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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for TFAP2E

Z-value: 0.66

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Transcription factors associated with TFAP2E

Gene Symbol Gene ID Gene Info
TFAP2E
ENSG00000116819.6 transcription factor AP-2 epsilon

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TFAP2Ehg19_v2_chr1_+_36038971_360389710.233.3e-01Click!

Activity profile of TFAP2E motif

Sorted Z-values of TFAP2E motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr14_+_24837226 3.49 ENST00000554050.1
ENST00000554903.1
ENST00000554779.1
ENST00000250373.4
ENST00000553708.1
NFATC4
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
chr19_-_43969796 3.42 ENST00000244333.3
LYPD3
LY6/PLAUR domain containing 3
chr3_+_50192833 2.79 ENST00000426511.1
SEMA3F
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr2_+_75061108 2.59 ENST00000290573.2
HK2
hexokinase 2
chr19_-_54676846 2.01 ENST00000301187.4
TMC4
transmembrane channel-like 4
chrX_+_115567767 1.97 ENST00000371900.4
SLC6A14
solute carrier family 6 (amino acid transporter), member 14
chr19_-_54676884 1.94 ENST00000376591.4
TMC4
transmembrane channel-like 4
chr17_-_39769005 1.90 ENST00000301653.4
ENST00000593067.1
KRT16
keratin 16
chr2_-_45236540 1.89 ENST00000303077.6
SIX2
SIX homeobox 2
chr22_+_31608219 1.56 ENST00000406516.1
ENST00000444929.2
ENST00000331728.4
LIMK2
LIM domain kinase 2
chr22_+_31644309 1.46 ENST00000425203.1
LIMK2
LIM domain kinase 2
chr19_-_39264072 1.39 ENST00000599035.1
ENST00000378626.4
LGALS7
lectin, galactoside-binding, soluble, 7
chr22_+_31644388 1.35 ENST00000333611.4
ENST00000340552.4
LIMK2
LIM domain kinase 2
chr1_+_35225339 1.09 ENST00000339480.1
GJB4
gap junction protein, beta 4, 30.3kDa
chr2_-_241831424 0.97 ENST00000402775.2
ENST00000307486.8
C2orf54
chromosome 2 open reading frame 54
chr10_-_98273668 0.92 ENST00000357947.3
TLL2
tolloid-like 2
chr3_-_69591727 0.91 ENST00000459638.1
FRMD4B
FERM domain containing 4B
chr6_+_292051 0.89 ENST00000344450.5
DUSP22
dual specificity phosphatase 22
chr4_+_154387480 0.87 ENST00000409663.3
ENST00000440693.1
ENST00000409959.3
KIAA0922
KIAA0922
chr6_+_7108210 0.83 ENST00000467782.1
ENST00000334984.6
ENST00000349384.6
RREB1
ras responsive element binding protein 1
chr6_+_7107999 0.82 ENST00000491191.1
ENST00000379938.2
ENST00000471433.1
RREB1
ras responsive element binding protein 1
chr1_-_201346761 0.78 ENST00000455702.1
ENST00000422165.1
ENST00000367318.5
ENST00000367320.2
ENST00000438742.1
ENST00000412633.1
ENST00000458432.2
ENST00000421663.2
ENST00000367322.1
ENST00000509001.1
TNNT2
troponin T type 2 (cardiac)
chr22_+_35653445 0.76 ENST00000420166.1
ENST00000444518.2
ENST00000455359.1
ENST00000216106.5
HMGXB4
HMG box domain containing 4
chr12_+_75784850 0.75 ENST00000550916.1
ENST00000435775.1
ENST00000378689.2
ENST00000378692.3
ENST00000320460.4
ENST00000547164.1
GLIPR1L2
GLI pathogenesis-related 1 like 2
chr19_-_11039261 0.67 ENST00000590329.1
ENST00000587943.1
ENST00000585858.1
ENST00000586748.1
ENST00000586575.1
ENST00000253031.2
YIPF2
Yip1 domain family, member 2
chr1_+_43148625 0.66 ENST00000436427.1
YBX1
Y box binding protein 1
chr19_+_4969116 0.66 ENST00000588337.1
ENST00000159111.4
ENST00000381759.4
KDM4B
lysine (K)-specific demethylase 4B
chr19_+_54960358 0.62 ENST00000439657.1
ENST00000376514.2
ENST00000376526.4
ENST00000436479.1
LENG8
leukocyte receptor cluster (LRC) member 8
chr19_-_11039188 0.58 ENST00000588347.1
YIPF2
Yip1 domain family, member 2
chr4_-_82393052 0.57 ENST00000335927.7
ENST00000504863.1
ENST00000264400.2
RASGEF1B
RasGEF domain family, member 1B
chr3_-_48130314 0.56 ENST00000439356.1
ENST00000395734.3
ENST00000426837.2
MAP4
microtubule-associated protein 4
chr17_+_36584662 0.56 ENST00000431231.2
ENST00000437668.3
ARHGAP23
Rho GTPase activating protein 23
chr1_+_901847 0.53 ENST00000379410.3
ENST00000379409.2
ENST00000379407.3
PLEKHN1
pleckstrin homology domain containing, family N member 1
chr14_-_60952739 0.53 ENST00000555476.1
ENST00000321731.3
C14orf39
chromosome 14 open reading frame 39
chr17_+_48423453 0.50 ENST00000017003.2
ENST00000509778.1
ENST00000507602.1
XYLT2
xylosyltransferase II
chr11_-_65625014 0.50 ENST00000534784.1
CFL1
cofilin 1 (non-muscle)
chr9_+_128024067 0.49 ENST00000461379.1
ENST00000394084.1
ENST00000394105.2
ENST00000470056.1
ENST00000394104.2
ENST00000265956.4
ENST00000394083.2
ENST00000495955.1
ENST00000467750.1
ENST00000297933.6
GAPVD1
GTPase activating protein and VPS9 domains 1
chr6_+_42531798 0.46 ENST00000372903.2
ENST00000372899.1
ENST00000372901.1
UBR2
ubiquitin protein ligase E3 component n-recognin 2
chr1_-_154531095 0.46 ENST00000292211.4
UBE2Q1
ubiquitin-conjugating enzyme E2Q family member 1
chr11_+_118478313 0.45 ENST00000356063.5
PHLDB1
pleckstrin homology-like domain, family B, member 1
chr6_+_7107830 0.44 ENST00000379933.3
RREB1
ras responsive element binding protein 1
chr4_+_75480629 0.44 ENST00000380846.3
AREGB
amphiregulin B
chr6_+_150070857 0.42 ENST00000544496.1
PCMT1
protein-L-isoaspartate (D-aspartate) O-methyltransferase
chr11_+_64009072 0.42 ENST00000535135.1
ENST00000394540.3
FKBP2
FK506 binding protein 2, 13kDa
chrX_+_51636629 0.41 ENST00000375722.1
ENST00000326587.7
ENST00000375695.2
MAGED1
melanoma antigen family D, 1
chr3_+_51428704 0.37 ENST00000323686.4
RBM15B
RNA binding motif protein 15B
chr1_-_9189144 0.37 ENST00000414642.2
GPR157
G protein-coupled receptor 157
chr19_+_13229126 0.36 ENST00000292431.4
NACC1
nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
chr11_-_61062762 0.35 ENST00000335613.5
VWCE
von Willebrand factor C and EGF domains
chr7_-_140624499 0.35 ENST00000288602.6
BRAF
v-raf murine sarcoma viral oncogene homolog B
chr3_-_136471204 0.33 ENST00000480733.1
ENST00000383202.2
ENST00000236698.5
ENST00000434713.2
STAG1
stromal antigen 1
chrX_+_131157322 0.31 ENST00000481105.1
ENST00000354719.6
ENST00000394335.2
MST4
Serine/threonine-protein kinase MST4
chr7_-_23053719 0.31 ENST00000432176.2
ENST00000440481.1
FAM126A
family with sequence similarity 126, member A
chr1_-_32801825 0.31 ENST00000329421.7
MARCKSL1
MARCKS-like 1
chr1_+_9005917 0.29 ENST00000549778.1
ENST00000480186.3
ENST00000377443.2
ENST00000377436.3
ENST00000377442.2
CA6
carbonic anhydrase VI
chr3_-_55521323 0.28 ENST00000264634.4
WNT5A
wingless-type MMTV integration site family, member 5A
chr4_-_82393009 0.28 ENST00000436139.2
RASGEF1B
RasGEF domain family, member 1B
chr1_+_211433275 0.27 ENST00000367005.4
RCOR3
REST corepressor 3
chr12_+_57984965 0.27 ENST00000540759.2
ENST00000551772.1
ENST00000550465.1
ENST00000354947.5
PIP4K2C
phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
chr5_-_115152651 0.26 ENST00000250535.4
CDO1
cysteine dioxygenase type 1
chr16_-_72698834 0.26 ENST00000570152.1
ENST00000561611.2
ENST00000570035.1
AC004158.2
AC004158.2
chr3_+_105086056 0.26 ENST00000472644.2
ALCAM
activated leukocyte cell adhesion molecule
chr7_-_23053693 0.26 ENST00000409763.1
ENST00000409923.1
FAM126A
family with sequence similarity 126, member A
chr11_-_65624415 0.26 ENST00000524553.1
ENST00000527344.1
CFL1
cofilin 1 (non-muscle)
chr2_+_232572361 0.26 ENST00000409321.1
PTMA
prothymosin, alpha
chr5_+_133984462 0.25 ENST00000398844.2
ENST00000322887.4
SEC24A
SEC24 family member A
chr11_+_66045634 0.24 ENST00000528852.1
ENST00000311445.6
CNIH2
cornichon family AMPA receptor auxiliary protein 2
chr16_+_56623433 0.23 ENST00000570176.1
MT3
metallothionein 3
chr1_+_214163033 0.23 ENST00000607425.1
PROX1
prospero homeobox 1
chr6_+_37787262 0.22 ENST00000287218.4
ZFAND3
zinc finger, AN1-type domain 3
chrX_+_131157290 0.22 ENST00000394334.2
MST4
Serine/threonine-protein kinase MST4
chr1_-_114355083 0.21 ENST00000261441.5
RSBN1
round spermatid basic protein 1
chrX_+_49028265 0.21 ENST00000376322.3
ENST00000376327.5
PLP2
proteolipid protein 2 (colonic epithelium-enriched)
chr1_+_104068312 0.21 ENST00000524631.1
ENST00000531883.1
ENST00000533099.1
ENST00000527062.1
RNPC3
RNA-binding region (RNP1, RRM) containing 3
chr19_+_36195467 0.20 ENST00000426659.2
ZBTB32
zinc finger and BTB domain containing 32
chr14_+_77607026 0.20 ENST00000600936.1
AC007375.1
Uncharacterized protein; cDNA FLJ43210 fis, clone FEBRA2020582
chr6_+_292253 0.19 ENST00000603453.1
ENST00000605315.1
ENST00000603881.1
DUSP22
dual specificity phosphatase 22
chr1_-_11866034 0.19 ENST00000376590.3
MTHFR
methylenetetrahydrofolate reductase (NAD(P)H)
chr1_-_11865351 0.18 ENST00000413656.1
ENST00000376585.1
ENST00000423400.1
ENST00000431243.1
MTHFR
methylenetetrahydrofolate reductase (NAD(P)H)
chr1_+_104068562 0.18 ENST00000423855.2
RNPC3
RNA-binding region (RNP1, RRM) containing 3
chr3_+_4535025 0.17 ENST00000302640.8
ENST00000354582.6
ENST00000423119.2
ENST00000357086.4
ENST00000456211.2
ITPR1
inositol 1,4,5-trisphosphate receptor, type 1
chr11_-_35441524 0.17 ENST00000395750.1
ENST00000449068.1
SLC1A2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr10_+_99894380 0.16 ENST00000370584.3
R3HCC1L
R3H domain and coiled-coil containing 1-like
chr20_+_55205825 0.15 ENST00000544508.1
TFAP2C
transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
chr10_+_99894399 0.14 ENST00000298999.3
ENST00000314594.5
R3HCC1L
R3H domain and coiled-coil containing 1-like
chrX_+_152783131 0.14 ENST00000349466.2
ENST00000370186.1
ATP2B3
ATPase, Ca++ transporting, plasma membrane 3
chr17_+_37824411 0.14 ENST00000269582.2
PNMT
phenylethanolamine N-methyltransferase
chr3_+_171757346 0.14 ENST00000421757.1
ENST00000415807.2
ENST00000392699.1
FNDC3B
fibronectin type III domain containing 3B
chr12_-_75784669 0.13 ENST00000552497.1
ENST00000551829.1
ENST00000436898.1
ENST00000442339.2
CAPS2
calcyphosine 2
chr12_+_72666407 0.13 ENST00000261180.4
TRHDE
thyrotropin-releasing hormone degrading enzyme
chr1_+_182584314 0.13 ENST00000566297.1
RP11-317P15.4
RP11-317P15.4
chr6_+_150070831 0.12 ENST00000367380.5
PCMT1
protein-L-isoaspartate (D-aspartate) O-methyltransferase
chr13_-_27334879 0.11 ENST00000405846.3
GPR12
G protein-coupled receptor 12
chr5_-_151304337 0.11 ENST00000455880.2
ENST00000545569.1
ENST00000274576.4
GLRA1
glycine receptor, alpha 1
chr20_+_36888551 0.11 ENST00000418004.1
ENST00000451435.1
BPI
bactericidal/permeability-increasing protein
chr19_+_36195429 0.11 ENST00000392197.2
ZBTB32
zinc finger and BTB domain containing 32
chr2_+_232573208 0.11 ENST00000409115.3
PTMA
prothymosin, alpha
chr11_-_35440796 0.10 ENST00000278379.3
SLC1A2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr10_-_50603497 0.10 ENST00000374139.2
DRGX
dorsal root ganglia homeobox
chr7_-_129251459 0.09 ENST00000608694.1
RP11-448A19.1
RP11-448A19.1
chrX_+_54466829 0.09 ENST00000375151.4
TSR2
TSR2, 20S rRNA accumulation, homolog (S. cerevisiae)
chr2_+_233243233 0.09 ENST00000392027.2
ALPP
alkaline phosphatase, placental
chr15_+_77287426 0.09 ENST00000558012.1
ENST00000267939.5
ENST00000379595.3
PSTPIP1
proline-serine-threonine phosphatase interacting protein 1
chr1_+_228194693 0.09 ENST00000284523.1
ENST00000366753.2
WNT3A
wingless-type MMTV integration site family, member 3A
chr11_-_113345995 0.08 ENST00000355319.2
ENST00000542616.1
DRD2
dopamine receptor D2
chr12_+_72667203 0.08 ENST00000547300.1
TRHDE
thyrotropin-releasing hormone degrading enzyme
chr7_+_100464760 0.07 ENST00000200457.4
TRIP6
thyroid hormone receptor interactor 6
chr11_-_118305921 0.07 ENST00000532619.1
RP11-770J1.4
RP11-770J1.4
chr4_+_41992489 0.06 ENST00000264451.7
SLC30A9
solute carrier family 30 (zinc transporter), member 9
chr5_+_176237478 0.06 ENST00000329542.4
UNC5A
unc-5 homolog A (C. elegans)
chr5_-_179719048 0.06 ENST00000523583.1
ENST00000393360.3
ENST00000455781.1
ENST00000347470.4
ENST00000452135.2
ENST00000343111.6
MAPK9
mitogen-activated protein kinase 9
chr1_+_152943122 0.05 ENST00000328051.2
SPRR4
small proline-rich protein 4
chr2_+_241375069 0.04 ENST00000264039.2
GPC1
glypican 1
chr10_-_108924284 0.03 ENST00000344440.6
ENST00000263054.6
SORCS1
sortilin-related VPS10 domain containing receptor 1
chr20_-_13619550 0.03 ENST00000455532.1
ENST00000544472.1
ENST00000539805.1
ENST00000337743.4
TASP1
taspase, threonine aspartase, 1
chr15_+_77287715 0.03 ENST00000559161.1
PSTPIP1
proline-serine-threonine phosphatase interacting protein 1
chrX_-_118826784 0.03 ENST00000394616.4
SEPT6
septin 6
chr1_-_63782888 0.02 ENST00000436475.2
LINC00466
long intergenic non-protein coding RNA 466
chr15_-_65503801 0.02 ENST00000261883.4
CILP
cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
chr12_+_53773944 0.02 ENST00000551969.1
ENST00000327443.4
SP1
Sp1 transcription factor
chr3_+_155860751 0.01 ENST00000471742.1
KCNAB1
potassium voltage-gated channel, shaker-related subfamily, beta member 1
chr20_+_58508817 0.01 ENST00000358293.3
FAM217B
family with sequence similarity 217, member B
chr14_-_64010046 0.01 ENST00000337537.3
PPP2R5E
protein phosphatase 2, regulatory subunit B', epsilon isoform
chr3_-_48632593 0.00 ENST00000454817.1
ENST00000328333.8
COL7A1
collagen, type VII, alpha 1

Network of associatons between targets according to the STRING database.

First level regulatory network of TFAP2E

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.5 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.5 2.1 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.4 1.9 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.4 2.6 GO:1904925 negative regulation of mitochondrial membrane permeability(GO:0035795) positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.2 2.8 GO:0036486 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) neural crest cell migration involved in autonomic nervous system development(GO:1901166)
0.2 0.8 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
0.2 0.9 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
0.1 0.8 GO:2000784 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814)
0.1 1.9 GO:0051546 keratinocyte migration(GO:0051546)
0.1 1.1 GO:0042048 olfactory behavior(GO:0042048)
0.1 0.5 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 0.6 GO:0051012 microtubule sliding(GO:0051012)
0.1 0.2 GO:0097212 cadmium ion homeostasis(GO:0055073) lysosomal membrane organization(GO:0097212) negative regulation of hydrogen peroxide catabolic process(GO:2000296) regulation of oxygen metabolic process(GO:2000374)
0.1 0.2 GO:0061114 hepatocyte cell migration(GO:0002194) otic placode formation(GO:0043049) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.1 0.3 GO:1904934 chemoattraction of serotonergic neuron axon(GO:0036517) planar cell polarity pathway involved in outflow tract morphogenesis(GO:0061347) planar cell polarity pathway involved in ventricular septum morphogenesis(GO:0061348) planar cell polarity pathway involved in cardiac right atrium morphogenesis(GO:0061349) planar cell polarity pathway involved in cardiac muscle tissue morphogenesis(GO:0061350) planar cell polarity pathway involved in pericardium morphogenesis(GO:0061354) chemoattraction of axon(GO:0061642) negative regulation of cell proliferation in midbrain(GO:1904934) planar cell polarity pathway involved in midbrain dopaminergic neuron differentiation(GO:1904955)
0.1 0.7 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.1 0.2 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.1 0.3 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.1 0.3 GO:0042412 cysteine catabolic process(GO:0009093) L-cysteine catabolic process(GO:0019448) taurine biosynthetic process(GO:0042412) L-cysteine metabolic process(GO:0046439)
0.0 0.2 GO:0033274 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.0 0.5 GO:0030091 protein repair(GO:0030091)
0.0 0.1 GO:0042418 epinephrine biosynthetic process(GO:0042418)
0.0 1.0 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
0.0 0.7 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.0 0.5 GO:0070459 prolactin secretion(GO:0070459)
0.0 0.1 GO:0100012 positive regulation of cell fate specification(GO:0042660) positive regulation of dermatome development(GO:0061184) regulation of heart induction(GO:0090381) regulation of heart induction by canonical Wnt signaling pathway(GO:0100012)
0.0 0.5 GO:0030202 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0 0.2 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.3 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.4 GO:2001197 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.0 0.1 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.4 GO:0060019 radial glial cell differentiation(GO:0060019)
0.0 0.9 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 1.6 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.1 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.1 GO:0090325 regulation of locomotion involved in locomotory behavior(GO:0090325)
0.0 2.4 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.0 0.7 GO:0008284 positive regulation of cell proliferation(GO:0008284)
0.0 2.0 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.1 GO:1990034 calcium ion export from cell(GO:1990034)
0.0 0.3 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.0 0.1 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0 0.4 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.0 0.8 GO:0008333 endosome to lysosome transport(GO:0008333)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:1990584 cardiac Troponin complex(GO:1990584)
0.1 0.8 GO:0016589 NURF complex(GO:0016589)
0.1 0.7 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.1 3.4 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 0.2 GO:0097450 astrocyte end-foot(GO:0097450)
0.1 4.4 GO:0005801 cis-Golgi network(GO:0005801)
0.0 1.1 GO:0005922 connexon complex(GO:0005922)
0.0 0.4 GO:0045180 basal cortex(GO:0045180)
0.0 1.8 GO:0031526 brush border membrane(GO:0031526)
0.0 0.1 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.0 0.8 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.4 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.1 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.1 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.2 GO:0030127 COPII vesicle coat(GO:0030127)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.6 GO:0004396 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.2 3.5 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.2 0.5 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.1 0.4 GO:0030626 U12 snRNA binding(GO:0030626)
0.1 2.8 GO:0045499 chemorepellent activity(GO:0045499)
0.1 0.8 GO:0030172 troponin C binding(GO:0030172)
0.1 0.5 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.1 0.4 GO:0005110 frizzled-2 binding(GO:0005110)
0.1 3.5 GO:0043236 laminin binding(GO:0043236)
0.1 0.3 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 2.0 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.1 0.5 GO:0070728 leucine binding(GO:0070728)
0.0 0.2 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.0 0.7 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.3 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.2 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.5 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.1 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.1 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.2 GO:0046870 cadmium ion binding(GO:0046870)
0.0 1.1 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.1 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.4 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 1.6 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.1 PID RHOA PATHWAY RhoA signaling pathway
0.0 3.5 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.3 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 2.2 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 4.1 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.4 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 2.0 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 1.1 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 2.6 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 0.5 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.3 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.8 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 0.3 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.3 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.9 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.7 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction