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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for VENTX

Z-value: 0.30

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Transcription factors associated with VENTX

Gene Symbol Gene ID Gene Info
ENSG00000151650.7 VENT homeobox

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
VENTXhg19_v2_chr10_+_135050908_135050908-0.077.7e-01Click!

Activity profile of VENTX motif

Sorted Z-values of VENTX motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_155511887 0.74 ENST00000302053.3
ENST00000403106.3
fibrinogen alpha chain
chr11_+_123430948 0.69 ENST00000529432.1
ENST00000534764.1
GRAM domain containing 1B
chrX_+_106163626 0.65 ENST00000336803.1
claudin 2
chr5_-_156486120 0.53 ENST00000522693.1
hepatitis A virus cellular receptor 1
chr17_-_47045949 0.50 ENST00000357424.2
gastric inhibitory polypeptide
chr4_+_129732419 0.45 ENST00000510308.1
jade family PHD finger 1
chr6_+_12290586 0.39 ENST00000379375.5
endothelin 1
chr12_+_52695617 0.38 ENST00000293525.5
keratin 86
chr13_-_67802549 0.38 ENST00000328454.5
ENST00000377865.2
protocadherin 9
chr13_+_110958124 0.38 ENST00000400163.2
collagen, type IV, alpha 2
chr17_+_43239231 0.32 ENST00000591576.1
ENST00000591070.1
ENST00000592695.1
hexamethylene bis-acetamide inducible 2
chr18_+_20714525 0.31 ENST00000400473.2
Cdk5 and Abl enzyme substrate 1
chr20_-_25371412 0.30 ENST00000339157.5
ENST00000376542.3
abhydrolase domain containing 12
chr9_+_67968793 0.29 ENST00000417488.1
Protein LOC644249
chr14_-_27066636 0.29 ENST00000267422.7
ENST00000344429.5
ENST00000574031.1
ENST00000465357.2
ENST00000547619.1
neuro-oncological ventral antigen 1
chr7_-_107880508 0.28 ENST00000425651.2
neuronal cell adhesion molecule
chr17_+_43239191 0.26 ENST00000589230.1
hexamethylene bis-acetamide inducible 2
chr4_+_129732467 0.26 ENST00000413543.2
jade family PHD finger 1
chr7_+_139025875 0.25 ENST00000297534.6
chromosome 7 open reading frame 55
chr1_-_23886285 0.23 ENST00000374561.5
inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
chr9_+_116225999 0.21 ENST00000317613.6
regulator of G-protein signaling 3
chr11_-_31531121 0.21 ENST00000532287.1
ENST00000526776.1
ENST00000534812.1
ENST00000529749.1
ENST00000278200.1
ENST00000530023.1
ENST00000533642.1
IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr6_-_76203454 0.20 ENST00000237172.7
filamin A interacting protein 1
chr12_-_120241187 0.19 ENST00000392520.2
citron (rho-interacting, serine/threonine kinase 21)
chr12_+_107712173 0.19 ENST00000280758.5
ENST00000420571.2
BTB (POZ) domain containing 11
chr5_-_79950775 0.19 ENST00000439211.2
dihydrofolate reductase
chr10_+_94594351 0.18 ENST00000371552.4
exocyst complex component 6
chr4_-_105416039 0.18 ENST00000394767.2
CXXC finger protein 4
chr6_-_76203345 0.17 ENST00000393004.2
filamin A interacting protein 1
chr13_-_28545276 0.17 ENST00000381020.7
caudal type homeobox 2
chr17_-_46716647 0.17 ENST00000608940.1
RP11-357H14.17
chr8_+_107738343 0.17 ENST00000521592.1
oxidation resistance 1
chr17_-_202579 0.17 ENST00000577079.1
ENST00000331302.7
ENST00000536489.2
rabphilin 3A-like (without C2 domains)
chrX_-_153602991 0.16 ENST00000369850.3
ENST00000422373.1
filamin A, alpha
chr11_+_7618413 0.16 ENST00000528883.1
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr4_+_169418195 0.15 ENST00000261509.6
ENST00000335742.7
palladin, cytoskeletal associated protein
chr12_-_102591604 0.14 ENST00000329406.4
pro-melanin-concentrating hormone
chr3_-_9834463 0.14 ENST00000439043.1
transcriptional adaptor 3
chr12_-_12674032 0.14 ENST00000298573.4
dual specificity phosphatase 16
chrX_+_55478538 0.14 ENST00000342972.1
melanoma antigen family H, 1
chr11_-_3859089 0.13 ENST00000396979.1
ras homolog family member G
chr10_-_33405600 0.13 ENST00000414308.1
RP11-342D11.3
chr19_+_48949030 0.13 ENST00000253237.5
glutamate-rich WD repeat containing 1
chr7_-_81635106 0.13 ENST00000443883.1
calcium channel, voltage-dependent, alpha 2/delta subunit 1
chr14_+_65453432 0.13 ENST00000246166.2
farnesyltransferase, CAAX box, beta
chr2_-_145277569 0.13 ENST00000303660.4
zinc finger E-box binding homeobox 2
chr11_-_124981475 0.12 ENST00000532156.1
ENST00000532407.1
ENST00000279968.4
ENST00000527766.1
ENST00000529583.1
ENST00000524373.1
ENST00000527271.1
ENST00000526175.1
ENST00000529609.1
ENST00000533273.1
ENST00000531909.1
ENST00000529530.1
transmembrane protein 218
chrX_-_46187069 0.11 ENST00000446884.1
RP1-30G7.2
chr6_+_126221034 0.11 ENST00000433571.1
nuclear receptor coactivator 7
chr7_+_148982396 0.11 ENST00000418158.2
zinc finger family member 783
chr8_+_107738240 0.11 ENST00000449762.2
ENST00000297447.6
oxidation resistance 1
chr8_+_31496809 0.10 ENST00000518104.1
ENST00000519301.1
neuregulin 1
chr17_+_68100989 0.10 ENST00000585558.1
ENST00000392670.1
potassium inwardly-rectifying channel, subfamily J, member 16
chr4_+_105828537 0.10 ENST00000515649.1
RP11-556I14.1
chr3_-_27764190 0.10 ENST00000537516.1
eomesodermin
chr22_-_40929812 0.10 ENST00000422851.1
megakaryoblastic leukemia (translocation) 1
chr1_+_153746683 0.10 ENST00000271857.2
solute carrier family 27 (fatty acid transporter), member 3
chr6_+_43968306 0.09 ENST00000442114.2
ENST00000336600.5
ENST00000439969.2
chromosome 6 open reading frame 223
chr17_-_48785216 0.09 ENST00000285243.6
ankyrin repeat domain 40
chr1_+_186265399 0.09 ENST00000367486.3
ENST00000367484.3
ENST00000533951.1
ENST00000367482.4
ENST00000367483.4
ENST00000367485.4
ENST00000445192.2
proteoglycan 4
chr19_+_48949087 0.09 ENST00000598711.1
glutamate-rich WD repeat containing 1
chr12_-_51611477 0.09 ENST00000389243.4
POU class 6 homeobox 1
chr17_+_47448102 0.08 ENST00000576461.1
Uncharacterized protein
chr17_+_17685422 0.08 ENST00000395774.1
retinoic acid induced 1
chr2_-_164592497 0.08 ENST00000333129.3
ENST00000409634.1
fidgetin
chr11_+_46722368 0.08 ENST00000311764.2
zinc finger protein 408
chr9_+_133539981 0.08 ENST00000253008.2
PR domain containing 12
chr3_+_9834227 0.08 ENST00000287613.7
ENST00000397261.3
actin related protein 2/3 complex, subunit 4, 20kDa
chr5_+_61874562 0.07 ENST00000334994.5
ENST00000409534.1
leucine rich repeat containing 70
importin 11
chr2_+_45168875 0.07 ENST00000260653.3
SIX homeobox 3
chr17_+_59489112 0.07 ENST00000335108.2
chromosome 17 open reading frame 82
chr12_-_122017542 0.07 ENST00000446152.2
lysine (K)-specific demethylase 2B
chr4_+_169418255 0.07 ENST00000505667.1
ENST00000511948.1
palladin, cytoskeletal associated protein
chr17_-_7307358 0.07 ENST00000576017.1
ENST00000302422.3
ENST00000535512.1
transmembrane protein 256
TMEM256-PLSCR3 readthrough (NMD candidate)
chr12_-_122018346 0.07 ENST00000377069.4
lysine (K)-specific demethylase 2B
chrX_+_135730297 0.07 ENST00000370629.2
CD40 ligand
chr3_+_32859510 0.06 ENST00000383763.5
tripartite motif containing 71, E3 ubiquitin protein ligase
chr4_-_84035905 0.06 ENST00000311507.4
placenta-specific 8
chr12_-_57328187 0.06 ENST00000293502.1
short chain dehydrogenase/reductase family 9C, member 7
chr17_+_68101117 0.06 ENST00000587698.1
ENST00000587892.1
potassium inwardly-rectifying channel, subfamily J, member 16
chr6_-_97731019 0.06 ENST00000275053.4
MMS22-like, DNA repair protein
chr4_+_105828492 0.06 ENST00000506148.1
RP11-556I14.1
chrX_-_130423240 0.06 ENST00000370910.1
ENST00000370901.4
immunoglobulin superfamily, member 1
chr5_+_60933634 0.06 ENST00000505642.1
chromosome 5 open reading frame 64
chr17_+_39845134 0.06 ENST00000591776.1
ENST00000469257.1
eukaryotic translation initiation factor 1
chr19_-_46088068 0.05 ENST00000263275.4
ENST00000323060.3
optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
chr4_-_84035868 0.05 ENST00000426923.2
ENST00000509973.1
placenta-specific 8
chr12_+_8666126 0.05 ENST00000299665.2
C-type lectin domain family 4, member D
chr18_-_24237339 0.05 ENST00000580191.1
potassium channel tetramerization domain containing 1
chr4_-_122148620 0.05 ENST00000509841.1
TNFAIP3 interacting protein 3
chr4_-_138453606 0.05 ENST00000412923.2
ENST00000344876.4
ENST00000507846.1
ENST00000510305.1
protocadherin 18
chr18_+_29171689 0.05 ENST00000237014.3
transthyretin
chr1_+_41174988 0.05 ENST00000372652.1
nuclear transcription factor Y, gamma
chr11_-_64684672 0.05 ENST00000377264.3
ENST00000421419.2
autophagy related 2A
chr12_-_101604185 0.05 ENST00000536262.2
solute carrier family 5 (sodium/monocarboxylate cotransporter), member 8
chr12_-_86650045 0.05 ENST00000604798.1
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr19_-_49622348 0.04 ENST00000408991.2
chromosome 19 open reading frame 73
chr6_-_161695074 0.04 ENST00000457520.2
ENST00000366906.5
ENST00000320285.4
1-acylglycerol-3-phosphate O-acyltransferase 4
chr1_-_232651312 0.04 ENST00000262861.4
signal-induced proliferation-associated 1 like 2
chr1_+_62439037 0.04 ENST00000545929.1
InaD-like (Drosophila)
chr16_-_51185149 0.04 ENST00000566102.1
ENST00000541611.1
spalt-like transcription factor 1
chrX_+_123097014 0.04 ENST00000394478.1
stromal antigen 2
chr8_+_92261516 0.04 ENST00000276609.3
ENST00000309536.2
solute carrier family 26 (anion exchanger), member 7
chrX_-_130423200 0.04 ENST00000361420.3
immunoglobulin superfamily, member 1
chr3_+_9834179 0.04 ENST00000498623.2
actin related protein 2/3 complex, subunit 4, 20kDa
chrX_+_135730373 0.04 ENST00000370628.2
CD40 ligand
chr9_+_136501478 0.04 ENST00000393056.2
ENST00000263611.2
dopamine beta-hydroxylase (dopamine beta-monooxygenase)
chr1_-_190446759 0.04 ENST00000367462.3
bone morphogenetic protein/retinoic acid inducible neural-specific 3
chr16_-_67517716 0.03 ENST00000290953.2
agouti related protein homolog (mouse)
chr2_-_224467093 0.03 ENST00000305409.2
secretogranin II
chr7_+_120628731 0.03 ENST00000310396.5
cadherin-like and PC-esterase domain containing 1
chr14_+_32798547 0.03 ENST00000557354.1
ENST00000557102.1
ENST00000557272.1
A kinase (PRKA) anchor protein 6
chr17_-_39203519 0.03 ENST00000542137.1
ENST00000391419.3
keratin associated protein 2-1
chr7_-_78400598 0.03 ENST00000536571.1
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr6_+_101846664 0.03 ENST00000421544.1
ENST00000413795.1
ENST00000369138.1
ENST00000358361.3
glutamate receptor, ionotropic, kainate 2
chr5_-_142780280 0.03 ENST00000424646.2
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr4_-_176733377 0.03 ENST00000505375.1
glycoprotein M6A
chr6_+_152011628 0.03 ENST00000404742.1
ENST00000440973.1
estrogen receptor 1
chr6_+_114178512 0.03 ENST00000368635.4
myristoylated alanine-rich protein kinase C substrate
chr10_-_56561022 0.03 ENST00000373965.2
ENST00000414778.1
ENST00000395438.1
ENST00000409834.1
ENST00000395445.1
ENST00000395446.1
ENST00000395442.1
ENST00000395440.1
ENST00000395432.2
ENST00000361849.3
ENST00000395433.1
ENST00000320301.6
ENST00000395430.1
ENST00000437009.1
protocadherin-related 15
chr1_+_226411319 0.02 ENST00000542034.1
ENST00000366810.5
Mix paired-like homeobox
chr2_+_135596106 0.02 ENST00000356140.5
aminocarboxymuconate semialdehyde decarboxylase
chr1_+_244515930 0.02 ENST00000366537.1
ENST00000308105.4
chromosome 1 open reading frame 100
chrX_-_21676442 0.02 ENST00000379499.2
kelch-like family member 34
chr18_+_13465008 0.02 ENST00000593236.1
low density lipoprotein receptor class A domain containing 4
chr16_+_73420942 0.02 ENST00000554640.1
ENST00000562661.1
ENST00000561875.1
RP11-140I24.1
chr5_+_61874696 0.02 ENST00000491184.2
leucine rich repeat containing 70
chr16_-_51185172 0.02 ENST00000251020.4
spalt-like transcription factor 1
chr1_+_162351503 0.02 ENST00000458626.2
chromosome 1 open reading frame 226
chr2_+_135596180 0.02 ENST00000283054.4
ENST00000392928.1
aminocarboxymuconate semialdehyde decarboxylase
chr6_-_139613269 0.02 ENST00000358430.3
taxilin beta
chr2_-_145188137 0.02 ENST00000440875.1
zinc finger E-box binding homeobox 2
chr1_-_67600639 0.02 ENST00000544837.1
ENST00000603691.1
chromosome 1 open reading frame 141
chr8_-_109799793 0.02 ENST00000297459.3
transmembrane protein 74
chr1_+_40713573 0.02 ENST00000372766.3
transmembrane and coiled-coil domains 2
chr8_+_97773202 0.01 ENST00000519484.1
carboxypeptidase Q
chr12_-_86650077 0.01 ENST00000552808.2
ENST00000547225.1
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr12_-_122018114 0.01 ENST00000539394.1
lysine (K)-specific demethylase 2B
chr5_-_130500922 0.01 ENST00000513012.1
ENST00000508488.1
ENST00000506908.1
ENST00000304043.5
histidine triad nucleotide binding protein 1
chr3_-_157221380 0.01 ENST00000468233.1
ventricular zone expressed PH domain-containing 1
chr1_+_153747746 0.01 ENST00000368661.3
solute carrier family 27 (fatty acid transporter), member 3
chr1_+_43291220 0.01 ENST00000372514.3
erythroblast membrane-associated protein (Scianna blood group)
chr12_+_48722763 0.01 ENST00000335017.1
H1 histone family, member N, testis-specific
chr8_+_97773457 0.01 ENST00000521142.1
carboxypeptidase Q
chr15_+_54305101 0.01 ENST00000260323.11
ENST00000545554.1
ENST00000537900.1
unc-13 homolog C (C. elegans)
chr2_-_166060382 0.01 ENST00000409101.3
sodium channel, voltage-gated, type III, alpha subunit
chr3_+_130569429 0.01 ENST00000505330.1
ENST00000504381.1
ENST00000507488.2
ENST00000393221.4
ATPase, Ca++ transporting, type 2C, member 1
chr11_-_117170403 0.01 ENST00000504995.1
beta-site APP-cleaving enzyme 1
chr6_+_167704838 0.01 ENST00000366829.2
unc-93 homolog A (C. elegans)
chr15_+_34261089 0.01 ENST00000383263.5
cholinergic receptor, muscarinic 5
chr10_+_74451883 0.01 ENST00000373053.3
ENST00000357157.6
mitochondrial calcium uniporter
chr8_-_7220490 0.01 ENST00000400078.2
zinc finger protein 705G
chr6_-_161695042 0.00 ENST00000366908.5
ENST00000366911.5
ENST00000366905.3
1-acylglycerol-3-phosphate O-acyltransferase 4
chr4_-_168155169 0.00 ENST00000534949.1
ENST00000535728.1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr16_+_69985083 0.00 ENST00000288040.6
ENST00000449317.2
C-type lectin domain family 18, member A
chr12_-_6233828 0.00 ENST00000572068.1
ENST00000261405.5
von Willebrand factor
chr2_+_226265364 0.00 ENST00000272907.6
neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2
chr2_+_203776937 0.00 ENST00000402905.3
ENST00000414490.1
ENST00000431787.1
ENST00000444724.1
ENST00000414857.1
ENST00000430899.1
ENST00000445120.1
ENST00000441569.1
ENST00000432024.1
ENST00000443740.1
ENST00000414439.1
ENST00000428585.1
ENST00000545253.1
ENST00000545262.1
ENST00000447539.1
ENST00000456821.2
ENST00000434998.1
ENST00000320443.8
calcium responsive transcription factor
chr6_+_167704798 0.00 ENST00000230256.3
unc-93 homolog A (C. elegans)
chr4_+_71458012 0.00 ENST00000449493.2
ameloblastin (enamel matrix protein)
chr12_+_126107042 0.00 ENST00000535886.1
transmembrane protein 132B

Network of associatons between targets according to the STRING database.

First level regulatory network of VENTX

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0060585 nitric oxide transport(GO:0030185) negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.1 0.3 GO:0052651 monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.1 0.5 GO:0070092 regulation of glucagon secretion(GO:0070092)
0.1 0.2 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.1 0.7 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.2 GO:0046452 dihydrofolate metabolic process(GO:0046452)
0.0 0.1 GO:0045209 MAPK phosphatase export from nucleus(GO:0045208) MAPK phosphatase export from nucleus, leptomycin B sensitive(GO:0045209)
0.0 0.2 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.2 GO:0021993 initiation of neural tube closure(GO:0021993)
0.0 0.1 GO:0014016 neuroblast differentiation(GO:0014016)
0.0 0.2 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.1 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.1 GO:1900111 positive regulation of histone H3-K9 dimethylation(GO:1900111)
0.0 0.2 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.3 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.7 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.1 GO:0060809 mesodermal to mesenchymal transition involved in gastrulation(GO:0060809)
0.0 0.1 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.0 0.1 GO:0086048 membrane depolarization during bundle of His cell action potential(GO:0086048)
0.0 0.1 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.0 0.4 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.0 0.6 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736)
0.0 0.1 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.0 0.4 GO:1903204 negative regulation of oxidative stress-induced neuron death(GO:1903204)
0.0 0.1 GO:0061034 olfactory bulb mitral cell layer development(GO:0061034)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.1 0.2 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 0.7 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.4 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 0.2 GO:0031523 Myb complex(GO:0031523)
0.0 0.1 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.0 0.1 GO:0035101 FACT complex(GO:0035101)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.6 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.1 GO:0086057 voltage-gated calcium channel activity involved in bundle of His cell action potential(GO:0086057)
0.0 0.1 GO:0005174 CD40 receptor binding(GO:0005174)
0.0 0.1 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.0 0.2 GO:0051870 methotrexate binding(GO:0051870)
0.0 0.2 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.0 0.3 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.2 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.1 GO:0034711 inhibin binding(GO:0034711)
0.0 0.3 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 PID EPHRINB REV PATHWAY Ephrin B reverse signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.7 REACTOME INCRETIN SYNTHESIS SECRETION AND INACTIVATION Genes involved in Incretin Synthesis, Secretion, and Inactivation
0.0 0.7 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions