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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for TP73

Z-value: 1.28

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Transcription factors associated with TP73

Gene Symbol Gene ID Gene Info
TP73
ENSG00000078900.10 tumor protein p73

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TP73hg19_v2_chr1_+_3598871_35989300.233.3e-01Click!

Activity profile of TP73 motif

Sorted Z-values of TP73 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr14_+_75746340 5.40 ENST00000555686.1
ENST00000555672.1
FOS
FBJ murine osteosarcoma viral oncogene homolog
chr14_+_75745477 5.34 ENST00000303562.4
ENST00000554617.1
ENST00000554212.1
ENST00000535987.1
ENST00000555242.1
FOS
FBJ murine osteosarcoma viral oncogene homolog
chr3_+_136676707 3.95 ENST00000329582.4
IL20RB
interleukin 20 receptor beta
chr3_+_136676851 3.75 ENST00000309741.5
IL20RB
interleukin 20 receptor beta
chr15_+_41136216 2.92 ENST00000562057.1
ENST00000344051.4
SPINT1
serine peptidase inhibitor, Kunitz type 1
chr2_+_95940186 2.77 ENST00000403131.2
ENST00000317668.4
ENST00000317620.9
PROM2
prominin 2
chr19_+_45281118 2.71 ENST00000270279.3
ENST00000341505.4
CBLC
Cbl proto-oncogene C, E3 ubiquitin protein ligase
chr15_+_41136586 2.41 ENST00000431806.1
SPINT1
serine peptidase inhibitor, Kunitz type 1
chr3_-_185538849 2.25 ENST00000421047.2
IGF2BP2
insulin-like growth factor 2 mRNA binding protein 2
chr1_-_26197744 2.14 ENST00000374296.3
PAQR7
progestin and adipoQ receptor family member VII
chr2_+_95940220 2.14 ENST00000542147.1
PROM2
prominin 2
chr3_-_50340996 2.13 ENST00000266031.4
ENST00000395143.2
ENST00000457214.2
ENST00000447605.2
ENST00000418723.1
ENST00000395144.2
HYAL1
hyaluronoglucosaminidase 1
chr17_+_73750699 2.06 ENST00000584939.1
ITGB4
integrin, beta 4
chr18_-_28681950 1.99 ENST00000251081.6
DSC2
desmocollin 2
chr15_+_41136369 1.94 ENST00000563656.1
SPINT1
serine peptidase inhibitor, Kunitz type 1
chr10_-_47173994 1.79 ENST00000414655.2
ENST00000545298.1
ENST00000359178.4
ENST00000358140.4
ENST00000503031.1
ANXA8L1
LINC00842
annexin A8-like 1
long intergenic non-protein coding RNA 842
chr5_+_125758865 1.46 ENST00000542322.1
ENST00000544396.1
GRAMD3
GRAM domain containing 3
chr5_+_125758813 1.42 ENST00000285689.3
ENST00000515200.1
GRAMD3
GRAM domain containing 3
chr7_-_100171270 1.40 ENST00000538735.1
SAP25
Sin3A-associated protein, 25kDa
chr6_-_112194484 1.38 ENST00000518295.1
ENST00000484067.2
ENST00000229470.5
ENST00000356013.2
ENST00000368678.4
ENST00000523238.1
ENST00000354650.3
FYN
FYN oncogene related to SRC, FGR, YES
chrX_-_80377162 1.26 ENST00000430960.1
ENST00000447319.1
HMGN5
high mobility group nucleosome binding domain 5
chr10_+_47746929 1.25 ENST00000340243.6
ENST00000374277.5
ENST00000449464.2
ENST00000538825.1
ENST00000335083.5
ANXA8L2
AL603965.1
annexin A8-like 2
Protein LOC100996760
chr11_+_65686952 1.24 ENST00000527119.1
DRAP1
DR1-associated protein 1 (negative cofactor 2 alpha)
chr22_-_37976082 1.23 ENST00000215886.4
LGALS2
lectin, galactoside-binding, soluble, 2
chrX_-_80377118 1.22 ENST00000373250.3
HMGN5
high mobility group nucleosome binding domain 5
chr4_-_87770416 1.20 ENST00000273905.6
SLC10A6
solute carrier family 10 (sodium/bile acid cotransporter), member 6
chr19_+_19627026 1.19 ENST00000608404.1
ENST00000555938.1
ENST00000503283.1
ENST00000512771.3
ENST00000428459.2
YJEFN3
CTC-260F20.3
NDUFA13
YjeF N-terminal domain containing 3
Uncharacterized protein
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13
chr15_+_41136263 1.10 ENST00000568823.1
SPINT1
serine peptidase inhibitor, Kunitz type 1
chrX_+_9880412 1.03 ENST00000418909.2
SHROOM2
shroom family member 2
chr12_-_82752565 0.96 ENST00000256151.7
CCDC59
coiled-coil domain containing 59
chr1_-_68698222 0.96 ENST00000370976.3
ENST00000354777.2
ENST00000262348.4
ENST00000540432.1
WLS
wntless Wnt ligand secretion mediator
chr3_+_42201653 0.93 ENST00000341421.3
ENST00000396175.1
TRAK1
trafficking protein, kinesin binding 1
chr14_+_105190514 0.91 ENST00000330877.2
ADSSL1
adenylosuccinate synthase like 1
chr1_+_155146318 0.89 ENST00000368385.4
ENST00000545012.1
ENST00000392451.2
ENST00000368383.3
ENST00000368382.1
ENST00000334634.4
TRIM46
tripartite motif containing 46
chr5_+_125759140 0.87 ENST00000543198.1
GRAMD3
GRAM domain containing 3
chr16_+_84178874 0.84 ENST00000378553.5
DNAAF1
dynein, axonemal, assembly factor 1
chr16_+_67197288 0.83 ENST00000264009.8
ENST00000421453.1
HSF4
heat shock transcription factor 4
chr18_+_77623668 0.82 ENST00000316249.3
KCNG2
potassium voltage-gated channel, subfamily G, member 2
chr14_-_36983034 0.82 ENST00000518529.2
SFTA3
surfactant associated 3
chr13_-_48877795 0.81 ENST00000436963.1
ENST00000433480.2
LINC00441
long intergenic non-protein coding RNA 441
chr1_-_78444738 0.81 ENST00000436586.2
ENST00000370768.2
FUBP1
far upstream element (FUSE) binding protein 1
chr9_-_128003606 0.78 ENST00000324460.6
HSPA5
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
chr1_-_78444776 0.76 ENST00000370767.1
ENST00000421641.1
FUBP1
far upstream element (FUSE) binding protein 1
chr18_-_53253323 0.70 ENST00000540999.1
ENST00000563888.2
TCF4
transcription factor 4
chr19_+_41856816 0.67 ENST00000539627.1
TMEM91
transmembrane protein 91
chr14_-_105531759 0.67 ENST00000329797.3
ENST00000539291.2
ENST00000392585.2
GPR132
G protein-coupled receptor 132
chr8_+_145065705 0.66 ENST00000533044.1
GRINA
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
chr6_+_31515337 0.66 ENST00000376148.4
ENST00000376145.4
NFKBIL1
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
chr6_-_46703069 0.65 ENST00000538237.1
ENST00000274793.7
PLA2G7
phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
chr16_+_84178850 0.65 ENST00000334315.5
DNAAF1
dynein, axonemal, assembly factor 1
chr17_-_79818354 0.65 ENST00000576541.1
ENST00000576380.1
ENST00000571617.1
ENST00000576052.1
ENST00000576390.1
ENST00000573778.2
ENST00000439918.2
ENST00000574914.1
ENST00000331483.4
P4HB
prolyl 4-hydroxylase, beta polypeptide
chr9_+_6758024 0.64 ENST00000442236.2
KDM4C
lysine (K)-specific demethylase 4C
chr11_+_236959 0.61 ENST00000431206.2
ENST00000528906.1
PSMD13
proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
chr16_-_8891481 0.60 ENST00000333050.6
TMEM186
transmembrane protein 186
chr11_+_65687158 0.60 ENST00000532933.1
DRAP1
DR1-associated protein 1 (negative cofactor 2 alpha)
chr9_+_6757634 0.58 ENST00000543771.1
ENST00000401787.3
ENST00000381306.3
ENST00000381309.3
KDM4C
lysine (K)-specific demethylase 4C
chr10_-_99185798 0.56 ENST00000439965.2
AL355490.1
LOC644215 protein; Uncharacterized protein
chr2_-_232328867 0.56 ENST00000453992.1
ENST00000417652.1
ENST00000454824.1
NCL
nucleolin
chr5_+_38258511 0.54 ENST00000354891.3
ENST00000322350.5
EGFLAM
EGF-like, fibronectin type III and laminin G domains
chr18_-_53253112 0.54 ENST00000568673.1
ENST00000562847.1
ENST00000568147.1
TCF4
transcription factor 4
chr8_+_145065521 0.52 ENST00000534791.1
GRINA
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
chr16_+_222846 0.50 ENST00000251595.6
ENST00000397806.1
HBA2
hemoglobin, alpha 2
chrX_+_9880590 0.48 ENST00000452575.1
SHROOM2
shroom family member 2
chr12_+_113495492 0.48 ENST00000257600.3
DTX1
deltex homolog 1 (Drosophila)
chr3_+_48481658 0.46 ENST00000438607.2
TMA7
translation machinery associated 7 homolog (S. cerevisiae)
chr11_+_236540 0.46 ENST00000532097.1
PSMD13
proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
chr11_-_65686496 0.44 ENST00000449692.3
C11orf68
chromosome 11 open reading frame 68
chr15_-_74043816 0.43 ENST00000379822.4
C15orf59
chromosome 15 open reading frame 59
chr1_-_68698197 0.43 ENST00000370973.2
ENST00000370971.1
WLS
wntless Wnt ligand secretion mediator
chr22_+_39966758 0.41 ENST00000407673.1
ENST00000401624.1
ENST00000404898.1
ENST00000402142.3
ENST00000336649.4
ENST00000400164.3
CACNA1I
calcium channel, voltage-dependent, T type, alpha 1I subunit
chr1_-_214724566 0.40 ENST00000366956.5
PTPN14
protein tyrosine phosphatase, non-receptor type 14
chr8_-_70745575 0.38 ENST00000524945.1
SLCO5A1
solute carrier organic anion transporter family, member 5A1
chr10_-_91295304 0.38 ENST00000341233.4
ENST00000371790.4
SLC16A12
solute carrier family 16, member 12
chr12_-_57505121 0.37 ENST00000538913.2
ENST00000537215.2
ENST00000454075.3
ENST00000554825.1
ENST00000553275.1
ENST00000300134.3
STAT6
signal transducer and activator of transcription 6, interleukin-4 induced
chr18_-_4455260 0.37 ENST00000581527.1
DLGAP1
discs, large (Drosophila) homolog-associated protein 1
chr1_-_52344471 0.37 ENST00000352171.7
ENST00000354831.7
NRD1
nardilysin (N-arginine dibasic convertase)
chr12_-_56881874 0.31 ENST00000539272.1
GLS2
glutaminase 2 (liver, mitochondrial)
chr17_-_80059726 0.31 ENST00000583053.1
CCDC57
coiled-coil domain containing 57
chr16_-_1146244 0.30 ENST00000328449.5
C1QTNF8
C1q and tumor necrosis factor related protein 8
chr2_-_98972468 0.30 ENST00000454230.1
AC092675.3
Uncharacterized protein
chr16_+_5008290 0.29 ENST00000251170.7
SEC14L5
SEC14-like 5 (S. cerevisiae)
chr18_-_53253000 0.29 ENST00000566514.1
TCF4
transcription factor 4
chr12_+_96196875 0.28 ENST00000553095.1
RP11-536G4.1
Uncharacterized protein
chr6_-_122792919 0.28 ENST00000339697.4
SERINC1
serine incorporator 1
chr20_+_35504522 0.27 ENST00000602922.1
ENST00000217320.3
TLDC2
TBC/LysM-associated domain containing 2
chr11_+_237016 0.27 ENST00000352303.5
PSMD13
proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
chr6_-_46703430 0.27 ENST00000537365.1
PLA2G7
phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
chr2_-_26864228 0.26 ENST00000288861.4
CIB4
calcium and integrin binding family member 4
chr5_+_78532003 0.25 ENST00000396137.4
JMY
junction mediating and regulatory protein, p53 cofactor
chr3_-_151160938 0.23 ENST00000489791.1
IGSF10
immunoglobulin superfamily, member 10
chr12_-_117319236 0.22 ENST00000257572.5
HRK
harakiri, BCL2 interacting protein (contains only BH3 domain)
chr21_+_43442100 0.21 ENST00000455701.1
ENST00000596595.1
ZNF295-AS1
ZNF295 antisense RNA 1
chr9_+_6758109 0.19 ENST00000536108.1
KDM4C
lysine (K)-specific demethylase 4C
chr19_-_39226045 0.17 ENST00000597987.1
ENST00000595177.1
CAPN12
calpain 12
chr8_+_120885949 0.17 ENST00000523492.1
ENST00000286234.5
DEPTOR
DEP domain containing MTOR-interacting protein
chr9_+_131445703 0.16 ENST00000454747.1
SET
SET nuclear oncogene
chr9_-_130517309 0.16 ENST00000414380.1
SH2D3C
SH2 domain containing 3C
chr5_-_135528822 0.15 ENST00000607574.1
AC009014.3
AC009014.3
chr12_+_31079362 0.15 ENST00000545802.1
TSPAN11
tetraspanin 11
chr12_-_82752159 0.14 ENST00000552377.1
CCDC59
coiled-coil domain containing 59
chr17_-_2614927 0.14 ENST00000435359.1
CLUH
clustered mitochondria (cluA/CLU1) homolog
chr9_+_87285257 0.14 ENST00000323115.4
NTRK2
neurotrophic tyrosine kinase, receptor, type 2
chr7_-_128045984 0.13 ENST00000470772.1
ENST00000480861.1
ENST00000496200.1
IMPDH1
IMP (inosine 5'-monophosphate) dehydrogenase 1
chr10_+_70661014 0.13 ENST00000373585.3
DDX50
DEAD (Asp-Glu-Ala-Asp) box polypeptide 50
chr12_+_82752647 0.12 ENST00000550058.1
METTL25
methyltransferase like 25
chr7_-_100493482 0.12 ENST00000411582.1
ENST00000419336.2
ENST00000241069.5
ENST00000302913.4
ACHE
acetylcholinesterase (Yt blood group)
chr12_+_82752275 0.12 ENST00000248306.3
METTL25
methyltransferase like 25
chr5_+_119799927 0.12 ENST00000407149.2
ENST00000379551.2
PRR16
proline rich 16
chr14_+_103566665 0.11 ENST00000559116.1
EXOC3L4
exocyst complex component 3-like 4
chr1_-_203055129 0.10 ENST00000241651.4
MYOG
myogenin (myogenic factor 4)
chr11_-_31833719 0.10 ENST00000524853.1
PAX6
paired box 6
chr9_+_36169380 0.09 ENST00000335119.2
CCIN
calicin
chr11_+_75479850 0.09 ENST00000376262.3
ENST00000604733.1
DGAT2
diacylglycerol O-acyltransferase 2
chr16_+_75032901 0.08 ENST00000335325.4
ENST00000320619.6
ZNRF1
zinc and ring finger 1, E3 ubiquitin protein ligase
chr17_-_39459103 0.07 ENST00000391353.1
KRTAP29-1
keratin associated protein 29-1
chr1_-_235324530 0.07 ENST00000447801.1
ENST00000366606.3
ENST00000429912.1
RBM34
RNA binding motif protein 34
chr17_-_40835076 0.07 ENST00000591765.1
CCR10
chemokine (C-C motif) receptor 10
chr16_-_84178728 0.07 ENST00000562224.1
ENST00000434463.3
ENST00000564998.1
ENST00000219439.4
HSDL1
hydroxysteroid dehydrogenase like 1
chr12_-_56881909 0.07 ENST00000461077.1
GLS2
glutaminase 2 (liver, mitochondrial)
chr10_-_97200772 0.07 ENST00000371241.1
ENST00000354106.3
ENST00000371239.1
ENST00000361941.3
ENST00000277982.5
ENST00000371245.3
SORBS1
sorbin and SH3 domain containing 1
chr12_+_82752283 0.07 ENST00000548200.1
METTL25
methyltransferase like 25
chr15_+_57891609 0.06 ENST00000569089.1
MYZAP
myocardial zonula adherens protein
chr16_+_67195592 0.06 ENST00000519378.1
FBXL8
F-box and leucine-rich repeat protein 8
chrX_-_138724677 0.05 ENST00000370573.4
ENST00000338585.6
ENST00000370576.4
MCF2
MCF.2 cell line derived transforming sequence
chr1_-_220220000 0.04 ENST00000366923.3
EPRS
glutamyl-prolyl-tRNA synthetase
chr2_+_128293323 0.04 ENST00000389524.4
ENST00000428314.1
MYO7B
myosin VIIB
chr2_-_158485387 0.03 ENST00000243349.8
ACVR1C
activin A receptor, type IC
chr1_+_47137544 0.03 ENST00000564373.1
TEX38
testis expressed 38
chr10_-_79686284 0.03 ENST00000372391.2
ENST00000372388.2
DLG5
discs, large homolog 5 (Drosophila)
chr6_+_155538093 0.02 ENST00000462408.2
TIAM2
T-cell lymphoma invasion and metastasis 2
chr16_-_2581409 0.02 ENST00000567119.1
ENST00000565480.1
ENST00000382350.1
CEMP1
cementum protein 1
chr19_-_35981358 0.02 ENST00000484218.2
ENST00000338897.3
KRTDAP
keratinocyte differentiation-associated protein
chr17_-_28661065 0.01 ENST00000328886.4
ENST00000538566.2
TMIGD1
transmembrane and immunoglobulin domain containing 1
chr17_+_37356555 0.01 ENST00000579374.1
RPL19
ribosomal protein L19
chr14_+_52780998 0.00 ENST00000557436.1
PTGER2
prostaglandin E receptor 2 (subtype EP2), 53kDa
chr11_+_65154070 0.00 ENST00000317568.5
ENST00000531296.1
ENST00000533782.1
ENST00000355991.5
ENST00000416776.2
ENST00000526201.1
FRMD8
FERM domain containing 8
chrX_-_138724994 0.00 ENST00000536274.1
MCF2
MCF.2 cell line derived transforming sequence

Network of associatons between targets according to the STRING database.

First level regulatory network of TP73

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 7.7 GO:0001808 negative regulation of type IV hypersensitivity(GO:0001808)
1.2 4.9 GO:2001287 negative regulation of caveolin-mediated endocytosis(GO:2001287)
1.2 10.7 GO:0001661 conditioned taste aversion(GO:0001661)
0.5 1.5 GO:0008057 eye pigment granule organization(GO:0008057)
0.4 2.1 GO:1900106 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.3 1.4 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.3 8.4 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.3 0.8 GO:0021577 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
0.2 0.9 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.2 2.0 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.2 1.5 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.1 0.9 GO:0046469 plasma lipoprotein particle oxidation(GO:0034441) platelet activating factor metabolic process(GO:0046469)
0.1 1.4 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.1 0.4 GO:0015881 creatine transport(GO:0015881) creatine transmembrane transport(GO:1902598)
0.1 2.1 GO:0035878 nail development(GO:0035878)
0.1 1.2 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.1 2.7 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.1 1.4 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.1 1.3 GO:0043248 proteasome assembly(GO:0043248)
0.1 0.4 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.1 0.9 GO:0099612 protein localization to axon(GO:0099612)
0.1 0.9 GO:0019896 axonal transport of mitochondrion(GO:0019896)
0.1 0.4 GO:0006543 glutamine catabolic process(GO:0006543)
0.0 0.6 GO:0034378 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) chylomicron assembly(GO:0034378) positive regulation of viral entry into host cell(GO:0046598)
0.0 0.6 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.0 0.3 GO:1904222 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.0 1.8 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.0 0.1 GO:0032223 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.0 0.8 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.3 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 1.2 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.0 0.7 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0 0.1 GO:0014735 regulation of muscle atrophy(GO:0014735) response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.0 0.1 GO:0099538 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551)
0.0 1.2 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.1 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.1 GO:0071400 cellular response to oleic acid(GO:0071400)
0.0 0.1 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.4 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 2.1 GO:0048477 oogenesis(GO:0048477)
0.0 0.4 GO:0001946 lymphangiogenesis(GO:0001946)
0.0 0.4 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.2 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 0.1 GO:0003322 pancreatic A cell development(GO:0003322)
0.0 0.0 GO:1901383 negative regulation of chorionic trophoblast cell proliferation(GO:1901383)
0.0 0.4 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 10.7 GO:0035976 AP1 complex(GO:0035976)
1.0 4.9 GO:0044393 microspike(GO:0044393)
0.7 2.1 GO:0036117 hyaluranon cable(GO:0036117)
0.2 0.6 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.1 0.9 GO:1990769 proximal neuron projection(GO:1990769)
0.1 1.3 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 1.9 GO:0030056 hemidesmosome(GO:0030056)
0.0 2.0 GO:0030057 desmosome(GO:0030057)
0.0 0.8 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 1.4 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.1 GO:0033011 perinuclear theca(GO:0033011)
0.0 0.9 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.8 GO:0042599 lamellar body(GO:0042599)
0.0 1.4 GO:0032590 dendrite membrane(GO:0032590)
0.0 0.5 GO:0005614 interstitial matrix(GO:0005614)
0.0 1.2 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.8 GO:1904115 axon cytoplasm(GO:1904115)
0.0 1.6 GO:0030864 cortical actin cytoskeleton(GO:0030864)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 7.7 GO:0042015 interleukin-20 binding(GO:0042015)
0.4 2.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.4 1.2 GO:0052857 NADHX epimerase activity(GO:0052856) NADPHX epimerase activity(GO:0052857)
0.3 0.9 GO:0004019 adenylosuccinate synthase activity(GO:0004019)
0.2 1.2 GO:0016936 galactoside binding(GO:0016936)
0.2 1.2 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.2 2.0 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.2 1.4 GO:0042610 CD8 receptor binding(GO:0042610)
0.1 2.1 GO:0038132 neuregulin binding(GO:0038132)
0.1 10.8 GO:0070412 R-SMAD binding(GO:0070412)
0.1 0.4 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.1 0.4 GO:0005308 creatine transmembrane transporter activity(GO:0005308)
0.1 0.9 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.1 1.5 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.1 1.4 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.1 1.5 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 1.4 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 0.6 GO:0019798 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.1 0.6 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.1 4.9 GO:0015485 cholesterol binding(GO:0015485)
0.1 8.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 2.2 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.4 GO:0004359 glutaminase activity(GO:0004359)
0.0 2.5 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 2.7 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.9 GO:0050811 GABA receptor binding(GO:0050811)
0.0 1.5 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.1 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.0 0.8 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.1 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 0.8 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.1 GO:0060175 brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.0 2.1 GO:0005496 steroid binding(GO:0005496)
0.0 0.1 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.0 0.3 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 1.8 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.3 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.5 GO:0005112 Notch binding(GO:0005112)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 10.7 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 2.1 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 1.4 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 2.9 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.9 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 4.1 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.4 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 10.0 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 2.1 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 1.4 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.1 1.2 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 0.8 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 1.9 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 1.0 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.9 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.6 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 1.6 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.5 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 1.3 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 1.2 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.8 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 1.9 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 0.4 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)