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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for TP53

Z-value: 0.58

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Transcription factors associated with TP53

Gene Symbol Gene ID Gene Info
ENSG00000141510.11 tumor protein p53

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TP53hg19_v2_chr17_-_7590745_7590856-0.361.1e-01Click!

Activity profile of TP53 motif

Sorted Z-values of TP53 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_153588334 3.05 ENST00000476873.1
S100 calcium binding protein A14
chr19_+_3136115 2.45 ENST00000262958.3
guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
chr6_+_36098262 2.24 ENST00000373761.6
ENST00000373766.5
mitogen-activated protein kinase 13
chr8_-_10588010 2.02 ENST00000304501.1
SRY (sex determining region Y)-box 7
chr18_-_28622699 1.95 ENST00000360428.4
desmocollin 3
chr3_-_12800751 1.94 ENST00000435218.2
ENST00000435575.1
transmembrane protein 40
chr18_-_28622774 1.93 ENST00000434452.1
desmocollin 3
chr1_-_209825674 1.60 ENST00000367030.3
ENST00000356082.4
laminin, beta 3
chr1_+_13910194 1.58 ENST00000376057.4
ENST00000510906.1
podoplanin
chr10_+_48255253 1.41 ENST00000357718.4
ENST00000344416.5
ENST00000456111.2
ENST00000374258.3
annexin A8
Protein LOC100996760
chr2_+_208104497 1.40 ENST00000430494.1
AC007879.7
chr1_+_13910757 1.38 ENST00000376061.4
ENST00000513143.1
podoplanin
chr1_-_26197744 1.38 ENST00000374296.3
progestin and adipoQ receptor family member VII
chr10_-_47173994 1.34 ENST00000414655.2
ENST00000545298.1
ENST00000359178.4
ENST00000358140.4
ENST00000503031.1
annexin A8-like 1
long intergenic non-protein coding RNA 842
chrX_+_99899180 1.34 ENST00000373004.3
sushi-repeat containing protein, X-linked 2
chr1_+_13910479 1.11 ENST00000509009.1
podoplanin
chr10_+_47746929 1.11 ENST00000340243.6
ENST00000374277.5
ENST00000449464.2
ENST00000538825.1
ENST00000335083.5
annexin A8-like 2
Protein LOC100996760
chr5_-_95297534 1.06 ENST00000513343.1
ENST00000431061.2
elongation factor, RNA polymerase II, 2
chr6_+_36097992 1.05 ENST00000211287.4
mitogen-activated protein kinase 13
chr11_+_5712234 1.05 ENST00000414641.1
tripartite motif containing 22
chr22_+_38302285 1.04 ENST00000215957.6
MICAL-like 1
chr9_-_95527079 1.00 ENST00000356884.6
ENST00000375512.3
bicaudal D homolog 2 (Drosophila)
chr19_+_39687596 0.98 ENST00000339852.4
non-specific cytotoxic cell receptor protein 1 homolog (zebrafish)
chr9_+_132094579 0.95 ENST00000427109.1
RP11-65J3.1
chr4_-_10117949 0.94 ENST00000508079.1
WD repeat domain 1
chr8_+_22960426 0.90 ENST00000540813.1
tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
chrX_+_152086373 0.89 ENST00000318529.8
zinc finger protein 185 (LIM domain)
chr1_-_10532531 0.88 ENST00000377036.2
ENST00000377038.3
DNA fragmentation factor, 45kDa, alpha polypeptide
chr1_-_1356719 0.88 ENST00000520296.1
ankyrin repeat domain 65
chr14_-_36990354 0.85 ENST00000518149.1
NK2 homeobox 1
chr6_+_36098363 0.81 ENST00000373759.1
mitogen-activated protein kinase 13
chr4_+_186347388 0.79 ENST00000511138.1
ENST00000511581.1
chromosome 4 open reading frame 47
chr4_-_187644930 0.75 ENST00000441802.2
FAT atypical cadherin 1
chr1_+_116519112 0.75 ENST00000369503.4
solute carrier family 22, member 15
chr1_-_1356628 0.74 ENST00000442470.1
ENST00000537107.1
ankyrin repeat domain 65
chr19_-_51530916 0.72 ENST00000594768.1
kallikrein-related peptidase 11
chr13_+_38923959 0.72 ENST00000379649.1
ENST00000239878.4
ENST00000437952.1
ENST00000379641.1
ubiquitin-fold modifier 1
chr1_-_202936394 0.72 ENST00000367249.4
cytochrome b5 reductase 1
chr3_+_184279566 0.71 ENST00000330394.2
EPH receptor B3
chr3_-_149510553 0.69 ENST00000462519.2
ENST00000446160.1
ENST00000383050.3
ankyrin repeat and ubiquitin domain containing 1
chr1_+_54519242 0.68 ENST00000234827.1
transcription elongation factor A (SII) N-terminal and central domain containing 2
chr12_-_53207842 0.68 ENST00000458244.2
keratin 4
chr6_-_138428613 0.68 ENST00000421351.3
PERP, TP53 apoptosis effector
chr19_-_14048804 0.68 ENST00000254320.3
ENST00000586075.1
podocan-like 1
chr1_-_156051789 0.68 ENST00000532414.2
mex-3 RNA binding family member A
chr17_+_74372662 0.66 ENST00000591651.1
ENST00000545180.1
sphingosine kinase 1
chr19_-_6481776 0.66 ENST00000543576.1
ENST00000590173.1
ENST00000381480.2
DENN/MADD domain containing 1C
chr16_+_57653625 0.64 ENST00000567553.1
ENST00000565314.1
G protein-coupled receptor 56
chr11_-_2160611 0.64 ENST00000416167.2
insulin-like growth factor 2 (somatomedin A)
chr3_-_46037299 0.64 ENST00000296137.2
FYVE and coiled-coil domain containing 1
chr1_+_24969755 0.62 ENST00000447431.2
ENST00000374389.4
serine/arginine repetitive matrix 1
chr1_-_154941350 0.62 ENST00000444179.1
ENST00000414115.1
SHC (Src homology 2 domain containing) transforming protein 1
chr11_-_59383617 0.62 ENST00000263847.1
oxysterol binding protein
chr6_+_116692102 0.59 ENST00000359564.2
dermatan sulfate epimerase
chr12_+_69202795 0.58 ENST00000539479.1
ENST00000393415.3
ENST00000523991.1
ENST00000543323.1
ENST00000393416.2
MDM2 oncogene, E3 ubiquitin protein ligase
chr14_-_75079026 0.58 ENST00000261978.4
latent transforming growth factor beta binding protein 2
chr9_-_135996537 0.58 ENST00000372050.3
ENST00000372047.3
ral guanine nucleotide dissociation stimulator
chr1_+_117910047 0.57 ENST00000356554.3
mannosidase, alpha, class 1A, member 2
chr8_-_29592736 0.57 ENST00000518623.1
long intergenic non-protein coding RNA 589
chr8_-_23082580 0.55 ENST00000221132.3
tumor necrosis factor receptor superfamily, member 10a
chr14_-_36990061 0.55 ENST00000546983.1
NK2 homeobox 1
chr19_-_5567996 0.55 ENST00000448587.1
tissue differentiation-inducing non-protein coding RNA
chr6_-_101329191 0.54 ENST00000324723.6
ENST00000369162.2
ENST00000522650.1
activating signal cointegrator 1 complex subunit 3
chr6_-_114292449 0.52 ENST00000519065.1
histone deacetylase 2
chr6_+_76458990 0.51 ENST00000369977.3
myosin VI
chrX_+_3189861 0.50 ENST00000457435.1
ENST00000420429.2
chromosome X open reading frame 28
chr16_-_15149828 0.50 ENST00000566419.1
ENST00000568320.1
N-terminal asparagine amidase
chr6_-_114292284 0.50 ENST00000520895.1
ENST00000521163.1
ENST00000524334.1
ENST00000368632.2
ENST00000398283.2
histone deacetylase 2
chr2_+_95691445 0.49 ENST00000353004.3
ENST00000354078.3
ENST00000349807.3
mal, T-cell differentiation protein
chr15_+_40532058 0.48 ENST00000260404.4
p21 protein (Cdc42/Rac)-activated kinase 6
chr15_+_79165222 0.48 ENST00000559930.1
mortality factor 4 like 1
chr6_-_109804412 0.47 ENST00000230122.3
zinc finger and BTB domain containing 24
chr5_+_178487354 0.46 ENST00000315475.6
zinc finger protein 354C
chr19_+_28284803 0.46 ENST00000586220.1
ENST00000588784.1
ENST00000591549.1
ENST00000585827.1
ENST00000588636.1
ENST00000587188.1
CTC-459F4.3
chr11_-_129062093 0.46 ENST00000310343.9
Rho GTPase activating protein 32
chr16_+_57653989 0.46 ENST00000567835.1
ENST00000569372.1
ENST00000563548.1
ENST00000562003.1
G protein-coupled receptor 56
chr4_-_10118348 0.45 ENST00000502702.1
WD repeat domain 1
chr10_-_73611046 0.44 ENST00000394934.1
ENST00000394936.3
prosaposin
chr9_+_130186653 0.44 ENST00000342483.5
ENST00000543471.1
zinc finger protein 79
chr16_-_15149917 0.43 ENST00000287706.3
N-terminal asparagine amidase
chr11_+_33279850 0.43 ENST00000531504.1
ENST00000456517.1
homeodomain interacting protein kinase 3
chr1_-_54519067 0.43 ENST00000452421.1
ENST00000420738.1
ENST00000234831.5
ENST00000440019.1
transmembrane protein 59
chr11_-_73309112 0.42 ENST00000450446.2
family with sequence similarity 168, member A
chr12_-_113772835 0.42 ENST00000552014.1
ENST00000548186.1
ENST00000202831.3
ENST00000549181.1
solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
chr14_-_75078725 0.42 ENST00000556690.1
latent transforming growth factor beta binding protein 2
chr17_-_61523622 0.41 ENST00000448884.2
ENST00000582297.1
ENST00000582034.1
ENST00000578072.1
ENST00000360793.3
cytochrome b561
chr16_-_75467318 0.41 ENST00000283882.3
craniofacial development protein 1
chr4_+_71768043 0.41 ENST00000502869.1
ENST00000309395.2
ENST00000396051.2
MOB kinase activator 1B
chr1_+_44115814 0.41 ENST00000372396.3
lysine (K)-specific demethylase 4A
chr1_-_113249734 0.40 ENST00000484054.3
ENST00000369636.2
ENST00000369637.1
ENST00000285735.2
ENST00000369638.2
ras homolog family member C
chr1_-_113249678 0.40 ENST00000369633.2
ENST00000425265.2
ENST00000369632.2
ENST00000436685.2
ras homolog family member C
chr17_+_14204389 0.39 ENST00000360954.2
heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
chr11_+_1855645 0.39 ENST00000381968.3
ENST00000381978.3
synaptotagmin VIII
chr20_+_57467204 0.38 ENST00000603546.1
GNAS complex locus
chr10_+_90750493 0.38 ENST00000357339.2
ENST00000355279.2
Fas cell surface death receptor
chr16_-_75467274 0.38 ENST00000566254.1
craniofacial development protein 1
chr4_+_6784401 0.37 ENST00000425103.1
ENST00000307659.5
KIAA0232
chr4_-_48908737 0.37 ENST00000381464.2
OCIA domain containing 2
chr1_+_116519223 0.37 ENST00000369502.1
solute carrier family 22, member 15
chr14_+_36295638 0.37 ENST00000543183.1
breast cancer metastasis-suppressor 1-like
chr12_+_44229846 0.37 ENST00000551577.1
ENST00000266534.3
transmembrane protein 117
chrX_-_106959631 0.37 ENST00000486554.1
ENST00000372390.4
TSC22 domain family, member 3
chr17_-_7387524 0.37 ENST00000311403.4
zinc finger and BTB domain containing 4
chr1_-_205744574 0.36 ENST00000367139.3
ENST00000235932.4
ENST00000437324.2
ENST00000414729.1
RAB7, member RAS oncogene family-like 1
chr3_+_196466710 0.36 ENST00000327134.3
p21 protein (Cdc42/Rac)-activated kinase 2
chr1_-_54519134 0.35 ENST00000371341.1
transmembrane protein 59
chr19_-_14228541 0.35 ENST00000590853.1
ENST00000308677.4
protein kinase, cAMP-dependent, catalytic, alpha
chr3_+_49977440 0.34 ENST00000442092.1
ENST00000266022.4
ENST00000443081.1
RNA binding motif protein 6
chr4_-_48908822 0.34 ENST00000508632.1
OCIA domain containing 2
chr12_+_69202975 0.34 ENST00000544561.1
ENST00000393410.1
ENST00000299252.4
ENST00000360430.2
ENST00000517852.1
ENST00000545204.1
ENST00000393413.3
ENST00000350057.5
ENST00000348801.2
ENST00000478070.1
MDM2 oncogene, E3 ubiquitin protein ligase
chr16_+_57653854 0.34 ENST00000568908.1
ENST00000568909.1
ENST00000566778.1
ENST00000561988.1
G protein-coupled receptor 56
chr7_+_116165754 0.33 ENST00000405348.1
caveolin 1, caveolae protein, 22kDa
chr6_+_4776580 0.33 ENST00000397588.3
chromodomain protein, Y-like
chr3_-_52001448 0.33 ENST00000461554.1
ENST00000395013.3
ENST00000428823.2
ENST00000483411.1
ENST00000461544.1
ENST00000355852.2
poly(rC) binding protein 4
chr3_+_44379944 0.33 ENST00000396078.3
ENST00000342649.4
T cell activation inhibitor, mitochondrial
chr1_+_43148625 0.33 ENST00000436427.1
Y box binding protein 1
chr20_-_1373682 0.33 ENST00000381724.3
FK506 binding protein 1A, 12kDa
chr4_-_186347099 0.32 ENST00000505357.1
ENST00000264689.6
UFM1-specific peptidase 2
chr22_+_42949925 0.32 ENST00000327678.5
ENST00000340239.4
ENST00000407614.4
ENST00000335879.5
serine hydrolase-like 2
chr11_-_77122928 0.32 ENST00000528203.1
ENST00000528592.1
ENST00000528633.1
ENST00000529248.1
p21 protein (Cdc42/Rac)-activated kinase 1
chr19_+_13229126 0.32 ENST00000292431.4
nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
chr2_+_95691417 0.31 ENST00000309988.4
mal, T-cell differentiation protein
chr4_-_159644507 0.31 ENST00000307720.3
peptidylprolyl isomerase D
chr10_+_134000404 0.30 ENST00000338492.4
ENST00000368629.1
dihydropyrimidinase-like 4
chr1_-_155532484 0.30 ENST00000368346.3
ENST00000548830.1
ash1 (absent, small, or homeotic)-like (Drosophila)
chr4_-_10118573 0.30 ENST00000382452.2
ENST00000382451.2
WD repeat domain 1
chr22_+_21336267 0.30 ENST00000215739.8
leucine-zipper-like transcription regulator 1
chr7_-_99766191 0.30 ENST00000423751.1
ENST00000360039.4
galactose-3-O-sulfotransferase 4
chr1_-_205744205 0.30 ENST00000446390.2
RAB7, member RAS oncogene family-like 1
chr11_+_1856034 0.30 ENST00000341958.3
synaptotagmin VIII
chr13_+_37006421 0.30 ENST00000255465.4
cyclin A1
chr19_-_44258733 0.29 ENST00000597586.1
ENST00000596714.1
SMG9 nonsense mediated mRNA decay factor
chr7_+_75024903 0.29 ENST00000323819.3
ENST00000430211.1
tripartite motif containing 73
chr19_-_44258770 0.29 ENST00000601925.1
ENST00000602222.1
ENST00000599804.1
SMG9 nonsense mediated mRNA decay factor
chr1_-_2458026 0.29 ENST00000435556.3
ENST00000378466.3
pantothenate kinase 4
chr8_-_23021533 0.28 ENST00000312584.3
tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
chr17_+_25621102 0.28 ENST00000581440.1
ENST00000262394.2
ENST00000583742.1
ENST00000579733.1
ENST00000583193.1
ENST00000581185.1
ENST00000427287.2
ENST00000348811.2
WD repeat and SOCS box containing 1
chr4_-_10118469 0.28 ENST00000499869.2
WD repeat domain 1
chr3_-_113464906 0.28 ENST00000477813.1
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr18_+_34409069 0.28 ENST00000543923.1
ENST00000280020.5
ENST00000435985.2
ENST00000592521.1
ENST00000587139.1
KIAA1328
chr13_+_76334498 0.27 ENST00000534657.1
LIM domain 7
chr7_+_100770328 0.27 ENST00000223095.4
ENST00000445463.2
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
chr12_-_126467906 0.27 ENST00000507313.1
ENST00000545784.1
long intergenic non-protein coding RNA 939
chr9_-_140115775 0.27 ENST00000391553.1
ENST00000392827.1
ring finger protein 208
chr8_-_22926623 0.27 ENST00000276431.4
tumor necrosis factor receptor superfamily, member 10b
chr21_+_44313375 0.27 ENST00000354250.2
ENST00000340344.4
NADH dehydrogenase (ubiquinone) flavoprotein 3, 10kDa
chr1_+_25599018 0.26 ENST00000417538.2
ENST00000357542.4
ENST00000568195.1
ENST00000342055.5
ENST00000423810.2
Rh blood group, D antigen
chr19_+_57874835 0.26 ENST00000543226.1
ENST00000596755.1
ENST00000282282.3
ENST00000597658.1
trafficking protein particle complex 2 pseudogene 1
zinc finger protein 547
Uncharacterized protein
chr16_+_15744078 0.26 ENST00000396354.1
ENST00000570727.1
nudE neurodevelopment protein 1
chr8_+_22429205 0.26 ENST00000520207.1
sorbin and SH3 domain containing 3
chr11_-_3078838 0.26 ENST00000397111.5
cysteinyl-tRNA synthetase
chr10_+_124134201 0.25 ENST00000368990.3
ENST00000368988.1
ENST00000368989.2
ENST00000463663.2
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr17_-_74528128 0.25 ENST00000590175.1
cytoglobin
chr9_-_115774453 0.25 ENST00000427548.1
zinc finger protein 883
chr18_-_34408902 0.25 ENST00000593035.1
ENST00000383056.3
ENST00000588909.1
ENST00000590337.1
tubulin polyglutamylase complex subunit 2
chr12_-_59314246 0.25 ENST00000320743.3
leucine-rich repeats and immunoglobulin-like domains 3
chr10_-_90751038 0.24 ENST00000458159.1
ENST00000415557.1
ENST00000458208.1
actin, alpha 2, smooth muscle, aorta
chr18_-_34409116 0.24 ENST00000334295.4
tubulin polyglutamylase complex subunit 2
chr10_-_71993138 0.24 ENST00000608321.1
pyrophosphatase (inorganic) 1
chr14_-_50999190 0.24 ENST00000557390.1
mitogen-activated protein kinase kinase kinase kinase 5
chr20_+_57466629 0.24 ENST00000371081.1
ENST00000338783.6
GNAS complex locus
chr16_-_67997947 0.24 ENST00000537830.2
solute carrier family 12 (potassium/chloride transporter), member 4
chr11_-_3078616 0.23 ENST00000401769.3
ENST00000278224.9
ENST00000397114.3
ENST00000380525.4
cysteinyl-tRNA synthetase
chr4_+_103422499 0.23 ENST00000511926.1
ENST00000507079.1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr13_+_37006398 0.22 ENST00000418263.1
cyclin A1
chr22_+_40766582 0.22 ENST00000457767.1
ENST00000248929.9
ENST00000454798.2
small G protein signaling modulator 3
chr6_-_30712313 0.22 ENST00000376377.2
ENST00000259874.5
immediate early response 3
chr16_-_70713928 0.22 ENST00000576338.1
metastasis suppressor 1-like
chr3_+_127771212 0.21 ENST00000243253.3
ENST00000481210.1
Sec61 alpha 1 subunit (S. cerevisiae)
chr3_+_49977490 0.21 ENST00000539992.1
RNA binding motif protein 6
chr17_-_61523535 0.21 ENST00000584031.1
ENST00000392976.1
cytochrome b561
chr22_-_36925124 0.21 ENST00000457241.1
eukaryotic translation initiation factor 3, subunit D
chr2_-_242447983 0.21 ENST00000426941.1
ENST00000405585.1
ENST00000420551.1
ENST00000535007.1
ENST00000429279.1
ENST00000442307.1
ENST00000403346.3
ENST00000316586.4
serine/threonine kinase 25
chr3_+_49977523 0.20 ENST00000422955.1
RNA binding motif protein 6
chr20_+_43595115 0.20 ENST00000372806.3
ENST00000396731.4
ENST00000372801.1
ENST00000499879.2
serine/threonine kinase 4
chr9_+_116037922 0.20 ENST00000374198.4
pre-mRNA processing factor 4
chr2_-_176033066 0.20 ENST00000437522.1
activating transcription factor 2
chr1_-_243418621 0.20 ENST00000366544.1
ENST00000366543.1
centrosomal protein 170kDa
chr19_+_13228917 0.19 ENST00000586171.1
nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
chr6_+_24403144 0.19 ENST00000274747.7
ENST00000543597.1
ENST00000535061.1
ENST00000378353.1
ENST00000378386.3
ENST00000443868.2
MRS2 magnesium transporter
chr4_-_48908805 0.19 ENST00000273860.4
OCIA domain containing 2
chr19_-_5567842 0.19 ENST00000587632.1
tissue differentiation-inducing non-protein coding RNA
chr11_+_706595 0.19 ENST00000531348.1
ENST00000530636.1
EPS8-like 2
chr2_-_37193606 0.19 ENST00000379213.2
ENST00000263918.4
striatin, calmodulin binding protein
chr15_+_41913690 0.18 ENST00000563576.1
MGA, MAX dimerization protein
chr6_+_33378517 0.18 ENST00000428274.1
PHD finger protein 1
chr5_+_141348755 0.18 ENST00000506004.1
ENST00000507291.1
ring finger protein 14
chr1_-_169396646 0.18 ENST00000367806.3
coiled-coil domain containing 181
chr4_-_129209221 0.18 ENST00000512483.1
progesterone receptor membrane component 2
chr7_+_63361201 0.18 ENST00000450544.1
RP11-340I6.8
chr11_-_77123065 0.18 ENST00000530617.1
p21 protein (Cdc42/Rac)-activated kinase 1
chr22_+_19705928 0.17 ENST00000383045.3
ENST00000438754.2
septin 5
chr20_-_1373606 0.17 ENST00000381715.1
ENST00000439640.2
ENST00000381719.3
FK506 binding protein 1A, 12kDa
chr1_+_114447763 0.17 ENST00000369563.3
DNA cross-link repair 1B
chr4_-_153457197 0.17 ENST00000281708.4
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr11_-_108464321 0.17 ENST00000265843.4
exophilin 5
chr20_-_61002584 0.17 ENST00000252998.1
RBBP8 N-terminal like
chr3_+_44379611 0.17 ENST00000383746.3
ENST00000417237.1
T cell activation inhibitor, mitochondrial
chr2_-_75788428 0.17 ENST00000432649.1
eva-1 homolog A (C. elegans)
chr16_-_58231782 0.17 ENST00000565188.1
ENST00000262506.3
casein kinase 2, alpha prime polypeptide

Network of associatons between targets according to the STRING database.

First level regulatory network of TP53

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.1 GO:1904328 regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)
0.5 2.0 GO:0042247 morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247)
0.4 1.4 GO:1900138 negative regulation of phospholipase A2 activity(GO:1900138)
0.3 0.9 GO:0071301 cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.3 2.5 GO:0007207 phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.3 0.9 GO:1903625 negative regulation of DNA catabolic process(GO:1903625)
0.2 0.7 GO:0046521 sphingoid catabolic process(GO:0046521)
0.2 0.9 GO:0090285 negative regulation of protein glycosylation in Golgi(GO:0090285)
0.2 0.5 GO:0006423 cysteinyl-tRNA aminoacylation(GO:0006423)
0.2 0.5 GO:1905053 regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053)
0.1 1.0 GO:0006344 maintenance of chromatin silencing(GO:0006344)
0.1 1.0 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.1 0.8 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.1 3.3 GO:0090026 positive regulation of monocyte chemotaxis(GO:0090026)
0.1 1.4 GO:0021759 globus pallidus development(GO:0021759)
0.1 0.3 GO:1900085 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
0.1 0.7 GO:1990592 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.1 0.3 GO:0045083 negative regulation of interleukin-12 biosynthetic process(GO:0045083)
0.1 0.6 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.1 0.6 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.1 0.6 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.1 0.8 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.1 0.4 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 1.3 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.1 0.8 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1 0.4 GO:2001270 regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 0.2 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.1 0.6 GO:0044126 regulation of growth of symbiont in host(GO:0044126)
0.1 0.4 GO:0097527 necroptotic signaling pathway(GO:0097527)
0.1 0.5 GO:0061052 negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
0.1 0.3 GO:0097676 histone H3-K36 dimethylation(GO:0097676)
0.0 0.2 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 0.6 GO:0022417 protein maturation by protein folding(GO:0022417)
0.0 0.5 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.0 0.4 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.6 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.0 0.1 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922) negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.0 1.6 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.4 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 0.3 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.0 0.2 GO:0090131 mesenchyme migration(GO:0090131)
0.0 0.2 GO:0071344 diphosphate metabolic process(GO:0071344)
0.0 0.3 GO:2000490 negative regulation of hepatic stellate cell activation(GO:2000490)
0.0 0.2 GO:0039019 pronephric nephron development(GO:0039019)
0.0 0.7 GO:0002934 desmosome organization(GO:0002934)
0.0 0.2 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.0 0.1 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
0.0 0.2 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 0.4 GO:0036481 intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036481)
0.0 1.1 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 0.5 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 0.1 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.0 0.3 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.1 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.4 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.0 4.0 GO:0032755 positive regulation of interleukin-6 production(GO:0032755)
0.0 0.3 GO:0071492 cellular response to UV-A(GO:0071492)
0.0 0.1 GO:0046168 glycerol-3-phosphate catabolic process(GO:0046168)
0.0 0.4 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 4.6 GO:0070268 cornification(GO:0070268)
0.0 0.2 GO:0031860 telomeric loop formation(GO:0031627) telomeric 3' overhang formation(GO:0031860)
0.0 0.1 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0 0.2 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.1 GO:0043335 protein unfolding(GO:0043335)
0.0 2.0 GO:0001706 endoderm formation(GO:0001706)
0.0 0.4 GO:0060742 epithelial cell differentiation involved in prostate gland development(GO:0060742)
0.0 0.2 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.0 0.6 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.9 GO:0097435 fibril organization(GO:0097435)
0.0 0.1 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.4 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.0 0.7 GO:0022038 corpus callosum development(GO:0022038)
0.0 0.4 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.1 GO:0070458 establishment of blood-nerve barrier(GO:0008065) cellular detoxification of nitrogen compound(GO:0070458)
0.0 0.1 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0 0.2 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 0.1 GO:0001302 replicative cell aging(GO:0001302)
0.0 0.3 GO:0001553 luteinization(GO:0001553)
0.0 1.0 GO:0008284 positive regulation of cell proliferation(GO:0008284)
0.0 0.1 GO:0008218 bioluminescence(GO:0008218)
0.0 0.5 GO:0015695 organic cation transport(GO:0015695)
0.0 0.6 GO:0007176 regulation of epidermal growth factor-activated receptor activity(GO:0007176)
0.0 0.3 GO:2000574 regulation of microtubule motor activity(GO:2000574)
0.0 0.5 GO:0007141 male meiosis I(GO:0007141)
0.0 0.1 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.0 0.7 GO:0007340 acrosome reaction(GO:0007340)
0.0 0.3 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.1 GO:0038033 positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway(GO:0038033)
0.0 0.3 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.1 GO:2000234 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 1.5 GO:0048477 oogenesis(GO:0048477)
0.0 1.0 GO:0070206 protein trimerization(GO:0070206)
0.0 0.1 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.7 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.2 GO:0051865 protein autoubiquitination(GO:0051865)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.0 GO:0042643 actomyosin, actin portion(GO:0042643)
0.3 4.1 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 1.6 GO:0005610 laminin-5 complex(GO:0005610)
0.1 0.6 GO:1990425 ryanodine receptor complex(GO:1990425)
0.1 0.9 GO:0005797 Golgi medial cisterna(GO:0005797)
0.1 0.5 GO:0097123 cyclin A1-CDK2 complex(GO:0097123)
0.1 4.6 GO:0030057 desmosome(GO:0030057)
0.1 0.6 GO:0070435 Shc-EGFR complex(GO:0070435)
0.1 1.0 GO:0005642 annulate lamellae(GO:0005642)
0.1 0.4 GO:0031415 NatA complex(GO:0031415)
0.1 0.2 GO:0071001 U4/U6 snRNP(GO:0071001)
0.0 3.1 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.1 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.2 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.3 GO:0002177 manchette(GO:0002177)
0.0 1.4 GO:0070822 Sin3-type complex(GO:0070822)
0.0 0.3 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 0.4 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.6 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.2 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.2 GO:1902560 GMP reductase complex(GO:1902560)
0.0 0.2 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.3 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.1 GO:1990769 proximal neuron projection(GO:1990769)
0.0 0.3 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.1 GO:0043293 apoptosome(GO:0043293)
0.0 0.4 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.7 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.1 GO:0071203 WASH complex(GO:0071203)
0.0 1.1 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.1 GO:0072589 box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.0 0.4 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.5 GO:0071437 invadopodium(GO:0071437)
0.0 0.1 GO:1990393 3M complex(GO:1990393)
0.0 0.3 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.8 GO:0015030 Cajal body(GO:0015030)
0.0 1.0 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.1 GO:0035686 sperm fibrous sheath(GO:0035686)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.1 GO:0045569 TRAIL binding(GO:0045569)
0.3 0.9 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.3 4.1 GO:0008517 folic acid transporter activity(GO:0008517)
0.2 0.5 GO:0060001 minus-end directed microfilament motor activity(GO:0060001)
0.2 0.5 GO:0004817 cysteine-tRNA ligase activity(GO:0004817)
0.2 0.6 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
0.1 0.6 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.1 4.0 GO:0004707 MAP kinase activity(GO:0004707)
0.1 0.3 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.1 0.7 GO:0008481 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.1 0.3 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.1 3.1 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.1 0.6 GO:0048408 epidermal growth factor binding(GO:0048408)
0.1 1.4 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.1 0.4 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 0.3 GO:0047888 fatty acid peroxidase activity(GO:0047888)
0.1 1.0 GO:0034452 dynactin binding(GO:0034452)
0.1 0.6 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.1 0.2 GO:0098808 mRNA cap binding(GO:0098808)
0.1 0.6 GO:0008142 oxysterol binding(GO:0008142)
0.1 0.5 GO:0043426 MRF binding(GO:0043426)
0.0 2.9 GO:0042379 chemokine receptor binding(GO:0042379)
0.0 0.7 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.8 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.4 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.6 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.6 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.4 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.1 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.0 0.2 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 1.5 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.2 GO:0042835 BRE binding(GO:0042835)
0.0 0.1 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0 3.5 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 1.0 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 1.0 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 0.4 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.6 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.7 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.1 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.0 0.2 GO:0030621 U4 snRNA binding(GO:0030621)
0.0 0.3 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.2 GO:0003920 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.0 0.2 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.3 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.4 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.4 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.3 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.8 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.1 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0 0.4 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.4 GO:0031005 filamin binding(GO:0031005)
0.0 0.2 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.5 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.0 0.1 GO:0004111 creatine kinase activity(GO:0004111)
0.0 1.3 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.1 GO:0030911 TPR domain binding(GO:0030911)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.1 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 2.2 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.1 1.6 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.9 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 1.3 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 2.1 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.5 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 0.6 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.7 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 1.0 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.8 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.5 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 1.5 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.5 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.7 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.9 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 0.7 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 2.7 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.5 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.2 4.5 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.1 1.1 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.9 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 1.0 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.8 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.7 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.6 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.1 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 0.6 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.6 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 1.3 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.6 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.4 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.7 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.5 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.7 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.6 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0 0.6 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 1.3 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.5 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.4 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.6 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing