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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for ZBTB12

Z-value: 1.33

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Transcription factors associated with ZBTB12

Gene Symbol Gene ID Gene Info
ZBTB12
ENSG00000204366.3 zinc finger and BTB domain containing 12

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZBTB12hg19_v2_chr6_-_31869769_31869880-0.883.2e-07Click!

Activity profile of ZBTB12 motif

Sorted Z-values of ZBTB12 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chrX_-_73072534 7.37 ENST00000429829.1
XIST
X inactive specific transcript (non-protein coding)
chr17_-_39677971 6.70 ENST00000393976.2
KRT15
keratin 15
chr1_+_158979792 6.50 ENST00000359709.3
ENST00000430894.2
IFI16
interferon, gamma-inducible protein 16
chr1_+_158979686 6.07 ENST00000368132.3
ENST00000295809.7
IFI16
interferon, gamma-inducible protein 16
chr1_+_158979680 5.97 ENST00000368131.4
ENST00000340979.6
IFI16
interferon, gamma-inducible protein 16
chr1_+_35220613 4.63 ENST00000338513.1
GJB5
gap junction protein, beta 5, 31.1kDa
chr19_+_52873166 4.34 ENST00000424032.2
ENST00000600321.1
ENST00000344085.5
ENST00000597976.1
ENST00000422689.2
ZNF880
zinc finger protein 880
chr19_-_11688500 4.05 ENST00000433365.2
ACP5
acid phosphatase 5, tartrate resistant
chr6_+_36097992 4.01 ENST00000211287.4
MAPK13
mitogen-activated protein kinase 13
chr17_-_5487768 3.81 ENST00000269280.4
ENST00000345221.3
ENST00000262467.5
NLRP1
NLR family, pyrin domain containing 1
chr6_+_18387570 3.46 ENST00000259939.3
RNF144B
ring finger protein 144B
chr10_+_5454505 3.24 ENST00000355029.4
NET1
neuroepithelial cell transforming 1
chr22_+_38035459 3.21 ENST00000357436.4
SH3BP1
SH3-domain binding protein 1
chr19_-_51531210 3.21 ENST00000391804.3
KLK11
kallikrein-related peptidase 11
chr11_-_104972158 3.20 ENST00000598974.1
ENST00000593315.1
ENST00000594519.1
ENST00000415981.2
ENST00000525374.1
ENST00000375707.1
CASP1
CARD16
CARD17
caspase 1, apoptosis-related cysteine peptidase
caspase recruitment domain family, member 16
caspase recruitment domain family, member 17
chr4_-_140477353 2.83 ENST00000406354.1
ENST00000506866.2
SETD7
SET domain containing (lysine methyltransferase) 7
chr11_-_104905840 2.82 ENST00000526568.1
ENST00000393136.4
ENST00000531166.1
ENST00000534497.1
ENST00000527979.1
ENST00000446369.1
ENST00000353247.5
ENST00000528974.1
ENST00000533400.1
ENST00000525825.1
ENST00000436863.3
CASP1
caspase 1, apoptosis-related cysteine peptidase
chr19_-_51531272 2.74 ENST00000319720.7
KLK11
kallikrein-related peptidase 11
chr19_-_51530916 2.69 ENST00000594768.1
KLK11
kallikrein-related peptidase 11
chr6_-_114292449 2.67 ENST00000519065.1
HDAC2
histone deacetylase 2
chr2_-_214013353 2.67 ENST00000451136.2
ENST00000421754.2
ENST00000374327.4
ENST00000413091.3
IKZF2
IKAROS family zinc finger 2 (Helios)
chr14_-_21270995 2.61 ENST00000555698.1
ENST00000397970.4
ENST00000340900.3
RNASE1
ribonuclease, RNase A family, 1 (pancreatic)
chr19_-_36019123 2.50 ENST00000588674.1
ENST00000452271.2
ENST00000518157.1
SBSN
suprabasin
chr8_-_42360015 2.34 ENST00000522707.1
SLC20A2
solute carrier family 20 (phosphate transporter), member 2
chr4_+_185734773 2.08 ENST00000508020.1
RP11-701P16.2
Uncharacterized protein
chr8_+_38758737 1.94 ENST00000521746.1
ENST00000420274.1
PLEKHA2
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
chr10_-_12084770 1.92 ENST00000357604.5
UPF2
UPF2 regulator of nonsense transcripts homolog (yeast)
chr18_-_57364588 1.86 ENST00000439986.4
CCBE1
collagen and calcium binding EGF domains 1
chr13_-_37633743 1.86 ENST00000497318.1
ENST00000475892.1
ENST00000356185.3
ENST00000350612.6
ENST00000542180.1
ENST00000360252.4
SUPT20H
suppressor of Ty 20 homolog (S. cerevisiae)
chr4_-_99851766 1.83 ENST00000450253.2
EIF4E
eukaryotic translation initiation factor 4E
chr7_-_27169801 1.82 ENST00000511914.1
HOXA4
homeobox A4
chr4_-_36246060 1.81 ENST00000303965.4
ARAP2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr12_+_14572070 1.81 ENST00000545769.1
ENST00000428217.2
ENST00000396279.2
ENST00000542514.1
ENST00000536279.1
ATF7IP
activating transcription factor 7 interacting protein
chr7_+_134430212 1.73 ENST00000436461.2
CALD1
caldesmon 1
chr1_+_151009035 1.72 ENST00000368931.3
BNIPL
BCL2/adenovirus E1B 19kD interacting protein like
chr10_-_98273668 1.69 ENST00000357947.3
TLL2
tolloid-like 2
chr1_+_201755452 1.55 ENST00000438083.1
NAV1
neuron navigator 1
chr1_+_151009054 1.52 ENST00000295294.7
BNIPL
BCL2/adenovirus E1B 19kD interacting protein like
chr13_+_45694583 1.50 ENST00000340473.6
GTF2F2
general transcription factor IIF, polypeptide 2, 30kDa
chr11_+_8704748 1.47 ENST00000526562.1
ENST00000525981.1
RPL27A
ribosomal protein L27a
chr11_-_61124776 1.46 ENST00000542361.1
CYB561A3
cytochrome b561 family, member A3
chr4_-_140477910 1.44 ENST00000404104.3
SETD7
SET domain containing (lysine methyltransferase) 7
chr6_-_170599561 1.43 ENST00000366756.3
DLL1
delta-like 1 (Drosophila)
chr4_-_87028478 1.34 ENST00000515400.1
ENST00000395157.3
MAPK10
mitogen-activated protein kinase 10
chr19_-_6767431 1.33 ENST00000437152.3
ENST00000597687.1
SH2D3A
SH2 domain containing 3A
chr11_-_2170786 1.24 ENST00000300632.5
IGF2
insulin-like growth factor 2 (somatomedin A)
chr18_-_32870148 1.22 ENST00000589178.1
ENST00000333206.5
ENST00000592278.1
ENST00000592211.1
ENST00000420878.3
ENST00000383091.2
ENST00000586922.2
ZSCAN30
RP11-158H5.7
zinc finger and SCAN domain containing 30
RP11-158H5.7
chr6_+_26158343 1.21 ENST00000377777.4
ENST00000289316.2
HIST1H2BD
histone cluster 1, H2bd
chr14_+_67707826 1.19 ENST00000261681.4
MPP5
membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
chr19_+_58258164 1.17 ENST00000317178.5
ZNF776
zinc finger protein 776
chr19_-_11688951 1.13 ENST00000589792.1
ACP5
acid phosphatase 5, tartrate resistant
chr19_-_46148820 1.10 ENST00000587152.1
EML2
echinoderm microtubule associated protein like 2
chr6_+_147527103 1.09 ENST00000179882.6
STXBP5
syntaxin binding protein 5 (tomosyn)
chr22_-_36236623 1.08 ENST00000405409.2
RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr4_-_87515202 1.08 ENST00000502302.1
ENST00000513186.1
MAPK10
mitogen-activated protein kinase 10
chr5_-_122372354 1.05 ENST00000306442.4
PPIC
peptidylprolyl isomerase C (cyclophilin C)
chr6_-_52926539 1.03 ENST00000350082.5
ENST00000356971.3
ICK
intestinal cell (MAK-like) kinase
chr13_+_97928395 1.03 ENST00000445661.2
MBNL2
muscleblind-like splicing regulator 2
chr16_+_31724552 1.02 ENST00000539915.1
ENST00000316491.9
ENST00000399681.3
ENST00000398696.3
ENST00000534369.1
ZNF720
zinc finger protein 720
chr3_+_101818088 1.01 ENST00000491959.1
ZPLD1
zona pellucida-like domain containing 1
chr1_-_117210290 1.01 ENST00000369483.1
ENST00000369486.3
IGSF3
immunoglobulin superfamily, member 3
chr17_-_4643161 0.97 ENST00000574412.1
CXCL16
chemokine (C-X-C motif) ligand 16
chr9_-_26946981 0.96 ENST00000523212.1
PLAA
phospholipase A2-activating protein
chr4_-_68995571 0.96 ENST00000356291.2
TMPRSS11F
transmembrane protease, serine 11F
chr12_-_133532864 0.95 ENST00000536932.1
ENST00000360187.4
ENST00000392321.3
CHFR
ZNF605
checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase
zinc finger protein 605
chr1_-_32264356 0.92 ENST00000452755.2
SPOCD1
SPOC domain containing 1
chr9_-_80437915 0.89 ENST00000397476.3
GNAQ
guanine nucleotide binding protein (G protein), q polypeptide
chr14_+_76618242 0.89 ENST00000557542.1
ENST00000557263.1
ENST00000557207.1
ENST00000312858.5
ENST00000261530.7
GPATCH2L
G patch domain containing 2-like
chr15_-_49912987 0.89 ENST00000560246.1
ENST00000558594.1
FAM227B
family with sequence similarity 227, member B
chr11_+_12132117 0.88 ENST00000256194.4
MICAL2
microtubule associated monooxygenase, calponin and LIM domain containing 2
chr8_+_104892639 0.85 ENST00000436393.2
RIMS2
regulating synaptic membrane exocytosis 2
chr8_-_6115044 0.84 ENST00000519555.1
RP11-124B13.1
RP11-124B13.1
chr16_+_31724618 0.83 ENST00000530881.1
ENST00000529515.1
ZNF720
zinc finger protein 720
chr13_-_46716969 0.80 ENST00000435666.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr1_+_61869748 0.79 ENST00000357977.5
NFIA
nuclear factor I/A
chr16_-_30134441 0.78 ENST00000395200.1
MAPK3
mitogen-activated protein kinase 3
chr10_+_180643 0.77 ENST00000509513.2
ENST00000397959.3
ZMYND11
zinc finger, MYND-type containing 11
chrX_+_70338525 0.77 ENST00000374102.1
MED12
mediator complex subunit 12
chr4_-_10118348 0.76 ENST00000502702.1
WDR1
WD repeat domain 1
chr1_+_32757668 0.75 ENST00000373548.3
HDAC1
histone deacetylase 1
chr16_+_66914264 0.75 ENST00000311765.2
ENST00000568869.1
ENST00000561704.1
ENST00000568398.1
ENST00000566776.1
PDP2
pyruvate dehyrogenase phosphatase catalytic subunit 2
chr19_-_6767516 0.69 ENST00000245908.6
SH2D3A
SH2 domain containing 3A
chr8_-_141728760 0.68 ENST00000430260.2
PTK2
protein tyrosine kinase 2
chr13_+_42712178 0.68 ENST00000536612.1
DGKH
diacylglycerol kinase, eta
chr1_+_100598691 0.68 ENST00000370143.1
ENST00000370141.2
TRMT13
tRNA methyltransferase 13 homolog (S. cerevisiae)
chr1_+_100503643 0.68 ENST00000370152.3
HIAT1
hippocampus abundant transcript 1
chr12_+_95612006 0.67 ENST00000551311.1
ENST00000546445.1
VEZT
vezatin, adherens junctions transmembrane protein
chr18_-_47018769 0.65 ENST00000583637.1
ENST00000578528.1
ENST00000578532.1
ENST00000580387.1
ENST00000579248.1
ENST00000581373.1
RPL17
ribosomal protein L17
chr3_+_185080908 0.63 ENST00000265026.3
MAP3K13
mitogen-activated protein kinase kinase kinase 13
chr11_-_62323702 0.63 ENST00000530285.1
AHNAK
AHNAK nucleoprotein
chr3_-_50336548 0.62 ENST00000450489.1
ENST00000513170.1
ENST00000450982.1
NAT6
HYAL3
N-acetyltransferase 6 (GCN5-related)
hyaluronoglucosaminidase 3
chr10_-_54215029 0.61 ENST00000435813.2
RP11-346D6.6
RP11-346D6.6
chr15_-_35280426 0.61 ENST00000559564.1
ENST00000356321.4
ZNF770
zinc finger protein 770
chr12_-_122884553 0.60 ENST00000535290.1
CLIP1
CAP-GLY domain containing linker protein 1
chr5_+_148443049 0.57 ENST00000515304.1
ENST00000507318.1
CTC-529P8.1
CTC-529P8.1
chr22_-_42084863 0.57 ENST00000401959.1
ENST00000355257.3
NHP2L1
NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae)
chr13_+_49822041 0.56 ENST00000538056.1
ENST00000251108.6
ENST00000444959.1
ENST00000429346.1
CDADC1
cytidine and dCMP deaminase domain containing 1
chr18_-_53177984 0.56 ENST00000543082.1
TCF4
transcription factor 4
chr5_-_148929848 0.54 ENST00000504676.1
ENST00000515435.1
CSNK1A1
casein kinase 1, alpha 1
chr3_+_49236910 0.54 ENST00000452691.2
ENST00000366429.2
CCDC36
coiled-coil domain containing 36
chr4_+_26859300 0.53 ENST00000494628.2
STIM2
stromal interaction molecule 2
chr3_-_72149553 0.53 ENST00000468646.2
ENST00000464271.1
LINC00877
long intergenic non-protein coding RNA 877
chr5_+_150406527 0.53 ENST00000520059.1
GPX3
glutathione peroxidase 3 (plasma)
chr17_+_11501748 0.51 ENST00000262442.4
ENST00000579828.1
DNAH9
dynein, axonemal, heavy chain 9
chr1_-_94344754 0.51 ENST00000436063.2
DNTTIP2
deoxynucleotidyltransferase, terminal, interacting protein 2
chr3_-_50336826 0.51 ENST00000443842.1
ENST00000354862.4
ENST00000443094.2
ENST00000415204.1
ENST00000336307.1
NAT6
HYAL3
N-acetyltransferase 6 (GCN5-related)
hyaluronoglucosaminidase 3
chr5_-_88179017 0.49 ENST00000514028.1
ENST00000514015.1
ENST00000503075.1
ENST00000437473.2
MEF2C
myocyte enhancer factor 2C
chr17_-_7142725 0.48 ENST00000571362.1
ENST00000576955.1
ENST00000320316.3
PHF23
PHD finger protein 23
chr8_-_33330595 0.46 ENST00000524021.1
ENST00000335589.3
FUT10
fucosyltransferase 10 (alpha (1,3) fucosyltransferase)
chr1_+_26644441 0.45 ENST00000374213.2
CD52
CD52 molecule
chr17_-_7518145 0.44 ENST00000250113.7
ENST00000571597.1
FXR2
fragile X mental retardation, autosomal homolog 2
chr4_-_140477928 0.43 ENST00000274031.3
SETD7
SET domain containing (lysine methyltransferase) 7
chr22_+_18121356 0.41 ENST00000317582.5
ENST00000543133.1
ENST00000538149.1
ENST00000337612.5
ENST00000493680.1
BCL2L13
BCL2-like 13 (apoptosis facilitator)
chr3_-_52804872 0.40 ENST00000535191.1
ENST00000461689.1
ENST00000383721.4
ENST00000233027.5
NEK4
NIMA-related kinase 4
chr11_-_65769594 0.38 ENST00000532707.1
ENST00000533544.1
ENST00000526451.1
ENST00000312234.2
ENST00000530462.1
ENST00000525767.1
ENST00000529964.1
ENST00000527249.1
EIF1AD
eukaryotic translation initiation factor 1A domain containing
chr8_-_141728444 0.38 ENST00000521562.1
PTK2
protein tyrosine kinase 2
chr10_+_180405 0.37 ENST00000439456.1
ENST00000397962.3
ENST00000309776.4
ENST00000381602.4
ZMYND11
zinc finger, MYND-type containing 11
chr15_-_55562451 0.35 ENST00000568803.1
RAB27A
RAB27A, member RAS oncogene family
chr12_+_49208234 0.33 ENST00000540990.1
CACNB3
calcium channel, voltage-dependent, beta 3 subunit
chr2_+_166152283 0.33 ENST00000375427.2
SCN2A
sodium channel, voltage-gated, type II, alpha subunit
chr7_+_92158083 0.33 ENST00000265732.5
ENST00000481551.1
ENST00000496410.1
RBM48
RNA binding motif protein 48
chr13_+_46039037 0.32 ENST00000349995.5
COG3
component of oligomeric golgi complex 3
chr12_-_123215306 0.32 ENST00000356987.2
ENST00000436083.2
HCAR1
hydroxycarboxylic acid receptor 1
chr14_-_74960030 0.32 ENST00000553490.1
ENST00000557510.1
NPC2
Niemann-Pick disease, type C2
chrX_-_122866874 0.31 ENST00000245838.8
ENST00000355725.4
THOC2
THO complex 2
chrX_-_24690771 0.31 ENST00000379145.1
PCYT1B
phosphate cytidylyltransferase 1, choline, beta
chr1_+_11838988 0.30 ENST00000444493.1
C1orf167
chromosome 1 open reading frame 167
chr5_-_88178964 0.30 ENST00000513252.1
ENST00000508569.1
ENST00000510942.1
ENST00000506554.1
MEF2C
myocyte enhancer factor 2C
chr1_+_22778337 0.29 ENST00000404138.1
ENST00000400239.2
ENST00000375647.4
ENST00000374651.4
ZBTB40
zinc finger and BTB domain containing 40
chr12_-_46766577 0.28 ENST00000256689.5
SLC38A2
solute carrier family 38, member 2
chr7_-_142247606 0.28 ENST00000390361.3
TRBV7-3
T cell receptor beta variable 7-3
chr19_+_44716768 0.28 ENST00000586048.1
ZNF227
zinc finger protein 227
chr1_-_94344686 0.27 ENST00000528680.1
DNTTIP2
deoxynucleotidyltransferase, terminal, interacting protein 2
chr8_-_30670384 0.25 ENST00000221138.4
ENST00000518243.1
PPP2CB
protein phosphatase 2, catalytic subunit, beta isozyme
chr6_-_31782813 0.25 ENST00000375654.4
HSPA1L
heat shock 70kDa protein 1-like
chr16_-_30134524 0.24 ENST00000395202.1
ENST00000395199.3
ENST00000263025.4
ENST00000322266.5
ENST00000403394.1
MAPK3
mitogen-activated protein kinase 3
chr17_-_46178527 0.23 ENST00000393408.3
CBX1
chromobox homolog 1
chr20_+_2854066 0.22 ENST00000455631.1
ENST00000216877.6
ENST00000399903.2
ENST00000358719.4
ENST00000431048.1
ENST00000425918.2
ENST00000430705.1
ENST00000318266.5
PTPRA
protein tyrosine phosphatase, receptor type, A
chr12_-_123459105 0.22 ENST00000543935.1
ABCB9
ATP-binding cassette, sub-family B (MDR/TAP), member 9
chr5_+_148786423 0.22 ENST00000505254.2
ENST00000602964.1
ENST00000519898.1
MIR143HG
MIR143 host gene (non-protein coding)
chr12_-_62586543 0.22 ENST00000416284.3
FAM19A2
family with sequence similarity 19 (chemokine (C-C motif)-like), member A2
chr7_+_129984630 0.22 ENST00000355388.3
ENST00000497503.1
ENST00000463587.1
ENST00000461828.1
ENST00000494311.1
ENST00000466363.2
ENST00000485477.1
ENST00000431780.2
ENST00000474905.1
CPA5
carboxypeptidase A5
chr4_-_40632605 0.21 ENST00000514014.1
RBM47
RNA binding motif protein 47
chr15_-_34880646 0.20 ENST00000543376.1
GOLGA8A
golgin A8 family, member A
chrX_-_131353461 0.20 ENST00000370874.1
RAP2C
RAP2C, member of RAS oncogene family
chr2_+_173600514 0.19 ENST00000264111.6
RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr10_+_23217006 0.18 ENST00000376528.4
ENST00000447081.1
ARMC3
armadillo repeat containing 3
chr22_-_50523843 0.18 ENST00000535444.1
ENST00000431262.2
MLC1
megalencephalic leukoencephalopathy with subcortical cysts 1
chr7_+_23637763 0.17 ENST00000410069.1
CCDC126
coiled-coil domain containing 126
chr8_+_1993173 0.16 ENST00000523438.1
MYOM2
myomesin 2
chr11_+_74303612 0.16 ENST00000527458.1
ENST00000532497.1
ENST00000530511.1
POLD3
polymerase (DNA-directed), delta 3, accessory subunit
chr22_-_25335502 0.16 ENST00000423535.1
TMEM211
transmembrane protein 211
chrX_+_133371077 0.15 ENST00000517294.1
ENST00000370809.4
CCDC160
coiled-coil domain containing 160
chr11_-_18063973 0.14 ENST00000528338.1
TPH1
tryptophan hydroxylase 1
chr3_-_52097567 0.13 ENST00000541313.1
LINC00696
long intergenic non-protein coding RNA 696
chr10_+_52152766 0.13 ENST00000596442.1
AC069547.2
Uncharacterized protein
chr5_+_36606700 0.12 ENST00000416645.2
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr11_+_112047087 0.12 ENST00000526088.1
ENST00000532593.1
ENST00000531169.1
BCO2
beta-carotene oxygenase 2
chr14_-_96743060 0.12 ENST00000554299.1
DKFZP434O1614
DKFZP434O1614
chr8_+_1993152 0.11 ENST00000262113.4
MYOM2
myomesin 2
chr4_-_40632757 0.11 ENST00000511902.1
ENST00000505220.1
RBM47
RNA binding motif protein 47
chr1_-_152779104 0.10 ENST00000606576.1
ENST00000368768.1
LCE1C
late cornified envelope 1C
chr22_-_50523807 0.09 ENST00000442311.1
ENST00000538737.1
MLC1
megalencephalic leukoencephalopathy with subcortical cysts 1
chr2_+_128405655 0.09 ENST00000423019.1
GPR17
G protein-coupled receptor 17
chr11_-_68611721 0.08 ENST00000561996.1
CPT1A
carnitine palmitoyltransferase 1A (liver)
chr11_+_65769946 0.08 ENST00000533166.1
BANF1
barrier to autointegration factor 1
chr11_+_64323098 0.08 ENST00000301891.4
SLC22A11
solute carrier family 22 (organic anion/urate transporter), member 11
chr1_+_100598742 0.08 ENST00000370139.1
TRMT13
tRNA methyltransferase 13 homolog (S. cerevisiae)
chr9_+_127615733 0.07 ENST00000373574.1
WDR38
WD repeat domain 38
chr12_-_70004942 0.07 ENST00000361484.3
LRRC10
leucine rich repeat containing 10
chr11_+_111126707 0.07 ENST00000280325.4
C11orf53
chromosome 11 open reading frame 53
chr5_-_156772729 0.06 ENST00000312349.4
FNDC9
fibronectin type III domain containing 9
chr5_-_88179302 0.05 ENST00000504921.2
MEF2C
myocyte enhancer factor 2C
chr19_+_44716678 0.04 ENST00000586228.1
ENST00000588219.1
ENST00000313040.7
ENST00000589707.1
ENST00000588394.1
ENST00000589005.1
ZNF227
zinc finger protein 227
chr1_+_150229554 0.04 ENST00000369111.4
CA14
carbonic anhydrase XIV
chr3_-_196242233 0.03 ENST00000397537.2
SMCO1
single-pass membrane protein with coiled-coil domains 1
chr7_-_138347897 0.03 ENST00000288513.5
SVOPL
SVOP-like
chr10_+_23216944 0.02 ENST00000298032.5
ENST00000409983.3
ENST00000409049.3
ARMC3
armadillo repeat containing 3
chr11_+_63273547 0.02 ENST00000255684.5
ENST00000394618.3
LGALS12
lectin, galactoside-binding, soluble, 12
chr22_-_50524298 0.02 ENST00000311597.5
MLC1
megalencephalic leukoencephalopathy with subcortical cysts 1

Network of associatons between targets according to the STRING database.

First level regulatory network of ZBTB12

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 6.0 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
1.3 3.8 GO:1904784 NLRP1 inflammasome complex assembly(GO:1904784)
0.9 4.6 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.6 5.2 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.6 3.1 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
0.5 3.2 GO:0040009 regulation of growth rate(GO:0040009)
0.4 3.4 GO:0061198 fungiform papilla formation(GO:0061198)
0.4 1.2 GO:0035750 protein localization to myelin sheath abaxonal region(GO:0035750)
0.3 1.0 GO:2000656 regulation of apolipoprotein binding(GO:2000656) negative regulation of apolipoprotein binding(GO:2000657)
0.3 4.7 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.3 1.9 GO:1901490 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748) regulation of lymphangiogenesis(GO:1901490)
0.3 18.5 GO:0032731 positive regulation of interleukin-1 beta production(GO:0032731)
0.2 0.9 GO:0019417 sulfur oxidation(GO:0019417)
0.2 1.0 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.2 0.8 GO:0016334 morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247)
0.2 0.5 GO:0060629 regulation of homologous chromosome segregation(GO:0060629)
0.2 3.2 GO:0051451 myoblast migration(GO:0051451)
0.2 2.4 GO:0007258 JUN phosphorylation(GO:0007258)
0.1 2.3 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.1 0.8 GO:0003172 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.1 1.2 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.1 1.0 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.1 0.8 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.1 0.5 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.1 1.0 GO:0032808 lacrimal gland development(GO:0032808)
0.1 0.6 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.1 1.5 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.1 0.5 GO:0006982 response to lipid hydroperoxide(GO:0006982)
0.1 1.1 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.1 0.9 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.1 0.9 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.1 1.1 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.1 0.5 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.1 1.8 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.1 1.1 GO:0034243 regulation of transcription elongation from RNA polymerase II promoter(GO:0034243)
0.1 1.1 GO:0071493 cellular response to UV-B(GO:0071493)
0.1 1.0 GO:0010818 T cell chemotaxis(GO:0010818)
0.0 0.5 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.1 GO:0042214 terpene metabolic process(GO:0042214)
0.0 0.7 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.0 6.7 GO:0070268 cornification(GO:0070268)
0.0 0.3 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.0 1.0 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.0 0.3 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.0 0.8 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 3.5 GO:0032755 positive regulation of interleukin-6 production(GO:0032755)
0.0 0.5 GO:0042354 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 0.8 GO:0072189 ureter development(GO:0072189)
0.0 0.2 GO:0035672 oligopeptide transmembrane transport(GO:0035672)
0.0 1.8 GO:0071549 cellular response to dexamethasone stimulus(GO:0071549)
0.0 0.3 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.0 0.4 GO:0001302 replicative cell aging(GO:0001302)
0.0 0.3 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 2.6 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0 4.4 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.0 0.1 GO:0042427 serotonin biosynthetic process(GO:0042427)
0.0 0.3 GO:0032328 alanine transport(GO:0032328)
0.0 1.9 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.0 0.3 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 1.0 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 1.0 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 1.0 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.5 GO:0003341 cilium movement(GO:0003341)
0.0 1.9 GO:0031100 organ regeneration(GO:0031100)
0.0 0.5 GO:0045730 respiratory burst(GO:0045730)
0.0 0.7 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.1 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 1.6 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.1 GO:0070779 gamma-aminobutyric acid biosynthetic process(GO:0009449) D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.7 GO:0016337 single organismal cell-cell adhesion(GO:0016337)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 9.8 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.5 1.5 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.2 4.6 GO:0005922 connexon complex(GO:0005922)
0.2 0.8 GO:0042643 actomyosin, actin portion(GO:0042643)
0.1 1.7 GO:0030478 actin cap(GO:0030478)
0.1 1.8 GO:0033391 chromatoid body(GO:0033391)
0.1 1.9 GO:0000124 SAGA complex(GO:0000124)
0.1 3.4 GO:0016580 Sin3 complex(GO:0016580)
0.1 1.2 GO:0043219 lateral loop(GO:0043219)
0.1 1.9 GO:0035145 exon-exon junction complex(GO:0035145)
0.1 0.6 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.1 1.6 GO:0043194 axon initial segment(GO:0043194)
0.0 1.1 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 7.2 GO:0005882 intermediate filament(GO:0005882)
0.0 1.0 GO:0031143 pseudopodium(GO:0031143)
0.0 19.6 GO:0016607 nuclear speck(GO:0016607)
0.0 0.6 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.8 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.3 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.3 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 1.0 GO:0097546 ciliary base(GO:0097546)
0.0 0.2 GO:0001940 male pronucleus(GO:0001940)
0.0 0.3 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.9 GO:0000786 nucleosome(GO:0000786)
0.0 0.6 GO:0043034 costamere(GO:0043034)
0.0 1.6 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.9 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 1.9 GO:0005581 collagen trimer(GO:0005581)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 10.2 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.4 2.6 GO:0004522 ribonuclease A activity(GO:0004522)
0.3 1.0 GO:0016005 phospholipase A2 activator activity(GO:0016005)
0.3 5.2 GO:0008199 ferric iron binding(GO:0008199)
0.3 2.3 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.2 1.1 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.2 7.4 GO:0004707 MAP kinase activity(GO:0004707)
0.2 1.8 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.1 0.9 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.1 3.2 GO:0017049 GTP-Rho binding(GO:0017049)
0.1 1.5 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.1 0.7 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.1 3.4 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 1.4 GO:0030957 Tat protein binding(GO:0030957)
0.1 17.7 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 1.0 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 3.5 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.1 6.7 GO:0097110 scaffold protein binding(GO:0097110)
0.1 0.3 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 4.7 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.1 1.7 GO:0005523 tropomyosin binding(GO:0005523)
0.1 0.8 GO:0003680 AT DNA binding(GO:0003680)
0.0 1.1 GO:0008432 JUN kinase binding(GO:0008432)
0.0 1.9 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.5 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 11.3 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.2 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.0 0.1 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.0 0.9 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.5 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 1.9 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.2 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.6 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.1 GO:1990698 palmitoleoyltransferase activity(GO:1990698)
0.0 0.7 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.5 GO:0008430 selenium binding(GO:0008430)
0.0 1.2 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 1.8 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 1.0 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 1.1 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.2 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.5 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.7 GO:0017022 myosin binding(GO:0017022)
0.0 0.6 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 1.9 GO:0005518 collagen binding(GO:0005518)
0.0 2.0 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.8 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 3.2 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.3 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.1 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 1.1 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.3 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.8 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 10.7 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.2 4.0 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 0.9 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 2.4 ST ADRENERGIC Adrenergic Pathway
0.0 3.4 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 5.2 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.9 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 1.8 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.0 3.2 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 1.8 PID ARF6 PATHWAY Arf6 signaling events
0.0 1.9 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 1.4 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.6 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 0.7 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.6 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 1.2 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 3.5 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 6.0 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.2 3.8 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.2 4.6 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.2 4.0 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.1 3.4 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 1.4 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1 1.8 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.1 0.9 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 1.5 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.1 5.2 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 1.2 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 6.7 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.0 0.7 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 1.1 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 1.2 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.8 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 1.7 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.7 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 1.7 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.6 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.9 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 3.1 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 1.0 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 2.7 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.7 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis