ISMARA results: TFEC_MITF_ARNTL

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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for TFEC_MITF_ARNTL_BHLHE41

Z-value: 0.65

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Transcription factors associated with TFEC_MITF_ARNTL_BHLHE41

Gene Symbol	Gene ID	Gene Info
TFEC Ensembl NCBI GeneCards UniProt NextProt	ENSG00000105967.11	transcription factor EC
MITF Ensembl NCBI GeneCards UniProt NextProt	ENSG00000187098.10	melanocyte inducing transcription factor
ARNTL Ensembl NCBI GeneCards UniProt NextProt	ENSG00000133794.13	aryl hydrocarbon receptor nuclear translocator like
BHLHE41 Ensembl NCBI GeneCards UniProt NextProt	ENSG00000123095.5	basic helix-loop-helix family member e41

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
BHLHE41	hg19_v2_chr12_-_26278030_26278060	-0.76	1.1e-04	Click!
TFEC	hg19_v2_chr7_-_115799942_115799955	-0.69	7.2e-04	Click!
ARNTL	hg19_v2_chr11_+_13299186_13299432	-0.56	9.7e-03	Click!
MITF	hg19_v2_chr3_+_69985792_69985874	-0.21	3.6e-01	Click!

Activity profile of TFEC_MITF_ARNTL_BHLHE41 motif

Sorted Z-values of TFEC_MITF_ARNTL_BHLHE41 motif

Top targets:

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr12_-_58146048 Show fit	3.94	ENST00000547281.1 ENST00000546489.1 ENST00000552388.1 ENST00000540325.1 ENST00000312990.6	CDK4 Ensembl NCBI GeneCards UniProt NextProt Show fit	cyclin-dependent kinase 4
chrX_-_100662881 Show fit	3.59	ENST00000218516.3	GLA Ensembl NCBI GeneCards UniProt NextProt Show fit	galactosidase, alpha
chr11_+_67159416 Show fit	3.57	ENST00000307980.2 ENST00000544620.1	RAD9A Ensembl NCBI GeneCards UniProt NextProt Show fit	RAD9 homolog A (S. pombe)
chr12_-_58146128 Show fit	3.44	ENST00000551800.1 ENST00000549606.1 ENST00000257904.6	CDK4 Ensembl NCBI GeneCards UniProt NextProt Show fit	cyclin-dependent kinase 4
chr17_-_7137857 Show fit	3.37	ENST00000005340.5	DVL2 Ensembl NCBI GeneCards UniProt NextProt Show fit	dishevelled segment polarity protein 2
chr10_+_101542462 Show fit	3.20	ENST00000370449.4 ENST00000370434.1	ABCC2 Ensembl NCBI GeneCards UniProt NextProt Show fit	ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chr19_+_49458107 Show fit	3.06	ENST00000539787.1 ENST00000345358.7 ENST00000391871.3 ENST00000415969.2 ENST00000354470.3 ENST00000506183.1 ENST00000293288.8	BAX Ensembl NCBI GeneCards UniProt NextProt Show fit	BCL2-associated X protein
chr22_-_36903101 Show fit	2.78	ENST00000397224.4	FOXRED2 Ensembl NCBI GeneCards UniProt NextProt Show fit	FAD-dependent oxidoreductase domain containing 2
chr12_+_56109810 Show fit	2.51	ENST00000550412.1 ENST00000257899.2 ENST00000548925.1 ENST00000549147.1	RP11-644F5.10 Ensembl NCBI GeneCards UniProt NextProt Show fit BLOC1S1 Ensembl NCBI GeneCards UniProt NextProt Show fit	Uncharacterized protein biogenesis of lysosomal organelles complex-1, subunit 1
chr12_+_56109926 Show fit	2.31	ENST00000547076.1	BLOC1S1 Ensembl NCBI GeneCards UniProt NextProt Show fit	biogenesis of lysosomal organelles complex-1, subunit 1
chr6_-_33385854 Show fit	2.29	ENST00000488478.1	CUTA Ensembl NCBI GeneCards UniProt NextProt Show fit	cutA divalent cation tolerance homolog (E. coli)
chr15_-_72668805 Show fit	2.16	ENST00000268097.5	HEXA Ensembl NCBI GeneCards UniProt NextProt Show fit	hexosaminidase A (alpha polypeptide)
chr15_-_72668185 Show fit	2.09	ENST00000457859.2 ENST00000566304.1 ENST00000567159.1 ENST00000429918.2	HEXA Ensembl NCBI GeneCards UniProt NextProt Show fit	hexosaminidase A (alpha polypeptide)
chr22_-_36903069 Show fit	2.09	ENST00000216187.6 ENST00000423980.1	FOXRED2 Ensembl NCBI GeneCards UniProt NextProt Show fit	FAD-dependent oxidoreductase domain containing 2
chr16_-_28503080 Show fit	2.07	ENST00000565316.1 ENST00000565778.1 ENST00000357857.9 ENST00000568558.1 ENST00000357806.7	CLN3 Ensembl NCBI GeneCards UniProt NextProt Show fit	ceroid-lipofuscinosis, neuronal 3
chr17_-_7137582 Show fit	2.04	ENST00000575756.1 ENST00000575458.1	DVL2 Ensembl NCBI GeneCards UniProt NextProt Show fit	dishevelled segment polarity protein 2
chr16_-_28503357 Show fit	2.02	ENST00000333496.9 ENST00000561505.1 ENST00000567963.1 ENST00000354630.5 ENST00000355477.5 ENST00000357076.5 ENST00000565688.1 ENST00000359984.7	CLN3 Ensembl NCBI GeneCards UniProt NextProt Show fit	ceroid-lipofuscinosis, neuronal 3
chr1_-_21995794 Show fit	2.01	ENST00000542643.2 ENST00000374765.4 ENST00000317967.7	RAP1GAP Ensembl NCBI GeneCards UniProt NextProt Show fit	RAP1 GTPase activating protein
chr3_-_20227619 Show fit	1.97	ENST00000425061.1 ENST00000443724.1 ENST00000421451.1 ENST00000452020.1 ENST00000417364.1 ENST00000306698.2 ENST00000419233.2 ENST00000263753.4 ENST00000383774.1 ENST00000437051.1 ENST00000412868.1 ENST00000429446.3 ENST00000442720.1	SGOL1 Ensembl NCBI GeneCards UniProt NextProt Show fit	shugoshin-like 1 (S. pombe)
chr16_-_28503327 Show fit	1.95	ENST00000535392.1 ENST00000395653.4	CLN3 Ensembl NCBI GeneCards UniProt NextProt Show fit	ceroid-lipofuscinosis, neuronal 3
chr14_-_21852119 Show fit	1.94	ENST00000555943.1	SUPT16H Ensembl NCBI GeneCards UniProt NextProt Show fit	suppressor of Ty 16 homolog (S. cerevisiae)
chr19_+_14544099 Show fit	1.90	ENST00000242783.6 ENST00000586557.1 ENST00000590097.1	PKN1 Ensembl NCBI GeneCards UniProt NextProt Show fit	protein kinase N1
chr1_-_154193091 Show fit	1.76	ENST00000362076.4 ENST00000350592.3 ENST00000368516.1	C1orf43 Ensembl NCBI GeneCards UniProt NextProt Show fit	chromosome 1 open reading frame 43
chr8_+_103876528 Show fit	1.76	ENST00000522939.1 ENST00000524007.1	KB-1507C5.2 Ensembl NCBI GeneCards UniProt NextProt Show fit	HCG15011, isoform CRA_a; Protein LOC100996457
chr11_-_45307817 Show fit	1.76	ENST00000020926.3	SYT13 Ensembl NCBI GeneCards UniProt NextProt Show fit	synaptotagmin XIII
chr20_-_2821271 Show fit	1.72	ENST00000448755.1 ENST00000360652.2	PCED1A Ensembl NCBI GeneCards UniProt NextProt Show fit	PC-esterase domain containing 1A
chr11_+_62538775 Show fit	1.71	ENST00000294168.3 ENST00000526261.1	TAF6L Ensembl NCBI GeneCards UniProt NextProt Show fit	TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
chr5_-_176730733 Show fit	1.63	ENST00000504395.1	RAB24 Ensembl NCBI GeneCards UniProt NextProt Show fit	RAB24, member RAS oncogene family
chr1_-_204329013 Show fit	1.62	ENST00000272203.3 ENST00000414478.1	PLEKHA6 Ensembl NCBI GeneCards UniProt NextProt Show fit	pleckstrin homology domain containing, family A member 6
chr19_-_41256207 Show fit	1.58	ENST00000598485.2 ENST00000470681.1 ENST00000339153.3 ENST00000598729.1	C19orf54 Ensembl NCBI GeneCards UniProt NextProt Show fit	chromosome 19 open reading frame 54
chr16_-_1525016 Show fit	1.57	ENST00000262318.8 ENST00000448525.1	CLCN7 Ensembl NCBI GeneCards UniProt NextProt Show fit	chloride channel, voltage-sensitive 7
chr17_-_46688334 Show fit	1.56	ENST00000239165.7	HOXB7 Ensembl NCBI GeneCards UniProt NextProt Show fit	homeobox B7
chr19_+_40854559 Show fit	1.54	ENST00000598962.1 ENST00000409419.1 ENST00000409587.1 ENST00000602131.1 ENST00000409735.4 ENST00000600948.1 ENST00000356508.5 ENST00000596682.1 ENST00000594908.1	PLD3 Ensembl NCBI GeneCards UniProt NextProt Show fit	phospholipase D family, member 3
chr15_+_75628232 Show fit	1.54	ENST00000267935.8 ENST00000567195.1	COMMD4 Ensembl NCBI GeneCards UniProt NextProt Show fit	COMM domain containing 4
chr15_+_75628394 Show fit	1.52	ENST00000564815.1 ENST00000338995.6	COMMD4 Ensembl NCBI GeneCards UniProt NextProt Show fit	COMM domain containing 4
chr17_+_1627834 Show fit	1.50	ENST00000419248.1 ENST00000418841.1	WDR81 Ensembl NCBI GeneCards UniProt NextProt Show fit	WD repeat domain 81
chr7_+_150759634 Show fit	1.49	ENST00000392826.2 ENST00000461735.1	SLC4A2 Ensembl NCBI GeneCards UniProt NextProt Show fit	solute carrier family 4 (anion exchanger), member 2
chr1_+_199996702 Show fit	1.48	ENST00000367362.3	NR5A2 Ensembl NCBI GeneCards UniProt NextProt Show fit	nuclear receptor subfamily 5, group A, member 2
chr12_+_56110247 Show fit	1.48	ENST00000551926.1	BLOC1S1 Ensembl NCBI GeneCards UniProt NextProt Show fit	biogenesis of lysosomal organelles complex-1, subunit 1
chr14_-_20929624 Show fit	1.46	ENST00000398020.4 ENST00000250489.4	TMEM55B Ensembl NCBI GeneCards UniProt NextProt Show fit	transmembrane protein 55B
chr15_+_75628419 Show fit	1.46	ENST00000567377.1 ENST00000562789.1 ENST00000568301.1	COMMD4 Ensembl NCBI GeneCards UniProt NextProt Show fit	COMM domain containing 4
chr16_+_2570340 Show fit	1.44	ENST00000568263.1 ENST00000293971.6 ENST00000302956.4 ENST00000413459.3 ENST00000566706.1 ENST00000569879.1	AMDHD2 Ensembl NCBI GeneCards UniProt NextProt Show fit	amidohydrolase domain containing 2
chr19_+_45504688 Show fit	1.43	ENST00000221452.8 ENST00000540120.1 ENST00000505236.1	RELB Ensembl NCBI GeneCards UniProt NextProt Show fit	v-rel avian reticuloendotheliosis viral oncogene homolog B
chr8_+_126103921 Show fit	1.42	ENST00000523741.1	NSMCE2 Ensembl NCBI GeneCards UniProt NextProt Show fit	non-SMC element 2, MMS21 homolog (S. cerevisiae)
chr19_+_10812108 Show fit	1.42	ENST00000250237.5 ENST00000592254.1	QTRT1 Ensembl NCBI GeneCards UniProt NextProt Show fit	queuine tRNA-ribosyltransferase 1
chr16_+_28986085 Show fit	1.41	ENST00000565975.1 ENST00000311008.11 ENST00000323081.8 ENST00000334536.8	SPNS1 Ensembl NCBI GeneCards UniProt NextProt Show fit	spinster homolog 1 (Drosophila)
chr16_+_28986134 Show fit	1.35	ENST00000352260.7	SPNS1 Ensembl NCBI GeneCards UniProt NextProt Show fit	spinster homolog 1 (Drosophila)
chr20_-_2821756 Show fit	1.34	ENST00000356872.3 ENST00000439542.1	PCED1A Ensembl NCBI GeneCards UniProt NextProt Show fit	PC-esterase domain containing 1A
chr11_-_61560053 Show fit	1.34	ENST00000537328.1	TMEM258 Ensembl NCBI GeneCards UniProt NextProt Show fit	transmembrane protein 258
chr17_+_62223320 Show fit	1.33	ENST00000580828.1 ENST00000582965.1	SNORA76 Ensembl NCBI GeneCards UniProt NextProt Show fit	small nucleolar RNA, H/ACA box 76
chr6_-_33385655 Show fit	1.33	ENST00000440279.3 ENST00000607266.1	CUTA Ensembl NCBI GeneCards UniProt NextProt Show fit	cutA divalent cation tolerance homolog (E. coli)
chr1_-_154193009 Show fit	1.32	ENST00000368518.1 ENST00000368519.1 ENST00000368521.5	C1orf43 Ensembl NCBI GeneCards UniProt NextProt Show fit	chromosome 1 open reading frame 43
chr5_+_133706865 Show fit	1.31	ENST00000265339.2	UBE2B Ensembl NCBI GeneCards UniProt NextProt Show fit	ubiquitin-conjugating enzyme E2B
chr17_+_48450575 Show fit	1.31	ENST00000338165.4 ENST00000393271.2 ENST00000511519.2	EME1 Ensembl NCBI GeneCards UniProt NextProt Show fit	essential meiotic structure-specific endonuclease 1
chr11_+_61560348 Show fit	1.30	ENST00000535723.1 ENST00000574708.1	FEN1 Ensembl NCBI GeneCards UniProt NextProt Show fit FADS2 Ensembl NCBI GeneCards UniProt NextProt Show fit	flap structure-specific endonuclease 1 fatty acid desaturase 2
chr2_+_27309605 Show fit	1.28	ENST00000260599.6 ENST00000260598.5 ENST00000429697.1	KHK Ensembl NCBI GeneCards UniProt NextProt Show fit	ketohexokinase (fructokinase)
chr1_-_212873267 Show fit	1.26	ENST00000243440.1	BATF3 Ensembl NCBI GeneCards UniProt NextProt Show fit	basic leucine zipper transcription factor, ATF-like 3
chr10_+_69644404 Show fit	1.24	ENST00000212015.6	SIRT1 Ensembl NCBI GeneCards UniProt NextProt Show fit	sirtuin 1
chr22_-_42343117 Show fit	1.24	ENST00000407253.3 ENST00000215980.5	CENPM Ensembl NCBI GeneCards UniProt NextProt Show fit	centromere protein M
chr12_+_56110315 Show fit	1.24	ENST00000548556.1	BLOC1S1 Ensembl NCBI GeneCards UniProt NextProt Show fit	biogenesis of lysosomal organelles complex-1, subunit 1
chr6_-_33385823 Show fit	1.24	ENST00000494751.1 ENST00000374496.3	CUTA Ensembl NCBI GeneCards UniProt NextProt Show fit	cutA divalent cation tolerance homolog (E. coli)
chr12_-_63328817 Show fit	1.22	ENST00000228705.6	PPM1H Ensembl NCBI GeneCards UniProt NextProt Show fit	protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr16_-_5083917 Show fit	1.22	ENST00000312251.3 ENST00000381955.3	NAGPA Ensembl NCBI GeneCards UniProt NextProt Show fit	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
chr22_-_42342692 Show fit	1.22	ENST00000404067.1 ENST00000402338.1	CENPM Ensembl NCBI GeneCards UniProt NextProt Show fit	centromere protein M
chr12_+_54332535 Show fit	1.21	ENST00000243056.3	HOXC13 Ensembl NCBI GeneCards UniProt NextProt Show fit	homeobox C13
chr2_+_85981008 Show fit	1.20	ENST00000306279.3	ATOH8 Ensembl NCBI GeneCards UniProt NextProt Show fit	atonal homolog 8 (Drosophila)
chr19_-_10764509 Show fit	1.20	ENST00000591501.1	ILF3-AS1 Ensembl NCBI GeneCards UniProt NextProt Show fit	ILF3 antisense RNA 1 (head to head)
chr17_+_78075498 Show fit	1.20	ENST00000302262.3	GAA Ensembl NCBI GeneCards UniProt NextProt Show fit	glucosidase, alpha; acid
chr6_+_151646800 Show fit	1.19	ENST00000354675.6	AKAP12 Ensembl NCBI GeneCards UniProt NextProt Show fit	A kinase (PRKA) anchor protein 12
chr16_-_5083589 Show fit	1.16	ENST00000563578.1 ENST00000562346.2	NAGPA Ensembl NCBI GeneCards UniProt NextProt Show fit	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
chr1_-_23520755 Show fit	1.16	ENST00000314113.3	HTR1D Ensembl NCBI GeneCards UniProt NextProt Show fit	5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled
chr16_+_5121814 Show fit	1.14	ENST00000262374.5 ENST00000586840.1	ALG1 Ensembl NCBI GeneCards UniProt NextProt Show fit	ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase
chr7_+_99746514 Show fit	1.11	ENST00000341942.5 ENST00000441173.1	LAMTOR4 Ensembl NCBI GeneCards UniProt NextProt Show fit	late endosomal/lysosomal adaptor, MAPK and MTOR activator 4
chr19_+_40854363 Show fit	1.08	ENST00000599685.1 ENST00000392032.2	PLD3 Ensembl NCBI GeneCards UniProt NextProt Show fit	phospholipase D family, member 3
chr2_+_46926048 Show fit	1.08	ENST00000306503.5	SOCS5 Ensembl NCBI GeneCards UniProt NextProt Show fit	suppressor of cytokine signaling 5
chr1_-_155211017 Show fit	1.07	ENST00000536770.1 ENST00000368373.3	GBA Ensembl NCBI GeneCards UniProt NextProt Show fit	glucosidase, beta, acid
chr6_-_33385870 Show fit	1.07	ENST00000488034.1	CUTA Ensembl NCBI GeneCards UniProt NextProt Show fit	cutA divalent cation tolerance homolog (E. coli)
chr19_-_40854281 Show fit	1.06	ENST00000392035.2	C19orf47 Ensembl NCBI GeneCards UniProt NextProt Show fit	chromosome 19 open reading frame 47
chr1_+_199996733 Show fit	1.06	ENST00000236914.3	NR5A2 Ensembl NCBI GeneCards UniProt NextProt Show fit	nuclear receptor subfamily 5, group A, member 2
chr6_-_33385902 Show fit	1.06	ENST00000374500.5	CUTA Ensembl NCBI GeneCards UniProt NextProt Show fit	cutA divalent cation tolerance homolog (E. coli)
chr17_+_78075361 Show fit	1.03	ENST00000577106.1 ENST00000390015.3	GAA Ensembl NCBI GeneCards UniProt NextProt Show fit	glucosidase, alpha; acid
chrY_+_2709527 Show fit	1.02	ENST00000250784.8	RPS4Y1 Ensembl NCBI GeneCards UniProt NextProt Show fit	ribosomal protein S4, Y-linked 1
chr12_-_2986107 Show fit	1.00	ENST00000359843.3 ENST00000342628.2 ENST00000361953.3	FOXM1 Ensembl NCBI GeneCards UniProt NextProt Show fit	forkhead box M1
chr10_+_99258625 Show fit	1.00	ENST00000370664.3	UBTD1 Ensembl NCBI GeneCards UniProt NextProt Show fit	ubiquitin domain containing 1
chr1_+_221051699 Show fit	0.99	ENST00000366903.6	HLX Ensembl NCBI GeneCards UniProt NextProt Show fit	H2.0-like homeobox
chr9_-_139137648 Show fit	0.97	ENST00000358701.5	QSOX2 Ensembl NCBI GeneCards UniProt NextProt Show fit	quiescin Q6 sulfhydryl oxidase 2
chr2_-_47572207 Show fit	0.96	ENST00000441997.1	AC073283.4 Ensembl NCBI GeneCards UniProt NextProt Show fit	AC073283.4
chr7_-_27196267 Show fit	0.95	ENST00000242159.3	HOXA7 Ensembl NCBI GeneCards UniProt NextProt Show fit	homeobox A7
chr12_-_90103077 Show fit	0.94	ENST00000551310.1	ATP2B1 Ensembl NCBI GeneCards UniProt NextProt Show fit	ATPase, Ca++ transporting, plasma membrane 1
chr17_-_46671323 Show fit	0.93	ENST00000239151.5	HOXB5 Ensembl NCBI GeneCards UniProt NextProt Show fit	homeobox B5
chrY_+_15016013 Show fit	0.93	ENST00000360160.4 ENST00000454054.1	DDX3Y Ensembl NCBI GeneCards UniProt NextProt Show fit	DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
chr2_-_133427767 Show fit	0.93	ENST00000397463.2	LYPD1 Ensembl NCBI GeneCards UniProt NextProt Show fit	LY6/PLAUR domain containing 1
chr22_+_31002779 Show fit	0.93	ENST00000215838.3	TCN2 Ensembl NCBI GeneCards UniProt NextProt Show fit	transcobalamin II
chr2_+_176981307 Show fit	0.92	ENST00000249501.4	HOXD10 Ensembl NCBI GeneCards UniProt NextProt Show fit	homeobox D10
chr1_+_44440575 Show fit	0.92	ENST00000532642.1 ENST00000236067.4 ENST00000471859.2	ATP6V0B Ensembl NCBI GeneCards UniProt NextProt Show fit	ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
chr12_-_114211444 Show fit	0.91	ENST00000510694.2 ENST00000550223.1	RP11-438N16.1 Ensembl NCBI GeneCards UniProt NextProt Show fit	RP11-438N16.1
chrY_+_2709906 Show fit	0.91	ENST00000430575.1	RPS4Y1 Ensembl NCBI GeneCards UniProt NextProt Show fit	ribosomal protein S4, Y-linked 1
chr19_-_36545128 Show fit	0.91	ENST00000538849.1	THAP8 Ensembl NCBI GeneCards UniProt NextProt Show fit	THAP domain containing 8
chr12_+_123849462 Show fit	0.91	ENST00000543072.1	hsa-mir-8072 Ensembl NCBI GeneCards UniProt NextProt Show fit	hsa-mir-8072
chr16_-_2097787 Show fit	0.91	ENST00000566380.1 ENST00000219066.1	NTHL1 Ensembl NCBI GeneCards UniProt NextProt Show fit	nth endonuclease III-like 1 (E. coli)
chr9_-_75695323 Show fit	0.90	ENST00000419959.1	ALDH1A1 Ensembl NCBI GeneCards UniProt NextProt Show fit	aldehyde dehydrogenase 1 family, member A1
chr16_+_5083950 Show fit	0.90	ENST00000588623.1	ALG1 Ensembl NCBI GeneCards UniProt NextProt Show fit	ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase
chr17_+_79935418 Show fit	0.89	ENST00000306729.7 ENST00000306739.4	ASPSCR1 Ensembl NCBI GeneCards UniProt NextProt Show fit	alveolar soft part sarcoma chromosome region, candidate 1
chr20_-_62130474 Show fit	0.88	ENST00000217182.3	EEF1A2 Ensembl NCBI GeneCards UniProt NextProt Show fit	eukaryotic translation elongation factor 1 alpha 2
chr5_-_176730676 Show fit	0.88	ENST00000393611.2 ENST00000303251.6 ENST00000303270.6	RAB24 Ensembl NCBI GeneCards UniProt NextProt Show fit	RAB24, member RAS oncogene family
chr12_+_54378923 Show fit	0.87	ENST00000303460.4	HOXC10 Ensembl NCBI GeneCards UniProt NextProt Show fit	homeobox C10
chr7_+_99070527 Show fit	0.87	ENST00000379724.3	ZNF789 Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger protein 789
chr20_+_2821366 Show fit	0.87	ENST00000453689.1 ENST00000417508.1	VPS16 Ensembl NCBI GeneCards UniProt NextProt Show fit	vacuolar protein sorting 16 homolog (S. cerevisiae)
chr15_+_69591235 Show fit	0.87	ENST00000395407.2 ENST00000558684.1	PAQR5 Ensembl NCBI GeneCards UniProt NextProt Show fit	progestin and adipoQ receptor family member V
chr17_+_78075324 Show fit	0.86	ENST00000570803.1	GAA Ensembl NCBI GeneCards UniProt NextProt Show fit	glucosidase, alpha; acid
chr3_-_20227720 Show fit	0.86	ENST00000412997.1	SGOL1 Ensembl NCBI GeneCards UniProt NextProt Show fit	shugoshin-like 1 (S. pombe)
chr17_-_42200996 Show fit	0.85	ENST00000587135.1 ENST00000225983.6 ENST00000393622.2 ENST00000588703.1	HDAC5 Ensembl NCBI GeneCards UniProt NextProt Show fit	histone deacetylase 5
chr19_+_47634039 Show fit	0.85	ENST00000597808.1 ENST00000413379.3 ENST00000600706.1 ENST00000540850.1 ENST00000598840.1 ENST00000600753.1 ENST00000270225.7 ENST00000392776.3	SAE1 Ensembl NCBI GeneCards UniProt NextProt Show fit	SUMO1 activating enzyme subunit 1
chr22_+_31003133 Show fit	0.85	ENST00000405742.3	TCN2 Ensembl NCBI GeneCards UniProt NextProt Show fit	transcobalamin II
chr17_-_6915646 Show fit	0.84	ENST00000574377.1 ENST00000399541.2 ENST00000399540.2 ENST00000575727.1 ENST00000573939.1	AC027763.2 Ensembl NCBI GeneCards UniProt NextProt Show fit	Uncharacterized protein
chr7_+_100271355 Show fit	0.84	ENST00000436220.1 ENST00000424361.1	GNB2 Ensembl NCBI GeneCards UniProt NextProt Show fit	guanine nucleotide binding protein (G protein), beta polypeptide 2
chr2_+_228189867 Show fit	0.84	ENST00000423098.1 ENST00000304593.9	MFF Ensembl NCBI GeneCards UniProt NextProt Show fit	mitochondrial fission factor
chr3_+_19988736 Show fit	0.84	ENST00000443878.1	RAB5A Ensembl NCBI GeneCards UniProt NextProt Show fit	RAB5A, member RAS oncogene family
chr19_+_8386371 Show fit	0.83	ENST00000600659.2	RPS28 Ensembl NCBI GeneCards UniProt NextProt Show fit	ribosomal protein S28
chr1_-_155211065 Show fit	0.83	ENST00000427500.3	GBA Ensembl NCBI GeneCards UniProt NextProt Show fit	glucosidase, beta, acid
chr2_-_47572105 Show fit	0.82	ENST00000419035.1 ENST00000448713.1 ENST00000450550.1 ENST00000413185.2	AC073283.4 Ensembl NCBI GeneCards UniProt NextProt Show fit	AC073283.4
chr17_+_46970134 Show fit	0.82	ENST00000503641.1 ENST00000514808.1	ATP5G1 Ensembl NCBI GeneCards UniProt NextProt Show fit	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
chr2_+_240323439 Show fit	0.82	ENST00000428471.1 ENST00000413029.1	AC062017.1 Ensembl NCBI GeneCards UniProt NextProt Show fit	Uncharacterized protein
chr19_-_5340730 Show fit	0.81	ENST00000372412.4 ENST00000357368.4 ENST00000262963.6 ENST00000348075.2 ENST00000353284.2	PTPRS Ensembl NCBI GeneCards UniProt NextProt Show fit	protein tyrosine phosphatase, receptor type, S
chr1_-_11865982 Show fit	0.81	ENST00000418034.1	MTHFR Ensembl NCBI GeneCards UniProt NextProt Show fit	methylenetetrahydrofolate reductase (NAD(P)H)
chrX_-_34675391 Show fit	0.81	ENST00000275954.3	TMEM47 Ensembl NCBI GeneCards UniProt NextProt Show fit	transmembrane protein 47
chr4_-_100871506 Show fit	0.80	ENST00000296417.5	H2AFZ Ensembl NCBI GeneCards UniProt NextProt Show fit	H2A histone family, member Z
chr19_+_41305330 Show fit	0.80	ENST00000593972.1	EGLN2 Ensembl NCBI GeneCards UniProt NextProt Show fit	egl-9 family hypoxia-inducible factor 2
chr19_-_40854417 Show fit	0.80	ENST00000582006.1 ENST00000582783.1	C19orf47 Ensembl NCBI GeneCards UniProt NextProt Show fit	chromosome 19 open reading frame 47
chr12_-_90102594 Show fit	0.77	ENST00000428670.3	ATP2B1 Ensembl NCBI GeneCards UniProt NextProt Show fit	ATPase, Ca++ transporting, plasma membrane 1
chr3_-_126076264 Show fit	0.76	ENST00000296233.3	KLF15 Ensembl NCBI GeneCards UniProt NextProt Show fit	Kruppel-like factor 15
chr7_-_47622156 Show fit	0.76	ENST00000457718.1	TNS3 Ensembl NCBI GeneCards UniProt NextProt Show fit	tensin 3
chr22_+_35776828 Show fit	0.75	ENST00000216117.8	HMOX1 Ensembl NCBI GeneCards UniProt NextProt Show fit	heme oxygenase (decycling) 1
chr7_+_150758304 Show fit	0.75	ENST00000482950.1 ENST00000463414.1 ENST00000310317.5	SLC4A2 Ensembl NCBI GeneCards UniProt NextProt Show fit	solute carrier family 4 (anion exchanger), member 2
chr2_+_176972000 Show fit	0.75	ENST00000249504.5	HOXD11 Ensembl NCBI GeneCards UniProt NextProt Show fit	homeobox D11
chr17_+_79935464 Show fit	0.74	ENST00000581647.1 ENST00000580534.1 ENST00000579684.1	ASPSCR1 Ensembl NCBI GeneCards UniProt NextProt Show fit	alveolar soft part sarcoma chromosome region, candidate 1
chrX_+_72783026 Show fit	0.74	ENST00000373504.6 ENST00000373502.5	CHIC1 Ensembl NCBI GeneCards UniProt NextProt Show fit	cysteine-rich hydrophobic domain 1
chr12_+_53645870 Show fit	0.74	ENST00000329548.4	MFSD5 Ensembl NCBI GeneCards UniProt NextProt Show fit	major facilitator superfamily domain containing 5
chr5_+_133707252 Show fit	0.73	ENST00000506787.1 ENST00000507277.1	UBE2B Ensembl NCBI GeneCards UniProt NextProt Show fit	ubiquitin-conjugating enzyme E2B
chr20_+_18118703 Show fit	0.73	ENST00000464792.1	CSRP2BP Ensembl NCBI GeneCards UniProt NextProt Show fit	CSRP2 binding protein
chr16_+_83986827 Show fit	0.72	ENST00000393306.1 ENST00000565123.1	OSGIN1 Ensembl NCBI GeneCards UniProt NextProt Show fit	oxidative stress induced growth inhibitor 1
chr2_-_220083692 Show fit	0.72	ENST00000265316.3	ABCB6 Ensembl NCBI GeneCards UniProt NextProt Show fit	ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr2_-_220083671 Show fit	0.72	ENST00000439002.2	ABCB6 Ensembl NCBI GeneCards UniProt NextProt Show fit	ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr10_-_99258135 Show fit	0.72	ENST00000327238.10 ENST00000327277.7 ENST00000355839.6 ENST00000437002.1 ENST00000422685.1	MMS19 Ensembl NCBI GeneCards UniProt NextProt Show fit	MMS19 nucleotide excision repair homolog (S. cerevisiae)
chr7_+_100271446 Show fit	0.72	ENST00000419828.1 ENST00000427895.1	GNB2 Ensembl NCBI GeneCards UniProt NextProt Show fit	guanine nucleotide binding protein (G protein), beta polypeptide 2
chr22_-_39268308 Show fit	0.71	ENST00000407418.3	CBX6 Ensembl NCBI GeneCards UniProt NextProt Show fit	chromobox homolog 6
chr15_+_91260552 Show fit	0.71	ENST00000355112.3 ENST00000560509.1	BLM Ensembl NCBI GeneCards UniProt NextProt Show fit	Bloom syndrome, RecQ helicase-like
chr19_+_32836499 Show fit	0.71	ENST00000311921.4 ENST00000544431.1 ENST00000355898.5	ZNF507 Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger protein 507
chr6_-_109703663 Show fit	0.70	ENST00000368961.5	CD164 Ensembl NCBI GeneCards UniProt NextProt Show fit	CD164 molecule, sialomucin
chr17_-_18266660 Show fit	0.70	ENST00000582653.1 ENST00000352886.6	SHMT1 Ensembl NCBI GeneCards UniProt NextProt Show fit	serine hydroxymethyltransferase 1 (soluble)
chr1_+_11866207 Show fit	0.69	ENST00000312413.6 ENST00000346436.6	CLCN6 Ensembl NCBI GeneCards UniProt NextProt Show fit	chloride channel, voltage-sensitive 6
chr17_-_79791118 Show fit	0.68	ENST00000576431.1 ENST00000575061.1 ENST00000455127.2 ENST00000572645.1 ENST00000538396.1 ENST00000573478.1	FAM195B Ensembl NCBI GeneCards UniProt NextProt Show fit	family with sequence similarity 195, member B
chr17_-_18218270 Show fit	0.68	ENST00000321105.5	TOP3A Ensembl NCBI GeneCards UniProt NextProt Show fit	topoisomerase (DNA) III alpha
chr16_-_70323422 Show fit	0.68	ENST00000261772.8	AARS Ensembl NCBI GeneCards UniProt NextProt Show fit	alanyl-tRNA synthetase
chr8_-_95274536 Show fit	0.68	ENST00000297596.2 ENST00000396194.2	GEM Ensembl NCBI GeneCards UniProt NextProt Show fit	GTP binding protein overexpressed in skeletal muscle
chr12_+_85673868 Show fit	0.68	ENST00000316824.3	ALX1 Ensembl NCBI GeneCards UniProt NextProt Show fit	ALX homeobox 1
chr16_+_770975 Show fit	0.67	ENST00000569529.1 ENST00000564000.1 ENST00000219535.3	FAM173A Ensembl NCBI GeneCards UniProt NextProt Show fit	family with sequence similarity 173, member A
chrX_+_153627231 Show fit	0.66	ENST00000406022.2	RPL10 Ensembl NCBI GeneCards UniProt NextProt Show fit	ribosomal protein L10
chrX_+_102631248 Show fit	0.66	ENST00000361298.4 ENST00000372645.3 ENST00000372635.1	NGFRAP1 Ensembl NCBI GeneCards UniProt NextProt Show fit	nerve growth factor receptor (TNFRSF16) associated protein 1
chr12_+_51632638 Show fit	0.66	ENST00000549732.2	DAZAP2 Ensembl NCBI GeneCards UniProt NextProt Show fit	DAZ associated protein 2
chr16_+_2570431 Show fit	0.66	ENST00000563556.1	AMDHD2 Ensembl NCBI GeneCards UniProt NextProt Show fit	amidohydrolase domain containing 2
chr4_-_164253738 Show fit	0.66	ENST00000509586.1 ENST00000504391.1 ENST00000512819.1	NPY1R Ensembl NCBI GeneCards UniProt NextProt Show fit	neuropeptide Y receptor Y1
chr11_-_71814422 Show fit	0.65	ENST00000278671.5	LAMTOR1 Ensembl NCBI GeneCards UniProt NextProt Show fit	late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
chr5_-_172198190 Show fit	0.64	ENST00000239223.3	DUSP1 Ensembl NCBI GeneCards UniProt NextProt Show fit	dual specificity phosphatase 1
chr15_-_83316254 Show fit	0.64	ENST00000567678.1 ENST00000450751.2	CPEB1 Ensembl NCBI GeneCards UniProt NextProt Show fit	cytoplasmic polyadenylation element binding protein 1
chr7_+_4815238 Show fit	0.64	ENST00000348624.4 ENST00000401897.1	AP5Z1 Ensembl NCBI GeneCards UniProt NextProt Show fit	adaptor-related protein complex 5, zeta 1 subunit
chr17_-_42200958 Show fit	0.64	ENST00000336057.5	HDAC5 Ensembl NCBI GeneCards UniProt NextProt Show fit	histone deacetylase 5
chr7_-_99699538 Show fit	0.63	ENST00000343023.6 ENST00000303887.5	MCM7 Ensembl NCBI GeneCards UniProt NextProt Show fit	minichromosome maintenance complex component 7
chr10_-_32217717 Show fit	0.63	ENST00000396144.4 ENST00000375245.4 ENST00000344936.2 ENST00000375250.5	ARHGAP12 Ensembl NCBI GeneCards UniProt NextProt Show fit	Rho GTPase activating protein 12
chr12_+_54378849 Show fit	0.63	ENST00000515593.1	HOXC10 Ensembl NCBI GeneCards UniProt NextProt Show fit	homeobox C10
chrY_+_15016725 Show fit	0.63	ENST00000336079.3	DDX3Y Ensembl NCBI GeneCards UniProt NextProt Show fit	DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
chr5_+_41904431 Show fit	0.63	ENST00000381647.2	C5orf51 Ensembl NCBI GeneCards UniProt NextProt Show fit	chromosome 5 open reading frame 51
chr11_+_67776012 Show fit	0.62	ENST00000539229.1	ALDH3B1 Ensembl NCBI GeneCards UniProt NextProt Show fit	aldehyde dehydrogenase 3 family, member B1
chr2_-_120980939 Show fit	0.62	ENST00000426077.2	TMEM185B Ensembl NCBI GeneCards UniProt NextProt Show fit	transmembrane protein 185B
chr12_+_90102729 Show fit	0.62	ENST00000605386.1	LINC00936 Ensembl NCBI GeneCards UniProt NextProt Show fit	long intergenic non-protein coding RNA 936
chrX_+_102883887 Show fit	0.62	ENST00000372625.3 ENST00000372624.3	TCEAL1 Ensembl NCBI GeneCards UniProt NextProt Show fit	transcription elongation factor A (SII)-like 1
chrX_-_15872914 Show fit	0.62	ENST00000380291.1 ENST00000545766.1 ENST00000421527.2 ENST00000329235.2	AP1S2 Ensembl NCBI GeneCards UniProt NextProt Show fit	adaptor-related protein complex 1, sigma 2 subunit
chr6_+_36562132 Show fit	0.60	ENST00000373715.6 ENST00000339436.7	SRSF3 Ensembl NCBI GeneCards UniProt NextProt Show fit	serine/arginine-rich splicing factor 3
chr19_-_15236470 Show fit	0.60	ENST00000533747.1 ENST00000598709.1 ENST00000534378.1	ILVBL Ensembl NCBI GeneCards UniProt NextProt Show fit	ilvB (bacterial acetolactate synthase)-like
chr19_-_49016847 Show fit	0.60	ENST00000598924.1	CTC-273B12.10 Ensembl NCBI GeneCards UniProt NextProt Show fit	CTC-273B12.10
chr17_-_40346477 Show fit	0.60	ENST00000593209.1 ENST00000587427.1 ENST00000588352.1 ENST00000414034.3 ENST00000590249.1	GHDC Ensembl NCBI GeneCards UniProt NextProt Show fit	GH3 domain containing
chr6_+_151561085 Show fit	0.60	ENST00000402676.2	AKAP12 Ensembl NCBI GeneCards UniProt NextProt Show fit	A kinase (PRKA) anchor protein 12
chr1_-_68962782 Show fit	0.60	ENST00000456315.2	DEPDC1 Ensembl NCBI GeneCards UniProt NextProt Show fit	DEP domain containing 1
chr1_-_154909329 Show fit	0.60	ENST00000368467.3	PMVK Ensembl NCBI GeneCards UniProt NextProt Show fit	phosphomevalonate kinase
chr1_+_17248418 Show fit	0.60	ENST00000375541.5	CROCC Ensembl NCBI GeneCards UniProt NextProt Show fit	ciliary rootlet coiled-coil, rootletin
chr17_-_18218237 Show fit	0.59	ENST00000542570.1	TOP3A Ensembl NCBI GeneCards UniProt NextProt Show fit	topoisomerase (DNA) III alpha
chr4_-_47465666 Show fit	0.58	ENST00000381571.4	COMMD8 Ensembl NCBI GeneCards UniProt NextProt Show fit	COMM domain containing 8
chr19_+_41305406 Show fit	0.58	ENST00000406058.2 ENST00000593726.1	EGLN2 Ensembl NCBI GeneCards UniProt NextProt Show fit	egl-9 family hypoxia-inducible factor 2
chr2_-_40006357 Show fit	0.58	ENST00000505747.1	THUMPD2 Ensembl NCBI GeneCards UniProt NextProt Show fit	THUMP domain containing 2
chr20_+_2821340 Show fit	0.58	ENST00000380445.3 ENST00000380469.3	VPS16 Ensembl NCBI GeneCards UniProt NextProt Show fit	vacuolar protein sorting 16 homolog (S. cerevisiae)
chr22_-_39268192 Show fit	0.57	ENST00000216083.6	CBX6 Ensembl NCBI GeneCards UniProt NextProt Show fit	chromobox homolog 6
chr17_-_26684473 Show fit	0.57	ENST00000540200.1	POLDIP2 Ensembl NCBI GeneCards UniProt NextProt Show fit	polymerase (DNA-directed), delta interacting protein 2
chr8_-_126104055 Show fit	0.57	ENST00000318410.7	KIAA0196 Ensembl NCBI GeneCards UniProt NextProt Show fit	KIAA0196
chr14_-_54955721 Show fit	0.56	ENST00000554908.1	GMFB Ensembl NCBI GeneCards UniProt NextProt Show fit	glia maturation factor, beta
chr11_-_61560254 Show fit	0.56	ENST00000543510.1	TMEM258 Ensembl NCBI GeneCards UniProt NextProt Show fit	transmembrane protein 258
chr1_-_68962805 Show fit	0.56	ENST00000370966.5	DEPDC1 Ensembl NCBI GeneCards UniProt NextProt Show fit	DEP domain containing 1
chr16_-_2168079 Show fit	0.56	ENST00000488185.2	PKD1 Ensembl NCBI GeneCards UniProt NextProt Show fit	polycystic kidney disease 1 (autosomal dominant)
chr17_+_40688190 Show fit	0.56	ENST00000225927.2	NAGLU Ensembl NCBI GeneCards UniProt NextProt Show fit	N-acetylglucosaminidase, alpha
chr14_-_20922960 Show fit	0.56	ENST00000553640.1 ENST00000488532.2	OSGEP Ensembl NCBI GeneCards UniProt NextProt Show fit	O-sialoglycoprotein endopeptidase
chr22_-_51017084 Show fit	0.55	ENST00000360719.2 ENST00000457250.1 ENST00000440709.1	CPT1B Ensembl NCBI GeneCards UniProt NextProt Show fit	carnitine palmitoyltransferase 1B (muscle)

Network of associatons between targets according to the STRING database.

First level regulatory network of TFEC_MITF_ARNTL_BHLHE41

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.5	6.0	GO:0035752	lysosomal lumen pH elevation(GO:0035752)
1.4	5.4	GO:0014022	neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
1.1	3.2	GO:0050787	antibiotic metabolic process(GO:0016999) detoxification of mercury ion(GO:0050787)
1.0	3.1	GO:0043181	vacuolar sequestering(GO:0043181)
1.0	3.1	GO:0048597	B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597) positive regulation of apoptotic DNA fragmentation(GO:1902512)
0.7	2.0	GO:0010845	positive regulation of reciprocal meiotic recombination(GO:0010845)
0.7	2.0	GO:1903697	negative regulation of microvillus assembly(GO:1903697)
0.6	5.1	GO:1904637	response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
0.5	3.6	GO:1902231	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.5	5.6	GO:0046477	glycosylceramide catabolic process(GO:0046477)
0.5	7.6	GO:0060155	platelet dense granule organization(GO:0060155)
0.4	1.2	GO:1990619	histone H3-K9 deacetylation(GO:1990619)
0.4	1.2	GO:0070407	oxidation-dependent protein catabolic process(GO:0070407)
0.4	1.5	GO:1904482	response to tetrahydrofolate(GO:1904481) cellular response to tetrahydrofolate(GO:1904482)
0.4	0.8	GO:0032764	negative regulation of mast cell cytokine production(GO:0032764)
0.4	2.2	GO:0006001	fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.4	2.5	GO:0061113	pancreas morphogenesis(GO:0061113)
0.3	1.3	GO:0072429	response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.3	1.3	GO:0043137	DNA replication, removal of RNA primer(GO:0043137)
0.3	1.9	GO:0035407	histone H3-T11 phosphorylation(GO:0035407)
0.3	1.4	GO:0034184	positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.3	2.5	GO:0045629	negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.3	0.8	GO:0031662	regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662) response to DDT(GO:0046680) histone H3-S10 phosphorylation involved in chromosome condensation(GO:2000775)
0.3	0.8	GO:0034164	negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.3	1.1	GO:0002949	tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.3	2.1	GO:0019262	N-acetylneuraminate catabolic process(GO:0019262)
0.3	1.0	GO:0042144	vacuole fusion, non-autophagic(GO:0042144)
0.2	1.0	GO:0090299	regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.2	0.7	GO:0002940	tRNA N2-guanine methylation(GO:0002940)
0.2	1.5	GO:1900063	regulation of peroxisome organization(GO:1900063)
0.2	0.2	GO:2000506	negative regulation of energy homeostasis(GO:2000506)
0.2	0.7	GO:1902568	regulation of eosinophil degranulation(GO:0043309) positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.2	5.0	GO:0042340	keratan sulfate catabolic process(GO:0042340)
0.2	0.7	GO:0006419	alanyl-tRNA aminoacylation(GO:0006419)
0.2	0.7	GO:1901842	negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.2	2.8	GO:0015889	cobalamin transport(GO:0015889)
0.2	0.6	GO:0006258	UDP-glucose catabolic process(GO:0006258)
0.2	0.6	GO:0019287	isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.2	1.2	GO:0060620	regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.2	2.7	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
0.2	1.7	GO:1990034	cellular response to corticosterone stimulus(GO:0071386) calcium ion export from cell(GO:1990034)
0.2	0.6	GO:0002416	IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
0.2	0.5	GO:0061580	colon epithelial cell migration(GO:0061580)
0.2	0.7	GO:0072287	metanephric distal tubule morphogenesis(GO:0072287)
0.2	2.4	GO:0021520	spinal cord motor neuron cell fate specification(GO:0021520)
0.1	0.6	GO:0032053	ciliary basal body organization(GO:0032053) positive regulation of protein localization to cilium(GO:1903566)
0.1	0.4	GO:0010259	multicellular organism aging(GO:0010259)
0.1	0.4	GO:1901207	regulation of heart looping(GO:1901207)
0.1	0.4	GO:0000961	negative regulation of mitochondrial RNA catabolic process(GO:0000961)
0.1	0.1	GO:0016256	N-glycan processing to lysosome(GO:0016256)
0.1	1.7	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
0.1	0.5	GO:0060535	trachea cartilage morphogenesis(GO:0060535)
0.1	2.6	GO:0003376	sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.1	1.7	GO:0033299	secretion of lysosomal enzymes(GO:0033299)
0.1	0.7	GO:0044806	G-quadruplex DNA unwinding(GO:0044806)
0.1	1.5	GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.1	1.1	GO:0014827	intestine smooth muscle contraction(GO:0014827)
0.1	0.3	GO:1902463	protein localization to cell leading edge(GO:1902463)
0.1	0.4	GO:0070318	positive regulation of G0 to G1 transition(GO:0070318)
0.1	0.4	GO:0044314	protein K27-linked ubiquitination(GO:0044314)
0.1	0.4	GO:0005985	sucrose metabolic process(GO:0005985)
0.1	0.5	GO:0033274	response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.1	0.8	GO:0090238	positive regulation of arachidonic acid secretion(GO:0090238)
0.1	0.3	GO:1903564	regulation of protein localization to cilium(GO:1903564) negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.1	0.3	GO:1903251	multi-ciliated epithelial cell differentiation(GO:1903251)
0.1	0.5	GO:0000738	DNA catabolic process, exonucleolytic(GO:0000738)
0.1	1.8	GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.1	0.4	GO:0060168	positive regulation of adenosine receptor signaling pathway(GO:0060168) regulation of G-protein coupled receptor internalization(GO:1904020)
0.1	0.7	GO:1905098	negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.1	0.8	GO:0021546	rhombomere development(GO:0021546)
0.1	1.0	GO:0045617	negative regulation of keratinocyte differentiation(GO:0045617)
0.1	0.3	GO:0015993	L-ascorbic acid transport(GO:0015882) molecular hydrogen transport(GO:0015993) transepithelial L-ascorbic acid transport(GO:0070904)
0.1	0.8	GO:1901029	negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.1	0.3	GO:1901301	regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.1	0.3	GO:0045925	positive regulation of female receptivity(GO:0045925)
0.1	0.8	GO:0000160	phosphorelay signal transduction system(GO:0000160)
0.1	1.8	GO:0015886	heme transport(GO:0015886)
0.1	0.4	GO:0019303	D-ribose catabolic process(GO:0019303)
0.1	0.3	GO:0019516	lactate oxidation(GO:0019516)
0.1	0.7	GO:0010587	miRNA catabolic process(GO:0010587)
0.1	0.2	GO:1902990	mitotic telomere maintenance via semi-conservative replication(GO:1902990)
0.1	0.7	GO:0019471	4-hydroxyproline metabolic process(GO:0019471)
0.1	1.4	GO:0032688	negative regulation of interferon-beta production(GO:0032688)
0.1	0.1	GO:0072003	kidney rudiment formation(GO:0072003)
0.1	0.3	GO:0046452	dihydrofolate metabolic process(GO:0046452)
0.1	0.4	GO:2000676	positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.1	1.1	GO:0043985	histone H4-R3 methylation(GO:0043985)
0.1	0.4	GO:0098502	DNA dephosphorylation(GO:0098502)
0.1	0.8	GO:0086024	adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1	1.2	GO:0035878	nail development(GO:0035878)
0.1	0.3	GO:0042264	peptidyl-aspartic acid hydroxylation(GO:0042264)
0.1	0.4	GO:0097089	methyl-branched fatty acid metabolic process(GO:0097089)
0.1	0.4	GO:0034316	negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.1	0.4	GO:0019464	glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.1	0.6	GO:0060754	positive regulation of mast cell chemotaxis(GO:0060754)
0.1	1.0	GO:2000781	positive regulation of double-strand break repair(GO:2000781)
0.1	0.2	GO:0071963	establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.1	3.0	GO:0034080	CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.1	0.2	GO:1903031	regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.1	0.2	GO:0070309	lens fiber cell morphogenesis(GO:0070309)
0.1	2.8	GO:0097502	mannosylation(GO:0097502)
0.1	0.6	GO:0036444	calcium ion transmembrane import into mitochondrion(GO:0036444)
0.1	1.4	GO:0002115	store-operated calcium entry(GO:0002115)
0.1	0.2	GO:0019348	dolichol metabolic process(GO:0019348)
0.1	0.2	GO:1902269	positive regulation of polyamine transmembrane transport(GO:1902269)
0.1	1.6	GO:0006744	ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.1	0.5	GO:0051533	positive regulation of NFAT protein import into nucleus(GO:0051533)
0.1	0.1	GO:0071400	cellular response to oleic acid(GO:0071400)
0.1	0.3	GO:0019242	methylglyoxal biosynthetic process(GO:0019242)
0.1	0.6	GO:0046185	aldehyde catabolic process(GO:0046185)
0.1	0.2	GO:0016340	calcium-dependent cell-matrix adhesion(GO:0016340)
0.1	1.3	GO:0006265	DNA topological change(GO:0006265)
0.1	1.5	GO:0090051	negative regulation of cell migration involved in sprouting angiogenesis(GO:0090051)
0.1	1.6	GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.1	0.3	GO:0014050	negative regulation of glutamate secretion(GO:0014050)
0.1	0.8	GO:0048262	determination of dorsal/ventral asymmetry(GO:0048262)
0.1	0.8	GO:0018206	peptidyl-methionine modification(GO:0018206)
0.1	0.2	GO:0006147	guanine catabolic process(GO:0006147)
0.1	0.3	GO:0014057	positive regulation of acetylcholine secretion, neurotransmission(GO:0014057)
0.1	1.1	GO:1904714	regulation of chaperone-mediated autophagy(GO:1904714)
0.1	0.2	GO:0006114	glycerol biosynthetic process(GO:0006114)
0.1	0.2	GO:0044205	'de novo' UMP biosynthetic process(GO:0044205)
0.1	0.5	GO:0021769	orbitofrontal cortex development(GO:0021769)
0.1	0.5	GO:0006975	DNA damage induced protein phosphorylation(GO:0006975)
0.0	0.1	GO:1990828	response to putrescine(GO:1904585) cellular response to putrescine(GO:1904586) hepatocyte dedifferentiation(GO:1990828)
0.0	0.4	GO:0006335	DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0	0.6	GO:0015691	cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.0	0.4	GO:0006880	intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0	0.1	GO:0035281	pre-miRNA export from nucleus(GO:0035281)
0.0	0.1	GO:0035606	peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.0	0.1	GO:1900126	negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.0	0.3	GO:0045900	negative regulation of translational elongation(GO:0045900)
0.0	0.1	GO:0090149	mitochondrial membrane fission(GO:0090149)
0.0	0.1	GO:0007343	egg activation(GO:0007343)
0.0	0.1	GO:0032877	positive regulation of DNA endoreduplication(GO:0032877)
0.0	0.6	GO:0060272	embryonic skeletal joint morphogenesis(GO:0060272)
0.0	1.2	GO:0045603	positive regulation of endothelial cell differentiation(GO:0045603)
0.0	0.1	GO:0051182	coenzyme transport(GO:0051182)
0.0	1.0	GO:0000028	ribosomal small subunit assembly(GO:0000028)
0.0	0.1	GO:0000921	septin ring assembly(GO:0000921) septin ring organization(GO:0031106)
0.0	0.3	GO:0044565	dendritic cell proliferation(GO:0044565)
0.0	0.3	GO:0051344	regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.0	0.1	GO:0002879	leukocyte chemotaxis involved in inflammatory response(GO:0002232) positive regulation of acute inflammatory response to non-antigenic stimulus(GO:0002879)
0.0	1.5	GO:0043011	myeloid dendritic cell differentiation(GO:0043011)
0.0	0.1	GO:1901857	positive regulation of cellular respiration(GO:1901857)
0.0	0.2	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.0	0.2	GO:0051902	negative regulation of mitochondrial depolarization(GO:0051902)
0.0	0.3	GO:0030200	heparan sulfate proteoglycan catabolic process(GO:0030200)
0.0	0.2	GO:0044111	development involved in symbiotic interaction(GO:0044111)
0.0	1.1	GO:0051770	positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770)
0.0	3.3	GO:0015701	bicarbonate transport(GO:0015701)
0.0	0.2	GO:0021993	initiation of neural tube closure(GO:0021993)
0.0	0.3	GO:2000124	regulation of endocannabinoid signaling pathway(GO:2000124)
0.0	2.7	GO:0071377	cellular response to glucagon stimulus(GO:0071377)
0.0	0.9	GO:0071850	mitotic cell cycle arrest(GO:0071850)
0.0	0.4	GO:0071569	protein ufmylation(GO:0071569)
0.0	0.1	GO:0061687	detoxification of inorganic compound(GO:0061687)
0.0	0.3	GO:2000035	regulation of stem cell division(GO:2000035)
0.0	0.1	GO:0006089	lactate metabolic process(GO:0006089)
0.0	0.1	GO:0000117	regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.0	0.7	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)
0.0	0.4	GO:1902074	response to salt(GO:1902074)
0.0	0.3	GO:0007256	activation of JNKK activity(GO:0007256)
0.0	0.2	GO:0046203	spermidine catabolic process(GO:0046203)
0.0	0.1	GO:0043376	regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.0	1.0	GO:1905144	acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.0	0.1	GO:0048250	mitochondrial iron ion transport(GO:0048250)
0.0	0.1	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.0	0.1	GO:0003335	corneocyte development(GO:0003335)
0.0	0.1	GO:0045588	positive regulation of gamma-delta T cell differentiation(GO:0045588) positive regulation of gamma-delta T cell activation(GO:0046645)
0.0	0.3	GO:0035694	mitochondrial protein catabolic process(GO:0035694)
0.0	0.1	GO:0072237	proximal convoluted tubule development(GO:0072019) metanephric proximal convoluted tubule development(GO:0072229) metanephric proximal tubule development(GO:0072237)
0.0	0.1	GO:0071163	DNA replication preinitiation complex assembly(GO:0071163)
0.0	0.0	GO:0001658	branching involved in ureteric bud morphogenesis(GO:0001658)
0.0	0.1	GO:1903028	positive regulation of opsonization(GO:1903028)
0.0	2.1	GO:1903959	regulation of anion transmembrane transport(GO:1903959)
0.0	0.3	GO:1901142	insulin metabolic process(GO:1901142)
0.0	0.3	GO:2001206	positive regulation of osteoclast development(GO:2001206)
0.0	0.2	GO:0045716	positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
0.0	0.1	GO:0000454	snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.0	0.3	GO:0002759	regulation of antimicrobial humoral response(GO:0002759)
0.0	0.2	GO:0006045	N-acetylglucosamine biosynthetic process(GO:0006045) glucosamine-containing compound biosynthetic process(GO:1901073)
0.0	0.8	GO:0072112	renal filtration cell differentiation(GO:0061318) glomerular visceral epithelial cell differentiation(GO:0072112)
0.0	0.0	GO:0070827	mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960) chromatin maintenance(GO:0070827)
0.0	0.3	GO:0050957	equilibrioception(GO:0050957)
0.0	0.7	GO:0001502	cartilage condensation(GO:0001502)
0.0	0.5	GO:0042474	middle ear morphogenesis(GO:0042474)
0.0	0.1	GO:0060164	regulation of timing of neuron differentiation(GO:0060164)
0.0	0.6	GO:0097034	mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0	0.5	GO:0038166	angiotensin-activated signaling pathway(GO:0038166)
0.0	0.1	GO:2000174	regulation of pro-T cell differentiation(GO:2000174) positive regulation of pro-T cell differentiation(GO:2000176)
0.0	0.3	GO:1900377	negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.0	0.5	GO:0009162	deoxyribonucleoside monophosphate metabolic process(GO:0009162)
0.0	0.1	GO:0014029	neural crest formation(GO:0014029)
0.0	0.8	GO:0006895	Golgi to endosome transport(GO:0006895)
0.0	0.1	GO:0044210	'de novo' CTP biosynthetic process(GO:0044210)
0.0	2.3	GO:0006400	tRNA modification(GO:0006400)
0.0	0.2	GO:0097033	respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0	0.5	GO:0071420	cellular response to histamine(GO:0071420)
0.0	1.2	GO:0097421	liver regeneration(GO:0097421)
0.0	0.1	GO:0035526	retrograde transport, plasma membrane to Golgi(GO:0035526)
0.0	3.1	GO:0030433	ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0	0.1	GO:0006500	N-terminal protein palmitoylation(GO:0006500)
0.0	0.5	GO:0021554	optic nerve development(GO:0021554)
0.0	0.1	GO:0097029	mature conventional dendritic cell differentiation(GO:0097029)
0.0	1.0	GO:0046856	phosphatidylinositol dephosphorylation(GO:0046856)
0.0	0.2	GO:0097461	ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.0	0.1	GO:0097151	positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0	0.1	GO:2000286	receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.0	1.2	GO:0006270	DNA replication initiation(GO:0006270)
0.0	0.3	GO:0001522	pseudouridine synthesis(GO:0001522)
0.0	0.1	GO:0051581	negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0	0.2	GO:0070327	thyroid hormone transport(GO:0070327)
0.0	0.2	GO:0008535	respiratory chain complex IV assembly(GO:0008535)
0.0	0.6	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0	0.3	GO:0051152	positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0	0.5	GO:0006853	carnitine shuttle(GO:0006853)
0.0	0.1	GO:0090521	glomerular visceral epithelial cell migration(GO:0090521)
0.0	0.6	GO:0070584	mitochondrion morphogenesis(GO:0070584)
0.0	0.2	GO:0002028	regulation of sodium ion transport(GO:0002028)
0.0	0.1	GO:0006121	mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.0	0.1	GO:0032380	regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0	0.1	GO:1902630	regulation of membrane hyperpolarization(GO:1902630)
0.0	0.2	GO:0071557	histone H3-K27 demethylation(GO:0071557)
0.0	0.0	GO:0000472	endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
0.0	0.2	GO:0009048	dosage compensation by inactivation of X chromosome(GO:0009048)
0.0	0.2	GO:0006538	glutamate catabolic process(GO:0006538)
0.0	0.1	GO:0035698	CD8-positive, alpha-beta T cell extravasation(GO:0035697) CD8-positive, alpha-beta cytotoxic T cell extravasation(GO:0035698) T cell extravasation(GO:0072683) regulation of T cell extravasation(GO:2000407) regulation of CD8-positive, alpha-beta T cell extravasation(GO:2000449) regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation(GO:2000452)
0.0	0.3	GO:0070914	UV-damage excision repair(GO:0070914)
0.0	1.7	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0	0.1	GO:0006043	glucosamine catabolic process(GO:0006043)
0.0	0.1	GO:0044208	'de novo' AMP biosynthetic process(GO:0044208)
0.0	0.6	GO:0048025	negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0	0.1	GO:0021898	regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) cerebral cortex GABAergic interneuron fate commitment(GO:0021893) commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
0.0	0.1	GO:1903232	melanosome assembly(GO:1903232)
0.0	0.1	GO:0043335	protein unfolding(GO:0043335)
0.0	0.2	GO:0038003	opioid receptor signaling pathway(GO:0038003)
0.0	0.1	GO:0071651	positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.0	0.5	GO:0032211	negative regulation of telomere maintenance via telomerase(GO:0032211)
0.0	0.0	GO:0035359	negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.0	0.6	GO:0090200	positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0	0.1	GO:0051106	positive regulation of DNA ligation(GO:0051106)
0.0	0.3	GO:0098792	xenophagy(GO:0098792)
0.0	0.1	GO:1902775	mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0	0.1	GO:0098876	vesicle-mediated transport to the plasma membrane(GO:0098876)
0.0	0.1	GO:0008588	release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0	0.5	GO:0042776	mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0	0.2	GO:0006884	cell volume homeostasis(GO:0006884)
0.0	0.2	GO:0032264	IMP salvage(GO:0032264)
0.0	0.1	GO:1902044	regulation of Fas signaling pathway(GO:1902044)
0.0	0.1	GO:0098886	modification of dendritic spine(GO:0098886)
0.0	0.1	GO:0001561	fatty acid alpha-oxidation(GO:0001561)
0.0	0.0	GO:0070346	positive regulation of fat cell proliferation(GO:0070346)
0.0	0.5	GO:0000027	ribosomal large subunit assembly(GO:0000027)
0.0	0.2	GO:1903393	positive regulation of focal adhesion assembly(GO:0051894) positive regulation of adherens junction organization(GO:1903393)
0.0	0.3	GO:0018126	protein hydroxylation(GO:0018126)
0.0	0.2	GO:0099601	regulation of neurotransmitter receptor activity(GO:0099601)
0.0	0.1	GO:0015866	ADP transport(GO:0015866)
0.0	0.1	GO:0042908	xenobiotic transport(GO:0042908)
0.0	0.2	GO:0051151	negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0	0.1	GO:0072502	cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0	0.1	GO:0010609	mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609)
0.0	0.1	GO:0006049	UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0	0.2	GO:0030043	actin filament fragmentation(GO:0030043)
0.0	0.2	GO:0015816	glycine transport(GO:0015816)
0.0	0.1	GO:1905146	lysosomal protein catabolic process(GO:1905146)
0.0	0.1	GO:0044789	modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.0	0.3	GO:1903206	negative regulation of hydrogen peroxide-induced cell death(GO:1903206)
0.0	0.3	GO:0048172	regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0	0.0	GO:0061004	pattern specification involved in kidney development(GO:0061004) renal system pattern specification(GO:0072048) pattern specification involved in metanephros development(GO:0072268)
0.0	0.1	GO:0086053	AV node cell to bundle of His cell communication by electrical coupling(GO:0086053)
0.0	0.1	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
0.0	0.2	GO:0045974	miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0	0.9	GO:0010501	RNA secondary structure unwinding(GO:0010501)
0.0	0.1	GO:0015811	L-cystine transport(GO:0015811)
0.0	0.5	GO:0071173	mitotic spindle assembly checkpoint(GO:0007094) spindle assembly checkpoint(GO:0071173)
0.0	0.5	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.0	0.2	GO:0006477	protein sulfation(GO:0006477)
0.0	0.2	GO:1903690	negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0	0.0	GO:0051924	regulation of calcium ion transport(GO:0051924)
0.0	0.1	GO:0050873	brown fat cell differentiation(GO:0050873)
0.0	0.3	GO:0097067	cellular response to thyroid hormone stimulus(GO:0097067)
0.0	0.2	GO:0007379	segment specification(GO:0007379)
0.0	0.1	GO:2000210	positive regulation of anoikis(GO:2000210)
0.0	0.3	GO:0090140	regulation of mitochondrial fission(GO:0090140)
0.0	0.1	GO:0098532	histone H3-K27 trimethylation(GO:0098532)
0.0	0.4	GO:0031648	protein destabilization(GO:0031648)
0.0	0.2	GO:0001675	acrosome assembly(GO:0001675)
0.0	0.0	GO:0043438	acetoacetic acid metabolic process(GO:0043438)
0.0	0.1	GO:0035331	negative regulation of hippo signaling(GO:0035331)
0.0	0.3	GO:0007021	tubulin complex assembly(GO:0007021)
0.0	0.2	GO:0060575	intestinal epithelial cell differentiation(GO:0060575)
0.0	0.1	GO:0070072	proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0	0.1	GO:0051496	positive regulation of stress fiber assembly(GO:0051496)
0.0	0.1	GO:0036066	protein O-linked fucosylation(GO:0036066)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	1.9	GO:0035101	FACT complex(GO:0035101)
0.6	4.8	GO:0097129	cyclin D2-CDK4 complex(GO:0097129)
0.3	3.1	GO:0030896	checkpoint clamp complex(GO:0030896)
0.2	1.3	GO:0048476	Holliday junction resolvase complex(GO:0048476)
0.2	3.1	GO:0097136	Bcl-2 family protein complex(GO:0097136)
0.2	2.6	GO:0046581	intercellular canaliculus(GO:0046581)
0.2	2.0	GO:0033503	HULC complex(GO:0033503)
0.2	1.2	GO:0071817	MMXD complex(GO:0071817)
0.2	2.5	GO:0071986	Ragulator complex(GO:0071986)
0.2	1.2	GO:0033553	rDNA heterochromatin(GO:0033553)
0.2	5.9	GO:0031083	BLOC-1 complex(GO:0031083)
0.2	0.9	GO:0031510	SUMO activating enzyme complex(GO:0031510)
0.2	0.8	GO:0097125	cyclin B1-CDK1 complex(GO:0097125)
0.2	1.4	GO:0030915	Smc5-Smc6 complex(GO:0030915)
0.1	0.7	GO:0002133	polycystin complex(GO:0002133)
0.1	1.1	GO:0000408	EKC/KEOPS complex(GO:0000408)
0.1	2.1	GO:0000808	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1	0.5	GO:0071458	integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.1	0.4	GO:0005960	glycine cleavage complex(GO:0005960)
0.1	1.4	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.1	1.6	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.1	1.4	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.1	0.8	GO:0001740	Barr body(GO:0001740)
0.1	0.3	GO:0033597	mitotic checkpoint complex(GO:0033597) bub1-bub3 complex(GO:1990298)
0.1	0.4	GO:0070288	intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.1	16.4	GO:0043202	lysosomal lumen(GO:0043202)
0.1	1.8	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.1	0.2	GO:0070557	PCNA-p21 complex(GO:0070557)
0.1	0.7	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.1	0.3	GO:0031084	BLOC-2 complex(GO:0031084)
0.1	1.9	GO:0032591	dendritic spine membrane(GO:0032591)
0.1	0.3	GO:1990742	microvesicle(GO:1990742)
0.1	0.4	GO:1990246	uniplex complex(GO:1990246)
0.1	0.9	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1	0.3	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
0.1	5.3	GO:0016235	aggresome(GO:0016235)
0.1	1.0	GO:0030914	STAGA complex(GO:0030914)
0.0	0.2	GO:0031074	nucleocytoplasmic shuttling complex(GO:0031074)
0.0	0.4	GO:0097452	GAIT complex(GO:0097452)
0.0	0.2	GO:0071008	U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0	0.6	GO:0042555	MCM complex(GO:0042555)
0.0	0.1	GO:0000243	commitment complex(GO:0000243)
0.0	0.3	GO:1990726	Lsm1-7-Pat1 complex(GO:1990726)
0.0	6.2	GO:0005901	caveola(GO:0005901)
0.0	0.7	GO:0035749	myelin sheath adaxonal region(GO:0035749)
0.0	0.6	GO:0035253	ciliary rootlet(GO:0035253)
0.0	0.3	GO:0034751	aryl hydrocarbon receptor complex(GO:0034751)
0.0	0.2	GO:0033186	CAF-1 complex(GO:0033186)
0.0	0.2	GO:0034388	Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0	0.3	GO:0000220	vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0	0.4	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0	0.2	GO:1990604	IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0	0.3	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0	0.8	GO:0000800	lateral element(GO:0000800)
0.0	0.1	GO:1902937	inward rectifier potassium channel complex(GO:1902937)
0.0	2.0	GO:0042645	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0	0.5	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0	0.3	GO:0032541	cortical endoplasmic reticulum(GO:0032541)
0.0	0.1	GO:0031082	BLOC complex(GO:0031082)
0.0	0.2	GO:0090571	RNA polymerase II transcription repressor complex(GO:0090571)
0.0	0.3	GO:0000421	autophagosome membrane(GO:0000421)
0.0	0.2	GO:0031012	extracellular matrix(GO:0031012)
0.0	0.1	GO:0045273	mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0	0.8	GO:0071011	precatalytic spliceosome(GO:0071011)
0.0	0.2	GO:0008622	epsilon DNA polymerase complex(GO:0008622)
0.0	1.9	GO:0097610	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0	0.5	GO:0030663	COPI-coated vesicle membrane(GO:0030663)
0.0	0.2	GO:0031010	ISWI-type complex(GO:0031010)
0.0	0.4	GO:0005662	DNA replication factor A complex(GO:0005662)
0.0	0.5	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.0	0.2	GO:0005827	polar microtubule(GO:0005827)
0.0	0.7	GO:0005680	anaphase-promoting complex(GO:0005680)
0.0	0.1	GO:0005826	actomyosin contractile ring(GO:0005826)
0.0	0.2	GO:0005787	signal peptidase complex(GO:0005787)
0.0	0.2	GO:0005828	kinetochore microtubule(GO:0005828)
0.0	0.6	GO:0044291	cell-cell contact zone(GO:0044291)
0.0	0.6	GO:0030140	trans-Golgi network transport vesicle(GO:0030140)
0.0	0.5	GO:1902711	GABA-A receptor complex(GO:1902711)
0.0	0.5	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0	0.3	GO:0030877	beta-catenin destruction complex(GO:0030877)
0.0	0.4	GO:0005685	U1 snRNP(GO:0005685)
0.0	0.1	GO:0035032	phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0	0.1	GO:1990111	spermatoproteasome complex(GO:1990111)
0.0	0.4	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.0	0.1	GO:0044611	nuclear pore inner ring(GO:0044611)
0.0	1.5	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0	1.8	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.0	0.2	GO:0030981	cortical microtubule cytoskeleton(GO:0030981)
0.0	0.1	GO:0098559	cytoplasmic side of early endosome membrane(GO:0098559)
0.0	0.1	GO:0090661	box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.0	0.1	GO:0045323	interleukin-1 receptor complex(GO:0045323)
0.0	1.8	GO:0000784	nuclear chromosome, telomeric region(GO:0000784)
0.0	0.5	GO:0051233	spindle midzone(GO:0051233)
0.0	0.1	GO:0097487	multivesicular body, internal vesicle(GO:0097487)
0.0	0.8	GO:0032592	integral component of mitochondrial membrane(GO:0032592)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.0	3.1	GO:0004574	oligo-1,6-glucosidase activity(GO:0004574)
0.6	3.6	GO:0008853	exodeoxyribonuclease III activity(GO:0008853)
0.5	3.6	GO:0016936	galactoside binding(GO:0016936)
0.5	3.0	GO:0046624	sphingolipid transporter activity(GO:0046624)
0.5	1.4	GO:0015439	heme-transporting ATPase activity(GO:0015439)
0.5	4.3	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.4	1.2	GO:0046969	histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969)
0.4	1.2	GO:0070362	mitochondrial light strand promoter anti-sense binding(GO:0070361) mitochondrial heavy strand promoter anti-sense binding(GO:0070362) mitochondrial heavy strand promoter sense binding(GO:0070364)
0.4	1.9	GO:0004348	glucosylceramidase activity(GO:0004348)
0.4	1.1	GO:0061711	N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.3	1.9	GO:0035402	histone kinase activity (H3-T11 specific)(GO:0035402)
0.3	1.5	GO:0070905	serine binding(GO:0070905)
0.3	1.2	GO:0070180	large ribosomal subunit rRNA binding(GO:0070180)
0.3	0.9	GO:0019948	SUMO activating enzyme activity(GO:0019948)
0.3	1.4	GO:0008479	queuine tRNA-ribosyltransferase activity(GO:0008479)
0.3	3.1	GO:0051434	BH3 domain binding(GO:0051434)
0.3	1.0	GO:0003943	N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.2	1.5	GO:0008309	double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.2	3.4	GO:0004630	phospholipase D activity(GO:0004630)
0.2	0.9	GO:0030550	acetylcholine receptor inhibitor activity(GO:0030550)
0.2	0.7	GO:0004813	alanine-tRNA ligase activity(GO:0004813)
0.2	0.9	GO:0008534	oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534)
0.2	0.6	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
0.2	2.7	GO:0031419	cobalamin binding(GO:0031419)
0.2	1.0	GO:0016971	flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.2	0.8	GO:0001601	peptide YY receptor activity(GO:0001601)
0.2	0.6	GO:0019912	cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.2	0.6	GO:0033867	Fas-activated serine/threonine kinase activity(GO:0033867)
0.2	2.9	GO:0015929	hexosaminidase activity(GO:0015929)
0.2	0.7	GO:0016230	sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.2	3.2	GO:0043225	anion transmembrane-transporting ATPase activity(GO:0043225)
0.2	0.5	GO:0008859	exoribonuclease II activity(GO:0008859)
0.2	1.5	GO:0001025	RNA polymerase III transcription factor binding(GO:0001025)
0.2	1.5	GO:0034597	phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.2	0.9	GO:1990825	sequence-specific mRNA binding(GO:1990825)
0.1	1.8	GO:0019826	oxygen sensor activity(GO:0019826)
0.1	1.3	GO:0003917	DNA topoisomerase type I activity(GO:0003917)
0.1	0.4	GO:0048244	phytanoyl-CoA dioxygenase activity(GO:0048244)
0.1	0.2	GO:0030337	DNA polymerase processivity factor activity(GO:0030337)
0.1	0.7	GO:0072345	NAADP-sensitive calcium-release channel activity(GO:0072345)
0.1	0.8	GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.1	0.7	GO:0004809	tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.1	0.7	GO:0043183	vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1	1.2	GO:0043176	amine binding(GO:0043176) serotonin binding(GO:0051378)
0.1	0.5	GO:0005471	ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
0.1	0.6	GO:0019770	IgG receptor activity(GO:0019770)
0.1	1.5	GO:0030976	thiamine pyrophosphate binding(GO:0030976)
0.1	2.2	GO:0008179	adenylate cyclase binding(GO:0008179)
0.1	1.3	GO:0008821	crossover junction endodeoxyribonuclease activity(GO:0008821)
0.1	5.4	GO:0005109	frizzled binding(GO:0005109)
0.1	2.7	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.1	0.4	GO:0042132	fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.1	0.5	GO:0004489	methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.1	0.3	GO:0004844	uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.1	0.4	GO:0004967	glucagon receptor activity(GO:0004967)
0.1	0.9	GO:0018479	benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.1	0.3	GO:0004597	peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.1	0.4	GO:0031685	adenosine receptor binding(GO:0031685)
0.1	0.3	GO:0070890	L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.1	0.3	GO:0016250	N-sulfoglucosamine sulfohydrolase activity(GO:0016250) hydrolase activity, acting on acid sulfur-nitrogen bonds(GO:0016826)
0.1	0.9	GO:1990446	U1 snRNP binding(GO:1990446)
0.1	0.4	GO:0004047	aminomethyltransferase activity(GO:0004047)
0.1	0.4	GO:0072590	N-acetyl-L-aspartate-L-glutamate ligase activity(GO:0072590)
0.1	0.7	GO:0000403	Y-form DNA binding(GO:0000403) four-way junction helicase activity(GO:0009378)
0.1	0.5	GO:0004945	angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.1	3.9	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1	0.3	GO:0016898	D-lactate dehydrogenase (cytochrome) activity(GO:0004458) oxidoreductase activity, acting on the CH-OH group of donors, cytochrome as acceptor(GO:0016898)
0.1	0.5	GO:0042500	aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1	0.6	GO:0008269	JAK pathway signal transduction adaptor activity(GO:0008269)
0.1	2.4	GO:0005247	voltage-gated chloride channel activity(GO:0005247)
0.1	0.8	GO:0048039	ubiquinone binding(GO:0048039)
0.1	2.8	GO:0000030	mannosyltransferase activity(GO:0000030)
0.1	0.3	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
0.1	0.3	GO:0003976	UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.1	0.7	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.1	1.7	GO:0003688	DNA replication origin binding(GO:0003688)
0.1	0.6	GO:0004095	carnitine O-palmitoyltransferase activity(GO:0004095)
0.1	0.7	GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.1	0.2	GO:0004980	melanocyte-stimulating hormone receptor activity(GO:0004980)
0.1	1.2	GO:0015279	store-operated calcium channel activity(GO:0015279)
0.1	0.9	GO:0016423	tRNA (guanine) methyltransferase activity(GO:0016423)
0.1	6.8	GO:0005507	copper ion binding(GO:0005507)
0.1	0.2	GO:0015633	zinc transporting ATPase activity(GO:0015633)
0.1	0.3	GO:0032422	purine-rich negative regulatory element binding(GO:0032422)
0.1	0.3	GO:0004167	dopachrome isomerase activity(GO:0004167)
0.1	0.2	GO:0034511	U3 snoRNA binding(GO:0034511)
0.1	0.4	GO:0016833	oxo-acid-lyase activity(GO:0016833)
0.1	0.2	GO:0034038	deoxyhypusine synthase activity(GO:0034038)
0.1	0.8	GO:0043008	ATP-dependent protein binding(GO:0043008)
0.1	0.3	GO:0004347	glucose-6-phosphate isomerase activity(GO:0004347)
0.1	0.5	GO:0070087	chromo shadow domain binding(GO:0070087)
0.1	0.8	GO:0035374	chondroitin sulfate binding(GO:0035374)
0.1	0.2	GO:0008892	guanine deaminase activity(GO:0008892)
0.0	0.0	GO:0038181	bile acid receptor activity(GO:0038181)
0.0	0.2	GO:0051734	ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0	0.1	GO:0010698	acetyltransferase activator activity(GO:0010698)
0.0	1.0	GO:0031698	beta-2 adrenergic receptor binding(GO:0031698)
0.0	0.2	GO:0016639	oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.0	0.3	GO:0008195	phosphatidate phosphatase activity(GO:0008195)
0.0	0.4	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.0	0.1	GO:0090631	pre-miRNA transporter activity(GO:0090631)
0.0	0.3	GO:0004127	cytidylate kinase activity(GO:0004127)
0.0	0.5	GO:0022851	GABA-gated chloride ion channel activity(GO:0022851)
0.0	0.7	GO:0070569	uridylyltransferase activity(GO:0070569)
0.0	1.2	GO:0035925	mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0	0.1	GO:0055131	C3HC4-type RING finger domain binding(GO:0055131)
0.0	1.4	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.0	0.1	GO:0008969	phosphohistidine phosphatase activity(GO:0008969)
0.0	4.7	GO:0050660	flavin adenine dinucleotide binding(GO:0050660)
0.0	0.7	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
0.0	0.3	GO:0035368	selenocysteine insertion sequence binding(GO:0035368)
0.0	0.1	GO:0036033	mediator complex binding(GO:0036033)
0.0	0.1	GO:0031626	beta-endorphin binding(GO:0031626)
0.0	1.0	GO:0042609	CD4 receptor binding(GO:0042609)
0.0	0.2	GO:0042978	ornithine decarboxylase activator activity(GO:0042978)
0.0	0.2	GO:0098519	nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0	0.1	GO:0004365	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0	0.3	GO:0008273	calcium, potassium:sodium antiporter activity(GO:0008273)
0.0	0.3	GO:0019238	cyclohydrolase activity(GO:0019238)
0.0	0.1	GO:0031728	CCR3 chemokine receptor binding(GO:0031728)
0.0	0.3	GO:0008379	thioredoxin peroxidase activity(GO:0008379)
0.0	0.3	GO:0060002	plus-end directed microfilament motor activity(GO:0060002)
0.0	0.2	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.0	0.1	GO:0003883	CTP synthase activity(GO:0003883)
0.0	1.7	GO:0005246	calcium channel regulator activity(GO:0005246)
0.0	0.8	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.0	0.1	GO:1990189	peptide-serine-N-acetyltransferase activity(GO:1990189)
0.0	0.3	GO:0070324	thyroid hormone binding(GO:0070324)
0.0	0.2	GO:0008823	cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0	0.2	GO:0071535	RING-like zinc finger domain binding(GO:0071535)
0.0	0.1	GO:1990050	phosphatidic acid transporter activity(GO:1990050)
0.0	0.9	GO:0008171	O-methyltransferase activity(GO:0008171)
0.0	1.1	GO:0031491	nucleosome binding(GO:0031491)
0.0	2.7	GO:0004879	RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0	0.7	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0	0.3	GO:0097371	MDM2/MDM4 family protein binding(GO:0097371)
0.0	0.1	GO:0050252	retinol O-fatty-acyltransferase activity(GO:0050252)
0.0	0.2	GO:0071933	Arp2/3 complex binding(GO:0071933)
0.0	1.8	GO:0019843	rRNA binding(GO:0019843)
0.0	0.2	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0	0.1	GO:0016842	amidine-lyase activity(GO:0016842)
0.0	0.3	GO:0015232	heme transporter activity(GO:0015232)
0.0	0.2	GO:0050119	N-acetylglucosamine deacetylase activity(GO:0050119)
0.0	0.1	GO:0008559	xenobiotic-transporting ATPase activity(GO:0008559)
0.0	4.0	GO:0051082	unfolded protein binding(GO:0051082)
0.0	0.2	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0	0.1	GO:0001602	pancreatic polypeptide receptor activity(GO:0001602)
0.0	0.2	GO:0004985	opioid receptor activity(GO:0004985)
0.0	1.2	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
0.0	0.1	GO:0052839	inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.0	0.6	GO:0005527	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0	0.2	GO:0071558	histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0	0.1	GO:0004342	glucosamine-6-phosphate deaminase activity(GO:0004342)
0.0	0.4	GO:0008603	cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0	0.1	GO:0005119	smoothened binding(GO:0005119)
0.0	0.3	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.0	0.2	GO:0099602	acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0	1.1	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0	0.2	GO:0003876	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0	0.4	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.0	0.1	GO:0004605	phosphatidate cytidylyltransferase activity(GO:0004605)
0.0	0.4	GO:0051537	2 iron, 2 sulfur cluster binding(GO:0051537)
0.0	0.8	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
0.0	0.2	GO:0015187	glycine transmembrane transporter activity(GO:0015187)
0.0	0.1	GO:0001069	regulatory region RNA binding(GO:0001069)
0.0	0.0	GO:0010309	acireductone dioxygenase [iron(II)-requiring] activity(GO:0010309)
0.0	0.6	GO:0003707	steroid hormone receptor activity(GO:0003707)
0.0	0.3	GO:0005542	folic acid binding(GO:0005542)
0.0	0.1	GO:0004459	L-lactate dehydrogenase activity(GO:0004459)
0.0	0.3	GO:0009982	pseudouridine synthase activity(GO:0009982)
0.0	0.6	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.0	0.2	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.0	0.8	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624)
0.0	0.5	GO:0003746	translation elongation factor activity(GO:0003746)
0.0	0.2	GO:0019534	toxin transporter activity(GO:0019534)
0.0	1.6	GO:0005544	calcium-dependent phospholipid binding(GO:0005544)
0.0	0.2	GO:0015379	potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0	0.1	GO:0032051	clathrin light chain binding(GO:0032051)
0.0	0.1	GO:0047961	glycine N-acyltransferase activity(GO:0047961)
0.0	0.1	GO:0003985	acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.0	0.1	GO:0003827	alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0	0.1	GO:0015315	hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0	0.0	GO:0051185	coenzyme transporter activity(GO:0051185)
0.0	0.1	GO:0086077	gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077)
0.0	0.3	GO:0005351	sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.0	0.1	GO:0015184	L-cystine transmembrane transporter activity(GO:0015184)
0.0	0.1	GO:0032190	acrosin binding(GO:0032190)
0.0	0.1	GO:0034513	box H/ACA snoRNA binding(GO:0034513)
0.0	0.1	GO:0031752	D5 dopamine receptor binding(GO:0031752)
0.0	0.0	GO:0031731	CCR6 chemokine receptor binding(GO:0031731)
0.0	1.1	GO:0008186	ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.0	0.1	GO:0016907	G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0	0.4	GO:0004622	lysophospholipase activity(GO:0004622)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	4.2	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1	5.4	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.1	3.3	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.1	3.1	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1	5.6	PID ATM PATHWAY	ATM pathway
0.1	3.4	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.0	2.6	ST GA12 PATHWAY	G alpha 12 Pathway
0.0	0.7	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.0	3.7	PID PLK1 PATHWAY	PLK1 signaling events
0.0	2.0	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.0	1.5	PID ATR PATHWAY	ATR signaling pathway
0.0	1.0	PID FOXM1 PATHWAY	FOXM1 transcription factor network
0.0	1.3	PID AURORA A PATHWAY	Aurora A signaling
0.0	1.2	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.0	0.3	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.0	1.4	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.0	1.4	PID IL12 2PATHWAY	IL12-mediated signaling events
0.0	0.1	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.0	0.3	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.0	0.7	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.0	1.2	PID IL4 2PATHWAY	IL4-mediated signaling events
0.0	0.3	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.0	1.3	PID CMYB PATHWAY	C-MYB transcription factor network
0.0	0.3	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.0	0.3	ST GA13 PATHWAY	G alpha 13 Pathway
0.0	0.2	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0	0.6	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	4.5	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.2	7.6	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.2	1.5	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.1	1.9	REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION	Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.1	5.1	REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS	Genes involved in Activation of ATR in response to replication stress
0.1	1.2	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.1	4.3	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.1	4.9	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.1	7.6	REACTOME MEIOTIC RECOMBINATION	Genes involved in Meiotic Recombination
0.1	5.0	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.1	2.0	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.1	3.5	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
0.0	2.7	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.0	1.6	REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA	Genes involved in G beta:gamma signalling through PLC beta
0.0	0.8	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.0	6.6	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.0	0.6	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.0	2.1	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	1.3	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	1.6	REACTOME ELONGATION ARREST AND RECOVERY	Genes involved in Elongation arrest and recovery
0.0	0.7	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	0.3	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.3	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.0	4.3	REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS	Genes involved in Glycerophospholipid biosynthesis
0.0	1.7	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.0	1.2	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	3.6	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.0	0.5	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.0	0.3	REACTOME REGULATORY RNA PATHWAYS	Genes involved in Regulatory RNA pathways
0.0	0.3	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.0	0.7	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.0	0.5	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	0.3	REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION	Genes involved in Glucagon signaling in metabolic regulation
0.0	0.5	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.0	0.7	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.0	0.4	REACTOME GLUCAGON TYPE LIGAND RECEPTORS	Genes involved in Glucagon-type ligand receptors
0.0	0.3	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
0.0	3.0	REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0	0.1	REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX	Genes involved in Association of licensing factors with the pre-replicative complex
0.0	0.3	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	0.4	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors
0.0	0.4	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.1	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0	0.3	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0	0.5	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	0.4	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.0	0.2	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions

Results for TFEC_MITF_ARNTL_BHLHE41

Z-value: 0.65

Motif logo

Transcription factors associated with TFEC_MITF_ARNTL_BHLHE41

Activity-expression correlation:

Activity profile of TFEC_MITF_ARNTL_BHLHE41 motif

Sorted Z-values of TFEC_MITF_ARNTL_BHLHE41 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of TFEC_MITF_ARNTL_BHLHE41

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in C2:CP:REACTOME category: