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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for ZBTB18

Z-value: 1.03

Motif logo

Transcription factors associated with ZBTB18

Gene Symbol Gene ID Gene Info
ENSG00000179456.9 zinc finger and BTB domain containing 18

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZBTB18hg19_v2_chr1_+_244214577_244214593-0.934.4e-09Click!

Activity profile of ZBTB18 motif

Sorted Z-values of ZBTB18 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr8_-_49834299 5.66 ENST00000396822.1
snail family zinc finger 2
chr2_+_113885138 5.63 ENST00000409930.3
interleukin 1 receptor antagonist
chr8_-_49833978 5.57 ENST00000020945.1
snail family zinc finger 2
chr1_-_207206092 4.69 ENST00000359470.5
ENST00000461135.2
chromosome 1 open reading frame 116
chrX_+_43515467 3.42 ENST00000338702.3
ENST00000542639.1
monoamine oxidase A
chrX_+_99899180 3.35 ENST00000373004.3
sushi-repeat containing protein, X-linked 2
chr3_-_111314230 3.13 ENST00000317012.4
zinc finger, BED-type containing 2
chr19_-_36001286 2.87 ENST00000602679.1
ENST00000492341.2
ENST00000472252.2
ENST00000602781.1
ENST00000402589.2
ENST00000458071.1
ENST00000436012.1
ENST00000443640.1
ENST00000450261.1
ENST00000467637.1
ENST00000480502.1
ENST00000474928.1
ENST00000414866.2
ENST00000392206.2
ENST00000488892.1
dermokine
chr7_+_90225796 2.84 ENST00000380050.3
cyclin-dependent kinase 14
chr3_+_100211412 2.71 ENST00000323523.4
ENST00000403410.1
ENST00000449609.1
transmembrane protein 45A
chr10_-_123357598 2.59 ENST00000358487.5
ENST00000369058.3
ENST00000369060.4
ENST00000359354.2
fibroblast growth factor receptor 2
chr2_-_163099885 2.53 ENST00000443424.1
fibroblast activation protein, alpha
chr2_-_163100045 2.45 ENST00000188790.4
fibroblast activation protein, alpha
chr1_+_78354175 2.42 ENST00000401035.3
ENST00000457030.1
ENST00000330010.8
nexilin (F actin binding protein)
chr19_-_36001113 2.27 ENST00000434389.1
dermokine
chr10_+_11206925 2.27 ENST00000354440.2
ENST00000315874.4
ENST00000427450.1
CUGBP, Elav-like family member 2
chr1_+_78354330 2.26 ENST00000440324.1
nexilin (F actin binding protein)
chr1_+_78354243 2.18 ENST00000294624.8
nexilin (F actin binding protein)
chr1_+_78354297 2.13 ENST00000334785.7
nexilin (F actin binding protein)
chr10_-_105437909 2.08 ENST00000540321.1
SH3 and PX domains 2A
chr14_+_94577074 1.90 ENST00000444961.1
ENST00000448882.1
ENST00000557098.1
ENST00000554800.1
ENST00000556544.1
ENST00000298902.5
ENST00000555819.1
ENST00000557634.1
ENST00000555744.1
interferon, alpha-inducible protein 27
chr17_+_47653178 1.86 ENST00000328741.5
neurexophilin 3
chr14_-_61748550 1.84 ENST00000555868.1
transmembrane protein 30B
chr3_-_69590486 1.84 ENST00000497880.1
FERM domain containing 4B
chr12_-_54785074 1.80 ENST00000338010.5
ENST00000550774.1
zinc finger protein 385A
chr3_+_49840685 1.78 ENST00000333323.4
family with sequence similarity 212, member A
chr12_+_112563335 1.76 ENST00000549358.1
ENST00000257604.5
ENST00000548092.1
ENST00000552896.1
TRAF-type zinc finger domain containing 1
chr12_-_54785054 1.74 ENST00000352268.6
ENST00000549962.1
zinc finger protein 385A
chr15_+_49715449 1.73 ENST00000560979.1
fibroblast growth factor 7
chr12_+_112563303 1.65 ENST00000412615.2
TRAF-type zinc finger domain containing 1
chrX_-_153141302 1.63 ENST00000361699.4
ENST00000543994.1
ENST00000370057.3
ENST00000538883.1
ENST00000361981.3
L1 cell adhesion molecule
chr11_+_71900703 1.60 ENST00000393681.2
folate receptor 1 (adult)
chr17_+_47653471 1.55 ENST00000513748.1
neurexophilin 3
chr12_-_104443890 1.51 ENST00000547583.1
ENST00000360814.4
ENST00000546851.1
glycosyltransferase 8 domain containing 2
chr19_-_36001386 1.50 ENST00000461300.1
dermokine
chr19_+_50084561 1.50 ENST00000246794.5
proline rich Gla (G-carboxyglutamic acid) 2
chr8_-_11058847 1.46 ENST00000297303.4
ENST00000416569.2
XK, Kell blood group complex subunit-related family, member 6
chrX_-_30877837 1.46 ENST00000378930.3
TGF-beta activated kinase 1/MAP3K7 binding protein 3
chr19_+_9203855 1.44 ENST00000429566.3
olfactory receptor, family 1, subfamily M, member 1
chr1_+_38022513 1.42 ENST00000296218.7
dynein, axonemal, light intermediate chain 1
chr8_-_29592736 1.41 ENST00000518623.1
long intergenic non-protein coding RNA 589
chr8_+_104831472 1.41 ENST00000262231.10
ENST00000507740.1
regulating synaptic membrane exocytosis 2
chrX_+_9880412 1.41 ENST00000418909.2
shroom family member 2
chr4_+_75311019 1.40 ENST00000502307.1
amphiregulin
chrX_-_153141434 1.38 ENST00000407935.2
ENST00000439496.1
L1 cell adhesion molecule
chr12_+_1738363 1.35 ENST00000397196.2
wingless-type MMTV integration site family, member 5B
chr4_+_47487285 1.34 ENST00000273859.3
ENST00000504445.1
ATPase, class V, type 10D
chr1_+_38022572 1.31 ENST00000541606.1
dynein, axonemal, light intermediate chain 1
chr4_+_144312659 1.31 ENST00000509992.1
GRB2-associated binding protein 1
chr11_+_128562372 1.30 ENST00000344954.6
Fli-1 proto-oncogene, ETS transcription factor
chr11_+_94227129 1.29 ENST00000540349.1
ENST00000535502.1
ENST00000545130.1
ENST00000544253.1
ENST00000541144.1
ankyrin repeat domain 49
chr5_+_140792614 1.28 ENST00000398610.2
protocadherin gamma subfamily A, 10
chr17_+_42385927 1.22 ENST00000426726.3
ENST00000590941.1
ENST00000225441.7
RUN domain containing 3A
chr11_-_128894053 1.19 ENST00000392657.3
Rho GTPase activating protein 32
chr3_+_101659682 1.16 ENST00000465215.1
RP11-221J22.1
chr4_-_152149033 1.11 ENST00000514152.1
SH3 domain containing 19
chr4_+_75480629 1.09 ENST00000380846.3
amphiregulin B
chr11_+_59480899 1.08 ENST00000300150.7
syntaxin 3
chr4_+_75310851 1.04 ENST00000395748.3
ENST00000264487.2
amphiregulin
chrX_+_150151824 1.02 ENST00000455596.1
ENST00000448905.2
high mobility group box 3
chr21_+_30502806 1.01 ENST00000399928.1
ENST00000399926.1
MAP3K7 C-terminal like
chr19_+_48673949 1.01 ENST00000328759.7
chromosome 19 open reading frame 68
chr1_+_26856236 0.97 ENST00000374168.2
ENST00000374166.4
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr5_+_49962495 0.97 ENST00000515175.1
poly (ADP-ribose) polymerase family, member 8
chr11_-_57089671 0.96 ENST00000532437.1
tankyrase 1 binding protein 1, 182kDa
chr15_-_96590126 0.94 ENST00000561051.1
RP11-4G2.1
chr6_-_163148780 0.93 ENST00000366892.1
ENST00000366898.1
ENST00000366897.1
ENST00000366896.1
parkin RBR E3 ubiquitin protein ligase
chr12_-_54121261 0.93 ENST00000549784.1
ENST00000262059.4
calcium binding and coiled-coil domain 1
chr17_+_36584662 0.90 ENST00000431231.2
ENST00000437668.3
Rho GTPase activating protein 23
chr6_-_163148700 0.86 ENST00000366894.1
ENST00000338468.3
parkin RBR E3 ubiquitin protein ligase
chr1_+_37947257 0.84 ENST00000471012.1
zinc finger CCCH-type containing 12A
chr2_-_85829496 0.84 ENST00000409668.1
transmembrane protein 150A
chr19_+_9251052 0.84 ENST00000247956.6
ENST00000360385.3
zinc finger protein 317
chr9_+_72658490 0.76 ENST00000377182.4
MAM domain containing 2
chr7_+_100770328 0.76 ENST00000223095.4
ENST00000445463.2
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
chr1_+_19967014 0.74 ENST00000428975.1
neuroblastoma 1, DAN family BMP antagonist
chr11_-_5537920 0.74 ENST00000380184.1
ubiquilin-like
chr14_+_67707826 0.74 ENST00000261681.4
membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
chr12_-_50222187 0.74 ENST00000335999.6
NCK-associated protein 5-like
chr3_-_105588231 0.73 ENST00000545639.1
ENST00000394027.3
ENST00000438603.1
ENST00000447441.1
ENST00000443752.1
Cbl proto-oncogene B, E3 ubiquitin protein ligase
chr12_-_56121612 0.73 ENST00000546939.1
CD63 molecule
chr8_-_37411648 0.71 ENST00000519738.1
RP11-150O12.1
chrX_+_150151752 0.70 ENST00000325307.7
high mobility group box 3
chr5_+_140782351 0.70 ENST00000573521.1
protocadherin gamma subfamily A, 9
chr6_-_30523865 0.68 ENST00000433809.1
guanine nucleotide binding protein-like 1
chr2_-_163099546 0.66 ENST00000447386.1
fibroblast activation protein, alpha
chr3_-_178789220 0.65 ENST00000414084.1
zinc finger, matrin-type 3
chr8_+_104831554 0.64 ENST00000408894.2
regulating synaptic membrane exocytosis 2
chr2_-_85829780 0.64 ENST00000334462.5
transmembrane protein 150A
chr4_-_87855851 0.63 ENST00000473559.1
chromosome 4 open reading frame 36
chr15_-_43559055 0.62 ENST00000220420.5
ENST00000349114.4
transglutaminase 5
chr1_-_2458026 0.61 ENST00000435556.3
ENST00000378466.3
pantothenate kinase 4
chr2_-_85829811 0.60 ENST00000306353.3
transmembrane protein 150A
chr3_-_37216055 0.59 ENST00000336686.4
leucine rich repeat (in FLII) interacting protein 2
chr3_+_124303512 0.58 ENST00000454902.1
kalirin, RhoGEF kinase
chr11_-_33722286 0.58 ENST00000451594.2
ENST00000379011.4
chromosome 11 open reading frame 91
chr10_-_95241951 0.57 ENST00000358334.5
ENST00000359263.4
ENST00000371488.3
myoferlin
chr12_-_56122124 0.56 ENST00000552754.1
CD63 molecule
chr6_+_163148973 0.55 ENST00000366888.2
PARK2 co-regulated
chrX_+_9880590 0.55 ENST00000452575.1
shroom family member 2
chr17_-_41174424 0.52 ENST00000355653.3
vesicle amine transport 1
chr10_-_7829909 0.51 ENST00000379562.4
ENST00000543003.1
ENST00000535925.1
KIN, antigenic determinant of recA protein homolog (mouse)
chr10_-_104913367 0.51 ENST00000423468.2
5'-nucleotidase, cytosolic II
chr16_+_67563250 0.51 ENST00000566907.1
family with sequence similarity 65, member A
chr13_-_33780133 0.50 ENST00000399365.3
StAR-related lipid transfer (START) domain containing 13
chr5_-_149324306 0.49 ENST00000255266.5
phosphodiesterase 6A, cGMP-specific, rod, alpha
chr11_+_15136462 0.48 ENST00000379556.3
ENST00000424273.1
inscuteable homolog (Drosophila)
chr8_-_73793975 0.46 ENST00000523881.1
RP11-1145L24.1
chr11_-_62323702 0.45 ENST00000530285.1
AHNAK nucleoprotein
chr10_+_105253661 0.44 ENST00000369780.4
neuralized E3 ubiquitin protein ligase 1
chr8_+_104831440 0.43 ENST00000515551.1
regulating synaptic membrane exocytosis 2
chr3_-_44552094 0.43 ENST00000436261.1
zinc finger protein 852
chr1_+_9005917 0.42 ENST00000549778.1
ENST00000480186.3
ENST00000377443.2
ENST00000377436.3
ENST00000377442.2
carbonic anhydrase VI
chrX_-_48056199 0.40 ENST00000311798.1
ENST00000347757.1
synovial sarcoma, X breakpoint 5
chr12_-_56122220 0.40 ENST00000552692.1
CD63 molecule
chr1_+_32608566 0.40 ENST00000545542.1
karyopherin alpha 6 (importin alpha 7)
chr12_-_56121580 0.40 ENST00000550776.1
CD63 molecule
chr11_-_63684316 0.39 ENST00000301459.4
REST corepressor 2
chr7_+_97361218 0.38 ENST00000319273.5
tachykinin, precursor 1
chr9_+_87283430 0.37 ENST00000376214.1
ENST00000376213.1
neurotrophic tyrosine kinase, receptor, type 2
chr12_+_53846594 0.37 ENST00000550192.1
poly(rC) binding protein 2
chrX_+_48242863 0.37 ENST00000376886.2
ENST00000375517.3
synovial sarcoma, X breakpoint 4
chrX_-_77225135 0.37 ENST00000458128.1
phosphoglycerate mutase family member 4
chr11_-_119252425 0.36 ENST00000260187.2
ubiquitin specific peptidase 2
chr2_-_74692473 0.34 ENST00000535045.1
ENST00000409065.1
ENST00000414701.1
ENST00000448666.1
ENST00000233616.4
ENST00000452063.2
mannosyl-oligosaccharide glucosidase
chr10_-_95242044 0.33 ENST00000371501.4
ENST00000371502.4
ENST00000371489.1
myoferlin
chr2_+_33359687 0.33 ENST00000402934.1
ENST00000404525.1
ENST00000407925.1
latent transforming growth factor beta binding protein 1
chr12_+_53846612 0.33 ENST00000551104.1
poly(rC) binding protein 2
chr9_-_13165457 0.31 ENST00000542239.1
ENST00000538841.1
ENST00000433359.2
multiple PDZ domain protein
chr8_+_38965048 0.31 ENST00000399831.3
ENST00000437682.2
ENST00000519315.1
ENST00000379907.4
ENST00000522506.1
ADAM metallopeptidase domain 32
chr9_+_273038 0.30 ENST00000487230.1
ENST00000469391.1
dedicator of cytokinesis 8
chr12_+_27619743 0.27 ENST00000298876.4
ENST00000416383.1
single-pass membrane protein with coiled-coil domains 2
chr18_+_6834472 0.27 ENST00000581099.1
ENST00000419673.2
ENST00000531294.1
Rho GTPase activating protein 28
chr2_+_33359646 0.26 ENST00000390003.4
ENST00000418533.2
latent transforming growth factor beta binding protein 1
chr1_+_53527854 0.26 ENST00000371500.3
ENST00000395871.2
ENST00000312553.5
podocan
chr7_+_120969045 0.25 ENST00000222462.2
wingless-type MMTV integration site family, member 16
chrX_-_153141783 0.24 ENST00000458029.1
L1 cell adhesion molecule
chr15_-_31453359 0.23 ENST00000542188.1
transient receptor potential cation channel, subfamily M, member 1
chr6_-_74363803 0.23 ENST00000355773.5
solute carrier family 17 (acidic sugar transporter), member 5
chr1_-_113160826 0.23 ENST00000538187.1
ENST00000369664.1
suppression of tumorigenicity 7 like
chr5_+_159895275 0.22 ENST00000517927.1
microRNA 146a
chr3_+_159570722 0.22 ENST00000482804.1
schwannomin interacting protein 1
chr9_+_2029019 0.22 ENST00000382194.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr3_+_124303539 0.22 ENST00000428018.2
kalirin, RhoGEF kinase
chr2_-_69064324 0.21 ENST00000415448.1
AC097495.3
chr5_-_151304337 0.21 ENST00000455880.2
ENST00000545569.1
ENST00000274576.4
glycine receptor, alpha 1
chr9_+_127023704 0.20 ENST00000373596.1
ENST00000425237.1
NIMA-related kinase 6
chr12_+_77718388 0.19 ENST00000550042.1
RP1-34H18.1
chr3_+_124303472 0.19 ENST00000291478.5
kalirin, RhoGEF kinase
chr10_+_97733786 0.19 ENST00000371198.2
coiled-coil and C2 domain containing 2B
chr2_-_230096756 0.18 ENST00000354069.6
phosphotyrosine interaction domain containing 1
chr18_+_54814288 0.18 ENST00000585477.1
biorientation of chromosomes in cell division 1-like 2
chr9_+_125551150 0.17 ENST00000373680.2
olfactory receptor, family 5, subfamily C, member 1
chr17_+_75369167 0.17 ENST00000423034.2
septin 9
chr5_-_142784888 0.17 ENST00000514699.1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr14_+_38033252 0.16 ENST00000554829.1
RP11-356O9.1
chr20_+_30467600 0.15 ENST00000375934.4
ENST00000375922.4
tubulin tyrosine ligase-like family, member 9
chrY_-_21239221 0.15 ENST00000447937.1
ENST00000331787.2
testis-specific transcript, Y-linked 14 (non-protein coding)
chr19_+_39903185 0.15 ENST00000409794.3
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chr11_+_32154200 0.14 ENST00000525133.1
RP1-65P5.5
chr16_+_24266874 0.14 ENST00000005284.3
calcium channel, voltage-dependent, gamma subunit 3
chr1_-_99470368 0.13 ENST00000263177.4
Lipid phosphate phosphatase-related protein type 5
chr19_-_15918936 0.12 ENST00000334920.2
olfactory receptor, family 10, subfamily H, member 1
chr15_-_74043816 0.12 ENST00000379822.4
chromosome 15 open reading frame 59
chr15_+_47631257 0.12 ENST00000560636.1
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
chr2_-_159237472 0.12 ENST00000409187.1
coiled-coil domain containing 148
chr7_+_97361388 0.12 ENST00000350485.4
ENST00000346867.4
tachykinin, precursor 1
chrX_+_64808248 0.11 ENST00000609672.1
moesin
chr13_-_46964177 0.11 ENST00000389908.3
KIAA0226-like
chr19_+_11649532 0.11 ENST00000252456.2
ENST00000592923.1
ENST00000535659.2
calponin 1, basic, smooth muscle
chrX_-_154563889 0.10 ENST00000369449.2
ENST00000321926.4
chloride intracellular channel 2
chr17_-_62050278 0.10 ENST00000578147.1
ENST00000435607.1
sodium channel, voltage-gated, type IV, alpha subunit
chr4_-_100009856 0.10 ENST00000296412.8
alcohol dehydrogenase 5 (class III), chi polypeptide
chr1_+_211433275 0.10 ENST00000367005.4
REST corepressor 3
chr9_+_125137565 0.10 ENST00000373698.5
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr17_+_32907768 0.10 ENST00000321639.5
transmembrane protein 132E
chr1_-_247275719 0.10 ENST00000408893.2
chromosome 1 open reading frame 229
chr21_-_35883541 0.10 ENST00000399284.1
potassium voltage-gated channel, Isk-related family, member 1
chr22_-_37213554 0.09 ENST00000443735.1
parvalbumin
chr10_-_48050538 0.09 ENST00000420079.2
N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2C
chr15_+_57210818 0.09 ENST00000438423.2
ENST00000267811.5
ENST00000452095.2
ENST00000559609.1
ENST00000333725.5
transcription factor 12
chr2_+_33359473 0.08 ENST00000432635.1
latent transforming growth factor beta binding protein 1
chr3_+_121311966 0.08 ENST00000338040.4
F-box protein 40
chr8_+_24241789 0.07 ENST00000256412.4
ENST00000538205.1
ADAM-like, decysin 1
chr11_-_1606513 0.07 ENST00000382171.2
keratin associated protein 5-1
chr17_-_33885117 0.06 ENST00000415846.3
schlafen family member 14
chrX_+_123480194 0.06 ENST00000371139.4
SH2 domain containing 1A
chr17_-_41174367 0.06 ENST00000587173.1
vesicle amine transport 1
chr11_+_4470525 0.05 ENST00000325719.4
olfactory receptor, family 52, subfamily K, member 2
chr11_-_57089774 0.05 ENST00000527207.1
tankyrase 1 binding protein 1, 182kDa
chr11_+_5775923 0.04 ENST00000317254.3
olfactory receptor, family 52, subfamily N, member 4 (gene/pseudogene)
chr11_-_101454658 0.04 ENST00000344327.3
transient receptor potential cation channel, subfamily C, member 6
chr1_-_217262933 0.03 ENST00000359162.2
estrogen-related receptor gamma
chr8_+_24241969 0.03 ENST00000522298.1
ADAM-like, decysin 1
chr9_-_35870461 0.03 ENST00000377981.2
olfactory receptor, family 13, subfamily J, member 1
chr15_+_51669444 0.03 ENST00000396399.2
gliomedin
chr8_+_1772132 0.03 ENST00000349830.3
ENST00000520359.1
ENST00000518288.1
ENST00000398560.1
Rho guanine nucleotide exchange factor (GEF) 10
chr3_+_183894566 0.03 ENST00000439647.1
adaptor-related protein complex 2, mu 1 subunit
chr1_-_99470558 0.02 ENST00000370188.3
Lipid phosphate phosphatase-related protein type 5
chr3_+_183894737 0.02 ENST00000432591.1
ENST00000431779.1
adaptor-related protein complex 2, mu 1 subunit

Network of associatons between targets according to the STRING database.

First level regulatory network of ZBTB18

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.7 11.2 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
1.9 5.6 GO:1902362 melanocyte apoptotic process(GO:1902362)
0.9 6.6 GO:1903575 cornified envelope assembly(GO:1903575)
0.9 2.6 GO:0035604 fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604) fibroblast growth factor receptor signaling pathway involved in mammary gland specification(GO:0060595) mammary gland bud formation(GO:0060615) branch elongation involved in salivary gland morphogenesis(GO:0060667) mesenchymal cell differentiation involved in lung development(GO:0060915)
0.7 2.0 GO:0008057 eye pigment granule organization(GO:0008057)
0.6 5.6 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.5 1.6 GO:0003147 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713)
0.5 3.5 GO:1902162 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.4 9.0 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.3 2.1 GO:0072674 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.3 0.8 GO:2000625 regulation of miRNA catabolic process(GO:2000625) positive regulation of miRNA catabolic process(GO:2000627)
0.3 0.8 GO:0001300 chronological cell aging(GO:0001300)
0.2 0.7 GO:0035750 protein localization to myelin sheath abaxonal region(GO:0035750)
0.2 2.4 GO:0060744 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.2 1.3 GO:0060437 lung growth(GO:0060437)
0.2 3.4 GO:0042420 dopamine catabolic process(GO:0042420)
0.2 2.5 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.2 3.4 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.2 0.5 GO:2000854 positive regulation of corticosterone secretion(GO:2000854)
0.1 0.7 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.1 1.9 GO:0035826 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.1 1.0 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.1 1.1 GO:0098881 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.1 1.0 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
0.1 0.3 GO:0061485 memory T cell proliferation(GO:0061485)
0.1 0.4 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.1 1.8 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.1 1.3 GO:0070307 lens fiber cell development(GO:0070307)
0.1 0.5 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.1 0.6 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.1 0.2 GO:0003408 optic cup formation involved in camera-type eye development(GO:0003408)
0.1 0.3 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.1 0.4 GO:0099538 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551)
0.1 0.7 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.1 0.9 GO:0001778 plasma membrane repair(GO:0001778)
0.1 0.9 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.1 1.1 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 1.3 GO:0035855 megakaryocyte development(GO:0035855)
0.0 1.9 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.2 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 1.3 GO:0045332 phospholipid translocation(GO:0045332)
0.0 2.3 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.2 GO:2001170 positive regulation of fat cell proliferation(GO:0070346) negative regulation of ATP biosynthetic process(GO:2001170)
0.0 0.1 GO:0046294 formaldehyde catabolic process(GO:0046294)
0.0 2.5 GO:0045824 negative regulation of innate immune response(GO:0045824)
0.0 0.7 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.0 1.9 GO:0046825 regulation of protein export from nucleus(GO:0046825)
0.0 0.7 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.5 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 3.0 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 1.3 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.0 1.0 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.0 1.8 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 1.5 GO:0002755 MyD88-dependent toll-like receptor signaling pathway(GO:0002755)
0.0 0.2 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.3 GO:0045475 locomotor rhythm(GO:0045475)
0.0 1.7 GO:0032392 DNA geometric change(GO:0032392)
0.0 0.3 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.5 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.0 2.1 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 1.2 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.7 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 1.4 GO:0000271 polysaccharide biosynthetic process(GO:0000271)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.8 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.3 5.6 GO:0071438 invadopodium membrane(GO:0071438)
0.3 1.1 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.1 1.9 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.1 0.8 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1 3.2 GO:0044295 axonal growth cone(GO:0044295)
0.1 0.2 GO:0035841 new growing cell tip(GO:0035841)
0.1 1.6 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.7 GO:0043219 lateral loop(GO:0043219)
0.0 2.5 GO:0048786 presynaptic active zone(GO:0048786)
0.0 2.7 GO:0030286 dynein complex(GO:0030286)
0.0 1.0 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 8.9 GO:0030018 Z disc(GO:0030018)
0.0 2.1 GO:0002102 podosome(GO:0002102)
0.0 15.5 GO:0000790 nuclear chromatin(GO:0000790)
0.0 2.4 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.7 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.6 GO:0097225 sperm midpiece(GO:0097225)
0.0 1.9 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 8.6 GO:0060076 excitatory synapse(GO:0060076)
0.0 0.2 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.4 GO:0043034 costamere(GO:0043034)
0.0 0.7 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.5 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 2.0 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.4 GO:0097228 sperm principal piece(GO:0097228)
0.0 4.0 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.1 GO:0031143 pseudopodium(GO:0031143)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 5.6 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.4 1.6 GO:0061714 folic acid receptor activity(GO:0061714)
0.4 3.4 GO:0008131 primary amine oxidase activity(GO:0008131)
0.2 2.6 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.2 5.6 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.2 0.5 GO:0050146 nucleoside phosphotransferase activity(GO:0050146)
0.1 2.7 GO:0045504 dynein heavy chain binding(GO:0045504)
0.1 2.1 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 0.7 GO:0050436 microfibril binding(GO:0050436)
0.1 2.0 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.1 0.9 GO:0010853 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.1 0.3 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 1.1 GO:0050544 arachidonic acid binding(GO:0050544)
0.1 0.4 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.1 1.0 GO:0071532 ankyrin repeat binding(GO:0071532)
0.1 0.7 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.1 0.6 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 8.8 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 0.7 GO:0016015 morphogen activity(GO:0016015)
0.1 0.4 GO:0060175 brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.1 1.7 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 2.9 GO:0030332 cyclin binding(GO:0030332)
0.0 9.7 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.9 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 1.9 GO:0005521 lamin binding(GO:0005521)
0.0 1.3 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.6 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.4 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 2.4 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.2 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.8 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 1.3 GO:0042056 chemoattractant activity(GO:0042056)
0.0 2.3 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 4.2 GO:0002039 p53 binding(GO:0002039)
0.0 1.6 GO:0005109 frizzled binding(GO:0005109)
0.0 0.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 1.0 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.1 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.0 1.0 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.3 GO:0015926 glucosidase activity(GO:0015926)
0.0 0.6 GO:0030275 LRR domain binding(GO:0030275)
0.0 1.1 GO:0030291 protein serine/threonine kinase inhibitor activity(GO:0030291)
0.0 0.5 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 1.3 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.0 2.6 GO:0019838 growth factor binding(GO:0019838)
0.0 0.7 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 1.2 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.6 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.1 GO:0031433 telethonin binding(GO:0031433)
0.0 1.0 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 11.8 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1 5.0 PID IL1 PATHWAY IL1-mediated signaling events
0.1 2.4 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 3.2 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 3.6 PID FGF PATHWAY FGF signaling pathway
0.0 1.0 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 1.8 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 4.3 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 1.8 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 0.7 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.5 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.9 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.9 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.1 3.4 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1 1.5 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.1 5.0 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.1 3.4 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 1.1 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 1.3 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.5 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.4 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 1.3 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 1.0 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 1.9 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 1.1 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.7 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 2.6 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 1.3 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.3 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.0 1.1 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.7 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.5 REACTOME CGMP EFFECTS Genes involved in cGMP effects