Project

SARS-CoV-2 Analysis Results (GEO series: GSE147507)

Navigation
Downloads

Results for ZFHX3

Z-value: 0.56

Motif logo

Transcription factors associated with ZFHX3

Gene Symbol Gene ID Gene Info
ENSG00000140836.10 zinc finger homeobox 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZFHX3hg19_v2_chr16_-_73093597_730935970.252.9e-01Click!

Activity profile of ZFHX3 motif

Sorted Z-values of ZFHX3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_155511887 3.01 ENST00000302053.3
ENST00000403106.3
fibrinogen alpha chain
chr22_-_30970560 2.52 ENST00000402369.1
ENST00000406361.1
galactose-3-O-sulfotransferase 1
chr17_-_64225508 1.93 ENST00000205948.6
apolipoprotein H (beta-2-glycoprotein I)
chr19_-_36304201 1.93 ENST00000301175.3
proline dehydrogenase (oxidase) 2
chr11_+_71934962 1.84 ENST00000543234.1
inositol polyphosphate phosphatase-like 1
chr9_-_123812542 1.79 ENST00000223642.1
complement component 5
chr17_-_26697304 1.78 ENST00000536498.1
vitronectin
chr22_-_30970498 1.43 ENST00000431313.1
galactose-3-O-sulfotransferase 1
chr8_-_145754428 1.24 ENST00000527462.1
ENST00000313465.5
ENST00000524821.1
chromosome 8 open reading frame 82
chr11_-_61687739 1.13 ENST00000531922.1
ENST00000301773.5
RAB3A interacting protein (rabin3)-like 1
chr19_-_58864848 1.10 ENST00000263100.3
alpha-1-B glycoprotein
chr17_+_4692230 1.09 ENST00000331264.7
glycolipid transfer protein domain containing 2
chr20_-_33735070 1.00 ENST00000374491.3
ENST00000542871.1
ENST00000374492.3
ER degradation enhancer, mannosidase alpha-like 2
chr11_-_559377 0.95 ENST00000486629.1
chromosome 11 open reading frame 35
chrX_-_110655306 0.90 ENST00000371993.2
doublecortin
chrX_-_15288154 0.85 ENST00000380483.3
ENST00000380485.3
ENST00000380488.4
ankyrin repeat and SOCS box containing 9
chr19_+_50016610 0.82 ENST00000596975.1
Fc fragment of IgG, receptor, transporter, alpha
chr19_+_54466179 0.79 ENST00000270458.2
calcium channel, voltage-dependent, gamma subunit 8
chr12_+_54410664 0.60 ENST00000303406.4
homeobox C4
chr20_+_42187682 0.59 ENST00000373092.3
ENST00000373077.1
serum/glucocorticoid regulated kinase 2
chr19_-_46234119 0.57 ENST00000317683.3
F-box protein 46
chr14_-_54425475 0.53 ENST00000559642.1
bone morphogenetic protein 4
chr16_+_87636474 0.52 ENST00000284262.2
junctophilin 3
chr7_+_130126012 0.51 ENST00000341441.5
mesoderm specific transcript
chr20_+_42187608 0.43 ENST00000373100.1
serum/glucocorticoid regulated kinase 2
chr2_-_87248975 0.42 ENST00000409310.2
ENST00000355705.3
plasminogen-like B1
chr17_-_26733179 0.41 ENST00000440501.1
ENST00000321666.5
solute carrier family 46 (folate transporter), member 1
chr7_-_7575477 0.39 ENST00000399429.3
collagen, type XXVIII, alpha 1
chr7_+_130126165 0.36 ENST00000427521.1
ENST00000416162.2
ENST00000378576.4
mesoderm specific transcript
chrX_-_18690210 0.36 ENST00000379984.3
retinoschisin 1
chr17_-_39156138 0.35 ENST00000391587.1
keratin associated protein 3-2
chr3_-_114477787 0.34 ENST00000464560.1
zinc finger and BTB domain containing 20
chr7_+_150725510 0.34 ENST00000461373.1
ENST00000358849.4
ENST00000297504.6
ENST00000542328.1
ENST00000498578.1
ENST00000356058.4
ENST00000477719.1
ENST00000477092.1
ATP-binding cassette, sub-family B (MDR/TAP), member 8
chr2_+_105050794 0.34 ENST00000429464.1
ENST00000414442.1
ENST00000447380.1
long intergenic non-protein coding RNA 1102
chr3_+_35722424 0.30 ENST00000396481.2
cAMP-regulated phosphoprotein, 21kDa
chr22_-_30642728 0.29 ENST00000403987.3
leukemia inhibitory factor
chr3_+_35722487 0.28 ENST00000441454.1
cAMP-regulated phosphoprotein, 21kDa
chr5_+_60933634 0.28 ENST00000505642.1
chromosome 5 open reading frame 64
chr2_+_133174147 0.28 ENST00000329321.3
G protein-coupled receptor 39
chr15_+_76352178 0.24 ENST00000388942.3
chromosome 15 open reading frame 27
chr14_+_39703112 0.24 ENST00000555143.1
ENST00000280082.3
melanoma inhibitory activity 2
chr11_-_74800799 0.22 ENST00000305159.3
olfactory receptor, family 2, subfamily AT, member 4
chr3_+_77088989 0.22 ENST00000461745.1
roundabout, axon guidance receptor, homolog 2 (Drosophila)
chrM_+_9207 0.21 ENST00000362079.2
mitochondrially encoded cytochrome c oxidase III
chr11_+_8040739 0.20 ENST00000534099.1
tubby bipartite transcription factor
chr12_+_53835508 0.19 ENST00000551003.1
ENST00000549068.1
ENST00000549740.1
ENST00000546581.1
ENST00000549581.1
ENST00000541275.1
proline rich 13
poly(rC) binding protein 2
chr5_+_140625147 0.19 ENST00000231173.3
protocadherin beta 15
chr2_+_190541153 0.19 ENST00000313581.4
ENST00000438402.2
ENST00000431575.2
ENST00000281412.6
ankyrin and armadillo repeat containing
chr1_+_170632250 0.18 ENST00000367760.3
paired related homeobox 1
chrM_+_10053 0.16 ENST00000361227.2
mitochondrially encoded NADH dehydrogenase 3
chrX_+_9431324 0.16 ENST00000407597.2
ENST00000424279.1
ENST00000536365.1
ENST00000441088.1
ENST00000380961.1
ENST00000415293.1
transducin (beta)-like 1X-linked
chr12_+_131438443 0.16 ENST00000261654.5
G protein-coupled receptor 133
chr6_-_116447283 0.16 ENST00000452729.1
ENST00000243222.4
collagen, type X, alpha 1
chr6_-_152793728 0.16 ENST00000495090.2
spectrin repeat containing, nuclear envelope 1
chr19_+_926000 0.16 ENST00000263620.3
AT rich interactive domain 3A (BRIGHT-like)
chr7_+_100026406 0.16 ENST00000414441.1
methylphosphate capping enzyme
chr8_+_98900132 0.15 ENST00000520016.1
matrilin 2
chr14_-_83262540 0.15 ENST00000554451.1
RP11-11K13.1
chr7_+_48211048 0.15 ENST00000435803.1
ATP-binding cassette, sub-family A (ABC1), member 13
chr22_-_30722912 0.15 ENST00000215790.7
TBC1 domain family, member 10A
chr12_-_2944184 0.14 ENST00000337508.4
nuclear receptor interacting protein 2
chr6_-_31681839 0.14 ENST00000409239.1
ENST00000461287.1
lymphocyte antigen 6 complex, locus G6E (pseudogene)
Uncharacterized protein
chr12_-_11184006 0.13 ENST00000390675.2
taste receptor, type 2, member 31
chr2_-_40680578 0.13 ENST00000455476.1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr20_-_21494654 0.13 ENST00000377142.4
NK2 homeobox 2
chrY_-_20935572 0.13 ENST00000382852.1
ENST00000344884.4
ENST00000304790.3
heat shock transcription factor, Y linked 2
chr6_+_161123270 0.12 ENST00000366924.2
ENST00000308192.9
ENST00000418964.1
plasminogen
chr6_+_25754927 0.12 ENST00000377905.4
ENST00000439485.2
solute carrier family 17, member 4
chr4_-_68829226 0.12 ENST00000396188.2
transmembrane protease, serine 11A
chrY_+_20708557 0.11 ENST00000307393.2
ENST00000309834.4
ENST00000382856.2
heat shock transcription factor, Y-linked 1
chr9_-_95298254 0.11 ENST00000444490.2
extracellular matrix protein 2, female organ and adipocyte specific
chr3_+_46919235 0.11 ENST00000449590.1
parathyroid hormone 1 receptor
chr4_-_69111401 0.11 ENST00000332644.5
transmembrane protease, serine 11B
chr16_-_15474904 0.11 ENST00000534094.1
nuclear pore complex interacting protein family, member A5
chr1_-_160549235 0.10 ENST00000368054.3
ENST00000368048.3
ENST00000311224.4
ENST00000368051.3
ENST00000534968.1
CD84 molecule
chr9_+_44868935 0.10 ENST00000448436.2
RP11-160N1.10
chr20_-_7921090 0.09 ENST00000378789.3
hydroxyacid oxidase (glycolate oxidase) 1
chr6_-_32374900 0.09 ENST00000374995.3
ENST00000374993.1
ENST00000414363.1
ENST00000540315.1
ENST00000544175.1
ENST00000429232.2
ENST00000454136.3
ENST00000446536.2
butyrophilin-like 2 (MHC class II associated)
chr12_+_80750134 0.08 ENST00000546620.1
otogelin-like
chr4_+_3443614 0.08 ENST00000382774.3
ENST00000511533.1
HGF activator
chr6_-_161085291 0.07 ENST00000316300.5
lipoprotein, Lp(a)
chr11_+_22696314 0.06 ENST00000532398.1
ENST00000433790.1
growth arrest-specific 2
chr9_-_215744 0.06 ENST00000382387.2
chromosome 9 open reading frame 66
chr7_+_143806607 0.06 ENST00000408979.2
olfactory receptor, family 2, subfamily A, member 2
chr3_-_49066811 0.05 ENST00000442157.1
ENST00000326739.4
IMP (inosine 5'-monophosphate) dehydrogenase 2
chr12_-_10321754 0.05 ENST00000539518.1
oxidized low density lipoprotein (lectin-like) receptor 1
chr4_-_149365827 0.04 ENST00000344721.4
nuclear receptor subfamily 3, group C, member 2
chr1_+_63063152 0.04 ENST00000371129.3
angiopoietin-like 3
chr12_-_91546926 0.04 ENST00000550758.1
decorin
chr1_-_168464875 0.03 ENST00000422253.1
RP5-968D22.3
chr22_-_22337204 0.03 ENST00000430142.1
ENST00000357179.5
topoisomerase (DNA) III beta
chr1_-_247921982 0.03 ENST00000408896.2
olfactory receptor, family 1, subfamily C, member 1
chr9_-_95298314 0.03 ENST00000344604.5
ENST00000375540.1
extracellular matrix protein 2, female organ and adipocyte specific
chr12_+_59989918 0.02 ENST00000547379.1
ENST00000549465.1
solute carrier family 16 (monocarboxylate transporter), member 7
chr14_+_23709555 0.02 ENST00000430154.2
chromosome 14 open reading frame 164
chr14_-_104408645 0.02 ENST00000557640.1
retinal degeneration 3-like
chr5_+_118690466 0.02 ENST00000503646.1
tumor necrosis factor, alpha-induced protein 8
chr11_-_58378759 0.01 ENST00000601906.1
Uncharacterized protein
chr14_+_95027772 0.01 ENST00000555095.1
ENST00000298841.5
ENST00000554220.1
ENST00000553780.1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
chr4_-_100356551 0.00 ENST00000209665.4
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr12_+_59989791 0.00 ENST00000552432.1
solute carrier family 16 (monocarboxylate transporter), member 7
chr8_+_92114060 0.00 ENST00000518304.1
leucine rich repeat containing 69

Network of associatons between targets according to the STRING database.

First level regulatory network of ZFHX3

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.9 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.3 1.8 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.3 1.9 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.3 0.8 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
0.2 3.0 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.2 1.0 GO:0036509 trimming of terminal mannose on B branch(GO:0036509) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512)
0.2 1.9 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.1 0.5 GO:2000007 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.1 1.8 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.1 0.4 GO:0036367 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.1 0.4 GO:0051958 methotrexate transport(GO:0051958)
0.1 0.3 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.1 GO:0021530 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.0 1.8 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.1 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.0 0.2 GO:0061364 negative regulation of negative chemotaxis(GO:0050925) apoptotic process involved in luteolysis(GO:0061364)
0.0 0.1 GO:0009441 glycolate metabolic process(GO:0009441)
0.0 0.8 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0 0.1 GO:0032661 regulation of interleukin-18 production(GO:0032661)
0.0 0.2 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.0 0.2 GO:0048664 neuron fate determination(GO:0048664)
0.0 0.1 GO:0046373 arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373)
0.0 0.2 GO:0040031 snRNA modification(GO:0040031)
0.0 0.5 GO:0035640 exploration behavior(GO:0035640)
0.0 0.1 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.8 GO:0071062 rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.2 1.8 GO:0005579 membrane attack complex(GO:0005579)
0.2 3.0 GO:0005577 fibrinogen complex(GO:0005577)
0.1 1.9 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.5 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.3 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.1 GO:0044279 other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.0 1.0 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.8 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.2 GO:0045277 respiratory chain complex IV(GO:0045277)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.9 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.4 1.9 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.3 3.9 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.2 0.8 GO:0019770 IgG receptor activity(GO:0019770)
0.1 1.8 GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.1 0.3 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.1 0.4 GO:0015350 methotrexate transporter activity(GO:0015350)
0.1 1.0 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 1.8 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.1 GO:1904854 proteasome core complex binding(GO:1904854)
0.0 1.8 GO:0008009 chemokine activity(GO:0008009)
0.0 0.5 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.1 GO:0070052 collagen V binding(GO:0070052)
0.0 1.0 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.1 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.0 0.2 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.8 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.1 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.0 0.2 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.5 GO:0015278 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0 0.4 GO:0070492 phosphatidylinositol-5-phosphate binding(GO:0010314) oligosaccharide binding(GO:0070492)
0.0 0.1 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.1 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.0 0.8 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 1.1 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.1 GO:0003938 IMP dehydrogenase activity(GO:0003938)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.8 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 1.6 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.9 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 1.1 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.0 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 3.9 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 1.0 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 1.7 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 1.8 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling