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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for TP73

Z-value: 1.28

Motif logo

Transcription factors associated with TP73

Gene Symbol Gene ID Gene Info
ENSG00000078900.10 tumor protein p73

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TP73hg19_v2_chr1_+_3598871_35989300.233.3e-01Click!

Activity profile of TP73 motif

Sorted Z-values of TP73 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr14_+_75746340 5.40 ENST00000555686.1
ENST00000555672.1
FBJ murine osteosarcoma viral oncogene homolog
chr14_+_75745477 5.34 ENST00000303562.4
ENST00000554617.1
ENST00000554212.1
ENST00000535987.1
ENST00000555242.1
FBJ murine osteosarcoma viral oncogene homolog
chr3_+_136676707 3.95 ENST00000329582.4
interleukin 20 receptor beta
chr3_+_136676851 3.75 ENST00000309741.5
interleukin 20 receptor beta
chr15_+_41136216 2.92 ENST00000562057.1
ENST00000344051.4
serine peptidase inhibitor, Kunitz type 1
chr2_+_95940186 2.77 ENST00000403131.2
ENST00000317668.4
ENST00000317620.9
prominin 2
chr19_+_45281118 2.71 ENST00000270279.3
ENST00000341505.4
Cbl proto-oncogene C, E3 ubiquitin protein ligase
chr15_+_41136586 2.41 ENST00000431806.1
serine peptidase inhibitor, Kunitz type 1
chr3_-_185538849 2.25 ENST00000421047.2
insulin-like growth factor 2 mRNA binding protein 2
chr1_-_26197744 2.14 ENST00000374296.3
progestin and adipoQ receptor family member VII
chr2_+_95940220 2.14 ENST00000542147.1
prominin 2
chr3_-_50340996 2.13 ENST00000266031.4
ENST00000395143.2
ENST00000457214.2
ENST00000447605.2
ENST00000418723.1
ENST00000395144.2
hyaluronoglucosaminidase 1
chr17_+_73750699 2.06 ENST00000584939.1
integrin, beta 4
chr18_-_28681950 1.99 ENST00000251081.6
desmocollin 2
chr15_+_41136369 1.94 ENST00000563656.1
serine peptidase inhibitor, Kunitz type 1
chr10_-_47173994 1.79 ENST00000414655.2
ENST00000545298.1
ENST00000359178.4
ENST00000358140.4
ENST00000503031.1
annexin A8-like 1
long intergenic non-protein coding RNA 842
chr5_+_125758865 1.46 ENST00000542322.1
ENST00000544396.1
GRAM domain containing 3
chr5_+_125758813 1.42 ENST00000285689.3
ENST00000515200.1
GRAM domain containing 3
chr7_-_100171270 1.40 ENST00000538735.1
Sin3A-associated protein, 25kDa
chr6_-_112194484 1.38 ENST00000518295.1
ENST00000484067.2
ENST00000229470.5
ENST00000356013.2
ENST00000368678.4
ENST00000523238.1
ENST00000354650.3
FYN oncogene related to SRC, FGR, YES
chrX_-_80377162 1.26 ENST00000430960.1
ENST00000447319.1
high mobility group nucleosome binding domain 5
chr10_+_47746929 1.25 ENST00000340243.6
ENST00000374277.5
ENST00000449464.2
ENST00000538825.1
ENST00000335083.5
annexin A8-like 2
Protein LOC100996760
chr11_+_65686952 1.24 ENST00000527119.1
DR1-associated protein 1 (negative cofactor 2 alpha)
chr22_-_37976082 1.23 ENST00000215886.4
lectin, galactoside-binding, soluble, 2
chrX_-_80377118 1.22 ENST00000373250.3
high mobility group nucleosome binding domain 5
chr4_-_87770416 1.20 ENST00000273905.6
solute carrier family 10 (sodium/bile acid cotransporter), member 6
chr19_+_19627026 1.19 ENST00000608404.1
ENST00000555938.1
ENST00000503283.1
ENST00000512771.3
ENST00000428459.2
YjeF N-terminal domain containing 3
Uncharacterized protein
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13
chr15_+_41136263 1.10 ENST00000568823.1
serine peptidase inhibitor, Kunitz type 1
chrX_+_9880412 1.03 ENST00000418909.2
shroom family member 2
chr12_-_82752565 0.96 ENST00000256151.7
coiled-coil domain containing 59
chr1_-_68698222 0.96 ENST00000370976.3
ENST00000354777.2
ENST00000262348.4
ENST00000540432.1
wntless Wnt ligand secretion mediator
chr3_+_42201653 0.93 ENST00000341421.3
ENST00000396175.1
trafficking protein, kinesin binding 1
chr14_+_105190514 0.91 ENST00000330877.2
adenylosuccinate synthase like 1
chr1_+_155146318 0.89 ENST00000368385.4
ENST00000545012.1
ENST00000392451.2
ENST00000368383.3
ENST00000368382.1
ENST00000334634.4
tripartite motif containing 46
chr5_+_125759140 0.87 ENST00000543198.1
GRAM domain containing 3
chr16_+_84178874 0.84 ENST00000378553.5
dynein, axonemal, assembly factor 1
chr16_+_67197288 0.83 ENST00000264009.8
ENST00000421453.1
heat shock transcription factor 4
chr18_+_77623668 0.82 ENST00000316249.3
potassium voltage-gated channel, subfamily G, member 2
chr14_-_36983034 0.82 ENST00000518529.2
surfactant associated 3
chr13_-_48877795 0.81 ENST00000436963.1
ENST00000433480.2
long intergenic non-protein coding RNA 441
chr1_-_78444738 0.81 ENST00000436586.2
ENST00000370768.2
far upstream element (FUSE) binding protein 1
chr9_-_128003606 0.78 ENST00000324460.6
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
chr1_-_78444776 0.76 ENST00000370767.1
ENST00000421641.1
far upstream element (FUSE) binding protein 1
chr18_-_53253323 0.70 ENST00000540999.1
ENST00000563888.2
transcription factor 4
chr19_+_41856816 0.67 ENST00000539627.1
transmembrane protein 91
chr14_-_105531759 0.67 ENST00000329797.3
ENST00000539291.2
ENST00000392585.2
G protein-coupled receptor 132
chr8_+_145065705 0.66 ENST00000533044.1
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
chr6_+_31515337 0.66 ENST00000376148.4
ENST00000376145.4
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
chr6_-_46703069 0.65 ENST00000538237.1
ENST00000274793.7
phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
chr16_+_84178850 0.65 ENST00000334315.5
dynein, axonemal, assembly factor 1
chr17_-_79818354 0.65 ENST00000576541.1
ENST00000576380.1
ENST00000571617.1
ENST00000576052.1
ENST00000576390.1
ENST00000573778.2
ENST00000439918.2
ENST00000574914.1
ENST00000331483.4
prolyl 4-hydroxylase, beta polypeptide
chr9_+_6758024 0.64 ENST00000442236.2
lysine (K)-specific demethylase 4C
chr11_+_236959 0.61 ENST00000431206.2
ENST00000528906.1
proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
chr16_-_8891481 0.60 ENST00000333050.6
transmembrane protein 186
chr11_+_65687158 0.60 ENST00000532933.1
DR1-associated protein 1 (negative cofactor 2 alpha)
chr9_+_6757634 0.58 ENST00000543771.1
ENST00000401787.3
ENST00000381306.3
ENST00000381309.3
lysine (K)-specific demethylase 4C
chr10_-_99185798 0.56 ENST00000439965.2
LOC644215 protein; Uncharacterized protein
chr2_-_232328867 0.56 ENST00000453992.1
ENST00000417652.1
ENST00000454824.1
nucleolin
chr5_+_38258511 0.54 ENST00000354891.3
ENST00000322350.5
EGF-like, fibronectin type III and laminin G domains
chr18_-_53253112 0.54 ENST00000568673.1
ENST00000562847.1
ENST00000568147.1
transcription factor 4
chr8_+_145065521 0.52 ENST00000534791.1
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
chr16_+_222846 0.50 ENST00000251595.6
ENST00000397806.1
hemoglobin, alpha 2
chrX_+_9880590 0.48 ENST00000452575.1
shroom family member 2
chr12_+_113495492 0.48 ENST00000257600.3
deltex homolog 1 (Drosophila)
chr3_+_48481658 0.46 ENST00000438607.2
translation machinery associated 7 homolog (S. cerevisiae)
chr11_+_236540 0.46 ENST00000532097.1
proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
chr11_-_65686496 0.44 ENST00000449692.3
chromosome 11 open reading frame 68
chr15_-_74043816 0.43 ENST00000379822.4
chromosome 15 open reading frame 59
chr1_-_68698197 0.43 ENST00000370973.2
ENST00000370971.1
wntless Wnt ligand secretion mediator
chr22_+_39966758 0.41 ENST00000407673.1
ENST00000401624.1
ENST00000404898.1
ENST00000402142.3
ENST00000336649.4
ENST00000400164.3
calcium channel, voltage-dependent, T type, alpha 1I subunit
chr1_-_214724566 0.40 ENST00000366956.5
protein tyrosine phosphatase, non-receptor type 14
chr8_-_70745575 0.38 ENST00000524945.1
solute carrier organic anion transporter family, member 5A1
chr10_-_91295304 0.38 ENST00000341233.4
ENST00000371790.4
solute carrier family 16, member 12
chr12_-_57505121 0.37 ENST00000538913.2
ENST00000537215.2
ENST00000454075.3
ENST00000554825.1
ENST00000553275.1
ENST00000300134.3
signal transducer and activator of transcription 6, interleukin-4 induced
chr18_-_4455260 0.37 ENST00000581527.1
discs, large (Drosophila) homolog-associated protein 1
chr1_-_52344471 0.37 ENST00000352171.7
ENST00000354831.7
nardilysin (N-arginine dibasic convertase)
chr12_-_56881874 0.31 ENST00000539272.1
glutaminase 2 (liver, mitochondrial)
chr17_-_80059726 0.31 ENST00000583053.1
coiled-coil domain containing 57
chr16_-_1146244 0.30 ENST00000328449.5
C1q and tumor necrosis factor related protein 8
chr2_-_98972468 0.30 ENST00000454230.1
Uncharacterized protein
chr16_+_5008290 0.29 ENST00000251170.7
SEC14-like 5 (S. cerevisiae)
chr18_-_53253000 0.29 ENST00000566514.1
transcription factor 4
chr12_+_96196875 0.28 ENST00000553095.1
Uncharacterized protein
chr6_-_122792919 0.28 ENST00000339697.4
serine incorporator 1
chr20_+_35504522 0.27 ENST00000602922.1
ENST00000217320.3
TBC/LysM-associated domain containing 2
chr11_+_237016 0.27 ENST00000352303.5
proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
chr6_-_46703430 0.27 ENST00000537365.1
phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
chr2_-_26864228 0.26 ENST00000288861.4
calcium and integrin binding family member 4
chr5_+_78532003 0.25 ENST00000396137.4
junction mediating and regulatory protein, p53 cofactor
chr3_-_151160938 0.23 ENST00000489791.1
immunoglobulin superfamily, member 10
chr12_-_117319236 0.22 ENST00000257572.5
harakiri, BCL2 interacting protein (contains only BH3 domain)
chr21_+_43442100 0.21 ENST00000455701.1
ENST00000596595.1
ZNF295 antisense RNA 1
chr9_+_6758109 0.19 ENST00000536108.1
lysine (K)-specific demethylase 4C
chr19_-_39226045 0.17 ENST00000597987.1
ENST00000595177.1
calpain 12
chr8_+_120885949 0.17 ENST00000523492.1
ENST00000286234.5
DEP domain containing MTOR-interacting protein
chr9_+_131445703 0.16 ENST00000454747.1
SET nuclear oncogene
chr9_-_130517309 0.16 ENST00000414380.1
SH2 domain containing 3C
chr5_-_135528822 0.15 ENST00000607574.1
AC009014.3
chr12_+_31079362 0.15 ENST00000545802.1
tetraspanin 11
chr12_-_82752159 0.14 ENST00000552377.1
coiled-coil domain containing 59
chr17_-_2614927 0.14 ENST00000435359.1
clustered mitochondria (cluA/CLU1) homolog
chr9_+_87285257 0.14 ENST00000323115.4
neurotrophic tyrosine kinase, receptor, type 2
chr7_-_128045984 0.13 ENST00000470772.1
ENST00000480861.1
ENST00000496200.1
IMP (inosine 5'-monophosphate) dehydrogenase 1
chr10_+_70661014 0.13 ENST00000373585.3
DEAD (Asp-Glu-Ala-Asp) box polypeptide 50
chr12_+_82752647 0.12 ENST00000550058.1
methyltransferase like 25
chr7_-_100493482 0.12 ENST00000411582.1
ENST00000419336.2
ENST00000241069.5
ENST00000302913.4
acetylcholinesterase (Yt blood group)
chr12_+_82752275 0.12 ENST00000248306.3
methyltransferase like 25
chr5_+_119799927 0.12 ENST00000407149.2
ENST00000379551.2
proline rich 16
chr14_+_103566665 0.11 ENST00000559116.1
exocyst complex component 3-like 4
chr1_-_203055129 0.10 ENST00000241651.4
myogenin (myogenic factor 4)
chr11_-_31833719 0.10 ENST00000524853.1
paired box 6
chr9_+_36169380 0.09 ENST00000335119.2
calicin
chr11_+_75479850 0.09 ENST00000376262.3
ENST00000604733.1
diacylglycerol O-acyltransferase 2
chr16_+_75032901 0.08 ENST00000335325.4
ENST00000320619.6
zinc and ring finger 1, E3 ubiquitin protein ligase
chr17_-_39459103 0.07 ENST00000391353.1
keratin associated protein 29-1
chr1_-_235324530 0.07 ENST00000447801.1
ENST00000366606.3
ENST00000429912.1
RNA binding motif protein 34
chr17_-_40835076 0.07 ENST00000591765.1
chemokine (C-C motif) receptor 10
chr16_-_84178728 0.07 ENST00000562224.1
ENST00000434463.3
ENST00000564998.1
ENST00000219439.4
hydroxysteroid dehydrogenase like 1
chr12_-_56881909 0.07 ENST00000461077.1
glutaminase 2 (liver, mitochondrial)
chr10_-_97200772 0.07 ENST00000371241.1
ENST00000354106.3
ENST00000371239.1
ENST00000361941.3
ENST00000277982.5
ENST00000371245.3
sorbin and SH3 domain containing 1
chr12_+_82752283 0.07 ENST00000548200.1
methyltransferase like 25
chr15_+_57891609 0.06 ENST00000569089.1
myocardial zonula adherens protein
chr16_+_67195592 0.06 ENST00000519378.1
F-box and leucine-rich repeat protein 8
chrX_-_138724677 0.05 ENST00000370573.4
ENST00000338585.6
ENST00000370576.4
MCF.2 cell line derived transforming sequence
chr1_-_220220000 0.04 ENST00000366923.3
glutamyl-prolyl-tRNA synthetase
chr2_+_128293323 0.04 ENST00000389524.4
ENST00000428314.1
myosin VIIB
chr2_-_158485387 0.03 ENST00000243349.8
activin A receptor, type IC
chr1_+_47137544 0.03 ENST00000564373.1
testis expressed 38
chr10_-_79686284 0.03 ENST00000372391.2
ENST00000372388.2
discs, large homolog 5 (Drosophila)
chr6_+_155538093 0.02 ENST00000462408.2
T-cell lymphoma invasion and metastasis 2
chr16_-_2581409 0.02 ENST00000567119.1
ENST00000565480.1
ENST00000382350.1
cementum protein 1
chr19_-_35981358 0.02 ENST00000484218.2
ENST00000338897.3
keratinocyte differentiation-associated protein
chr17_-_28661065 0.01 ENST00000328886.4
ENST00000538566.2
transmembrane and immunoglobulin domain containing 1
chr17_+_37356555 0.01 ENST00000579374.1
ribosomal protein L19
chr14_+_52780998 0.00 ENST00000557436.1
prostaglandin E receptor 2 (subtype EP2), 53kDa
chr11_+_65154070 0.00 ENST00000317568.5
ENST00000531296.1
ENST00000533782.1
ENST00000355991.5
ENST00000416776.2
ENST00000526201.1
FERM domain containing 8
chrX_-_138724994 0.00 ENST00000536274.1
MCF.2 cell line derived transforming sequence

Network of associatons between targets according to the STRING database.

First level regulatory network of TP73

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 7.7 GO:0001808 negative regulation of type IV hypersensitivity(GO:0001808)
1.2 4.9 GO:2001287 negative regulation of caveolin-mediated endocytosis(GO:2001287)
1.2 10.7 GO:0001661 conditioned taste aversion(GO:0001661)
0.5 1.5 GO:0008057 eye pigment granule organization(GO:0008057)
0.4 2.1 GO:1900106 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.3 1.4 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.3 8.4 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.3 0.8 GO:0021577 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
0.2 0.9 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.2 2.0 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.2 1.5 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.1 0.9 GO:0046469 plasma lipoprotein particle oxidation(GO:0034441) platelet activating factor metabolic process(GO:0046469)
0.1 1.4 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.1 0.4 GO:0015881 creatine transport(GO:0015881) creatine transmembrane transport(GO:1902598)
0.1 2.1 GO:0035878 nail development(GO:0035878)
0.1 1.2 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.1 2.7 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.1 1.4 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.1 1.3 GO:0043248 proteasome assembly(GO:0043248)
0.1 0.4 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.1 0.9 GO:0099612 protein localization to axon(GO:0099612)
0.1 0.9 GO:0019896 axonal transport of mitochondrion(GO:0019896)
0.1 0.4 GO:0006543 glutamine catabolic process(GO:0006543)
0.0 0.6 GO:0034378 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) chylomicron assembly(GO:0034378) positive regulation of viral entry into host cell(GO:0046598)
0.0 0.6 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.0 0.3 GO:1904222 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.0 1.8 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.0 0.1 GO:0032223 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.0 0.8 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.3 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 1.2 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.0 0.7 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0 0.1 GO:0014735 regulation of muscle atrophy(GO:0014735) response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.0 0.1 GO:0099538 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551)
0.0 1.2 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.1 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.1 GO:0071400 cellular response to oleic acid(GO:0071400)
0.0 0.1 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.4 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 2.1 GO:0048477 oogenesis(GO:0048477)
0.0 0.4 GO:0001946 lymphangiogenesis(GO:0001946)
0.0 0.4 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.2 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 0.1 GO:0003322 pancreatic A cell development(GO:0003322)
0.0 0.0 GO:1901383 negative regulation of chorionic trophoblast cell proliferation(GO:1901383)
0.0 0.4 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 10.7 GO:0035976 AP1 complex(GO:0035976)
1.0 4.9 GO:0044393 microspike(GO:0044393)
0.7 2.1 GO:0036117 hyaluranon cable(GO:0036117)
0.2 0.6 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.1 0.9 GO:1990769 proximal neuron projection(GO:1990769)
0.1 1.3 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 1.9 GO:0030056 hemidesmosome(GO:0030056)
0.0 2.0 GO:0030057 desmosome(GO:0030057)
0.0 0.8 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 1.4 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.1 GO:0033011 perinuclear theca(GO:0033011)
0.0 0.9 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.8 GO:0042599 lamellar body(GO:0042599)
0.0 1.4 GO:0032590 dendrite membrane(GO:0032590)
0.0 0.5 GO:0005614 interstitial matrix(GO:0005614)
0.0 1.2 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.8 GO:1904115 axon cytoplasm(GO:1904115)
0.0 1.6 GO:0030864 cortical actin cytoskeleton(GO:0030864)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 7.7 GO:0042015 interleukin-20 binding(GO:0042015)
0.4 2.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.4 1.2 GO:0052857 NADHX epimerase activity(GO:0052856) NADPHX epimerase activity(GO:0052857)
0.3 0.9 GO:0004019 adenylosuccinate synthase activity(GO:0004019)
0.2 1.2 GO:0016936 galactoside binding(GO:0016936)
0.2 1.2 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.2 2.0 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.2 1.4 GO:0042610 CD8 receptor binding(GO:0042610)
0.1 2.1 GO:0038132 neuregulin binding(GO:0038132)
0.1 10.8 GO:0070412 R-SMAD binding(GO:0070412)
0.1 0.4 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.1 0.4 GO:0005308 creatine transmembrane transporter activity(GO:0005308)
0.1 0.9 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.1 1.5 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.1 1.4 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.1 1.5 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 1.4 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 0.6 GO:0019798 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.1 0.6 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.1 4.9 GO:0015485 cholesterol binding(GO:0015485)
0.1 8.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 2.2 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.4 GO:0004359 glutaminase activity(GO:0004359)
0.0 2.5 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 2.7 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.9 GO:0050811 GABA receptor binding(GO:0050811)
0.0 1.5 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.1 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.0 0.8 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.1 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 0.8 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.1 GO:0060175 brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.0 2.1 GO:0005496 steroid binding(GO:0005496)
0.0 0.1 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.0 0.3 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 1.8 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.3 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.5 GO:0005112 Notch binding(GO:0005112)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 10.7 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 2.1 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 1.4 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 2.9 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.9 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 4.1 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.4 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 10.0 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 2.1 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 1.4 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.1 1.2 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 0.8 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 1.9 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 1.0 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.9 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.6 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 1.6 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.5 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 1.3 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 1.2 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.8 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 1.9 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 0.4 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)