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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for THRA_RXRB

Z-value: 0.71

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Transcription factors associated with THRA_RXRB

Gene Symbol Gene ID Gene Info
ENSG00000126351.8 thyroid hormone receptor alpha
ENSG00000204231.6 retinoid X receptor beta

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RXRBhg19_v2_chr6_-_33168391_33168465-0.642.3e-03Click!
THRAhg19_v2_chr17_+_38219063_382191540.174.8e-01Click!

Activity profile of THRA_RXRB motif

Sorted Z-values of THRA_RXRB motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_162887556 1.43 ENST00000393915.4
ENST00000432118.2
ENST00000358715.3
hyaluronan-mediated motility receptor (RHAMM)
chr12_+_102513950 1.11 ENST00000378128.3
ENST00000327680.2
ENST00000541394.1
ENST00000543784.1
PARP1 binding protein
chr1_-_150693318 1.06 ENST00000442853.1
ENST00000368995.4
ENST00000368993.2
ENST00000361824.2
ENST00000322343.7
HORMA domain containing 1
chr12_+_41221794 1.02 ENST00000547849.1
contactin 1
chrX_-_30327495 0.94 ENST00000453287.1
nuclear receptor subfamily 0, group B, member 1
chr1_-_150693305 0.92 ENST00000368987.1
HORMA domain containing 1
chr12_+_41221975 0.92 ENST00000552913.1
contactin 1
chr12_+_57854274 0.85 ENST00000528432.1
GLI family zinc finger 1
chr19_+_49467232 0.84 ENST00000599784.1
ENST00000594305.1
CTD-2639E6.9
chr12_+_102514019 0.82 ENST00000537257.1
ENST00000358383.5
ENST00000392911.2
PARP1 binding protein
chr5_+_172332220 0.72 ENST00000518247.1
ENST00000326654.2
endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1
chr9_-_114245938 0.71 ENST00000602447.1
KIAA0368
chr6_-_89673280 0.66 ENST00000369475.3
ENST00000369485.4
ENST00000538899.1
ENST00000265607.6
RNA guanylyltransferase and 5'-phosphatase
chr9_-_114246332 0.60 ENST00000602978.1
KIAA0368
chr17_-_74489215 0.58 ENST00000585701.1
ENST00000591192.1
ENST00000589526.1
rhomboid 5 homolog 2 (Drosophila)
chr10_+_26986582 0.53 ENST00000376215.5
ENST00000376203.5
prenyl (decaprenyl) diphosphate synthase, subunit 1
chr1_-_244006528 0.52 ENST00000336199.5
ENST00000263826.5
v-akt murine thymoma viral oncogene homolog 3
chr14_-_102552659 0.49 ENST00000441629.2
heat shock protein 90kDa alpha (cytosolic), class A member 1
chr7_+_94536898 0.48 ENST00000433360.1
ENST00000340694.4
ENST00000424654.1
protein phosphatase 1, regulatory subunit 9A
chr14_-_58893832 0.46 ENST00000556007.2
translocase of inner mitochondrial membrane 9 homolog (yeast)
chr19_+_32836499 0.46 ENST00000311921.4
ENST00000544431.1
ENST00000355898.5
zinc finger protein 507
chr16_-_2379688 0.46 ENST00000567910.1
ATP-binding cassette, sub-family A (ABC1), member 3
chr10_+_76586348 0.45 ENST00000372724.1
ENST00000287239.4
ENST00000372714.1
K(lysine) acetyltransferase 6B
chr8_-_99954788 0.45 ENST00000523601.1
serine/threonine kinase 3
chr1_+_45212051 0.41 ENST00000372222.3
kinesin family member 2C
chr5_-_162887071 0.40 ENST00000302764.4
NudC domain containing 2
chr17_+_48046538 0.40 ENST00000240306.3
distal-less homeobox 4
chr17_-_36105009 0.39 ENST00000560016.1
ENST00000427275.2
ENST00000561193.1
HNF1 homeobox B
chr12_-_102513843 0.39 ENST00000551744.2
ENST00000552283.1
nucleoporin 37kDa
chr9_+_36572851 0.39 ENST00000298048.2
ENST00000538311.1
ENST00000536987.1
ENST00000545008.1
ENST00000536860.1
ENST00000536329.1
ENST00000541717.1
ENST00000543751.1
maternal embryonic leucine zipper kinase
chr14_-_104028595 0.38 ENST00000337322.4
ENST00000445922.2
BCL2-associated athanogene 5
chr6_+_35773070 0.38 ENST00000373853.1
ENST00000360215.1
lipoma HMGIC fusion partner-like 5
chr12_-_96184913 0.38 ENST00000538383.1
netrin 4
chr2_-_230786619 0.37 ENST00000389045.3
ENST00000409677.1
thyroid hormone receptor interactor 12
chr12_-_96184533 0.36 ENST00000343702.4
ENST00000344911.4
netrin 4
chr17_-_15496722 0.36 ENST00000472534.1
CMT1A duplicated region transcript 1
chr6_+_31783291 0.35 ENST00000375651.5
ENST00000608703.1
ENST00000458062.2
heat shock 70kDa protein 1A
chr18_+_32558380 0.35 ENST00000588349.2
microtubule-associated protein, RP/EB family, member 2
chr7_+_128431444 0.35 ENST00000459946.1
ENST00000378685.4
ENST00000464832.1
ENST00000472049.1
ENST00000488925.1
coiled-coil domain containing 136
chr2_-_179315490 0.35 ENST00000487082.1
protein kinase, interferon-inducible double stranded RNA dependent activator
chr2_-_230786679 0.34 ENST00000543084.1
ENST00000343290.5
ENST00000389044.4
ENST00000283943.5
thyroid hormone receptor interactor 12
chr19_-_10450328 0.34 ENST00000160262.5
intercellular adhesion molecule 3
chr19_-_39826639 0.34 ENST00000602185.1
ENST00000598034.1
ENST00000601387.1
ENST00000595636.1
ENST00000253054.8
ENST00000594700.1
ENST00000597595.1
glia maturation factor, gamma
chr3_+_10068095 0.34 ENST00000287647.3
ENST00000383807.1
ENST00000383806.1
ENST00000419585.1
Fanconi anemia, complementation group D2
chr1_-_205719295 0.34 ENST00000367142.4
nuclear casein kinase and cyclin-dependent kinase substrate 1
chr8_+_98881268 0.34 ENST00000254898.5
ENST00000524308.1
ENST00000522025.2
matrilin 2
chr3_-_194207388 0.33 ENST00000457986.1
ATPase type 13A3
chr2_-_179315453 0.33 ENST00000432031.2
protein kinase, interferon-inducible double stranded RNA dependent activator
chr14_-_58893876 0.33 ENST00000555097.1
ENST00000555404.1
translocase of inner mitochondrial membrane 9 homolog (yeast)
chr1_+_229440129 0.33 ENST00000366688.3
S-phase response (cyclin related)
chr1_+_41204506 0.33 ENST00000525290.1
ENST00000530965.1
ENST00000416859.2
ENST00000308733.5
nuclear transcription factor Y, gamma
chr1_+_45212074 0.33 ENST00000372217.1
kinesin family member 2C
chr16_+_85942594 0.32 ENST00000566369.1
interferon regulatory factor 8
chr3_-_15374659 0.32 ENST00000426925.1
SH3-domain binding protein 5 (BTK-associated)
chr14_+_88852059 0.31 ENST00000045347.7
spermatogenesis associated 7
chr2_-_179315786 0.31 ENST00000457633.1
ENST00000438687.3
ENST00000325748.4
protein kinase, interferon-inducible double stranded RNA dependent activator
chr12_-_95510743 0.31 ENST00000551521.1
FYVE, RhoGEF and PH domain containing 6
chr11_+_111896090 0.31 ENST00000393051.1
dihydrolipoamide S-acetyltransferase
chr10_-_33625154 0.31 ENST00000265371.4
neuropilin 1
chr19_-_10450287 0.31 ENST00000589261.1
ENST00000590569.1
ENST00000589580.1
ENST00000589249.1
intercellular adhesion molecule 3
chr8_+_27632047 0.30 ENST00000397418.2
establishment of sister chromatid cohesion N-acetyltransferase 2
chr8_+_27632083 0.30 ENST00000519637.1
establishment of sister chromatid cohesion N-acetyltransferase 2
chr7_-_108097144 0.30 ENST00000418239.1
neuronal cell adhesion molecule
chrX_+_67913471 0.30 ENST00000374597.3
StAR-related lipid transfer (START) domain containing 8
chr3_+_87276407 0.29 ENST00000471660.1
ENST00000263780.4
ENST00000494980.1
charged multivesicular body protein 2B
chr8_-_18666360 0.29 ENST00000286485.8
pleckstrin and Sec7 domain containing 3
chr3_-_45957088 0.29 ENST00000539217.1
leucine zipper transcription factor-like 1
chr10_+_11784360 0.29 ENST00000379215.4
ENST00000420401.1
enoyl CoA hydratase domain containing 3
chr22_+_31277661 0.29 ENST00000454145.1
ENST00000453621.1
ENST00000431368.1
ENST00000535268.1
oxysterol binding protein 2
chr15_-_80215984 0.29 ENST00000485386.1
ENST00000479961.1
suppressor of tumorigenicity 20
ST20-MTHFS readthrough
chr17_+_27369918 0.29 ENST00000323372.4
pipecolic acid oxidase
chrX_+_9431324 0.29 ENST00000407597.2
ENST00000424279.1
ENST00000536365.1
ENST00000441088.1
ENST00000380961.1
ENST00000415293.1
transducin (beta)-like 1X-linked
chr11_-_117699413 0.28 ENST00000528014.1
FXYD domain containing ion transport regulator 2
chr12_-_88535747 0.28 ENST00000309041.7
centrosomal protein 290kDa
chr15_+_48413169 0.28 ENST00000341459.3
ENST00000482911.2
solute carrier family 24 (sodium/potassium/calcium exchanger), member 5
chr14_-_104029013 0.28 ENST00000299204.4
ENST00000557666.1
BCL2-associated athanogene 5
chr14_-_82000140 0.28 ENST00000555824.1
ENST00000557372.1
ENST00000336735.4
sel-1 suppressor of lin-12-like (C. elegans)
chr7_+_94536514 0.28 ENST00000413325.1
protein phosphatase 1, regulatory subunit 9A
chr12_-_124873357 0.28 ENST00000448614.1
nuclear receptor corepressor 2
chr2_+_230787201 0.27 ENST00000283946.3
F-box protein 36
chr3_-_179322416 0.27 ENST00000259038.2
mitochondrial ribosomal protein L47
chr11_-_795286 0.27 ENST00000533385.1
ENST00000527723.1
solute carrier family 25 (mitochondrial carrier: glutamate), member 22
chr10_+_75757863 0.27 ENST00000372755.3
ENST00000211998.4
ENST00000417648.2
vinculin
chr16_-_28192360 0.27 ENST00000570033.1
exportin 6
chr11_+_111896320 0.27 ENST00000531306.1
ENST00000537636.1
dihydrolipoamide S-acetyltransferase
chr12_+_52668394 0.26 ENST00000423955.2
keratin 86
chr6_+_64346386 0.26 ENST00000509330.1
PHD finger protein 3
chr17_-_38821373 0.25 ENST00000394052.3
keratin 222
chr5_+_170288856 0.25 ENST00000523189.1
RAN binding protein 17
chr14_+_71788096 0.25 ENST00000557151.1
signal-induced proliferation-associated 1 like 1
chr7_-_151433393 0.25 ENST00000492843.1
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
chr11_-_73720276 0.25 ENST00000348534.4
uncoupling protein 3 (mitochondrial, proton carrier)
chr20_+_19870167 0.25 ENST00000440354.2
Ras and Rab interactor 2
chr1_+_25071848 0.25 ENST00000374379.4
chloride intracellular channel 4
chr15_-_83315874 0.24 ENST00000569257.1
cytoplasmic polyadenylation element binding protein 1
chr17_-_58499766 0.24 ENST00000588898.1
ubiquitin specific peptidase 32
chr2_+_32853093 0.24 ENST00000448773.1
ENST00000317907.4
tetratricopeptide repeat domain 27
chr5_-_145483932 0.24 ENST00000311450.4
PLAC8-like 1
chr8_+_110552831 0.24 ENST00000530629.1
estrogen receptor binding site associated, antigen, 9
chr2_-_55459294 0.24 ENST00000407122.1
ENST00000406437.2
clathrin heavy chain linker domain containing 1
chr15_-_51914996 0.24 ENST00000251076.5
Dmx-like 2
chr8_-_53626974 0.23 ENST00000435644.2
ENST00000518710.1
ENST00000025008.5
ENST00000517963.1
RB1-inducible coiled-coil 1
chr5_+_145583156 0.23 ENST00000265271.5
RNA binding motif protein 27
chr9_-_72374848 0.23 ENST00000377200.5
ENST00000340434.4
ENST00000472967.2
protein prenyltransferase alpha subunit repeat containing 1
chr3_+_14989186 0.23 ENST00000435454.1
ENST00000323373.6
nuclear receptor subfamily 2, group C, member 2
chr7_-_151433342 0.23 ENST00000433631.2
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
chr9_+_131452239 0.23 ENST00000372688.4
ENST00000372686.5
SET nuclear oncogene
chr11_+_7618413 0.23 ENST00000528883.1
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr5_+_112849373 0.23 ENST00000161863.4
ENST00000515883.1
YTH domain containing 2
chr10_-_116164239 0.23 ENST00000419268.1
ENST00000304129.4
ENST00000545353.1
actin filament associated protein 1-like 2
chr4_+_48343339 0.23 ENST00000264313.6
SLAIN motif family, member 2
chr8_-_42698292 0.23 ENST00000529779.1
THAP domain containing, apoptosis associated protein 1
chr17_-_3595042 0.23 ENST00000552723.1
purinergic receptor P2X, ligand-gated ion channel, 5
chr8_+_104033296 0.23 ENST00000521514.1
ENST00000518738.1
ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1
chr16_-_72206034 0.23 ENST00000537465.1
ENST00000237353.10
polyamine modulated factor 1 binding protein 1
chr13_+_41635617 0.22 ENST00000542082.1
WW domain binding protein 4
chrX_+_114827818 0.22 ENST00000420625.2
plastin 3
chrX_+_135230712 0.22 ENST00000535737.1
four and a half LIM domains 1
chr11_-_73720122 0.22 ENST00000426995.2
uncoupling protein 3 (mitochondrial, proton carrier)
chr1_-_160231451 0.22 ENST00000495887.1
DDB1 and CUL4 associated factor 8
chr17_-_58469687 0.22 ENST00000590133.1
ubiquitin specific peptidase 32
chr10_+_99332198 0.22 ENST00000307518.5
ENST00000298808.5
ENST00000370655.1
ankyrin repeat domain 2 (stretch responsive muscle)
chr12_+_11905413 0.21 ENST00000545027.1
ets variant 6
chr3_+_164924716 0.21 ENST00000470138.1
ENST00000498616.1
RP11-85M11.2
chr2_-_55459437 0.21 ENST00000401408.1
clathrin heavy chain linker domain containing 1
chr3_-_195270162 0.21 ENST00000438848.1
ENST00000328432.3
protein phosphatase 1, regulatory (inhibitor) subunit 2
chr6_-_150039249 0.21 ENST00000543571.1
large tumor suppressor kinase 1
chr5_+_145583107 0.20 ENST00000506502.1
RNA binding motif protein 27
chr2_+_228190066 0.20 ENST00000436237.1
ENST00000443428.2
ENST00000418961.1
mitochondrial fission factor
chr20_+_56884752 0.20 ENST00000244040.3
RAB22A, member RAS oncogene family
chr12_+_95612006 0.20 ENST00000551311.1
ENST00000546445.1
vezatin, adherens junctions transmembrane protein
chr8_-_144413981 0.20 ENST00000522041.1
topoisomerase (DNA) I, mitochondrial
chr11_+_66624527 0.20 ENST00000393952.3
leucine rich repeat and fibronectin type III domain containing 4
chr2_+_86426478 0.20 ENST00000254644.8
ENST00000605125.1
ENST00000337109.4
ENST00000409180.1
mitochondrial ribosomal protein L35
chr3_+_9404526 0.20 ENST00000452837.2
ENST00000417036.1
ENST00000419437.1
ENST00000345094.3
ENST00000515662.2
THUMP domain containing 3
chr1_-_242612779 0.20 ENST00000427495.1
phospholipase D family, member 5
chr7_-_95064264 0.20 ENST00000536183.1
ENST00000433091.2
ENST00000222572.3
paraoxonase 2
chr3_+_12330560 0.19 ENST00000397026.2
peroxisome proliferator-activated receptor gamma
chr14_-_89021077 0.19 ENST00000556564.1
protein tyrosine phosphatase, non-receptor type 21
chr20_+_47538357 0.19 ENST00000371917.4
ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
chr11_+_122709200 0.19 ENST00000227348.4
cytotoxic and regulatory T cell molecule
chr13_-_76111945 0.19 ENST00000355801.4
ENST00000406936.3
COMM domain containing 6
chr15_-_30113676 0.19 ENST00000400011.2
tight junction protein 1
chrX_+_114827851 0.19 ENST00000539310.1
plastin 3
chr22_+_22764088 0.19 ENST00000390299.2
immunoglobulin lambda variable 1-40
chrX_-_10851762 0.19 ENST00000380785.1
ENST00000380787.1
midline 1 (Opitz/BBB syndrome)
chr16_-_74734742 0.18 ENST00000308807.7
ENST00000573267.1
mixed lineage kinase domain-like
chr20_+_42193856 0.18 ENST00000412111.1
ENST00000423407.3
serum/glucocorticoid regulated kinase 2
chr14_+_74551650 0.18 ENST00000554938.1
lin-52 homolog (C. elegans)
chr7_+_112090483 0.18 ENST00000403825.3
ENST00000429071.1
interferon-related developmental regulator 1
chr3_+_141105235 0.18 ENST00000503809.1
zinc finger and BTB domain containing 38
chr1_-_85156216 0.18 ENST00000342203.3
ENST00000370612.4
synovial sarcoma, X breakpoint 2 interacting protein
chr12_+_20963632 0.18 ENST00000540853.1
ENST00000261196.2
solute carrier organic anion transporter family, member 1B3
chr14_+_58765103 0.18 ENST00000355431.3
ENST00000348476.3
ENST00000395168.3
AT rich interactive domain 4A (RBP1-like)
chr11_-_27722021 0.18 ENST00000356660.4
ENST00000418212.1
ENST00000533246.1
brain-derived neurotrophic factor
chr1_+_179851893 0.18 ENST00000531630.2
torsin A interacting protein 1
chr3_+_179322573 0.17 ENST00000493866.1
ENST00000472629.1
ENST00000482604.1
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa
chr6_+_30131318 0.17 ENST00000376688.1
tripartite motif containing 15
chr9_-_88897426 0.17 ENST00000375991.4
ENST00000326094.4
iron-sulfur cluster assembly 1
chr14_-_55369525 0.17 ENST00000543643.2
ENST00000536224.2
ENST00000395514.1
ENST00000491895.2
GTP cyclohydrolase 1
chr1_-_203144941 0.17 ENST00000255416.4
myosin binding protein H
chr17_+_48046671 0.17 ENST00000505318.2
distal-less homeobox 4
chr22_+_23264766 0.17 ENST00000390331.2
immunoglobulin lambda constant 7
chr3_-_98241760 0.17 ENST00000507874.1
ENST00000502299.1
ENST00000508659.1
ENST00000510545.1
ENST00000511667.1
ENST00000394185.2
ENST00000394181.2
ENST00000508902.1
ENST00000341181.6
ENST00000437922.1
ENST00000394180.2
claudin domain containing 1
chr16_-_58328923 0.17 ENST00000567164.1
ENST00000219301.4
ENST00000569727.1
protease, serine, 54
chr14_+_57857262 0.17 ENST00000555166.1
ENST00000556492.1
ENST00000554703.1
N(alpha)-acetyltransferase 30, NatC catalytic subunit
chr9_-_127358087 0.17 ENST00000475178.1
nuclear receptor subfamily 6, group A, member 1
chr15_-_55881135 0.17 ENST00000302000.6
pygopus family PHD finger 1
chr2_+_197577841 0.16 ENST00000409270.1
coiled-coil domain containing 150
chr8_-_42698433 0.16 ENST00000345117.2
ENST00000254250.3
THAP domain containing, apoptosis associated protein 1
chr15_+_63050785 0.16 ENST00000472902.1
talin 2
chr16_-_58328870 0.16 ENST00000543437.1
protease, serine, 54
chr2_-_33824382 0.16 ENST00000238823.8
family with sequence similarity 98, member A
chr13_+_76123883 0.16 ENST00000377595.3
ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
chr12_+_53817633 0.16 ENST00000257863.4
ENST00000550311.1
ENST00000379791.3
anti-Mullerian hormone receptor, type II
chr12_+_20963647 0.16 ENST00000381545.3
solute carrier organic anion transporter family, member 1B3
chr15_-_93965805 0.16 ENST00000556708.1
RP11-164C12.2
chr22_+_39898391 0.16 ENST00000434364.1
mitochondrial elongation factor 1
chr3_+_127317945 0.16 ENST00000472731.1
minichromosome maintenance complex component 2
chr10_-_116164450 0.16 ENST00000369271.3
actin filament associated protein 1-like 2
chrX_-_39956656 0.16 ENST00000397354.3
ENST00000378444.4
BCL6 corepressor
chr14_+_88851874 0.16 ENST00000393545.4
ENST00000356583.5
ENST00000555401.1
ENST00000553885.1
spermatogenesis associated 7
chr5_+_142286887 0.16 ENST00000451259.1
Rho GTPase activating protein 26
chr12_-_114843889 0.15 ENST00000405440.2
T-box 5
chr12_-_122907091 0.15 ENST00000358808.2
ENST00000361654.4
ENST00000539080.1
ENST00000537178.1
CAP-GLY domain containing linker protein 1
chrX_-_13835461 0.15 ENST00000316715.4
ENST00000356942.5
glycoprotein M6B
chr21_+_17566643 0.15 ENST00000419952.1
ENST00000445461.2
long intergenic non-protein coding RNA 478
chr7_-_105319536 0.15 ENST00000477775.1
ataxin 7-like 1
chr10_+_99332529 0.15 ENST00000455090.1
ankyrin repeat domain 2 (stretch responsive muscle)
chr2_+_97454321 0.15 ENST00000540067.1
cyclin M4
chr21_+_34697258 0.15 ENST00000442071.1
ENST00000442357.2
interferon (alpha, beta and omega) receptor 1
chr17_-_18161870 0.15 ENST00000579294.1
ENST00000545457.2
ENST00000379450.4
ENST00000578558.1
flightless I homolog (Drosophila)
chr2_-_65593784 0.15 ENST00000443619.2
sprouty-related, EVH1 domain containing 2
chr11_-_77122928 0.14 ENST00000528203.1
ENST00000528592.1
ENST00000528633.1
ENST00000529248.1
p21 protein (Cdc42/Rac)-activated kinase 1
chr7_-_140179276 0.14 ENST00000443720.2
ENST00000255977.2
makorin ring finger protein 1
chr4_+_159122728 0.14 ENST00000505049.1
ENST00000505189.1
ENST00000511038.1
transmembrane protein 144
chr3_-_47205066 0.14 ENST00000412450.1
SET domain containing 2
chr18_+_12948000 0.14 ENST00000585730.1
ENST00000399892.2
ENST00000589446.1
ENST00000587761.1
SEH1-like (S. cerevisiae)
chr22_+_22681656 0.14 ENST00000390291.2
immunoglobulin lambda variable 1-50 (non-functional)
chr17_-_41132088 0.14 ENST00000591916.1
ENST00000451885.2
ENST00000454303.1
prostaglandin E synthase 3 (cytosolic)-like
PTGES3L-AARSD1 readthrough

Network of associatons between targets according to the STRING database.

First level regulatory network of THRA_RXRB

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0060629 regulation of homologous chromosome segregation(GO:0060629)
0.2 0.7 GO:0098507 polynucleotide 5' dephosphorylation(GO:0098507)
0.2 0.8 GO:0060032 notochord regression(GO:0060032)
0.2 0.8 GO:1904049 negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.1 1.9 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.1 0.7 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.1 0.3 GO:0060382 regulation of DNA strand elongation(GO:0060382)
0.1 0.7 GO:0061084 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
0.1 0.6 GO:0034421 post-translational protein acetylation(GO:0034421)
0.1 0.4 GO:0035565 regulation of pronephros size(GO:0035565) pronephric nephron tubule development(GO:0039020)
0.1 0.3 GO:1903567 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.1 0.5 GO:0043335 protein unfolding(GO:0043335)
0.1 0.4 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.1 0.3 GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
0.1 0.4 GO:0070426 positive regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070426) positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070434)
0.1 0.8 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.1 0.7 GO:1901314 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.1 1.0 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.1 0.3 GO:1902378 vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.1 0.2 GO:1901253 negative regulation of intracellular transport of viral material(GO:1901253)
0.1 0.7 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.1 0.4 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.1 0.2 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.1 0.9 GO:0030238 male sex determination(GO:0030238)
0.0 0.2 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.3 GO:0035441 cell migration involved in vasculogenesis(GO:0035441)
0.0 0.2 GO:2000230 negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.0 0.2 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.0 0.3 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.0 1.5 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.1 GO:0035508 positive regulation of myosin-light-chain-phosphatase activity(GO:0035508)
0.0 0.3 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.0 0.2 GO:0051066 dihydrobiopterin metabolic process(GO:0051066)
0.0 0.3 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.0 0.4 GO:0048022 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.0 0.3 GO:0019477 L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
0.0 0.3 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.0 0.8 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.2 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.0 0.1 GO:0010902 positive regulation of very-low-density lipoprotein particle remodeling(GO:0010902)
0.0 0.2 GO:0001827 inner cell mass cell fate commitment(GO:0001827) inner cell mass cellular morphogenesis(GO:0001828)
0.0 0.5 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.0 0.3 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.2 GO:1900063 regulation of peroxisome organization(GO:1900063)
0.0 0.6 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.0 2.0 GO:0010765 positive regulation of sodium ion transport(GO:0010765)
0.0 0.2 GO:0032971 regulation of muscle filament sliding(GO:0032971)
0.0 0.3 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244) negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
0.0 0.2 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.1 GO:0061386 closure of optic fissure(GO:0061386)
0.0 0.1 GO:1903028 positive regulation of opsonization(GO:1903028)
0.0 0.1 GO:0045829 negative regulation of isotype switching(GO:0045829)
0.0 0.4 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.3 GO:0036376 sodium ion export from cell(GO:0036376)
0.0 0.3 GO:0048793 pronephros development(GO:0048793)
0.0 0.1 GO:1902304 positive regulation of potassium ion export(GO:1902304)
0.0 0.2 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.0 0.3 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.2 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.4 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.4 GO:2000291 regulation of myoblast proliferation(GO:2000291)
0.0 0.1 GO:0009099 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.0 0.5 GO:1990845 adaptive thermogenesis(GO:1990845)
0.0 0.1 GO:0019557 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.0 0.5 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.1 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.0 0.2 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.1 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.0 0.3 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.2 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.0 0.4 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.2 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.3 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.0 0.3 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0 0.4 GO:0006853 carnitine shuttle(GO:0006853)
0.0 0.2 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.2 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.2 GO:0097354 protein prenylation(GO:0018342) prenylation(GO:0097354)
0.0 0.1 GO:0051012 microtubule sliding(GO:0051012)
0.0 0.1 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.0 0.2 GO:0002860 positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.0 0.1 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.0 0.3 GO:0044130 negative regulation of growth of symbiont in host(GO:0044130)
0.0 0.4 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.0 0.2 GO:0007144 female meiosis I(GO:0007144)
0.0 0.4 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 0.1 GO:0051014 actin filament severing(GO:0051014)
0.0 0.1 GO:0010166 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.0 0.2 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.1 GO:0090649 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.0 0.1 GO:0072719 cellular response to cisplatin(GO:0072719)
0.0 0.2 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.0 0.3 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.2 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.1 GO:0021993 initiation of neural tube closure(GO:0021993)
0.0 0.1 GO:1903286 regulation of potassium ion import(GO:1903286)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.1 0.6 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.1 0.5 GO:0097232 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.1 0.8 GO:0044326 dendritic spine neck(GO:0044326)
0.1 0.9 GO:0042788 polysomal ribosome(GO:0042788)
0.1 0.2 GO:0043291 RAVE complex(GO:0043291)
0.1 1.0 GO:0070578 RISC-loading complex(GO:0070578)
0.1 0.3 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.2 GO:0032279 asymmetric synapse(GO:0032279) symmetric synapse(GO:0032280)
0.0 0.2 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.0 2.0 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.6 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.1 GO:0035841 new growing cell tip(GO:0035841)
0.0 0.2 GO:0031417 NatC complex(GO:0031417)
0.0 0.5 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.1 GO:0045281 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.2 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.3 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.5 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 1.6 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.3 GO:0097443 sorting endosome(GO:0097443)
0.0 0.1 GO:0043614 multi-eIF complex(GO:0043614) translation preinitiation complex(GO:0070993) glial limiting end-foot(GO:0097451)
0.0 0.3 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.1 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 0.4 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.3 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.5 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.2 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.8 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.8 GO:0097546 ciliary base(GO:0097546)
0.0 0.2 GO:0031298 replication fork protection complex(GO:0031298)
0.0 0.5 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.0 0.4 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.1 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.1 GO:0060171 myosin I complex(GO:0045160) stereocilium membrane(GO:0060171)
0.0 0.3 GO:0005916 fascia adherens(GO:0005916)
0.0 0.0 GO:0005602 complement component C1 complex(GO:0005602)
0.0 0.1 GO:0005903 brush border(GO:0005903)
0.0 0.3 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.3 GO:0042571 immunoglobulin complex, circulating(GO:0042571)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0004651 polynucleotide 5'-phosphatase activity(GO:0004651)
0.2 0.6 GO:0016418 S-acetyltransferase activity(GO:0016418)
0.1 0.4 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.1 0.3 GO:0030272 5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
0.1 1.0 GO:0070883 pre-miRNA binding(GO:0070883)
0.1 0.6 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.1 0.6 GO:0043237 laminin-1 binding(GO:0043237)
0.1 0.5 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.1 0.7 GO:0019237 centromeric DNA binding(GO:0019237)
0.1 0.2 GO:0046573 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.1 0.2 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.1 0.4 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.1 GO:0019961 interferon binding(GO:0019961)
0.0 0.3 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0 0.7 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.5 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.5 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.0 0.1 GO:0051538 succinate dehydrogenase (ubiquinone) activity(GO:0008177) 3 iron, 4 sulfur cluster binding(GO:0051538)
0.0 0.2 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.0 0.5 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 1.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.4 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 0.3 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.9 GO:0000217 DNA secondary structure binding(GO:0000217)
0.0 0.2 GO:0008318 protein prenyltransferase activity(GO:0008318)
0.0 0.1 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.2 GO:0019238 cyclohydrolase activity(GO:0019238)
0.0 0.3 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.0 0.1 GO:0052654 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.0 0.2 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.2 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.2 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.2 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.7 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.1 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.0 0.2 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.1 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.0 0.2 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 0.3 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.1 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.2 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.1 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.8 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 0.1 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.3 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.6 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.3 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.3 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.2 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.3 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.3 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.4 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.3 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.1 GO:0034618 arginine binding(GO:0034618)
0.0 0.2 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 2.1 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.3 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.5 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.5 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.0 0.1 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 1.1 PID CERAMIDE PATHWAY Ceramide signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 2.0 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.5 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.3 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.6 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.7 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.6 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.3 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.7 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.7 REACTOME KINESINS Genes involved in Kinesins
0.0 0.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.7 REACTOME MRNA CAPPING Genes involved in mRNA Capping
0.0 1.4 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.6 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.9 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.3 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.1 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.3 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.4 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)