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SARS-CoV-2 Analysis Results (GEO series: GSE147507)
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Results for TLX2
Z-value: 1.77
Motif logo
Transcription factors associated with TLX2
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
TLX2
|
ENSG00000115297.9 | T cell leukemia homeobox 2 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| TLX2 | hg19_v2_chr2_+_74741569_74741620 | -0.72 | 3.8e-04 | Click! |
Activity profile of TLX2 motif
Sorted Z-values of TLX2 motif
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr1_+_86889769 | 7.58 |
ENST00000370565.4
|
CLCA2
|
chloride channel accessory 2 |
| chr1_+_153330322 | 7.51 |
ENST00000368738.3
|
S100A9
|
S100 calcium binding protein A9 |
| chr1_+_152881014 | 6.75 |
ENST00000368764.3
ENST00000392667.2 |
IVL
|
involucrin |
| chr1_-_153363452 | 6.72 |
ENST00000368732.1
ENST00000368733.3 |
S100A8
|
S100 calcium binding protein A8 |
| chr12_-_50677255 | 6.34 |
ENST00000551691.1
ENST00000394943.3 ENST00000341247.4 |
LIMA1
|
LIM domain and actin binding 1 |
| chr11_+_117947782 | 6.13 |
ENST00000522307.1
ENST00000523251.1 ENST00000437212.3 ENST00000522824.1 ENST00000522151.1 |
TMPRSS4
|
transmembrane protease, serine 4 |
| chr1_-_17304771 | 6.06 |
ENST00000375534.3
|
MFAP2
|
microfibrillar-associated protein 2 |
| chr3_+_50192457 | 4.83 |
ENST00000414301.1
ENST00000450338.1 |
SEMA3F
|
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F |
| chr3_+_50192499 | 4.69 |
ENST00000413852.1
|
SEMA3F
|
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F |
| chr16_-_68269971 | 4.62 |
ENST00000565858.1
|
ESRP2
|
epithelial splicing regulatory protein 2 |
| chr3_+_50192537 | 4.62 |
ENST00000002829.3
|
SEMA3F
|
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F |
| chr10_-_47173994 | 4.45 |
ENST00000414655.2
ENST00000545298.1 ENST00000359178.4 ENST00000358140.4 ENST00000503031.1 |
ANXA8L1
LINC00842
|
annexin A8-like 1 long intergenic non-protein coding RNA 842 |
| chr2_+_17721920 | 4.35 |
ENST00000295156.4
|
VSNL1
|
visinin-like 1 |
| chr15_+_41136586 | 4.10 |
ENST00000431806.1
|
SPINT1
|
serine peptidase inhibitor, Kunitz type 1 |
| chr10_+_71075516 | 4.07 |
ENST00000436817.1
|
HK1
|
hexokinase 1 |
| chr15_+_41136734 | 4.01 |
ENST00000568580.1
|
SPINT1
|
serine peptidase inhibitor, Kunitz type 1 |
| chr8_+_86376081 | 3.92 |
ENST00000285379.5
|
CA2
|
carbonic anhydrase II |
| chr4_-_90758227 | 3.70 |
ENST00000506691.1
ENST00000394986.1 ENST00000506244.1 ENST00000394989.2 ENST00000394991.3 |
SNCA
|
synuclein, alpha (non A4 component of amyloid precursor) |
| chrX_+_56259316 | 3.52 |
ENST00000468660.1
|
KLF8
|
Kruppel-like factor 8 |
| chr12_-_33049690 | 3.50 |
ENST00000070846.6
ENST00000340811.4 |
PKP2
|
plakophilin 2 |
| chr1_-_161046266 | 3.46 |
ENST00000453926.2
|
PVRL4
|
poliovirus receptor-related 4 |
| chr8_+_120220561 | 3.45 |
ENST00000276681.6
|
MAL2
|
mal, T-cell differentiation protein 2 (gene/pseudogene) |
| chr18_+_29078131 | 3.44 |
ENST00000585206.1
|
DSG2
|
desmoglein 2 |
| chr10_+_48255253 | 3.42 |
ENST00000357718.4
ENST00000344416.5 ENST00000456111.2 ENST00000374258.3 |
ANXA8
AL591684.1
|
annexin A8 Protein LOC100996760 |
| chr10_+_47746929 | 3.32 |
ENST00000340243.6
ENST00000374277.5 ENST00000449464.2 ENST00000538825.1 ENST00000335083.5 |
ANXA8L2
AL603965.1
|
annexin A8-like 2 Protein LOC100996760 |
| chr5_+_68711023 | 3.29 |
ENST00000515844.1
|
MARVELD2
|
MARVEL domain containing 2 |
| chr17_+_66509019 | 3.22 |
ENST00000585981.1
ENST00000589480.1 ENST00000585815.1 |
PRKAR1A
|
protein kinase, cAMP-dependent, regulatory, type I, alpha |
| chr6_-_32634425 | 3.13 |
ENST00000399082.3
ENST00000399079.3 ENST00000374943.4 ENST00000434651.2 |
HLA-DQB1
|
major histocompatibility complex, class II, DQ beta 1 |
| chr14_-_24732738 | 3.08 |
ENST00000558074.1
ENST00000560226.1 |
TGM1
|
transglutaminase 1 |
| chr17_-_33760164 | 3.03 |
ENST00000445092.1
ENST00000394562.1 ENST00000447040.2 |
SLFN12
|
schlafen family member 12 |
| chr3_+_118892362 | 2.91 |
ENST00000497685.1
ENST00000264234.3 |
UPK1B
|
uroplakin 1B |
| chr3_+_118892411 | 2.91 |
ENST00000479520.1
ENST00000494855.1 |
UPK1B
|
uroplakin 1B |
| chr10_-_4720333 | 2.84 |
ENST00000430998.2
|
LINC00704
|
long intergenic non-protein coding RNA 704 |
| chr11_+_117947724 | 2.76 |
ENST00000534111.1
|
TMPRSS4
|
transmembrane protease, serine 4 |
| chr14_+_71788096 | 2.75 |
ENST00000557151.1
|
SIPA1L1
|
signal-induced proliferation-associated 1 like 1 |
| chr6_+_116692102 | 2.73 |
ENST00000359564.2
|
DSE
|
dermatan sulfate epimerase |
| chr19_-_51512804 | 2.71 |
ENST00000594211.1
ENST00000376832.4 |
KLK9
|
kallikrein-related peptidase 9 |
| chr2_+_192543694 | 2.62 |
ENST00000435931.1
|
NABP1
|
nucleic acid binding protein 1 |
| chr10_-_115933942 | 2.59 |
ENST00000369285.3
ENST00000369287.3 ENST00000369286.1 |
C10orf118
|
chromosome 10 open reading frame 118 |
| chr1_+_31769836 | 2.59 |
ENST00000344147.5
ENST00000373714.1 ENST00000546109.1 ENST00000422613.2 |
ZCCHC17
|
zinc finger, CCHC domain containing 17 |
| chr19_-_53636125 | 2.57 |
ENST00000601493.1
ENST00000599261.1 ENST00000597503.1 ENST00000500065.4 ENST00000243643.4 ENST00000594011.1 ENST00000455735.2 ENST00000595193.1 ENST00000448501.1 ENST00000421033.1 ENST00000440291.1 ENST00000595813.1 ENST00000600574.1 ENST00000596051.1 ENST00000601110.1 |
ZNF415
|
zinc finger protein 415 |
| chr2_+_192543153 | 2.55 |
ENST00000425611.2
|
NABP1
|
nucleic acid binding protein 1 |
| chr10_-_4720301 | 2.54 |
ENST00000449712.1
|
LINC00704
|
long intergenic non-protein coding RNA 704 |
| chr14_-_23762777 | 2.50 |
ENST00000431326.2
|
HOMEZ
|
homeobox and leucine zipper encoding |
| chr12_+_57522692 | 2.49 |
ENST00000554174.1
|
LRP1
|
low density lipoprotein receptor-related protein 1 |
| chr1_+_152486950 | 2.44 |
ENST00000368790.3
|
CRCT1
|
cysteine-rich C-terminal 1 |
| chr18_+_29077990 | 2.43 |
ENST00000261590.8
|
DSG2
|
desmoglein 2 |
| chr19_-_11688500 | 2.41 |
ENST00000433365.2
|
ACP5
|
acid phosphatase 5, tartrate resistant |
| chr7_+_90225796 | 2.40 |
ENST00000380050.3
|
CDK14
|
cyclin-dependent kinase 14 |
| chr2_-_224702201 | 2.38 |
ENST00000446015.2
|
AP1S3
|
adaptor-related protein complex 1, sigma 3 subunit |
| chr2_+_169923504 | 2.36 |
ENST00000357546.2
|
DHRS9
|
dehydrogenase/reductase (SDR family) member 9 |
| chr2_-_219146839 | 2.35 |
ENST00000425694.1
|
TMBIM1
|
transmembrane BAX inhibitor motif containing 1 |
| chr1_+_205473720 | 2.35 |
ENST00000429964.2
ENST00000506784.1 ENST00000360066.2 |
CDK18
|
cyclin-dependent kinase 18 |
| chr1_+_205473784 | 2.35 |
ENST00000478560.1
ENST00000443813.2 |
CDK18
|
cyclin-dependent kinase 18 |
| chr10_+_111765562 | 2.34 |
ENST00000360162.3
|
ADD3
|
adducin 3 (gamma) |
| chr8_+_123875624 | 2.31 |
ENST00000534247.1
|
ZHX2
|
zinc fingers and homeoboxes 2 |
| chr10_+_71075552 | 2.29 |
ENST00000298649.3
|
HK1
|
hexokinase 1 |
| chr1_-_22222764 | 2.23 |
ENST00000439717.2
ENST00000412328.1 |
HSPG2
|
heparan sulfate proteoglycan 2 |
| chr14_+_65170820 | 2.22 |
ENST00000555982.1
|
PLEKHG3
|
pleckstrin homology domain containing, family G (with RhoGef domain) member 3 |
| chr6_-_138428613 | 2.22 |
ENST00000421351.3
|
PERP
|
PERP, TP53 apoptosis effector |
| chr4_+_2814011 | 2.19 |
ENST00000502260.1
ENST00000435136.2 |
SH3BP2
|
SH3-domain binding protein 2 |
| chr1_-_32169920 | 2.19 |
ENST00000373672.3
ENST00000373668.3 |
COL16A1
|
collagen, type XVI, alpha 1 |
| chr4_+_169552748 | 2.17 |
ENST00000504519.1
ENST00000512127.1 |
PALLD
|
palladin, cytoskeletal associated protein |
| chr8_+_38758737 | 2.14 |
ENST00000521746.1
ENST00000420274.1 |
PLEKHA2
|
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 |
| chr19_+_50084561 | 2.14 |
ENST00000246794.5
|
PRRG2
|
proline rich Gla (G-carboxyglutamic acid) 2 |
| chr10_+_88718397 | 2.12 |
ENST00000372017.3
|
SNCG
|
synuclein, gamma (breast cancer-specific protein 1) |
| chr20_-_1472029 | 2.12 |
ENST00000359801.3
|
SIRPB2
|
signal-regulatory protein beta 2 |
| chr8_-_55014336 | 2.11 |
ENST00000343231.6
|
LYPLA1
|
lysophospholipase I |
| chr1_+_36789335 | 2.10 |
ENST00000373137.2
|
RP11-268J15.5
|
RP11-268J15.5 |
| chr5_+_68710906 | 2.10 |
ENST00000325631.5
ENST00000454295.2 |
MARVELD2
|
MARVEL domain containing 2 |
| chr17_-_80797886 | 2.09 |
ENST00000572562.1
|
ZNF750
|
zinc finger protein 750 |
| chr22_-_22221658 | 2.09 |
ENST00000544786.1
|
MAPK1
|
mitogen-activated protein kinase 1 |
| chr11_+_35160709 | 2.08 |
ENST00000415148.2
ENST00000433354.2 ENST00000449691.2 ENST00000437706.2 ENST00000360158.4 ENST00000428726.2 ENST00000526669.2 ENST00000433892.2 ENST00000278386.6 ENST00000434472.2 ENST00000352818.4 ENST00000442151.2 |
CD44
|
CD44 molecule (Indian blood group) |
| chr1_+_16083154 | 2.07 |
ENST00000375771.1
|
FBLIM1
|
filamin binding LIM protein 1 |
| chr20_-_1373682 | 2.07 |
ENST00000381724.3
|
FKBP1A
|
FK506 binding protein 1A, 12kDa |
| chr8_+_38758845 | 2.05 |
ENST00000519640.1
|
PLEKHA2
|
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 |
| chr2_+_102928009 | 2.03 |
ENST00000404917.2
ENST00000447231.1 |
IL1RL1
|
interleukin 1 receptor-like 1 |
| chr11_+_69924639 | 2.01 |
ENST00000538023.1
ENST00000398543.2 |
ANO1
|
anoctamin 1, calcium activated chloride channel |
| chr10_+_88718314 | 1.99 |
ENST00000348795.4
|
SNCG
|
synuclein, gamma (breast cancer-specific protein 1) |
| chr7_+_142982023 | 1.98 |
ENST00000359333.3
ENST00000409244.1 ENST00000409541.1 ENST00000410004.1 |
TMEM139
|
transmembrane protein 139 |
| chr6_+_37787704 | 1.96 |
ENST00000474522.1
|
ZFAND3
|
zinc finger, AN1-type domain 3 |
| chr1_-_68698197 | 1.95 |
ENST00000370973.2
ENST00000370971.1 |
WLS
|
wntless Wnt ligand secretion mediator |
| chr11_-_96076334 | 1.93 |
ENST00000524717.1
|
MAML2
|
mastermind-like 2 (Drosophila) |
| chr16_-_28192360 | 1.92 |
ENST00000570033.1
|
XPO6
|
exportin 6 |
| chr3_+_138067666 | 1.91 |
ENST00000475711.1
ENST00000464896.1 |
MRAS
|
muscle RAS oncogene homolog |
| chr3_-_122233723 | 1.91 |
ENST00000493510.1
ENST00000344337.6 ENST00000476916.1 ENST00000465882.1 |
KPNA1
|
karyopherin alpha 1 (importin alpha 5) |
| chr1_-_6526167 | 1.91 |
ENST00000351748.3
ENST00000348333.3 |
TNFRSF25
|
tumor necrosis factor receptor superfamily, member 25 |
| chr1_+_24646002 | 1.90 |
ENST00000356046.2
|
GRHL3
|
grainyhead-like 3 (Drosophila) |
| chr11_-_65429891 | 1.89 |
ENST00000527874.1
|
RELA
|
v-rel avian reticuloendotheliosis viral oncogene homolog A |
| chr1_-_6526192 | 1.88 |
ENST00000377782.3
ENST00000351959.5 ENST00000356876.3 |
TNFRSF25
|
tumor necrosis factor receptor superfamily, member 25 |
| chr2_+_169923577 | 1.88 |
ENST00000432060.2
|
DHRS9
|
dehydrogenase/reductase (SDR family) member 9 |
| chr3_+_121774202 | 1.87 |
ENST00000469710.1
ENST00000493101.1 ENST00000330540.2 ENST00000264468.5 |
CD86
|
CD86 molecule |
| chr12_+_57522439 | 1.85 |
ENST00000338962.4
|
LRP1
|
low density lipoprotein receptor-related protein 1 |
| chr19_+_37096194 | 1.85 |
ENST00000460670.1
ENST00000292928.2 ENST00000439428.1 |
ZNF382
|
zinc finger protein 382 |
| chr1_-_183538319 | 1.85 |
ENST00000420553.1
ENST00000419402.1 |
NCF2
|
neutrophil cytosolic factor 2 |
| chr1_+_24645865 | 1.84 |
ENST00000342072.4
|
GRHL3
|
grainyhead-like 3 (Drosophila) |
| chr4_+_2813946 | 1.83 |
ENST00000442312.2
|
SH3BP2
|
SH3-domain binding protein 2 |
| chr2_+_17721937 | 1.83 |
ENST00000451533.1
|
VSNL1
|
visinin-like 1 |
| chr17_-_33759509 | 1.82 |
ENST00000304905.5
|
SLFN12
|
schlafen family member 12 |
| chr3_-_105587879 | 1.82 |
ENST00000264122.4
ENST00000403724.1 ENST00000405772.1 |
CBLB
|
Cbl proto-oncogene B, E3 ubiquitin protein ligase |
| chr19_-_11688447 | 1.81 |
ENST00000590420.1
|
ACP5
|
acid phosphatase 5, tartrate resistant |
| chr3_-_195997410 | 1.80 |
ENST00000419333.1
|
PCYT1A
|
phosphate cytidylyltransferase 1, choline, alpha |
| chr11_-_123065989 | 1.79 |
ENST00000448775.2
|
CLMP
|
CXADR-like membrane protein |
| chr5_+_149877334 | 1.78 |
ENST00000523767.1
|
NDST1
|
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 |
| chr3_-_64253655 | 1.77 |
ENST00000498162.1
|
PRICKLE2
|
prickle homolog 2 (Drosophila) |
| chr19_+_58193388 | 1.76 |
ENST00000596085.1
ENST00000594684.1 |
ZNF551
AC003006.7
|
zinc finger protein 551 Uncharacterized protein |
| chr6_-_143266297 | 1.76 |
ENST00000367603.2
|
HIVEP2
|
human immunodeficiency virus type I enhancer binding protein 2 |
| chr8_-_55014018 | 1.76 |
ENST00000521352.1
|
LYPLA1
|
lysophospholipase I |
| chr5_+_40841410 | 1.75 |
ENST00000381677.3
|
CARD6
|
caspase recruitment domain family, member 6 |
| chr1_+_24645807 | 1.74 |
ENST00000361548.4
|
GRHL3
|
grainyhead-like 3 (Drosophila) |
| chr7_+_18330035 | 1.74 |
ENST00000413509.2
|
HDAC9
|
histone deacetylase 9 |
| chr4_-_90758118 | 1.74 |
ENST00000420646.2
|
SNCA
|
synuclein, alpha (non A4 component of amyloid precursor) |
| chr1_+_26872324 | 1.74 |
ENST00000531382.1
|
RPS6KA1
|
ribosomal protein S6 kinase, 90kDa, polypeptide 1 |
| chr2_+_102927962 | 1.74 |
ENST00000233954.1
ENST00000393393.3 ENST00000410040.1 |
IL1RL1
IL18R1
|
interleukin 1 receptor-like 1 interleukin 18 receptor 1 |
| chr1_+_43148625 | 1.73 |
ENST00000436427.1
|
YBX1
|
Y box binding protein 1 |
| chr17_-_33760269 | 1.72 |
ENST00000452764.3
|
SLFN12
|
schlafen family member 12 |
| chr4_-_36246060 | 1.71 |
ENST00000303965.4
|
ARAP2
|
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 |
| chr14_+_37131058 | 1.69 |
ENST00000361487.6
|
PAX9
|
paired box 9 |
| chr9_-_80645520 | 1.63 |
ENST00000411677.1
|
GNAQ
|
guanine nucleotide binding protein (G protein), q polypeptide |
| chr8_-_128231299 | 1.63 |
ENST00000500112.1
|
CCAT1
|
colon cancer associated transcript 1 (non-protein coding) |
| chr7_-_80548493 | 1.62 |
ENST00000536800.1
|
SEMA3C
|
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C |
| chr15_+_74218787 | 1.62 |
ENST00000261921.7
|
LOXL1
|
lysyl oxidase-like 1 |
| chr8_-_55014415 | 1.62 |
ENST00000522007.1
ENST00000521898.1 ENST00000518546.1 ENST00000316963.3 |
LYPLA1
|
lysophospholipase I |
| chr4_+_156680153 | 1.61 |
ENST00000502959.1
ENST00000505764.1 ENST00000507146.1 ENST00000264424.8 ENST00000503520.1 |
GUCY1B3
|
guanylate cyclase 1, soluble, beta 3 |
| chr1_-_31902614 | 1.60 |
ENST00000596131.1
|
AC114494.1
|
HCG1787699; Uncharacterized protein |
| chr14_-_21737610 | 1.60 |
ENST00000320084.7
ENST00000449098.1 ENST00000336053.6 |
HNRNPC
|
heterogeneous nuclear ribonucleoprotein C (C1/C2) |
| chr15_+_42694573 | 1.60 |
ENST00000397200.4
ENST00000569827.1 |
CAPN3
|
calpain 3, (p94) |
| chr20_+_56884752 | 1.59 |
ENST00000244040.3
|
RAB22A
|
RAB22A, member RAS oncogene family |
| chr1_+_24286287 | 1.58 |
ENST00000334351.7
ENST00000374468.1 |
PNRC2
|
proline-rich nuclear receptor coactivator 2 |
| chr5_+_110407390 | 1.58 |
ENST00000344895.3
|
TSLP
|
thymic stromal lymphopoietin |
| chr16_+_82068830 | 1.57 |
ENST00000199936.4
|
HSD17B2
|
hydroxysteroid (17-beta) dehydrogenase 2 |
| chr6_+_111303218 | 1.56 |
ENST00000441448.2
|
RPF2
|
ribosome production factor 2 homolog (S. cerevisiae) |
| chr11_+_62186498 | 1.56 |
ENST00000278282.2
|
SCGB1A1
|
secretoglobin, family 1A, member 1 (uteroglobin) |
| chr1_+_24645915 | 1.56 |
ENST00000350501.5
|
GRHL3
|
grainyhead-like 3 (Drosophila) |
| chr1_-_68698222 | 1.55 |
ENST00000370976.3
ENST00000354777.2 ENST00000262348.4 ENST00000540432.1 |
WLS
|
wntless Wnt ligand secretion mediator |
| chr4_+_71384257 | 1.54 |
ENST00000339336.4
|
AMTN
|
amelotin |
| chr19_-_12833361 | 1.54 |
ENST00000592287.1
|
TNPO2
|
transportin 2 |
| chr1_+_16174280 | 1.53 |
ENST00000375759.3
|
SPEN
|
spen family transcriptional repressor |
| chr4_+_71384300 | 1.51 |
ENST00000504451.1
|
AMTN
|
amelotin |
| chr14_-_67859422 | 1.51 |
ENST00000556532.1
|
PLEK2
|
pleckstrin 2 |
| chr14_-_21737551 | 1.51 |
ENST00000554891.1
ENST00000555883.1 ENST00000553753.1 ENST00000555914.1 ENST00000557336.1 ENST00000555215.1 ENST00000556628.1 ENST00000555137.1 ENST00000556226.1 ENST00000555309.1 ENST00000556142.1 ENST00000554969.1 ENST00000554455.1 ENST00000556513.1 ENST00000557201.1 ENST00000420743.2 ENST00000557768.1 ENST00000553300.1 ENST00000554383.1 ENST00000554539.1 |
HNRNPC
|
heterogeneous nuclear ribonucleoprotein C (C1/C2) |
| chr20_-_1472121 | 1.50 |
ENST00000444444.2
|
SIRPB2
|
signal-regulatory protein beta 2 |
| chr5_+_67576062 | 1.49 |
ENST00000523807.1
|
PIK3R1
|
phosphoinositide-3-kinase, regulatory subunit 1 (alpha) |
| chr11_+_57435441 | 1.48 |
ENST00000528177.1
|
ZDHHC5
|
zinc finger, DHHC-type containing 5 |
| chr16_+_15744078 | 1.48 |
ENST00000396354.1
ENST00000570727.1 |
NDE1
|
nudE neurodevelopment protein 1 |
| chr17_+_66508537 | 1.47 |
ENST00000392711.1
ENST00000585427.1 ENST00000589228.1 ENST00000536854.2 ENST00000588702.1 ENST00000589309.1 |
PRKAR1A
|
protein kinase, cAMP-dependent, regulatory, type I, alpha |
| chr9_+_128024067 | 1.46 |
ENST00000461379.1
ENST00000394084.1 ENST00000394105.2 ENST00000470056.1 ENST00000394104.2 ENST00000265956.4 ENST00000394083.2 ENST00000495955.1 ENST00000467750.1 ENST00000297933.6 |
GAPVD1
|
GTPase activating protein and VPS9 domains 1 |
| chr5_+_159656437 | 1.45 |
ENST00000402432.3
|
FABP6
|
fatty acid binding protein 6, ileal |
| chr18_+_55862622 | 1.44 |
ENST00000456173.2
|
NEDD4L
|
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase |
| chr12_+_101188718 | 1.43 |
ENST00000299222.9
ENST00000392977.3 |
ANO4
|
anoctamin 4 |
| chr1_+_95286151 | 1.42 |
ENST00000467909.1
ENST00000422520.2 ENST00000532427.1 |
SLC44A3
|
solute carrier family 44, member 3 |
| chr12_-_54785074 | 1.42 |
ENST00000338010.5
ENST00000550774.1 |
ZNF385A
|
zinc finger protein 385A |
| chr4_+_39046615 | 1.42 |
ENST00000261425.3
ENST00000508137.2 |
KLHL5
|
kelch-like family member 5 |
| chr11_-_33744256 | 1.42 |
ENST00000415002.2
ENST00000437761.2 ENST00000445143.2 |
CD59
|
CD59 molecule, complement regulatory protein |
| chr8_+_27183033 | 1.42 |
ENST00000420218.2
|
PTK2B
|
protein tyrosine kinase 2 beta |
| chr4_+_78078304 | 1.41 |
ENST00000316355.5
ENST00000354403.5 ENST00000502280.1 |
CCNG2
|
cyclin G2 |
| chr13_+_60971080 | 1.41 |
ENST00000377894.2
|
TDRD3
|
tudor domain containing 3 |
| chr19_+_47104553 | 1.41 |
ENST00000598871.1
ENST00000594523.1 |
CALM3
|
calmodulin 3 (phosphorylase kinase, delta) |
| chr12_+_64798826 | 1.37 |
ENST00000540203.1
|
XPOT
|
exportin, tRNA |
| chr3_-_105588231 | 1.36 |
ENST00000545639.1
ENST00000394027.3 ENST00000438603.1 ENST00000447441.1 ENST00000443752.1 |
CBLB
|
Cbl proto-oncogene B, E3 ubiquitin protein ligase |
| chr13_+_60971427 | 1.34 |
ENST00000535286.1
ENST00000377881.2 |
TDRD3
|
tudor domain containing 3 |
| chr2_-_224702270 | 1.33 |
ENST00000396654.2
ENST00000396653.2 ENST00000423110.1 ENST00000443700.1 |
AP1S3
|
adaptor-related protein complex 1, sigma 3 subunit |
| chr6_-_56819385 | 1.33 |
ENST00000370754.5
ENST00000449297.2 |
DST
|
dystonin |
| chr21_-_38639601 | 1.32 |
ENST00000539844.1
ENST00000476950.1 ENST00000399001.1 |
DSCR3
|
Down syndrome critical region gene 3 |
| chr1_-_32169761 | 1.31 |
ENST00000271069.6
|
COL16A1
|
collagen, type XVI, alpha 1 |
| chr12_+_32687221 | 1.31 |
ENST00000525053.1
|
FGD4
|
FYVE, RhoGEF and PH domain containing 4 |
| chr1_-_22263790 | 1.31 |
ENST00000374695.3
|
HSPG2
|
heparan sulfate proteoglycan 2 |
| chr5_+_133984462 | 1.31 |
ENST00000398844.2
ENST00000322887.4 |
SEC24A
|
SEC24 family member A |
| chr2_+_160568978 | 1.30 |
ENST00000409175.1
ENST00000539065.1 ENST00000259050.4 ENST00000421037.1 |
MARCH7
|
membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase |
| chr14_-_21270995 | 1.30 |
ENST00000555698.1
ENST00000397970.4 ENST00000340900.3 |
RNASE1
|
ribonuclease, RNase A family, 1 (pancreatic) |
| chr14_+_55034599 | 1.29 |
ENST00000392067.3
ENST00000357634.3 |
SAMD4A
|
sterile alpha motif domain containing 4A |
| chr1_-_26324534 | 1.28 |
ENST00000374284.1
ENST00000441420.1 ENST00000374282.3 |
PAFAH2
|
platelet-activating factor acetylhydrolase 2, 40kDa |
| chr8_-_91657740 | 1.28 |
ENST00000422900.1
|
TMEM64
|
transmembrane protein 64 |
| chr11_-_46639436 | 1.24 |
ENST00000532281.1
|
HARBI1
|
harbinger transposase derived 1 |
| chr3_+_138067521 | 1.23 |
ENST00000494949.1
|
MRAS
|
muscle RAS oncogene homolog |
| chr1_-_224033596 | 1.23 |
ENST00000391878.2
ENST00000343537.7 |
TP53BP2
|
tumor protein p53 binding protein, 2 |
| chr14_+_61789382 | 1.23 |
ENST00000555082.1
|
PRKCH
|
protein kinase C, eta |
| chr2_-_242255117 | 1.23 |
ENST00000420451.1
ENST00000417540.1 ENST00000310931.4 |
HDLBP
|
high density lipoprotein binding protein |
| chr19_-_4517613 | 1.23 |
ENST00000301286.3
|
PLIN4
|
perilipin 4 |
| chr21_-_38639813 | 1.23 |
ENST00000309117.6
ENST00000398998.1 |
DSCR3
|
Down syndrome critical region gene 3 |
| chr19_-_6767431 | 1.23 |
ENST00000437152.3
ENST00000597687.1 |
SH2D3A
|
SH2 domain containing 3A |
| chr4_-_147443043 | 1.23 |
ENST00000394059.4
ENST00000502607.1 ENST00000335472.7 ENST00000432059.2 ENST00000394062.3 |
SLC10A7
|
solute carrier family 10, member 7 |
| chr14_+_65171315 | 1.21 |
ENST00000394691.1
|
PLEKHG3
|
pleckstrin homology domain containing, family G (with RhoGef domain) member 3 |
| chr5_+_131409476 | 1.21 |
ENST00000296871.2
|
CSF2
|
colony stimulating factor 2 (granulocyte-macrophage) |
| chr3_-_133969673 | 1.21 |
ENST00000427044.2
|
RYK
|
receptor-like tyrosine kinase |
| chr19_-_37096139 | 1.21 |
ENST00000585983.1
ENST00000585960.1 ENST00000586115.1 |
ZNF529
|
zinc finger protein 529 |
| chr4_+_90032651 | 1.20 |
ENST00000603357.1
|
RP11-84C13.1
|
RP11-84C13.1 |
| chr22_+_19706958 | 1.20 |
ENST00000395109.2
|
SEPT5
|
septin 5 |
| chr14_+_65171099 | 1.20 |
ENST00000247226.7
|
PLEKHG3
|
pleckstrin homology domain containing, family G (with RhoGef domain) member 3 |
| chr3_-_133969437 | 1.19 |
ENST00000460933.1
ENST00000296084.4 |
RYK
|
receptor-like tyrosine kinase |
| chr6_-_52926539 | 1.19 |
ENST00000350082.5
ENST00000356971.3 |
ICK
|
intestinal cell (MAK-like) kinase |
| chr1_+_92764522 | 1.19 |
ENST00000610020.1
|
RPAP2
|
RNA polymerase II associated protein 2 |
| chr3_+_30647994 | 1.19 |
ENST00000295754.5
|
TGFBR2
|
transforming growth factor, beta receptor II (70/80kDa) |
| chr1_+_24018269 | 1.18 |
ENST00000374550.3
|
RPL11
|
ribosomal protein L11 |
| chr3_-_178789220 | 1.17 |
ENST00000414084.1
|
ZMAT3
|
zinc finger, matrin-type 3 |
| chr1_+_35734562 | 1.17 |
ENST00000314607.6
ENST00000373297.2 |
ZMYM4
|
zinc finger, MYM-type 4 |
| chr11_+_69924679 | 1.17 |
ENST00000531604.1
|
ANO1
|
anoctamin 1, calcium activated chloride channel |
| chr20_-_47894936 | 1.16 |
ENST00000371754.4
|
ZNFX1
|
zinc finger, NFX1-type containing 1 |
| chr19_+_1026566 | 1.14 |
ENST00000348419.3
ENST00000565096.2 ENST00000562958.2 ENST00000562075.2 ENST00000607102.1 |
CNN2
|
calponin 2 |
| chr1_+_62417957 | 1.14 |
ENST00000307297.7
ENST00000543708.1 |
INADL
|
InaD-like (Drosophila) |
Network of associatons between targets according to the STRING database.
First level regulatory network of TLX2
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.5 | 7.5 | GO:0035606 | peptidyl-cysteine S-trans-nitrosylation(GO:0035606) |
| 1.4 | 6.8 | GO:0018153 | isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262) |
| 1.3 | 3.9 | GO:0042938 | dipeptide transport(GO:0042938) |
| 1.2 | 5.9 | GO:0003165 | Purkinje myocyte development(GO:0003165) |
| 1.1 | 5.4 | GO:1903282 | negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470) |
| 1.0 | 3.1 | GO:0070175 | positive regulation of enamel mineralization(GO:0070175) |
| 1.0 | 2.9 | GO:0002644 | negative regulation of tolerance induction(GO:0002644) positive regulation of interleukin-4 biosynthetic process(GO:0045404) |
| 0.9 | 2.6 | GO:0019858 | cytosine metabolic process(GO:0019858) |
| 0.9 | 3.5 | GO:0061357 | positive regulation of Wnt protein secretion(GO:0061357) |
| 0.9 | 4.3 | GO:1905167 | positive regulation of lysosomal protein catabolic process(GO:1905167) |
| 0.9 | 12.2 | GO:0036484 | trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) neural crest cell migration involved in autonomic nervous system development(GO:1901166) |
| 0.9 | 3.4 | GO:1900138 | negative regulation of phospholipase A2 activity(GO:1900138) |
| 0.7 | 2.8 | GO:2000435 | regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435) |
| 0.7 | 3.5 | GO:0048496 | adherens junction maintenance(GO:0034334) maintenance of organ identity(GO:0048496) |
| 0.7 | 6.1 | GO:0048050 | post-embryonic eye morphogenesis(GO:0048050) |
| 0.6 | 1.9 | GO:0006117 | acetaldehyde metabolic process(GO:0006117) |
| 0.6 | 2.3 | GO:0001971 | negative regulation of activation of membrane attack complex(GO:0001971) |
| 0.5 | 3.8 | GO:0038172 | interleukin-33-mediated signaling pathway(GO:0038172) |
| 0.5 | 4.2 | GO:0032929 | negative regulation of superoxide anion generation(GO:0032929) |
| 0.5 | 5.3 | GO:0042997 | negative regulation of Golgi to plasma membrane protein transport(GO:0042997) |
| 0.5 | 5.7 | GO:0072656 | maintenance of protein location in mitochondrion(GO:0072656) |
| 0.4 | 6.7 | GO:0032119 | sequestering of zinc ion(GO:0032119) |
| 0.4 | 3.5 | GO:0038060 | nitric oxide-cGMP-mediated signaling pathway(GO:0038060) |
| 0.4 | 1.6 | GO:0018277 | protein deamination(GO:0018277) |
| 0.4 | 1.2 | GO:0032747 | positive regulation of interleukin-23 production(GO:0032747) |
| 0.4 | 2.4 | GO:0036518 | chemorepulsion of dopaminergic neuron axon(GO:0036518) |
| 0.4 | 1.2 | GO:0002661 | B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663) |
| 0.4 | 2.4 | GO:1902045 | negative regulation of Fas signaling pathway(GO:1902045) |
| 0.4 | 4.2 | GO:0042905 | 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905) |
| 0.4 | 7.0 | GO:0090179 | planar cell polarity pathway involved in neural tube closure(GO:0090179) |
| 0.4 | 2.5 | GO:2000537 | regulation of cGMP-mediated signaling(GO:0010752) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538) |
| 0.4 | 2.5 | GO:0045229 | cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229) |
| 0.4 | 1.4 | GO:0006617 | SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617) |
| 0.4 | 2.5 | GO:2001288 | positive regulation of caveolin-mediated endocytosis(GO:2001288) |
| 0.3 | 8.1 | GO:0060670 | branching involved in labyrinthine layer morphogenesis(GO:0060670) |
| 0.3 | 3.7 | GO:2000580 | positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582) |
| 0.3 | 2.4 | GO:0061589 | calcium activated phosphatidylserine scrambling(GO:0061589) |
| 0.3 | 0.9 | GO:0021589 | hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589) |
| 0.3 | 3.4 | GO:0090204 | protein localization to nuclear pore(GO:0090204) |
| 0.3 | 0.8 | GO:0055099 | response to high density lipoprotein particle(GO:0055099) |
| 0.3 | 1.4 | GO:0000117 | regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117) |
| 0.3 | 0.5 | GO:0032765 | positive regulation of mast cell cytokine production(GO:0032765) |
| 0.3 | 3.5 | GO:0031580 | membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580) |
| 0.3 | 1.6 | GO:0010193 | response to ozone(GO:0010193) |
| 0.3 | 0.8 | GO:1903371 | regulation of endoplasmic reticulum tubular network organization(GO:1903371) |
| 0.3 | 1.3 | GO:0044339 | canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339) |
| 0.2 | 4.7 | GO:0046007 | negative regulation of activated T cell proliferation(GO:0046007) |
| 0.2 | 3.4 | GO:0015705 | iodide transport(GO:0015705) |
| 0.2 | 1.2 | GO:0035720 | intraciliary anterograde transport(GO:0035720) |
| 0.2 | 2.1 | GO:1900625 | regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625) |
| 0.2 | 1.6 | GO:0014718 | positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718) |
| 0.2 | 2.7 | GO:0014809 | regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809) |
| 0.2 | 2.5 | GO:0070934 | CRD-mediated mRNA stabilization(GO:0070934) |
| 0.2 | 2.6 | GO:0006686 | sphingomyelin biosynthetic process(GO:0006686) |
| 0.2 | 0.9 | GO:0060168 | positive regulation of adenosine receptor signaling pathway(GO:0060168) |
| 0.2 | 0.6 | GO:0007231 | osmosensory signaling pathway(GO:0007231) |
| 0.2 | 0.6 | GO:0001543 | ovarian follicle rupture(GO:0001543) |
| 0.2 | 3.2 | GO:0060315 | negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315) |
| 0.2 | 1.5 | GO:2000574 | regulation of microtubule motor activity(GO:2000574) |
| 0.2 | 0.8 | GO:0033031 | positive regulation of neutrophil apoptotic process(GO:0033031) |
| 0.2 | 1.4 | GO:1902164 | mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164) |
| 0.2 | 0.6 | GO:0061386 | closure of optic fissure(GO:0061386) |
| 0.2 | 1.0 | GO:2001137 | positive regulation of endocytic recycling(GO:2001137) |
| 0.2 | 1.0 | GO:0002296 | T-helper 1 cell lineage commitment(GO:0002296) |
| 0.2 | 0.8 | GO:0035521 | monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522) |
| 0.2 | 0.9 | GO:2000691 | regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691) |
| 0.2 | 1.1 | GO:0070940 | dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940) |
| 0.2 | 1.6 | GO:0060174 | limb bud formation(GO:0060174) |
| 0.2 | 0.9 | GO:0000973 | posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973) |
| 0.2 | 0.9 | GO:0003278 | apoptotic process involved in heart morphogenesis(GO:0003278) |
| 0.2 | 1.7 | GO:2000491 | positive regulation of hepatic stellate cell activation(GO:2000491) |
| 0.2 | 0.9 | GO:0071477 | hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477) |
| 0.2 | 0.5 | GO:0072356 | chromosome passenger complex localization to kinetochore(GO:0072356) |
| 0.2 | 6.0 | GO:0033622 | integrin activation(GO:0033622) |
| 0.2 | 0.2 | GO:0050747 | positive regulation of lipoprotein metabolic process(GO:0050747) positive regulation of protein lipidation(GO:1903061) |
| 0.2 | 1.1 | GO:1902963 | regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963) |
| 0.2 | 7.7 | GO:0006607 | NLS-bearing protein import into nucleus(GO:0006607) |
| 0.2 | 0.5 | GO:0031247 | actin rod assembly(GO:0031247) |
| 0.1 | 1.8 | GO:0006657 | CDP-choline pathway(GO:0006657) |
| 0.1 | 0.7 | GO:0034184 | positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184) |
| 0.1 | 3.1 | GO:0070935 | 3'-UTR-mediated mRNA stabilization(GO:0070935) |
| 0.1 | 1.6 | GO:0031087 | deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087) |
| 0.1 | 1.0 | GO:0046985 | positive regulation of hemoglobin biosynthetic process(GO:0046985) |
| 0.1 | 2.2 | GO:0002934 | desmosome organization(GO:0002934) |
| 0.1 | 1.8 | GO:0006477 | protein sulfation(GO:0006477) |
| 0.1 | 0.4 | GO:0015880 | coenzyme A transport(GO:0015880) coenzyme A transmembrane transport(GO:0035349) adenosine 3',5'-bisphosphate transmembrane transport(GO:0071106) AMP transport(GO:0080121) |
| 0.1 | 1.7 | GO:0060158 | phospholipase C-activating dopamine receptor signaling pathway(GO:0060158) |
| 0.1 | 1.6 | GO:1902570 | protein localization to nucleolus(GO:1902570) |
| 0.1 | 1.9 | GO:0007221 | positive regulation of transcription of Notch receptor target(GO:0007221) |
| 0.1 | 0.4 | GO:0090370 | negative regulation of cholesterol efflux(GO:0090370) |
| 0.1 | 1.2 | GO:0034350 | regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351) |
| 0.1 | 1.3 | GO:0008090 | retrograde axonal transport(GO:0008090) |
| 0.1 | 0.4 | GO:1903060 | regulation of N-terminal protein palmitoylation(GO:0060254) negative regulation of N-terminal protein palmitoylation(GO:0060262) negative regulation of protein lipidation(GO:1903060) |
| 0.1 | 0.2 | GO:2000981 | negative regulation of mechanoreceptor differentiation(GO:0045632) negative regulation of pro-B cell differentiation(GO:2000974) negative regulation of inner ear receptor cell differentiation(GO:2000981) |
| 0.1 | 0.2 | GO:1900226 | negative regulation of NLRP3 inflammasome complex assembly(GO:1900226) |
| 0.1 | 0.6 | GO:0030573 | bile acid catabolic process(GO:0030573) |
| 0.1 | 0.7 | GO:0015722 | canalicular bile acid transport(GO:0015722) |
| 0.1 | 4.1 | GO:0014059 | dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059) |
| 0.1 | 1.9 | GO:2000675 | negative regulation of type B pancreatic cell apoptotic process(GO:2000675) |
| 0.1 | 2.3 | GO:0006703 | estrogen biosynthetic process(GO:0006703) |
| 0.1 | 5.4 | GO:0035774 | positive regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0035774) |
| 0.1 | 0.8 | GO:0072092 | ureteric bud invasion(GO:0072092) |
| 0.1 | 1.2 | GO:0032202 | telomere assembly(GO:0032202) |
| 0.1 | 0.7 | GO:0097428 | protein maturation by iron-sulfur cluster transfer(GO:0097428) |
| 0.1 | 2.7 | GO:0030208 | dermatan sulfate biosynthetic process(GO:0030208) |
| 0.1 | 1.2 | GO:0016080 | synaptic vesicle targeting(GO:0016080) |
| 0.1 | 0.7 | GO:0061732 | mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732) |
| 0.1 | 1.4 | GO:0015871 | choline transport(GO:0015871) |
| 0.1 | 2.4 | GO:0051531 | NFAT protein import into nucleus(GO:0051531) |
| 0.1 | 3.6 | GO:0060441 | epithelial tube branching involved in lung morphogenesis(GO:0060441) |
| 0.1 | 1.7 | GO:0090050 | positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) |
| 0.1 | 2.7 | GO:0010591 | regulation of lamellipodium assembly(GO:0010591) |
| 0.1 | 0.5 | GO:0009449 | gamma-aminobutyric acid biosynthetic process(GO:0009449) |
| 0.1 | 1.3 | GO:0045714 | regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045714) |
| 0.1 | 6.3 | GO:0030835 | negative regulation of actin filament depolymerization(GO:0030835) |
| 0.1 | 0.7 | GO:0017196 | N-terminal peptidyl-methionine acetylation(GO:0017196) |
| 0.1 | 2.2 | GO:0003334 | keratinocyte development(GO:0003334) |
| 0.1 | 0.9 | GO:0010593 | negative regulation of lamellipodium assembly(GO:0010593) |
| 0.1 | 2.1 | GO:0006054 | N-acetylneuraminate metabolic process(GO:0006054) |
| 0.1 | 0.5 | GO:0060161 | peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918) positive regulation of dopamine receptor signaling pathway(GO:0060161) |
| 0.1 | 2.0 | GO:0070816 | phosphorylation of RNA polymerase II C-terminal domain(GO:0070816) |
| 0.1 | 0.2 | GO:0019254 | amino-acid betaine catabolic process(GO:0006579) carnitine metabolic process, CoA-linked(GO:0019254) |
| 0.1 | 0.3 | GO:0051138 | positive regulation of NK T cell differentiation(GO:0051138) |
| 0.1 | 0.7 | GO:0032887 | regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846) |
| 0.1 | 1.3 | GO:0002643 | regulation of tolerance induction(GO:0002643) |
| 0.1 | 1.0 | GO:0038007 | netrin-activated signaling pathway(GO:0038007) |
| 0.1 | 1.0 | GO:0010968 | regulation of microtubule nucleation(GO:0010968) |
| 0.1 | 0.2 | GO:0070781 | arginine biosynthetic process via ornithine(GO:0042450) response to biotin(GO:0070781) |
| 0.1 | 0.7 | GO:0032482 | Rab protein signal transduction(GO:0032482) |
| 0.1 | 1.0 | GO:0006307 | DNA dealkylation involved in DNA repair(GO:0006307) |
| 0.1 | 0.2 | GO:0060330 | regulation of response to interferon-gamma(GO:0060330) |
| 0.1 | 0.6 | GO:0051901 | positive regulation of mitochondrial depolarization(GO:0051901) |
| 0.1 | 0.6 | GO:0006398 | mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398) |
| 0.1 | 1.2 | GO:1900119 | positive regulation of execution phase of apoptosis(GO:1900119) |
| 0.1 | 1.7 | GO:0042481 | regulation of odontogenesis(GO:0042481) |
| 0.1 | 4.1 | GO:0050690 | regulation of defense response to virus by virus(GO:0050690) |
| 0.1 | 0.6 | GO:0003344 | pericardium morphogenesis(GO:0003344) |
| 0.1 | 1.2 | GO:0034384 | high-density lipoprotein particle clearance(GO:0034384) |
| 0.1 | 5.4 | GO:0070830 | bicellular tight junction assembly(GO:0070830) |
| 0.1 | 0.7 | GO:0035385 | Roundabout signaling pathway(GO:0035385) |
| 0.1 | 0.6 | GO:0034398 | telomere tethering at nuclear periphery(GO:0034398) meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240) |
| 0.1 | 5.5 | GO:0042795 | snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795) |
| 0.1 | 0.2 | GO:0035995 | detection of muscle stretch(GO:0035995) |
| 0.1 | 0.7 | GO:2001013 | epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013) |
| 0.1 | 1.8 | GO:0032958 | inositol phosphate biosynthetic process(GO:0032958) |
| 0.1 | 0.2 | GO:0031081 | nuclear pore distribution(GO:0031081) nuclear pore localization(GO:0051664) |
| 0.0 | 4.2 | GO:0001954 | positive regulation of cell-matrix adhesion(GO:0001954) |
| 0.0 | 0.4 | GO:0006049 | UDP-N-acetylglucosamine catabolic process(GO:0006049) |
| 0.0 | 0.2 | GO:0032497 | detection of lipopolysaccharide(GO:0032497) |
| 0.0 | 0.8 | GO:0006370 | 7-methylguanosine mRNA capping(GO:0006370) |
| 0.0 | 1.5 | GO:0010800 | positive regulation of peptidyl-threonine phosphorylation(GO:0010800) |
| 0.0 | 1.0 | GO:0051315 | attachment of mitotic spindle microtubules to kinetochore(GO:0051315) |
| 0.0 | 0.8 | GO:0060056 | mammary gland involution(GO:0060056) |
| 0.0 | 1.1 | GO:0046519 | sphingoid metabolic process(GO:0046519) |
| 0.0 | 1.8 | GO:0018345 | protein palmitoylation(GO:0018345) |
| 0.0 | 0.2 | GO:0002018 | renin-angiotensin regulation of aldosterone production(GO:0002018) |
| 0.0 | 0.7 | GO:1900364 | negative regulation of mRNA polyadenylation(GO:1900364) |
| 0.0 | 1.0 | GO:0030183 | B cell differentiation(GO:0030183) |
| 0.0 | 1.6 | GO:0042554 | superoxide anion generation(GO:0042554) |
| 0.0 | 0.2 | GO:1902896 | terminal web assembly(GO:1902896) |
| 0.0 | 0.2 | GO:0097498 | endothelial tube lumen extension(GO:0097498) |
| 0.0 | 0.5 | GO:1990118 | sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118) |
| 0.0 | 2.9 | GO:0061001 | regulation of dendritic spine morphogenesis(GO:0061001) |
| 0.0 | 3.9 | GO:0046847 | filopodium assembly(GO:0046847) |
| 0.0 | 0.2 | GO:0052551 | response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565) |
| 0.0 | 1.2 | GO:0001580 | detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580) |
| 0.0 | 0.5 | GO:0048711 | positive regulation of astrocyte differentiation(GO:0048711) |
| 0.0 | 2.9 | GO:0006027 | glycosaminoglycan catabolic process(GO:0006027) |
| 0.0 | 1.0 | GO:0001701 | in utero embryonic development(GO:0001701) |
| 0.0 | 0.3 | GO:0051451 | myoblast migration(GO:0051451) |
| 0.0 | 0.8 | GO:0006363 | termination of RNA polymerase I transcription(GO:0006363) |
| 0.0 | 0.8 | GO:0035855 | megakaryocyte development(GO:0035855) |
| 0.0 | 0.2 | GO:0010966 | regulation of phosphate transport(GO:0010966) |
| 0.0 | 0.7 | GO:0050908 | detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962) |
| 0.0 | 0.9 | GO:0035455 | response to interferon-alpha(GO:0035455) |
| 0.0 | 0.7 | GO:0032376 | positive regulation of sterol transport(GO:0032373) positive regulation of cholesterol transport(GO:0032376) |
| 0.0 | 0.4 | GO:0045793 | positive regulation of cell size(GO:0045793) |
| 0.0 | 1.3 | GO:0006409 | tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431) |
| 0.0 | 0.1 | GO:1903301 | positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301) |
| 0.0 | 0.3 | GO:0006528 | asparagine metabolic process(GO:0006528) |
| 0.0 | 1.2 | GO:0019433 | triglyceride catabolic process(GO:0019433) |
| 0.0 | 0.8 | GO:0043552 | positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552) |
| 0.0 | 3.7 | GO:0060333 | interferon-gamma-mediated signaling pathway(GO:0060333) |
| 0.0 | 4.0 | GO:1902476 | chloride transmembrane transport(GO:1902476) |
| 0.0 | 0.7 | GO:0071732 | cellular response to nitric oxide(GO:0071732) |
| 0.0 | 1.1 | GO:0031122 | cytoplasmic microtubule organization(GO:0031122) |
| 0.0 | 0.1 | GO:0032431 | positive regulation of phospholipase A2 activity(GO:0032430) activation of phospholipase A2 activity(GO:0032431) |
| 0.0 | 0.4 | GO:1904354 | negative regulation of telomere capping(GO:1904354) |
| 0.0 | 1.1 | GO:0032456 | endocytic recycling(GO:0032456) |
| 0.0 | 0.7 | GO:0046174 | polyol catabolic process(GO:0046174) |
| 0.0 | 0.2 | GO:0046464 | neutral lipid catabolic process(GO:0046461) acylglycerol catabolic process(GO:0046464) |
| 0.0 | 1.1 | GO:0018149 | peptide cross-linking(GO:0018149) |
| 0.0 | 1.9 | GO:0001895 | retina homeostasis(GO:0001895) |
| 0.0 | 0.4 | GO:0034975 | protein folding in endoplasmic reticulum(GO:0034975) |
| 0.0 | 0.7 | GO:0003351 | epithelial cilium movement(GO:0003351) |
| 0.0 | 0.1 | GO:0010446 | response to alkaline pH(GO:0010446) detection of mechanical stimulus involved in sensory perception of touch(GO:0050976) cellular response to alkaline pH(GO:0071469) |
| 0.0 | 0.2 | GO:0007185 | transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185) |
| 0.0 | 0.7 | GO:0032011 | ARF protein signal transduction(GO:0032011) |
| 0.0 | 0.3 | GO:0006782 | protoporphyrinogen IX biosynthetic process(GO:0006782) |
| 0.0 | 3.2 | GO:0060071 | Wnt signaling pathway, planar cell polarity pathway(GO:0060071) |
| 0.0 | 0.1 | GO:1903525 | regulation of membrane tubulation(GO:1903525) positive regulation of membrane tubulation(GO:1903527) |
| 0.0 | 1.8 | GO:0006611 | protein export from nucleus(GO:0006611) |
| 0.0 | 0.3 | GO:2000324 | positive regulation of glucocorticoid receptor signaling pathway(GO:2000324) |
| 0.0 | 0.1 | GO:2000510 | positive regulation of sperm motility involved in capacitation(GO:0060474) positive regulation of dendritic cell chemotaxis(GO:2000510) |
| 0.0 | 2.4 | GO:0002223 | stimulatory C-type lectin receptor signaling pathway(GO:0002223) |
| 0.0 | 1.9 | GO:0090502 | RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502) |
| 0.0 | 0.3 | GO:0001955 | blood vessel maturation(GO:0001955) |
| 0.0 | 1.3 | GO:0030166 | proteoglycan biosynthetic process(GO:0030166) |
| 0.0 | 0.7 | GO:2000272 | negative regulation of receptor activity(GO:2000272) |
| 0.0 | 0.2 | GO:0002430 | complement receptor mediated signaling pathway(GO:0002430) |
| 0.0 | 0.5 | GO:0030855 | epithelial cell differentiation(GO:0030855) |
| 0.0 | 0.5 | GO:0035435 | phosphate ion transmembrane transport(GO:0035435) |
| 0.0 | 3.8 | GO:0035023 | regulation of Rho protein signal transduction(GO:0035023) |
| 0.0 | 1.3 | GO:0000289 | nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289) |
| 0.0 | 0.7 | GO:0035196 | production of miRNAs involved in gene silencing by miRNA(GO:0035196) |
| 0.0 | 0.5 | GO:0051290 | protein heterotetramerization(GO:0051290) |
| 0.0 | 0.2 | GO:0000717 | nucleotide-excision repair, DNA duplex unwinding(GO:0000717) |
| 0.0 | 0.2 | GO:0009954 | proximal/distal pattern formation(GO:0009954) |
| 0.0 | 1.3 | GO:0007032 | endosome organization(GO:0007032) |
| 0.0 | 1.9 | GO:0033209 | tumor necrosis factor-mediated signaling pathway(GO:0033209) |
| 0.0 | 0.2 | GO:0015824 | proline transport(GO:0015824) |
| 0.0 | 0.7 | GO:0000413 | protein peptidyl-prolyl isomerization(GO:0000413) |
| 0.0 | 0.6 | GO:0030488 | tRNA methylation(GO:0030488) |
| 0.0 | 0.3 | GO:0043086 | negative regulation of catalytic activity(GO:0043086) |
| 0.0 | 0.2 | GO:1990823 | response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830) |
| 0.0 | 0.3 | GO:0014898 | muscle hypertrophy in response to stress(GO:0003299) cardiac muscle adaptation(GO:0014887) cardiac muscle hypertrophy in response to stress(GO:0014898) |
| 0.0 | 0.0 | GO:0061056 | sclerotome development(GO:0061056) |
| 0.0 | 0.5 | GO:0017144 | drug metabolic process(GO:0017144) |
| 0.0 | 1.3 | GO:0045727 | positive regulation of translation(GO:0045727) |
| 0.0 | 0.1 | GO:0032926 | negative regulation of activin receptor signaling pathway(GO:0032926) |
| 0.0 | 0.2 | GO:0015074 | DNA integration(GO:0015074) |
| 0.0 | 0.1 | GO:0045617 | negative regulation of epidermal cell differentiation(GO:0045605) negative regulation of keratinocyte differentiation(GO:0045617) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 5.6 | GO:0070876 | SOSS complex(GO:0070876) |
| 0.6 | 3.2 | GO:1990425 | ryanodine receptor complex(GO:1990425) |
| 0.6 | 1.9 | GO:0035525 | NF-kappaB p50/p65 complex(GO:0035525) |
| 0.4 | 5.4 | GO:0061689 | tricellular tight junction(GO:0061689) |
| 0.4 | 2.4 | GO:0000308 | cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308) |
| 0.4 | 1.1 | GO:0034515 | proteasome storage granule(GO:0034515) |
| 0.3 | 3.5 | GO:0005593 | FACIT collagen trimer(GO:0005593) |
| 0.3 | 2.5 | GO:0016013 | syntrophin complex(GO:0016013) |
| 0.3 | 1.1 | GO:1990745 | EARP complex(GO:1990745) |
| 0.3 | 2.4 | GO:1990578 | perinuclear endoplasmic reticulum membrane(GO:1990578) |
| 0.3 | 2.1 | GO:0035692 | macrophage migration inhibitory factor receptor complex(GO:0035692) |
| 0.3 | 0.8 | GO:0005668 | RNA polymerase transcription factor SL1 complex(GO:0005668) |
| 0.2 | 2.5 | GO:0071204 | histone pre-mRNA 3'end processing complex(GO:0071204) |
| 0.2 | 18.3 | GO:0001533 | cornified envelope(GO:0001533) |
| 0.2 | 0.7 | GO:0036195 | muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195) |
| 0.2 | 6.1 | GO:0001527 | microfibril(GO:0001527) fibril(GO:0043205) |
| 0.2 | 1.3 | GO:0031673 | H zone(GO:0031673) |
| 0.2 | 0.9 | GO:0097232 | lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233) |
| 0.2 | 1.8 | GO:0032010 | phagolysosome(GO:0032010) |
| 0.2 | 1.1 | GO:0010370 | perinucleolar chromocenter(GO:0010370) |
| 0.2 | 2.0 | GO:0000439 | core TFIIH complex(GO:0000439) |
| 0.2 | 4.7 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
| 0.2 | 1.1 | GO:0070381 | endosome to plasma membrane transport vesicle(GO:0070381) |
| 0.2 | 6.6 | GO:0032839 | dendrite cytoplasm(GO:0032839) |
| 0.2 | 2.2 | GO:0030057 | desmosome(GO:0030057) |
| 0.2 | 0.5 | GO:1990015 | mesaxon(GO:0097453) ensheathing process(GO:1990015) |
| 0.2 | 6.8 | GO:0097228 | sperm principal piece(GO:0097228) |
| 0.1 | 7.6 | GO:0009925 | basal plasma membrane(GO:0009925) |
| 0.1 | 5.4 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
| 0.1 | 1.8 | GO:0042587 | glycogen granule(GO:0042587) |
| 0.1 | 0.9 | GO:0044614 | nuclear pore cytoplasmic filaments(GO:0044614) |
| 0.1 | 1.4 | GO:0005786 | signal recognition particle, endoplasmic reticulum targeting(GO:0005786) |
| 0.1 | 3.7 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
| 0.1 | 0.5 | GO:0032449 | CBM complex(GO:0032449) |
| 0.1 | 1.2 | GO:0070022 | transforming growth factor beta receptor homodimeric complex(GO:0070022) |
| 0.1 | 0.7 | GO:0035061 | interchromatin granule(GO:0035061) |
| 0.1 | 2.5 | GO:0017146 | NMDA selective glutamate receptor complex(GO:0017146) |
| 0.1 | 8.2 | GO:0030669 | clathrin-coated endocytic vesicle membrane(GO:0030669) |
| 0.1 | 1.0 | GO:0098559 | cytoplasmic side of early endosome membrane(GO:0098559) cytoplasmic side of late endosome membrane(GO:0098560) |
| 0.1 | 0.7 | GO:0031415 | NatA complex(GO:0031415) |
| 0.1 | 3.5 | GO:0005697 | telomerase holoenzyme complex(GO:0005697) |
| 0.1 | 0.4 | GO:0005846 | nuclear cap binding complex(GO:0005846) |
| 0.1 | 2.4 | GO:0035145 | exon-exon junction complex(GO:0035145) |
| 0.1 | 12.8 | GO:0097517 | stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517) |
| 0.1 | 2.1 | GO:0031362 | anchored component of external side of plasma membrane(GO:0031362) |
| 0.1 | 0.7 | GO:0055028 | cortical microtubule(GO:0055028) |
| 0.1 | 1.0 | GO:0031105 | septin complex(GO:0031105) |
| 0.1 | 0.7 | GO:0045254 | pyruvate dehydrogenase complex(GO:0045254) |
| 0.1 | 2.5 | GO:0005868 | cytoplasmic dynein complex(GO:0005868) |
| 0.1 | 0.3 | GO:0014802 | terminal cisterna(GO:0014802) |
| 0.1 | 1.5 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 0.1 | 3.1 | GO:0005605 | basal lamina(GO:0005605) |
| 0.1 | 1.0 | GO:0000778 | condensed nuclear chromosome kinetochore(GO:0000778) |
| 0.1 | 0.6 | GO:0042788 | polysomal ribosome(GO:0042788) |
| 0.1 | 0.9 | GO:0005740 | mitochondrial envelope(GO:0005740) |
| 0.1 | 1.1 | GO:0032433 | filopodium tip(GO:0032433) |
| 0.1 | 0.7 | GO:0046581 | intercellular canaliculus(GO:0046581) |
| 0.1 | 1.3 | GO:0034663 | endoplasmic reticulum chaperone complex(GO:0034663) |
| 0.1 | 1.3 | GO:0030127 | COPII vesicle coat(GO:0030127) |
| 0.1 | 0.8 | GO:0034518 | mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518) |
| 0.0 | 0.4 | GO:0005971 | ribonucleoside-diphosphate reductase complex(GO:0005971) |
| 0.0 | 1.5 | GO:0030014 | CCR4-NOT complex(GO:0030014) |
| 0.0 | 0.2 | GO:0046696 | lipopolysaccharide receptor complex(GO:0046696) |
| 0.0 | 0.2 | GO:0071942 | XPC complex(GO:0071942) |
| 0.0 | 2.0 | GO:0034451 | centriolar satellite(GO:0034451) |
| 0.0 | 3.5 | GO:0016235 | aggresome(GO:0016235) |
| 0.0 | 1.0 | GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671) |
| 0.0 | 2.6 | GO:0005771 | multivesicular body(GO:0005771) |
| 0.0 | 2.3 | GO:0002102 | podosome(GO:0002102) |
| 0.0 | 0.5 | GO:0034709 | methylosome(GO:0034709) |
| 0.0 | 1.1 | GO:0031258 | lamellipodium membrane(GO:0031258) |
| 0.0 | 0.2 | GO:1990357 | terminal web(GO:1990357) |
| 0.0 | 0.7 | GO:0005892 | acetylcholine-gated channel complex(GO:0005892) |
| 0.0 | 0.7 | GO:0000974 | Prp19 complex(GO:0000974) |
| 0.0 | 0.2 | GO:0097524 | sperm plasma membrane(GO:0097524) |
| 0.0 | 3.1 | GO:0005604 | basement membrane(GO:0005604) |
| 0.0 | 3.7 | GO:0005643 | nuclear pore(GO:0005643) |
| 0.0 | 1.2 | GO:0034364 | high-density lipoprotein particle(GO:0034364) |
| 0.0 | 2.0 | GO:0005871 | kinesin complex(GO:0005871) |
| 0.0 | 12.1 | GO:0031965 | nuclear membrane(GO:0031965) |
| 0.0 | 0.6 | GO:0005847 | mRNA cleavage and polyadenylation specificity factor complex(GO:0005847) |
| 0.0 | 2.3 | GO:0005791 | rough endoplasmic reticulum(GO:0005791) |
| 0.0 | 1.2 | GO:0097542 | ciliary tip(GO:0097542) |
| 0.0 | 1.8 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
| 0.0 | 2.3 | GO:0005905 | clathrin-coated pit(GO:0005905) |
| 0.0 | 12.6 | GO:0045177 | apical part of cell(GO:0045177) |
| 0.0 | 0.5 | GO:0005832 | chaperonin-containing T-complex(GO:0005832) |
| 0.0 | 0.4 | GO:0035371 | microtubule plus-end(GO:0035371) |
| 0.0 | 4.5 | GO:0045111 | intermediate filament cytoskeleton(GO:0045111) |
| 0.0 | 2.2 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 0.0 | 2.9 | GO:0000932 | cytoplasmic mRNA processing body(GO:0000932) |
| 0.0 | 1.8 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
| 0.0 | 5.1 | GO:0001726 | ruffle(GO:0001726) |
| 0.0 | 1.5 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
| 0.0 | 0.1 | GO:0044306 | neuron projection terminus(GO:0044306) |
| 0.0 | 1.1 | GO:0030315 | T-tubule(GO:0030315) |
| 0.0 | 0.5 | GO:0005838 | proteasome regulatory particle(GO:0005838) |
| 0.0 | 1.4 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
| 0.0 | 0.6 | GO:0030027 | lamellipodium(GO:0030027) |
| 0.0 | 1.1 | GO:0005903 | brush border(GO:0005903) |
| 0.0 | 0.6 | GO:0044295 | axonal growth cone(GO:0044295) |
| 0.0 | 0.4 | GO:0005942 | phosphatidylinositol 3-kinase complex(GO:0005942) |
| 0.0 | 4.9 | GO:0009897 | external side of plasma membrane(GO:0009897) |
| 0.0 | 0.7 | GO:0080008 | Cul4-RING E3 ubiquitin ligase complex(GO:0080008) |
| 0.0 | 1.0 | GO:0045171 | intercellular bridge(GO:0045171) |
| 0.0 | 1.0 | GO:0031594 | neuromuscular junction(GO:0031594) |
| 0.0 | 0.1 | GO:0061695 | transferase complex, transferring phosphorus-containing groups(GO:0061695) |
| 0.0 | 0.2 | GO:0070187 | telosome(GO:0070187) |
| 0.0 | 0.8 | GO:0030672 | synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501) |
| 0.0 | 2.6 | GO:0001650 | fibrillar center(GO:0001650) |
| 0.0 | 0.3 | GO:0044298 | neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298) |
| 0.0 | 0.7 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
| 0.0 | 1.2 | GO:0005811 | lipid particle(GO:0005811) |
| 0.0 | 0.7 | GO:0015030 | Cajal body(GO:0015030) |
| 0.0 | 0.1 | GO:0043564 | Ku70:Ku80 complex(GO:0043564) |
| 0.0 | 0.5 | GO:0030529 | intracellular ribonucleoprotein complex(GO:0030529) ribonucleoprotein complex(GO:1990904) |
| 0.0 | 0.7 | GO:0005782 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.0 | 14.2 | GO:0035662 | Toll-like receptor 4 binding(GO:0035662) |
| 1.4 | 4.3 | GO:0016964 | alpha-2 macroglobulin receptor activity(GO:0016964) |
| 1.3 | 3.8 | GO:0002113 | interleukin-33 binding(GO:0002113) |
| 1.1 | 5.4 | GO:0060961 | phospholipase D inhibitor activity(GO:0060961) |
| 0.8 | 9.4 | GO:0086083 | cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083) |
| 0.7 | 6.4 | GO:0019158 | glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158) |
| 0.6 | 15.6 | GO:0045499 | chemorepellent activity(GO:0045499) |
| 0.5 | 2.7 | GO:0047757 | chondroitin-glucuronate 5-epimerase activity(GO:0047757) |
| 0.5 | 3.9 | GO:0004064 | arylesterase activity(GO:0004064) |
| 0.5 | 6.8 | GO:0047035 | testosterone dehydrogenase (NAD+) activity(GO:0047035) |
| 0.4 | 2.5 | GO:0043423 | 3-phosphoinositide-dependent protein kinase binding(GO:0043423) |
| 0.4 | 14.3 | GO:0005229 | intracellular calcium activated chloride channel activity(GO:0005229) |
| 0.4 | 5.5 | GO:0098599 | palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599) |
| 0.4 | 2.6 | GO:0033188 | sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493) |
| 0.4 | 1.8 | GO:0004105 | choline-phosphate cytidylyltransferase activity(GO:0004105) |
| 0.3 | 3.4 | GO:0071532 | ankyrin repeat binding(GO:0071532) |
| 0.3 | 2.1 | GO:0004522 | ribonuclease A activity(GO:0004522) |
| 0.3 | 1.2 | GO:0005026 | transforming growth factor beta receptor activity, type II(GO:0005026) |
| 0.3 | 5.3 | GO:0008199 | ferric iron binding(GO:0008199) |
| 0.3 | 4.4 | GO:0008097 | 5S rRNA binding(GO:0008097) |
| 0.3 | 0.8 | GO:0034041 | sterol-transporting ATPase activity(GO:0034041) |
| 0.3 | 1.4 | GO:0052839 | inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839) |
| 0.3 | 2.4 | GO:1904929 | coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929) |
| 0.3 | 3.6 | GO:0003810 | protein-glutamine gamma-glutamyltransferase activity(GO:0003810) |
| 0.3 | 1.8 | GO:0050119 | N-acetylglucosamine deacetylase activity(GO:0050119) |
| 0.2 | 9.1 | GO:0043325 | phosphatidylinositol-3,4-bisphosphate binding(GO:0043325) |
| 0.2 | 1.7 | GO:0031826 | type 2A serotonin receptor binding(GO:0031826) |
| 0.2 | 0.7 | GO:0070538 | oleic acid binding(GO:0070538) |
| 0.2 | 0.9 | GO:0050698 | proteoglycan sulfotransferase activity(GO:0050698) |
| 0.2 | 3.1 | GO:1990247 | N6-methyladenosine-containing RNA binding(GO:1990247) |
| 0.2 | 0.7 | GO:0015432 | bile acid-exporting ATPase activity(GO:0015432) |
| 0.2 | 0.9 | GO:0052642 | lysophosphatidic acid phosphatase activity(GO:0052642) |
| 0.2 | 0.6 | GO:0030366 | molybdopterin synthase activity(GO:0030366) |
| 0.2 | 0.6 | GO:0050146 | nucleoside phosphotransferase activity(GO:0050146) |
| 0.2 | 3.5 | GO:0019911 | structural constituent of myelin sheath(GO:0019911) |
| 0.2 | 1.0 | GO:0004556 | alpha-amylase activity(GO:0004556) |
| 0.2 | 4.7 | GO:0008603 | cAMP-dependent protein kinase regulator activity(GO:0008603) |
| 0.2 | 3.5 | GO:0031852 | mu-type opioid receptor binding(GO:0031852) |
| 0.2 | 3.2 | GO:0019855 | calcium channel inhibitor activity(GO:0019855) type I transforming growth factor beta receptor binding(GO:0034713) |
| 0.2 | 4.6 | GO:0008353 | RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353) |
| 0.2 | 1.2 | GO:0004699 | calcium-independent protein kinase C activity(GO:0004699) |
| 0.2 | 2.4 | GO:0043125 | ErbB-3 class receptor binding(GO:0043125) |
| 0.2 | 1.9 | GO:0010859 | calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859) |
| 0.2 | 2.9 | GO:0032395 | MHC class II receptor activity(GO:0032395) |
| 0.2 | 1.0 | GO:0004096 | catalase activity(GO:0004096) |
| 0.2 | 3.7 | GO:0045504 | dynein heavy chain binding(GO:0045504) |
| 0.2 | 1.4 | GO:0030942 | endoplasmic reticulum signal peptide binding(GO:0030942) |
| 0.2 | 1.4 | GO:0015220 | choline transmembrane transporter activity(GO:0015220) |
| 0.2 | 2.5 | GO:0019870 | potassium channel inhibitor activity(GO:0019870) |
| 0.2 | 0.6 | GO:0004492 | methylmalonyl-CoA decarboxylase activity(GO:0004492) |
| 0.1 | 1.6 | GO:0003847 | 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847) |
| 0.1 | 1.6 | GO:0019834 | phospholipase A2 inhibitor activity(GO:0019834) |
| 0.1 | 0.4 | GO:0015228 | coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122) |
| 0.1 | 0.9 | GO:0051022 | GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022) |
| 0.1 | 5.4 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
| 0.1 | 7.6 | GO:0004693 | cyclin-dependent protein serine/threonine kinase activity(GO:0004693) |
| 0.1 | 4.3 | GO:0070273 | phosphatidylinositol-4-phosphate binding(GO:0070273) |
| 0.1 | 3.2 | GO:0031005 | filamin binding(GO:0031005) |
| 0.1 | 1.8 | GO:0016176 | superoxide-generating NADPH oxidase activator activity(GO:0016176) |
| 0.1 | 0.3 | GO:0004853 | uroporphyrinogen decarboxylase activity(GO:0004853) |
| 0.1 | 2.5 | GO:0050998 | nitric-oxide synthase binding(GO:0050998) |
| 0.1 | 3.7 | GO:0004383 | guanylate cyclase activity(GO:0004383) |
| 0.1 | 5.0 | GO:0050750 | low-density lipoprotein particle receptor binding(GO:0050750) |
| 0.1 | 6.9 | GO:0001784 | phosphotyrosine binding(GO:0001784) |
| 0.1 | 0.8 | GO:0052723 | inositol-1,3,4,5,6-pentakisphosphate kinase activity(GO:0000827) inositol hexakisphosphate kinase activity(GO:0000828) inositol heptakisphosphate kinase activity(GO:0000829) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724) |
| 0.1 | 6.2 | GO:0003785 | actin monomer binding(GO:0003785) |
| 0.1 | 0.8 | GO:0008174 | mRNA methyltransferase activity(GO:0008174) |
| 0.1 | 1.1 | GO:0060002 | plus-end directed microfilament motor activity(GO:0060002) |
| 0.1 | 0.4 | GO:0030550 | acetylcholine receptor inhibitor activity(GO:0030550) |
| 0.1 | 0.6 | GO:0004809 | tRNA (guanine-N2-)-methyltransferase activity(GO:0004809) |
| 0.1 | 0.2 | GO:0005168 | neurotrophin TRKA receptor binding(GO:0005168) |
| 0.1 | 1.7 | GO:0001206 | transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206) |
| 0.1 | 1.6 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
| 0.1 | 1.0 | GO:0019237 | centromeric DNA binding(GO:0019237) |
| 0.1 | 0.7 | GO:0034604 | pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604) |
| 0.1 | 1.1 | GO:0008420 | CTD phosphatase activity(GO:0008420) |
| 0.1 | 0.3 | GO:0001069 | regulatory region RNA binding(GO:0001069) |
| 0.1 | 0.7 | GO:0008172 | S-methyltransferase activity(GO:0008172) |
| 0.1 | 1.0 | GO:0030274 | LIM domain binding(GO:0030274) |
| 0.1 | 1.5 | GO:0032794 | GTPase activating protein binding(GO:0032794) |
| 0.1 | 1.8 | GO:0051371 | muscle alpha-actinin binding(GO:0051371) |
| 0.1 | 1.5 | GO:0032052 | bile acid binding(GO:0032052) |
| 0.1 | 1.6 | GO:0003836 | beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836) |
| 0.1 | 0.5 | GO:0035243 | protein-arginine omega-N symmetric methyltransferase activity(GO:0035243) |
| 0.1 | 0.2 | GO:0016401 | palmitoyl-CoA oxidase activity(GO:0016401) |
| 0.1 | 0.8 | GO:0035005 | 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005) |
| 0.1 | 0.7 | GO:0048495 | Roundabout binding(GO:0048495) |
| 0.1 | 3.1 | GO:0030742 | GTP-dependent protein binding(GO:0030742) |
| 0.1 | 1.6 | GO:0031432 | titin binding(GO:0031432) |
| 0.1 | 2.6 | GO:0001848 | complement binding(GO:0001848) |
| 0.1 | 0.2 | GO:0008511 | sodium:potassium:chloride symporter activity(GO:0008511) |
| 0.1 | 0.7 | GO:0019864 | IgG binding(GO:0019864) |
| 0.1 | 3.1 | GO:0008536 | Ran GTPase binding(GO:0008536) |
| 0.1 | 5.6 | GO:0005044 | scavenger receptor activity(GO:0005044) |
| 0.1 | 0.6 | GO:0072542 | protein phosphatase activator activity(GO:0072542) |
| 0.1 | 1.6 | GO:0016641 | oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641) |
| 0.1 | 0.8 | GO:0015379 | potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820) |
| 0.1 | 0.2 | GO:0032795 | heterotrimeric G-protein binding(GO:0032795) |
| 0.1 | 2.4 | GO:0005123 | death receptor binding(GO:0005123) |
| 0.1 | 1.6 | GO:0005402 | sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) |
| 0.1 | 1.9 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 0.1 | 2.0 | GO:0008143 | poly(A) binding(GO:0008143) |
| 0.1 | 0.5 | GO:0015501 | glutamate:sodium symporter activity(GO:0015501) |
| 0.1 | 1.7 | GO:0031078 | histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) |
| 0.1 | 2.1 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
| 0.0 | 0.4 | GO:0003827 | alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827) |
| 0.0 | 6.9 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.0 | 0.4 | GO:0001517 | N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) |
| 0.0 | 1.8 | GO:0019707 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707) |
| 0.0 | 1.0 | GO:0008432 | JUN kinase binding(GO:0008432) |
| 0.0 | 2.0 | GO:0005031 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
| 0.0 | 1.8 | GO:0051059 | NF-kappaB binding(GO:0051059) |
| 0.0 | 8.7 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
| 0.0 | 0.5 | GO:0005068 | transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068) |
| 0.0 | 0.9 | GO:0008320 | protein transmembrane transporter activity(GO:0008320) |
| 0.0 | 0.9 | GO:0051787 | misfolded protein binding(GO:0051787) |
| 0.0 | 0.5 | GO:0015386 | potassium:proton antiporter activity(GO:0015386) |
| 0.0 | 3.5 | GO:0008565 | protein transporter activity(GO:0008565) |
| 0.0 | 0.4 | GO:0000340 | RNA 7-methylguanosine cap binding(GO:0000340) |
| 0.0 | 0.1 | GO:0004060 | arylamine N-acetyltransferase activity(GO:0004060) |
| 0.0 | 0.6 | GO:0004596 | peptide alpha-N-acetyltransferase activity(GO:0004596) |
| 0.0 | 0.2 | GO:0001875 | lipopolysaccharide receptor activity(GO:0001875) |
| 0.0 | 0.2 | GO:0031433 | telethonin binding(GO:0031433) |
| 0.0 | 1.4 | GO:1990841 | promoter-specific chromatin binding(GO:1990841) |
| 0.0 | 0.1 | GO:0098782 | mechanically-gated potassium channel activity(GO:0098782) |
| 0.0 | 0.6 | GO:0035259 | glucocorticoid receptor binding(GO:0035259) |
| 0.0 | 4.6 | GO:0031490 | chromatin DNA binding(GO:0031490) |
| 0.0 | 0.9 | GO:0051537 | 2 iron, 2 sulfur cluster binding(GO:0051537) |
| 0.0 | 0.6 | GO:0005487 | nucleocytoplasmic transporter activity(GO:0005487) |
| 0.0 | 0.1 | GO:0070095 | fructose-6-phosphate binding(GO:0070095) |
| 0.0 | 1.8 | GO:0042162 | telomeric DNA binding(GO:0042162) |
| 0.0 | 0.4 | GO:0045236 | CXCR chemokine receptor binding(GO:0045236) |
| 0.0 | 0.5 | GO:0005436 | sodium:phosphate symporter activity(GO:0005436) |
| 0.0 | 0.3 | GO:0004859 | phospholipase inhibitor activity(GO:0004859) |
| 0.0 | 8.6 | GO:0044822 | mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822) |
| 0.0 | 0.8 | GO:0000980 | RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980) |
| 0.0 | 0.1 | GO:0004711 | ribosomal protein S6 kinase activity(GO:0004711) |
| 0.0 | 0.7 | GO:0005092 | GDP-dissociation inhibitor activity(GO:0005092) |
| 0.0 | 0.4 | GO:0034185 | apolipoprotein binding(GO:0034185) |
| 0.0 | 1.0 | GO:0005547 | phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547) |
| 0.0 | 0.7 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
| 0.0 | 1.6 | GO:0019003 | GDP binding(GO:0019003) |
| 0.0 | 1.8 | GO:0035064 | methylated histone binding(GO:0035064) |
| 0.0 | 0.8 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity(GO:0004198) |
| 0.0 | 0.2 | GO:0005328 | neurotransmitter:sodium symporter activity(GO:0005328) |
| 0.0 | 1.7 | GO:0001618 | virus receptor activity(GO:0001618) |
| 0.0 | 1.4 | GO:0004712 | protein serine/threonine/tyrosine kinase activity(GO:0004712) |
| 0.0 | 1.0 | GO:0050699 | WW domain binding(GO:0050699) |
| 0.0 | 0.1 | GO:0008336 | gamma-butyrobetaine dioxygenase activity(GO:0008336) |
| 0.0 | 0.6 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
| 0.0 | 1.2 | GO:0002039 | p53 binding(GO:0002039) |
| 0.0 | 0.6 | GO:0008395 | steroid hydroxylase activity(GO:0008395) |
| 0.0 | 0.7 | GO:0003755 | peptidyl-prolyl cis-trans isomerase activity(GO:0003755) |
| 0.0 | 0.4 | GO:0102391 | decanoate--CoA ligase activity(GO:0102391) |
| 0.0 | 0.2 | GO:0019531 | oxalate transmembrane transporter activity(GO:0019531) |
| 0.0 | 0.1 | GO:0031013 | troponin I binding(GO:0031013) |
| 0.0 | 0.7 | GO:0008307 | structural constituent of muscle(GO:0008307) |
| 0.0 | 0.2 | GO:0004707 | MAP kinase activity(GO:0004707) |
| 0.0 | 0.3 | GO:0005251 | delayed rectifier potassium channel activity(GO:0005251) |
| 0.0 | 0.3 | GO:0003995 | acyl-CoA dehydrogenase activity(GO:0003995) |
| 0.0 | 0.2 | GO:0047372 | acylglycerol lipase activity(GO:0047372) |
| 0.0 | 0.1 | GO:0019957 | C-C chemokine binding(GO:0019957) |
| 0.0 | 0.3 | GO:0070001 | aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 14.5 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
| 0.2 | 13.4 | PID ALPHA SYNUCLEIN PATHWAY | Alpha-synuclein signaling |
| 0.1 | 1.7 | ST PAC1 RECEPTOR PATHWAY | PAC1 Receptor Pathway |
| 0.1 | 4.3 | PID NFKAPPAB ATYPICAL PATHWAY | Atypical NF-kappaB pathway |
| 0.1 | 6.7 | PID FRA PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
| 0.1 | 23.5 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.1 | 2.9 | PID AVB3 OPN PATHWAY | Osteopontin-mediated events |
| 0.1 | 4.6 | PID IL12 STAT4 PATHWAY | IL12 signaling mediated by STAT4 |
| 0.1 | 8.5 | PID TAP63 PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 0.1 | 6.3 | PID ECADHERIN STABILIZATION PATHWAY | Stabilization and expansion of the E-cadherin adherens junction |
| 0.1 | 5.7 | PID INTEGRIN A4B1 PATHWAY | Alpha4 beta1 integrin signaling events |
| 0.1 | 4.5 | PID PI3KCI PATHWAY | Class I PI3K signaling events |
| 0.1 | 1.2 | PID GMCSF PATHWAY | GMCSF-mediated signaling events |
| 0.1 | 2.4 | PID WNT SIGNALING PATHWAY | Wnt signaling network |
| 0.1 | 1.7 | SA B CELL RECEPTOR COMPLEXES | Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases. |
| 0.1 | 3.2 | PID PTP1B PATHWAY | Signaling events mediated by PTP1B |
| 0.1 | 4.3 | PID TCR PATHWAY | TCR signaling in naïve CD4+ T cells |
| 0.1 | 1.0 | SIG IL4RECEPTOR IN B LYPHOCYTES | Genes related to IL4 rceptor signaling in B lymphocytes |
| 0.1 | 3.1 | PID AVB3 INTEGRIN PATHWAY | Integrins in angiogenesis |
| 0.1 | 0.9 | PID INTEGRIN5 PATHWAY | Beta5 beta6 beta7 and beta8 integrin cell surface interactions |
| 0.1 | 3.7 | PID FAK PATHWAY | Signaling events mediated by focal adhesion kinase |
| 0.1 | 2.6 | PID FCER1 PATHWAY | Fc-epsilon receptor I signaling in mast cells |
| 0.1 | 0.3 | PID S1P S1P2 PATHWAY | S1P2 pathway |
| 0.1 | 2.1 | PID UPA UPAR PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
| 0.1 | 3.6 | NABA BASEMENT MEMBRANES | Genes encoding structural components of basement membranes |
| 0.1 | 5.8 | PID NOTCH PATHWAY | Notch signaling pathway |
| 0.0 | 2.0 | PID ARF6 PATHWAY | Arf6 signaling events |
| 0.0 | 1.9 | PID PI3KCI AKT PATHWAY | Class I PI3K signaling events mediated by Akt |
| 0.0 | 1.1 | PID NETRIN PATHWAY | Netrin-mediated signaling events |
| 0.0 | 4.7 | PID TELOMERASE PATHWAY | Regulation of Telomerase |
| 0.0 | 3.1 | ST INTEGRIN SIGNALING PATHWAY | Integrin Signaling Pathway |
| 0.0 | 2.5 | PID RAC1 PATHWAY | RAC1 signaling pathway |
| 0.0 | 3.4 | PID P53 REGULATION PATHWAY | p53 pathway |
| 0.0 | 2.5 | PID TGFBR PATHWAY | TGF-beta receptor signaling |
| 0.0 | 2.2 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
| 0.0 | 0.7 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
| 0.0 | 1.4 | PID ENDOTHELIN PATHWAY | Endothelins |
| 0.0 | 1.1 | PID CDC42 PATHWAY | CDC42 signaling events |
| 0.0 | 0.4 | PID SYNDECAN 4 PATHWAY | Syndecan-4-mediated signaling events |
| 0.0 | 0.2 | SIG BCR SIGNALING PATHWAY | Members of the BCR signaling pathway |
| 0.0 | 0.3 | SA CASPASE CASCADE | Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade. |
| 0.0 | 0.2 | PID ARF6 DOWNSTREAM PATHWAY | Arf6 downstream pathway |
| 0.0 | 1.8 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 5.5 | REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS | Genes involved in Apoptotic cleavage of cell adhesion proteins |
| 0.2 | 2.6 | REACTOME RAF MAP KINASE CASCADE | Genes involved in RAF/MAP kinase cascade |
| 0.2 | 2.5 | REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE | Genes involved in Reversible Hydration of Carbon Dioxide |
| 0.1 | 4.4 | REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION | Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) |
| 0.1 | 2.4 | REACTOME CD28 DEPENDENT VAV1 PATHWAY | Genes involved in CD28 dependent Vav1 pathway |
| 0.1 | 1.9 | REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL | Genes involved in NF-kB is activated and signals survival |
| 0.1 | 5.4 | REACTOME ENOS ACTIVATION AND REGULATION | Genes involved in eNOS activation and regulation |
| 0.1 | 1.7 | REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE | Genes involved in Regulation of Insulin Secretion by Acetylcholine |
| 0.1 | 2.1 | REACTOME RECYCLING OF BILE ACIDS AND SALTS | Genes involved in Recycling of bile acids and salts |
| 0.1 | 3.0 | REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
| 0.1 | 4.5 | REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS | Genes involved in Termination of O-glycan biosynthesis |
| 0.1 | 2.1 | REACTOME HYALURONAN UPTAKE AND DEGRADATION | Genes involved in Hyaluronan uptake and degradation |
| 0.1 | 4.7 | REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB | Genes involved in PKA-mediated phosphorylation of CREB |
| 0.1 | 1.3 | REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT | Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript |
| 0.1 | 6.4 | REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS | Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers |
| 0.1 | 1.9 | REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION | Genes involved in Apoptosis induced DNA fragmentation |
| 0.1 | 6.4 | REACTOME GLUCOSE TRANSPORT | Genes involved in Glucose transport |
| 0.1 | 1.9 | REACTOME NOTCH HLH TRANSCRIPTION PATHWAY | Genes involved in Notch-HLH transcription pathway |
| 0.1 | 1.3 | REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA | Genes involved in Activation of Chaperone Genes by ATF6-alpha |
| 0.1 | 2.8 | REACTOME SYNTHESIS OF PC | Genes involved in Synthesis of PC |
| 0.1 | 3.8 | REACTOME IL 2 SIGNALING | Genes involved in Interleukin-2 signaling |
| 0.1 | 3.2 | REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
| 0.1 | 1.2 | REACTOME PACKAGING OF TELOMERE ENDS | Genes involved in Packaging Of Telomere Ends |
| 0.1 | 3.8 | REACTOME ADHERENS JUNCTIONS INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.1 | 1.0 | REACTOME DIGESTION OF DIETARY CARBOHYDRATE | Genes involved in Digestion of dietary carbohydrate |
| 0.1 | 2.8 | REACTOME MRNA CAPPING | Genes involved in mRNA Capping |
| 0.1 | 5.1 | REACTOME AMYLOIDS | Genes involved in Amyloids |
| 0.1 | 2.6 | REACTOME DEADENYLATION OF MRNA | Genes involved in Deadenylation of mRNA |
| 0.0 | 1.3 | REACTOME BILE ACID AND BILE SALT METABOLISM | Genes involved in Bile acid and bile salt metabolism |
| 0.0 | 3.1 | REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM | Genes involved in Chondroitin sulfate/dermatan sulfate metabolism |
| 0.0 | 0.8 | REACTOME HDL MEDIATED LIPID TRANSPORT | Genes involved in HDL-mediated lipid transport |
| 0.0 | 1.8 | REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS | Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis |
| 0.0 | 2.5 | REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE | Genes involved in Nitric oxide stimulates guanylate cyclase |
| 0.0 | 4.4 | REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES | Genes involved in Loss of Nlp from mitotic centrosomes |
| 0.0 | 1.8 | REACTOME HS GAG BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
| 0.0 | 1.7 | REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS | Genes involved in CREB phosphorylation through the activation of Ras |
| 0.0 | 1.0 | REACTOME DCC MEDIATED ATTRACTIVE SIGNALING | Genes involved in DCC mediated attractive signaling |
| 0.0 | 2.5 | REACTOME STRIATED MUSCLE CONTRACTION | Genes involved in Striated Muscle Contraction |
| 0.0 | 0.6 | REACTOME ABACAVIR TRANSPORT AND METABOLISM | Genes involved in Abacavir transport and metabolism |
| 0.0 | 3.4 | REACTOME METABOLISM OF VITAMINS AND COFACTORS | Genes involved in Metabolism of vitamins and cofactors |
| 0.0 | 0.7 | REACTOME RECRUITMENT OF MITOTIC CENTROSOME PROTEINS AND COMPLEXES | Genes involved in Recruitment of mitotic centrosome proteins and complexes |
| 0.0 | 3.2 | REACTOME NRAGE SIGNALS DEATH THROUGH JNK | Genes involved in NRAGE signals death through JNK |
| 0.0 | 2.3 | REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES | Genes involved in Cross-presentation of soluble exogenous antigens (endosomes) |
| 0.0 | 4.6 | REACTOME MRNA SPLICING | Genes involved in mRNA Splicing |
| 0.0 | 0.4 | REACTOME PLATELET CALCIUM HOMEOSTASIS | Genes involved in Platelet calcium homeostasis |
| 0.0 | 1.1 | REACTOME CELL CELL JUNCTION ORGANIZATION | Genes involved in Cell-cell junction organization |
| 0.0 | 1.3 | REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
| 0.0 | 1.1 | REACTOME NETRIN1 SIGNALING | Genes involved in Netrin-1 signaling |
| 0.0 | 0.5 | REACTOME METABOLISM OF NON CODING RNA | Genes involved in Metabolism of non-coding RNA |
| 0.0 | 0.2 | REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 | Genes involved in IKK complex recruitment mediated by RIP1 |
| 0.0 | 0.2 | REACTOME PROLONGED ERK ACTIVATION EVENTS | Genes involved in Prolonged ERK activation events |
| 0.0 | 0.4 | REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX | Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex |
| 0.0 | 0.7 | REACTOME EFFECTS OF PIP2 HYDROLYSIS | Genes involved in Effects of PIP2 hydrolysis |
| 0.0 | 0.5 | REACTOME ACTIVATION OF NF KAPPAB IN B CELLS | Genes involved in Activation of NF-kappaB in B Cells |
| 0.0 | 0.2 | REACTOME GAB1 SIGNALOSOME | Genes involved in GAB1 signalosome |
| 0.0 | 0.5 | REACTOME BASIGIN INTERACTIONS | Genes involved in Basigin interactions |
| 0.0 | 1.3 | REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | Genes involved in NOTCH1 Intracellular Domain Regulates Transcription |
| 0.0 | 1.2 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |
| 0.0 | 0.4 | REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC | Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC |
| 0.0 | 0.2 | REACTOME THE NLRP3 INFLAMMASOME | Genes involved in The NLRP3 inflammasome |
| 0.0 | 0.4 | REACTOME G1 S SPECIFIC TRANSCRIPTION | Genes involved in G1/S-Specific Transcription |
| 0.0 | 1.4 | REACTOME SIGNALING BY PDGF | Genes involved in Signaling by PDGF |
| 0.0 | 0.7 | REACTOME MEIOTIC SYNAPSIS | Genes involved in Meiotic Synapsis |
| 0.0 | 0.2 | REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION | Genes involved in Mitochondrial Fatty Acid Beta-Oxidation |
| 0.0 | 1.1 | REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS | Genes involved in Golgi Associated Vesicle Biogenesis |
| 0.0 | 0.3 | REACTOME METABOLISM OF PORPHYRINS | Genes involved in Metabolism of porphyrins |