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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for TGIF1

Z-value: 0.42

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Transcription factors associated with TGIF1

Gene Symbol Gene ID Gene Info
TGIF1
ENSG00000177426.16 TGFB induced factor homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TGIF1hg19_v2_chr18_+_3447572_34476070.417.3e-02Click!

Activity profile of TGIF1 motif

Sorted Z-values of TGIF1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr9_-_33447584 1.24 ENST00000297991.4
AQP3
aquaporin 3 (Gill blood group)
chr12_+_86268065 1.09 ENST00000551529.1
ENST00000256010.6
NTS
neurotensin
chr15_+_65337708 0.75 ENST00000334287.2
SLC51B
solute carrier family 51, beta subunit
chr2_+_228678550 0.72 ENST00000409189.3
ENST00000358813.4
CCL20
chemokine (C-C motif) ligand 20
chr17_+_68165657 0.54 ENST00000243457.3
KCNJ2
potassium inwardly-rectifying channel, subfamily J, member 2
chr8_-_20161466 0.45 ENST00000381569.1
LZTS1
leucine zipper, putative tumor suppressor 1
chr17_-_66287257 0.42 ENST00000327268.4
SLC16A6
solute carrier family 16, member 6
chr20_-_5591626 0.42 ENST00000379019.4
GPCPD1
glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)
chr20_-_31124186 0.40 ENST00000375678.3
C20orf112
chromosome 20 open reading frame 112
chr4_+_88896819 0.40 ENST00000237623.7
ENST00000395080.3
ENST00000508233.1
ENST00000360804.4
SPP1
secreted phosphoprotein 1
chrX_-_153775426 0.38 ENST00000393562.2
G6PD
glucose-6-phosphate dehydrogenase
chr7_+_95115210 0.38 ENST00000428113.1
ENST00000325885.5
ASB4
ankyrin repeat and SOCS box containing 4
chr16_+_31044413 0.37 ENST00000394998.1
STX4
syntaxin 4
chr16_-_2205352 0.34 ENST00000563192.1
RP11-304L19.5
RP11-304L19.5
chr16_+_2198604 0.34 ENST00000210187.6
RAB26
RAB26, member RAS oncogene family
chr3_-_52719888 0.33 ENST00000458294.1
PBRM1
polybromo 1
chr2_-_152589670 0.32 ENST00000604864.1
ENST00000603639.1
NEB
nebulin
chr3_+_52719936 0.31 ENST00000418458.1
ENST00000394799.2
GNL3
guanine nucleotide binding protein-like 3 (nucleolar)
chr3_-_123168551 0.31 ENST00000462833.1
ADCY5
adenylate cyclase 5
chr16_+_31366536 0.31 ENST00000562522.1
ITGAX
integrin, alpha X (complement component 3 receptor 4 subunit)
chr1_-_238108575 0.30 ENST00000604646.1
MTRNR2L11
MT-RNR2-like 11 (pseudogene)
chr11_+_842928 0.30 ENST00000397408.1
TSPAN4
tetraspanin 4
chr11_+_842808 0.30 ENST00000397397.2
ENST00000397411.2
ENST00000397396.1
TSPAN4
tetraspanin 4
chr19_+_51153045 0.29 ENST00000458538.1
C19orf81
chromosome 19 open reading frame 81
chr17_-_39341594 0.29 ENST00000398472.1
KRTAP4-1
keratin associated protein 4-1
chr9_+_34652164 0.29 ENST00000441545.2
ENST00000553620.1
IL11RA
interleukin 11 receptor, alpha
chr9_+_130911723 0.28 ENST00000277480.2
ENST00000373013.2
ENST00000540948.1
LCN2
lipocalin 2
chr1_-_91317072 0.28 ENST00000435649.2
ENST00000443802.1
RP4-665J23.1
RP4-665J23.1
chr10_-_10504285 0.27 ENST00000602311.1
RP11-271F18.4
RP11-271F18.4
chr14_+_70346125 0.27 ENST00000361956.3
ENST00000381280.4
SMOC1
SPARC related modular calcium binding 1
chrX_+_49019061 0.27 ENST00000376339.1
ENST00000425661.2
ENST00000458388.1
ENST00000412696.2
MAGIX
MAGI family member, X-linked
chr9_+_130911770 0.26 ENST00000372998.1
LCN2
lipocalin 2
chr17_-_46623441 0.26 ENST00000330070.4
HOXB2
homeobox B2
chr16_+_31044812 0.26 ENST00000313843.3
STX4
syntaxin 4
chr1_+_186649754 0.25 ENST00000608917.1
RP5-973M2.2
RP5-973M2.2
chr22_-_30960876 0.25 ENST00000401975.1
ENST00000428682.1
ENST00000423299.1
GAL3ST1
galactose-3-O-sulfotransferase 1
chr6_+_127439749 0.25 ENST00000356698.4
RSPO3
R-spondin 3
chr16_-_67217844 0.24 ENST00000563902.1
ENST00000561621.1
ENST00000290881.7
KIAA0895L
KIAA0895-like
chr1_-_186649543 0.24 ENST00000367468.5
PTGS2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
chr1_-_146696901 0.24 ENST00000369272.3
ENST00000441068.2
FMO5
flavin containing monooxygenase 5
chr16_+_31366455 0.24 ENST00000268296.4
ITGAX
integrin, alpha X (complement component 3 receptor 4 subunit)
chr12_+_25348139 0.24 ENST00000557540.2
ENST00000381356.4
LYRM5
LYR motif containing 5
chr14_+_21785693 0.24 ENST00000382933.4
ENST00000557351.1
RPGRIP1
retinitis pigmentosa GTPase regulator interacting protein 1
chr14_+_100842735 0.24 ENST00000554998.1
ENST00000402312.3
ENST00000335290.6
ENST00000554175.1
WDR25
WD repeat domain 25
chr14_+_103566481 0.24 ENST00000380069.3
EXOC3L4
exocyst complex component 3-like 4
chr6_+_31105426 0.24 ENST00000547221.1
PSORS1C1
psoriasis susceptibility 1 candidate 1
chr4_-_2420357 0.23 ENST00000511071.1
ENST00000509171.1
ENST00000290974.2
ZFYVE28
zinc finger, FYVE domain containing 28
chr7_-_50628745 0.23 ENST00000380984.4
ENST00000357936.5
ENST00000426377.1
DDC
dopa decarboxylase (aromatic L-amino acid decarboxylase)
chr19_-_47164386 0.23 ENST00000391916.2
ENST00000410105.2
DACT3
dishevelled-binding antagonist of beta-catenin 3
chr16_+_69458428 0.23 ENST00000512062.1
ENST00000307892.8
CYB5B
cytochrome b5 type B (outer mitochondrial membrane)
chr11_-_2924720 0.23 ENST00000455942.2
SLC22A18AS
solute carrier family 22 (organic cation transporter), member 18 antisense
chr2_+_220436917 0.23 ENST00000243786.2
INHA
inhibin, alpha
chr18_+_3449821 0.22 ENST00000407501.2
ENST00000405385.3
ENST00000546979.1
TGIF1
TGFB-induced factor homeobox 1
chrM_+_5824 0.22 ENST00000361624.2
MT-CO1
mitochondrially encoded cytochrome c oxidase I
chr11_-_842509 0.21 ENST00000322028.4
POLR2L
polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa
chr2_+_71163051 0.21 ENST00000412314.1
ATP6V1B1
ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1
chr16_-_2260834 0.21 ENST00000562360.1
ENST00000566018.1
BRICD5
BRICHOS domain containing 5
chr8_+_56014949 0.21 ENST00000327381.6
XKR4
XK, Kell blood group complex subunit-related family, member 4
chr12_-_49318715 0.21 ENST00000444214.2
FKBP11
FK506 binding protein 11, 19 kDa
chr22_+_41347363 0.21 ENST00000216225.8
RBX1
ring-box 1, E3 ubiquitin protein ligase
chr22_-_36013368 0.21 ENST00000442617.1
ENST00000397326.2
ENST00000397328.1
ENST00000451685.1
MB
myoglobin
chr1_+_79086088 0.21 ENST00000370751.5
ENST00000342282.3
IFI44L
interferon-induced protein 44-like
chr2_+_71162995 0.21 ENST00000234396.4
ATP6V1B1
ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1
chr17_-_15469590 0.21 ENST00000312127.2
CDRT1
CMT duplicated region transcript 1; Uncharacterized protein
chr2_-_74779744 0.20 ENST00000409249.1
LOXL3
lysyl oxidase-like 3
chr11_+_64052266 0.20 ENST00000539851.1
GPR137
G protein-coupled receptor 137
chr18_-_54318353 0.20 ENST00000590954.1
ENST00000540155.1
TXNL1
thioredoxin-like 1
chr2_+_27505260 0.20 ENST00000380075.2
ENST00000296098.4
TRIM54
tripartite motif containing 54
chr7_+_66800928 0.20 ENST00000430244.1
RP11-166O4.5
RP11-166O4.5
chr3_-_122512619 0.20 ENST00000383659.1
ENST00000306103.2
HSPBAP1
HSPB (heat shock 27kDa) associated protein 1
chr1_+_198608146 0.19 ENST00000367376.2
ENST00000352140.3
ENST00000594404.1
ENST00000598951.1
ENST00000530727.1
ENST00000442510.2
ENST00000367367.4
ENST00000348564.6
ENST00000367364.1
ENST00000413409.2
PTPRC
protein tyrosine phosphatase, receptor type, C
chr11_-_64901978 0.19 ENST00000294256.8
ENST00000377190.3
SYVN1
synovial apoptosis inhibitor 1, synoviolin
chr17_-_66287350 0.19 ENST00000580666.1
ENST00000583477.1
SLC16A6
solute carrier family 16, member 6
chr19_+_39759154 0.19 ENST00000331982.5
IFNL2
interferon, lambda 2
chr7_+_101928380 0.19 ENST00000536178.1
SH2B2
SH2B adaptor protein 2
chr16_+_69458537 0.19 ENST00000515314.1
ENST00000561792.1
ENST00000568237.1
CYB5B
cytochrome b5 type B (outer mitochondrial membrane)
chr17_-_26220366 0.19 ENST00000460380.2
ENST00000508862.1
ENST00000379102.3
ENST00000582441.1
LYRM9
RP1-66C13.4
LYR motif containing 9
Uncharacterized protein
chr2_+_239756671 0.19 ENST00000448943.2
TWIST2
twist family bHLH transcription factor 2
chr18_-_54305658 0.19 ENST00000586262.1
ENST00000217515.6
TXNL1
thioredoxin-like 1
chrX_+_70443050 0.19 ENST00000361726.6
GJB1
gap junction protein, beta 1, 32kDa
chr12_+_25348186 0.19 ENST00000555711.1
ENST00000556885.1
ENST00000554266.1
ENST00000556351.1
ENST00000556927.1
ENST00000556402.1
ENST00000553788.1
LYRM5
LYR motif containing 5
chr12_-_57443886 0.18 ENST00000300119.3
MYO1A
myosin IA
chr11_-_64901900 0.18 ENST00000526060.1
ENST00000307289.6
ENST00000528487.1
SYVN1
synovial apoptosis inhibitor 1, synoviolin
chr8_+_74206829 0.18 ENST00000240285.5
RDH10
retinol dehydrogenase 10 (all-trans)
chr20_-_50418947 0.18 ENST00000371539.3
SALL4
spalt-like transcription factor 4
chr20_-_50419055 0.18 ENST00000217086.4
SALL4
spalt-like transcription factor 4
chr5_-_78281603 0.18 ENST00000264914.4
ARSB
arylsulfatase B
chr14_+_103566665 0.18 ENST00000559116.1
EXOC3L4
exocyst complex component 3-like 4
chr16_+_30210552 0.18 ENST00000338971.5
SULT1A3
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
chr19_-_44285401 0.17 ENST00000262888.3
KCNN4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr4_+_166300084 0.17 ENST00000402744.4
CPE
carboxypeptidase E
chr5_-_66942617 0.17 ENST00000507298.1
RP11-83M16.5
RP11-83M16.5
chr17_-_7145106 0.17 ENST00000577035.1
GABARAP
GABA(A) receptor-associated protein
chr7_+_26438187 0.17 ENST00000439120.1
ENST00000430548.1
ENST00000421862.1
ENST00000449537.1
ENST00000420774.1
ENST00000418758.2
AC004540.5
AC004540.5
chr1_+_228395755 0.17 ENST00000284548.11
ENST00000570156.2
ENST00000422127.1
ENST00000366707.4
ENST00000366709.4
OBSCN
obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
chr5_+_43192311 0.17 ENST00000326035.2
NIM1
NIM1 serine/threonine protein kinase
chr1_-_146697185 0.17 ENST00000533174.1
ENST00000254090.4
FMO5
flavin containing monooxygenase 5
chr18_+_3450161 0.17 ENST00000551402.1
ENST00000577543.1
TGIF1
TGFB-induced factor homeobox 1
chr22_+_17082732 0.17 ENST00000558085.2
ENST00000592918.1
ENST00000400593.2
ENST00000592107.1
ENST00000426585.1
ENST00000591299.1
TPTEP1
transmembrane phosphatase with tensin homology pseudogene 1
chr6_+_88106840 0.17 ENST00000369570.4
C6orf164
chromosome 6 open reading frame 164
chr5_-_133968529 0.17 ENST00000402673.2
SAR1B
SAR1 homolog B (S. cerevisiae)
chr13_+_76413852 0.16 ENST00000533809.2
LMO7
LIM domain 7
chr16_+_29471210 0.16 ENST00000360423.7
SULT1A4
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4
chr1_+_186798073 0.16 ENST00000367466.3
ENST00000442353.2
PLA2G4A
phospholipase A2, group IVA (cytosolic, calcium-dependent)
chr18_+_3449695 0.16 ENST00000343820.5
TGIF1
TGFB-induced factor homeobox 1
chr14_+_24458021 0.16 ENST00000397071.1
ENST00000559411.1
ENST00000335125.6
DHRS4L2
dehydrogenase/reductase (SDR family) member 4 like 2
chr14_+_24458123 0.16 ENST00000545240.1
ENST00000382755.4
DHRS4L2
dehydrogenase/reductase (SDR family) member 4 like 2
chrX_-_48931648 0.16 ENST00000376386.3
ENST00000376390.4
PRAF2
PRA1 domain family, member 2
chr7_-_156803329 0.16 ENST00000252971.6
MNX1
motor neuron and pancreas homeobox 1
chrX_+_133930798 0.16 ENST00000414371.2
FAM122C
family with sequence similarity 122C
chr13_-_34250861 0.15 ENST00000445227.1
ENST00000454681.2
RP11-141M1.3
RP11-141M1.3
chr10_+_94608245 0.15 ENST00000443748.2
ENST00000260762.6
EXOC6
exocyst complex component 6
chr11_-_64052111 0.15 ENST00000394532.3
ENST00000394531.3
ENST00000309032.3
BAD
BCL2-associated agonist of cell death
chr19_-_10121144 0.15 ENST00000264828.3
COL5A3
collagen, type V, alpha 3
chr19_-_4182530 0.15 ENST00000601571.1
ENST00000601488.1
ENST00000305232.6
ENST00000381935.3
ENST00000337491.2
SIRT6
sirtuin 6
chr1_-_65533390 0.15 ENST00000448344.1
RP4-535B20.1
RP4-535B20.1
chr1_-_35450897 0.15 ENST00000373337.3
ZMYM6NB
ZMYM6 neighbor
chr19_+_35741466 0.15 ENST00000599658.1
LSR
lipolysis stimulated lipoprotein receptor
chr19_+_49375649 0.15 ENST00000200453.5
PPP1R15A
protein phosphatase 1, regulatory subunit 15A
chr16_+_30006615 0.15 ENST00000563197.1
INO80E
INO80 complex subunit E
chr12_-_62653903 0.15 ENST00000552075.1
FAM19A2
family with sequence similarity 19 (chemokine (C-C motif)-like), member A2
chr11_+_67776012 0.15 ENST00000539229.1
ALDH3B1
aldehyde dehydrogenase 3 family, member B1
chr2_-_36779411 0.15 ENST00000406220.1
AC007401.2
Uncharacterized protein
chr8_+_71485681 0.14 ENST00000391684.1
AC120194.1
AC120194.1
chr1_-_151119087 0.14 ENST00000341697.3
ENST00000368914.3
SEMA6C
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C
chr4_-_16228120 0.14 ENST00000405303.2
TAPT1
transmembrane anterior posterior transformation 1
chr8_+_99076509 0.14 ENST00000318528.3
C8orf47
chromosome 8 open reading frame 47
chr16_-_57831676 0.14 ENST00000465878.2
ENST00000539578.1
ENST00000561524.1
KIFC3
kinesin family member C3
chr14_+_63671105 0.14 ENST00000316754.3
RHOJ
ras homolog family member J
chr15_-_48937884 0.14 ENST00000560355.1
FBN1
fibrillin 1
chr10_+_5135981 0.14 ENST00000380554.3
AKR1C3
aldo-keto reductase family 1, member C3
chr14_-_23299009 0.14 ENST00000488800.1
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chrX_-_74145273 0.14 ENST00000055682.6
KIAA2022
KIAA2022
chr1_+_205473720 0.14 ENST00000429964.2
ENST00000506784.1
ENST00000360066.2
CDK18
cyclin-dependent kinase 18
chr5_-_139930713 0.14 ENST00000602657.1
SRA1
steroid receptor RNA activator 1
chrX_-_153200676 0.14 ENST00000464845.1
NAA10
N(alpha)-acetyltransferase 10, NatA catalytic subunit
chr2_+_33661382 0.14 ENST00000402538.3
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr19_-_4182497 0.13 ENST00000597896.1
SIRT6
sirtuin 6
chr20_+_61299155 0.13 ENST00000451793.1
SLCO4A1
solute carrier organic anion transporter family, member 4A1
chr4_+_110736659 0.13 ENST00000394631.3
ENST00000226796.6
GAR1
GAR1 ribonucleoprotein
chr3_+_187461442 0.13 ENST00000450760.1
RP11-211G3.2
RP11-211G3.2
chr8_+_38243821 0.13 ENST00000519476.2
LETM2
leucine zipper-EF-hand containing transmembrane protein 2
chr3_+_50388126 0.13 ENST00000425346.1
ENST00000424512.1
ENST00000232508.5
ENST00000418577.1
ENST00000606589.1
CYB561D2
XXcos-LUCA11.5
cytochrome b561 family, member D2
Uncharacterized protein
chr1_+_104104379 0.13 ENST00000435302.1
AMY2B
amylase, alpha 2B (pancreatic)
chr20_-_3996036 0.13 ENST00000336095.6
RNF24
ring finger protein 24
chr14_+_23299088 0.13 ENST00000355151.5
ENST00000397496.3
ENST00000555345.1
ENST00000432849.3
ENST00000553711.1
ENST00000556465.1
ENST00000397505.2
ENST00000557221.1
ENST00000311892.6
ENST00000556840.1
ENST00000555536.1
MRPL52
mitochondrial ribosomal protein L52
chr1_+_231114795 0.13 ENST00000310256.2
ENST00000366658.2
ENST00000450711.1
ENST00000435927.1
ARV1
ARV1 homolog (S. cerevisiae)
chr4_-_105416039 0.13 ENST00000394767.2
CXXC4
CXXC finger protein 4
chr5_-_139283982 0.13 ENST00000340391.3
NRG2
neuregulin 2
chr1_+_95616933 0.13 ENST00000604203.1
RP11-57H12.6
TMEM56-RWDD3 readthrough
chr6_+_17600576 0.13 ENST00000259963.3
FAM8A1
family with sequence similarity 8, member A1
chr20_+_36405665 0.13 ENST00000373469.1
CTNNBL1
catenin, beta like 1
chr18_+_54814288 0.13 ENST00000585477.1
BOD1L2
biorientation of chromosomes in cell division 1-like 2
chr6_-_84418841 0.13 ENST00000369694.2
ENST00000195649.6
SNAP91
synaptosomal-associated protein, 91kDa
chr4_-_149365827 0.13 ENST00000344721.4
NR3C2
nuclear receptor subfamily 3, group C, member 2
chr12_-_25348007 0.12 ENST00000354189.5
ENST00000545133.1
ENST00000554347.1
ENST00000395987.3
ENST00000320267.9
ENST00000395990.2
ENST00000537577.1
CASC1
cancer susceptibility candidate 1
chr7_-_25702669 0.12 ENST00000446840.1
AC003090.1
AC003090.1
chr9_-_35812140 0.12 ENST00000497810.1
ENST00000396638.2
ENST00000484764.1
SPAG8
sperm associated antigen 8
chr9_-_100459639 0.12 ENST00000375128.4
XPA
xeroderma pigmentosum, complementation group A
chr11_-_84028339 0.12 ENST00000398301.2
DLG2
discs, large homolog 2 (Drosophila)
chr8_+_99076750 0.12 ENST00000545282.1
C8orf47
chromosome 8 open reading frame 47
chr17_-_39156138 0.12 ENST00000391587.1
KRTAP3-2
keratin associated protein 3-2
chr19_-_39735646 0.12 ENST00000413851.2
IFNL3
interferon, lambda 3
chr4_+_24661479 0.12 ENST00000569621.1
RP11-496D24.2
RP11-496D24.2
chr11_-_73687997 0.12 ENST00000545212.1
UCP2
uncoupling protein 2 (mitochondrial, proton carrier)
chr11_-_84028180 0.12 ENST00000280241.8
DLG2
discs, large homolog 2 (Drosophila)
chrX_-_153775760 0.12 ENST00000440967.1
ENST00000393564.2
ENST00000369620.2
G6PD
glucose-6-phosphate dehydrogenase
chr4_-_175443943 0.12 ENST00000296522.6
HPGD
hydroxyprostaglandin dehydrogenase 15-(NAD)
chr9_+_125512019 0.12 ENST00000373684.1
ENST00000304720.2
OR1L6
olfactory receptor, family 1, subfamily L, member 6
chr6_-_84418860 0.12 ENST00000521743.1
SNAP91
synaptosomal-associated protein, 91kDa
chr16_-_30582888 0.12 ENST00000563707.1
ENST00000567855.1
ZNF688
zinc finger protein 688
chr8_-_8318847 0.12 ENST00000521218.1
CTA-398F10.2
CTA-398F10.2
chr2_-_71454185 0.11 ENST00000244221.8
PAIP2B
poly(A) binding protein interacting protein 2B
chr3_+_185080908 0.11 ENST00000265026.3
MAP3K13
mitogen-activated protein kinase kinase kinase 13
chr2_+_223916862 0.11 ENST00000604125.1
KCNE4
potassium voltage-gated channel, Isk-related family, member 4
chr15_-_55562582 0.11 ENST00000396307.2
RAB27A
RAB27A, member RAS oncogene family
chr3_+_51575596 0.11 ENST00000409535.2
RAD54L2
RAD54-like 2 (S. cerevisiae)
chr15_-_37392086 0.11 ENST00000561208.1
MEIS2
Meis homeobox 2
chrX_+_129473916 0.11 ENST00000545805.1
ENST00000543953.1
ENST00000218197.5
SLC25A14
solute carrier family 25 (mitochondrial carrier, brain), member 14
chr2_+_97202480 0.11 ENST00000357485.3
ARID5A
AT rich interactive domain 5A (MRF1-like)
chr4_+_42399856 0.11 ENST00000319234.4
SHISA3
shisa family member 3
chr11_+_89867803 0.11 ENST00000321955.4
ENST00000525171.1
ENST00000375944.3
NAALAD2
N-acetylated alpha-linked acidic dipeptidase 2
chr16_-_57219926 0.11 ENST00000566584.1
ENST00000566481.1
ENST00000566077.1
ENST00000564108.1
ENST00000565458.1
ENST00000566681.1
ENST00000567439.1
FAM192A
family with sequence similarity 192, member A
chr1_+_111889212 0.11 ENST00000369737.4
PIFO
primary cilia formation
chr8_-_6420759 0.11 ENST00000523120.1
ANGPT2
angiopoietin 2
chr7_+_1272522 0.11 ENST00000316333.8
UNCX
UNC homeobox
chr19_-_44143939 0.11 ENST00000222374.2
CADM4
cell adhesion molecule 4
chr14_+_100150622 0.10 ENST00000261835.3
CYP46A1
cytochrome P450, family 46, subfamily A, polypeptide 1
chr3_+_150804676 0.10 ENST00000474524.1
ENST00000273432.4
MED12L
mediator complex subunit 12-like
chr2_+_118846008 0.10 ENST00000245787.4
INSIG2
insulin induced gene 2
chr17_-_27418537 0.10 ENST00000408971.2
TIAF1
TGFB1-induced anti-apoptotic factor 1
chr9_-_35812236 0.10 ENST00000340291.2
SPAG8
sperm associated antigen 8
chr15_-_81195510 0.10 ENST00000561295.1
RP11-351M8.1
Uncharacterized protein
chr20_-_50418972 0.10 ENST00000395997.3
SALL4
spalt-like transcription factor 4
chr10_-_73848531 0.10 ENST00000373109.2
SPOCK2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr5_+_139505520 0.10 ENST00000333305.3
IGIP
IgA-inducing protein
chr11_+_18287721 0.10 ENST00000356524.4
SAA1
serum amyloid A1
chr6_+_138188551 0.10 ENST00000237289.4
ENST00000433680.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr18_+_66465475 0.10 ENST00000581520.1
CCDC102B
coiled-coil domain containing 102B
chr10_-_73848764 0.10 ENST00000317376.4
ENST00000412663.1
SPOCK2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2

Network of associatons between targets according to the STRING database.

First level regulatory network of TGIF1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0045362 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.2 1.3 GO:0070295 renal water absorption(GO:0070295)
0.2 0.6 GO:0043311 regulation of eosinophil degranulation(GO:0043309) positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.1 0.5 GO:0015688 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.1 0.5 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.1 0.4 GO:2000863 positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
0.1 0.3 GO:0003245 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.1 0.4 GO:0050928 negative regulation of positive chemotaxis(GO:0050928)
0.1 0.3 GO:0021569 rhombomere 3 development(GO:0021569)
0.1 0.5 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.1 0.2 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.1 0.2 GO:0052314 phytoalexin metabolic process(GO:0052314)
0.1 0.3 GO:0007525 somatic muscle development(GO:0007525)
0.1 0.2 GO:0030070 insulin processing(GO:0030070)
0.1 0.2 GO:0046882 negative regulation of B cell differentiation(GO:0045578) negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.1 0.3 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.1 0.2 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.1 0.1 GO:0014724 regulation of twitch skeletal muscle contraction(GO:0014724)
0.1 0.2 GO:2000854 positive regulation of corticosterone secretion(GO:2000854)
0.1 0.2 GO:0052151 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139)
0.1 0.8 GO:0060050 positive regulation of protein glycosylation(GO:0060050)
0.1 0.2 GO:1903526 negative regulation of membrane tubulation(GO:1903526)
0.0 0.1 GO:0060734 regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734)
0.0 0.1 GO:2000224 sesquiterpenoid metabolic process(GO:0006714) sesquiterpenoid catabolic process(GO:0016107) farnesol metabolic process(GO:0016487) farnesol catabolic process(GO:0016488) regulation of testosterone biosynthetic process(GO:2000224)
0.0 0.1 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.0 0.4 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.1 GO:0017198 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.0 0.1 GO:0034147 regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) tolerance induction to lipopolysaccharide(GO:0072573) negative regulation of CD40 signaling pathway(GO:2000349)
0.0 0.2 GO:0036309 protein localization to M-band(GO:0036309)
0.0 0.1 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.0 0.1 GO:0034085 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0 0.2 GO:0002378 immunoglobulin biosynthetic process(GO:0002378) hematopoietic stem cell migration(GO:0035701)
0.0 0.1 GO:0021571 rhombomere 5 development(GO:0021571)
0.0 0.1 GO:0061580 colon epithelial cell migration(GO:0061580)
0.0 0.2 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.1 GO:0090274 regulation of somatostatin secretion(GO:0090273) positive regulation of somatostatin secretion(GO:0090274)
0.0 0.1 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) negative regulation of neuromuscular junction development(GO:1904397)
0.0 0.1 GO:0070408 carbamoyl phosphate metabolic process(GO:0070408) carbamoyl phosphate biosynthetic process(GO:0070409) response to ammonia(GO:1903717) cellular response to ammonia(GO:1903718)
0.0 0.1 GO:0031296 positive regulation of germinal center formation(GO:0002636) B cell costimulation(GO:0031296)
0.0 0.1 GO:1904274 tricellular tight junction assembly(GO:1904274)
0.0 0.2 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.0 0.4 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.0 0.5 GO:0051601 exocyst localization(GO:0051601)
0.0 0.1 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.0 0.2 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.0 0.2 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.1 GO:0006480 N-terminal protein amino acid methylation(GO:0006480)
0.0 0.1 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.0 0.3 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.0 0.3 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.2 GO:0046541 saliva secretion(GO:0046541)
0.0 0.1 GO:0032223 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.0 0.1 GO:0035582 sequestering of BMP in extracellular matrix(GO:0035582)
0.0 0.1 GO:0032380 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0 0.1 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.2 GO:0060431 primary lung bud formation(GO:0060431)
0.0 0.1 GO:1901073 N-acetylglucosamine biosynthetic process(GO:0006045) glucosamine-containing compound biosynthetic process(GO:1901073)
0.0 0.3 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.0 0.3 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.0 0.1 GO:0097527 necroptotic signaling pathway(GO:0097527)
0.0 0.1 GO:1904798 positive regulation of core promoter binding(GO:1904798)
0.0 0.1 GO:0023021 termination of signal transduction(GO:0023021)
0.0 0.0 GO:0070175 positive regulation of enamel mineralization(GO:0070175)
0.0 0.1 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.7 GO:0015988 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988)
0.0 0.0 GO:0043438 acetoacetic acid metabolic process(GO:0043438)
0.0 0.1 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.1 GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
0.0 0.1 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.0 0.1 GO:0043324 eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.0 0.1 GO:0034287 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) response to chlorate(GO:0010157) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.0 0.1 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.0 0.2 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.1 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.0 0.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.1 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.2 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.2 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.1 GO:0000432 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432)
0.0 0.5 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.0 0.2 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.3 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.3 GO:0015868 purine ribonucleotide transport(GO:0015868)
0.0 0.1 GO:0003096 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.0 0.0 GO:0097065 anterior head development(GO:0097065) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744)
0.0 0.1 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.1 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0 0.5 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.0 0.1 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 0.1 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.4 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.1 0.4 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.1 0.3 GO:0031933 telomeric heterochromatin(GO:0031933)
0.1 0.2 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
0.1 0.4 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.1 0.2 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.6 GO:0043219 lateral loop(GO:0043219)
0.0 0.4 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.2 GO:0031415 NatA complex(GO:0031415)
0.0 0.1 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.0 0.1 GO:0090661 box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.0 0.1 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.1 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.1 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.0 0.2 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.1 GO:0020005 symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005)
0.0 0.7 GO:0000145 exocyst(GO:0000145)
0.0 0.3 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.1 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.1 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.1 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.3 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.4 GO:0044224 juxtaparanode region of axon(GO:0044224)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 GO:0015254 glycerol channel activity(GO:0015254)
0.2 0.7 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.2 0.6 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.1 0.4 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.1 0.5 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.1 0.3 GO:0032129 histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969)
0.1 0.3 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.0 0.1 GO:0047017 geranylgeranyl reductase activity(GO:0045550) prostaglandin-F synthase activity(GO:0047017)
0.0 0.4 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 1.1 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.3 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.0 0.1 GO:1990190 peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.0 0.1 GO:0031859 platelet activating factor receptor binding(GO:0031859)
0.0 0.3 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.2 GO:0047685 amine sulfotransferase activity(GO:0047685)
0.0 0.2 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.2 GO:0034711 inhibin binding(GO:0034711)
0.0 0.4 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 0.1 GO:0004556 alpha-amylase activity(GO:0004556)
0.0 0.5 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.0 0.2 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.0 0.1 GO:0005018 platelet-derived growth factor alpha-receptor activity(GO:0005018)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.1 GO:0000773 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.0 0.1 GO:0035643 L-DOPA receptor activity(GO:0035643) L-DOPA binding(GO:0072544)
0.0 0.1 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.0 0.1 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.0 0.3 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.2 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.1 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.0 0.1 GO:0008761 UDP-N-acetylglucosamine 2-epimerase activity(GO:0008761) N-acylmannosamine kinase activity(GO:0009384)
0.0 0.1 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0 0.2 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.5 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.1 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
0.0 0.1 GO:0004088 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.0 0.1 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.0 0.0 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
0.0 0.1 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.0 0.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.1 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.0 0.1 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.1 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.0 0.1 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.0 0.3 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.1 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.2 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.1 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.0 0.1 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.0 0.1 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.0 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.0 0.2 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.2 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.1 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.1 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.1 GO:0042015 interleukin-20 binding(GO:0042015)
0.0 0.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.5 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.1 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.0 0.1 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 0.0 GO:0003863 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.0 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.1 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.5 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 0.4 PID LPA4 PATHWAY LPA4-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.2 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.6 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.6 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.5 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.3 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.7 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.8 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.4 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.7 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.3 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules