENST00000423817.3
FXYD domain containing ion transport regulator 5
chr12_-_15114191 3.54 ENST00000541380.1
Rho GDP dissociation inhibitor (GDI) beta
chr1_+_40506392 3.54 ENST00000414893.1
ENST00000414281.1
ENST00000420216.1
ENST00000372792.2
ENST00000372798.1
ENST00000340450.3
ENST00000372805.3
ENST00000435719.1
ENST00000427843.1
ENST00000417287.1
ENST00000424977.1
ENST00000446031.1
CAP, adenylate cyclase-associated protein 1 (yeast)
chr19_+_35645618 3.50 ENST00000392218.2
ENST00000543307.1
ENST00000392219.2
ENST00000541435.2
ENST00000590686.1
ENST00000342879.3
ENST00000588699.1
FXYD domain containing ion transport regulator 5
chr5_+_148521046 3.49 ENST00000326685.7
ENST00000356541.3
ENST00000309868.7
actin binding LIM protein family, member 3
chr1_-_9189229 3.47 ENST00000377411.4
G protein-coupled receptor 157
chr14_+_72052983 3.42 ENST00000358550.2
signal-induced proliferation-associated 1 like 1
chr1_-_27286897 3.41 ENST00000320567.5
chromosome 1 open reading frame 172
chr7_+_75932863 3.34 ENST00000429938.1
heat shock 27kDa protein 1
chr2_-_220408430 3.30 ENST00000243776.6
chondroitin polymerizing factor
chr1_-_31902614 3.29 ENST00000596131.1
HCG1787699; Uncharacterized protein
chr17_+_7255208 3.27 ENST00000333751.3
potassium channel tetramerization domain containing 11
chr9_+_112542591 3.23 ENST00000483909.1
ENST00000314527.4
ENST00000413420.1
ENST00000302798.7
ENST00000555236.1
ENST00000510514.5
paralemmin 2
PALM2-AKAP2 readthrough
A kinase (PRKA) anchor protein 2
chr11_-_7694684 3.20 ENST00000524790.1
ENST00000299497.9
ENST00000299498.6
cytochrome b5 reductase 2
chr19_-_19739321 3.19 ENST00000588461.1
lysophosphatidic acid receptor 2
chr1_+_40506255 3.18 ENST00000421589.1
CAP, adenylate cyclase-associated protein 1 (yeast)
chr14_+_94640671 3.16 ENST00000328839.3
protein phosphatase 4, regulatory subunit 4
chr14_-_91720224 3.10 ENST00000238699.3
ENST00000531499.2
G protein-coupled receptor 68
chr15_+_78556428 3.10 ENST00000394855.3
ENST00000489435.2
DnaJ (Hsp40) homolog, subfamily A, member 4
chr3_+_42544084 3.01 ENST00000543411.1
ENST00000438259.2
ENST00000439731.1
ENST00000325123.4
vasoactive intestinal peptide receptor 1
chr16_+_2867164 2.98 ENST00000455114.1
ENST00000450020.3
protease, serine, 21 (testisin)
chr15_+_96873921 2.97 ENST00000394166.3
nuclear receptor subfamily 2, group F, member 2
chr11_-_7694974 2.96 ENST00000436351.2
cytochrome b5 reductase 2
chr6_-_35464727 2.95 ENST00000402886.3
TEA domain family member 3
chr6_-_35464817 2.94 ENST00000338863.7
TEA domain family member 3
chr12_-_89746264 2.94 ENST00000548755.1
dual specificity phosphatase 6
chr12_-_48152428 2.90 ENST00000449771.2
ENST00000395358.3
Rap guanine nucleotide exchange factor (GEF) 3
chr5_+_148521454 2.90 ENST00000508983.1
actin binding LIM protein family, member 3
chr7_-_27169801 2.89 ENST00000511914.1
homeobox A4
chr16_+_2867228 2.87 ENST00000005995.3
ENST00000574813.1
protease, serine, 21 (testisin)
chr1_-_21503337 2.86 ENST00000400422.1
ENST00000602326.1
ENST00000411888.1
ENST00000438975.1
eukaryotic translation initiation factor 4 gamma, 3
chr10_-_5638048 2.86 ENST00000478294.1
RP13-463N16.6
chr2_-_222436988 2.85 ENST00000409854.1
ENST00000281821.2
ENST00000392071.4
ENST00000443796.1
EPH receptor A4
chr16_+_22825475 2.84 ENST00000261374.3
heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr3_+_10857885 2.84 ENST00000254488.2
ENST00000454147.1
solute carrier family 6 (neurotransmitter transporter), member 11
chr10_+_135340859 2.84 ENST00000252945.3
ENST00000421586.1
ENST00000418356.1
cytochrome P450, family 2, subfamily E, polypeptide 1
chr3_-_183145873 2.80 ENST00000447025.2
ENST00000414362.2
ENST00000328913.3
MCF.2 cell line derived transforming sequence-like 2
chr14_+_65171099 2.79 ENST00000247226.7
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr19_+_45971246 2.76 ENST00000585836.1
ENST00000417353.2
ENST00000353609.3
ENST00000591858.1
ENST00000443841.2
ENST00000590335.1
FBJ murine osteosarcoma viral oncogene homolog B
chr6_-_35888824 2.70 ENST00000361690.3
ENST00000512445.1
SRSF protein kinase 1
chr16_-_75498450 2.66 ENST00000566594.1
Uncharacterized protein
chr1_+_33207381 2.66 ENST00000401073.2
KIAA1522
chr3_-_49459865 2.64 ENST00000427987.1
aminomethyltransferase
chr9_+_124030338 2.61 ENST00000449773.1
ENST00000432226.1
ENST00000436847.1
ENST00000394353.2
ENST00000449733.1
ENST00000412819.1
ENST00000341272.2
ENST00000373808.2
gelsolin
chr11_-_61348292 2.60 ENST00000539008.1
ENST00000540677.1
ENST00000542836.1
ENST00000542670.1
ENST00000535826.1
ENST00000545053.1
synaptotagmin VII
chr6_-_30654977 2.58 ENST00000399199.3
protein phosphatase 1, regulatory subunit 18
chr10_+_11047259 2.57 ENST00000379261.4
ENST00000416382.2
CUGBP, Elav-like family member 2
chr4_-_1723040 2.53 ENST00000382936.3
ENST00000536901.1
ENST00000303277.2
transmembrane protein 129
chr7_+_65939543 2.51 ENST00000600021.1
HCG1983814; Uncharacterized protein
chr14_+_65171315 2.48 ENST00000394691.1
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr12_-_112037136 2.46 ENST00000608853.1
ataxin 2
chr21_+_37692481 2.44 ENST00000400485.1
MORC family CW-type zinc finger 3
chr19_-_10679644 2.35 ENST00000393599.2
cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
chr8_-_11058847 2.34 ENST00000297303.4
ENST00000416569.2
XK, Kell blood group complex subunit-related family, member 6
chr1_+_158969752 2.33 ENST00000566111.1
interferon, gamma-inducible protein 16
chrX_+_131157609 2.33 ENST00000496850.1
Serine/threonine-protein kinase MST4
chr3_-_49459878 2.30 ENST00000546031.1
ENST00000458307.2
ENST00000430521.1
aminomethyltransferase
chr14_-_69619291 2.29 ENST00000554215.1
ENST00000556847.1
DDB1 and CUL4 associated factor 5
chr16_+_2546033 2.28 ENST00000564543.1
ENST00000434757.2
Uncharacterized protein
TBC1 domain family, member 24
chr2_-_222437049 2.26 ENST00000541600.1
EPH receptor A4
chr17_-_4464081 2.24 ENST00000574154.1
gamma-glutamyltransferase 6
chr19_-_37329254 2.24 ENST00000356725.4
zinc finger protein 790
chr6_-_47277634 2.24 ENST00000296861.2
tumor necrosis factor receptor superfamily, member 21
chr3_-_124839648 2.21 ENST00000430155.2
solute carrier family 12, member 8
chr4_-_41216492 2.20 ENST00000503503.1
ENST00000509446.1
ENST00000503264.1
ENST00000508707.1
ENST00000508593.1
amyloid beta (A4) precursor protein-binding, family B, member 2
chr1_+_17575584 2.17 ENST00000375460.3
peptidyl arginine deiminase, type III
chr12_-_112037306 2.16 ENST00000535949.1
ENST00000542287.2
ENST00000377617.3
ENST00000550104.1
ataxin 2
chr19_-_10628117 2.16 ENST00000333430.4
sphingosine-1-phosphate receptor 5
chr11_-_63536113 2.14 ENST00000433688.1
ENST00000546282.2
chromosome 11 open reading frame 95
RP11-466C23.4
chr17_+_4901199 2.14 ENST00000320785.5
ENST00000574165.1
kinesin family member 1C
chr1_-_40782938 2.12 ENST00000372736.3
ENST00000372748.3
collagen, type IX, alpha 2
chr19_-_55865908 2.08 ENST00000590900.1
cytochrome c oxidase subunit VIb polypeptide 2 (testis)
chr16_+_67465016 2.07 ENST00000326152.5
hydroxysteroid (11-beta) dehydrogenase 2
chr1_+_154377669 2.06 ENST00000368485.3
ENST00000344086.4
interleukin 6 receptor
chr14_-_69619823 2.04 ENST00000341516.5
DDB1 and CUL4 associated factor 5
chr11_+_66036004 2.02 ENST00000311481.6
ENST00000527397.1
RAB1B, member RAS oncogene family
chr13_+_60971427 2.02 ENST00000535286.1
ENST00000377881.2
tudor domain containing 3
chr17_+_7748233 2.00 ENST00000570632.1
lysine (K)-specific demethylase 6B
chr12_+_19282713 1.97 ENST00000299275.6
ENST00000539256.1
ENST00000538714.1
pleckstrin homology domain containing, family A member 5
chr6_-_138428613 1.96 ENST00000421351.3
PERP, TP53 apoptosis effector
chr1_-_20812690 1.95 ENST00000375078.3
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr19_+_13229126 1.94 ENST00000292431.4
nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
chr5_-_157002749 1.94 ENST00000517905.1
ENST00000430702.2
ENST00000394020.1
ADAM metallopeptidase domain 19
chr4_+_78078304 1.93 ENST00000316355.5
ENST00000354403.5
ENST00000502280.1
cyclin G2
chr1_+_65613852 1.91 ENST00000327299.7
adenylate kinase 4
chr19_-_55866061 1.91 ENST00000588572.2
ENST00000593184.1
ENST00000589467.1
cytochrome c oxidase subunit VIb polypeptide 2 (testis)
chr8_+_22435762 1.91 ENST00000456545.1
PDZ and LIM domain 2 (mystique)
chr1_+_209929377 1.89 ENST00000400959.3
ENST00000367025.3
TRAF3 interacting protein 3
chr10_-_14880566 1.89 ENST00000378442.1
cerebral dopamine neurotrophic factor
chr6_-_34664612 1.86 ENST00000374023.3
ENST00000374026.3
chromosome 6 open reading frame 106
chr20_-_50808236 1.85 ENST00000361387.2
ZFP64 zinc finger protein
chr8_-_30670053 1.84 ENST00000518564.1
protein phosphatase 2, catalytic subunit, beta isozyme
chr19_+_10828795 1.84 ENST00000389253.4
ENST00000355667.6
ENST00000408974.4
dynamin 2
chr11_-_63684316 1.83 ENST00000301459.4
REST corepressor 2
chr19_-_19144243 1.82 ENST00000594445.1
ENST00000452918.2
ENST00000600377.1
ENST00000337018.6
SURP and G patch domain containing 2
chr4_-_41216619 1.82 ENST00000508676.1
ENST00000506352.1
ENST00000295974.8
amyloid beta (A4) precursor protein-binding, family B, member 2
chr6_-_3457256 1.81 ENST00000436008.2
solute carrier family 22, member 23
chr5_+_36608422 1.80 ENST00000381918.3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr3_-_150481218 1.79 ENST00000482706.1
siah E3 ubiquitin protein ligase 2
chr1_+_40505891 1.78 ENST00000372797.3
ENST00000372802.1
ENST00000449311.1
CAP, adenylate cyclase-associated protein 1 (yeast)
chr4_-_87770416 1.78 ENST00000273905.6
solute carrier family 10 (sodium/bile acid cotransporter), member 6
chr7_-_127671674 1.77 ENST00000478726.1
leucine rich repeat containing 4
chr3_+_41240925 1.76 ENST00000396183.3
ENST00000349496.5
ENST00000453024.1
catenin (cadherin-associated protein), beta 1, 88kDa
chr12_+_6308881 1.74 ENST00000382518.1
ENST00000536586.1
CD9 molecule
chr2_-_43453734 1.74 ENST00000282388.3
ZFP36 ring finger protein-like 2
chr12_-_48152853 1.72 ENST00000171000.4
Rap guanine nucleotide exchange factor (GEF) 3
chr1_+_209929494 1.71 ENST00000367026.3
TRAF3 interacting protein 3
chr5_+_131409476 1.71 ENST00000296871.2
colony stimulating factor 2 (granulocyte-macrophage)
chr3_-_10052849 1.70 ENST00000437616.1
ENST00000429065.2
AC022007.5
chr19_+_7710774 1.69 ENST00000602355.1
syntaxin binding protein 2
chr2_+_120770686 1.68 ENST00000331393.4
ENST00000443124.1
erythrocyte membrane protein band 4.1 like 5
chr19_+_11546153 1.68 ENST00000591946.1
ENST00000252455.2
ENST00000412601.1
protein kinase C substrate 80K-H
chr17_+_66511540 1.67 ENST00000588188.2
protein kinase, cAMP-dependent, regulatory, type I, alpha
chr19_+_11546093 1.67 ENST00000591462.1
protein kinase C substrate 80K-H
chr4_-_185747188 1.66 ENST00000507295.1
ENST00000504900.1
ENST00000281455.2
ENST00000454703.2
acyl-CoA synthetase long-chain family member 1
chrX_+_48916497 1.63 ENST00000496529.2
ENST00000376396.3
ENST00000422185.2
ENST00000603986.1
ENST00000536628.2
coiled-coil domain containing 120
chr19_+_37742773 1.63 ENST00000438770.2
ENST00000591116.1
ENST00000592712.1
AC012309.5
chr1_-_147245484 1.63 ENST00000271348.2
gap junction protein, alpha 5, 40kDa
chr6_+_43139037 1.63 ENST00000265354.4
serum response factor (c-fos serum response element-binding transcription factor)
chr13_-_39612176 1.63 ENST00000352251.3
ENST00000350125.3
proline and serine rich 1
chr4_+_26862313 1.60 ENST00000467087.1
ENST00000382009.3
ENST00000237364.5
stromal interaction molecule 2
chr1_-_11322551 1.58 ENST00000361445.4
mechanistic target of rapamycin (serine/threonine kinase)
chr11_+_8704298 1.58 ENST00000531978.1
ENST00000524496.1
ENST00000532359.1
ENST00000530022.1
ribosomal protein L27a
chr5_-_157002775 1.57 ENST00000257527.4
ADAM metallopeptidase domain 19
chr3_-_185216811 1.57 ENST00000421852.1
transmembrane protein 41A
chr13_+_52158610 1.57 ENST00000298125.5
WD repeat and FYVE domain containing 2
chr19_-_55866104 1.56 ENST00000326529.4
cytochrome c oxidase subunit VIb polypeptide 2 (testis)
chr1_-_6260896 1.56 ENST00000497965.1
ribosomal protein L22
chr4_+_2800722 1.56 ENST00000508385.1
SH3-domain binding protein 2
chr3_+_135684515 1.54 ENST00000264977.3
ENST00000490467.1
protein phosphatase 2, regulatory subunit B'', alpha
chrX_-_1572629 1.54 ENST00000534940.1
acetylserotonin O-methyltransferase-like
chr1_-_86861660 1.54 ENST00000486215.1
outer dense fiber of sperm tails 2-like
chr19_+_7701985 1.52 ENST00000595950.1
ENST00000441779.2
ENST00000221283.5
ENST00000414284.2
syntaxin binding protein 2
chr5_+_177540444 1.52 ENST00000274605.5
NEDD4 binding protein 3
chr9_+_116917807 1.51 ENST00000356083.3
collagen, type XXVII, alpha 1
chr2_-_39347524 1.51 ENST00000395038.2
ENST00000402219.2
son of sevenless homolog 1 (Drosophila)
chr1_-_54872059 1.51 ENST00000371320.3
single stranded DNA binding protein 3
chr3_+_138067666 1.49 ENST00000475711.1
ENST00000464896.1
muscle RAS oncogene homolog
chr18_+_34409069 1.48 ENST00000543923.1
ENST00000280020.5
ENST00000435985.2
ENST00000592521.1
ENST00000587139.1
KIAA1328
chr12_-_48152611 1.47 ENST00000389212.3
Rap guanine nucleotide exchange factor (GEF) 3
chr4_-_41216473 1.47 ENST00000513140.1
amyloid beta (A4) precursor protein-binding, family B, member 2
chr11_+_117198801 1.46 ENST00000527609.1
ENST00000533570.1
centrosomal protein 164kDa
chr2_-_99485825 1.45 ENST00000423771.1
KIAA1211-like
chr1_-_29508321 1.43 ENST00000546138.1
serine/arginine-rich splicing factor 4
chr16_-_66959429 1.43 ENST00000420652.1
ENST00000299759.6
Ras-related associated with diabetes
chrX_+_150151824 1.40 ENST00000455596.1
ENST00000448905.2
high mobility group box 3

Network of associatons between targets according to the STRING database.

First level regulatory network of TFAP2B

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
4.9 19.6 GO:1902910 regulation of monophenol monooxygenase activity(GO:0032771) positive regulation of monophenol monooxygenase activity(GO:0032773) negative regulation of catagen(GO:0051796) regulation of hair cycle by canonical Wnt signaling pathway(GO:0060901) positive regulation of melanosome transport(GO:1902910)
2.4 7.1 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
2.1 6.3 GO:0060489 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
1.8 9.2 GO:0018153 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
1.8 9.1 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
1.8 5.3 GO:1904784 NLRP1 inflammasome complex assembly(GO:1904784)
1.7 12.2 GO:0071461 cellular response to redox state(GO:0071461)
1.6 6.5 GO:1990927 vesicle-mediated cholesterol transport(GO:0090119) short-term synaptic potentiation(GO:1990926) calcium ion regulated lysosome exocytosis(GO:1990927)
1.5 4.6 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
1.4 5.6 GO:0060166 olfactory pit development(GO:0060166)
1.3 5.1 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
1.2 6.1 GO:0030807 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
1.2 3.6 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
1.1 13.1 GO:0035986 senescence-associated heterochromatin focus assembly(GO:0035986)
1.1 3.2 GO:1903526 negative regulation of membrane tubulation(GO:1903526)
1.0 4.9 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.9 5.2 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.8 3.3 GO:0099640 axo-dendritic protein transport(GO:0099640)
0.8 2.4 GO:0003294 atrial ventricular junction remodeling(GO:0003294) atrial cardiac muscle cell to AV node cell communication by electrical coupling(GO:0086044) bundle of His cell to Purkinje myocyte communication by electrical coupling(GO:0086054) Purkinje myocyte to ventricular cardiac muscle cell communication by electrical coupling(GO:0086055) regulation of Purkinje myocyte action potential(GO:0098906) vasomotion(GO:1990029)
0.8 6.3 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.7 3.0 GO:0009956 radial pattern formation(GO:0009956)
0.7 2.9 GO:0061324 glial cell fate determination(GO:0007403) canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324) regulation of chromatin-mediated maintenance of transcription(GO:1904499) positive regulation of chromatin-mediated maintenance of transcription(GO:1904501) regulation of euchromatin binding(GO:1904793)
0.7 5.0 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.6 1.7 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.6 2.2 GO:0097252 oligodendrocyte apoptotic process(GO:0097252)
0.6 9.9 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.5 20.3 GO:0031581 hemidesmosome assembly(GO:0031581)
0.5 1.6 GO:0060532 bronchus cartilage development(GO:0060532) lung smooth muscle development(GO:0061145)
0.5 2.2 GO:1990785 response to water-immersion restraint stress(GO:1990785)
0.5 5.9 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.5 1.6 GO:1904204 regulation of skeletal muscle hypertrophy(GO:1904204)
0.5 2.6 GO:0044858 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.5 10.2 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.5 5.6 GO:0072656 maintenance of protein location in mitochondrion(GO:0072656)
0.5 1.5 GO:2000744 anterior head development(GO:0097065) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744)
0.5 1.4 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.5 2.8 GO:0010193 response to ozone(GO:0010193)
0.4 1.3 GO:0070318 response to anoxia(GO:0034059) positive regulation of G0 to G1 transition(GO:0070318)
0.4 1.3 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.4 2.2 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.4 6.8 GO:0035634 response to stilbenoid(GO:0035634)
0.4 9.9 GO:0090026 positive regulation of monocyte chemotaxis(GO:0090026)
0.4 1.2 GO:0051255 spindle midzone assembly(GO:0051255)
0.4 4.0 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.4 3.6 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
0.3 10.1 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.3 3.1 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.3 1.0 GO:0098904 regulation of AV node cell action potential(GO:0098904)
0.3 5.1 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.3 0.7 GO:0071895 odontoblast differentiation(GO:0071895)
0.3 5.8 GO:1901750 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.3 7.0 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.3 1.5 GO:1904693 midbrain morphogenesis(GO:1904693)
0.3 2.9 GO:0003084 positive regulation of systemic arterial blood pressure(GO:0003084)
0.3 4.6 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.3 1.1 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.3 1.4 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.3 1.1 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.3 4.1 GO:0035092 sperm chromatin condensation(GO:0035092)
0.3 1.1 GO:0001971 negative regulation of activation of membrane attack complex(GO:0001971)
0.3 2.0 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.2 1.7 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.2 0.7 GO:1902908 regulation of melanosome transport(GO:1902908)
0.2 2.4 GO:0070779 gamma-aminobutyric acid biosynthetic process(GO:0009449) D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.2 1.3 GO:0002317 plasma cell differentiation(GO:0002317)
0.2 0.7 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.2 1.5 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.2 2.5 GO:2001181 positive regulation of interleukin-5 secretion(GO:2000664) positive regulation of interleukin-10 secretion(GO:2001181)
0.2 1.0 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.2 0.8 GO:0014050 negative regulation of glutamate secretion(GO:0014050)
0.2 3.5 GO:0060019 radial glial cell differentiation(GO:0060019)
0.2 2.8 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.2 0.8 GO:0060152 peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
0.2 1.2 GO:0006311 meiotic gene conversion(GO:0006311)
0.2 2.4 GO:0048102 autophagic cell death(GO:0048102)
0.2 1.9 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.2 0.9 GO:0035900 response to isolation stress(GO:0035900)
0.2 4.9 GO:0051639 actin filament network formation(GO:0051639)
0.2 1.2 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.2 1.6 GO:0051056 regulation of small GTPase mediated signal transduction(GO:0051056)
0.2 0.5 GO:2000657 regulation of apolipoprotein binding(GO:2000656) negative regulation of apolipoprotein binding(GO:2000657)
0.2 6.1 GO:0060441 epithelial tube branching involved in lung morphogenesis(GO:0060441)
0.2 1.7 GO:0009414 response to water deprivation(GO:0009414)
0.2 0.8 GO:0039019 pronephric nephron development(GO:0039019)
0.2 0.8 GO:0075509 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.2 0.6 GO:0002384 hepatic immune response(GO:0002384)
0.1 0.6 GO:0046946 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.1 0.3 GO:0042662 negative regulation of mesodermal cell fate specification(GO:0042662) regulation of midbrain dopaminergic neuron differentiation(GO:1904956)
0.1 2.4 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.1 0.4 GO:2000819 regulation of nucleotide-excision repair(GO:2000819)
0.1 1.7 GO:0044539 long-chain fatty acid import(GO:0044539)
0.1 1.0 GO:0090625 mRNA cleavage involved in gene silencing by siRNA(GO:0090625)
0.1 2.3 GO:0002934 desmosome organization(GO:0002934)
0.1 0.7 GO:0031291 Ran protein signal transduction(GO:0031291)
0.1 0.5 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.1 1.8 GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.1 0.8 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.1 0.4 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
0.1 3.4 GO:0051412 response to corticosterone(GO:0051412)
0.1 0.1 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.1 1.8 GO:0006228 UTP biosynthetic process(GO:0006228)
0.1 0.7 GO:0060523 prostate epithelial cord elongation(GO:0060523) prostate gland morphogenetic growth(GO:0060737)
0.1 9.8 GO:0015701 bicarbonate transport(GO:0015701)
0.1 0.4 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.1 5.2 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.1 0.5 GO:0007571 age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
0.1 0.3 GO:0071879 UDP-glucose catabolic process(GO:0006258) positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.1 13.9 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.1 1.9 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.1 0.8 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.1 0.6 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 0.3 GO:0070666 tolerance induction to self antigen(GO:0002513) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.1 1.2 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.1 0.5 GO:2001184 positive regulation of interleukin-12 secretion(GO:2001184)
0.1 1.3 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.1 0.6 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.1 3.4 GO:0006491 N-glycan processing(GO:0006491)
0.1 10.1 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.1 8.1 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.1 1.0 GO:1904590 negative regulation of protein import into nucleus(GO:0042308) negative regulation of protein import(GO:1904590)
0.1 0.5 GO:0071543 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.1 0.5 GO:0048388 endosomal lumen acidification(GO:0048388) necroptotic signaling pathway(GO:0097527)
0.1 1.1 GO:0046689 response to mercury ion(GO:0046689)
0.1 1.8 GO:0097119 postsynaptic density protein 95 clustering(GO:0097119)
0.1 1.2 GO:0009173 UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.1 2.0 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.1 3.9 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.1 0.7 GO:1905247 regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902959) positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) regulation of aspartic-type peptidase activity(GO:1905245) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.1 3.3 GO:0048147 negative regulation of fibroblast proliferation(GO:0048147)
0.1 0.5 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.1 0.7 GO:0097105 postsynaptic membrane assembly(GO:0097104) presynaptic membrane assembly(GO:0097105)
0.1 0.2 GO:0050894 determination of affect(GO:0050894)
0.1 1.9 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.1 0.5 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.1 1.3 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.1 0.5 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1 9.6 GO:0070268 cornification(GO:0070268)
0.1 0.8 GO:0097267 omega-hydroxylase P450 pathway(GO:0097267)
0.1 3.6 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.1 0.5 GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372)
0.1 1.1 GO:0098903 regulation of membrane repolarization during action potential(GO:0098903)
0.1 2.6 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.1 2.8 GO:0033006 regulation of mast cell activation involved in immune response(GO:0033006) regulation of mast cell degranulation(GO:0043304)
0.1 2.6 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.1 0.9 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.1 2.6 GO:0006376 mRNA splice site selection(GO:0006376)
0.1 0.2 GO:0021919 BMP signaling pathway involved in spinal cord dorsal/ventral patterning(GO:0021919)
0.1 0.9 GO:0019388 galactose catabolic process(GO:0019388)
0.1 0.3 GO:0046092 deoxycytidine metabolic process(GO:0046092)
0.1 0.1 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.1 0.4 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.1 1.0 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.1 0.1 GO:0042746 regulation of circadian sleep/wake cycle, wakefulness(GO:0010840) positive regulation of circadian sleep/wake cycle, wakefulness(GO:0010841) circadian sleep/wake cycle, wakefulness(GO:0042746)
0.0 1.2 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 2.3 GO:0032731 positive regulation of interleukin-1 beta production(GO:0032731)
0.0 1.7 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0 0.3 GO:0019557 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.0 0.4 GO:0033590 response to cobalamin(GO:0033590) cellular response to erythropoietin(GO:0036018)
0.0 0.5 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.5 GO:0071421 manganese ion transmembrane transport(GO:0071421)
0.0 1.0 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.4 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 1.2 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.7 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.0 0.1 GO:0003192 mitral valve formation(GO:0003192)
0.0 0.8 GO:0061298 retina vasculature development in camera-type eye(GO:0061298)
0.0 0.6 GO:0033327 Leydig cell differentiation(GO:0033327)
0.0 0.2 GO:0052805 histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.0 6.1 GO:0007173 epidermal growth factor receptor signaling pathway(GO:0007173)
0.0 0.3 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.4 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.0 1.3 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.3 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 6.7 GO:0001764 neuron migration(GO:0001764)
0.0 1.8 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.3 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.0 0.7 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0 1.1 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.0 2.5 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 0.5 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.0 0.7 GO:2000059 negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000059)
0.0 2.9 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.4 GO:0030497 fatty acid elongation(GO:0030497)
0.0 0.6 GO:0070987 error-free translesion synthesis(GO:0070987)
0.0 3.2 GO:0043647 inositol phosphate metabolic process(GO:0043647)
0.0 0.4 GO:0050775 positive regulation of dendrite morphogenesis(GO:0050775)
0.0 2.4 GO:0030520 intracellular estrogen receptor signaling pathway(GO:0030520)
0.0 0.6 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.8 GO:0048169 regulation of long-term neuronal synaptic plasticity(GO:0048169)
0.0 4.0 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.2 GO:0032815 negative regulation of natural killer cell activation(GO:0032815)
0.0 0.2 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 10.5 GO:0016197 endosomal transport(GO:0016197)
0.0 1.5 GO:0032259 methylation(GO:0032259)
0.0 0.5 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002) fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.3 GO:0070233 negative regulation of T cell apoptotic process(GO:0070233)
0.0 1.0 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 0.1 GO:0021984 adenohypophysis development(GO:0021984)
0.0 0.5 GO:2000505 regulation of energy homeostasis(GO:2000505)
0.0 0.6 GO:0035066 positive regulation of histone acetylation(GO:0035066)
0.0 0.2 GO:0035524 proline transmembrane transport(GO:0035524)
0.0 3.0 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0 0.5 GO:0010800 positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0 0.2 GO:0045542 positive regulation of cholesterol biosynthetic process(GO:0045542)
0.0 1.4 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.0 GO:0071315 cellular response to morphine(GO:0071315) cellular response to isoquinoline alkaloid(GO:0071317)
0.0 0.2 GO:0072402 response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423)
0.0 1.7 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.9 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.0 2.0 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.9 GO:0060348 bone development(GO:0060348)
0.0 0.1 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.0 1.9 GO:1902017 regulation of cilium assembly(GO:1902017)
0.0 1.6 GO:0048813 dendrite morphogenesis(GO:0048813)
0.0 1.9 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 0.8 GO:0006469 negative regulation of protein kinase activity(GO:0006469)
0.0 0.2 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
0.0 0.0 GO:1901857 positive regulation of cellular respiration(GO:1901857)
0.0 0.5 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.0 0.2 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.8 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.0 0.4 GO:1903504 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 2.2 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.0 0.2 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.1 GO:0001707 mesoderm formation(GO:0001707) mesoderm morphogenesis(GO:0048332)
0.0 2.0 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.1 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
0.0 0.3 GO:0018027 peptidyl-lysine dimethylation(GO:0018027)
0.0 0.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.7 GO:0051220 cytoplasmic sequestering of protein(GO:0051220)
0.0 1.0 GO:0006305 DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.0 0.2 GO:1904886 beta-catenin destruction complex disassembly(GO:1904886)
0.0 0.2 GO:0032228 regulation of synaptic transmission, GABAergic(GO:0032228)
0.0 0.5 GO:0007249 I-kappaB kinase/NF-kappaB signaling(GO:0007249)
0.0 0.9 GO:0000045 autophagosome assembly(GO:0000045)
0.0 0.3 GO:0002209 behavioral fear response(GO:0001662) behavioral defense response(GO:0002209)
0.0 2.0 GO:0006024 glycosaminoglycan biosynthetic process(GO:0006024)
0.0 0.0 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.0 0.3 GO:0040020 regulation of meiotic nuclear division(GO:0040020)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 5.8 GO:0060187 cell pole(GO:0060187)
1.1 13.1 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.8 5.3 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.5 6.5 GO:0032009 early phagosome(GO:0032009)
0.4 5.9 GO:0030061 mitochondrial crista(GO:0030061)
0.4 5.2 GO:0002116 semaphorin receptor complex(GO:0002116)
0.4 2.9 GO:0070369 Scrib-APC-beta-catenin complex(GO:0034750) beta-catenin-TCF7L2 complex(GO:0070369)
0.4 2.1 GO:0005594 collagen type IX trimer(GO:0005594)
0.3 3.1 GO:0044194 cytolytic granule(GO:0044194)
0.3 2.4 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.3 2.3 GO:0016272 prefoldin complex(GO:0016272)
0.3 4.8 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.3 1.4 GO:0005606 laminin-1 complex(GO:0005606)
0.3 1.0 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.3 4.6 GO:0000813 ESCRT I complex(GO:0000813)
0.3 0.8 GO:0097444 spine apparatus(GO:0097444)
0.2 0.5 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.2 1.4 GO:0097513 myosin II filament(GO:0097513)
0.2 16.5 GO:0045095 keratin filament(GO:0045095)
0.2 2.6 GO:0030478 actin cap(GO:0030478)
0.2 2.5 GO:0045179 apical cortex(GO:0045179)
0.2 0.2 GO:0030893 meiotic cohesin complex(GO:0030893)
0.2 2.0 GO:0030057 desmosome(GO:0030057)
0.1 1.0 GO:0033553 rDNA heterochromatin(GO:0033553)
0.1 13.7 GO:0008287 protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.1 9.6 GO:0001533 cornified envelope(GO:0001533)
0.1 5.6 GO:0097228 sperm principal piece(GO:0097228)
0.1 0.6 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 5.6 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 1.9 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.1 3.0 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 3.2 GO:0001891 phagocytic cup(GO:0001891)
0.1 14.8 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.1 2.9 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 15.7 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 1.5 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 4.2 GO:0044295 axonal growth cone(GO:0044295)
0.1 0.8 GO:0070847 core mediator complex(GO:0070847)
0.1 1.0 GO:0031931 TORC1 complex(GO:0031931)
0.1 4.8 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.1 1.6 GO:0097539 ciliary transition fiber(GO:0097539)
0.1 12.1 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 17.8 GO:0031225 anchored component of membrane(GO:0031225)
0.1 0.5 GO:0097427 microtubule bundle(GO:0097427)
0.1 6.4 GO:0005882 intermediate filament(GO:0005882)
0.1 2.3 GO:0035145 exon-exon junction complex(GO:0035145)
0.1 1.0 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 0.6 GO:0005663 DNA replication factor C complex(GO:0005663)
0.1 1.0 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.1 4.6 GO:0005844 polysome(GO:0005844)
0.1 0.5 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.1 1.4 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.1 8.8 GO:0005604 basement membrane(GO:0005604)
0.1 0.9 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 0.7 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.1 3.3 GO:1904115 axon cytoplasm(GO:1904115)
0.0 1.2 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.4 GO:0043196 varicosity(GO:0043196)
0.0 1.7 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 1.7 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 1.0 GO:0035102 PRC1 complex(GO:0035102)
0.0 1.6 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.2 GO:0031251 PAN complex(GO:0031251)
0.0 0.1 GO:0016600 flotillin complex(GO:0016600)
0.0 1.2 GO:0071437 invadopodium(GO:0071437)
0.0 0.7 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.3 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 1.0 GO:0043194 axon initial segment(GO:0043194)
0.0 5.7 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.8 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 1.9 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 6.4 GO:0030426 growth cone(GO:0030426)
0.0 1.7 GO:0035861 site of double-strand break(GO:0035861)
0.0 1.1 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 3.8 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 1.2 GO:0099738 cell cortex region(GO:0099738)
0.0 0.4 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 2.1 GO:0005871 kinesin complex(GO:0005871)
0.0 1.1 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.9 GO:0051233 spindle midzone(GO:0051233)
0.0 0.1 GO:0030118 clathrin coat(GO:0030118)
0.0 1.8 GO:0031594 neuromuscular junction(GO:0031594)
0.0 1.2 GO:0000795 synaptonemal complex(GO:0000795)
0.0 15.6 GO:0031012 extracellular matrix(GO:0031012)
0.0 1.0 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 1.5 GO:0060170 ciliary membrane(GO:0060170)
0.0 0.6 GO:0005922 connexon complex(GO:0005922)
0.0 1.3 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.1 GO:0070931 Golgi-associated vesicle lumen(GO:0070931)
0.0 0.4 GO:0031143 pseudopodium(GO:0031143)
0.0 2.9 GO:0016605 PML body(GO:0016605)
0.0 0.2 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.1 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.4 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.1 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.7 GO:0034399 nuclear periphery(GO:0034399)
0.0 0.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 8.9 GO:0005925 focal adhesion(GO:0005925)
0.0 0.6 GO:0090544 BAF-type complex(GO:0090544)
0.0 0.3 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.1 GO:0032021 NELF complex(GO:0032021)
0.0 0.7 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 7.6 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
1.7 5.0 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
1.2 4.9 GO:0004047 aminomethyltransferase activity(GO:0004047)
1.0 12.2 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.9 11.3 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.8 3.3 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.8 2.4 GO:0086078 gap junction channel activity involved in atrial cardiac muscle cell-AV node cell electrical coupling(GO:0086076) gap junction channel activity involved in bundle of His cell-Purkinje myocyte electrical coupling(GO:0086078) gap junction channel activity involved in Purkinje myocyte-ventricular cardiac muscle cell electrical coupling(GO:0086079)
0.8 8.5 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.7 14.1 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.7 2.1 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.7 15.2 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.7 2.0 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.7 9.8 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.6 5.6 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.6 3.0 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.6 16.7 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.6 5.1 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.5 3.2 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.5 1.6 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
0.5 1.4 GO:0008301 DNA binding, bending(GO:0008301)
0.4 2.2 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.4 1.3 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.4 7.8 GO:0008179 adenylate cyclase binding(GO:0008179)
0.4 5.6 GO:0070324 thyroid hormone binding(GO:0070324)
0.4 2.8 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.4 6.3 GO:0008199 ferric iron binding(GO:0008199)
0.3 1.4 GO:0001515 opioid peptide activity(GO:0001515)
0.3 6.1 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.3 1.3 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.3 1.6 GO:0010736 serum response element binding(GO:0010736)
0.3 5.8 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.3 3.2 GO:0030348 syntaxin-3 binding(GO:0030348)
0.3 1.9 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.3 2.8 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.3 1.1 GO:0000822 inositol hexakisphosphate binding(GO:0000822) inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.3 1.8 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.3 2.0 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.2 27.2 GO:0097110 scaffold protein binding(GO:0097110)
0.2 13.6 GO:0046875 ephrin receptor binding(GO:0046875)
0.2 0.7 GO:0072544 L-DOPA receptor activity(GO:0035643) L-DOPA binding(GO:0072544)
0.2 2.4 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.2 5.2 GO:0030215 semaphorin receptor binding(GO:0030215)
0.2 4.2 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.2 0.6 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
0.2 3.9 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.2 2.1 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.2 0.8 GO:0004967 glucagon receptor activity(GO:0004967)
0.2 2.6 GO:0045159 myosin II binding(GO:0045159)
0.2 1.0 GO:0071253 connexin binding(GO:0071253)
0.2 1.5 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.2 2.2 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.2 7.4 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.2 9.9 GO:0042379 chemokine receptor binding(GO:0042379)
0.1 0.6 GO:0033823 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.1 0.6 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.1 1.9 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.1 4.8 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 0.6 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.1 0.9 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.1 3.0 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1 0.8 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.1 3.6 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.1 4.5 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.1 1.2 GO:0004849 uridine kinase activity(GO:0004849)
0.1 1.5 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.1 2.5 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.1 0.5 GO:0010861 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.1 1.4 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.1 0.4 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
0.1 4.2 GO:0001968 fibronectin binding(GO:0001968)
0.1 2.5 GO:0043274 phospholipase binding(GO:0043274)
0.1 0.7 GO:0050815 phosphoserine binding(GO:0050815)
0.1 2.1 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 0.7 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.1 0.3 GO:0005199 structural constituent of cell wall(GO:0005199)
0.1 0.4 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.1 1.8 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 13.2 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 0.5 GO:0052842 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.1 4.6 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 0.3 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 1.9 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 0.8 GO:0004969 histamine receptor activity(GO:0004969)
0.1 1.9 GO:0000339 RNA cap binding(GO:0000339)
0.1 0.9 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.1 0.5 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.1 4.6 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 1.3 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.1 1.8 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.1 0.6 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 9.4 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.1 0.4 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.1 9.6 GO:0051087 chaperone binding(GO:0051087)
0.1 1.7 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.1 1.7 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 4.7 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 1.4 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 1.2 GO:0008494 translation activator activity(GO:0008494)
0.1 0.2 GO:0036033 mediator complex binding(GO:0036033)
0.1 5.6 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 0.4 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.1 2.9 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.1 1.7 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.1 0.2 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.1 1.1 GO:0005537 mannose binding(GO:0005537)
0.0 1.0 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.0 0.5 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.3 GO:0004137 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.0 1.4 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 2.6 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.5 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.0 1.2 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 1.0 GO:0035198 miRNA binding(GO:0035198)
0.0 0.7 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.3 GO:0016841 ammonia-lyase activity(GO:0016841)
0.0 1.2 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 1.1 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 1.0 GO:0001013 RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0 0.5 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.2 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 7.6 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 1.4 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.0 0.9 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.3 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.8 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.6 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.6 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 1.1 GO:0001848 complement binding(GO:0001848)
0.0 0.7 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.2 GO:0045545 syndecan binding(GO:0045545)
0.0 0.6 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 9.2 GO:0030674 protein binding, bridging(GO:0030674)
0.0 0.2 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 2.9 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.5 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.7 GO:0019956 chemokine binding(GO:0019956)
0.0 5.5 GO:0005125 cytokine activity(GO:0005125)
0.0 0.9 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.5 GO:0005109 frizzled binding(GO:0005109)
0.0 1.1 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 1.0 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.4 GO:0005112 Notch binding(GO:0005112)
0.0 0.9 GO:0015248 sterol transporter activity(GO:0015248)
0.0 2.6 GO:0003777 microtubule motor activity(GO:0003777)
0.0 13.6 GO:0003779 actin binding(GO:0003779)
0.0 0.5 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.7 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 2.7 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.4 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 2.8 GO:0044325 ion channel binding(GO:0044325)
0.0 0.5 GO:0004707 MAP kinase activity(GO:0004707)
0.0 3.8 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.3 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.6 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.4 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.8 GO:0043022 ribosome binding(GO:0043022)
0.0 0.4 GO:0015026 coreceptor activity(GO:0015026)
0.0 1.1 GO:0019213 deacetylase activity(GO:0019213)
0.0 2.3 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 13.7 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.3 1.5 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.3 11.6 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.2 23.4 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.2 10.7 PID EPHA FWDPATHWAY EPHA forward signaling
0.2 6.2 ST G ALPHA S PATHWAY G alpha s Pathway
0.2 5.8 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.2 5.4 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.2 8.0 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 10.3 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.1 9.3 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 1.9 PID S1P S1P4 PATHWAY S1P4 pathway
0.1 0.9 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.1 3.3 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.1 4.8 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.1 10.9 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 3.2 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.1 4.8 PID LKB1 PATHWAY LKB1 signaling events
0.1 0.9 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 7.4 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.1 3.1 PID PI3KCI PATHWAY Class I PI3K signaling events
0.1 1.1 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.1 1.7 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.1 0.4 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 3.6 NABA COLLAGENS Genes encoding collagen proteins
0.0 3.2 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 2.8 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.6 ST STAT3 PATHWAY STAT3 Pathway
0.0 1.1 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 2.8 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 1.3 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 2.2 PID ATR PATHWAY ATR signaling pathway
0.0 13.9 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 2.4 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 9.4 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.4 PID FOXO PATHWAY FoxO family signaling
0.0 2.3 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.6 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 0.7 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 0.4 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 2.1 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.0 7.6 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.4 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.3 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.4 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.7 PID BMP PATHWAY BMP receptor signaling
0.0 0.5 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 2.9 NABA MATRISOME ASSOCIATED Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 14.7 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.4 15.0 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.3 19.3 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.3 3.6 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.2 14.5 REACTOME G1 PHASE Genes involved in G1 Phase
0.2 3.2 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.2 0.7 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.2 2.8 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.2 3.4 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 5.3 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.1 6.6 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 3.2 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.1 3.1 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 7.9 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.1 1.3 REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE Genes involved in p53-Dependent G1 DNA Damage Response
0.1 1.2 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.1 6.6 REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING Genes involved in Integrin alphaIIb beta3 signaling
0.1 5.1 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 2.4 REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION Genes involved in Glucagon signaling in metabolic regulation
0.1 1.8 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 5.6 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.1 3.4 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 0.9 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.1 1.1 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 3.8 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.1 3.3 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.1 2.4 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 2.1 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 2.6 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.1 5.3 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.4 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.0 5.0 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 4.3 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.6 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 10.3 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 1.6 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.8 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.0 1.4 REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
0.0 1.1 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 1.1 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 1.1 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.5 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 2.9 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 0.9 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.8 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 7.9 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.9 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 1.2 REACTOME TRIGLYCERIDE BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.0 2.3 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 2.0 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.3 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.6 REACTOME GAP JUNCTION TRAFFICKING Genes involved in Gap junction trafficking
0.0 0.5 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.2 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.5 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.1 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.7 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.5 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.8 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.5 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.6 REACTOME FGFR LIGAND BINDING AND ACTIVATION Genes involved in FGFR ligand binding and activation
0.0 0.9 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 1.3 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.2 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 0.4 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 0.2 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 2.3 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 0.3 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription