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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for TFEC_MITF_ARNTL_BHLHE41

Z-value: 0.65

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Transcription factors associated with TFEC_MITF_ARNTL_BHLHE41

Gene Symbol Gene ID Gene Info
ENSG00000105967.11 transcription factor EC
ENSG00000187098.10 melanocyte inducing transcription factor
ENSG00000133794.13 aryl hydrocarbon receptor nuclear translocator like
ENSG00000123095.5 basic helix-loop-helix family member e41

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
BHLHE41hg19_v2_chr12_-_26278030_26278060-0.761.1e-04Click!
TFEChg19_v2_chr7_-_115799942_115799955-0.697.2e-04Click!
ARNTLhg19_v2_chr11_+_13299186_13299432-0.569.7e-03Click!
MITFhg19_v2_chr3_+_69985792_69985874-0.213.6e-01Click!

Activity profile of TFEC_MITF_ARNTL_BHLHE41 motif

Sorted Z-values of TFEC_MITF_ARNTL_BHLHE41 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_58146048 3.94 ENST00000547281.1
ENST00000546489.1
ENST00000552388.1
ENST00000540325.1
ENST00000312990.6
cyclin-dependent kinase 4
chrX_-_100662881 3.59 ENST00000218516.3
galactosidase, alpha
chr11_+_67159416 3.57 ENST00000307980.2
ENST00000544620.1
RAD9 homolog A (S. pombe)
chr12_-_58146128 3.44 ENST00000551800.1
ENST00000549606.1
ENST00000257904.6
cyclin-dependent kinase 4
chr17_-_7137857 3.37 ENST00000005340.5
dishevelled segment polarity protein 2
chr10_+_101542462 3.20 ENST00000370449.4
ENST00000370434.1
ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chr19_+_49458107 3.06 ENST00000539787.1
ENST00000345358.7
ENST00000391871.3
ENST00000415969.2
ENST00000354470.3
ENST00000506183.1
ENST00000293288.8
BCL2-associated X protein
chr22_-_36903101 2.78 ENST00000397224.4
FAD-dependent oxidoreductase domain containing 2
chr12_+_56109810 2.51 ENST00000550412.1
ENST00000257899.2
ENST00000548925.1
ENST00000549147.1
Uncharacterized protein
biogenesis of lysosomal organelles complex-1, subunit 1
chr12_+_56109926 2.31 ENST00000547076.1
biogenesis of lysosomal organelles complex-1, subunit 1
chr6_-_33385854 2.29 ENST00000488478.1
cutA divalent cation tolerance homolog (E. coli)
chr15_-_72668805 2.16 ENST00000268097.5
hexosaminidase A (alpha polypeptide)
chr15_-_72668185 2.09 ENST00000457859.2
ENST00000566304.1
ENST00000567159.1
ENST00000429918.2
hexosaminidase A (alpha polypeptide)
chr22_-_36903069 2.09 ENST00000216187.6
ENST00000423980.1
FAD-dependent oxidoreductase domain containing 2
chr16_-_28503080 2.07 ENST00000565316.1
ENST00000565778.1
ENST00000357857.9
ENST00000568558.1
ENST00000357806.7
ceroid-lipofuscinosis, neuronal 3
chr17_-_7137582 2.04 ENST00000575756.1
ENST00000575458.1
dishevelled segment polarity protein 2
chr16_-_28503357 2.02 ENST00000333496.9
ENST00000561505.1
ENST00000567963.1
ENST00000354630.5
ENST00000355477.5
ENST00000357076.5
ENST00000565688.1
ENST00000359984.7
ceroid-lipofuscinosis, neuronal 3
chr1_-_21995794 2.01 ENST00000542643.2
ENST00000374765.4
ENST00000317967.7
RAP1 GTPase activating protein
chr3_-_20227619 1.97 ENST00000425061.1
ENST00000443724.1
ENST00000421451.1
ENST00000452020.1
ENST00000417364.1
ENST00000306698.2
ENST00000419233.2
ENST00000263753.4
ENST00000383774.1
ENST00000437051.1
ENST00000412868.1
ENST00000429446.3
ENST00000442720.1
shugoshin-like 1 (S. pombe)
chr16_-_28503327 1.95 ENST00000535392.1
ENST00000395653.4
ceroid-lipofuscinosis, neuronal 3
chr14_-_21852119 1.94 ENST00000555943.1
suppressor of Ty 16 homolog (S. cerevisiae)
chr19_+_14544099 1.90 ENST00000242783.6
ENST00000586557.1
ENST00000590097.1
protein kinase N1
chr1_-_154193091 1.76 ENST00000362076.4
ENST00000350592.3
ENST00000368516.1
chromosome 1 open reading frame 43
chr8_+_103876528 1.76 ENST00000522939.1
ENST00000524007.1
HCG15011, isoform CRA_a; Protein LOC100996457
chr11_-_45307817 1.76 ENST00000020926.3
synaptotagmin XIII
chr20_-_2821271 1.72 ENST00000448755.1
ENST00000360652.2
PC-esterase domain containing 1A
chr11_+_62538775 1.71 ENST00000294168.3
ENST00000526261.1
TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
chr5_-_176730733 1.63 ENST00000504395.1
RAB24, member RAS oncogene family
chr1_-_204329013 1.62 ENST00000272203.3
ENST00000414478.1
pleckstrin homology domain containing, family A member 6
chr19_-_41256207 1.58 ENST00000598485.2
ENST00000470681.1
ENST00000339153.3
ENST00000598729.1
chromosome 19 open reading frame 54
chr16_-_1525016 1.57 ENST00000262318.8
ENST00000448525.1
chloride channel, voltage-sensitive 7
chr17_-_46688334 1.56 ENST00000239165.7
homeobox B7
chr19_+_40854559 1.54 ENST00000598962.1
ENST00000409419.1
ENST00000409587.1
ENST00000602131.1
ENST00000409735.4
ENST00000600948.1
ENST00000356508.5
ENST00000596682.1
ENST00000594908.1
phospholipase D family, member 3
chr15_+_75628232 1.54 ENST00000267935.8
ENST00000567195.1
COMM domain containing 4
chr15_+_75628394 1.52 ENST00000564815.1
ENST00000338995.6
COMM domain containing 4
chr17_+_1627834 1.50 ENST00000419248.1
ENST00000418841.1
WD repeat domain 81
chr7_+_150759634 1.49 ENST00000392826.2
ENST00000461735.1
solute carrier family 4 (anion exchanger), member 2
chr1_+_199996702 1.48 ENST00000367362.3
nuclear receptor subfamily 5, group A, member 2
chr12_+_56110247 1.48 ENST00000551926.1
biogenesis of lysosomal organelles complex-1, subunit 1
chr14_-_20929624 1.46 ENST00000398020.4
ENST00000250489.4
transmembrane protein 55B
chr15_+_75628419 1.46 ENST00000567377.1
ENST00000562789.1
ENST00000568301.1
COMM domain containing 4
chr16_+_2570340 1.44 ENST00000568263.1
ENST00000293971.6
ENST00000302956.4
ENST00000413459.3
ENST00000566706.1
ENST00000569879.1
amidohydrolase domain containing 2
chr19_+_45504688 1.43 ENST00000221452.8
ENST00000540120.1
ENST00000505236.1
v-rel avian reticuloendotheliosis viral oncogene homolog B
chr8_+_126103921 1.42 ENST00000523741.1
non-SMC element 2, MMS21 homolog (S. cerevisiae)
chr19_+_10812108 1.42 ENST00000250237.5
ENST00000592254.1
queuine tRNA-ribosyltransferase 1
chr16_+_28986085 1.41 ENST00000565975.1
ENST00000311008.11
ENST00000323081.8
ENST00000334536.8
spinster homolog 1 (Drosophila)
chr16_+_28986134 1.35 ENST00000352260.7
spinster homolog 1 (Drosophila)
chr20_-_2821756 1.34 ENST00000356872.3
ENST00000439542.1
PC-esterase domain containing 1A
chr11_-_61560053 1.34 ENST00000537328.1
transmembrane protein 258
chr17_+_62223320 1.33 ENST00000580828.1
ENST00000582965.1
small nucleolar RNA, H/ACA box 76
chr6_-_33385655 1.33 ENST00000440279.3
ENST00000607266.1
cutA divalent cation tolerance homolog (E. coli)
chr1_-_154193009 1.32 ENST00000368518.1
ENST00000368519.1
ENST00000368521.5
chromosome 1 open reading frame 43
chr5_+_133706865 1.31 ENST00000265339.2
ubiquitin-conjugating enzyme E2B
chr17_+_48450575 1.31 ENST00000338165.4
ENST00000393271.2
ENST00000511519.2
essential meiotic structure-specific endonuclease 1
chr11_+_61560348 1.30 ENST00000535723.1
ENST00000574708.1
flap structure-specific endonuclease 1
fatty acid desaturase 2
chr2_+_27309605 1.28 ENST00000260599.6
ENST00000260598.5
ENST00000429697.1
ketohexokinase (fructokinase)
chr1_-_212873267 1.26 ENST00000243440.1
basic leucine zipper transcription factor, ATF-like 3
chr10_+_69644404 1.24 ENST00000212015.6
sirtuin 1
chr22_-_42343117 1.24 ENST00000407253.3
ENST00000215980.5
centromere protein M
chr12_+_56110315 1.24 ENST00000548556.1
biogenesis of lysosomal organelles complex-1, subunit 1
chr6_-_33385823 1.24 ENST00000494751.1
ENST00000374496.3
cutA divalent cation tolerance homolog (E. coli)
chr12_-_63328817 1.22 ENST00000228705.6
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr16_-_5083917 1.22 ENST00000312251.3
ENST00000381955.3
N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
chr22_-_42342692 1.22 ENST00000404067.1
ENST00000402338.1
centromere protein M
chr12_+_54332535 1.21 ENST00000243056.3
homeobox C13
chr2_+_85981008 1.20 ENST00000306279.3
atonal homolog 8 (Drosophila)
chr19_-_10764509 1.20 ENST00000591501.1
ILF3 antisense RNA 1 (head to head)
chr17_+_78075498 1.20 ENST00000302262.3
glucosidase, alpha; acid
chr6_+_151646800 1.19 ENST00000354675.6
A kinase (PRKA) anchor protein 12
chr16_-_5083589 1.16 ENST00000563578.1
ENST00000562346.2
N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
chr1_-_23520755 1.16 ENST00000314113.3
5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled
chr16_+_5121814 1.14 ENST00000262374.5
ENST00000586840.1
ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase
chr7_+_99746514 1.11 ENST00000341942.5
ENST00000441173.1
late endosomal/lysosomal adaptor, MAPK and MTOR activator 4
chr19_+_40854363 1.08 ENST00000599685.1
ENST00000392032.2
phospholipase D family, member 3
chr2_+_46926048 1.08 ENST00000306503.5
suppressor of cytokine signaling 5
chr1_-_155211017 1.07 ENST00000536770.1
ENST00000368373.3
glucosidase, beta, acid
chr6_-_33385870 1.07 ENST00000488034.1
cutA divalent cation tolerance homolog (E. coli)
chr19_-_40854281 1.06 ENST00000392035.2
chromosome 19 open reading frame 47
chr1_+_199996733 1.06 ENST00000236914.3
nuclear receptor subfamily 5, group A, member 2
chr6_-_33385902 1.06 ENST00000374500.5
cutA divalent cation tolerance homolog (E. coli)
chr17_+_78075361 1.03 ENST00000577106.1
ENST00000390015.3
glucosidase, alpha; acid
chrY_+_2709527 1.02 ENST00000250784.8
ribosomal protein S4, Y-linked 1
chr12_-_2986107 1.00 ENST00000359843.3
ENST00000342628.2
ENST00000361953.3
forkhead box M1
chr10_+_99258625 1.00 ENST00000370664.3
ubiquitin domain containing 1
chr1_+_221051699 0.99 ENST00000366903.6
H2.0-like homeobox
chr9_-_139137648 0.97 ENST00000358701.5
quiescin Q6 sulfhydryl oxidase 2
chr2_-_47572207 0.96 ENST00000441997.1
AC073283.4
chr7_-_27196267 0.95 ENST00000242159.3
homeobox A7
chr12_-_90103077 0.94 ENST00000551310.1
ATPase, Ca++ transporting, plasma membrane 1
chr17_-_46671323 0.93 ENST00000239151.5
homeobox B5
chrY_+_15016013 0.93 ENST00000360160.4
ENST00000454054.1
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
chr2_-_133427767 0.93 ENST00000397463.2
LY6/PLAUR domain containing 1
chr22_+_31002779 0.93 ENST00000215838.3
transcobalamin II
chr2_+_176981307 0.92 ENST00000249501.4
homeobox D10
chr1_+_44440575 0.92 ENST00000532642.1
ENST00000236067.4
ENST00000471859.2
ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
chr12_-_114211444 0.91 ENST00000510694.2
ENST00000550223.1
RP11-438N16.1
chrY_+_2709906 0.91 ENST00000430575.1
ribosomal protein S4, Y-linked 1
chr19_-_36545128 0.91 ENST00000538849.1
THAP domain containing 8
chr12_+_123849462 0.91 ENST00000543072.1
hsa-mir-8072
chr16_-_2097787 0.91 ENST00000566380.1
ENST00000219066.1
nth endonuclease III-like 1 (E. coli)
chr9_-_75695323 0.90 ENST00000419959.1
aldehyde dehydrogenase 1 family, member A1
chr16_+_5083950 0.90 ENST00000588623.1
ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase
chr17_+_79935418 0.89 ENST00000306729.7
ENST00000306739.4
alveolar soft part sarcoma chromosome region, candidate 1
chr20_-_62130474 0.88 ENST00000217182.3
eukaryotic translation elongation factor 1 alpha 2
chr5_-_176730676 0.88 ENST00000393611.2
ENST00000303251.6
ENST00000303270.6
RAB24, member RAS oncogene family
chr12_+_54378923 0.87 ENST00000303460.4
homeobox C10
chr7_+_99070527 0.87 ENST00000379724.3
zinc finger protein 789
chr20_+_2821366 0.87 ENST00000453689.1
ENST00000417508.1
vacuolar protein sorting 16 homolog (S. cerevisiae)
chr15_+_69591235 0.87 ENST00000395407.2
ENST00000558684.1
progestin and adipoQ receptor family member V
chr17_+_78075324 0.86 ENST00000570803.1
glucosidase, alpha; acid
chr3_-_20227720 0.86 ENST00000412997.1
shugoshin-like 1 (S. pombe)
chr17_-_42200996 0.85 ENST00000587135.1
ENST00000225983.6
ENST00000393622.2
ENST00000588703.1
histone deacetylase 5
chr19_+_47634039 0.85 ENST00000597808.1
ENST00000413379.3
ENST00000600706.1
ENST00000540850.1
ENST00000598840.1
ENST00000600753.1
ENST00000270225.7
ENST00000392776.3
SUMO1 activating enzyme subunit 1
chr22_+_31003133 0.85 ENST00000405742.3
transcobalamin II
chr17_-_6915646 0.84 ENST00000574377.1
ENST00000399541.2
ENST00000399540.2
ENST00000575727.1
ENST00000573939.1
Uncharacterized protein
chr7_+_100271355 0.84 ENST00000436220.1
ENST00000424361.1
guanine nucleotide binding protein (G protein), beta polypeptide 2
chr2_+_228189867 0.84 ENST00000423098.1
ENST00000304593.9
mitochondrial fission factor
chr3_+_19988736 0.84 ENST00000443878.1
RAB5A, member RAS oncogene family
chr19_+_8386371 0.83 ENST00000600659.2
ribosomal protein S28
chr1_-_155211065 0.83 ENST00000427500.3
glucosidase, beta, acid
chr2_-_47572105 0.82 ENST00000419035.1
ENST00000448713.1
ENST00000450550.1
ENST00000413185.2
AC073283.4
chr17_+_46970134 0.82 ENST00000503641.1
ENST00000514808.1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
chr2_+_240323439 0.82 ENST00000428471.1
ENST00000413029.1
Uncharacterized protein
chr19_-_5340730 0.81 ENST00000372412.4
ENST00000357368.4
ENST00000262963.6
ENST00000348075.2
ENST00000353284.2
protein tyrosine phosphatase, receptor type, S
chr1_-_11865982 0.81 ENST00000418034.1
methylenetetrahydrofolate reductase (NAD(P)H)
chrX_-_34675391 0.81 ENST00000275954.3
transmembrane protein 47
chr4_-_100871506 0.80 ENST00000296417.5
H2A histone family, member Z
chr19_+_41305330 0.80 ENST00000593972.1
egl-9 family hypoxia-inducible factor 2
chr19_-_40854417 0.80 ENST00000582006.1
ENST00000582783.1
chromosome 19 open reading frame 47
chr12_-_90102594 0.77 ENST00000428670.3
ATPase, Ca++ transporting, plasma membrane 1
chr3_-_126076264 0.76 ENST00000296233.3
Kruppel-like factor 15
chr7_-_47622156 0.76 ENST00000457718.1
tensin 3
chr22_+_35776828 0.75 ENST00000216117.8
heme oxygenase (decycling) 1
chr7_+_150758304 0.75 ENST00000482950.1
ENST00000463414.1
ENST00000310317.5
solute carrier family 4 (anion exchanger), member 2
chr2_+_176972000 0.75 ENST00000249504.5
homeobox D11
chr17_+_79935464 0.74 ENST00000581647.1
ENST00000580534.1
ENST00000579684.1
alveolar soft part sarcoma chromosome region, candidate 1
chrX_+_72783026 0.74 ENST00000373504.6
ENST00000373502.5
cysteine-rich hydrophobic domain 1
chr12_+_53645870 0.74 ENST00000329548.4
major facilitator superfamily domain containing 5
chr5_+_133707252 0.73 ENST00000506787.1
ENST00000507277.1
ubiquitin-conjugating enzyme E2B
chr20_+_18118703 0.73 ENST00000464792.1
CSRP2 binding protein
chr16_+_83986827 0.72 ENST00000393306.1
ENST00000565123.1
oxidative stress induced growth inhibitor 1
chr2_-_220083692 0.72 ENST00000265316.3
ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr2_-_220083671 0.72 ENST00000439002.2
ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr10_-_99258135 0.72 ENST00000327238.10
ENST00000327277.7
ENST00000355839.6
ENST00000437002.1
ENST00000422685.1
MMS19 nucleotide excision repair homolog (S. cerevisiae)
chr7_+_100271446 0.72 ENST00000419828.1
ENST00000427895.1
guanine nucleotide binding protein (G protein), beta polypeptide 2
chr22_-_39268308 0.71 ENST00000407418.3
chromobox homolog 6
chr15_+_91260552 0.71 ENST00000355112.3
ENST00000560509.1
Bloom syndrome, RecQ helicase-like
chr19_+_32836499 0.71 ENST00000311921.4
ENST00000544431.1
ENST00000355898.5
zinc finger protein 507
chr6_-_109703663 0.70 ENST00000368961.5
CD164 molecule, sialomucin
chr17_-_18266660 0.70 ENST00000582653.1
ENST00000352886.6
serine hydroxymethyltransferase 1 (soluble)
chr1_+_11866207 0.69 ENST00000312413.6
ENST00000346436.6
chloride channel, voltage-sensitive 6
chr17_-_79791118 0.68 ENST00000576431.1
ENST00000575061.1
ENST00000455127.2
ENST00000572645.1
ENST00000538396.1
ENST00000573478.1
family with sequence similarity 195, member B
chr17_-_18218270 0.68 ENST00000321105.5
topoisomerase (DNA) III alpha
chr16_-_70323422 0.68 ENST00000261772.8
alanyl-tRNA synthetase
chr8_-_95274536 0.68 ENST00000297596.2
ENST00000396194.2
GTP binding protein overexpressed in skeletal muscle
chr12_+_85673868 0.68 ENST00000316824.3
ALX homeobox 1
chr16_+_770975 0.67 ENST00000569529.1
ENST00000564000.1
ENST00000219535.3
family with sequence similarity 173, member A
chrX_+_153627231 0.66 ENST00000406022.2
ribosomal protein L10
chrX_+_102631248 0.66 ENST00000361298.4
ENST00000372645.3
ENST00000372635.1
nerve growth factor receptor (TNFRSF16) associated protein 1
chr12_+_51632638 0.66 ENST00000549732.2
DAZ associated protein 2
chr16_+_2570431 0.66 ENST00000563556.1
amidohydrolase domain containing 2
chr4_-_164253738 0.66 ENST00000509586.1
ENST00000504391.1
ENST00000512819.1
neuropeptide Y receptor Y1
chr11_-_71814422 0.65 ENST00000278671.5
late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
chr5_-_172198190 0.64 ENST00000239223.3
dual specificity phosphatase 1
chr15_-_83316254 0.64 ENST00000567678.1
ENST00000450751.2
cytoplasmic polyadenylation element binding protein 1
chr7_+_4815238 0.64 ENST00000348624.4
ENST00000401897.1
adaptor-related protein complex 5, zeta 1 subunit
chr17_-_42200958 0.64 ENST00000336057.5
histone deacetylase 5
chr7_-_99699538 0.63 ENST00000343023.6
ENST00000303887.5
minichromosome maintenance complex component 7
chr10_-_32217717 0.63 ENST00000396144.4
ENST00000375245.4
ENST00000344936.2
ENST00000375250.5
Rho GTPase activating protein 12
chr12_+_54378849 0.63 ENST00000515593.1
homeobox C10
chrY_+_15016725 0.63 ENST00000336079.3
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
chr5_+_41904431 0.63 ENST00000381647.2
chromosome 5 open reading frame 51
chr11_+_67776012 0.62 ENST00000539229.1
aldehyde dehydrogenase 3 family, member B1
chr2_-_120980939 0.62 ENST00000426077.2
transmembrane protein 185B
chr12_+_90102729 0.62 ENST00000605386.1
long intergenic non-protein coding RNA 936
chrX_+_102883887 0.62 ENST00000372625.3
ENST00000372624.3
transcription elongation factor A (SII)-like 1
chrX_-_15872914 0.62 ENST00000380291.1
ENST00000545766.1
ENST00000421527.2
ENST00000329235.2
adaptor-related protein complex 1, sigma 2 subunit
chr6_+_36562132 0.60 ENST00000373715.6
ENST00000339436.7
serine/arginine-rich splicing factor 3
chr19_-_15236470 0.60 ENST00000533747.1
ENST00000598709.1
ENST00000534378.1
ilvB (bacterial acetolactate synthase)-like
chr19_-_49016847 0.60 ENST00000598924.1
CTC-273B12.10
chr17_-_40346477 0.60 ENST00000593209.1
ENST00000587427.1
ENST00000588352.1
ENST00000414034.3
ENST00000590249.1
GH3 domain containing
chr6_+_151561085 0.60 ENST00000402676.2
A kinase (PRKA) anchor protein 12
chr1_-_68962782 0.60 ENST00000456315.2
DEP domain containing 1
chr1_-_154909329 0.60 ENST00000368467.3
phosphomevalonate kinase
chr1_+_17248418 0.60 ENST00000375541.5
ciliary rootlet coiled-coil, rootletin
chr17_-_18218237 0.59 ENST00000542570.1
topoisomerase (DNA) III alpha
chr4_-_47465666 0.58 ENST00000381571.4
COMM domain containing 8
chr19_+_41305406 0.58 ENST00000406058.2
ENST00000593726.1
egl-9 family hypoxia-inducible factor 2
chr2_-_40006357 0.58 ENST00000505747.1
THUMP domain containing 2
chr20_+_2821340 0.58 ENST00000380445.3
ENST00000380469.3
vacuolar protein sorting 16 homolog (S. cerevisiae)
chr22_-_39268192 0.57 ENST00000216083.6
chromobox homolog 6
chr17_-_26684473 0.57 ENST00000540200.1
polymerase (DNA-directed), delta interacting protein 2
chr8_-_126104055 0.57 ENST00000318410.7
KIAA0196
chr14_-_54955721 0.56 ENST00000554908.1
glia maturation factor, beta
chr11_-_61560254 0.56 ENST00000543510.1
transmembrane protein 258
chr1_-_68962805 0.56 ENST00000370966.5
DEP domain containing 1
chr16_-_2168079 0.56 ENST00000488185.2
polycystic kidney disease 1 (autosomal dominant)
chr17_+_40688190 0.56 ENST00000225927.2
N-acetylglucosaminidase, alpha
chr14_-_20922960 0.56 ENST00000553640.1
ENST00000488532.2
O-sialoglycoprotein endopeptidase
chr22_-_51017084 0.55 ENST00000360719.2
ENST00000457250.1
ENST00000440709.1
carnitine palmitoyltransferase 1B (muscle)

Network of associatons between targets according to the STRING database.

First level regulatory network of TFEC_MITF_ARNTL_BHLHE41

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 6.0 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
1.4 5.4 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
1.1 3.2 GO:0050787 antibiotic metabolic process(GO:0016999) detoxification of mercury ion(GO:0050787)
1.0 3.1 GO:0043181 vacuolar sequestering(GO:0043181)
1.0 3.1 GO:0048597 B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597) positive regulation of apoptotic DNA fragmentation(GO:1902512)
0.7 2.0 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.7 2.0 GO:1903697 negative regulation of microvillus assembly(GO:1903697)
0.6 5.1 GO:1904637 response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
0.5 3.6 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.5 5.6 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.5 7.6 GO:0060155 platelet dense granule organization(GO:0060155)
0.4 1.2 GO:1990619 histone H3-K9 deacetylation(GO:1990619)
0.4 1.2 GO:0070407 oxidation-dependent protein catabolic process(GO:0070407)
0.4 1.5 GO:1904482 response to tetrahydrofolate(GO:1904481) cellular response to tetrahydrofolate(GO:1904482)
0.4 0.8 GO:0032764 negative regulation of mast cell cytokine production(GO:0032764)
0.4 2.2 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.4 2.5 GO:0061113 pancreas morphogenesis(GO:0061113)
0.3 1.3 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.3 1.3 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.3 1.9 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.3 1.4 GO:0034184 positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.3 2.5 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.3 0.8 GO:0031662 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662) response to DDT(GO:0046680) histone H3-S10 phosphorylation involved in chromosome condensation(GO:2000775)
0.3 0.8 GO:0034164 negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.3 1.1 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.3 2.1 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.3 1.0 GO:0042144 vacuole fusion, non-autophagic(GO:0042144)
0.2 1.0 GO:0090299 regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.2 0.7 GO:0002940 tRNA N2-guanine methylation(GO:0002940)
0.2 1.5 GO:1900063 regulation of peroxisome organization(GO:1900063)
0.2 0.2 GO:2000506 negative regulation of energy homeostasis(GO:2000506)
0.2 0.7 GO:1902568 regulation of eosinophil degranulation(GO:0043309) positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.2 5.0 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.2 0.7 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.2 0.7 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.2 2.8 GO:0015889 cobalamin transport(GO:0015889)
0.2 0.6 GO:0006258 UDP-glucose catabolic process(GO:0006258)
0.2 0.6 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.2 1.2 GO:0060620 regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.2 2.7 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.2 1.7 GO:1990034 cellular response to corticosterone stimulus(GO:0071386) calcium ion export from cell(GO:1990034)
0.2 0.6 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
0.2 0.5 GO:0061580 colon epithelial cell migration(GO:0061580)
0.2 0.7 GO:0072287 metanephric distal tubule morphogenesis(GO:0072287)
0.2 2.4 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.1 0.6 GO:0032053 ciliary basal body organization(GO:0032053) positive regulation of protein localization to cilium(GO:1903566)
0.1 0.4 GO:0010259 multicellular organism aging(GO:0010259)
0.1 0.4 GO:1901207 regulation of heart looping(GO:1901207)
0.1 0.4 GO:0000961 negative regulation of mitochondrial RNA catabolic process(GO:0000961)
0.1 0.1 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.1 1.7 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 0.5 GO:0060535 trachea cartilage morphogenesis(GO:0060535)
0.1 2.6 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.1 1.7 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.1 0.7 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.1 1.5 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.1 1.1 GO:0014827 intestine smooth muscle contraction(GO:0014827)
0.1 0.3 GO:1902463 protein localization to cell leading edge(GO:1902463)
0.1 0.4 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
0.1 0.4 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.1 0.4 GO:0005985 sucrose metabolic process(GO:0005985)
0.1 0.5 GO:0033274 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.1 0.8 GO:0090238 positive regulation of arachidonic acid secretion(GO:0090238)
0.1 0.3 GO:1903564 regulation of protein localization to cilium(GO:1903564) negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.1 0.3 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.1 0.5 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.1 1.8 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.1 0.4 GO:0060168 positive regulation of adenosine receptor signaling pathway(GO:0060168) regulation of G-protein coupled receptor internalization(GO:1904020)
0.1 0.7 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.1 0.8 GO:0021546 rhombomere development(GO:0021546)
0.1 1.0 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.1 0.3 GO:0015993 L-ascorbic acid transport(GO:0015882) molecular hydrogen transport(GO:0015993) transepithelial L-ascorbic acid transport(GO:0070904)
0.1 0.8 GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.1 0.3 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.1 0.3 GO:0045925 positive regulation of female receptivity(GO:0045925)
0.1 0.8 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.1 1.8 GO:0015886 heme transport(GO:0015886)
0.1 0.4 GO:0019303 D-ribose catabolic process(GO:0019303)
0.1 0.3 GO:0019516 lactate oxidation(GO:0019516)
0.1 0.7 GO:0010587 miRNA catabolic process(GO:0010587)
0.1 0.2 GO:1902990 mitotic telomere maintenance via semi-conservative replication(GO:1902990)
0.1 0.7 GO:0019471 4-hydroxyproline metabolic process(GO:0019471)
0.1 1.4 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.1 0.1 GO:0072003 kidney rudiment formation(GO:0072003)
0.1 0.3 GO:0046452 dihydrofolate metabolic process(GO:0046452)
0.1 0.4 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.1 1.1 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.1 0.4 GO:0098502 DNA dephosphorylation(GO:0098502)
0.1 0.8 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1 1.2 GO:0035878 nail development(GO:0035878)
0.1 0.3 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.1 0.4 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.1 0.4 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.1 0.4 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.1 0.6 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.1 1.0 GO:2000781 positive regulation of double-strand break repair(GO:2000781)
0.1 0.2 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.1 3.0 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.1 0.2 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.1 0.2 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.1 2.8 GO:0097502 mannosylation(GO:0097502)
0.1 0.6 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.1 1.4 GO:0002115 store-operated calcium entry(GO:0002115)
0.1 0.2 GO:0019348 dolichol metabolic process(GO:0019348)
0.1 0.2 GO:1902269 positive regulation of polyamine transmembrane transport(GO:1902269)
0.1 1.6 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.1 0.5 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.1 0.1 GO:0071400 cellular response to oleic acid(GO:0071400)
0.1 0.3 GO:0019242 methylglyoxal biosynthetic process(GO:0019242)
0.1 0.6 GO:0046185 aldehyde catabolic process(GO:0046185)
0.1 0.2 GO:0016340 calcium-dependent cell-matrix adhesion(GO:0016340)
0.1 1.3 GO:0006265 DNA topological change(GO:0006265)
0.1 1.5 GO:0090051 negative regulation of cell migration involved in sprouting angiogenesis(GO:0090051)
0.1 1.6 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.1 0.3 GO:0014050 negative regulation of glutamate secretion(GO:0014050)
0.1 0.8 GO:0048262 determination of dorsal/ventral asymmetry(GO:0048262)
0.1 0.8 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.1 0.2 GO:0006147 guanine catabolic process(GO:0006147)
0.1 0.3 GO:0014057 positive regulation of acetylcholine secretion, neurotransmission(GO:0014057)
0.1 1.1 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.1 0.2 GO:0006114 glycerol biosynthetic process(GO:0006114)
0.1 0.2 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
0.1 0.5 GO:0021769 orbitofrontal cortex development(GO:0021769)
0.1 0.5 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.0 0.1 GO:1990828 response to putrescine(GO:1904585) cellular response to putrescine(GO:1904586) hepatocyte dedifferentiation(GO:1990828)
0.0 0.4 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.6 GO:0015691 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.0 0.4 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 0.1 GO:0035281 pre-miRNA export from nucleus(GO:0035281)
0.0 0.1 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.0 0.1 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.0 0.3 GO:0045900 negative regulation of translational elongation(GO:0045900)
0.0 0.1 GO:0090149 mitochondrial membrane fission(GO:0090149)
0.0 0.1 GO:0007343 egg activation(GO:0007343)
0.0 0.1 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
0.0 0.6 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.0 1.2 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.0 0.1 GO:0051182 coenzyme transport(GO:0051182)
0.0 1.0 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.1 GO:0000921 septin ring assembly(GO:0000921) septin ring organization(GO:0031106)
0.0 0.3 GO:0044565 dendritic cell proliferation(GO:0044565)
0.0 0.3 GO:0051344 regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.0 0.1 GO:0002879 leukocyte chemotaxis involved in inflammatory response(GO:0002232) positive regulation of acute inflammatory response to non-antigenic stimulus(GO:0002879)
0.0 1.5 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.0 0.1 GO:1901857 positive regulation of cellular respiration(GO:1901857)
0.0 0.2 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.2 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902)
0.0 0.3 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.0 0.2 GO:0044111 development involved in symbiotic interaction(GO:0044111)
0.0 1.1 GO:0051770 positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770)
0.0 3.3 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.2 GO:0021993 initiation of neural tube closure(GO:0021993)
0.0 0.3 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 2.7 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.0 0.9 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.0 0.4 GO:0071569 protein ufmylation(GO:0071569)
0.0 0.1 GO:0061687 detoxification of inorganic compound(GO:0061687)
0.0 0.3 GO:2000035 regulation of stem cell division(GO:2000035)
0.0 0.1 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.1 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.0 0.7 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.4 GO:1902074 response to salt(GO:1902074)
0.0 0.3 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.2 GO:0046203 spermidine catabolic process(GO:0046203)
0.0 0.1 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.0 1.0 GO:1905144 acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.0 0.1 GO:0048250 mitochondrial iron ion transport(GO:0048250)
0.0 0.1 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.0 0.1 GO:0003335 corneocyte development(GO:0003335)
0.0 0.1 GO:0045588 positive regulation of gamma-delta T cell differentiation(GO:0045588) positive regulation of gamma-delta T cell activation(GO:0046645)
0.0 0.3 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.1 GO:0072237 proximal convoluted tubule development(GO:0072019) metanephric proximal convoluted tubule development(GO:0072229) metanephric proximal tubule development(GO:0072237)
0.0 0.1 GO:0071163 DNA replication preinitiation complex assembly(GO:0071163)
0.0 0.0 GO:0001658 branching involved in ureteric bud morphogenesis(GO:0001658)
0.0 0.1 GO:1903028 positive regulation of opsonization(GO:1903028)
0.0 2.1 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.0 0.3 GO:1901142 insulin metabolic process(GO:1901142)
0.0 0.3 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.0 0.2 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
0.0 0.1 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.0 0.3 GO:0002759 regulation of antimicrobial humoral response(GO:0002759)
0.0 0.2 GO:0006045 N-acetylglucosamine biosynthetic process(GO:0006045) glucosamine-containing compound biosynthetic process(GO:1901073)
0.0 0.8 GO:0072112 renal filtration cell differentiation(GO:0061318) glomerular visceral epithelial cell differentiation(GO:0072112)
0.0 0.0 GO:0070827 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960) chromatin maintenance(GO:0070827)
0.0 0.3 GO:0050957 equilibrioception(GO:0050957)
0.0 0.7 GO:0001502 cartilage condensation(GO:0001502)
0.0 0.5 GO:0042474 middle ear morphogenesis(GO:0042474)
0.0 0.1 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.0 0.6 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.5 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.0 0.1 GO:2000174 regulation of pro-T cell differentiation(GO:2000174) positive regulation of pro-T cell differentiation(GO:2000176)
0.0 0.3 GO:1900377 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.0 0.5 GO:0009162 deoxyribonucleoside monophosphate metabolic process(GO:0009162)
0.0 0.1 GO:0014029 neural crest formation(GO:0014029)
0.0 0.8 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.1 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.0 2.3 GO:0006400 tRNA modification(GO:0006400)
0.0 0.2 GO:0097033 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.5 GO:0071420 cellular response to histamine(GO:0071420)
0.0 1.2 GO:0097421 liver regeneration(GO:0097421)
0.0 0.1 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.0 3.1 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0 0.1 GO:0006500 N-terminal protein palmitoylation(GO:0006500)
0.0 0.5 GO:0021554 optic nerve development(GO:0021554)
0.0 0.1 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
0.0 1.0 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.2 GO:0097461 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.0 0.1 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.1 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.0 1.2 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.3 GO:0001522 pseudouridine synthesis(GO:0001522)
0.0 0.1 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.2 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.2 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.0 0.6 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.3 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.5 GO:0006853 carnitine shuttle(GO:0006853)
0.0 0.1 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
0.0 0.6 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.2 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.0 0.1 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.0 0.1 GO:0032380 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0 0.1 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.0 0.2 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 0.0 GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
0.0 0.2 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.2 GO:0006538 glutamate catabolic process(GO:0006538)
0.0 0.1 GO:0035698 CD8-positive, alpha-beta T cell extravasation(GO:0035697) CD8-positive, alpha-beta cytotoxic T cell extravasation(GO:0035698) T cell extravasation(GO:0072683) regulation of T cell extravasation(GO:2000407) regulation of CD8-positive, alpha-beta T cell extravasation(GO:2000449) regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation(GO:2000452)
0.0 0.3 GO:0070914 UV-damage excision repair(GO:0070914)
0.0 1.7 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.1 GO:0006043 glucosamine catabolic process(GO:0006043)
0.0 0.1 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.0 0.6 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0 0.1 GO:0021898 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) cerebral cortex GABAergic interneuron fate commitment(GO:0021893) commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
0.0 0.1 GO:1903232 melanosome assembly(GO:1903232)
0.0 0.1 GO:0043335 protein unfolding(GO:0043335)
0.0 0.2 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.0 0.1 GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.0 0.5 GO:0032211 negative regulation of telomere maintenance via telomerase(GO:0032211)
0.0 0.0 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.0 0.6 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0 0.1 GO:0051106 positive regulation of DNA ligation(GO:0051106)
0.0 0.3 GO:0098792 xenophagy(GO:0098792)
0.0 0.1 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0 0.1 GO:0098876 vesicle-mediated transport to the plasma membrane(GO:0098876)
0.0 0.1 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0 0.5 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.2 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 0.2 GO:0032264 IMP salvage(GO:0032264)
0.0 0.1 GO:1902044 regulation of Fas signaling pathway(GO:1902044)
0.0 0.1 GO:0098886 modification of dendritic spine(GO:0098886)
0.0 0.1 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.0 0.0 GO:0070346 positive regulation of fat cell proliferation(GO:0070346)
0.0 0.5 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.2 GO:1903393 positive regulation of focal adhesion assembly(GO:0051894) positive regulation of adherens junction organization(GO:1903393)
0.0 0.3 GO:0018126 protein hydroxylation(GO:0018126)
0.0 0.2 GO:0099601 regulation of neurotransmitter receptor activity(GO:0099601)
0.0 0.1 GO:0015866 ADP transport(GO:0015866)
0.0 0.1 GO:0042908 xenobiotic transport(GO:0042908)
0.0 0.2 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0 0.1 GO:0072502 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.1 GO:0010609 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609)
0.0 0.1 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0 0.2 GO:0030043 actin filament fragmentation(GO:0030043)
0.0 0.2 GO:0015816 glycine transport(GO:0015816)
0.0 0.1 GO:1905146 lysosomal protein catabolic process(GO:1905146)
0.0 0.1 GO:0044789 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.0 0.3 GO:1903206 negative regulation of hydrogen peroxide-induced cell death(GO:1903206)
0.0 0.3 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.0 GO:0061004 pattern specification involved in kidney development(GO:0061004) renal system pattern specification(GO:0072048) pattern specification involved in metanephros development(GO:0072268)
0.0 0.1 GO:0086053 AV node cell to bundle of His cell communication by electrical coupling(GO:0086053)
0.0 0.1 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.2 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.9 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.1 GO:0015811 L-cystine transport(GO:0015811)
0.0 0.5 GO:0071173 mitotic spindle assembly checkpoint(GO:0007094) spindle assembly checkpoint(GO:0071173)
0.0 0.5 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.2 GO:0006477 protein sulfation(GO:0006477)
0.0 0.2 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.0 GO:0051924 regulation of calcium ion transport(GO:0051924)
0.0 0.1 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.3 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.2 GO:0007379 segment specification(GO:0007379)
0.0 0.1 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.3 GO:0090140 regulation of mitochondrial fission(GO:0090140)
0.0 0.1 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 0.4 GO:0031648 protein destabilization(GO:0031648)
0.0 0.2 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.0 GO:0043438 acetoacetic acid metabolic process(GO:0043438)
0.0 0.1 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.3 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.2 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.0 0.1 GO:0070072 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.1 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.0 0.1 GO:0036066 protein O-linked fucosylation(GO:0036066)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0035101 FACT complex(GO:0035101)
0.6 4.8 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.3 3.1 GO:0030896 checkpoint clamp complex(GO:0030896)
0.2 1.3 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.2 3.1 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.2 2.6 GO:0046581 intercellular canaliculus(GO:0046581)
0.2 2.0 GO:0033503 HULC complex(GO:0033503)
0.2 1.2 GO:0071817 MMXD complex(GO:0071817)
0.2 2.5 GO:0071986 Ragulator complex(GO:0071986)
0.2 1.2 GO:0033553 rDNA heterochromatin(GO:0033553)
0.2 5.9 GO:0031083 BLOC-1 complex(GO:0031083)
0.2 0.9 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.2 0.8 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.2 1.4 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.1 0.7 GO:0002133 polycystin complex(GO:0002133)
0.1 1.1 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.1 2.1 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 0.5 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.1 0.4 GO:0005960 glycine cleavage complex(GO:0005960)
0.1 1.4 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.1 1.6 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.1 1.4 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 0.8 GO:0001740 Barr body(GO:0001740)
0.1 0.3 GO:0033597 mitotic checkpoint complex(GO:0033597) bub1-bub3 complex(GO:1990298)
0.1 0.4 GO:0070288 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.1 16.4 GO:0043202 lysosomal lumen(GO:0043202)
0.1 1.8 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 0.2 GO:0070557 PCNA-p21 complex(GO:0070557)
0.1 0.7 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 0.3 GO:0031084 BLOC-2 complex(GO:0031084)
0.1 1.9 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 0.3 GO:1990742 microvesicle(GO:1990742)
0.1 0.4 GO:1990246 uniplex complex(GO:1990246)
0.1 0.9 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1 0.3 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 5.3 GO:0016235 aggresome(GO:0016235)
0.1 1.0 GO:0030914 STAGA complex(GO:0030914)
0.0 0.2 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.0 0.4 GO:0097452 GAIT complex(GO:0097452)
0.0 0.2 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0 0.6 GO:0042555 MCM complex(GO:0042555)
0.0 0.1 GO:0000243 commitment complex(GO:0000243)
0.0 0.3 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 6.2 GO:0005901 caveola(GO:0005901)
0.0 0.7 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.0 0.6 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.3 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.2 GO:0033186 CAF-1 complex(GO:0033186)
0.0 0.2 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.3 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.4 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.2 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0 0.3 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.8 GO:0000800 lateral element(GO:0000800)
0.0 0.1 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.0 2.0 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.5 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.3 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.1 GO:0031082 BLOC complex(GO:0031082)
0.0 0.2 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.3 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.2 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.1 GO:0045273 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.8 GO:0071011 precatalytic spliceosome(GO:0071011)
0.0 0.2 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 1.9 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.5 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
0.0 0.2 GO:0031010 ISWI-type complex(GO:0031010)
0.0 0.4 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.5 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.2 GO:0005827 polar microtubule(GO:0005827)
0.0 0.7 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.1 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.2 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.2 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.6 GO:0044291 cell-cell contact zone(GO:0044291)
0.0 0.6 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.5 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.5 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.3 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.4 GO:0005685 U1 snRNP(GO:0005685)
0.0 0.1 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.1 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.4 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.1 GO:0044611 nuclear pore inner ring(GO:0044611)
0.0 1.5 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 1.8 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.2 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.0 0.1 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.0 0.1 GO:0090661 box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.0 0.1 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 1.8 GO:0000784 nuclear chromosome, telomeric region(GO:0000784)
0.0 0.5 GO:0051233 spindle midzone(GO:0051233)
0.0 0.1 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.0 0.8 GO:0032592 integral component of mitochondrial membrane(GO:0032592)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.1 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.6 3.6 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.5 3.6 GO:0016936 galactoside binding(GO:0016936)
0.5 3.0 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.5 1.4 GO:0015439 heme-transporting ATPase activity(GO:0015439)
0.5 4.3 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.4 1.2 GO:0046969 histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969)
0.4 1.2 GO:0070362 mitochondrial light strand promoter anti-sense binding(GO:0070361) mitochondrial heavy strand promoter anti-sense binding(GO:0070362) mitochondrial heavy strand promoter sense binding(GO:0070364)
0.4 1.9 GO:0004348 glucosylceramidase activity(GO:0004348)
0.4 1.1 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.3 1.9 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.3 1.5 GO:0070905 serine binding(GO:0070905)
0.3 1.2 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.3 0.9 GO:0019948 SUMO activating enzyme activity(GO:0019948)
0.3 1.4 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.3 3.1 GO:0051434 BH3 domain binding(GO:0051434)
0.3 1.0 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.2 1.5 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.2 3.4 GO:0004630 phospholipase D activity(GO:0004630)
0.2 0.9 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.2 0.7 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.2 0.9 GO:0008534 oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534)
0.2 0.6 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.2 2.7 GO:0031419 cobalamin binding(GO:0031419)
0.2 1.0 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.2 0.8 GO:0001601 peptide YY receptor activity(GO:0001601)
0.2 0.6 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.2 0.6 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
0.2 2.9 GO:0015929 hexosaminidase activity(GO:0015929)
0.2 0.7 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.2 3.2 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.2 0.5 GO:0008859 exoribonuclease II activity(GO:0008859)
0.2 1.5 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.2 1.5 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.2 0.9 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.1 1.8 GO:0019826 oxygen sensor activity(GO:0019826)
0.1 1.3 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.1 0.4 GO:0048244 phytanoyl-CoA dioxygenase activity(GO:0048244)
0.1 0.2 GO:0030337 DNA polymerase processivity factor activity(GO:0030337)
0.1 0.7 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.1 0.8 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.1 0.7 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.1 0.7 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 1.2 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.1 0.5 GO:0005471 ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
0.1 0.6 GO:0019770 IgG receptor activity(GO:0019770)
0.1 1.5 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.1 2.2 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 1.3 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.1 5.4 GO:0005109 frizzled binding(GO:0005109)
0.1 2.7 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 0.4 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.1 0.5 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.1 0.3 GO:0004844 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.1 0.4 GO:0004967 glucagon receptor activity(GO:0004967)
0.1 0.9 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.1 0.3 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.1 0.4 GO:0031685 adenosine receptor binding(GO:0031685)
0.1 0.3 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.1 0.3 GO:0016250 N-sulfoglucosamine sulfohydrolase activity(GO:0016250) hydrolase activity, acting on acid sulfur-nitrogen bonds(GO:0016826)
0.1 0.9 GO:1990446 U1 snRNP binding(GO:1990446)
0.1 0.4 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.1 0.4 GO:0072590 N-acetyl-L-aspartate-L-glutamate ligase activity(GO:0072590)
0.1 0.7 GO:0000403 Y-form DNA binding(GO:0000403) four-way junction helicase activity(GO:0009378)
0.1 0.5 GO:0004945 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.1 3.9 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 0.3 GO:0016898 D-lactate dehydrogenase (cytochrome) activity(GO:0004458) oxidoreductase activity, acting on the CH-OH group of donors, cytochrome as acceptor(GO:0016898)
0.1 0.5 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 0.6 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.1 2.4 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 0.8 GO:0048039 ubiquinone binding(GO:0048039)
0.1 2.8 GO:0000030 mannosyltransferase activity(GO:0000030)
0.1 0.3 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.1 0.3 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.1 0.7 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 1.7 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 0.6 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.1 0.7 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.1 0.2 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.1 1.2 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 0.9 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.1 6.8 GO:0005507 copper ion binding(GO:0005507)
0.1 0.2 GO:0015633 zinc transporting ATPase activity(GO:0015633)
0.1 0.3 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 0.3 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.1 0.2 GO:0034511 U3 snoRNA binding(GO:0034511)
0.1 0.4 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.1 0.2 GO:0034038 deoxyhypusine synthase activity(GO:0034038)
0.1 0.8 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.1 0.3 GO:0004347 glucose-6-phosphate isomerase activity(GO:0004347)
0.1 0.5 GO:0070087 chromo shadow domain binding(GO:0070087)
0.1 0.8 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.1 0.2 GO:0008892 guanine deaminase activity(GO:0008892)
0.0 0.0 GO:0038181 bile acid receptor activity(GO:0038181)
0.0 0.2 GO:0051734 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0 0.1 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.0 1.0 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.2 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.0 0.3 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.4 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.1 GO:0090631 pre-miRNA transporter activity(GO:0090631)
0.0 0.3 GO:0004127 cytidylate kinase activity(GO:0004127)
0.0 0.5 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.7 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 1.2 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.1 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 1.4 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.1 GO:0008969 phosphohistidine phosphatase activity(GO:0008969)
0.0 4.7 GO:0050660 flavin adenine dinucleotide binding(GO:0050660)
0.0 0.7 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.3 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.0 0.1 GO:0036033 mediator complex binding(GO:0036033)
0.0 0.1 GO:0031626 beta-endorphin binding(GO:0031626)
0.0 1.0 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.2 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.2 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0 0.1 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 0.3 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.3 GO:0019238 cyclohydrolase activity(GO:0019238)
0.0 0.1 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.0 0.3 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.3 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 0.2 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.1 GO:0003883 CTP synthase activity(GO:0003883)
0.0 1.7 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.8 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.1 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
0.0 0.3 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.2 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.2 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.0 0.1 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.9 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 1.1 GO:0031491 nucleosome binding(GO:0031491)
0.0 2.7 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 0.7 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.3 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.1 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.0 0.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 1.8 GO:0019843 rRNA binding(GO:0019843)
0.0 0.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.1 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.3 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.2 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.0 0.1 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.0 4.0 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.2 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.1 GO:0001602 pancreatic polypeptide receptor activity(GO:0001602)
0.0 0.2 GO:0004985 opioid receptor activity(GO:0004985)
0.0 1.2 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.1 GO:0052839 inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.0 0.6 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.2 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.1 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.0 0.4 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.1 GO:0005119 smoothened binding(GO:0005119)
0.0 0.3 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.2 GO:0099602 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 1.1 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.2 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.4 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.1 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.0 0.4 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.8 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.2 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.1 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.0 GO:0010309 acireductone dioxygenase [iron(II)-requiring] activity(GO:0010309)
0.0 0.6 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.3 GO:0005542 folic acid binding(GO:0005542)
0.0 0.1 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.3 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.2 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.8 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.5 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.2 GO:0019534 toxin transporter activity(GO:0019534)
0.0 1.6 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.2 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.1 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.1 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.0 0.1 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.0 0.1 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.1 GO:0015315 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0 0.0 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.1 GO:0086077 gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077)
0.0 0.3 GO:0005351 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.0 0.1 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.0 0.1 GO:0032190 acrosin binding(GO:0032190)
0.0 0.1 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.1 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.0 0.0 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.0 1.1 GO:0008186 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.0 0.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.4 GO:0004622 lysophospholipase activity(GO:0004622)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.2 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 5.4 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.1 3.3 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 3.1 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1 5.6 PID ATM PATHWAY ATM pathway
0.1 3.4 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 2.6 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.7 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 3.7 PID PLK1 PATHWAY PLK1 signaling events
0.0 2.0 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 1.5 PID ATR PATHWAY ATR signaling pathway
0.0 1.0 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 1.3 PID AURORA A PATHWAY Aurora A signaling
0.0 1.2 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.3 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 1.4 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 1.4 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.1 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.3 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.7 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 1.2 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.3 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 1.3 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.3 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.3 ST GA13 PATHWAY G alpha 13 Pathway
0.0 0.2 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.6 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.5 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.2 7.6 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.2 1.5 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.1 1.9 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.1 5.1 REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS Genes involved in Activation of ATR in response to replication stress
0.1 1.2 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.1 4.3 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 4.9 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.1 7.6 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.1 5.0 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 2.0 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.1 3.5 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 2.7 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 1.6 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.8 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 6.6 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.6 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 2.1 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 1.3 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 1.6 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.0 0.7 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.3 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.3 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 4.3 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.0 1.7 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 1.2 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 3.6 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.5 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.3 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.0 0.3 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.7 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.5 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.3 REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION Genes involved in Glucagon signaling in metabolic regulation
0.0 0.5 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.7 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.4 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 0.3 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 3.0 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.1 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 0.3 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.4 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.4 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.1 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.3 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.5 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.4 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.2 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions