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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for VDR

Z-value: 1.46

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Transcription factors associated with VDR

Gene Symbol Gene ID Gene Info
VDR
ENSG00000111424.6 vitamin D receptor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
VDRhg19_v2_chr12_-_48276710_48276725-0.233.2e-01Click!

Activity profile of VDR motif

Sorted Z-values of VDR motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_31916733 4.22 ENST00000483004.1
CFB
complement factor B
chr16_-_2770216 3.05 ENST00000302641.3
PRSS27
protease, serine 27
chr7_-_45960850 2.94 ENST00000381083.4
ENST00000381086.5
ENST00000275521.6
IGFBP3
insulin-like growth factor binding protein 3
chr11_+_65266507 2.41 ENST00000544868.1
MALAT1
metastasis associated lung adenocarcinoma transcript 1 (non-protein coding)
chr16_-_30107491 2.07 ENST00000566134.1
ENST00000565110.1
ENST00000398841.1
ENST00000398838.4
YPEL3
yippee-like 3 (Drosophila)
chr20_+_36974759 2.03 ENST00000217407.2
LBP
lipopolysaccharide binding protein
chr19_+_13261216 2.01 ENST00000587885.1
ENST00000292433.3
IER2
immediate early response 2
chr17_+_27895609 1.93 ENST00000581411.2
ENST00000301057.7
TP53I13
tumor protein p53 inducible protein 13
chr2_+_108905095 1.88 ENST00000251481.6
ENST00000326853.5
SULT1C2
sulfotransferase family, cytosolic, 1C, member 2
chr17_-_34808047 1.77 ENST00000592614.1
ENST00000591542.1
ENST00000330458.7
ENST00000341264.6
ENST00000592987.1
ENST00000400684.4
TBC1D3G
TBC1D3H
TBC1 domain family, member 3G
TBC1 domain family, member 3H
chr7_-_95025661 1.71 ENST00000542556.1
ENST00000265627.5
ENST00000427422.1
ENST00000451904.1
PON1
PON3
paraoxonase 1
paraoxonase 3
chr1_+_200993071 1.70 ENST00000446333.1
ENST00000458003.1
RP11-168O16.1
RP11-168O16.1
chr17_-_36348610 1.69 ENST00000339023.4
ENST00000354664.4
TBC1D3
TBC1 domain family, member 3
chr17_-_7082861 1.68 ENST00000269299.3
ASGR1
asialoglycoprotein receptor 1
chr2_+_108905325 1.67 ENST00000438339.1
ENST00000409880.1
ENST00000437390.2
SULT1C2
sulfotransferase family, cytosolic, 1C, member 2
chr9_+_139839711 1.67 ENST00000224181.3
C8G
complement component 8, gamma polypeptide
chr19_+_589893 1.60 ENST00000251287.2
HCN2
hyperpolarization activated cyclic nucleotide-gated potassium channel 2
chr17_-_79212825 1.57 ENST00000374769.2
ENTHD2
ENTH domain containing 2
chr17_-_64225508 1.54 ENST00000205948.6
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr11_-_73882029 1.52 ENST00000539061.1
C2CD3
C2 calcium-dependent domain containing 3
chr22_-_29663954 1.50 ENST00000216085.7
RHBDD3
rhomboid domain containing 3
chr16_-_30023615 1.48 ENST00000564979.1
ENST00000563378.1
DOC2A
double C2-like domains, alpha
chr17_-_36347835 1.47 ENST00000519532.1
TBC1D3
TBC1 domain family, member 3
chr17_-_34807272 1.47 ENST00000535592.1
ENST00000394453.1
TBC1D3G
TBC1 domain family, member 3G
chr16_+_2076869 1.43 ENST00000424542.2
ENST00000432365.2
SLC9A3R2
solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
chr17_-_34756219 1.39 ENST00000451448.2
ENST00000394359.3
TBC1D3C
TBC1D3H
TBC1 domain family, member 3C
TBC1 domain family, member 3H
chr8_+_9183618 1.39 ENST00000518619.1
RP11-115J16.1
RP11-115J16.1
chr14_-_35873856 1.39 ENST00000553342.1
ENST00000216797.5
ENST00000557140.1
NFKBIA
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
chr17_-_79791118 1.38 ENST00000576431.1
ENST00000575061.1
ENST00000455127.2
ENST00000572645.1
ENST00000538396.1
ENST00000573478.1
FAM195B
family with sequence similarity 195, member B
chr19_+_38826415 1.33 ENST00000410018.1
ENST00000409235.3
CATSPERG
catsper channel auxiliary subunit gamma
chr17_+_36284791 1.32 ENST00000505415.1
TBC1D3F
TBC1 domain family, member 3F
chr16_-_2260834 1.27 ENST00000562360.1
ENST00000566018.1
BRICD5
BRICHOS domain containing 5
chr6_+_31802685 1.27 ENST00000375639.2
ENST00000375638.3
ENST00000375635.2
ENST00000375642.2
ENST00000395789.1
C6orf48
chromosome 6 open reading frame 48
chr12_-_53575120 1.25 ENST00000542115.1
CSAD
cysteine sulfinic acid decarboxylase
chr11_+_63998198 1.24 ENST00000321460.5
DNAJC4
DnaJ (Hsp40) homolog, subfamily C, member 4
chr16_+_1128781 1.22 ENST00000293897.4
ENST00000562758.1
SSTR5
somatostatin receptor 5
chr20_+_3801162 1.22 ENST00000379573.2
ENST00000379567.2
ENST00000455742.1
ENST00000246041.2
AP5S1
adaptor-related protein complex 5, sigma 1 subunit
chr19_+_18530146 1.20 ENST00000348495.6
ENST00000270061.7
SSBP4
single stranded DNA binding protein 4
chr8_+_17434689 1.16 ENST00000398074.3
PDGFRL
platelet-derived growth factor receptor-like
chr16_-_67217844 1.15 ENST00000563902.1
ENST00000561621.1
ENST00000290881.7
KIAA0895L
KIAA0895-like
chr7_-_16844611 1.10 ENST00000401412.1
ENST00000419304.2
AGR2
anterior gradient 2
chr17_-_79212884 1.09 ENST00000300714.3
ENTHD2
ENTH domain containing 2
chr15_-_75230478 1.08 ENST00000322347.6
COX5A
cytochrome c oxidase subunit Va
chrX_+_70435044 1.08 ENST00000374029.1
ENST00000374022.3
ENST00000447581.1
GJB1
gap junction protein, beta 1, 32kDa
chr19_-_49122384 1.07 ENST00000550973.1
ENST00000550645.1
ENST00000549273.1
ENST00000552588.1
RPL18
ribosomal protein L18
chr9_+_139839686 1.06 ENST00000371634.2
C8G
complement component 8, gamma polypeptide
chr16_+_14802801 1.04 ENST00000526520.1
ENST00000531598.2
NPIPA3
nuclear pore complex interacting protein family, member A3
chr14_-_62217779 1.02 ENST00000554254.1
HIF1A-AS2
HIF1A antisense RNA 2
chr7_-_22539771 1.02 ENST00000406890.2
ENST00000424363.1
STEAP1B
STEAP family member 1B
chr4_-_23735183 1.01 ENST00000507666.1
RP11-380P13.2
RP11-380P13.2
chr19_+_56652686 0.99 ENST00000592949.1
ZNF444
zinc finger protein 444
chr6_-_25874440 0.99 ENST00000361703.6
ENST00000397060.4
SLC17A3
solute carrier family 17 (organic anion transporter), member 3
chr19_-_47987419 0.98 ENST00000536339.1
ENST00000595554.1
ENST00000600271.1
ENST00000338134.3
KPTN
kaptin (actin binding protein)
chr10_-_76995769 0.97 ENST00000372538.3
COMTD1
catechol-O-methyltransferase domain containing 1
chr8_+_119294456 0.96 ENST00000366457.2
AC023590.1
Uncharacterized protein
chr10_+_54074033 0.95 ENST00000373970.3
DKK1
dickkopf WNT signaling pathway inhibitor 1
chr3_+_48264816 0.93 ENST00000296435.2
ENST00000576243.1
CAMP
cathelicidin antimicrobial peptide
chr1_+_198608146 0.89 ENST00000367376.2
ENST00000352140.3
ENST00000594404.1
ENST00000598951.1
ENST00000530727.1
ENST00000442510.2
ENST00000367367.4
ENST00000348564.6
ENST00000367364.1
ENST00000413409.2
PTPRC
protein tyrosine phosphatase, receptor type, C
chr6_+_46661575 0.88 ENST00000450697.1
TDRD6
tudor domain containing 6
chr17_-_79805146 0.88 ENST00000415593.1
P4HB
prolyl 4-hydroxylase, beta polypeptide
chr5_-_147211226 0.88 ENST00000296695.5
SPINK1
serine peptidase inhibitor, Kazal type 1
chr19_+_50031547 0.88 ENST00000597801.1
RCN3
reticulocalbin 3, EF-hand calcium binding domain
chr20_-_62129163 0.87 ENST00000298049.7
EEF1A2
eukaryotic translation elongation factor 1 alpha 2
chr12_-_58135903 0.87 ENST00000257897.3
AGAP2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr12_-_6579808 0.86 ENST00000535180.1
ENST00000400911.3
VAMP1
vesicle-associated membrane protein 1 (synaptobrevin 1)
chr9_-_138391692 0.85 ENST00000429260.2
C9orf116
chromosome 9 open reading frame 116
chr7_+_29234101 0.84 ENST00000435288.2
CHN2
chimerin 2
chr16_+_67207872 0.84 ENST00000563258.1
ENST00000568146.1
NOL3
nucleolar protein 3 (apoptosis repressor with CARD domain)
chr8_-_93115445 0.83 ENST00000523629.1
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr16_+_67207838 0.82 ENST00000566871.1
ENST00000268605.7
NOL3
nucleolar protein 3 (apoptosis repressor with CARD domain)
chr1_+_44457261 0.81 ENST00000372318.3
CCDC24
coiled-coil domain containing 24
chr2_-_203736334 0.77 ENST00000392237.2
ENST00000416760.1
ENST00000412210.1
ICA1L
islet cell autoantigen 1,69kDa-like
chr10_+_104154229 0.76 ENST00000428099.1
ENST00000369966.3
NFKB2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr15_-_75230368 0.76 ENST00000564811.1
ENST00000562233.1
ENST00000567270.1
ENST00000568783.1
COX5A
cytochrome c oxidase subunit Va
chr11_+_65154070 0.75 ENST00000317568.5
ENST00000531296.1
ENST00000533782.1
ENST00000355991.5
ENST00000416776.2
ENST00000526201.1
FRMD8
FERM domain containing 8
chr19_+_18530184 0.74 ENST00000601357.2
SSBP4
single stranded DNA binding protein 4
chr17_+_28884130 0.74 ENST00000580161.1
TBC1D29
TBC1 domain family, member 29
chr16_-_31106211 0.74 ENST00000532364.1
ENST00000529564.1
ENST00000319788.7
ENST00000354895.4
ENST00000394975.2
RP11-196G11.1
VKORC1
Uncharacterized protein
vitamin K epoxide reductase complex, subunit 1
chr19_+_44037334 0.73 ENST00000314228.5
ZNF575
zinc finger protein 575
chr19_+_56653064 0.72 ENST00000593100.1
ZNF444
zinc finger protein 444
chr16_-_87799505 0.72 ENST00000353170.5
ENST00000561825.1
ENST00000270583.5
ENST00000562261.1
ENST00000347925.5
KLHDC4
kelch domain containing 4
chr17_-_34591208 0.72 ENST00000336331.5
TBC1D3C
TBC1 domain family, member 3C
chr17_+_68100989 0.72 ENST00000585558.1
ENST00000392670.1
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chr19_-_11494975 0.72 ENST00000222139.6
ENST00000592375.2
EPOR
erythropoietin receptor
chr11_-_60719213 0.71 ENST00000227880.3
SLC15A3
solute carrier family 15 (oligopeptide transporter), member 3
chr8_+_9046503 0.71 ENST00000512942.2
RP11-10A14.5
RP11-10A14.5
chr15_-_72563585 0.70 ENST00000287196.9
ENST00000260376.7
PARP6
poly (ADP-ribose) polymerase family, member 6
chr2_+_113342163 0.70 ENST00000409719.1
CHCHD5
coiled-coil-helix-coiled-coil-helix domain containing 5
chr19_+_56652643 0.70 ENST00000586123.1
ZNF444
zinc finger protein 444
chr5_-_179227540 0.69 ENST00000520875.1
MGAT4B
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B
chr19_-_8386238 0.69 ENST00000301457.2
NDUFA7
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa
chr16_-_67260691 0.69 ENST00000447579.1
ENST00000393992.1
ENST00000424285.1
LRRC29
leucine rich repeat containing 29
chr16_-_31106048 0.68 ENST00000300851.6
VKORC1
vitamin K epoxide reductase complex, subunit 1
chr3_-_178969403 0.68 ENST00000314235.5
ENST00000392685.2
KCNMB3
potassium large conductance calcium-activated channel, subfamily M beta member 3
chr7_+_29234028 0.67 ENST00000222792.6
CHN2
chimerin 2
chr19_-_54693401 0.67 ENST00000338624.6
MBOAT7
membrane bound O-acyltransferase domain containing 7
chr2_+_169926047 0.65 ENST00000428522.1
ENST00000450153.1
ENST00000421653.1
DHRS9
dehydrogenase/reductase (SDR family) member 9
chr22_+_18593507 0.65 ENST00000330423.3
TUBA8
tubulin, alpha 8
chr16_+_31044812 0.64 ENST00000313843.3
STX4
syntaxin 4
chr11_-_104817919 0.64 ENST00000533252.1
CASP4
caspase 4, apoptosis-related cysteine peptidase
chr10_-_22292613 0.63 ENST00000376980.3
DNAJC1
DnaJ (Hsp40) homolog, subfamily C, member 1
chr7_+_99699280 0.63 ENST00000421755.1
AP4M1
adaptor-related protein complex 4, mu 1 subunit
chr16_-_28936493 0.62 ENST00000544477.1
ENST00000357573.6
RABEP2
rabaptin, RAB GTPase binding effector protein 2
chr14_-_20801427 0.62 ENST00000557665.1
ENST00000358932.4
ENST00000353689.4
CCNB1IP1
cyclin B1 interacting protein 1, E3 ubiquitin protein ligase
chr17_-_46716647 0.62 ENST00000608940.1
RP11-357H14.17
RP11-357H14.17
chrX_+_122993827 0.61 ENST00000371199.3
XIAP
X-linked inhibitor of apoptosis
chr4_+_39640754 0.61 ENST00000529094.1
ENST00000533736.1
RP11-539G18.2
RP11-539G18.2
chr17_+_43224684 0.59 ENST00000332499.2
HEXIM1
hexamethylene bis-acetamide inducible 1
chr16_+_28834303 0.58 ENST00000340394.8
ENST00000325215.6
ENST00000395547.2
ENST00000336783.4
ENST00000382686.4
ENST00000564304.1
ATXN2L
ataxin 2-like
chr5_+_175487692 0.57 ENST00000510151.1
FAM153B
family with sequence similarity 153, member B
chr11_+_82783097 0.57 ENST00000501011.2
ENST00000527627.1
ENST00000526795.1
ENST00000533528.1
ENST00000533708.1
ENST00000534499.1
RAB30-AS1
RAB30 antisense RNA 1 (head to head)
chr19_+_36142147 0.56 ENST00000590618.1
COX6B1
cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous)
chr18_+_9102669 0.55 ENST00000497577.2
NDUFV2
NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa
chr19_-_5903714 0.55 ENST00000586349.1
ENST00000585661.1
ENST00000308961.4
ENST00000592634.1
ENST00000418389.2
ENST00000252675.5
AC024592.12
NDUFA11
FUT5
Uncharacterized protein
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa
fucosyltransferase 5 (alpha (1,3) fucosyltransferase)
chr3_-_122283100 0.54 ENST00000492382.1
ENST00000462315.1
PARP9
poly (ADP-ribose) polymerase family, member 9
chr7_+_1272522 0.54 ENST00000316333.8
UNCX
UNC homeobox
chr5_-_177209832 0.54 ENST00000393518.3
ENST00000505531.1
ENST00000503567.1
FAM153A
family with sequence similarity 153, member A
chr12_+_57857475 0.54 ENST00000528467.1
GLI1
GLI family zinc finger 1
chr15_-_59949667 0.53 ENST00000396061.1
GTF2A2
general transcription factor IIA, 2, 12kDa
chr2_+_210518057 0.53 ENST00000452717.1
MAP2
microtubule-associated protein 2
chr11_-_104840093 0.53 ENST00000417440.2
ENST00000444739.2
CASP4
caspase 4, apoptosis-related cysteine peptidase
chr11_-_6624801 0.53 ENST00000534343.1
ENST00000254605.6
RRP8
ribosomal RNA processing 8, methyltransferase, homolog (yeast)
chr16_-_28937027 0.53 ENST00000358201.4
RABEP2
rabaptin, RAB GTPase binding effector protein 2
chr6_+_13272904 0.52 ENST00000379335.3
ENST00000379329.1
PHACTR1
phosphatase and actin regulator 1
chrX_-_47518527 0.52 ENST00000333119.3
UXT
ubiquitously-expressed, prefoldin-like chaperone
chr12_-_6579833 0.52 ENST00000396308.3
VAMP1
vesicle-associated membrane protein 1 (synaptobrevin 1)
chr22_-_29663690 0.52 ENST00000406335.1
RHBDD3
rhomboid domain containing 3
chr2_+_220363579 0.52 ENST00000313597.5
ENST00000373917.3
ENST00000358215.3
ENST00000373908.1
ENST00000455657.1
ENST00000435316.1
ENST00000341142.3
GMPPA
GDP-mannose pyrophosphorylase A
chr7_-_92777606 0.52 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
SAMD9L
sterile alpha motif domain containing 9-like
chrX_+_100646190 0.51 ENST00000471855.1
RPL36A
ribosomal protein L36a
chr8_+_12809093 0.50 ENST00000528753.2
KIAA1456
KIAA1456
chr12_-_133050726 0.50 ENST00000595994.1
MUC8
mucin 8
chr19_+_1407517 0.50 ENST00000336761.6
ENST00000233078.4
DAZAP1
DAZ associated protein 1
chr12_+_48178706 0.50 ENST00000599515.1
AC004466.1
Uncharacterized protein
chr12_-_25348007 0.50 ENST00000354189.5
ENST00000545133.1
ENST00000554347.1
ENST00000395987.3
ENST00000320267.9
ENST00000395990.2
ENST00000537577.1
CASC1
cancer susceptibility candidate 1
chr16_-_68404908 0.50 ENST00000574662.1
SMPD3
sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)
chr16_+_57392684 0.49 ENST00000219235.4
CCL22
chemokine (C-C motif) ligand 22
chr6_-_30524951 0.49 ENST00000376621.3
GNL1
guanine nucleotide binding protein-like 1
chr10_-_18940501 0.49 ENST00000377304.4
NSUN6
NOP2/Sun domain family, member 6
chr19_+_18077881 0.49 ENST00000609922.1
KCNN1
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1
chr1_+_92414952 0.48 ENST00000449584.1
ENST00000427104.1
ENST00000355011.3
ENST00000448194.1
ENST00000426141.1
ENST00000450792.1
ENST00000548992.1
ENST00000552654.1
ENST00000457265.1
BRDT
bromodomain, testis-specific
chr19_+_49122785 0.48 ENST00000598088.1
SPHK2
sphingosine kinase 2
chr2_-_32489922 0.48 ENST00000402280.1
NLRC4
NLR family, CARD domain containing 4
chr3_-_54962100 0.47 ENST00000273286.5
LRTM1
leucine-rich repeats and transmembrane domains 1
chr15_+_68115895 0.47 ENST00000554240.1
SKOR1
SKI family transcriptional corepressor 1
chrX_+_100645812 0.47 ENST00000427805.2
ENST00000553110.3
ENST00000392994.3
ENST00000409338.1
ENST00000409170.3
RPL36A
RPL36A-HNRNPH2
ribosomal protein L36a
RPL36A-HNRNPH2 readthrough
chr10_+_119301928 0.46 ENST00000553456.3
EMX2
empty spiracles homeobox 2
chr11_-_65667884 0.46 ENST00000448083.2
ENST00000531493.1
ENST00000532401.1
FOSL1
FOS-like antigen 1
chr9_-_130617029 0.45 ENST00000373203.4
ENG
endoglin
chr2_-_203736150 0.45 ENST00000457524.1
ENST00000421334.1
ICA1L
islet cell autoantigen 1,69kDa-like
chr16_-_67281413 0.45 ENST00000258201.4
FHOD1
formin homology 2 domain containing 1
chr2_+_54342574 0.45 ENST00000303536.4
ENST00000394666.3
ACYP2
acylphosphatase 2, muscle type
chr16_+_16043406 0.45 ENST00000399410.3
ENST00000399408.2
ENST00000346370.5
ENST00000351154.5
ENST00000345148.5
ENST00000349029.5
ABCC1
ATP-binding cassette, sub-family C (CFTR/MRP), member 1
chr1_+_54703710 0.45 ENST00000361350.4
SSBP3-AS1
SSBP3 antisense RNA 1
chr9_+_12685439 0.44 ENST00000473763.1
TYRP1
tyrosinase-related protein 1
chr4_-_39640700 0.44 ENST00000295958.5
SMIM14
small integral membrane protein 14
chr16_-_31105870 0.44 ENST00000394971.3
VKORC1
vitamin K epoxide reductase complex, subunit 1
chr19_+_50270219 0.43 ENST00000354293.5
ENST00000359032.5
AP2A1
adaptor-related protein complex 2, alpha 1 subunit
chr19_+_41281282 0.43 ENST00000263369.3
MIA
melanoma inhibitory activity
chr3_+_54157480 0.43 ENST00000490478.1
CACNA2D3
calcium channel, voltage-dependent, alpha 2/delta subunit 3
chr16_+_19078911 0.43 ENST00000321998.5
COQ7
coenzyme Q7 homolog, ubiquinone (yeast)
chr22_+_18593446 0.42 ENST00000316027.6
TUBA8
tubulin, alpha 8
chr9_-_130616915 0.42 ENST00000344849.3
ENG
endoglin
chr2_+_87769459 0.42 ENST00000414030.1
ENST00000437561.1
LINC00152
long intergenic non-protein coding RNA 152
chr22_+_50624323 0.42 ENST00000380909.4
ENST00000303434.4
TRABD
TraB domain containing
chr1_-_110613276 0.42 ENST00000369792.4
ALX3
ALX homeobox 3
chr13_+_113656022 0.41 ENST00000423482.2
MCF2L
MCF.2 cell line derived transforming sequence-like
chr19_-_13261160 0.41 ENST00000343587.5
ENST00000591197.1
STX10
syntaxin 10
chr15_+_76030311 0.41 ENST00000543887.1
AC019294.1
AC019294.1
chr21_+_25801041 0.41 ENST00000453784.2
ENST00000423581.1
AP000476.1
AP000476.1
chrX_-_47518498 0.40 ENST00000335890.2
UXT
ubiquitously-expressed, prefoldin-like chaperone
chr6_-_32145101 0.40 ENST00000375104.2
AGPAT1
1-acylglycerol-3-phosphate O-acyltransferase 1
chr17_-_43487780 0.39 ENST00000532038.1
ENST00000528677.1
ARHGAP27
Rho GTPase activating protein 27
chr1_+_44457441 0.39 ENST00000466180.1
CCDC24
coiled-coil domain containing 24
chr6_+_30525051 0.39 ENST00000376557.3
PRR3
proline rich 3
chr12_+_53895364 0.39 ENST00000552817.1
ENST00000394357.2
TARBP2
TAR (HIV-1) RNA binding protein 2
chr8_-_135522425 0.39 ENST00000521673.1
ZFAT
zinc finger and AT hook domain containing
chr6_+_35227449 0.38 ENST00000373953.3
ENST00000440666.2
ENST00000339411.5
ZNF76
zinc finger protein 76
chr1_+_153750622 0.38 ENST00000532853.1
SLC27A3
solute carrier family 27 (fatty acid transporter), member 3
chr12_+_57610562 0.38 ENST00000349394.5
NXPH4
neurexophilin 4
chr6_-_42016385 0.38 ENST00000502771.1
ENST00000508143.1
ENST00000514588.1
ENST00000510503.1
ENST00000415497.2
ENST00000372988.4
CCND3
cyclin D3
chr7_-_36764004 0.38 ENST00000431169.1
AOAH
acyloxyacyl hydrolase (neutrophil)
chr8_+_12809531 0.37 ENST00000532376.2
KIAA1456
KIAA1456
chr9_-_34376851 0.37 ENST00000297625.7
KIAA1161
KIAA1161
chr11_+_57365150 0.37 ENST00000457869.1
ENST00000340687.6
ENST00000378323.4
ENST00000378324.2
ENST00000403558.1
SERPING1
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
chr1_-_200992827 0.37 ENST00000332129.2
ENST00000422435.2
KIF21B
kinesin family member 21B
chr5_+_177433973 0.37 ENST00000507848.1
FAM153C
family with sequence similarity 153, member C
chr6_+_30524663 0.36 ENST00000376560.3
PRR3
proline rich 3
chr19_-_12595586 0.36 ENST00000397732.3
ZNF709
zinc finger protein 709
chr2_+_177134134 0.36 ENST00000249442.6
ENST00000392529.2
ENST00000443241.1
MTX2
metaxin 2
chr16_+_23765948 0.35 ENST00000300113.2
CHP2
calcineurin-like EF-hand protein 2
chr8_-_22926623 0.35 ENST00000276431.4
TNFRSF10B
tumor necrosis factor receptor superfamily, member 10b
chr2_+_233527443 0.35 ENST00000410095.1
EFHD1
EF-hand domain family, member D1
chr1_-_19426149 0.35 ENST00000429347.2
UBR4
ubiquitin protein ligase E3 component n-recognin 4
chr7_-_72722783 0.34 ENST00000428206.1
ENST00000252594.6
ENST00000310326.8
ENST00000438747.2
NSUN5
NOP2/Sun domain family, member 5
chr9_-_139839064 0.34 ENST00000325285.3
ENST00000428398.1
FBXW5
F-box and WD repeat domain containing 5
chr1_-_221915418 0.34 ENST00000323825.3
ENST00000366899.3
DUSP10
dual specificity phosphatase 10
chr2_+_231280954 0.34 ENST00000409824.1
ENST00000409341.1
ENST00000409112.1
ENST00000340126.4
ENST00000341950.4
SP100
SP100 nuclear antigen
chr12_+_56552128 0.34 ENST00000548580.1
ENST00000293422.5
ENST00000348108.4
ENST00000549017.1
ENST00000549566.1
ENST00000536128.1
ENST00000547649.1
ENST00000547408.1
ENST00000551589.1
ENST00000549392.1
ENST00000548400.1
ENST00000548293.1
MYL6
myosin, light chain 6, alkali, smooth muscle and non-muscle
chr19_+_41281060 0.33 ENST00000594436.1
ENST00000597784.1
MIA
melanoma inhibitory activity

Network of associatons between targets according to the STRING database.

First level regulatory network of VDR

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0015920 leukocyte chemotaxis involved in inflammatory response(GO:0002232) lipopolysaccharide transport(GO:0015920)
0.6 1.7 GO:0014876 response to injury involved in regulation of muscle adaptation(GO:0014876)
0.4 1.7 GO:0034445 regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445) phenylpropanoid catabolic process(GO:0046271)
0.3 1.0 GO:0038162 erythropoietin-mediated signaling pathway(GO:0038162)
0.3 1.0 GO:0090381 regulation of heart induction(GO:0090381) regulation of heart induction by canonical Wnt signaling pathway(GO:0100012) regulation of midbrain dopaminergic neuron differentiation(GO:1904956)
0.3 6.9 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.3 0.9 GO:0001300 chronological cell aging(GO:0001300)
0.3 0.8 GO:0051037 regulation of transcription involved in meiotic cell cycle(GO:0051037)
0.2 1.2 GO:0042412 taurine biosynthetic process(GO:0042412)
0.2 1.2 GO:0038169 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.2 2.0 GO:0032815 negative regulation of natural killer cell activation(GO:0032815)
0.2 0.6 GO:0043311 regulation of eosinophil degranulation(GO:0043309) positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.2 0.8 GO:1902530 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
0.2 1.2 GO:0010751 negative regulation of nitric oxide mediated signal transduction(GO:0010751)
0.2 1.5 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.2 0.8 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
0.2 0.7 GO:0006669 sphinganine-1-phosphate biosynthetic process(GO:0006669)
0.2 0.9 GO:0035701 hematopoietic stem cell migration(GO:0035701)
0.2 1.4 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.2 1.1 GO:1903899 lung goblet cell differentiation(GO:0060480) positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.1 0.4 GO:0043438 acetoacetic acid metabolic process(GO:0043438)
0.1 3.3 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.1 0.5 GO:0060032 notochord regression(GO:0060032)
0.1 1.6 GO:0071321 cellular response to cGMP(GO:0071321)
0.1 1.0 GO:0097461 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.1 0.4 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.1 0.3 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.1 1.2 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.1 0.3 GO:0034963 box C/D snoRNA 3'-end processing(GO:0000494) box C/D snoRNA metabolic process(GO:0033967) box C/D snoRNA processing(GO:0034963) histone glutamine methylation(GO:1990258)
0.1 1.3 GO:0042373 vitamin K metabolic process(GO:0042373)
0.1 3.5 GO:0051923 sulfation(GO:0051923)
0.1 2.1 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.1 0.8 GO:0007296 vitellogenesis(GO:0007296)
0.1 0.9 GO:0051852 disruption by host of symbiont cells(GO:0051852) killing by host of symbiont cells(GO:0051873)
0.1 2.4 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 0.5 GO:0051610 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.1 0.3 GO:0006788 heme oxidation(GO:0006788) negative regulation of mast cell cytokine production(GO:0032764)
0.1 0.5 GO:0043606 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.1 0.3 GO:0060168 positive regulation of adenosine receptor signaling pathway(GO:0060168)
0.1 0.3 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.1 0.9 GO:0034378 chylomicron assembly(GO:0034378) positive regulation of viral entry into host cell(GO:0046598)
0.1 0.2 GO:0070407 oxidation-dependent protein catabolic process(GO:0070407)
0.1 0.4 GO:0030423 targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.1 0.8 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.1 0.9 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.1 0.2 GO:1904815 negative regulation of protein localization to chromosome, telomeric region(GO:1904815)
0.1 0.4 GO:0061107 seminal vesicle development(GO:0061107)
0.1 0.5 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.1 0.5 GO:1902044 regulation of Fas signaling pathway(GO:1902044)
0.1 0.6 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.1 1.0 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.1 0.6 GO:0051026 chiasma assembly(GO:0051026)
0.1 0.4 GO:0035672 oligopeptide transmembrane transport(GO:0035672)
0.1 1.4 GO:0035493 SNARE complex assembly(GO:0035493)
0.1 9.5 GO:0090630 activation of GTPase activity(GO:0090630)
0.1 0.5 GO:0070269 pyroptosis(GO:0070269)
0.1 1.1 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.1 0.2 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.0 1.1 GO:0015868 purine ribonucleotide transport(GO:0015868)
0.0 0.2 GO:0002399 MHC class II protein complex assembly(GO:0002399)
0.0 0.5 GO:0046015 regulation of transcription by glucose(GO:0046015)
0.0 0.3 GO:0042427 serotonin biosynthetic process(GO:0042427)
0.0 0.5 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.3 GO:1903575 cornified envelope assembly(GO:1903575)
0.0 0.2 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.0 0.2 GO:0002625 regulation of T cell antigen processing and presentation(GO:0002625)
0.0 1.2 GO:0035791 platelet-derived growth factor receptor-beta signaling pathway(GO:0035791)
0.0 0.3 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.0 0.2 GO:0042369 vitamin D catabolic process(GO:0042369)
0.0 0.3 GO:0045229 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.0 0.4 GO:0051660 establishment of centrosome localization(GO:0051660)
0.0 0.5 GO:0019317 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 0.3 GO:0055011 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.0 0.5 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.1 GO:0030185 nitric oxide transport(GO:0030185) carbon dioxide transmembrane transport(GO:0035378)
0.0 0.4 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.6 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.7 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.4 GO:0015824 proline transport(GO:0015824)
0.0 0.7 GO:0021819 layer formation in cerebral cortex(GO:0021819)
0.0 1.0 GO:0006855 drug transmembrane transport(GO:0006855)
0.0 0.6 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.0 0.1 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0 0.2 GO:0021997 neural plate axis specification(GO:0021997)
0.0 0.6 GO:0039692 single stranded viral RNA replication via double stranded DNA intermediate(GO:0039692)
0.0 0.2 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.0 0.9 GO:0034643 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.0 0.2 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 0.1 GO:0046603 negative regulation of mitotic centrosome separation(GO:0046603)
0.0 0.1 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.0 0.6 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 1.3 GO:0035036 sperm-egg recognition(GO:0035036)
0.0 0.2 GO:0036089 cleavage furrow formation(GO:0036089)
0.0 0.5 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 1.4 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.7 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.6 GO:1901798 positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.0 0.1 GO:0090625 mRNA cleavage involved in gene silencing by siRNA(GO:0090625)
0.0 0.3 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.0 1.7 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.3 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 0.1 GO:0048619 embryonic hindgut morphogenesis(GO:0048619)
0.0 0.1 GO:0015692 lead ion transport(GO:0015692)
0.0 0.2 GO:0030497 fatty acid elongation(GO:0030497)
0.0 0.3 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.2 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.0 0.0 GO:0019516 lactate oxidation(GO:0019516)
0.0 0.4 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 0.0 GO:0045062 extrathymic T cell selection(GO:0045062)
0.0 0.0 GO:1901052 sarcosine metabolic process(GO:1901052) sarcosine catabolic process(GO:1901053)
0.0 0.3 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.4 GO:0060712 spongiotrophoblast layer development(GO:0060712)
0.0 0.5 GO:0021542 dentate gyrus development(GO:0021542)
0.0 0.4 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0 0.0 GO:0040019 positive regulation of embryonic development(GO:0040019)
0.0 0.7 GO:0010107 potassium ion import(GO:0010107)
0.0 2.1 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.3 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.5 GO:0001893 maternal placenta development(GO:0001893)
0.0 0.3 GO:0072189 ureter development(GO:0072189)
0.0 0.7 GO:0019228 neuronal action potential(GO:0019228)
0.0 0.0 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.0 0.4 GO:0035115 embryonic forelimb morphogenesis(GO:0035115)
0.0 0.2 GO:0071803 positive regulation of podosome assembly(GO:0071803)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0098855 HCN channel complex(GO:0098855)
0.3 2.7 GO:0005579 membrane attack complex(GO:0005579)
0.3 2.9 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.3 0.9 GO:0072563 endothelial microparticle(GO:0072563)
0.2 0.9 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.2 0.8 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.2 1.6 GO:0072557 IPAF inflammasome complex(GO:0072557)
0.1 1.4 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 1.3 GO:0036128 CatSper complex(GO:0036128)
0.1 0.4 GO:0036024 protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183)
0.1 1.8 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 0.9 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1 1.8 GO:0031089 platelet dense granule lumen(GO:0031089)
0.1 1.7 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.1 0.6 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.1 0.6 GO:0032044 DSIF complex(GO:0032044)
0.1 0.5 GO:0033553 rDNA heterochromatin(GO:0033553)
0.1 0.9 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1 0.3 GO:0001652 granular component(GO:0001652)
0.1 0.6 GO:0000138 Golgi trans cisterna(GO:0000138)
0.1 3.0 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 0.7 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.9 GO:0033391 chromatoid body(GO:0033391)
0.0 0.6 GO:0000322 storage vacuole(GO:0000322)
0.0 0.1 GO:0070703 inner mucus layer(GO:0070702) outer mucus layer(GO:0070703)
0.0 1.0 GO:0005922 connexon complex(GO:0005922)
0.0 0.5 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.5 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.2 GO:1903439 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.0 0.7 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.0 0.1 GO:0020003 symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005)
0.0 0.2 GO:0098843 postsynaptic endocytic zone(GO:0098843)
0.0 0.3 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.9 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.1 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.2 GO:0001740 Barr body(GO:0001740)
0.0 0.4 GO:0032059 bleb(GO:0032059)
0.0 0.8 GO:0042734 presynaptic membrane(GO:0042734)
0.0 4.4 GO:0072562 blood microparticle(GO:0072562)
0.0 1.4 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.4 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.1 GO:0070826 paraferritin complex(GO:0070826)
0.0 2.1 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.3 GO:0097512 cardiac myofibril(GO:0097512)
0.0 1.0 GO:0032420 stereocilium(GO:0032420)
0.0 0.3 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 3.4 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.2 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 1.2 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 1.7 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 1.7 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 2.2 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.5 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.2 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.6 GO:0000795 synaptonemal complex(GO:0000795)
0.0 1.7 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.2 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.0 0.2 GO:0042613 MHC class II protein complex(GO:0042613)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 2.9 GO:0008160 protein tyrosine phosphatase activator activity(GO:0008160)
0.6 1.7 GO:0102007 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.4 1.9 GO:0016900 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.3 1.6 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.3 1.2 GO:0005019 platelet-derived growth factor beta-receptor activity(GO:0005019)
0.3 1.3 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.2 1.2 GO:0004782 sulfinoalanine decarboxylase activity(GO:0004782)
0.2 1.2 GO:0004994 somatostatin receptor activity(GO:0004994)
0.2 2.0 GO:0071723 lipoteichoic acid binding(GO:0070891) lipopeptide binding(GO:0071723)
0.2 1.7 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.2 6.5 GO:0001848 complement binding(GO:0001848)
0.2 0.5 GO:0004397 histidine ammonia-lyase activity(GO:0004397)
0.2 0.5 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.2 0.6 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.2 1.7 GO:0035877 death effector domain binding(GO:0035877)
0.1 0.4 GO:0015235 cobalamin transporter activity(GO:0015235)
0.1 0.4 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.1 1.0 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.1 3.5 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.1 1.0 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.1 0.3 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.1 0.9 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.1 0.9 GO:0005534 galactose binding(GO:0005534)
0.1 0.3 GO:0036009 protein-glutamine N-methyltransferase activity(GO:0036009) histone-glutamine methyltransferase activity(GO:1990259)
0.1 0.7 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.1 0.5 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.1 0.7 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 0.5 GO:0015333 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.1 0.5 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 0.4 GO:0003998 acylphosphatase activity(GO:0003998)
0.1 0.3 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.1 2.4 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 0.2 GO:0004019 adenylosuccinate synthase activity(GO:0004019)
0.1 0.3 GO:0052642 lysophosphatidic acid phosphatase activity(GO:0052642)
0.1 0.3 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.1 0.2 GO:0070361 mitochondrial light strand promoter anti-sense binding(GO:0070361) mitochondrial heavy strand promoter anti-sense binding(GO:0070362) mitochondrial heavy strand promoter sense binding(GO:0070364)
0.1 0.3 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.1 0.6 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.1 1.0 GO:0048019 receptor antagonist activity(GO:0048019)
0.1 0.3 GO:0016402 pristanoyl-CoA oxidase activity(GO:0016402)
0.1 1.1 GO:0005243 gap junction channel activity(GO:0005243)
0.1 0.2 GO:0004948 calcitonin receptor activity(GO:0004948)
0.1 0.5 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.6 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 1.2 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.2 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.0 0.7 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.0 0.3 GO:0034711 inhibin binding(GO:0034711)
0.0 0.5 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 1.6 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.4 GO:0070883 pre-miRNA binding(GO:0070883)
0.0 0.1 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.0 0.3 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0 0.4 GO:0032190 acrosin binding(GO:0032190)
0.0 0.3 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.9 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.3 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.0 0.7 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.2 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.0 1.5 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 8.0 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.7 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 1.0 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.9 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 1.3 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.9 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 1.4 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.7 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.3 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.0 0.5 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.4 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.1 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.0 0.3 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.4 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.2 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.0 0.1 GO:0015639 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.0 5.1 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.8 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.8 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.4 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.9 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.1 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.2 GO:0010385 double-stranded methylated DNA binding(GO:0010385)
0.0 0.5 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.4 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.0 GO:0008480 sarcosine dehydrogenase activity(GO:0008480)
0.0 0.2 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0 0.3 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.2 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.0 0.2 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.2 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.9 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 1.7 GO:0019905 syntaxin binding(GO:0019905)
0.0 0.5 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 1.7 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 1.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.2 GO:0005212 structural constituent of eye lens(GO:0005212)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.2 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 1.2 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 3.1 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 2.9 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 1.0 PID EPO PATHWAY EPO signaling pathway
0.0 1.0 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.8 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.9 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.4 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 1.0 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 1.5 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 1.5 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.4 PID ARF 3PATHWAY Arf1 pathway
0.0 0.5 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 1.2 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.6 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.9 PID LKB1 PATHWAY LKB1 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.2 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.1 3.5 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 1.9 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 2.7 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.1 1.8 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 1.2 REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS Genes involved in Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
0.1 1.0 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 4.4 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 1.0 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 1.1 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.4 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 1.0 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.5 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.7 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.0 1.2 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 3.8 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.0 0.6 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.7 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.4 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 2.9 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.5 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.4 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.4 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.6 REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.0 0.8 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 0.7 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.4 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.1 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors