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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for ZIC2_GLI1

Z-value: 0.57

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Transcription factors associated with ZIC2_GLI1

Gene Symbol Gene ID Gene Info
ZIC2
ENSG00000043355.6 Zic family member 2
GLI1
ENSG00000111087.5 GLI family zinc finger 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GLI1hg19_v2_chr12_+_57854274_578542740.751.4e-04Click!
ZIC2hg19_v2_chr13_+_100634004_1006340260.642.3e-03Click!

Activity profile of ZIC2_GLI1 motif

Sorted Z-values of ZIC2_GLI1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr22_-_46373004 1.75 ENST00000339464.4
WNT7B
wingless-type MMTV integration site family, member 7B
chr7_-_108097144 1.27 ENST00000418239.1
NRCAM
neuronal cell adhesion molecule
chr5_-_168727713 1.18 ENST00000404867.3
SLIT3
slit homolog 3 (Drosophila)
chr5_-_168727786 1.16 ENST00000332966.8
SLIT3
slit homolog 3 (Drosophila)
chr8_+_31497271 1.12 ENST00000520407.1
NRG1
neuregulin 1
chr7_-_108096822 1.05 ENST00000379028.3
ENST00000413765.2
ENST00000379022.4
NRCAM
neuronal cell adhesion molecule
chr16_+_19183671 0.98 ENST00000562711.2
SYT17
synaptotagmin XVII
chr16_+_57844549 0.97 ENST00000564282.1
CTD-2600O9.1
uncharacterized protein LOC388282
chr7_-_108096765 0.96 ENST00000379024.4
ENST00000351718.4
NRCAM
neuronal cell adhesion molecule
chr17_+_73089382 0.95 ENST00000538213.2
ENST00000584118.1
SLC16A5
solute carrier family 16 (monocarboxylate transporter), member 5
chr1_-_40105617 0.95 ENST00000372852.3
HEYL
hes-related family bHLH transcription factor with YRPW motif-like
chr20_+_43343476 0.88 ENST00000372868.2
WISP2
WNT1 inducible signaling pathway protein 2
chrX_+_12809463 0.86 ENST00000380663.3
ENST00000380668.5
ENST00000398491.2
ENST00000489404.1
PRPS2
phosphoribosyl pyrophosphate synthetase 2
chr17_+_40834580 0.85 ENST00000264638.4
CNTNAP1
contactin associated protein 1
chr20_+_43343886 0.82 ENST00000190983.4
WISP2
WNT1 inducible signaling pathway protein 2
chr8_-_17555164 0.80 ENST00000297488.6
MTUS1
microtubule associated tumor suppressor 1
chr3_+_10068095 0.79 ENST00000287647.3
ENST00000383807.1
ENST00000383806.1
ENST00000419585.1
FANCD2
Fanconi anemia, complementation group D2
chr9_-_98079154 0.78 ENST00000433829.1
FANCC
Fanconi anemia, complementation group C
chr20_+_43343517 0.76 ENST00000372865.4
WISP2
WNT1 inducible signaling pathway protein 2
chr8_-_117886563 0.75 ENST00000519837.1
ENST00000522699.1
RAD21
RAD21 homolog (S. pombe)
chr8_-_117886732 0.75 ENST00000517485.1
RAD21
RAD21 homolog (S. pombe)
chr16_+_88493879 0.74 ENST00000565624.1
ENST00000437464.1
ZNF469
zinc finger protein 469
chr12_+_57853918 0.73 ENST00000532291.1
ENST00000543426.1
ENST00000228682.2
ENST00000546141.1
GLI1
GLI family zinc finger 1
chr2_-_133427767 0.72 ENST00000397463.2
LYPD1
LY6/PLAUR domain containing 1
chrX_-_30327495 0.71 ENST00000453287.1
NR0B1
nuclear receptor subfamily 0, group B, member 1
chr8_-_117886612 0.69 ENST00000520992.1
RAD21
RAD21 homolog (S. pombe)
chr19_-_55881741 0.68 ENST00000264563.2
ENST00000590625.1
ENST00000585513.1
IL11
interleukin 11
chr6_-_26027480 0.68 ENST00000377364.3
HIST1H4B
histone cluster 1, H4b
chr1_+_164528866 0.68 ENST00000420696.2
PBX1
pre-B-cell leukemia homeobox 1
chr10_-_95360983 0.63 ENST00000371464.3
RBP4
retinol binding protein 4, plasma
chr15_-_26108355 0.59 ENST00000356865.6
ATP10A
ATPase, class V, type 10A
chr7_+_130131907 0.59 ENST00000223215.4
ENST00000437945.1
MEST
mesoderm specific transcript
chr11_-_46848393 0.59 ENST00000526496.1
CKAP5
cytoskeleton associated protein 5
chr2_+_97481974 0.57 ENST00000377060.3
ENST00000305510.3
CNNM3
cyclin M3
chr5_+_71403061 0.57 ENST00000512974.1
ENST00000296755.7
MAP1B
microtubule-associated protein 1B
chr8_-_117886955 0.57 ENST00000297338.2
RAD21
RAD21 homolog (S. pombe)
chr5_+_71403280 0.55 ENST00000511641.2
MAP1B
microtubule-associated protein 1B
chr17_+_43299156 0.54 ENST00000331495.3
FMNL1
formin-like 1
chr14_-_51561784 0.53 ENST00000360392.4
TRIM9
tripartite motif containing 9
chr2_-_28113965 0.52 ENST00000302188.3
RBKS
ribokinase
chr19_-_40919271 0.52 ENST00000291825.7
ENST00000324001.7
PRX
periaxin
chr5_+_102455968 0.50 ENST00000358359.3
PPIP5K2
diphosphoinositol pentakisphosphate kinase 2
chr11_+_76493294 0.50 ENST00000533752.1
TSKU
tsukushi, small leucine rich proteoglycan
chrX_-_107334790 0.49 ENST00000217958.3
PSMD10
proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
chr3_+_153839149 0.49 ENST00000465093.1
ENST00000465817.1
ARHGEF26
Rho guanine nucleotide exchange factor (GEF) 26
chr17_+_43239231 0.47 ENST00000591576.1
ENST00000591070.1
ENST00000592695.1
HEXIM2
hexamethylene bis-acetamide inducible 2
chr2_+_178977143 0.47 ENST00000286070.5
RBM45
RNA binding motif protein 45
chrX_-_107334750 0.45 ENST00000340200.5
ENST00000372296.1
ENST00000372295.1
ENST00000361815.5
PSMD10
proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
chr12_-_6798025 0.45 ENST00000542351.1
ENST00000538829.1
ZNF384
zinc finger protein 384
chrX_-_20237059 0.44 ENST00000457145.1
RPS6KA3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr3_+_110790867 0.44 ENST00000486596.1
ENST00000493615.1
PVRL3
poliovirus receptor-related 3
chr8_+_94752349 0.43 ENST00000391680.1
RBM12B-AS1
RBM12B antisense RNA 1
chr8_+_22225041 0.43 ENST00000289952.5
ENST00000524285.1
SLC39A14
solute carrier family 39 (zinc transporter), member 14
chr12_+_57854274 0.42 ENST00000528432.1
GLI1
GLI family zinc finger 1
chr2_+_25015968 0.42 ENST00000380834.2
ENST00000473706.1
CENPO
centromere protein O
chr10_-_98347063 0.41 ENST00000443638.1
TM9SF3
transmembrane 9 superfamily member 3
chr2_+_25016282 0.41 ENST00000260662.1
CENPO
centromere protein O
chr3_-_88108192 0.40 ENST00000309534.6
CGGBP1
CGG triplet repeat binding protein 1
chr1_+_42846443 0.40 ENST00000410070.2
ENST00000431473.3
RIMKLA
ribosomal modification protein rimK-like family member A
chr14_+_77228532 0.39 ENST00000167106.4
ENST00000554237.1
VASH1
vasohibin 1
chr3_+_88108381 0.39 ENST00000473136.1
RP11-159G9.5
Uncharacterized protein
chr11_+_45168182 0.38 ENST00000526442.1
PRDM11
PR domain containing 11
chr3_+_110790590 0.37 ENST00000485303.1
PVRL3
poliovirus receptor-related 3
chr16_+_86612112 0.37 ENST00000320241.3
FOXL1
forkhead box L1
chr7_+_114562616 0.37 ENST00000448022.1
MDFIC
MyoD family inhibitor domain containing
chr10_+_18948311 0.36 ENST00000377275.3
ARL5B
ADP-ribosylation factor-like 5B
chr16_-_1031259 0.36 ENST00000563837.1
ENST00000563863.1
ENST00000565069.1
ENST00000570014.1
RP11-161M6.2
LMF1
RP11-161M6.2
lipase maturation factor 1
chr22_-_50970566 0.35 ENST00000405135.1
ENST00000401779.1
ODF3B
outer dense fiber of sperm tails 3B
chr17_-_15496722 0.35 ENST00000472534.1
CDRT1
CMT1A duplicated region transcript 1
chr2_+_178257372 0.35 ENST00000264167.4
ENST00000409888.1
AGPS
alkylglycerone phosphate synthase
chr19_-_42758040 0.34 ENST00000593944.1
ERF
Ets2 repressor factor
chr15_-_65282274 0.34 ENST00000204566.2
SPG21
spastic paraplegia 21 (autosomal recessive, Mast syndrome)
chr15_-_65282232 0.33 ENST00000416889.2
SPG21
spastic paraplegia 21 (autosomal recessive, Mast syndrome)
chr15_-_78526942 0.32 ENST00000258873.4
ACSBG1
acyl-CoA synthetase bubblegum family member 1
chr9_-_86571628 0.32 ENST00000376344.3
C9orf64
chromosome 9 open reading frame 64
chr3_+_110790715 0.32 ENST00000319792.3
PVRL3
poliovirus receptor-related 3
chr22_-_50970506 0.32 ENST00000428989.2
ENST00000403326.1
ODF3B
outer dense fiber of sperm tails 3B
chr17_-_26989136 0.31 ENST00000247020.4
SDF2
stromal cell-derived factor 2
chr17_+_43238438 0.31 ENST00000593138.1
ENST00000586681.1
HEXIM2
hexamethylene bis-acetamide inducible 2
chr17_-_7137857 0.30 ENST00000005340.5
DVL2
dishevelled segment polarity protein 2
chr16_-_21452040 0.30 ENST00000521589.1
NPIPB3
nuclear pore complex interacting protein family, member B3
chr2_+_46769798 0.30 ENST00000238738.4
RHOQ
ras homolog family member Q
chr3_+_159481464 0.30 ENST00000467377.1
IQCJ-SCHIP1
IQCJ-SCHIP1 readthrough
chr4_-_38666430 0.30 ENST00000436901.1
AC021860.1
Uncharacterized protein
chr9_-_35103105 0.30 ENST00000452248.2
ENST00000356493.5
STOML2
stomatin (EPB72)-like 2
chr1_-_150208291 0.30 ENST00000533654.1
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chrX_+_152240819 0.29 ENST00000421798.3
ENST00000535416.1
PNMA6C
PNMA6A
paraneoplastic Ma antigen family member 6C
paraneoplastic Ma antigen family member 6A
chr17_-_40540377 0.29 ENST00000404395.3
ENST00000389272.3
ENST00000585517.1
ENST00000588065.1
STAT3
signal transducer and activator of transcription 3 (acute-phase response factor)
chr2_-_46769694 0.28 ENST00000522587.1
ATP6V1E2
ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E2
chr17_-_7137582 0.28 ENST00000575756.1
ENST00000575458.1
DVL2
dishevelled segment polarity protein 2
chrX_+_70364667 0.28 ENST00000536169.1
ENST00000395855.2
ENST00000374051.3
ENST00000358741.3
NLGN3
neuroligin 3
chr10_-_81203972 0.28 ENST00000372333.3
ZCCHC24
zinc finger, CCHC domain containing 24
chr14_+_64971438 0.28 ENST00000555321.1
ZBTB1
zinc finger and BTB domain containing 1
chr9_+_131218408 0.27 ENST00000351030.3
ENST00000604420.1
ENST00000535026.1
ENST00000448249.3
ENST00000393527.3
ODF2
outer dense fiber of sperm tails 2
chr14_+_105927191 0.27 ENST00000550551.1
MTA1
metastasis associated 1
chr15_-_65281775 0.27 ENST00000433215.2
ENST00000558415.1
ENST00000557795.1
SPG21
spastic paraplegia 21 (autosomal recessive, Mast syndrome)
chr7_+_114562909 0.27 ENST00000423503.1
ENST00000427207.1
MDFIC
MyoD family inhibitor domain containing
chr10_+_99344071 0.27 ENST00000370647.4
ENST00000370646.4
HOGA1
4-hydroxy-2-oxoglutarate aldolase 1
chr6_+_33172407 0.27 ENST00000374662.3
HSD17B8
hydroxysteroid (17-beta) dehydrogenase 8
chr9_-_98279241 0.27 ENST00000437951.1
ENST00000375274.2
ENST00000430669.2
ENST00000468211.2
PTCH1
patched 1
chr17_-_40540484 0.27 ENST00000588969.1
STAT3
signal transducer and activator of transcription 3 (acute-phase response factor)
chr9_-_33264557 0.26 ENST00000473781.1
ENST00000488499.1
BAG1
BCL2-associated athanogene
chr3_-_88108212 0.26 ENST00000482016.1
CGGBP1
CGG triplet repeat binding protein 1
chr2_+_28113583 0.26 ENST00000344773.2
ENST00000379624.1
ENST00000342045.2
ENST00000379632.2
ENST00000361704.2
BRE
brain and reproductive organ-expressed (TNFRSF1A modulator)
chr1_-_21606013 0.25 ENST00000357071.4
ECE1
endothelin converting enzyme 1
chr19_-_39330818 0.25 ENST00000594769.1
ENST00000602021.1
AC104534.3
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial
chr16_+_29818857 0.25 ENST00000567444.1
MAZ
MYC-associated zinc finger protein (purine-binding transcription factor)
chr17_-_27278445 0.24 ENST00000268756.3
ENST00000584685.1
PHF12
PHD finger protein 12
chr1_-_205782304 0.24 ENST00000367137.3
SLC41A1
solute carrier family 41 (magnesium transporter), member 1
chr9_+_131218336 0.24 ENST00000372814.3
ODF2
outer dense fiber of sperm tails 2
chr6_-_110500826 0.23 ENST00000265601.3
ENST00000447287.1
ENST00000444391.1
WASF1
WAS protein family, member 1
chr19_-_30199516 0.23 ENST00000591243.1
C19orf12
chromosome 19 open reading frame 12
chr7_-_100034060 0.23 ENST00000292330.2
PPP1R35
protein phosphatase 1, regulatory subunit 35
chr5_+_162864575 0.23 ENST00000512163.1
ENST00000393929.1
ENST00000340828.2
ENST00000511683.2
ENST00000510097.1
ENST00000511490.2
ENST00000510664.1
CCNG1
cyclin G1
chr17_+_43239191 0.23 ENST00000589230.1
HEXIM2
hexamethylene bis-acetamide inducible 2
chr17_+_73997796 0.22 ENST00000586261.1
CDK3
cyclin-dependent kinase 3
chr1_-_150208498 0.22 ENST00000314136.8
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr11_+_66059339 0.22 ENST00000327259.4
TMEM151A
transmembrane protein 151A
chr15_-_65282045 0.22 ENST00000558765.1
SPG21
spastic paraplegia 21 (autosomal recessive, Mast syndrome)
chr5_+_161494770 0.22 ENST00000414552.2
ENST00000361925.4
GABRG2
gamma-aminobutyric acid (GABA) A receptor, gamma 2
chr22_-_50970919 0.21 ENST00000329363.4
ENST00000437588.1
ODF3B
outer dense fiber of sperm tails 3B
chr11_-_34938039 0.21 ENST00000395787.3
APIP
APAF1 interacting protein
chr10_-_35104185 0.20 ENST00000374789.3
ENST00000374788.3
ENST00000346874.4
ENST00000374794.3
ENST00000350537.4
ENST00000374790.3
ENST00000374776.1
ENST00000374773.1
ENST00000545693.1
ENST00000545260.1
ENST00000340077.5
PARD3
par-3 family cell polarity regulator
chr17_+_76422409 0.20 ENST00000600087.1
AC061992.1
Uncharacterized protein
chr9_+_131218698 0.20 ENST00000434106.3
ENST00000546203.1
ENST00000446274.1
ENST00000421776.2
ENST00000432065.2
ODF2
outer dense fiber of sperm tails 2
chr11_-_57103327 0.19 ENST00000529002.1
ENST00000278412.2
SSRP1
structure specific recognition protein 1
chr2_+_26915584 0.19 ENST00000302909.3
KCNK3
potassium channel, subfamily K, member 3
chr20_-_30310797 0.19 ENST00000422920.1
BCL2L1
BCL2-like 1
chr9_-_136242909 0.18 ENST00000371991.3
ENST00000545297.1
SURF4
surfeit 4
chr3_+_47844399 0.18 ENST00000446256.2
ENST00000445061.1
DHX30
DEAH (Asp-Glu-Ala-His) box helicase 30
chr5_+_161495038 0.18 ENST00000393933.4
GABRG2
gamma-aminobutyric acid (GABA) A receptor, gamma 2
chr1_-_150208320 0.18 ENST00000534220.1
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr7_-_91875109 0.18 ENST00000412043.2
ENST00000430102.1
ENST00000425073.1
ENST00000394503.2
ENST00000454017.1
ENST00000440209.1
ENST00000413688.1
ENST00000452773.1
ENST00000433016.1
ENST00000394505.2
ENST00000422347.1
ENST00000458493.1
ENST00000425919.1
KRIT1
KRIT1, ankyrin repeat containing
chr1_-_150208412 0.18 ENST00000532744.1
ENST00000369114.5
ENST00000369115.2
ENST00000369116.4
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr12_-_122985494 0.18 ENST00000336229.4
ZCCHC8
zinc finger, CCHC domain containing 8
chr3_+_159481988 0.18 ENST00000472451.1
IQCJ-SCHIP1
IQCJ-SCHIP1 readthrough
chr8_-_71581377 0.18 ENST00000276590.4
ENST00000522447.1
LACTB2
lactamase, beta 2
chr8_-_22014339 0.18 ENST00000306317.2
LGI3
leucine-rich repeat LGI family, member 3
chr11_-_65321198 0.17 ENST00000530426.1
LTBP3
latent transforming growth factor beta binding protein 3
chr14_-_30396802 0.17 ENST00000415220.2
PRKD1
protein kinase D1
chr17_-_28618867 0.16 ENST00000394819.3
ENST00000577623.1
BLMH
bleomycin hydrolase
chr9_-_115818951 0.16 ENST00000553380.1
ENST00000374227.3
ZFP37
ZFP37 zinc finger protein
chr1_+_155293702 0.16 ENST00000368347.4
RUSC1
RUN and SH3 domain containing 1
chrX_-_51812268 0.16 ENST00000486010.1
ENST00000497164.1
ENST00000360134.6
ENST00000485287.1
ENST00000335504.5
ENST00000431659.1
MAGED4B
melanoma antigen family D, 4B
chr7_-_106301405 0.16 ENST00000523505.1
CCDC71L
coiled-coil domain containing 71-like
chr6_-_32821599 0.16 ENST00000354258.4
TAP1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr11_-_34937858 0.16 ENST00000278359.5
APIP
APAF1 interacting protein
chr4_+_95174445 0.16 ENST00000509418.1
SMARCAD1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr15_-_78526855 0.16 ENST00000541759.1
ENST00000558130.1
ACSBG1
acyl-CoA synthetase bubblegum family member 1
chr3_-_129513259 0.15 ENST00000329333.5
TMCC1
transmembrane and coiled-coil domain family 1
chr17_+_17380294 0.15 ENST00000268711.3
ENST00000580462.1
MED9
mediator complex subunit 9
chr14_+_92980111 0.15 ENST00000216487.7
ENST00000557762.1
RIN3
Ras and Rab interactor 3
chr15_-_101142362 0.15 ENST00000559577.1
ENST00000561308.1
ENST00000560133.1
ENST00000560941.1
ENST00000559736.1
ENST00000560272.1
LINS
lines homolog (Drosophila)
chr19_+_1383890 0.15 ENST00000539480.1
ENST00000313408.7
ENST00000414651.2
NDUFS7
NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase)
chr12_-_120966943 0.15 ENST00000552443.1
ENST00000547736.1
ENST00000445328.2
ENST00000547943.1
ENST00000288532.6
COQ5
coenzyme Q5 homolog, methyltransferase (S. cerevisiae)
chr19_+_45312347 0.15 ENST00000270233.6
ENST00000591520.1
BCAM
basal cell adhesion molecule (Lutheran blood group)
chr14_-_64971288 0.14 ENST00000394715.1
ZBTB25
zinc finger and BTB domain containing 25
chr3_-_52486841 0.14 ENST00000496590.1
TNNC1
troponin C type 1 (slow)
chr10_-_35379524 0.14 ENST00000374751.3
ENST00000374742.1
ENST00000602371.1
CUL2
cullin 2
chr11_+_933555 0.14 ENST00000534485.1
AP2A2
adaptor-related protein complex 2, alpha 2 subunit
chr16_+_29819096 0.14 ENST00000568411.1
ENST00000563012.1
ENST00000562557.1
MAZ
MYC-associated zinc finger protein (purine-binding transcription factor)
chr17_-_40835076 0.13 ENST00000591765.1
CCR10
chemokine (C-C motif) receptor 10
chr15_+_91478493 0.13 ENST00000418476.2
UNC45A
unc-45 homolog A (C. elegans)
chr19_+_36602104 0.13 ENST00000585332.1
ENST00000262637.4
OVOL3
ovo-like zinc finger 3
chr3_+_159481791 0.13 ENST00000460298.1
IQCJ-SCHIP1
IQCJ-SCHIP1 readthrough
chr12_-_117175819 0.13 ENST00000261318.3
ENST00000536380.1
C12orf49
chromosome 12 open reading frame 49
chr10_+_180405 0.12 ENST00000439456.1
ENST00000397962.3
ENST00000309776.4
ENST00000381602.4
ZMYND11
zinc finger, MYND-type containing 11
chr20_-_62493217 0.12 ENST00000601296.1
C20ORF135
C20ORF135
chr8_-_41522779 0.12 ENST00000522231.1
ENST00000314214.8
ENST00000348036.4
ENST00000457297.1
ENST00000522543.1
ANK1
ankyrin 1, erythrocytic
chr11_-_118789613 0.12 ENST00000532899.1
BCL9L
B-cell CLL/lymphoma 9-like
chrX_+_51928002 0.12 ENST00000375626.3
MAGED4
melanoma antigen family D, 4
chr16_+_86600857 0.12 ENST00000320354.4
FOXC2
forkhead box C2 (MFH-1, mesenchyme forkhead 1)
chr12_-_49333446 0.12 ENST00000537495.1
AC073610.5
Uncharacterized protein
chr1_+_44679370 0.12 ENST00000372290.4
DMAP1
DNA methyltransferase 1 associated protein 1
chr9_-_33264676 0.12 ENST00000472232.3
ENST00000379704.2
BAG1
BCL2-associated athanogene
chr9_-_115819039 0.11 ENST00000555206.1
ZFP37
ZFP37 zinc finger protein
chr7_+_116312411 0.11 ENST00000456159.1
ENST00000397752.3
ENST00000318493.6
MET
met proto-oncogene
chr12_-_129308041 0.11 ENST00000376740.4
SLC15A4
solute carrier family 15 (oligopeptide transporter), member 4
chr17_+_7608511 0.11 ENST00000226091.2
EFNB3
ephrin-B3
chr9_-_123476719 0.11 ENST00000373930.3
MEGF9
multiple EGF-like-domains 9
chr16_+_75256507 0.11 ENST00000495583.1
CTRB1
chymotrypsinogen B1
chr1_-_211752073 0.11 ENST00000367001.4
SLC30A1
solute carrier family 30 (zinc transporter), member 1
chr16_-_16317321 0.11 ENST00000205557.7
ENST00000575728.1
ABCC6
ATP-binding cassette, sub-family C (CFTR/MRP), member 6
chr7_-_105516923 0.10 ENST00000478915.1
ATXN7L1
ataxin 7-like 1
chr1_-_150208363 0.10 ENST00000436748.2
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr22_-_30783075 0.10 ENST00000215798.6
RNF215
ring finger protein 215
chr17_+_38497640 0.10 ENST00000394086.3
RARA
retinoic acid receptor, alpha
chr2_-_31360887 0.10 ENST00000420311.2
ENST00000356174.3
ENST00000324589.5
GALNT14
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)
chr17_-_40168698 0.10 ENST00000590774.1
DNAJC7
DnaJ (Hsp40) homolog, subfamily C, member 7
chr11_-_6640585 0.10 ENST00000533371.1
ENST00000528657.1
ENST00000436873.2
ENST00000299427.6
TPP1
tripeptidyl peptidase I
chr15_-_77363441 0.10 ENST00000346495.2
ENST00000424443.3
ENST00000561277.1
TSPAN3
tetraspanin 3
chr7_-_150777874 0.10 ENST00000540185.1
FASTK
Fas-activated serine/threonine kinase
chr17_-_42298201 0.10 ENST00000527034.1
UBTF
upstream binding transcription factor, RNA polymerase I
chr2_-_136288740 0.10 ENST00000264159.6
ENST00000536680.1
ZRANB3
zinc finger, RAN-binding domain containing 3
chr9_-_98079965 0.10 ENST00000289081.3
FANCC
Fanconi anemia, complementation group C
chr6_+_17281802 0.09 ENST00000509686.1
RBM24
RNA binding motif protein 24
chr9_-_139371533 0.09 ENST00000290037.6
ENST00000431893.2
ENST00000371706.3
SEC16A
SEC16 homolog A (S. cerevisiae)
chr11_-_64527425 0.09 ENST00000377432.3
PYGM
phosphorylase, glycogen, muscle
chr9_-_139372141 0.09 ENST00000313050.7
SEC16A
SEC16 homolog A (S. cerevisiae)
chr19_-_13068012 0.09 ENST00000316939.1
GADD45GIP1
growth arrest and DNA-damage-inducible, gamma interacting protein 1

Network of associatons between targets according to the STRING database.

First level regulatory network of ZIC2_GLI1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.7 GO:0060535 trachea cartilage morphogenesis(GO:0060535) inner medullary collecting duct development(GO:0072061)
0.4 2.3 GO:0061364 apoptotic process involved in luteolysis(GO:0061364)
0.3 1.0 GO:2000824 negative regulation of androgen receptor activity(GO:2000824)
0.3 1.2 GO:0060032 notochord regression(GO:0060032)
0.3 4.1 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.2 2.8 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.2 0.9 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.2 0.9 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.1 0.6 GO:0022007 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.1 0.5 GO:0035544 negative regulation of SNARE complex assembly(GO:0035544)
0.1 0.6 GO:0048807 female genitalia morphogenesis(GO:0048807)
0.1 0.6 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730) positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
0.1 1.1 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.1 0.5 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.1 0.1 GO:0003275 apoptotic process involved in outflow tract morphogenesis(GO:0003275) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256)
0.1 0.5 GO:0019303 D-ribose catabolic process(GO:0019303)
0.1 0.8 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.1 0.3 GO:1901860 positive regulation of mitochondrial DNA metabolic process(GO:1901860)
0.1 0.4 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.1 0.7 GO:1903659 regulation of complement-dependent cytotoxicity(GO:1903659)
0.1 0.3 GO:2000174 regulation of pro-T cell differentiation(GO:2000174) positive regulation of pro-T cell differentiation(GO:2000176)
0.1 0.3 GO:0008611 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.1 0.3 GO:0060024 rhythmic synaptic transmission(GO:0060024) positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.1 0.7 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.1 0.6 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.1 0.3 GO:0010157 response to chlorate(GO:0010157)
0.1 0.3 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.1 0.4 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
0.0 0.5 GO:0007498 mesoderm development(GO:0007498)
0.0 0.3 GO:1902499 positive regulation of protein autoubiquitination(GO:1902499)
0.0 0.3 GO:0019470 4-hydroxyproline catabolic process(GO:0019470)
0.0 1.1 GO:0061162 establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.0 0.3 GO:0010816 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.0 0.2 GO:0046967 cytosol to ER transport(GO:0046967)
0.0 0.7 GO:0030238 male sex determination(GO:0030238)
0.0 0.4 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.1 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
0.0 0.2 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.0 0.2 GO:1902460 transforming growth factor beta activation(GO:0036363) regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.0 0.9 GO:0097150 neuronal stem cell population maintenance(GO:0097150)
0.0 1.8 GO:0043486 histone exchange(GO:0043486)
0.0 0.4 GO:0033578 protein glycosylation in Golgi(GO:0033578)
0.0 0.5 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 1.0 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736)
0.0 0.1 GO:0036292 DNA rewinding(GO:0036292)
0.0 0.7 GO:0098926 acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.0 0.5 GO:0051014 actin filament severing(GO:0051014)
0.0 0.1 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
0.0 0.3 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.1 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.0 0.2 GO:0043418 homocysteine catabolic process(GO:0043418)
0.0 0.7 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.2 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 1.0 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 0.4 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.4 GO:0071420 cellular response to histamine(GO:0071420)
0.0 0.1 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.0 0.3 GO:0045023 G0 to G1 transition(GO:0045023)
0.0 0.7 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971)
0.0 0.1 GO:0016198 axon choice point recognition(GO:0016198)
0.0 0.2 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.6 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.0 0.1 GO:1903862 positive regulation of oxidative phosphorylation(GO:1903862)
0.0 0.0 GO:0035385 Roundabout signaling pathway(GO:0035385)
0.0 0.1 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.0 0.3 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.3 GO:0090005 negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.0 0.5 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.1 GO:0032252 secretory granule localization(GO:0032252)
0.0 0.1 GO:0045204 MAPK export from nucleus(GO:0045204)
0.0 0.2 GO:0051481 negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.0 0.1 GO:0006857 oligopeptide transport(GO:0006857)
0.0 0.2 GO:0034498 early endosome to Golgi transport(GO:0034498)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.8 GO:0000798 nuclear cohesin complex(GO:0000798)
0.2 0.9 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.1 3.3 GO:0043194 axon initial segment(GO:0043194)
0.1 0.9 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 0.7 GO:0042788 polysomal ribosome(GO:0042788)
0.1 0.5 GO:0001726 ruffle(GO:0001726)
0.1 0.8 GO:0033010 paranodal junction(GO:0033010)
0.0 0.9 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.7 GO:0001520 outer dense fiber(GO:0001520)
0.0 1.0 GO:0000812 Swr1 complex(GO:0000812)
0.0 0.3 GO:0031302 intrinsic component of endosome membrane(GO:0031302)
0.0 0.3 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.5 GO:0032059 bleb(GO:0032059)
0.0 1.3 GO:0030673 axolemma(GO:0030673)
0.0 0.1 GO:1990584 cardiac Troponin complex(GO:1990584)
0.0 0.2 GO:0042825 TAP complex(GO:0042825)
0.0 1.1 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 1.2 GO:0097546 ciliary base(GO:0097546)
0.0 0.7 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.1 GO:0030891 VCB complex(GO:0030891)
0.0 0.2 GO:0033269 internode region of axon(GO:0033269)
0.0 0.2 GO:0031209 SCAR complex(GO:0031209)
0.0 1.7 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.4 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.3 GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0035939 microsatellite binding(GO:0035939)
0.2 2.3 GO:0048495 Roundabout binding(GO:0048495)
0.2 0.7 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.1 3.3 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.1 0.4 GO:0072590 N-acetyl-L-aspartate-L-glutamate ligase activity(GO:0072590)
0.1 0.9 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.1 1.1 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 0.3 GO:0047025 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity(GO:0047025)
0.1 1.0 GO:0097322 7SK snRNA binding(GO:0097322)
0.1 0.3 GO:0032427 GBD domain binding(GO:0032427)
0.1 0.6 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.1 0.3 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 0.4 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.1 2.2 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 2.3 GO:0005109 frizzled binding(GO:0005109)
0.0 0.4 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 0.3 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.0 1.1 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.6 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.4 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.0 0.1 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
0.0 0.3 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.4 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.5 GO:0005522 profilin binding(GO:0005522)
0.0 0.6 GO:0016918 retinal binding(GO:0016918) retinol binding(GO:0019841)
0.0 0.3 GO:1901612 cardiolipin binding(GO:1901612)
0.0 0.1 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.0 0.8 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.2 GO:0046979 TAP2 binding(GO:0046979)
0.0 0.1 GO:0005055 laminin receptor activity(GO:0005055)
0.0 0.6 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.5 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.7 GO:0000217 DNA secondary structure binding(GO:0000217)
0.0 0.2 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.1 GO:0015333 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.0 0.3 GO:0005113 patched binding(GO:0005113)
0.0 1.2 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.7 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.1 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.0 0.1 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.0 0.1 GO:0031013 troponin I binding(GO:0031013)
0.0 0.4 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.1 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.0 0.1 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.0 0.1 GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)
0.0 1.0 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.1 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.0 GO:1904854 proteasome core complex binding(GO:1904854)
0.0 0.5 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.0 0.3 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.1 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.2 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.7 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.6 ST STAT3 PATHWAY STAT3 Pathway
0.0 0.7 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 1.7 PID BARD1 PATHWAY BARD1 signaling events
0.0 1.0 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.2 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 1.1 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.6 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 1.4 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.4 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 0.8 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.9 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 1.1 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.6 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 3.2 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.8 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 1.1 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 1.6 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.6 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.4 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.9 REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.0 0.4 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 1.5 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 1.4 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions