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SARS-CoV-2 Analysis Results (GEO series: GSE147507)
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Results for TP63
Z-value: 4.12
Motif logo
Transcription factors associated with TP63
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
TP63
|
ENSG00000073282.8 | tumor protein p63 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| TP63 | hg19_v2_chr3_+_189507460_189507471 | 0.99 | 3.0e-19 | Click! |
Activity profile of TP63 motif
Sorted Z-values of TP63 motif
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr12_-_52887034 | 33.95 |
ENST00000330722.6
|
KRT6A
|
keratin 6A |
| chr15_+_101417919 | 32.36 |
ENST00000561338.1
|
ALDH1A3
|
aldehyde dehydrogenase 1 family, member A3 |
| chr12_-_15114603 | 31.19 |
ENST00000228945.4
|
ARHGDIB
|
Rho GDP dissociation inhibitor (GDI) beta |
| chr1_-_153588334 | 27.55 |
ENST00000476873.1
|
S100A14
|
S100 calcium binding protein A14 |
| chr3_+_122044084 | 25.18 |
ENST00000264474.3
ENST00000479204.1 |
CSTA
|
cystatin A (stefin A) |
| chr18_+_61143994 | 24.91 |
ENST00000382771.4
|
SERPINB5
|
serpin peptidase inhibitor, clade B (ovalbumin), member 5 |
| chr1_+_86889769 | 23.95 |
ENST00000370565.4
|
CLCA2
|
chloride channel accessory 2 |
| chr2_+_208104497 | 23.50 |
ENST00000430494.1
|
AC007879.7
|
AC007879.7 |
| chr12_-_15114492 | 22.18 |
ENST00000541546.1
|
ARHGDIB
|
Rho GDP dissociation inhibitor (GDI) beta |
| chr1_-_26197744 | 21.61 |
ENST00000374296.3
|
PAQR7
|
progestin and adipoQ receptor family member VII |
| chr12_-_52845910 | 20.40 |
ENST00000252252.3
|
KRT6B
|
keratin 6B |
| chr12_-_15114658 | 20.32 |
ENST00000542276.1
|
ARHGDIB
|
Rho GDP dissociation inhibitor (GDI) beta |
| chr18_+_61144160 | 19.52 |
ENST00000489441.1
ENST00000424602.1 |
SERPINB5
|
serpin peptidase inhibitor, clade B (ovalbumin), member 5 |
| chr11_+_18287801 | 18.21 |
ENST00000532858.1
ENST00000405158.2 |
SAA1
|
serum amyloid A1 |
| chr3_+_136676707 | 16.85 |
ENST00000329582.4
|
IL20RB
|
interleukin 20 receptor beta |
| chr11_+_18287721 | 16.32 |
ENST00000356524.4
|
SAA1
|
serum amyloid A1 |
| chr3_+_136676851 | 16.16 |
ENST00000309741.5
|
IL20RB
|
interleukin 20 receptor beta |
| chr15_+_41136216 | 16.03 |
ENST00000562057.1
ENST00000344051.4 |
SPINT1
|
serine peptidase inhibitor, Kunitz type 1 |
| chrX_+_2670066 | 15.88 |
ENST00000381174.5
ENST00000419513.2 ENST00000426774.1 |
XG
|
Xg blood group |
| chr4_-_10023095 | 14.69 |
ENST00000264784.3
|
SLC2A9
|
solute carrier family 2 (facilitated glucose transporter), member 9 |
| chr11_+_5712234 | 14.50 |
ENST00000414641.1
|
TRIM22
|
tripartite motif containing 22 |
| chr3_-_149510553 | 13.99 |
ENST00000462519.2
ENST00000446160.1 ENST00000383050.3 |
ANKUB1
|
ankyrin repeat and ubiquitin domain containing 1 |
| chr1_-_209824643 | 13.81 |
ENST00000391911.1
ENST00000415782.1 |
LAMB3
|
laminin, beta 3 |
| chr8_-_49833978 | 13.77 |
ENST00000020945.1
|
SNAI2
|
snail family zinc finger 2 |
| chr1_+_35220613 | 13.47 |
ENST00000338513.1
|
GJB5
|
gap junction protein, beta 5, 31.1kDa |
| chr16_+_57653596 | 13.42 |
ENST00000568791.1
ENST00000570044.1 |
GPR56
|
G protein-coupled receptor 56 |
| chr1_+_158979792 | 12.98 |
ENST00000359709.3
ENST00000430894.2 |
IFI16
|
interferon, gamma-inducible protein 16 |
| chr6_+_54711533 | 12.90 |
ENST00000306858.7
|
FAM83B
|
family with sequence similarity 83, member B |
| chr1_+_158979686 | 12.72 |
ENST00000368132.3
ENST00000295809.7 |
IFI16
|
interferon, gamma-inducible protein 16 |
| chr1_+_158979680 | 12.50 |
ENST00000368131.4
ENST00000340979.6 |
IFI16
|
interferon, gamma-inducible protein 16 |
| chr16_+_57653625 | 12.45 |
ENST00000567553.1
ENST00000565314.1 |
GPR56
|
G protein-coupled receptor 56 |
| chr6_+_35265586 | 12.38 |
ENST00000542066.1
ENST00000316637.5 |
DEF6
|
differentially expressed in FDCP 6 homolog (mouse) |
| chr1_-_1356719 | 12.17 |
ENST00000520296.1
|
ANKRD65
|
ankyrin repeat domain 65 |
| chr22_+_38302285 | 11.77 |
ENST00000215957.6
|
MICALL1
|
MICAL-like 1 |
| chr1_-_1356628 | 11.60 |
ENST00000442470.1
ENST00000537107.1 |
ANKRD65
|
ankyrin repeat domain 65 |
| chr15_+_41136369 | 10.86 |
ENST00000563656.1
|
SPINT1
|
serine peptidase inhibitor, Kunitz type 1 |
| chr12_+_69202795 | 10.84 |
ENST00000539479.1
ENST00000393415.3 ENST00000523991.1 ENST00000543323.1 ENST00000393416.2 |
MDM2
|
MDM2 oncogene, E3 ubiquitin protein ligase |
| chr12_-_15114191 | 10.73 |
ENST00000541380.1
|
ARHGDIB
|
Rho GDP dissociation inhibitor (GDI) beta |
| chr2_+_208104351 | 10.44 |
ENST00000440326.1
|
AC007879.7
|
AC007879.7 |
| chrX_+_9880412 | 10.22 |
ENST00000418909.2
|
SHROOM2
|
shroom family member 2 |
| chr14_+_51955831 | 10.20 |
ENST00000356218.4
|
FRMD6
|
FERM domain containing 6 |
| chr1_+_24645915 | 9.50 |
ENST00000350501.5
|
GRHL3
|
grainyhead-like 3 (Drosophila) |
| chr11_-_104972158 | 9.21 |
ENST00000598974.1
ENST00000593315.1 ENST00000594519.1 ENST00000415981.2 ENST00000525374.1 ENST00000375707.1 |
CASP1
CARD16
CARD17
|
caspase 1, apoptosis-related cysteine peptidase caspase recruitment domain family, member 16 caspase recruitment domain family, member 17 |
| chrX_+_3189861 | 9.08 |
ENST00000457435.1
ENST00000420429.2 |
CXorf28
|
chromosome X open reading frame 28 |
| chr19_-_9811347 | 9.07 |
ENST00000585964.1
ENST00000457674.2 ENST00000590544.1 |
ZNF812
|
zinc finger protein 812 |
| chr2_-_216003127 | 8.99 |
ENST00000412081.1
ENST00000272895.7 |
ABCA12
|
ATP-binding cassette, sub-family A (ABC1), member 12 |
| chr6_+_18387570 | 8.96 |
ENST00000259939.3
|
RNF144B
|
ring finger protein 144B |
| chr11_-_104905840 | 8.90 |
ENST00000526568.1
ENST00000393136.4 ENST00000531166.1 ENST00000534497.1 ENST00000527979.1 ENST00000446369.1 ENST00000353247.5 ENST00000528974.1 ENST00000533400.1 ENST00000525825.1 ENST00000436863.3 |
CASP1
|
caspase 1, apoptosis-related cysteine peptidase |
| chr1_+_116915270 | 8.73 |
ENST00000418797.1
|
ATP1A1
|
ATPase, Na+/K+ transporting, alpha 1 polypeptide |
| chr8_+_22437664 | 8.50 |
ENST00000436754.1
ENST00000426493.1 ENST00000429812.1 |
PDLIM2
|
PDZ and LIM domain 2 (mystique) |
| chr19_-_11688500 | 8.49 |
ENST00000433365.2
|
ACP5
|
acid phosphatase 5, tartrate resistant |
| chrX_+_152086373 | 8.25 |
ENST00000318529.8
|
ZNF185
|
zinc finger protein 185 (LIM domain) |
| chr10_+_99344104 | 8.13 |
ENST00000555577.1
ENST00000370649.3 |
PI4K2A
PI4K2A
|
phosphatidylinositol 4-kinase type 2 alpha Phosphatidylinositol 4-kinase type 2-alpha; Uncharacterized protein |
| chr19_-_51471381 | 8.12 |
ENST00000594641.1
|
KLK6
|
kallikrein-related peptidase 6 |
| chr2_+_234600253 | 8.00 |
ENST00000373424.1
ENST00000441351.1 |
UGT1A6
|
UDP glucuronosyltransferase 1 family, polypeptide A6 |
| chr8_-_37351424 | 7.95 |
ENST00000522718.1
|
RP11-150O12.1
|
RP11-150O12.1 |
| chr19_-_11688260 | 7.84 |
ENST00000590832.1
|
ACP5
|
acid phosphatase 5, tartrate resistant |
| chr16_+_57653989 | 7.76 |
ENST00000567835.1
ENST00000569372.1 ENST00000563548.1 ENST00000562003.1 |
GPR56
|
G protein-coupled receptor 56 |
| chr1_+_24646002 | 7.63 |
ENST00000356046.2
|
GRHL3
|
grainyhead-like 3 (Drosophila) |
| chr1_+_24645865 | 7.54 |
ENST00000342072.4
|
GRHL3
|
grainyhead-like 3 (Drosophila) |
| chr15_+_78558523 | 7.43 |
ENST00000446172.2
|
DNAJA4
|
DnaJ (Hsp40) homolog, subfamily A, member 4 |
| chr20_-_6103666 | 7.41 |
ENST00000536936.1
|
FERMT1
|
fermitin family member 1 |
| chr6_-_150212029 | 7.38 |
ENST00000529948.1
ENST00000357183.4 ENST00000367363.3 |
RAET1E
|
retinoic acid early transcript 1E |
| chr1_+_24645807 | 7.21 |
ENST00000361548.4
|
GRHL3
|
grainyhead-like 3 (Drosophila) |
| chr8_+_22960426 | 7.08 |
ENST00000540813.1
|
TNFRSF10C
|
tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain |
| chr19_-_51530916 | 7.05 |
ENST00000594768.1
|
KLK11
|
kallikrein-related peptidase 11 |
| chr5_-_42811986 | 7.04 |
ENST00000511224.1
ENST00000507920.1 ENST00000510965.1 |
SEPP1
|
selenoprotein P, plasma, 1 |
| chr16_+_82090028 | 7.01 |
ENST00000568090.1
|
HSD17B2
|
hydroxysteroid (17-beta) dehydrogenase 2 |
| chr9_+_124088860 | 6.97 |
ENST00000373806.1
|
GSN
|
gelsolin |
| chr1_-_117753540 | 6.96 |
ENST00000328189.3
ENST00000369458.3 |
VTCN1
|
V-set domain containing T cell activation inhibitor 1 |
| chr4_+_3388057 | 6.81 |
ENST00000538395.1
|
RGS12
|
regulator of G-protein signaling 12 |
| chr7_+_63774321 | 6.76 |
ENST00000423484.2
|
ZNF736
|
zinc finger protein 736 |
| chr1_+_17575584 | 6.56 |
ENST00000375460.3
|
PADI3
|
peptidyl arginine deiminase, type III |
| chr19_-_11688447 | 6.51 |
ENST00000590420.1
|
ACP5
|
acid phosphatase 5, tartrate resistant |
| chr17_+_26662679 | 6.38 |
ENST00000578158.1
|
TNFAIP1
|
tumor necrosis factor, alpha-induced protein 1 (endothelial) |
| chr2_-_151344172 | 6.24 |
ENST00000375734.2
ENST00000263895.4 ENST00000454202.1 |
RND3
|
Rho family GTPase 3 |
| chr2_-_165698662 | 6.18 |
ENST00000194871.6
ENST00000445474.2 |
COBLL1
|
cordon-bleu WH2 repeat protein-like 1 |
| chr18_+_21033239 | 6.12 |
ENST00000581585.1
ENST00000577501.1 |
RIOK3
|
RIO kinase 3 |
| chr1_+_24646263 | 6.02 |
ENST00000524724.1
|
GRHL3
|
grainyhead-like 3 (Drosophila) |
| chr3_-_45017609 | 6.02 |
ENST00000342790.4
ENST00000424952.2 ENST00000296127.3 ENST00000455235.1 |
ZDHHC3
|
zinc finger, DHHC-type containing 3 |
| chr5_-_42812143 | 5.93 |
ENST00000514985.1
|
SEPP1
|
selenoprotein P, plasma, 1 |
| chr3_-_57113314 | 5.84 |
ENST00000338458.4
ENST00000468727.1 |
ARHGEF3
|
Rho guanine nucleotide exchange factor (GEF) 3 |
| chr15_+_41136263 | 5.81 |
ENST00000568823.1
|
SPINT1
|
serine peptidase inhibitor, Kunitz type 1 |
| chr19_-_19051103 | 5.80 |
ENST00000542541.2
ENST00000433218.2 |
HOMER3
|
homer homolog 3 (Drosophila) |
| chr2_-_165698521 | 5.61 |
ENST00000409184.3
ENST00000392717.2 ENST00000456693.1 |
COBLL1
|
cordon-bleu WH2 repeat protein-like 1 |
| chr1_-_228603694 | 5.56 |
ENST00000366697.2
|
TRIM17
|
tripartite motif containing 17 |
| chr5_-_160365601 | 5.55 |
ENST00000518580.1
ENST00000518301.1 |
RP11-109J4.1
|
RP11-109J4.1 |
| chr11_-_111782696 | 5.46 |
ENST00000227251.3
ENST00000526180.1 |
CRYAB
|
crystallin, alpha B |
| chr12_+_69202975 | 5.46 |
ENST00000544561.1
ENST00000393410.1 ENST00000299252.4 ENST00000360430.2 ENST00000517852.1 ENST00000545204.1 ENST00000393413.3 ENST00000350057.5 ENST00000348801.2 ENST00000478070.1 |
MDM2
|
MDM2 oncogene, E3 ubiquitin protein ligase |
| chr16_+_57653854 | 5.44 |
ENST00000568908.1
ENST00000568909.1 ENST00000566778.1 ENST00000561988.1 |
GPR56
|
G protein-coupled receptor 56 |
| chr6_+_32939964 | 5.31 |
ENST00000607833.1
|
BRD2
|
bromodomain containing 2 |
| chr8_-_37351344 | 5.26 |
ENST00000520422.1
|
RP11-150O12.1
|
RP11-150O12.1 |
| chr1_+_85527987 | 5.21 |
ENST00000326813.8
ENST00000294664.6 ENST00000528899.1 |
WDR63
|
WD repeat domain 63 |
| chrX_+_2670153 | 5.21 |
ENST00000509484.2
|
XG
|
Xg blood group |
| chr3_-_50340996 | 5.01 |
ENST00000266031.4
ENST00000395143.2 ENST00000457214.2 ENST00000447605.2 ENST00000418723.1 ENST00000395144.2 |
HYAL1
|
hyaluronoglucosaminidase 1 |
| chr10_+_90750493 | 4.97 |
ENST00000357339.2
ENST00000355279.2 |
FAS
|
Fas cell surface death receptor |
| chr12_-_88974236 | 4.82 |
ENST00000228280.5
ENST00000552044.1 ENST00000357116.4 |
KITLG
|
KIT ligand |
| chr9_+_93589734 | 4.81 |
ENST00000375746.1
|
SYK
|
spleen tyrosine kinase |
| chr19_-_12662314 | 4.76 |
ENST00000339282.7
ENST00000596193.1 |
ZNF564
|
zinc finger protein 564 |
| chr16_+_8807419 | 4.76 |
ENST00000565016.1
ENST00000567812.1 |
ABAT
|
4-aminobutyrate aminotransferase |
| chr13_+_76334498 | 4.70 |
ENST00000534657.1
|
LMO7
|
LIM domain 7 |
| chrX_+_153029633 | 4.60 |
ENST00000538966.1
ENST00000361971.5 ENST00000538776.1 ENST00000538543.1 |
PLXNB3
|
plexin B3 |
| chr16_-_75467318 | 4.58 |
ENST00000283882.3
|
CFDP1
|
craniofacial development protein 1 |
| chr1_-_19229248 | 4.55 |
ENST00000375341.3
|
ALDH4A1
|
aldehyde dehydrogenase 4 family, member A1 |
| chr18_+_34124507 | 4.53 |
ENST00000591635.1
|
FHOD3
|
formin homology 2 domain containing 3 |
| chr4_+_2794750 | 4.47 |
ENST00000452765.2
ENST00000389838.2 |
SH3BP2
|
SH3-domain binding protein 2 |
| chrX_+_9880590 | 4.46 |
ENST00000452575.1
|
SHROOM2
|
shroom family member 2 |
| chr11_-_7985193 | 4.43 |
ENST00000328600.2
|
NLRP10
|
NLR family, pyrin domain containing 10 |
| chr1_+_12040238 | 4.35 |
ENST00000444836.1
ENST00000235329.5 |
MFN2
|
mitofusin 2 |
| chr11_+_64950801 | 4.35 |
ENST00000526468.1
|
CAPN1
|
calpain 1, (mu/I) large subunit |
| chr9_+_35906176 | 4.33 |
ENST00000354323.2
|
HRCT1
|
histidine rich carboxyl terminus 1 |
| chr16_+_58010339 | 4.22 |
ENST00000290871.5
ENST00000441824.2 |
TEPP
|
testis, prostate and placenta expressed |
| chr7_-_150020814 | 4.13 |
ENST00000477871.1
|
ACTR3C
|
ARP3 actin-related protein 3 homolog C (yeast) |
| chr14_-_73924954 | 4.13 |
ENST00000555307.1
ENST00000554818.1 |
NUMB
|
numb homolog (Drosophila) |
| chr1_-_19229014 | 4.12 |
ENST00000538839.1
ENST00000290597.5 |
ALDH4A1
|
aldehyde dehydrogenase 4 family, member A1 |
| chr19_-_58400148 | 4.12 |
ENST00000595048.1
ENST00000600634.1 ENST00000595295.1 ENST00000596604.1 ENST00000597342.1 ENST00000597807.1 |
ZNF814
|
zinc finger protein 814 |
| chr7_-_150020750 | 4.07 |
ENST00000539352.1
|
ACTR3C
|
ARP3 actin-related protein 3 homolog C (yeast) |
| chr3_-_69590486 | 4.05 |
ENST00000497880.1
|
FRMD4B
|
FERM domain containing 4B |
| chr17_+_75450075 | 4.03 |
ENST00000592951.1
|
SEPT9
|
septin 9 |
| chr17_+_75450099 | 4.03 |
ENST00000586433.1
|
SEPT9
|
septin 9 |
| chr6_-_109330702 | 3.97 |
ENST00000356644.7
|
SESN1
|
sestrin 1 |
| chr17_+_38337491 | 3.96 |
ENST00000538981.1
|
RAPGEFL1
|
Rap guanine nucleotide exchange factor (GEF)-like 1 |
| chr10_+_11059826 | 3.95 |
ENST00000450189.1
|
CELF2
|
CUGBP, Elav-like family member 2 |
| chr5_+_125798031 | 3.94 |
ENST00000502348.1
|
GRAMD3
|
GRAM domain containing 3 |
| chr6_-_101329191 | 3.94 |
ENST00000324723.6
ENST00000369162.2 ENST00000522650.1 |
ASCC3
|
activating signal cointegrator 1 complex subunit 3 |
| chr15_-_42448788 | 3.93 |
ENST00000382396.4
ENST00000397272.3 |
PLA2G4F
|
phospholipase A2, group IVF |
| chr13_+_42846272 | 3.91 |
ENST00000025301.2
|
AKAP11
|
A kinase (PRKA) anchor protein 11 |
| chr21_-_27462351 | 3.88 |
ENST00000448850.1
|
APP
|
amyloid beta (A4) precursor protein |
| chr3_-_57113281 | 3.85 |
ENST00000468466.1
|
ARHGEF3
|
Rho guanine nucleotide exchange factor (GEF) 3 |
| chr17_-_79818354 | 3.84 |
ENST00000576541.1
ENST00000576380.1 ENST00000571617.1 ENST00000576052.1 ENST00000576390.1 ENST00000573778.2 ENST00000439918.2 ENST00000574914.1 ENST00000331483.4 |
P4HB
|
prolyl 4-hydroxylase, beta polypeptide |
| chr5_-_132073210 | 3.76 |
ENST00000378735.1
ENST00000378746.4 |
KIF3A
|
kinesin family member 3A |
| chr17_+_75450146 | 3.72 |
ENST00000585929.1
ENST00000590917.1 |
SEPT9
|
septin 9 |
| chr17_-_79817091 | 3.67 |
ENST00000570907.1
|
P4HB
|
prolyl 4-hydroxylase, beta polypeptide |
| chr13_+_103459704 | 3.60 |
ENST00000602836.1
|
BIVM-ERCC5
|
BIVM-ERCC5 readthrough |
| chr15_-_55700216 | 3.58 |
ENST00000569205.1
|
CCPG1
|
cell cycle progression 1 |
| chr12_+_119616447 | 3.57 |
ENST00000281938.2
|
HSPB8
|
heat shock 22kDa protein 8 |
| chr15_-_55700522 | 3.55 |
ENST00000564092.1
ENST00000310958.6 |
CCPG1
|
cell cycle progression 1 |
| chr9_-_70488865 | 3.54 |
ENST00000377392.5
|
CBWD5
|
COBW domain containing 5 |
| chr7_+_63505799 | 3.46 |
ENST00000550760.3
|
ZNF727
|
zinc finger protein 727 |
| chr4_-_13629269 | 3.44 |
ENST00000040738.5
|
BOD1L1
|
biorientation of chromosomes in cell division 1-like 1 |
| chr16_-_75467274 | 3.41 |
ENST00000566254.1
|
CFDP1
|
craniofacial development protein 1 |
| chrX_-_8700171 | 3.35 |
ENST00000262648.3
|
KAL1
|
Kallmann syndrome 1 sequence |
| chr8_+_21881636 | 3.33 |
ENST00000520125.1
ENST00000521157.1 ENST00000397940.1 ENST00000522813.1 |
NPM2
|
nucleophosmin/nucleoplasmin 2 |
| chr19_-_11688951 | 3.28 |
ENST00000589792.1
|
ACP5
|
acid phosphatase 5, tartrate resistant |
| chr1_-_185286461 | 3.27 |
ENST00000367498.3
|
IVNS1ABP
|
influenza virus NS1A binding protein |
| chr11_-_111782484 | 3.23 |
ENST00000533971.1
|
CRYAB
|
crystallin, alpha B |
| chr4_+_2794785 | 3.18 |
ENST00000503219.1
|
SH3BP2
|
SH3-domain binding protein 2 |
| chr17_+_26662597 | 3.16 |
ENST00000544907.2
|
TNFAIP1
|
tumor necrosis factor, alpha-induced protein 1 (endothelial) |
| chr6_+_148663729 | 3.16 |
ENST00000367467.3
|
SASH1
|
SAM and SH3 domain containing 1 |
| chr19_+_12305824 | 3.07 |
ENST00000415793.1
ENST00000440004.1 ENST00000426044.1 |
CTD-2666L21.1
|
CTD-2666L21.1 |
| chr9_+_71944241 | 3.00 |
ENST00000257515.8
|
FAM189A2
|
family with sequence similarity 189, member A2 |
| chr10_+_124134201 | 2.95 |
ENST00000368990.3
ENST00000368988.1 ENST00000368989.2 ENST00000463663.2 |
PLEKHA1
|
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 |
| chr16_+_23652773 | 2.94 |
ENST00000563998.1
ENST00000568589.1 ENST00000568272.1 |
DCTN5
|
dynactin 5 (p25) |
| chr21_+_44313375 | 2.90 |
ENST00000354250.2
ENST00000340344.4 |
NDUFV3
|
NADH dehydrogenase (ubiquinone) flavoprotein 3, 10kDa |
| chr8_+_22853345 | 2.89 |
ENST00000522948.1
|
RHOBTB2
|
Rho-related BTB domain containing 2 |
| chr22_-_36925124 | 2.86 |
ENST00000457241.1
|
EIF3D
|
eukaryotic translation initiation factor 3, subunit D |
| chr3_-_69101413 | 2.86 |
ENST00000398559.2
|
TMF1
|
TATA element modulatory factor 1 |
| chr2_+_95873257 | 2.76 |
ENST00000425953.1
|
AC092835.2
|
AC092835.2 |
| chr1_-_220263096 | 2.76 |
ENST00000463953.1
ENST00000354807.3 ENST00000414869.2 ENST00000498237.2 ENST00000498791.2 ENST00000544404.1 ENST00000480959.2 ENST00000322067.7 |
BPNT1
|
3'(2'), 5'-bisphosphate nucleotidase 1 |
| chr15_+_40532058 | 2.75 |
ENST00000260404.4
|
PAK6
|
p21 protein (Cdc42/Rac)-activated kinase 6 |
| chr10_+_5726764 | 2.73 |
ENST00000328090.5
ENST00000496681.1 |
FAM208B
|
family with sequence similarity 208, member B |
| chr20_-_43743790 | 2.73 |
ENST00000307971.4
ENST00000372789.4 |
WFDC5
|
WAP four-disulfide core domain 5 |
| chrX_+_48334549 | 2.66 |
ENST00000019019.2
ENST00000348411.2 ENST00000396894.4 |
FTSJ1
|
FtsJ RNA methyltransferase homolog 1 (E. coli) |
| chr15_+_42697065 | 2.58 |
ENST00000565559.1
|
CAPN3
|
calpain 3, (p94) |
| chr1_+_26872324 | 2.55 |
ENST00000531382.1
|
RPS6KA1
|
ribosomal protein S6 kinase, 90kDa, polypeptide 1 |
| chr4_+_6784401 | 2.54 |
ENST00000425103.1
ENST00000307659.5 |
KIAA0232
|
KIAA0232 |
| chr1_-_118727781 | 2.53 |
ENST00000336338.5
|
SPAG17
|
sperm associated antigen 17 |
| chr17_-_74707037 | 2.50 |
ENST00000355797.3
ENST00000375036.2 ENST00000449428.2 |
MXRA7
|
matrix-remodelling associated 7 |
| chr11_+_27062272 | 2.47 |
ENST00000529202.1
ENST00000533566.1 |
BBOX1
|
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 |
| chr5_+_125935960 | 2.43 |
ENST00000297540.4
|
PHAX
|
phosphorylated adaptor for RNA export |
| chr7_-_150020578 | 2.42 |
ENST00000478393.1
|
ACTR3C
|
ARP3 actin-related protein 3 homolog C (yeast) |
| chr15_-_55700457 | 2.40 |
ENST00000442196.3
ENST00000563171.1 ENST00000425574.3 |
CCPG1
|
cell cycle progression 1 |
| chr13_+_27825706 | 2.40 |
ENST00000272274.4
ENST00000319826.4 ENST00000326092.4 |
RPL21
|
ribosomal protein L21 |
| chr14_-_73925225 | 2.37 |
ENST00000356296.4
ENST00000355058.3 ENST00000359560.3 ENST00000557597.1 ENST00000554394.1 ENST00000555238.1 ENST00000535282.1 ENST00000555987.1 ENST00000555394.1 ENST00000554546.1 |
NUMB
|
numb homolog (Drosophila) |
| chr3_-_69101461 | 2.35 |
ENST00000543976.1
|
TMF1
|
TATA element modulatory factor 1 |
| chr7_-_75115548 | 2.34 |
ENST00000453279.2
|
POM121C
|
POM121 transmembrane nucleoporin C |
| chr6_-_30712313 | 2.32 |
ENST00000376377.2
ENST00000259874.5 |
IER3
|
immediate early response 3 |
| chr2_+_217524323 | 2.30 |
ENST00000456764.1
|
IGFBP2
|
insulin-like growth factor binding protein 2, 36kDa |
| chr15_+_42697018 | 2.29 |
ENST00000397204.4
|
CAPN3
|
calpain 3, (p94) |
| chr10_+_103113840 | 2.29 |
ENST00000393441.4
ENST00000408038.2 |
BTRC
|
beta-transducin repeat containing E3 ubiquitin protein ligase |
| chr10_+_75532028 | 2.27 |
ENST00000372841.3
ENST00000394790.1 |
FUT11
|
fucosyltransferase 11 (alpha (1,3) fucosyltransferase) |
| chr4_+_39699664 | 2.27 |
ENST00000261427.5
ENST00000510934.1 ENST00000295963.6 |
UBE2K
|
ubiquitin-conjugating enzyme E2K |
| chr11_+_77899842 | 2.25 |
ENST00000530267.1
|
USP35
|
ubiquitin specific peptidase 35 |
| chr15_+_40226304 | 2.24 |
ENST00000559624.1
ENST00000382727.2 ENST00000263791.5 ENST00000560648.1 |
EIF2AK4
|
eukaryotic translation initiation factor 2 alpha kinase 4 |
| chr4_+_71554196 | 2.20 |
ENST00000254803.2
|
UTP3
|
UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae) |
| chr13_+_42712178 | 2.18 |
ENST00000536612.1
|
DGKH
|
diacylglycerol kinase, eta |
| chr1_+_20959943 | 2.16 |
ENST00000321556.4
|
PINK1
|
PTEN induced putative kinase 1 |
| chr11_+_77899920 | 2.16 |
ENST00000528910.1
ENST00000529308.1 |
USP35
|
ubiquitin specific peptidase 35 |
| chr8_-_23021533 | 2.11 |
ENST00000312584.3
|
TNFRSF10D
|
tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain |
| chr5_-_64920115 | 2.07 |
ENST00000381018.3
ENST00000274327.7 |
TRIM23
|
tripartite motif containing 23 |
| chr19_-_12405689 | 2.07 |
ENST00000355684.5
|
ZNF44
|
zinc finger protein 44 |
| chr15_+_42696992 | 2.05 |
ENST00000561817.1
|
CAPN3
|
calpain 3, (p94) |
| chr19_-_46288917 | 2.01 |
ENST00000537879.1
ENST00000596586.1 ENST00000595946.1 |
DMWD
AC011530.4
|
dystrophia myotonica, WD repeat containing Uncharacterized protein |
| chrX_-_129244336 | 1.98 |
ENST00000434609.1
|
ELF4
|
E74-like factor 4 (ets domain transcription factor) |
| chr2_+_131369054 | 1.96 |
ENST00000409602.1
|
POTEJ
|
POTE ankyrin domain family, member J |
| chr21_-_33104367 | 1.95 |
ENST00000286835.7
ENST00000399804.1 |
SCAF4
|
SR-related CTD-associated factor 4 |
| chr7_+_75024903 | 1.94 |
ENST00000323819.3
ENST00000430211.1 |
TRIM73
|
tripartite motif containing 73 |
| chr7_+_80267973 | 1.93 |
ENST00000394788.3
ENST00000447544.2 |
CD36
|
CD36 molecule (thrombospondin receptor) |
| chr10_+_103113802 | 1.92 |
ENST00000370187.3
|
BTRC
|
beta-transducin repeat containing E3 ubiquitin protein ligase |
| chr15_+_68570062 | 1.90 |
ENST00000306917.4
|
FEM1B
|
fem-1 homolog b (C. elegans) |
Network of associatons between targets according to the STRING database.
First level regulatory network of TP63
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 12.1 | 84.4 | GO:0071461 | cellular response to redox state(GO:0071461) |
| 8.5 | 33.9 | GO:0051710 | cytolysis by symbiont of host cells(GO:0001897) regulation of cytolysis in other organism(GO:0051710) |
| 8.3 | 33.0 | GO:0001808 | negative regulation of type IV hypersensitivity(GO:0001808) |
| 8.1 | 32.4 | GO:0060166 | olfactory pit development(GO:0060166) |
| 5.4 | 16.3 | GO:0071301 | cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404) |
| 4.9 | 14.7 | GO:0008057 | eye pigment granule organization(GO:0008057) |
| 4.6 | 13.8 | GO:0070563 | negative regulation of vitamin D receptor signaling pathway(GO:0070563) |
| 4.5 | 18.1 | GO:0050717 | positive regulation of interleukin-1 alpha secretion(GO:0050717) |
| 3.3 | 26.1 | GO:0032929 | negative regulation of superoxide anion generation(GO:0032929) |
| 2.7 | 8.1 | GO:0002276 | basophil activation involved in immune response(GO:0002276) |
| 2.7 | 13.5 | GO:0060708 | spongiotrophoblast differentiation(GO:0060708) |
| 2.2 | 9.0 | GO:0035627 | ceramide transport(GO:0035627) |
| 1.6 | 6.5 | GO:0021849 | neuroblast division in subventricular zone(GO:0021849) |
| 1.6 | 4.8 | GO:0033023 | mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668) |
| 1.6 | 9.5 | GO:2001106 | regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106) |
| 1.6 | 37.9 | GO:0090179 | planar cell polarity pathway involved in neural tube closure(GO:0090179) |
| 1.4 | 10.0 | GO:0010133 | proline catabolic process to glutamate(GO:0010133) |
| 1.4 | 7.0 | GO:0044855 | plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906) |
| 1.3 | 6.6 | GO:0036414 | protein citrullination(GO:0018101) histone citrullination(GO:0036414) |
| 1.3 | 32.7 | GO:0060670 | branching involved in labyrinthine layer morphogenesis(GO:0060670) |
| 1.2 | 7.4 | GO:0048817 | negative regulation of hair follicle maturation(GO:0048817) |
| 1.2 | 6.1 | GO:0039534 | negative regulation of MDA-5 signaling pathway(GO:0039534) |
| 1.2 | 4.8 | GO:0045401 | response to molecule of fungal origin(GO:0002238) serotonin production involved in inflammatory response(GO:0002351) serotonin secretion involved in inflammatory response(GO:0002442) serotonin secretion by platelet(GO:0002554) positive regulation of interleukin-3 production(GO:0032752) interleukin-3 biosynthetic process(GO:0042223) regulation of interleukin-3 biosynthetic process(GO:0045399) positive regulation of interleukin-3 biosynthetic process(GO:0045401) cellular response to molecule of fungal origin(GO:0071226) |
| 1.2 | 7.0 | GO:1900042 | positive regulation of interleukin-2 secretion(GO:1900042) |
| 1.1 | 10.2 | GO:0003383 | apical constriction(GO:0003383) |
| 1.1 | 4.4 | GO:0035397 | helper T cell enhancement of adaptive immune response(GO:0035397) |
| 1.1 | 27.6 | GO:0090026 | positive regulation of monocyte chemotaxis(GO:0090026) |
| 1.1 | 72.7 | GO:0032732 | positive regulation of interleukin-1 production(GO:0032732) |
| 1.0 | 5.2 | GO:2000843 | testosterone secretion(GO:0035936) regulation of testosterone secretion(GO:2000843) positive regulation of testosterone secretion(GO:2000845) |
| 1.0 | 4.1 | GO:0001732 | formation of cytoplasmic translation initiation complex(GO:0001732) |
| 1.0 | 5.0 | GO:1900106 | hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106) |
| 1.0 | 6.9 | GO:0014718 | positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718) |
| 1.0 | 46.3 | GO:0060512 | prostate gland morphogenesis(GO:0060512) |
| 1.0 | 4.8 | GO:1904448 | negative regulation of gamma-aminobutyric acid secretion(GO:0014053) aspartate secretion(GO:0061528) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450) |
| 0.8 | 8.7 | GO:0090032 | negative regulation of glucocorticoid metabolic process(GO:0031944) negative regulation of glucocorticoid biosynthetic process(GO:0031947) negative regulation of steroid hormone biosynthetic process(GO:0090032) |
| 0.8 | 3.9 | GO:0071874 | cellular response to norepinephrine stimulus(GO:0071874) |
| 0.8 | 7.5 | GO:0046598 | positive regulation of viral entry into host cell(GO:0046598) |
| 0.7 | 2.2 | GO:0071262 | regulation of eIF2 alpha phosphorylation by amino acid starvation(GO:0060733) regulation of translational initiation in response to starvation(GO:0071262) positive regulation of translational initiation in response to starvation(GO:0071264) |
| 0.7 | 8.0 | GO:2000270 | negative regulation of fibroblast apoptotic process(GO:2000270) |
| 0.7 | 2.2 | GO:1902958 | neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036482) positive regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902958) regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903383) negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903384) |
| 0.7 | 5.0 | GO:0097527 | necroptotic signaling pathway(GO:0097527) |
| 0.7 | 14.7 | GO:0046415 | urate metabolic process(GO:0046415) |
| 0.6 | 1.9 | GO:0060406 | positive regulation of penile erection(GO:0060406) |
| 0.6 | 8.0 | GO:0052697 | flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697) |
| 0.6 | 2.4 | GO:0006408 | snRNA export from nucleus(GO:0006408) |
| 0.6 | 16.3 | GO:0051639 | actin filament network formation(GO:0051639) |
| 0.5 | 2.5 | GO:1904158 | axonemal central apparatus assembly(GO:1904158) |
| 0.5 | 1.5 | GO:0019516 | lactate oxidation(GO:0019516) |
| 0.5 | 8.1 | GO:0016540 | protein autoprocessing(GO:0016540) |
| 0.5 | 2.4 | GO:0009608 | response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609) |
| 0.4 | 13.4 | GO:0036010 | protein localization to endosome(GO:0036010) |
| 0.4 | 4.6 | GO:0010593 | negative regulation of lamellipodium assembly(GO:0010593) |
| 0.4 | 1.2 | GO:0021648 | vestibulocochlear nerve morphogenesis(GO:0021648) vestibulocochlear nerve formation(GO:0021650) |
| 0.4 | 3.2 | GO:1902498 | regulation of protein autoubiquitination(GO:1902498) |
| 0.4 | 1.6 | GO:0071284 | cellular response to lead ion(GO:0071284) |
| 0.4 | 7.4 | GO:0090084 | negative regulation of inclusion body assembly(GO:0090084) |
| 0.4 | 2.6 | GO:2000491 | positive regulation of hepatic stellate cell activation(GO:2000491) |
| 0.4 | 13.4 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
| 0.4 | 2.5 | GO:0070383 | DNA cytosine deamination(GO:0070383) |
| 0.3 | 8.7 | GO:0007021 | tubulin complex assembly(GO:0007021) |
| 0.3 | 11.8 | GO:1902857 | positive regulation of nonmotile primary cilium assembly(GO:1902857) |
| 0.3 | 1.4 | GO:0046116 | queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116) |
| 0.3 | 5.3 | GO:0006307 | DNA dealkylation involved in DNA repair(GO:0006307) |
| 0.3 | 7.0 | GO:0006703 | estrogen biosynthetic process(GO:0006703) |
| 0.3 | 9.7 | GO:0007398 | ectoderm development(GO:0007398) |
| 0.3 | 24.8 | GO:0018149 | peptide cross-linking(GO:0018149) |
| 0.3 | 10.7 | GO:0035024 | negative regulation of Rho protein signal transduction(GO:0035024) |
| 0.3 | 1.2 | GO:0034476 | U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476) |
| 0.3 | 4.3 | GO:0097264 | self proteolysis(GO:0097264) |
| 0.3 | 3.8 | GO:0072383 | plus-end-directed vesicle transport along microtubule(GO:0072383) |
| 0.3 | 1.9 | GO:0031642 | negative regulation of myelination(GO:0031642) |
| 0.3 | 1.5 | GO:0090131 | mesenchyme migration(GO:0090131) |
| 0.2 | 3.0 | GO:0001866 | NK T cell proliferation(GO:0001866) |
| 0.2 | 4.0 | GO:1904262 | negative regulation of TORC1 signaling(GO:1904262) |
| 0.2 | 1.6 | GO:1903786 | mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788) |
| 0.2 | 1.8 | GO:0051901 | positive regulation of mitochondrial depolarization(GO:0051901) |
| 0.2 | 1.3 | GO:0031860 | telomeric loop formation(GO:0031627) telomeric 3' overhang formation(GO:0031860) |
| 0.2 | 2.3 | GO:2000332 | blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334) |
| 0.2 | 5.7 | GO:0007216 | G-protein coupled glutamate receptor signaling pathway(GO:0007216) |
| 0.2 | 3.3 | GO:0045836 | positive regulation of meiotic nuclear division(GO:0045836) |
| 0.2 | 4.4 | GO:0034497 | protein localization to pre-autophagosomal structure(GO:0034497) |
| 0.2 | 2.3 | GO:0010994 | regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994) |
| 0.2 | 0.4 | GO:1902174 | positive regulation of keratinocyte apoptotic process(GO:1902174) |
| 0.2 | 2.5 | GO:0045329 | carnitine biosynthetic process(GO:0045329) |
| 0.2 | 10.6 | GO:0034314 | Arp2/3 complex-mediated actin nucleation(GO:0034314) |
| 0.2 | 2.9 | GO:0001553 | luteinization(GO:0001553) |
| 0.2 | 3.9 | GO:0071236 | cellular response to antibiotic(GO:0071236) |
| 0.2 | 1.3 | GO:0048549 | positive regulation of pinocytosis(GO:0048549) |
| 0.2 | 0.5 | GO:0046168 | glycerol-3-phosphate catabolic process(GO:0046168) |
| 0.2 | 1.1 | GO:0035878 | nail development(GO:0035878) |
| 0.2 | 3.2 | GO:0006388 | tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388) |
| 0.1 | 6.0 | GO:0018345 | protein palmitoylation(GO:0018345) |
| 0.1 | 0.7 | GO:0035426 | extracellular matrix-cell signaling(GO:0035426) |
| 0.1 | 23.7 | GO:1902476 | chloride transmembrane transport(GO:1902476) |
| 0.1 | 3.2 | GO:0031573 | intra-S DNA damage checkpoint(GO:0031573) |
| 0.1 | 0.4 | GO:1903367 | positive regulation of fear response(GO:1903367) positive regulation of behavioral fear response(GO:2000987) |
| 0.1 | 7.4 | GO:0001913 | T cell mediated cytotoxicity(GO:0001913) |
| 0.1 | 3.1 | GO:0051865 | protein autoubiquitination(GO:0051865) |
| 0.1 | 0.4 | GO:0048104 | establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105) |
| 0.1 | 3.6 | GO:0006295 | nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295) |
| 0.1 | 9.6 | GO:0070206 | protein trimerization(GO:0070206) |
| 0.1 | 14.2 | GO:0048477 | oogenesis(GO:0048477) |
| 0.1 | 4.2 | GO:0042753 | positive regulation of circadian rhythm(GO:0042753) |
| 0.1 | 1.8 | GO:0038007 | netrin-activated signaling pathway(GO:0038007) |
| 0.1 | 1.5 | GO:0030948 | negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948) |
| 0.1 | 1.3 | GO:1903943 | negative regulation of myoblast fusion(GO:1901740) regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944) |
| 0.1 | 1.4 | GO:0048227 | plasma membrane to endosome transport(GO:0048227) |
| 0.1 | 4.1 | GO:0090162 | establishment of epithelial cell polarity(GO:0090162) |
| 0.1 | 3.9 | GO:0010738 | regulation of protein kinase A signaling(GO:0010738) |
| 0.1 | 2.3 | GO:0010226 | response to lithium ion(GO:0010226) |
| 0.1 | 2.0 | GO:0007250 | activation of NF-kappaB-inducing kinase activity(GO:0007250) |
| 0.1 | 0.3 | GO:1901421 | positive regulation of response to alcohol(GO:1901421) |
| 0.1 | 0.2 | GO:1901053 | sarcosine metabolic process(GO:1901052) sarcosine catabolic process(GO:1901053) |
| 0.1 | 1.3 | GO:0043401 | steroid hormone mediated signaling pathway(GO:0043401) |
| 0.1 | 0.5 | GO:0051594 | detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594) |
| 0.1 | 0.9 | GO:0043951 | negative regulation of cAMP-mediated signaling(GO:0043951) |
| 0.1 | 0.4 | GO:0060681 | branch elongation involved in ureteric bud branching(GO:0060681) |
| 0.1 | 1.8 | GO:0002089 | lens morphogenesis in camera-type eye(GO:0002089) |
| 0.1 | 2.3 | GO:0036065 | fucosylation(GO:0036065) |
| 0.1 | 3.6 | GO:0006376 | mRNA splice site selection(GO:0006376) |
| 0.1 | 2.7 | GO:0030488 | tRNA methylation(GO:0030488) |
| 0.1 | 1.5 | GO:2001014 | regulation of skeletal muscle cell differentiation(GO:2001014) |
| 0.1 | 0.7 | GO:1903142 | positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142) |
| 0.1 | 6.4 | GO:0016579 | protein deubiquitination(GO:0016579) |
| 0.1 | 4.5 | GO:0032496 | response to lipopolysaccharide(GO:0032496) |
| 0.1 | 4.2 | GO:0060976 | coronary vasculature development(GO:0060976) |
| 0.1 | 2.4 | GO:0050427 | purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427) |
| 0.0 | 1.5 | GO:0033540 | fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540) |
| 0.0 | 1.7 | GO:0016578 | histone deubiquitination(GO:0016578) |
| 0.0 | 1.2 | GO:0007614 | short-term memory(GO:0007614) |
| 0.0 | 1.6 | GO:0033962 | cytoplasmic mRNA processing body assembly(GO:0033962) |
| 0.0 | 0.2 | GO:0070213 | protein auto-ADP-ribosylation(GO:0070213) |
| 0.0 | 0.6 | GO:0007258 | JUN phosphorylation(GO:0007258) |
| 0.0 | 0.2 | GO:2000234 | positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234) |
| 0.0 | 5.0 | GO:0032436 | positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) |
| 0.0 | 2.2 | GO:0016569 | covalent chromatin modification(GO:0016569) |
| 0.0 | 1.3 | GO:0000188 | inactivation of MAPK activity(GO:0000188) |
| 0.0 | 1.0 | GO:0031297 | replication fork processing(GO:0031297) |
| 0.0 | 2.7 | GO:0010951 | negative regulation of endopeptidase activity(GO:0010951) |
| 0.0 | 0.5 | GO:0098828 | positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828) |
| 0.0 | 1.8 | GO:0048488 | synaptic vesicle endocytosis(GO:0048488) |
| 0.0 | 9.2 | GO:0007266 | Rho protein signal transduction(GO:0007266) |
| 0.0 | 3.5 | GO:1900034 | regulation of cellular response to heat(GO:1900034) |
| 0.0 | 0.2 | GO:0090063 | positive regulation of microtubule nucleation(GO:0090063) |
| 0.0 | 0.1 | GO:0006781 | succinyl-CoA pathway(GO:0006781) |
| 0.0 | 1.4 | GO:0046473 | phosphatidic acid metabolic process(GO:0046473) |
| 0.0 | 0.6 | GO:0032515 | negative regulation of phosphoprotein phosphatase activity(GO:0032515) |
| 0.0 | 0.2 | GO:0032510 | endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510) |
| 0.0 | 0.5 | GO:0016180 | snRNA processing(GO:0016180) |
| 0.0 | 0.7 | GO:0042776 | mitochondrial ATP synthesis coupled proton transport(GO:0042776) |
| 0.0 | 0.8 | GO:0070271 | protein complex assembly(GO:0006461) protein complex biogenesis(GO:0070271) |
| 0.0 | 1.9 | GO:0006396 | RNA processing(GO:0006396) |
| 0.0 | 2.7 | GO:2001243 | negative regulation of intrinsic apoptotic signaling pathway(GO:2001243) |
| 0.0 | 1.7 | GO:0001895 | retina homeostasis(GO:0001895) |
| 0.0 | 3.8 | GO:0007173 | epidermal growth factor receptor signaling pathway(GO:0007173) |
| 0.0 | 0.3 | GO:0060211 | regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213) |
| 0.0 | 2.3 | GO:0006334 | nucleosome assembly(GO:0006334) |
| 0.0 | 1.3 | GO:0007517 | muscle organ development(GO:0007517) |
| 0.0 | 0.8 | GO:0006968 | cellular defense response(GO:0006968) |
| 0.0 | 2.1 | GO:0014066 | regulation of phosphatidylinositol 3-kinase signaling(GO:0014066) |
| 0.0 | 0.2 | GO:0090266 | regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504) |
| 0.0 | 0.3 | GO:0032012 | ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012) |
| 0.0 | 0.1 | GO:0006308 | DNA catabolic process(GO:0006308) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.6 | 18.1 | GO:0072558 | NLRP1 inflammasome complex(GO:0072558) protease inhibitor complex(GO:0097179) |
| 1.9 | 7.5 | GO:0016222 | procollagen-proline 4-dioxygenase complex(GO:0016222) |
| 1.7 | 5.0 | GO:0036117 | hyaluranon cable(GO:0036117) |
| 1.6 | 8.0 | GO:0035838 | growing cell tip(GO:0035838) |
| 1.3 | 9.0 | GO:0097209 | epidermal lamellar body(GO:0097209) |
| 1.3 | 13.8 | GO:0005610 | laminin-5 complex(GO:0005610) |
| 1.1 | 3.3 | GO:0000229 | cytoplasmic chromosome(GO:0000229) |
| 1.0 | 34.5 | GO:0071682 | endocytic vesicle lumen(GO:0071682) |
| 1.0 | 4.8 | GO:0032144 | 4-aminobutyrate transaminase complex(GO:0032144) |
| 0.9 | 3.8 | GO:0016939 | kinesin II complex(GO:0016939) |
| 0.8 | 2.5 | GO:1990716 | axonemal central apparatus(GO:1990716) |
| 0.7 | 4.8 | GO:0019815 | B cell receptor complex(GO:0019815) |
| 0.6 | 54.3 | GO:0045095 | keratin filament(GO:0045095) |
| 0.5 | 13.9 | GO:0005922 | connexon complex(GO:0005922) |
| 0.5 | 6.1 | GO:0030688 | preribosome, small subunit precursor(GO:0030688) |
| 0.5 | 8.7 | GO:0097512 | cardiac myofibril(GO:0097512) |
| 0.5 | 7.0 | GO:0030478 | actin cap(GO:0030478) |
| 0.5 | 5.1 | GO:0071541 | eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541) |
| 0.5 | 4.5 | GO:0097413 | Lewy body(GO:0097413) |
| 0.4 | 10.6 | GO:0005885 | Arp2/3 protein complex(GO:0005885) |
| 0.4 | 23.9 | GO:0009925 | basal plasma membrane(GO:0009925) |
| 0.4 | 3.9 | GO:1990812 | growth cone filopodium(GO:1990812) |
| 0.3 | 8.7 | GO:0005890 | sodium:potassium-exchanging ATPase complex(GO:0005890) |
| 0.3 | 1.6 | GO:0071942 | XPC complex(GO:0071942) |
| 0.3 | 11.8 | GO:0031105 | septin complex(GO:0031105) |
| 0.3 | 3.2 | GO:0072669 | tRNA-splicing ligase complex(GO:0072669) |
| 0.3 | 21.3 | GO:0001533 | cornified envelope(GO:0001533) |
| 0.3 | 6.3 | GO:0031265 | CD95 death-inducing signaling complex(GO:0031265) |
| 0.3 | 1.5 | GO:0030485 | smooth muscle contractile fiber(GO:0030485) |
| 0.2 | 4.0 | GO:0061700 | GATOR2 complex(GO:0061700) |
| 0.2 | 16.9 | GO:0015030 | Cajal body(GO:0015030) |
| 0.2 | 1.0 | GO:0071008 | U2-type post-mRNA release spliceosomal complex(GO:0071008) |
| 0.2 | 0.9 | GO:0045323 | interleukin-1 receptor complex(GO:0045323) |
| 0.1 | 1.3 | GO:0044354 | pinosome(GO:0044352) macropinosome(GO:0044354) |
| 0.1 | 2.3 | GO:0032433 | filopodium tip(GO:0032433) |
| 0.1 | 11.8 | GO:0055038 | recycling endosome membrane(GO:0055038) |
| 0.1 | 0.8 | GO:1990726 | Lsm1-7-Pat1 complex(GO:1990726) |
| 0.1 | 17.2 | GO:0030175 | filopodium(GO:0030175) |
| 0.1 | 14.7 | GO:0030864 | cortical actin cytoskeleton(GO:0030864) |
| 0.1 | 4.6 | GO:0045178 | basal part of cell(GO:0045178) |
| 0.1 | 1.5 | GO:0016235 | aggresome(GO:0016235) |
| 0.1 | 4.6 | GO:0031941 | filamentous actin(GO:0031941) |
| 0.1 | 0.4 | GO:0060187 | cell pole(GO:0060187) |
| 0.1 | 4.8 | GO:0005865 | striated muscle thin filament(GO:0005865) |
| 0.1 | 1.7 | GO:0000124 | SAGA complex(GO:0000124) STAGA complex(GO:0030914) |
| 0.1 | 3.0 | GO:0031306 | intrinsic component of mitochondrial outer membrane(GO:0031306) |
| 0.1 | 6.8 | GO:0030315 | T-tubule(GO:0030315) |
| 0.1 | 1.2 | GO:0000176 | nuclear exosome (RNase complex)(GO:0000176) |
| 0.1 | 0.5 | GO:0009331 | glycerol-3-phosphate dehydrogenase complex(GO:0009331) |
| 0.1 | 1.4 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
| 0.1 | 0.5 | GO:1990393 | 3M complex(GO:1990393) |
| 0.1 | 7.6 | GO:0000777 | condensed chromosome kinetochore(GO:0000777) |
| 0.1 | 61.6 | GO:0016604 | nuclear body(GO:0016604) |
| 0.1 | 1.1 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
| 0.1 | 8.3 | GO:0043296 | apical junction complex(GO:0043296) |
| 0.0 | 4.2 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
| 0.0 | 4.2 | GO:0032587 | ruffle membrane(GO:0032587) |
| 0.0 | 4.7 | GO:0000794 | condensed nuclear chromosome(GO:0000794) |
| 0.0 | 3.2 | GO:0030286 | dynein complex(GO:0030286) |
| 0.0 | 26.9 | GO:0045177 | apical part of cell(GO:0045177) |
| 0.0 | 4.1 | GO:0001726 | ruffle(GO:0001726) |
| 0.0 | 2.6 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 0.0 | 1.6 | GO:0035861 | site of double-strand break(GO:0035861) |
| 0.0 | 3.8 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 0.0 | 0.5 | GO:0032039 | integrator complex(GO:0032039) |
| 0.0 | 2.2 | GO:0005844 | polysome(GO:0005844) |
| 0.0 | 1.9 | GO:0005694 | chromosome(GO:0005694) |
| 0.0 | 1.8 | GO:0019898 | extrinsic component of membrane(GO:0019898) |
| 0.0 | 8.4 | GO:0000151 | ubiquitin ligase complex(GO:0000151) |
| 0.0 | 6.2 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.0 | 4.4 | GO:0019897 | extrinsic component of plasma membrane(GO:0019897) |
| 0.0 | 3.9 | GO:0005681 | spliceosomal complex(GO:0005681) |
| 0.0 | 0.5 | GO:0060077 | inhibitory synapse(GO:0060077) |
| 0.0 | 0.2 | GO:0097197 | tetraspanin-enriched microdomain(GO:0097197) |
| 0.0 | 109.3 | GO:0070062 | extracellular exosome(GO:0070062) |
| 0.0 | 1.6 | GO:0005801 | cis-Golgi network(GO:0005801) |
| 0.0 | 1.8 | GO:0001669 | acrosomal vesicle(GO:0001669) |
| 0.0 | 5.4 | GO:0015629 | actin cytoskeleton(GO:0015629) |
| 0.0 | 1.5 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
| 0.0 | 0.2 | GO:0000242 | pericentriolar material(GO:0000242) |
| 0.0 | 6.8 | GO:0009986 | cell surface(GO:0009986) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 7.0 | 84.4 | GO:0005094 | Rho GDP-dissociation inhibitor activity(GO:0005094) |
| 5.5 | 33.0 | GO:0042015 | interleukin-20 binding(GO:0042015) |
| 5.4 | 16.3 | GO:0061663 | NEDD8 ligase activity(GO:0061663) |
| 4.3 | 12.9 | GO:0036313 | phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313) |
| 3.3 | 10.0 | GO:0003842 | 1-pyrroline-5-carboxylate dehydrogenase activity(GO:0003842) |
| 2.2 | 9.0 | GO:0034040 | lipid-transporting ATPase activity(GO:0034040) |
| 2.0 | 8.1 | GO:0035651 | AP-3 adaptor complex binding(GO:0035651) |
| 2.0 | 32.4 | GO:0001758 | retinal dehydrogenase activity(GO:0001758) |
| 1.9 | 11.2 | GO:0045569 | TRAIL binding(GO:0045569) |
| 1.5 | 26.1 | GO:0008199 | ferric iron binding(GO:0008199) |
| 1.3 | 14.7 | GO:0015143 | urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702) |
| 1.3 | 6.6 | GO:0004668 | protein-arginine deiminase activity(GO:0004668) |
| 1.2 | 4.8 | GO:0005173 | stem cell factor receptor binding(GO:0005173) |
| 1.2 | 7.0 | GO:0047006 | 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006) |
| 1.1 | 15.3 | GO:0089720 | caspase binding(GO:0089720) |
| 1.0 | 4.1 | GO:0098808 | mRNA cap binding(GO:0098808) |
| 1.0 | 5.0 | GO:0050501 | hyaluronan synthase activity(GO:0050501) |
| 1.0 | 4.8 | GO:0003867 | 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298) |
| 0.9 | 2.8 | GO:0008441 | 3'(2'),5'-bisphosphate nucleotidase activity(GO:0008441) |
| 0.8 | 7.5 | GO:0019798 | procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798) |
| 0.8 | 5.0 | GO:0043120 | tumor necrosis factor binding(GO:0043120) |
| 0.8 | 14.7 | GO:0015280 | ligand-gated sodium channel activity(GO:0015280) |
| 0.7 | 23.0 | GO:0005229 | intracellular calcium activated chloride channel activity(GO:0005229) |
| 0.7 | 4.6 | GO:0051021 | GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022) |
| 0.6 | 34.5 | GO:0042056 | chemoattractant activity(GO:0042056) |
| 0.6 | 2.5 | GO:0008336 | gamma-butyrobetaine dioxygenase activity(GO:0008336) |
| 0.6 | 7.4 | GO:0046703 | natural killer cell lectin-like receptor binding(GO:0046703) |
| 0.6 | 4.0 | GO:0070728 | leucine binding(GO:0070728) |
| 0.6 | 82.5 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.5 | 1.6 | GO:0005150 | interleukin-1, Type I receptor binding(GO:0005150) |
| 0.5 | 1.6 | GO:0000405 | bubble DNA binding(GO:0000405) |
| 0.5 | 1.6 | GO:1904854 | proteasome core complex binding(GO:1904854) |
| 0.5 | 27.6 | GO:0042379 | chemokine receptor binding(GO:0042379) |
| 0.5 | 5.3 | GO:0043140 | ATP-dependent 3'-5' DNA helicase activity(GO:0043140) |
| 0.5 | 1.9 | GO:0031685 | adenosine receptor binding(GO:0031685) |
| 0.5 | 7.0 | GO:0045159 | myosin II binding(GO:0045159) |
| 0.4 | 8.9 | GO:0050700 | CARD domain binding(GO:0050700) |
| 0.4 | 8.7 | GO:1990239 | steroid hormone binding(GO:1990239) |
| 0.4 | 10.8 | GO:0017049 | GTP-Rho binding(GO:0017049) |
| 0.4 | 2.2 | GO:0004694 | eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694) |
| 0.3 | 8.7 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
| 0.3 | 2.7 | GO:0016427 | tRNA (cytosine) methyltransferase activity(GO:0016427) |
| 0.3 | 11.8 | GO:0070300 | phosphatidic acid binding(GO:0070300) |
| 0.3 | 2.5 | GO:0004126 | cytidine deaminase activity(GO:0004126) |
| 0.3 | 1.5 | GO:0004165 | dodecenoyl-CoA delta-isomerase activity(GO:0004165) |
| 0.3 | 6.9 | GO:0031432 | titin binding(GO:0031432) |
| 0.3 | 3.2 | GO:0047498 | calcium-dependent phospholipase A2 activity(GO:0047498) |
| 0.3 | 7.2 | GO:0035325 | Toll-like receptor binding(GO:0035325) |
| 0.3 | 1.4 | GO:0008479 | queuine tRNA-ribosyltransferase activity(GO:0008479) |
| 0.3 | 5.8 | GO:0035256 | G-protein coupled glutamate receptor binding(GO:0035256) |
| 0.3 | 61.6 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
| 0.2 | 8.0 | GO:0001972 | retinoic acid binding(GO:0001972) |
| 0.2 | 5.2 | GO:0045504 | dynein heavy chain binding(GO:0045504) |
| 0.2 | 2.3 | GO:0046920 | alpha-(1->3)-fucosyltransferase activity(GO:0046920) |
| 0.2 | 11.8 | GO:0003785 | actin monomer binding(GO:0003785) |
| 0.2 | 48.8 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
| 0.2 | 2.2 | GO:0055131 | C3HC4-type RING finger domain binding(GO:0055131) |
| 0.2 | 24.5 | GO:0003707 | steroid hormone receptor activity(GO:0003707) |
| 0.2 | 5.0 | GO:0045294 | alpha-catenin binding(GO:0045294) |
| 0.2 | 1.2 | GO:1901612 | cardiolipin binding(GO:1901612) |
| 0.2 | 3.2 | GO:0031435 | mitogen-activated protein kinase kinase kinase binding(GO:0031435) |
| 0.2 | 9.0 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
| 0.2 | 0.5 | GO:0004367 | glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367) |
| 0.2 | 21.3 | GO:0031490 | chromatin DNA binding(GO:0031490) |
| 0.2 | 3.8 | GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) |
| 0.1 | 1.5 | GO:0004459 | L-lactate dehydrogenase activity(GO:0004459) |
| 0.1 | 48.1 | GO:0030674 | protein binding, bridging(GO:0030674) |
| 0.1 | 2.9 | GO:0043325 | phosphatidylinositol-3,4-bisphosphate binding(GO:0043325) |
| 0.1 | 5.3 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
| 0.1 | 2.3 | GO:0034450 | ubiquitin-ubiquitin ligase activity(GO:0034450) |
| 0.1 | 4.3 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity(GO:0004198) |
| 0.1 | 2.4 | GO:0015643 | toxic substance binding(GO:0015643) |
| 0.1 | 3.9 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
| 0.1 | 1.3 | GO:0035312 | 5'-3' exodeoxyribonuclease activity(GO:0035312) |
| 0.1 | 3.2 | GO:0000993 | RNA polymerase II core binding(GO:0000993) |
| 0.1 | 1.9 | GO:0008301 | four-way junction DNA binding(GO:0000400) DNA binding, bending(GO:0008301) |
| 0.1 | 1.8 | GO:0008432 | JUN kinase binding(GO:0008432) |
| 0.1 | 3.2 | GO:0005123 | death receptor binding(GO:0005123) |
| 0.1 | 3.3 | GO:0019706 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707) |
| 0.1 | 1.4 | GO:0004579 | dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
| 0.1 | 1.6 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
| 0.1 | 4.2 | GO:0045309 | protein phosphorylated amino acid binding(GO:0045309) |
| 0.1 | 0.7 | GO:0043237 | laminin-1 binding(GO:0043237) |
| 0.1 | 2.4 | GO:0004602 | glutathione peroxidase activity(GO:0004602) |
| 0.1 | 0.2 | GO:0008480 | sarcosine dehydrogenase activity(GO:0008480) |
| 0.1 | 1.3 | GO:0050291 | sphingosine N-acyltransferase activity(GO:0050291) |
| 0.1 | 2.9 | GO:0030742 | GTP-dependent protein binding(GO:0030742) |
| 0.1 | 1.1 | GO:0004679 | AMP-activated protein kinase activity(GO:0004679) |
| 0.1 | 0.5 | GO:0008865 | glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158) |
| 0.1 | 3.6 | GO:0036002 | pre-mRNA binding(GO:0036002) |
| 0.1 | 22.6 | GO:0003924 | GTPase activity(GO:0003924) |
| 0.1 | 2.7 | GO:0048365 | Rac GTPase binding(GO:0048365) |
| 0.0 | 0.6 | GO:0016909 | JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909) |
| 0.0 | 1.5 | GO:0015269 | calcium-activated potassium channel activity(GO:0015269) |
| 0.0 | 0.4 | GO:0043533 | inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533) |
| 0.0 | 8.6 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
| 0.0 | 0.4 | GO:0061665 | SUMO ligase activity(GO:0061665) |
| 0.0 | 0.4 | GO:0071253 | connexin binding(GO:0071253) gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075) |
| 0.0 | 0.6 | GO:0097200 | cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200) |
| 0.0 | 1.1 | GO:0004859 | phospholipase inhibitor activity(GO:0004859) |
| 0.0 | 11.3 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 0.0 | 2.6 | GO:0004712 | protein serine/threonine/tyrosine kinase activity(GO:0004712) |
| 0.0 | 1.8 | GO:0035091 | phosphatidylinositol binding(GO:0035091) |
| 0.0 | 0.8 | GO:0004143 | diacylglycerol kinase activity(GO:0004143) |
| 0.0 | 1.6 | GO:0001221 | transcription cofactor binding(GO:0001221) |
| 0.0 | 19.6 | GO:0003779 | actin binding(GO:0003779) |
| 0.0 | 1.0 | GO:0008266 | poly-pyrimidine tract binding(GO:0008187) poly(U) RNA binding(GO:0008266) |
| 0.0 | 4.0 | GO:0031072 | heat shock protein binding(GO:0031072) |
| 0.0 | 1.2 | GO:0017091 | AU-rich element binding(GO:0017091) |
| 0.0 | 0.3 | GO:0015379 | potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820) |
| 0.0 | 0.7 | GO:0046933 | proton-transporting ATP synthase activity, rotational mechanism(GO:0046933) |
| 0.0 | 1.5 | GO:0008236 | serine-type peptidase activity(GO:0008236) |
| 0.0 | 1.7 | GO:0004402 | histone acetyltransferase activity(GO:0004402) |
| 0.0 | 1.1 | GO:0050699 | WW domain binding(GO:0050699) |
| 0.0 | 0.1 | GO:0004775 | succinate-CoA ligase (ADP-forming) activity(GO:0004775) |
| 0.0 | 2.5 | GO:0004843 | thiol-dependent ubiquitin-specific protease activity(GO:0004843) |
| 0.0 | 0.3 | GO:0008429 | phosphatidylethanolamine binding(GO:0008429) |
| 0.0 | 0.9 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
| 0.0 | 0.5 | GO:0050750 | low-density lipoprotein particle receptor binding(GO:0050750) |
| 0.0 | 1.0 | GO:0003743 | translation initiation factor activity(GO:0003743) |
| 0.0 | 0.3 | GO:0005041 | low-density lipoprotein receptor activity(GO:0005041) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.8 | 103.4 | PID RHOA REG PATHWAY | Regulation of RhoA activity |
| 0.8 | 34.5 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
| 0.8 | 16.3 | PID RANBP2 PATHWAY | Sumoylation by RanBP2 regulates transcriptional repression |
| 0.6 | 13.8 | PID INTEGRIN4 PATHWAY | Alpha6 beta4 integrin-ligand interactions |
| 0.5 | 55.4 | PID TAP63 PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 0.5 | 18.1 | PID ANTHRAX PATHWAY | Cellular roles of Anthrax toxin |
| 0.2 | 8.9 | SA B CELL RECEPTOR COMPLEXES | Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases. |
| 0.2 | 11.7 | PID TRAIL PATHWAY | TRAIL signaling pathway |
| 0.2 | 8.1 | PID WNT CANONICAL PATHWAY | Canonical Wnt signaling pathway |
| 0.2 | 17.6 | PID KIT PATHWAY | Signaling events mediated by Stem cell factor receptor (c-Kit) |
| 0.1 | 7.0 | PID AVB3 OPN PATHWAY | Osteopontin-mediated events |
| 0.1 | 8.1 | PID ALPHA SYNUCLEIN PATHWAY | Alpha-synuclein signaling |
| 0.1 | 14.0 | ST INTEGRIN SIGNALING PATHWAY | Integrin Signaling Pathway |
| 0.1 | 3.9 | PID GLYPICAN 1PATHWAY | Glypican 1 network |
| 0.1 | 2.9 | PID PI3KCI PATHWAY | Class I PI3K signaling events |
| 0.1 | 1.3 | PID EPHRINB REV PATHWAY | Ephrin B reverse signaling |
| 0.1 | 6.5 | PID MET PATHWAY | Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met) |
| 0.1 | 4.9 | PID TCR PATHWAY | TCR signaling in naïve CD4+ T cells |
| 0.1 | 20.8 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.0 | 4.2 | WNT SIGNALING | Genes related to Wnt-mediated signal transduction |
| 0.0 | 0.2 | SA PTEN PATHWAY | PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate. |
| 0.0 | 11.0 | NABA SECRETED FACTORS | Genes encoding secreted soluble factors |
| 0.0 | 0.7 | PID VEGFR1 2 PATHWAY | Signaling events mediated by VEGFR1 and VEGFR2 |
| 0.0 | 1.2 | PID P38 MK2 PATHWAY | p38 signaling mediated by MAPKAP kinases |
| 0.0 | 1.1 | PID LKB1 PATHWAY | LKB1 signaling events |
| 0.0 | 0.5 | PID HDAC CLASSII PATHWAY | Signaling events mediated by HDAC Class II |
| 0.0 | 0.6 | PID NCADHERIN PATHWAY | N-cadherin signaling events |
| 0.0 | 1.2 | PID ERA GENOMIC PATHWAY | Validated nuclear estrogen receptor alpha network |
| 0.0 | 1.5 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
| 0.0 | 0.7 | NABA BASEMENT MEMBRANES | Genes encoding structural components of basement membranes |
| 0.0 | 3.1 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.0 | 0.5 | ST JNK MAPK PATHWAY | JNK MAPK Pathway |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.2 | 39.8 | REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING | Genes involved in Advanced glycosylation endproduct receptor signaling |
| 1.1 | 18.1 | REACTOME THE NLRP3 INFLAMMASOME | Genes involved in The NLRP3 inflammasome |
| 0.6 | 16.3 | REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL | Genes involved in AKT phosphorylates targets in the cytosol |
| 0.6 | 13.9 | REACTOME GAP JUNCTION ASSEMBLY | Genes involved in Gap junction assembly |
| 0.5 | 14.7 | REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS | Genes involved in Facilitative Na+-independent glucose transporters |
| 0.3 | 9.0 | REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS | Genes involved in ABCA transporters in lipid homeostasis |
| 0.3 | 86.9 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
| 0.3 | 7.5 | REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
| 0.3 | 6.3 | REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE | Genes involved in Synthesis of PIPs at the early endosome membrane |
| 0.3 | 26.1 | REACTOME METABOLISM OF VITAMINS AND COFACTORS | Genes involved in Metabolism of vitamins and cofactors |
| 0.3 | 8.0 | REACTOME GLUCURONIDATION | Genes involved in Glucuronidation |
| 0.2 | 8.3 | REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS | Genes involved in Extrinsic Pathway for Apoptosis |
| 0.2 | 5.0 | REACTOME HYALURONAN UPTAKE AND DEGRADATION | Genes involved in Hyaluronan uptake and degradation |
| 0.2 | 3.2 | REACTOME ACYL CHAIN REMODELLING OF PS | Genes involved in Acyl chain remodelling of PS |
| 0.2 | 7.0 | REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS | Genes involved in Caspase-mediated cleavage of cytoskeletal proteins |
| 0.2 | 4.8 | REACTOME REGULATION OF SIGNALING BY CBL | Genes involved in Regulation of signaling by CBL |
| 0.2 | 10.0 | REACTOME ION TRANSPORT BY P TYPE ATPASES | Genes involved in Ion transport by P-type ATPases |
| 0.2 | 4.8 | REACTOME REGULATION OF KIT SIGNALING | Genes involved in Regulation of KIT signaling |
| 0.1 | 4.2 | REACTOME PROLACTIN RECEPTOR SIGNALING | Genes involved in Prolactin receptor signaling |
| 0.1 | 4.6 | REACTOME OTHER SEMAPHORIN INTERACTIONS | Genes involved in Other semaphorin interactions |
| 0.1 | 9.1 | REACTOME RECYCLING PATHWAY OF L1 | Genes involved in Recycling pathway of L1 |
| 0.1 | 2.4 | REACTOME PURINE CATABOLISM | Genes involved in Purine catabolism |
| 0.1 | 4.8 | REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION | Genes involved in GABA synthesis, release, reuptake and degradation |
| 0.1 | 2.7 | REACTOME ACTIVATION OF RAC | Genes involved in Activation of Rac |
| 0.1 | 2.2 | REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS | Genes involved in Activation of the AP-1 family of transcription factors |
| 0.1 | 1.2 | REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE | Genes involved in mRNA Decay by 3' to 5' Exoribonuclease |
| 0.1 | 14.1 | REACTOME CELL JUNCTION ORGANIZATION | Genes involved in Cell junction organization |
| 0.1 | 1.9 | REACTOME P2Y RECEPTORS | Genes involved in P2Y receptors |
| 0.1 | 2.4 | REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES | Genes involved in Cytosolic sulfonation of small molecules |
| 0.1 | 1.8 | REACTOME DCC MEDIATED ATTRACTIVE SIGNALING | Genes involved in DCC mediated attractive signaling |
| 0.1 | 6.7 | REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
| 0.1 | 1.6 | REACTOME METABOLISM OF PORPHYRINS | Genes involved in Metabolism of porphyrins |
| 0.1 | 1.1 | REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK | Genes involved in Regulation of Rheb GTPase activity by AMPK |
| 0.0 | 1.7 | REACTOME SIGNALING BY NODAL | Genes involved in Signaling by NODAL |
| 0.0 | 1.6 | REACTOME FORMATION OF INCISION COMPLEX IN GG NER | Genes involved in Formation of incision complex in GG-NER |
| 0.0 | 2.2 | REACTOME EFFECTS OF PIP2 HYDROLYSIS | Genes involved in Effects of PIP2 hydrolysis |
| 0.0 | 0.8 | REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE | Genes involved in mRNA Decay by 5' to 3' Exoribonuclease |
| 0.0 | 2.3 | REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING | Genes involved in Negative regulators of RIG-I/MDA5 signaling |
| 0.0 | 0.7 | REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING | Genes involved in Formation of ATP by chemiosmotic coupling |
| 0.0 | 0.4 | REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 | Genes involved in Signaling by activated point mutants of FGFR1 |
| 0.0 | 1.3 | REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
| 0.0 | 0.7 | REACTOME NETRIN1 SIGNALING | Genes involved in Netrin-1 signaling |
| 0.0 | 1.5 | REACTOME SMOOTH MUSCLE CONTRACTION | Genes involved in Smooth Muscle Contraction |
| 0.0 | 0.5 | REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS | Genes involved in Regulation of gene expression in beta cells |
| 0.0 | 0.5 | REACTOME SYNTHESIS OF PA | Genes involved in Synthesis of PA |
| 0.0 | 4.3 | REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |