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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for TLX1_NFIC

Z-value: 1.46

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Transcription factors associated with TLX1_NFIC

Gene Symbol Gene ID Gene Info
TLX1
ENSG00000107807.8 T cell leukemia homeobox 1
NFIC
ENSG00000141905.13 nuclear factor I C

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TLX1hg19_v2_chr10_+_102891048_1028910780.651.9e-03Click!
NFIChg19_v2_chr19_+_3359561_33596810.371.1e-01Click!

Activity profile of TLX1_NFIC motif

Sorted Z-values of TLX1_NFIC motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr17_+_7344057 8.43 ENST00000575398.1
ENST00000575082.1
FGF11
fibroblast growth factor 11
chr1_-_153588765 8.20 ENST00000368701.1
ENST00000344616.2
S100A14
S100 calcium binding protein A14
chr1_-_153538292 7.87 ENST00000497140.1
ENST00000368708.3
S100A2
S100 calcium binding protein A2
chr1_-_153363452 6.78 ENST00000368732.1
ENST00000368733.3
S100A8
S100 calcium binding protein A8
chr14_+_24867992 5.79 ENST00000382554.3
NYNRIN
NYN domain and retroviral integrase containing
chr18_+_21529811 5.44 ENST00000588004.1
LAMA3
laminin, alpha 3
chr14_+_75746781 4.31 ENST00000555347.1
FOS
FBJ murine osteosarcoma viral oncogene homolog
chr7_+_22766766 3.66 ENST00000426291.1
ENST00000401651.1
ENST00000258743.5
ENST00000420258.2
ENST00000407492.1
ENST00000401630.3
ENST00000406575.1
IL6
interleukin 6 (interferon, beta 2)
chr1_+_79086088 3.54 ENST00000370751.5
ENST00000342282.3
IFI44L
interferon-induced protein 44-like
chr1_-_153538011 3.43 ENST00000368707.4
S100A2
S100 calcium binding protein A2
chr17_+_74372662 3.31 ENST00000591651.1
ENST00000545180.1
SPHK1
sphingosine kinase 1
chr22_+_40390930 3.19 ENST00000333407.6
FAM83F
family with sequence similarity 83, member F
chr3_+_38032216 3.01 ENST00000416303.1
VILL
villin-like
chr11_+_34663913 2.94 ENST00000532302.1
EHF
ets homologous factor
chr21_-_28217721 2.75 ENST00000284984.3
ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr12_-_15114603 2.70 ENST00000228945.4
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr14_+_85996507 2.70 ENST00000554746.1
FLRT2
fibronectin leucine rich transmembrane protein 2
chr14_+_85996471 2.67 ENST00000330753.4
FLRT2
fibronectin leucine rich transmembrane protein 2
chr1_-_153588334 2.65 ENST00000476873.1
S100A14
S100 calcium binding protein A14
chr7_+_143078652 2.61 ENST00000354434.4
ENST00000449423.2
ZYX
zyxin
chr11_+_34664014 2.61 ENST00000527935.1
EHF
ets homologous factor
chr17_-_74533963 2.47 ENST00000293230.5
CYGB
cytoglobin
chr2_+_113875466 2.47 ENST00000361779.3
ENST00000259206.5
ENST00000354115.2
IL1RN
interleukin 1 receptor antagonist
chr1_+_12538594 2.33 ENST00000543710.1
VPS13D
vacuolar protein sorting 13 homolog D (S. cerevisiae)
chr19_+_10397648 2.27 ENST00000340992.4
ENST00000393717.2
ICAM4
intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
chr7_+_143079000 2.22 ENST00000392910.2
ZYX
zyxin
chrX_+_99899180 2.18 ENST00000373004.3
SRPX2
sushi-repeat containing protein, X-linked 2
chr12_-_54813229 2.15 ENST00000293379.4
ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr11_-_111783919 2.08 ENST00000531198.1
ENST00000533879.1
CRYAB
crystallin, alpha B
chr12_-_15114191 2.01 ENST00000541380.1
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr19_+_10397621 1.95 ENST00000380770.3
ICAM4
intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
chr12_-_15114492 1.92 ENST00000541546.1
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr6_-_30043539 1.91 ENST00000376751.3
ENST00000244360.6
RNF39
ring finger protein 39
chr9_+_35673853 1.89 ENST00000378357.4
CA9
carbonic anhydrase IX
chr9_-_130617029 1.83 ENST00000373203.4
ENG
endoglin
chr6_-_28321971 1.81 ENST00000396838.2
ENST00000426434.1
ENST00000434036.1
ENST00000439628.1
ZSCAN31
zinc finger and SCAN domain containing 31
chr4_-_110723134 1.80 ENST00000510800.1
ENST00000512148.1
CFI
complement factor I
chr21_-_28215332 1.77 ENST00000517777.1
ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr19_-_49258606 1.76 ENST00000310160.3
FUT1
fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
chr18_+_33877654 1.72 ENST00000257209.4
ENST00000445677.1
ENST00000590592.1
ENST00000359247.4
FHOD3
formin homology 2 domain containing 3
chr10_+_5454505 1.72 ENST00000355029.4
NET1
neuroepithelial cell transforming 1
chr6_+_150920999 1.68 ENST00000367328.1
ENST00000367326.1
PLEKHG1
pleckstrin homology domain containing, family G (with RhoGef domain) member 1
chr22_+_41763274 1.66 ENST00000406644.3
TEF
thyrotrophic embryonic factor
chr15_-_40633101 1.64 ENST00000559313.1
C15orf52
chromosome 15 open reading frame 52
chr12_+_13349650 1.62 ENST00000256951.5
ENST00000431267.2
ENST00000542474.1
ENST00000544053.1
EMP1
epithelial membrane protein 1
chr9_-_130616915 1.61 ENST00000344849.3
ENG
endoglin
chr22_+_17082732 1.60 ENST00000558085.2
ENST00000592918.1
ENST00000400593.2
ENST00000592107.1
ENST00000426585.1
ENST00000591299.1
TPTEP1
transmembrane phosphatase with tensin homology pseudogene 1
chr17_-_39677971 1.55 ENST00000393976.2
KRT15
keratin 15
chr1_+_33231268 1.54 ENST00000373480.1
KIAA1522
KIAA1522
chr14_-_85996332 1.52 ENST00000380722.1
RP11-497E19.1
RP11-497E19.1
chr5_+_176784837 1.50 ENST00000408923.3
RGS14
regulator of G-protein signaling 14
chr1_+_79115503 1.47 ENST00000370747.4
ENST00000438486.1
ENST00000545124.1
IFI44
interferon-induced protein 44
chr8_-_80680078 1.46 ENST00000337919.5
ENST00000354724.3
HEY1
hes-related family bHLH transcription factor with YRPW motif 1
chr8_-_145701718 1.45 ENST00000377317.4
FOXH1
forkhead box H1
chr5_-_138861926 1.45 ENST00000510817.1
TMEM173
transmembrane protein 173
chr4_-_110723335 1.43 ENST00000394634.2
CFI
complement factor I
chr17_+_42429493 1.42 ENST00000586242.1
GRN
granulin
chr1_+_203595689 1.41 ENST00000357681.5
ATP2B4
ATPase, Ca++ transporting, plasma membrane 4
chr1_+_107599267 1.40 ENST00000361318.5
ENST00000370078.1
PRMT6
protein arginine methyltransferase 6
chr4_-_110723194 1.37 ENST00000394635.3
CFI
complement factor I
chr22_+_46449674 1.34 ENST00000381051.2
FLJ27365
hsa-mir-4763
chr1_-_32169920 1.32 ENST00000373672.3
ENST00000373668.3
COL16A1
collagen, type XVI, alpha 1
chr17_+_7461580 1.30 ENST00000483039.1
ENST00000396542.1
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr5_-_73937244 1.29 ENST00000302351.4
ENST00000510316.1
ENST00000508331.1
ENC1
ectodermal-neural cortex 1 (with BTB domain)
chr3_+_14058794 1.26 ENST00000424053.1
ENST00000528067.1
ENST00000429201.1
TPRXL
tetra-peptide repeat homeobox-like
chr7_+_18330035 1.24 ENST00000413509.2
HDAC9
histone deacetylase 9
chr6_-_28321909 1.23 ENST00000446222.1
ZSCAN31
zinc finger and SCAN domain containing 31
chr5_+_167181917 1.23 ENST00000519204.1
TENM2
teneurin transmembrane protein 2
chr14_+_75746664 1.21 ENST00000557139.1
FOS
FBJ murine osteosarcoma viral oncogene homolog
chr1_-_39407450 1.16 ENST00000372990.1
RHBDL2
rhomboid, veinlet-like 2 (Drosophila)
chr17_+_7461781 1.14 ENST00000349228.4
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr17_+_7461849 1.14 ENST00000338784.4
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr11_-_111784005 1.13 ENST00000527899.1
CRYAB
crystallin, alpha B
chr12_-_56122124 1.13 ENST00000552754.1
CD63
CD63 molecule
chr12_+_57522258 1.13 ENST00000553277.1
ENST00000243077.3
LRP1
low density lipoprotein receptor-related protein 1
chr11_-_57089671 1.12 ENST00000532437.1
TNKS1BP1
tankyrase 1 binding protein 1, 182kDa
chr1_-_39407467 1.11 ENST00000540558.1
RHBDL2
rhomboid, veinlet-like 2 (Drosophila)
chr17_+_7462031 1.11 ENST00000380535.4
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr1_-_32169761 1.11 ENST00000271069.6
COL16A1
collagen, type XVI, alpha 1
chr5_-_160365601 1.09 ENST00000518580.1
ENST00000518301.1
RP11-109J4.1
RP11-109J4.1
chr5_-_111092873 1.07 ENST00000509025.1
ENST00000515855.1
NREP
neuronal regeneration related protein
chr17_+_48503519 1.05 ENST00000300441.4
ENST00000541920.1
ENST00000506582.1
ENST00000504392.1
ENST00000427954.2
ACSF2
acyl-CoA synthetase family member 2
chr5_+_167182003 1.04 ENST00000520394.1
TENM2
teneurin transmembrane protein 2
chr19_+_3708376 1.04 ENST00000539908.2
TJP3
tight junction protein 3
chr2_-_219151487 1.03 ENST00000444881.1
TMBIM1
transmembrane BAX inhibitor motif containing 1
chr10_+_106034884 1.03 ENST00000369707.2
ENST00000429569.2
GSTO2
glutathione S-transferase omega 2
chr6_-_28321827 1.02 ENST00000444081.1
ZSCAN31
zinc finger and SCAN domain containing 31
chr1_+_113217345 1.01 ENST00000357443.2
MOV10
Mov10, Moloney leukemia virus 10, homolog (mouse)
chr12_+_6644443 0.99 ENST00000396858.1
GAPDH
glyceraldehyde-3-phosphate dehydrogenase
chr20_-_50722183 0.99 ENST00000371523.4
ZFP64
ZFP64 zinc finger protein
chr17_+_48503603 0.98 ENST00000502667.1
ACSF2
acyl-CoA synthetase family member 2
chr17_-_26903900 0.98 ENST00000395319.3
ENST00000581807.1
ENST00000584086.1
ENST00000395321.2
ALDOC
aldolase C, fructose-bisphosphate
chr5_-_115872124 0.97 ENST00000515009.1
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr8_-_42065075 0.96 ENST00000429089.2
ENST00000519510.1
ENST00000429710.2
ENST00000524009.1
PLAT
plasminogen activator, tissue
chr2_+_220325977 0.96 ENST00000396686.1
ENST00000396689.2
SPEG
SPEG complex locus
chr5_-_115872142 0.95 ENST00000510263.1
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr17_+_38334242 0.94 ENST00000436615.3
RAPGEFL1
Rap guanine nucleotide exchange factor (GEF)-like 1
chr9_-_23821842 0.92 ENST00000544538.1
ELAVL2
ELAV like neuron-specific RNA binding protein 2
chr20_+_58251716 0.92 ENST00000355648.4
PHACTR3
phosphatase and actin regulator 3
chr8_+_22022653 0.90 ENST00000354870.5
ENST00000397816.3
ENST00000306349.8
BMP1
bone morphogenetic protein 1
chr5_+_150020214 0.90 ENST00000307662.4
SYNPO
synaptopodin
chr14_-_65569244 0.89 ENST00000557277.1
ENST00000556892.1
MAX
MYC associated factor X
chr17_+_7462103 0.88 ENST00000396545.4
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr19_-_11450249 0.88 ENST00000222120.3
RAB3D
RAB3D, member RAS oncogene family
chr12_-_109797249 0.88 ENST00000538041.1
RP11-256L11.1
RP11-256L11.1
chr1_+_203595903 0.86 ENST00000367218.3
ENST00000367219.3
ENST00000391954.2
ATP2B4
ATPase, Ca++ transporting, plasma membrane 4
chr19_-_6737576 0.86 ENST00000601716.1
ENST00000264080.7
GPR108
G protein-coupled receptor 108
chr12_-_56122220 0.86 ENST00000552692.1
CD63
CD63 molecule
chr11_-_64764435 0.86 ENST00000534177.1
ENST00000301887.4
BATF2
basic leucine zipper transcription factor, ATF-like 2
chr17_-_74533734 0.84 ENST00000589342.1
CYGB
cytoglobin
chr3_+_46742823 0.83 ENST00000326431.3
TMIE
transmembrane inner ear
chr7_-_5463175 0.81 ENST00000399537.4
ENST00000430969.1
TNRC18
trinucleotide repeat containing 18
chr1_+_39456895 0.81 ENST00000432648.3
ENST00000446189.2
ENST00000372984.4
AKIRIN1
akirin 1
chr7_+_73242069 0.81 ENST00000435050.1
CLDN4
claudin 4
chr1_+_202995611 0.79 ENST00000367240.2
PPFIA4
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
chr1_+_113217043 0.79 ENST00000413052.2
MOV10
Mov10, Moloney leukemia virus 10, homolog (mouse)
chr21_+_39668831 0.79 ENST00000419868.1
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr8_-_42065187 0.79 ENST00000270189.6
ENST00000352041.3
ENST00000220809.4
PLAT
plasminogen activator, tissue
chr6_-_43595039 0.78 ENST00000307114.7
GTPBP2
GTP binding protein 2
chr9_+_124030338 0.77 ENST00000449773.1
ENST00000432226.1
ENST00000436847.1
ENST00000394353.2
ENST00000449733.1
ENST00000412819.1
ENST00000341272.2
ENST00000373808.2
GSN
gelsolin
chr19_+_4007644 0.76 ENST00000262971.2
PIAS4
protein inhibitor of activated STAT, 4
chr7_+_73242490 0.75 ENST00000431918.1
CLDN4
claudin 4
chr8_-_94752946 0.75 ENST00000519109.1
RBM12B
RNA binding motif protein 12B
chr13_+_111767650 0.72 ENST00000449979.1
ENST00000370623.3
ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chr19_-_10628117 0.72 ENST00000333430.4
S1PR5
sphingosine-1-phosphate receptor 5
chr14_+_73704201 0.71 ENST00000340738.5
ENST00000427855.1
ENST00000381166.3
PAPLN
papilin, proteoglycan-like sulfated glycoprotein
chr3_+_136649311 0.71 ENST00000469404.1
ENST00000467911.1
NCK1
NCK adaptor protein 1
chr11_+_18417813 0.71 ENST00000540430.1
ENST00000379412.5
LDHA
lactate dehydrogenase A
chr6_-_111927062 0.70 ENST00000359831.4
TRAF3IP2
TRAF3 interacting protein 2
chr3_-_50340996 0.70 ENST00000266031.4
ENST00000395143.2
ENST00000457214.2
ENST00000447605.2
ENST00000418723.1
ENST00000395144.2
HYAL1
hyaluronoglucosaminidase 1
chr2_+_66662510 0.70 ENST00000272369.9
ENST00000407092.2
MEIS1
Meis homeobox 1
chr8_-_144923112 0.70 ENST00000442628.2
NRBP2
nuclear receptor binding protein 2
chr1_+_113217073 0.70 ENST00000369645.1
MOV10
Mov10, Moloney leukemia virus 10, homolog (mouse)
chr19_+_16222439 0.69 ENST00000300935.3
RAB8A
RAB8A, member RAS oncogene family
chr6_-_138866823 0.68 ENST00000342260.5
NHSL1
NHS-like 1
chr5_-_176923846 0.68 ENST00000506537.1
PDLIM7
PDZ and LIM domain 7 (enigma)
chr4_+_144303093 0.68 ENST00000505913.1
GAB1
GRB2-associated binding protein 1
chr2_+_69001913 0.68 ENST00000409030.3
ENST00000409220.1
ARHGAP25
Rho GTPase activating protein 25
chr2_+_220325441 0.67 ENST00000396688.1
SPEG
SPEG complex locus
chr16_-_51185149 0.67 ENST00000566102.1
ENST00000541611.1
SALL1
spalt-like transcription factor 1
chr16_+_30662184 0.66 ENST00000300835.4
PRR14
proline rich 14
chr11_+_18417948 0.65 ENST00000542179.1
LDHA
lactate dehydrogenase A
chr7_-_100076873 0.64 ENST00000300181.2
TSC22D4
TSC22 domain family, member 4
chr9_-_130487143 0.63 ENST00000419060.1
PTRH1
peptidyl-tRNA hydrolase 1 homolog (S. cerevisiae)
chr16_+_30662050 0.63 ENST00000568754.1
PRR14
proline rich 14
chr13_-_41240717 0.63 ENST00000379561.5
FOXO1
forkhead box O1
chr11_+_18720316 0.62 ENST00000280734.2
TMEM86A
transmembrane protein 86A
chr17_+_48611853 0.62 ENST00000507709.1
ENST00000515126.1
ENST00000507467.1
EPN3
epsin 3
chr4_+_154387480 0.62 ENST00000409663.3
ENST00000440693.1
ENST00000409959.3
KIAA0922
KIAA0922
chr17_+_7461613 0.61 ENST00000438470.1
ENST00000436057.1
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr1_+_160370344 0.60 ENST00000368061.2
VANGL2
VANGL planar cell polarity protein 2
chr8_+_24772455 0.60 ENST00000433454.2
NEFM
neurofilament, medium polypeptide
chr8_+_22022800 0.59 ENST00000397814.3
BMP1
bone morphogenetic protein 1
chr16_-_69385681 0.59 ENST00000288025.3
TMED6
transmembrane emp24 protein transport domain containing 6
chr12_-_56121612 0.58 ENST00000546939.1
CD63
CD63 molecule
chr15_+_89182156 0.58 ENST00000379224.5
ISG20
interferon stimulated exonuclease gene 20kDa
chr5_-_111093167 0.58 ENST00000446294.2
ENST00000419114.2
NREP
neuronal regeneration related protein
chr1_+_153747746 0.58 ENST00000368661.3
SLC27A3
solute carrier family 27 (fatty acid transporter), member 3
chr16_+_57662138 0.58 ENST00000562414.1
ENST00000561969.1
ENST00000562631.1
ENST00000563445.1
ENST00000565338.1
ENST00000567702.1
GPR56
G protein-coupled receptor 56
chr1_+_113217309 0.56 ENST00000544796.1
ENST00000369644.1
MOV10
Mov10, Moloney leukemia virus 10, homolog (mouse)
chr20_-_44519839 0.56 ENST00000372518.4
NEURL2
neuralized E3 ubiquitin protein ligase 2
chr8_+_61822605 0.56 ENST00000526936.1
AC022182.1
AC022182.1
chr5_-_111093081 0.56 ENST00000453526.2
ENST00000509427.1
NREP
neuronal regeneration related protein
chr1_+_33231221 0.55 ENST00000294521.3
KIAA1522
KIAA1522
chr11_-_111781454 0.55 ENST00000533280.1
CRYAB
crystallin, alpha B
chr1_+_155146318 0.54 ENST00000368385.4
ENST00000545012.1
ENST00000392451.2
ENST00000368383.3
ENST00000368382.1
ENST00000334634.4
TRIM46
tripartite motif containing 46
chr7_-_100065686 0.54 ENST00000423266.1
ENST00000456330.1
TSC22D4
TSC22 domain family, member 4
chr22_-_37213045 0.54 ENST00000406910.2
ENST00000417718.2
PVALB
parvalbumin
chr1_+_95975672 0.54 ENST00000440116.2
ENST00000456933.1
RP11-286B14.1
RP11-286B14.1
chr15_+_89182178 0.54 ENST00000559876.1
ISG20
interferon stimulated exonuclease gene 20kDa
chr1_-_32264356 0.54 ENST00000452755.2
SPOCD1
SPOC domain containing 1
chr8_-_57233103 0.54 ENST00000303749.3
ENST00000522671.1
SDR16C5
short chain dehydrogenase/reductase family 16C, member 5
chr17_-_45899126 0.53 ENST00000007414.3
ENST00000392507.3
OSBPL7
oxysterol binding protein-like 7
chr1_+_33219592 0.53 ENST00000373481.3
KIAA1522
KIAA1522
chr5_+_72251793 0.53 ENST00000430046.2
ENST00000341845.6
FCHO2
FCH domain only 2
chr12_+_66218212 0.52 ENST00000393578.3
ENST00000425208.2
ENST00000536545.1
ENST00000354636.3
HMGA2
high mobility group AT-hook 2
chr10_+_106034637 0.52 ENST00000401888.2
GSTO2
glutathione S-transferase omega 2
chr1_+_1846519 0.52 ENST00000378604.3
CALML6
calmodulin-like 6
chr13_-_28194541 0.52 ENST00000316334.3
LNX2
ligand of numb-protein X 2
chr9_-_35618364 0.51 ENST00000378431.1
ENST00000378430.3
ENST00000259633.4
CD72
CD72 molecule
chr2_+_66662690 0.51 ENST00000488550.1
MEIS1
Meis homeobox 1
chr12_+_100867733 0.51 ENST00000546380.1
NR1H4
nuclear receptor subfamily 1, group H, member 4
chr10_+_129785536 0.51 ENST00000419012.2
PTPRE
protein tyrosine phosphatase, receptor type, E
chr15_+_89181974 0.51 ENST00000306072.5
ISG20
interferon stimulated exonuclease gene 20kDa
chr1_+_61547405 0.50 ENST00000371189.4
NFIA
nuclear factor I/A
chr4_+_86749045 0.50 ENST00000514229.1
ARHGAP24
Rho GTPase activating protein 24
chr20_+_48884002 0.50 ENST00000425497.1
ENST00000445003.1
RP11-290F20.3
RP11-290F20.3
chrX_+_46937745 0.50 ENST00000397180.1
ENST00000457380.1
ENST00000352078.4
RGN
regucalcin
chr16_+_57662419 0.49 ENST00000388812.4
ENST00000538815.1
ENST00000456916.1
ENST00000567154.1
ENST00000388813.5
ENST00000562558.1
ENST00000566271.2
GPR56
G protein-coupled receptor 56
chr10_+_88718314 0.49 ENST00000348795.4
SNCG
synuclein, gamma (breast cancer-specific protein 1)
chr1_+_200993071 0.49 ENST00000446333.1
ENST00000458003.1
RP11-168O16.1
RP11-168O16.1
chr4_-_140544386 0.49 ENST00000561977.1
RP11-308D13.3
RP11-308D13.3
chr16_+_57653596 0.48 ENST00000568791.1
ENST00000570044.1
GPR56
G protein-coupled receptor 56
chr3_+_48264816 0.47 ENST00000296435.2
ENST00000576243.1
CAMP
cathelicidin antimicrobial peptide
chr1_+_32674675 0.47 ENST00000409358.1
DCDC2B
doublecortin domain containing 2B
chr12_+_66217911 0.46 ENST00000403681.2
HMGA2
high mobility group AT-hook 2
chr22_+_50639408 0.46 ENST00000380903.2
SELO
Selenoprotein O
chr8_-_13134246 0.46 ENST00000503161.2
DLC1
deleted in liver cancer 1
chr2_-_219151984 0.46 ENST00000444000.1
ENST00000418569.1
TMBIM1
transmembrane BAX inhibitor motif containing 1
chr1_+_185703513 0.45 ENST00000271588.4
ENST00000367492.2
HMCN1
hemicentin 1

Network of associatons between targets according to the STRING database.

First level regulatory network of TLX1_NFIC

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.4 GO:0001300 chronological cell aging(GO:0001300)
1.1 3.3 GO:0046521 sphingoid catabolic process(GO:0046521)
0.9 6.6 GO:0071461 cellular response to redox state(GO:0071461)
0.9 3.7 GO:1990637 response to prolactin(GO:1990637)
0.9 5.4 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.8 2.3 GO:0033241 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.6 5.5 GO:0001661 conditioned taste aversion(GO:0001661)
0.5 6.2 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.5 1.0 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.5 1.4 GO:2000824 negative regulation of androgen receptor activity(GO:2000824)
0.5 3.3 GO:2000490 negative regulation of hepatic stellate cell activation(GO:2000490)
0.5 1.4 GO:0034970 histone H3-R2 methylation(GO:0034970)
0.5 10.8 GO:0090026 positive regulation of monocyte chemotaxis(GO:0090026)
0.4 6.6 GO:0032119 sequestering of zinc ion(GO:0032119)
0.4 1.5 GO:2000820 negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820)
0.4 5.8 GO:0015074 DNA integration(GO:0015074)
0.3 1.6 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.3 2.5 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.3 0.9 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.3 1.4 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.3 3.1 GO:0098795 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.3 1.6 GO:1902045 negative regulation of Fas signaling pathway(GO:1902045)
0.2 1.0 GO:0035978 mesodermal-endodermal cell signaling(GO:0003131) programmed DNA elimination(GO:0031049) chromosome breakage(GO:0031052) histone H2A-S139 phosphorylation(GO:0035978) positive regulation of cellular response to X-ray(GO:2000685)
0.2 0.7 GO:1903674 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.2 2.9 GO:0035826 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.2 4.5 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.2 1.5 GO:1902174 positive regulation of keratinocyte apoptotic process(GO:1902174)
0.2 0.4 GO:0042704 uterine wall breakdown(GO:0042704)
0.2 0.4 GO:0034165 positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
0.2 0.6 GO:0060488 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.2 0.6 GO:0033693 neurofilament bundle assembly(GO:0033693)
0.2 0.8 GO:0038185 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) histone H3-R17 methylation(GO:0034971) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.2 1.5 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.2 0.9 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.2 1.6 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.2 0.5 GO:1903625 negative regulation of DNA catabolic process(GO:1903625) regulation of aminoacyl-tRNA ligase activity(GO:1903630)
0.2 3.4 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.2 1.3 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.2 2.1 GO:1903672 positive regulation of sprouting angiogenesis(GO:1903672)
0.2 3.8 GO:0007021 tubulin complex assembly(GO:0007021)
0.1 5.4 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 0.9 GO:0098886 modification of dendritic spine(GO:0098886)
0.1 0.7 GO:0036118 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.1 1.0 GO:0072180 mesonephric duct morphogenesis(GO:0072180)
0.1 0.4 GO:0035284 rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.1 1.4 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.1 1.5 GO:0009407 toxin catabolic process(GO:0009407) secondary metabolite catabolic process(GO:0090487)
0.1 1.8 GO:0019317 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.1 0.3 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.1 0.3 GO:0001579 medium-chain fatty acid transport(GO:0001579)
0.1 0.6 GO:0035947 regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter(GO:0035947)
0.1 2.3 GO:0097264 self proteolysis(GO:0097264)
0.1 1.7 GO:0051451 myoblast migration(GO:0051451)
0.1 0.3 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.1 0.4 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.1 1.1 GO:0097475 motor neuron migration(GO:0097475)
0.1 0.3 GO:0050902 leukocyte adhesive activation(GO:0050902)
0.1 1.9 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.1 2.4 GO:0033622 integrin activation(GO:0033622)
0.1 0.4 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.1 0.1 GO:0098712 L-glutamate import across plasma membrane(GO:0098712)
0.1 0.6 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.1 0.4 GO:0015670 carbon dioxide transport(GO:0015670)
0.1 1.4 GO:0033160 positive regulation of protein import into nucleus, translocation(GO:0033160)
0.1 0.4 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.1 0.9 GO:0042940 D-amino acid transport(GO:0042940)
0.1 0.3 GO:0018894 dibenzo-p-dioxin metabolic process(GO:0018894)
0.1 1.5 GO:0060044 negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.1 0.4 GO:0061034 olfactory bulb mitral cell layer development(GO:0061034)
0.1 1.7 GO:0051639 actin filament network formation(GO:0051639)
0.1 0.2 GO:1904640 response to methionine(GO:1904640)
0.1 1.8 GO:0031639 plasminogen activation(GO:0031639)
0.1 0.2 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.1 1.7 GO:0048511 rhythmic process(GO:0048511)
0.1 1.0 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.1 1.4 GO:0032060 bleb assembly(GO:0032060)
0.1 1.3 GO:0006089 lactate metabolic process(GO:0006089)
0.1 1.0 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.1 0.9 GO:0030321 transepithelial chloride transport(GO:0030321)
0.1 0.4 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.1 0.5 GO:0051873 disruption by host of symbiont cells(GO:0051852) killing by host of symbiont cells(GO:0051873)
0.1 0.4 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.1 0.3 GO:0061107 seminal vesicle development(GO:0061107)
0.1 0.1 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
0.1 0.2 GO:0060018 astrocyte fate commitment(GO:0060018)
0.1 0.5 GO:0060745 mammary gland branching involved in pregnancy(GO:0060745)
0.1 0.9 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 1.5 GO:0001502 cartilage condensation(GO:0001502)
0.0 0.1 GO:0006258 UDP-glucose catabolic process(GO:0006258)
0.0 0.2 GO:0046086 adenosine biosynthetic process(GO:0046086)
0.0 0.2 GO:0099640 axo-dendritic protein transport(GO:0099640)
0.0 0.2 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.0 0.2 GO:0036079 GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
0.0 1.6 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.3 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.0 0.4 GO:0048875 chemical homeostasis within a tissue(GO:0048875)
0.0 0.5 GO:0099612 protein localization to axon(GO:0099612)
0.0 0.1 GO:1990922 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.0 0.6 GO:0015705 iodide transport(GO:0015705)
0.0 3.0 GO:0051693 actin filament capping(GO:0051693)
0.0 0.1 GO:0009624 response to nematode(GO:0009624)
0.0 0.1 GO:0018874 benzoate metabolic process(GO:0018874)
0.0 0.7 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.0 0.2 GO:0043686 co-translational protein modification(GO:0043686)
0.0 0.2 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 0.6 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 9.6 GO:0043542 endothelial cell migration(GO:0043542)
0.0 0.9 GO:0010800 positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0 0.2 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0 0.5 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.0 5.7 GO:0030038 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.0 0.1 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.0 0.3 GO:0023035 CD40 signaling pathway(GO:0023035)
0.0 1.9 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.5 GO:0042574 retinal metabolic process(GO:0042574)
0.0 0.9 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.0 0.7 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.0 0.5 GO:0072189 ureter development(GO:0072189)
0.0 0.2 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.3 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 0.2 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.1 GO:0048241 epinephrine transport(GO:0048241)
0.0 0.4 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.0 0.1 GO:0006522 alanine metabolic process(GO:0006522) alanine catabolic process(GO:0006524) pyruvate family amino acid metabolic process(GO:0009078) pyruvate family amino acid catabolic process(GO:0009080) D-amino acid metabolic process(GO:0046416)
0.0 0.3 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.0 0.6 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.2 GO:0048747 muscle fiber development(GO:0048747)
0.0 0.3 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.4 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.1 GO:0021847 ventricular zone neuroblast division(GO:0021847)
0.0 0.4 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.3 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.3 GO:0048368 lateral mesoderm development(GO:0048368)
0.0 0.2 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.4 GO:0008228 opsonization(GO:0008228)
0.0 0.3 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.2 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.1 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.0 0.1 GO:0044376 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.0 0.8 GO:0050673 epithelial cell proliferation(GO:0050673)
0.0 0.1 GO:0061622 glycolytic process through glucose-1-phosphate(GO:0061622) glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.0 0.8 GO:0010107 potassium ion import(GO:0010107)
0.0 0.3 GO:0050680 negative regulation of epithelial cell proliferation(GO:0050680)
0.0 1.0 GO:0007605 sensory perception of sound(GO:0007605) sensory perception of mechanical stimulus(GO:0050954)
0.0 0.8 GO:0014047 glutamate secretion(GO:0014047)
0.0 0.4 GO:0043401 steroid hormone mediated signaling pathway(GO:0043401)
0.0 0.2 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.0 0.2 GO:0071285 cellular response to lithium ion(GO:0071285)
0.0 0.2 GO:0070234 positive regulation of T cell apoptotic process(GO:0070234)
0.0 0.5 GO:0014887 muscle hypertrophy in response to stress(GO:0003299) cardiac muscle adaptation(GO:0014887) cardiac muscle hypertrophy in response to stress(GO:0014898)
0.0 0.1 GO:2001054 negative regulation of mesenchymal cell apoptotic process(GO:2001054)
0.0 0.3 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.1 GO:0048539 bone marrow development(GO:0048539)
0.0 0.5 GO:0014059 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 0.0 GO:0046271 phenylpropanoid catabolic process(GO:0046271)
0.0 0.2 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.4 GO:0072563 endothelial microparticle(GO:0072563)
0.7 3.4 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.6 5.5 GO:0035976 AP1 complex(GO:0035976)
0.5 2.1 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.4 4.5 GO:0005610 laminin-5 complex(GO:0005610)
0.3 0.9 GO:0097444 spine apparatus(GO:0097444)
0.2 0.7 GO:0036117 hyaluranon cable(GO:0036117)
0.2 2.9 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.2 3.8 GO:0097512 cardiac myofibril(GO:0097512)
0.2 1.4 GO:0032444 activin responsive factor complex(GO:0032444)
0.2 2.4 GO:0005593 FACIT collagen trimer(GO:0005593)
0.2 0.6 GO:0060187 cell pole(GO:0060187)
0.1 1.0 GO:0097452 GAIT complex(GO:0097452)
0.1 0.4 GO:0042025 host cell nucleus(GO:0042025)
0.1 0.5 GO:1990769 proximal neuron projection(GO:1990769)
0.1 0.8 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.1 0.8 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.1 0.9 GO:0000322 storage vacuole(GO:0000322)
0.1 0.3 GO:0036029 protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183)
0.1 0.3 GO:0036156 inner dynein arm(GO:0036156)
0.1 0.4 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.1 0.3 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.1 0.8 GO:0005677 chromatin silencing complex(GO:0005677)
0.1 1.9 GO:0031528 microvillus membrane(GO:0031528)
0.1 2.4 GO:0097228 sperm principal piece(GO:0097228)
0.1 0.8 GO:0030478 actin cap(GO:0030478)
0.0 0.6 GO:0005883 neurofilament(GO:0005883)
0.0 0.5 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.6 GO:0032426 stereocilium tip(GO:0032426)
0.0 7.3 GO:0016605 PML body(GO:0016605)
0.0 0.7 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 6.7 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 1.2 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.6 GO:0031209 SCAR complex(GO:0031209)
0.0 0.2 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.7 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 0.4 GO:0097433 dense body(GO:0097433)
0.0 1.3 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.4 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.3 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.9 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.4 GO:0042588 zymogen granule(GO:0042588)
0.0 0.3 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.3 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.5 GO:0043194 axon initial segment(GO:0043194)
0.0 0.9 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 2.7 GO:0005604 basement membrane(GO:0005604)
0.0 0.4 GO:0010369 chromocenter(GO:0010369)
0.0 0.8 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.2 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.2 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.2 GO:0000124 SAGA complex(GO:0000124)
0.0 0.4 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.3 GO:0035580 specific granule lumen(GO:0035580)
0.0 0.3 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 1.8 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.6 GO:0030673 axolemma(GO:0030673)
0.0 0.3 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 1.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.3 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.0 0.4 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.0 1.4 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.2 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 2.0 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 1.2 GO:0035097 histone methyltransferase complex(GO:0035097)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 6.8 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.8 3.3 GO:0047888 fatty acid peroxidase activity(GO:0047888)
0.8 2.5 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.8 2.3 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.6 6.6 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.5 1.6 GO:0008859 exoribonuclease II activity(GO:0008859)
0.5 1.4 GO:0016964 alpha-2 macroglobulin receptor activity(GO:0016964)
0.5 3.3 GO:0008481 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.4 3.4 GO:0005534 galactose binding(GO:0005534)
0.4 1.5 GO:0035939 microsatellite binding(GO:0035939)
0.4 1.4 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.3 3.4 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.3 1.5 GO:0050610 oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
0.2 1.0 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.2 1.0 GO:0035501 MH1 domain binding(GO:0035501)
0.2 1.0 GO:0060422 peptidyl-dipeptidase inhibitor activity(GO:0060422)
0.2 5.4 GO:0045499 chemorepellent activity(GO:0045499)
0.2 0.8 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.2 10.8 GO:0042379 chemokine receptor binding(GO:0042379)
0.2 2.0 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.2 2.1 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.2 0.6 GO:1990175 EH domain binding(GO:1990175)
0.1 0.7 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.1 0.7 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 1.4 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.1 6.8 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 0.6 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.1 1.9 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 0.4 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 1.1 GO:0071532 ankyrin repeat binding(GO:0071532)
0.1 7.0 GO:0070412 R-SMAD binding(GO:0070412)
0.1 1.8 GO:0008417 fucosyltransferase activity(GO:0008417)
0.1 0.3 GO:0043849 Ras palmitoyltransferase activity(GO:0043849)
0.1 0.8 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 0.5 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.1 1.0 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 0.4 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.1 1.9 GO:0017049 GTP-Rho binding(GO:0017049)
0.1 1.5 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.1 0.8 GO:0045159 myosin II binding(GO:0045159)
0.1 0.5 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.1 0.2 GO:0004613 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.1 0.6 GO:0001849 complement component C1q binding(GO:0001849)
0.1 0.6 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 0.4 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.1 1.8 GO:0031489 myosin V binding(GO:0031489)
0.0 0.2 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.0 0.2 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.0 1.6 GO:0005123 death receptor binding(GO:0005123)
0.0 0.2 GO:0036080 GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
0.0 0.5 GO:0036122 BMP binding(GO:0036122)
0.0 0.9 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.3 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.3 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.2 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.0 3.5 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.8 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 1.2 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.1 GO:0005277 acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375)
0.0 1.3 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 0.3 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 0.2 GO:0030345 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0 0.9 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 4.8 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 1.4 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.2 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.3 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.2 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.0 0.3 GO:0032190 acrosin binding(GO:0032190)
0.0 0.9 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.3 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.1 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
0.0 0.4 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.1 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.1 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.0 2.0 GO:0030551 cyclic nucleotide binding(GO:0030551)
0.0 0.8 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.5 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.1 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.4 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.3 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 9.0 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 1.8 GO:0001071 nucleic acid binding transcription factor activity(GO:0001071)
0.0 0.4 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 0.1 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.0 1.4 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 2.7 GO:0051082 unfolded protein binding(GO:0051082)
0.0 3.0 GO:0008083 growth factor activity(GO:0008083)
0.0 0.3 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.4 GO:0001848 complement binding(GO:0001848)
0.0 0.1 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0 0.3 GO:0001055 RNA polymerase I activity(GO:0001054) RNA polymerase II activity(GO:0001055)
0.0 3.0 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.2 GO:0015250 water channel activity(GO:0015250)
0.0 0.4 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.8 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 0.2 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.4 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.3 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.3 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.1 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.2 3.4 ST STAT3 PATHWAY STAT3 Pathway
0.2 4.5 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 5.7 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 3.8 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.1 10.4 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 6.3 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 4.9 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 4.7 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.1 7.4 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.1 0.5 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 20.1 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 4.2 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 1.1 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 2.1 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 2.4 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 1.3 PID MYC PATHWAY C-MYC pathway
0.0 0.8 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.8 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.6 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 1.6 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 1.6 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.3 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 1.0 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 1.2 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.3 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.2 NABA COLLAGENS Genes encoding collagen proteins
0.0 1.4 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.4 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.5 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.2 3.4 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.2 5.2 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 1.9 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 3.4 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.1 3.3 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 1.5 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 1.3 REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION Genes involved in Cyclin E associated events during G1/S transition
0.0 4.2 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 1.2 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 1.4 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 6.5 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 1.4 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 1.1 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.7 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 2.1 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 2.4 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 2.7 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 4.7 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0 1.3 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 1.7 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.0 0.7 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 1.0 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.3 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 5.8 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 1.6 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.7 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.5 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.3 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.8 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.5 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 0.3 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.9 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.4 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.2 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 1.0 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters