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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for ZIC3_ZIC4

Z-value: 1.00

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Transcription factors associated with ZIC3_ZIC4

Gene Symbol Gene ID Gene Info
ZIC3
ENSG00000156925.7 Zic family member 3
ZIC4
ENSG00000174963.13 Zic family member 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZIC3hg19_v2_chrX_+_136648643_1366487110.445.2e-02Click!
ZIC4hg19_v2_chr3_-_147124547_1471246470.029.5e-01Click!

Activity profile of ZIC3_ZIC4 motif

Sorted Z-values of ZIC3_ZIC4 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_43045439 5.20 ENST00000253407.3
C1QL1
complement component 1, q subcomponent-like 1
chr2_+_8822113 4.12 ENST00000396290.1
ENST00000331129.3
ID2
inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
chr14_+_31343747 4.01 ENST00000216361.4
ENST00000396618.3
ENST00000475087.1
COCH
cochlin
chr16_-_88717482 2.87 ENST00000261623.3
CYBA
cytochrome b-245, alpha polypeptide
chr17_+_38599693 2.70 ENST00000542955.1
ENST00000269593.4
IGFBP4
insulin-like growth factor binding protein 4
chr5_+_76506706 2.61 ENST00000340978.3
ENST00000346042.3
ENST00000264917.5
ENST00000342343.4
ENST00000333194.4
PDE8B
phosphodiesterase 8B
chr16_+_30996502 2.60 ENST00000353250.5
ENST00000262520.6
ENST00000297679.5
ENST00000562932.1
ENST00000574447.1
HSD3B7
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
chr21_+_37507210 2.48 ENST00000290354.5
CBR3
carbonyl reductase 3
chr12_+_49932886 2.44 ENST00000257981.6
KCNH3
potassium voltage-gated channel, subfamily H (eag-related), member 3
chr3_+_28283069 2.43 ENST00000466830.1
ENST00000423894.1
CMC1
C-x(9)-C motif containing 1
chr19_-_10024496 2.42 ENST00000593091.1
OLFM2
olfactomedin 2
chr20_-_62129163 2.34 ENST00000298049.7
EEF1A2
eukaryotic translation elongation factor 1 alpha 2
chr19_+_589893 2.32 ENST00000251287.2
HCN2
hyperpolarization activated cyclic nucleotide-gated potassium channel 2
chr5_+_75699149 2.29 ENST00000379730.3
IQGAP2
IQ motif containing GTPase activating protein 2
chr5_+_75699040 2.28 ENST00000274364.6
IQGAP2
IQ motif containing GTPase activating protein 2
chr12_+_132312931 2.27 ENST00000360564.1
ENST00000545671.1
ENST00000545790.1
MMP17
matrix metallopeptidase 17 (membrane-inserted)
chr11_-_65150103 2.22 ENST00000294187.6
ENST00000398802.1
ENST00000360662.3
ENST00000377152.2
ENST00000530936.1
SLC25A45
solute carrier family 25, member 45
chr7_+_150758304 2.18 ENST00000482950.1
ENST00000463414.1
ENST00000310317.5
SLC4A2
solute carrier family 4 (anion exchanger), member 2
chr2_+_37571717 2.15 ENST00000338415.3
ENST00000404976.1
QPCT
glutaminyl-peptide cyclotransferase
chr2_+_37571845 2.11 ENST00000537448.1
QPCT
glutaminyl-peptide cyclotransferase
chr1_-_212873267 2.02 ENST00000243440.1
BATF3
basic leucine zipper transcription factor, ATF-like 3
chr12_+_56075330 2.00 ENST00000394252.3
METTL7B
methyltransferase like 7B
chrX_-_30326445 1.96 ENST00000378963.1
NR0B1
nuclear receptor subfamily 0, group B, member 1
chr9_-_123639445 1.78 ENST00000312189.6
PHF19
PHD finger protein 19
chr3_-_129035120 1.77 ENST00000333762.4
H1FX
H1 histone family, member X
chr22_+_48972118 1.76 ENST00000358295.5
FAM19A5
family with sequence similarity 19 (chemokine (C-C motif)-like), member A5
chr11_+_69061594 1.75 ENST00000441339.2
ENST00000308946.3
ENST00000535407.1
MYEOV
myeloma overexpressed
chr20_+_34203794 1.75 ENST00000374273.3
SPAG4
sperm associated antigen 4
chr10_+_6779326 1.73 ENST00000417112.1
RP11-554I8.2
RP11-554I8.2
chr16_+_29466426 1.71 ENST00000567248.1
SLX1B
SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae)
chr3_+_71803201 1.71 ENST00000304411.2
GPR27
G protein-coupled receptor 27
chr19_-_8675559 1.70 ENST00000597188.1
ADAMTS10
ADAM metallopeptidase with thrombospondin type 1 motif, 10
chr16_+_2039946 1.70 ENST00000248121.2
ENST00000568896.1
SYNGR3
synaptogyrin 3
chr11_-_407103 1.67 ENST00000526395.1
SIGIRR
single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
chr17_+_38219063 1.67 ENST00000584985.1
ENST00000264637.4
ENST00000450525.2
THRA
thyroid hormone receptor, alpha
chr21_+_46825032 1.65 ENST00000400337.2
COL18A1
collagen, type XVIII, alpha 1
chrX_+_2746850 1.64 ENST00000381163.3
ENST00000338623.5
ENST00000542787.1
GYG2
glycogenin 2
chr9_-_130742792 1.64 ENST00000373095.1
FAM102A
family with sequence similarity 102, member A
chr16_+_4364762 1.59 ENST00000262366.3
GLIS2
GLIS family zinc finger 2
chr3_+_148847371 1.56 ENST00000296051.2
ENST00000460120.1
HPS3
Hermansky-Pudlak syndrome 3
chr13_+_35516390 1.56 ENST00000540320.1
ENST00000400445.3
ENST00000310336.4
NBEA
neurobeachin
chr18_+_2846972 1.54 ENST00000254528.3
EMILIN2
elastin microfibril interfacer 2
chr11_+_64781657 1.52 ENST00000533729.1
ARL2
ADP-ribosylation factor-like 2
chr17_-_73840415 1.49 ENST00000592386.1
ENST00000412096.2
ENST00000586147.1
UNC13D
unc-13 homolog D (C. elegans)
chr16_+_2570340 1.47 ENST00000568263.1
ENST00000293971.6
ENST00000302956.4
ENST00000413459.3
ENST00000566706.1
ENST00000569879.1
AMDHD2
amidohydrolase domain containing 2
chr15_+_80351910 1.46 ENST00000261749.6
ENST00000561060.1
ZFAND6
zinc finger, AN1-type domain 6
chr15_-_90294523 1.45 ENST00000300057.4
MESP1
mesoderm posterior 1 homolog (mouse)
chr1_-_16400086 1.43 ENST00000375662.4
FAM131C
family with sequence similarity 131, member C
chr8_-_27462822 1.41 ENST00000522098.1
CLU
clusterin
chr19_+_45251804 1.37 ENST00000164227.5
BCL3
B-cell CLL/lymphoma 3
chr11_+_64781575 1.37 ENST00000246747.4
ENST00000529384.1
ARL2
ADP-ribosylation factor-like 2
chr1_-_153521597 1.36 ENST00000368712.1
S100A3
S100 calcium binding protein A3
chr11_-_64014379 1.34 ENST00000309318.3
PPP1R14B
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr15_+_80351977 1.32 ENST00000559157.1
ENST00000561012.1
ENST00000564367.1
ENST00000558494.1
ZFAND6
zinc finger, AN1-type domain 6
chr11_-_67272794 1.31 ENST00000436757.2
ENST00000356404.3
PITPNM1
phosphatidylinositol transfer protein, membrane-associated 1
chrX_+_51927919 1.28 ENST00000416960.1
MAGED4
melanoma antigen family D, 4
chr2_-_242626127 1.27 ENST00000445261.1
DTYMK
deoxythymidylate kinase (thymidylate kinase)
chr20_+_3777078 1.26 ENST00000340833.4
CDC25B
cell division cycle 25B
chr20_+_3776936 1.20 ENST00000439880.2
CDC25B
cell division cycle 25B
chr16_+_29465822 1.20 ENST00000330181.5
ENST00000351581.4
SLX1B
SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae)
chr7_+_150758642 1.18 ENST00000488420.1
SLC4A2
solute carrier family 4 (anion exchanger), member 2
chr5_+_176873789 1.18 ENST00000323249.3
ENST00000502922.1
PRR7
proline rich 7 (synaptic)
chr19_-_12992244 1.17 ENST00000538460.1
DNASE2
deoxyribonuclease II, lysosomal
chr17_+_78194205 1.17 ENST00000573809.1
ENST00000361193.3
ENST00000574967.1
ENST00000576126.1
ENST00000411502.3
ENST00000546047.2
SLC26A11
solute carrier family 26 (anion exchanger), member 11
chr19_+_33685490 1.15 ENST00000253193.7
LRP3
low density lipoprotein receptor-related protein 3
chr19_+_34287751 1.14 ENST00000590771.1
ENST00000589786.1
ENST00000284006.6
ENST00000588881.1
KCTD15
potassium channel tetramerization domain containing 15
chr16_+_30205225 1.14 ENST00000345535.4
ENST00000251303.6
SLX1A
SLX1 structure-specific endonuclease subunit homolog A (S. cerevisiae)
chr22_+_19467261 1.13 ENST00000455750.1
ENST00000437685.2
ENST00000263201.1
ENST00000404724.3
CDC45
cell division cycle 45
chr17_-_38721711 1.13 ENST00000578085.1
ENST00000246657.2
CCR7
chemokine (C-C motif) receptor 7
chr3_-_9811595 1.13 ENST00000256460.3
CAMK1
calcium/calmodulin-dependent protein kinase I
chrX_-_19533379 1.12 ENST00000338883.4
MAP3K15
mitogen-activated protein kinase kinase kinase 15
chr2_+_20646824 1.12 ENST00000272233.4
RHOB
ras homolog family member B
chr9_+_140083099 1.11 ENST00000322310.5
SSNA1
Sjogren syndrome nuclear autoantigen 1
chr7_+_149571045 1.11 ENST00000479613.1
ENST00000606024.1
ENST00000464662.1
ENST00000425642.2
ATP6V0E2
ATPase, H+ transporting V0 subunit e2
chr12_-_7244469 1.10 ENST00000538050.1
ENST00000536053.2
C1R
complement component 1, r subcomponent
chr8_-_27850180 1.10 ENST00000380385.2
ENST00000301906.4
ENST00000354914.3
SCARA5
scavenger receptor class A, member 5 (putative)
chr10_-_134145321 1.09 ENST00000368625.4
ENST00000368619.3
ENST00000456004.1
ENST00000368620.2
STK32C
serine/threonine kinase 32C
chr15_+_80696666 1.08 ENST00000303329.4
ARNT2
aryl-hydrocarbon receptor nuclear translocator 2
chr1_-_153521714 1.07 ENST00000368713.3
S100A3
S100 calcium binding protein A3
chr17_-_73840774 1.07 ENST00000207549.4
UNC13D
unc-13 homolog D (C. elegans)
chr2_+_101436564 1.07 ENST00000335681.5
NPAS2
neuronal PAS domain protein 2
chr5_+_133707252 1.06 ENST00000506787.1
ENST00000507277.1
UBE2B
ubiquitin-conjugating enzyme E2B
chr2_-_175202151 1.06 ENST00000595354.1
AC018470.1
Uncharacterized protein FLJ46347
chr10_+_112257596 1.05 ENST00000369583.3
DUSP5
dual specificity phosphatase 5
chr16_+_30205754 1.05 ENST00000354723.6
ENST00000355544.5
SULT1A3
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
chr7_+_302918 1.05 ENST00000599994.1
AC187652.1
Protein LOC100996433
chr19_+_54695098 1.05 ENST00000396388.2
TSEN34
TSEN34 tRNA splicing endonuclease subunit
chr19_+_49617609 1.04 ENST00000221459.2
ENST00000486217.2
LIN7B
lin-7 homolog B (C. elegans)
chr8_+_90769967 1.03 ENST00000220751.4
RIPK2
receptor-interacting serine-threonine kinase 2
chr3_-_9811674 1.03 ENST00000411972.1
CAMK1
calcium/calmodulin-dependent protein kinase I
chr5_+_41925325 1.02 ENST00000296812.2
ENST00000281623.3
ENST00000509134.1
FBXO4
F-box protein 4
chr11_-_67275542 1.01 ENST00000531506.1
CDK2AP2
cyclin-dependent kinase 2 associated protein 2
chr16_-_74808710 1.01 ENST00000219368.3
ENST00000544337.1
FA2H
fatty acid 2-hydroxylase
chr1_+_52521928 1.00 ENST00000489308.2
BTF3L4
basic transcription factor 3-like 4
chr1_+_155293702 0.99 ENST00000368347.4
RUSC1
RUN and SH3 domain containing 1
chr17_-_79623597 0.99 ENST00000574024.1
ENST00000331056.5
PDE6G
phosphodiesterase 6G, cGMP-specific, rod, gamma
chr20_-_32274179 0.98 ENST00000343380.5
E2F1
E2F transcription factor 1
chr2_+_103236004 0.98 ENST00000233969.2
SLC9A2
solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
chr9_+_139738867 0.96 ENST00000436881.1
C9orf172
chromosome 9 open reading frame 172
chr5_+_176873446 0.94 ENST00000507881.1
PRR7
proline rich 7 (synaptic)
chr17_-_1083078 0.94 ENST00000574266.1
ENST00000302538.5
ABR
active BCR-related
chr12_+_121163538 0.94 ENST00000242592.4
ACADS
acyl-CoA dehydrogenase, C-2 to C-3 short chain
chr14_-_23822080 0.93 ENST00000397267.1
ENST00000354772.3
SLC22A17
solute carrier family 22, member 17
chr9_-_140082983 0.93 ENST00000323927.2
ANAPC2
anaphase promoting complex subunit 2
chr12_+_121163602 0.93 ENST00000411593.2
ACADS
acyl-CoA dehydrogenase, C-2 to C-3 short chain
chr1_+_38273818 0.92 ENST00000373042.4
C1orf122
chromosome 1 open reading frame 122
chr10_+_134258649 0.92 ENST00000392630.3
ENST00000321248.2
C10orf91
chromosome 10 open reading frame 91
chr2_-_107502456 0.91 ENST00000419159.2
ST6GAL2
ST6 beta-galactosamide alpha-2,6-sialyltranferase 2
chr17_-_7531121 0.91 ENST00000573566.1
ENST00000269298.5
SAT2
spermidine/spermine N1-acetyltransferase family member 2
chr12_-_99038732 0.91 ENST00000393042.3
ENST00000420861.1
ENST00000299157.4
ENST00000342502.2
IKBIP
IKBKB interacting protein
chr9_-_74383799 0.90 ENST00000377044.4
TMEM2
transmembrane protein 2
chr19_+_49617581 0.90 ENST00000391864.3
LIN7B
lin-7 homolog B (C. elegans)
chr2_-_233792837 0.88 ENST00000373552.4
ENST00000409079.1
NGEF
neuronal guanine nucleotide exchange factor
chr17_+_77030267 0.88 ENST00000581774.1
C1QTNF1
C1q and tumor necrosis factor related protein 1
chr17_+_48638371 0.87 ENST00000360761.4
ENST00000352832.5
ENST00000354983.4
CACNA1G
calcium channel, voltage-dependent, T type, alpha 1G subunit
chr5_+_139055021 0.86 ENST00000502716.1
ENST00000503511.1
CXXC5
CXXC finger protein 5
chr19_-_12992274 0.86 ENST00000592506.1
ENST00000222219.3
DNASE2
deoxyribonuclease II, lysosomal
chr16_+_2198604 0.85 ENST00000210187.6
RAB26
RAB26, member RAS oncogene family
chr10_+_35416223 0.85 ENST00000489321.1
ENST00000427847.2
ENST00000345491.3
ENST00000395895.2
ENST00000374728.3
ENST00000487132.1
CREM
cAMP responsive element modulator
chr9_-_123639304 0.84 ENST00000436309.1
PHF19
PHD finger protein 19
chr5_+_139055055 0.84 ENST00000511457.1
CXXC5
CXXC finger protein 5
chr19_-_50063907 0.84 ENST00000598296.1
NOSIP
nitric oxide synthase interacting protein
chr16_+_56691606 0.83 ENST00000334350.6
MT1F
metallothionein 1F
chr20_-_4982132 0.82 ENST00000338244.1
ENST00000424750.2
SLC23A2
solute carrier family 23 (ascorbic acid transporter), member 2
chr5_+_139027877 0.82 ENST00000302517.3
CXXC5
CXXC finger protein 5
chr5_-_132948216 0.82 ENST00000265342.7
FSTL4
follistatin-like 4
chr6_-_85473156 0.81 ENST00000606784.1
ENST00000606325.1
TBX18
T-box 18
chr2_+_128180842 0.81 ENST00000402125.2
PROC
protein C (inactivator of coagulation factors Va and VIIIa)
chr8_+_90770008 0.80 ENST00000540020.1
RIPK2
receptor-interacting serine-threonine kinase 2
chr18_+_43684298 0.80 ENST00000282058.6
HAUS1
HAUS augmin-like complex, subunit 1
chr5_-_179499108 0.80 ENST00000521389.1
RNF130
ring finger protein 130
chr10_+_28966271 0.80 ENST00000375533.3
BAMBI
BMP and activin membrane-bound inhibitor
chr8_+_90914073 0.78 ENST00000297438.2
OSGIN2
oxidative stress induced growth inhibitor family member 2
chr19_-_40791160 0.78 ENST00000358335.5
AKT2
v-akt murine thymoma viral oncogene homolog 2
chr17_+_59477233 0.77 ENST00000240328.3
TBX2
T-box 2
chr1_-_11751529 0.77 ENST00000376672.1
MAD2L2
MAD2 mitotic arrest deficient-like 2 (yeast)
chr2_-_10220538 0.76 ENST00000381813.4
CYS1
cystin 1
chr19_-_49122384 0.76 ENST00000550973.1
ENST00000550645.1
ENST00000549273.1
ENST00000552588.1
RPL18
ribosomal protein L18
chr14_+_100848311 0.75 ENST00000542471.2
WDR25
WD repeat domain 25
chr17_+_27894180 0.74 ENST00000583940.1
TP53I13
tumor protein p53 inducible protein 13
chr17_-_40428359 0.73 ENST00000293328.3
STAT5B
signal transducer and activator of transcription 5B
chr1_+_38273988 0.73 ENST00000446260.2
C1orf122
chromosome 1 open reading frame 122
chr9_-_34662651 0.72 ENST00000259631.4
CCL27
chemokine (C-C motif) ligand 27
chr7_+_74379083 0.72 ENST00000361825.7
GATSL1
GATS protein-like 1
chr20_-_62680984 0.72 ENST00000340356.7
SOX18
SRY (sex determining region Y)-box 18
chr17_-_74733404 0.71 ENST00000508921.3
ENST00000583836.1
ENST00000358156.6
ENST00000392485.2
ENST00000359995.5
SRSF2
serine/arginine-rich splicing factor 2
chrX_+_2746818 0.71 ENST00000398806.3
GYG2
glycogenin 2
chr17_-_27893990 0.71 ENST00000307201.4
ABHD15
abhydrolase domain containing 15
chr3_+_100053542 0.71 ENST00000394140.4
NIT2
nitrilase family, member 2
chr19_+_59055814 0.70 ENST00000594806.1
ENST00000253024.5
ENST00000341753.6
TRIM28
tripartite motif containing 28
chr18_+_43684310 0.70 ENST00000592471.1
ENST00000585518.1
HAUS1
HAUS augmin-like complex, subunit 1
chr19_-_49314269 0.69 ENST00000545387.2
ENST00000316273.6
ENST00000402551.1
ENST00000598162.1
ENST00000599246.1
BCAT2
branched chain amino-acid transaminase 2, mitochondrial
chr16_-_2059797 0.69 ENST00000563630.1
ZNF598
zinc finger protein 598
chr19_-_40791302 0.68 ENST00000392038.2
ENST00000578123.1
AKT2
v-akt murine thymoma viral oncogene homolog 2
chr22_-_20368028 0.68 ENST00000404912.1
GGTLC3
gamma-glutamyltransferase light chain 3
chr17_+_78194261 0.67 ENST00000572725.1
SLC26A11
solute carrier family 26 (anion exchanger), member 11
chr19_+_47523058 0.67 ENST00000602212.1
ENST00000602189.1
NPAS1
neuronal PAS domain protein 1
chrX_-_34675391 0.67 ENST00000275954.3
TMEM47
transmembrane protein 47
chr7_+_155250824 0.67 ENST00000297375.4
EN2
engrailed homeobox 2
chr19_+_984313 0.66 ENST00000251289.5
ENST00000587001.2
ENST00000607440.1
WDR18
WD repeat domain 18
chr7_-_752577 0.66 ENST00000544935.1
ENST00000430040.1
ENST00000456696.2
ENST00000406797.1
PRKAR1B
protein kinase, cAMP-dependent, regulatory, type I, beta
chr3_+_12330560 0.66 ENST00000397026.2
PPARG
peroxisome proliferator-activated receptor gamma
chr9_-_139581848 0.65 ENST00000538402.1
ENST00000371694.3
AGPAT2
1-acylglycerol-3-phosphate O-acyltransferase 2
chr1_-_235814048 0.65 ENST00000450593.1
ENST00000366598.4
GNG4
guanine nucleotide binding protein (G protein), gamma 4
chr17_-_15903002 0.65 ENST00000399277.1
ZSWIM7
zinc finger, SWIM-type containing 7
chr16_-_29466285 0.65 ENST00000330978.3
BOLA2
bolA family member 2
chr2_-_42721110 0.64 ENST00000394973.4
ENST00000306078.1
KCNG3
potassium voltage-gated channel, subfamily G, member 3
chr6_-_85473073 0.64 ENST00000606621.1
TBX18
T-box 18
chr9_-_139581875 0.64 ENST00000371696.2
AGPAT2
1-acylglycerol-3-phosphate O-acyltransferase 2
chr1_-_52521831 0.64 ENST00000371626.4
TXNDC12
thioredoxin domain containing 12 (endoplasmic reticulum)
chr7_-_135412925 0.64 ENST00000354042.4
SLC13A4
solute carrier family 13 (sodium/sulfate symporter), member 4
chr22_+_19466980 0.64 ENST00000407835.1
ENST00000438587.1
CDC45
cell division cycle 45
chr3_+_100053625 0.63 ENST00000497785.1
NIT2
nitrilase family, member 2
chr5_-_179499086 0.63 ENST00000261947.4
RNF130
ring finger protein 130
chr2_+_219187871 0.63 ENST00000258362.3
PNKD
paroxysmal nonkinesigenic dyskinesia
chr3_+_184097836 0.63 ENST00000204604.1
ENST00000310236.3
CHRD
chordin
chr11_-_17555421 0.63 ENST00000526181.1
USH1C
Usher syndrome 1C (autosomal recessive, severe)
chr17_-_78194147 0.62 ENST00000534910.1
ENST00000326317.6
SGSH
N-sulfoglucosamine sulfohydrolase
chr8_-_101157680 0.62 ENST00000428847.2
FBXO43
F-box protein 43
chr3_+_143690640 0.62 ENST00000315691.3
C3orf58
chromosome 3 open reading frame 58
chr11_-_66139617 0.62 ENST00000544554.1
ENST00000546034.1
SLC29A2
solute carrier family 29 (equilibrative nucleoside transporter), member 2
chr19_+_5823813 0.61 ENST00000303212.2
NRTN
neurturin
chr19_-_40790729 0.61 ENST00000423127.1
ENST00000583859.1
ENST00000456441.1
ENST00000452077.1
AKT2
v-akt murine thymoma viral oncogene homolog 2
chr16_-_8962200 0.61 ENST00000562843.1
ENST00000561530.1
ENST00000396593.2
CARHSP1
calcium regulated heat stable protein 1, 24kDa
chr5_-_76383133 0.61 ENST00000255198.2
ZBED3
zinc finger, BED-type containing 3
chr19_-_40791211 0.61 ENST00000579047.1
AKT2
v-akt murine thymoma viral oncogene homolog 2
chr2_-_98280383 0.61 ENST00000289228.5
ACTR1B
ARP1 actin-related protein 1 homolog B, centractin beta (yeast)
chr9_+_100174344 0.59 ENST00000422139.2
TDRD7
tudor domain containing 7
chr9_-_123639600 0.59 ENST00000373896.3
PHF19
PHD finger protein 19
chr19_+_17858509 0.59 ENST00000594202.1
ENST00000252771.7
ENST00000389133.4
FCHO1
FCH domain only 1
chr17_-_73266616 0.59 ENST00000579194.1
ENST00000581777.1
MIF4GD
MIF4G domain containing
chr1_-_40105617 0.59 ENST00000372852.3
HEYL
hes-related family bHLH transcription factor with YRPW motif-like
chr16_-_69364467 0.58 ENST00000288022.1
PDF
peptide deformylase (mitochondrial)
chr11_-_71159458 0.58 ENST00000355527.3
DHCR7
7-dehydrocholesterol reductase
chr3_+_183948161 0.58 ENST00000426955.2
VWA5B2
von Willebrand factor A domain containing 5B2
chrX_-_131352152 0.58 ENST00000342983.2
RAP2C
RAP2C, member of RAS oncogene family
chr16_-_30205627 0.58 ENST00000305321.4
BOLA2B
bolA family member 2B
chr2_+_74781828 0.57 ENST00000340004.6
DOK1
docking protein 1, 62kDa (downstream of tyrosine kinase 1)
chrX_-_49056635 0.57 ENST00000472598.1
ENST00000538567.1
ENST00000479808.1
ENST00000263233.4
SYP
synaptophysin
chrX_+_102631248 0.57 ENST00000361298.4
ENST00000372645.3
ENST00000372635.1
NGFRAP1
nerve growth factor receptor (TNFRSF16) associated protein 1

Network of associatons between targets according to the STRING database.

First level regulatory network of ZIC3_ZIC4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.2 GO:0099558 maintenance of synapse structure(GO:0099558)
1.4 4.3 GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
0.8 4.1 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.8 3.1 GO:0002432 granuloma formation(GO:0002432)
0.6 1.8 GO:0036388 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.6 2.9 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.6 1.7 GO:1900738 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.6 1.7 GO:0045925 positive regulation of female receptivity(GO:0045925)
0.5 1.6 GO:0100012 regulation of heart induction(GO:0090381) regulation of heart induction by canonical Wnt signaling pathway(GO:0100012)
0.5 2.5 GO:1901662 phylloquinone metabolic process(GO:0042374) phylloquinone catabolic process(GO:0042376) quinone catabolic process(GO:1901662)
0.5 1.5 GO:0060829 regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060827) negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829)
0.5 1.4 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.4 1.3 GO:0021919 BMP signaling pathway involved in spinal cord dorsal/ventral patterning(GO:0021919)
0.4 3.0 GO:0097473 cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.4 1.1 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.4 1.8 GO:0033091 positive regulation of immature T cell proliferation(GO:0033091)
0.4 1.1 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.3 1.0 GO:0071930 negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.3 1.3 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.3 0.9 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.3 2.2 GO:0000066 mitochondrial ornithine transport(GO:0000066)
0.3 1.7 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.3 0.8 GO:0070904 L-ascorbic acid transport(GO:0015882) molecular hydrogen transport(GO:0015993) transepithelial L-ascorbic acid transport(GO:0070904)
0.3 0.8 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.3 2.4 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.3 1.1 GO:0006550 isoleucine catabolic process(GO:0006550)
0.3 1.1 GO:0006669 sphinganine-1-phosphate biosynthetic process(GO:0006669)
0.3 0.5 GO:1902512 positive regulation of apoptotic DNA fragmentation(GO:1902512)
0.3 1.0 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.3 0.8 GO:1901207 regulation of heart looping(GO:1901207)
0.2 3.2 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.2 1.7 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.2 1.9 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.2 0.9 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.2 1.6 GO:0060994 regulation of transcription from RNA polymerase II promoter involved in kidney development(GO:0060994)
0.2 1.1 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.2 2.6 GO:0035754 B cell chemotaxis(GO:0035754)
0.2 1.9 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.2 0.6 GO:0051596 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.2 0.8 GO:0044537 regulation of circulating fibrinogen levels(GO:0044537)
0.2 2.4 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.2 0.6 GO:2000824 negative regulation of androgen receptor activity(GO:2000824)
0.2 1.4 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.2 2.3 GO:0071321 cellular response to cGMP(GO:0071321)
0.2 0.6 GO:0042450 arginine biosynthetic process via ornithine(GO:0042450)
0.2 0.6 GO:0016260 selenocysteine biosynthetic process(GO:0016260)
0.2 2.3 GO:0042756 drinking behavior(GO:0042756)
0.2 0.9 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.2 2.5 GO:0007144 female meiosis I(GO:0007144)
0.2 4.6 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.2 1.7 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.2 0.7 GO:2000230 negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.2 1.1 GO:1904431 positive regulation of t-circle formation(GO:1904431)
0.2 1.3 GO:2000035 regulation of stem cell division(GO:2000035)
0.2 0.8 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.2 0.6 GO:1904106 protein localization to microvillus(GO:1904106)
0.2 0.9 GO:1902499 positive regulation of protein autoubiquitination(GO:1902499)
0.1 0.4 GO:0021722 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.1 0.1 GO:0060823 canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060823)
0.1 0.7 GO:0006549 isoleucine metabolic process(GO:0006549)
0.1 2.4 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.1 0.7 GO:1901536 negative regulation of DNA demethylation(GO:1901536)
0.1 0.6 GO:0071348 cellular response to interleukin-11(GO:0071348)
0.1 0.8 GO:0033490 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.1 3.1 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.1 2.4 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.1 1.1 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.1 0.8 GO:0006235 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
0.1 0.6 GO:0044571 [2Fe-2S] cluster assembly(GO:0044571)
0.1 2.2 GO:0030238 male sex determination(GO:0030238)
0.1 0.6 GO:0018364 peptidyl-glutamine methylation(GO:0018364)
0.1 1.3 GO:0006528 asparagine metabolic process(GO:0006528)
0.1 0.2 GO:0009957 epidermal cell fate specification(GO:0009957)
0.1 0.6 GO:0043686 co-translational protein modification(GO:0043686)
0.1 2.9 GO:0007021 tubulin complex assembly(GO:0007021)
0.1 0.9 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.1 1.0 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.1 0.4 GO:0072302 negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302)
0.1 0.9 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.1 0.8 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.1 0.9 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.1 0.6 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.1 0.8 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
0.1 0.4 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.1 0.7 GO:0048865 stem cell fate commitment(GO:0048865)
0.1 2.5 GO:0008272 sulfate transport(GO:0008272)
0.1 0.4 GO:0006272 leading strand elongation(GO:0006272)
0.1 0.7 GO:0010587 miRNA catabolic process(GO:0010587)
0.1 0.3 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.1 0.9 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.1 0.4 GO:0006015 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.1 3.1 GO:0072662 protein targeting to peroxisome(GO:0006625) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.1 0.5 GO:0021539 subthalamus development(GO:0021539)
0.1 0.1 GO:0002514 B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
0.1 1.3 GO:0050713 negative regulation of interleukin-1 beta secretion(GO:0050713)
0.1 0.1 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
0.1 0.3 GO:0035927 RNA import into mitochondrion(GO:0035927)
0.1 0.8 GO:0051001 negative regulation of nitric-oxide synthase activity(GO:0051001)
0.1 0.2 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.1 0.3 GO:0010157 response to chlorate(GO:0010157)
0.1 0.2 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.1 1.8 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.1 0.2 GO:0040040 thermosensory behavior(GO:0040040)
0.1 0.4 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.1 0.5 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 0.2 GO:0002572 pro-T cell differentiation(GO:0002572) regulation of pro-T cell differentiation(GO:2000174) positive regulation of pro-T cell differentiation(GO:2000176)
0.1 1.7 GO:0043488 regulation of mRNA stability(GO:0043488)
0.1 0.7 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.1 0.3 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.1 0.2 GO:0060723 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.1 2.0 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.1 0.4 GO:0098532 spermatogenesis, exchange of chromosomal proteins(GO:0035093) histone H3-K27 trimethylation(GO:0098532)
0.1 3.5 GO:0015701 bicarbonate transport(GO:0015701)
0.1 0.5 GO:0015793 glycerol transport(GO:0015793)
0.1 1.1 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 0.4 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.1 0.3 GO:0038169 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.1 0.3 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.1 0.2 GO:1990697 protein depalmitoleylation(GO:1990697)
0.1 1.0 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 1.1 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.4 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 3.0 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.0 0.1 GO:0000960 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.0 0.6 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.0 0.4 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.0 0.4 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.0 0.0 GO:0030908 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.0 0.7 GO:1990403 embryonic brain development(GO:1990403)
0.0 0.6 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
0.0 0.9 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.0 1.3 GO:0071294 cellular response to zinc ion(GO:0071294)
0.0 0.4 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.5 GO:1904322 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.0 2.1 GO:0005980 glycogen catabolic process(GO:0005980)
0.0 0.5 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 1.5 GO:0070207 protein homotrimerization(GO:0070207)
0.0 0.2 GO:1902075 cellular response to salt(GO:1902075)
0.0 0.2 GO:1902659 regulation of glucose mediated signaling pathway(GO:1902659)
0.0 0.6 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 0.2 GO:1901857 positive regulation of cellular respiration(GO:1901857)
0.0 0.7 GO:0033197 response to vitamin E(GO:0033197)
0.0 0.5 GO:0060312 regulation of blood vessel remodeling(GO:0060312)
0.0 0.3 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.1 GO:0021912 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912)
0.0 0.8 GO:0060746 maternal behavior(GO:0042711) parental behavior(GO:0060746)
0.0 1.1 GO:0061154 endothelial tube morphogenesis(GO:0061154)
0.0 0.2 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
0.0 0.1 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.0 0.8 GO:0035413 positive regulation of catenin import into nucleus(GO:0035413)
0.0 0.1 GO:0003274 endocardial cushion fusion(GO:0003274)
0.0 0.2 GO:0038183 bile acid signaling pathway(GO:0038183)
0.0 0.4 GO:0031125 rRNA 3'-end processing(GO:0031125)
0.0 0.1 GO:0002384 hepatic immune response(GO:0002384)
0.0 0.9 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.3 GO:0046813 receptor-mediated virion attachment to host cell(GO:0046813)
0.0 0.5 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 1.1 GO:0007035 vacuolar acidification(GO:0007035)
0.0 0.2 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.0 0.7 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 0.2 GO:2000672 regulation of motor neuron apoptotic process(GO:2000671) negative regulation of motor neuron apoptotic process(GO:2000672)
0.0 0.4 GO:0036123 histone H3-K9 dimethylation(GO:0036123)
0.0 0.1 GO:0051586 positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
0.0 0.2 GO:0015692 lead ion transport(GO:0015692)
0.0 0.6 GO:0051775 response to redox state(GO:0051775)
0.0 0.1 GO:0060059 embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.0 0.4 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0 0.6 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.6 GO:0003299 muscle hypertrophy in response to stress(GO:0003299) cardiac muscle adaptation(GO:0014887) cardiac muscle hypertrophy in response to stress(GO:0014898)
0.0 1.3 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.0 0.4 GO:0002087 regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.0 0.8 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.6 GO:1901642 nucleoside transmembrane transport(GO:1901642)
0.0 2.3 GO:0007602 phototransduction(GO:0007602)
0.0 0.5 GO:0070129 regulation of mitochondrial translation(GO:0070129)
0.0 0.7 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.0 0.1 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143)
0.0 0.3 GO:0060174 limb bud formation(GO:0060174)
0.0 0.1 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.0 0.4 GO:0035330 regulation of hippo signaling(GO:0035330)
0.0 0.6 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.1 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.0 0.5 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.0 0.3 GO:0034465 response to carbon monoxide(GO:0034465) smooth muscle contraction involved in micturition(GO:0060083)
0.0 0.3 GO:0061042 vascular wound healing(GO:0061042)
0.0 0.5 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.2 GO:2000582 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.4 GO:0010919 regulation of inositol phosphate biosynthetic process(GO:0010919) positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.0 0.1 GO:0042256 mature ribosome assembly(GO:0042256)
0.0 0.4 GO:0035090 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0 0.4 GO:0051601 exocyst localization(GO:0051601)
0.0 1.9 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.0 0.3 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.2 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.0 0.5 GO:0097237 cellular response to toxic substance(GO:0097237)
0.0 0.1 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 0.2 GO:1904251 regulation of bile acid metabolic process(GO:1904251)
0.0 0.5 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.2 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.0 GO:1900020 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.0 0.9 GO:0010165 response to X-ray(GO:0010165)
0.0 0.1 GO:0001773 myeloid dendritic cell activation(GO:0001773)
0.0 0.1 GO:0022401 desensitization of G-protein coupled receptor protein signaling pathway(GO:0002029) negative adaptation of signaling pathway(GO:0022401) adaptation of signaling pathway(GO:0023058)
0.0 0.5 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 1.7 GO:0032411 positive regulation of transporter activity(GO:0032411)
0.0 0.2 GO:0010990 regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.7 GO:0009409 response to cold(GO:0009409)
0.0 0.2 GO:1903874 ferrous iron transport(GO:0015684) ferrous iron transmembrane transport(GO:1903874)
0.0 1.1 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 1.0 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.0 0.3 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.4 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.0 0.2 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.0 0.2 GO:0090004 positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.0 0.7 GO:0035272 exocrine system development(GO:0035272)
0.0 0.1 GO:0031087 nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 5.2 GO:0044301 climbing fiber(GO:0044301)
0.8 2.3 GO:0098855 HCN channel complex(GO:0098855)
0.6 1.8 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.4 1.6 GO:0031084 BLOC-2 complex(GO:0031084)
0.3 1.4 GO:0097196 Shu complex(GO:0097196)
0.3 1.4 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.3 1.0 GO:0035189 Rb-E2F complex(GO:0035189)
0.2 1.0 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.2 2.3 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.2 3.1 GO:0033093 Weibel-Palade body(GO:0033093)
0.2 2.0 GO:0042788 polysomal ribosome(GO:0042788)
0.1 0.6 GO:0005600 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.1 2.9 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 0.8 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.1 1.9 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.1 0.4 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.1 0.4 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.1 1.5 GO:0070652 HAUS complex(GO:0070652)
0.1 1.0 GO:0033503 HULC complex(GO:0033503)
0.1 0.7 GO:0035061 interchromatin granule(GO:0035061)
0.1 1.8 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.1 0.4 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.1 0.3 GO:0097598 sperm cytoplasmic droplet(GO:0097598)
0.1 1.4 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.1 0.4 GO:1990031 pinceau fiber(GO:1990031)
0.1 1.3 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.1 1.1 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.1 0.3 GO:0031523 Myb complex(GO:0031523)
0.1 1.7 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.1 0.8 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.1 5.7 GO:0035580 specific granule lumen(GO:0035580)
0.1 0.6 GO:0042382 paraspeckles(GO:0042382)
0.1 0.4 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.1 0.9 GO:0071439 clathrin complex(GO:0071439)
0.1 0.3 GO:0034753 nuclear aryl hydrocarbon receptor complex(GO:0034753)
0.1 3.9 GO:0031941 filamentous actin(GO:0031941)
0.0 2.4 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.8 GO:0033391 chromatoid body(GO:0033391)
0.0 1.1 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.3 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.2 GO:0019031 viral envelope(GO:0019031) viral membrane(GO:0036338)
0.0 0.4 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.0 0.8 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
0.0 0.5 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 4.6 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.6 GO:0005869 dynactin complex(GO:0005869)
0.0 0.3 GO:0016592 mediator complex(GO:0016592)
0.0 0.2 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.0 4.3 GO:0005581 collagen trimer(GO:0005581)
0.0 1.0 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.2 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.0 0.2 GO:0070826 paraferritin complex(GO:0070826)
0.0 0.3 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 1.8 GO:0000786 nucleosome(GO:0000786)
0.0 0.9 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 1.0 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.2 GO:0044305 calyx of Held(GO:0044305)
0.0 0.6 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 3.4 GO:0043202 lysosomal lumen(GO:0043202)
0.0 0.5 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.1 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.1 GO:0070703 inner mucus layer(GO:0070702) outer mucus layer(GO:0070703)
0.0 0.4 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 2.2 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.9 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 1.3 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.5 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 1.7 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.6 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 0.8 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.2 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.1 GO:0031417 NatC complex(GO:0031417)
0.0 0.6 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.5 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 1.6 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.1 GO:0089701 U2AF(GO:0089701)
0.0 0.2 GO:0044327 dendritic spine head(GO:0044327)
0.0 2.2 GO:0032587 ruffle membrane(GO:0032587)
0.0 1.4 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.1 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 1.0 GO:0045095 keratin filament(GO:0045095)
0.0 0.6 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 1.3 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 2.3 GO:0031225 anchored component of membrane(GO:0031225)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.3 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.8 2.5 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.7 2.0 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.6 2.8 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
0.5 2.3 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.5 1.4 GO:0016250 N-sulfoglucosamine sulfohydrolase activity(GO:0016250) hydrolase activity, acting on acid sulfur-nitrogen bonds(GO:0016826)
0.3 4.6 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.3 2.6 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.3 1.3 GO:0009041 uridylate kinase activity(GO:0009041)
0.3 2.2 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.3 2.4 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.3 0.9 GO:0004145 diamine N-acetyltransferase activity(GO:0004145)
0.3 0.9 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.3 0.8 GO:0015229 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.2 3.1 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.2 1.3 GO:0032089 NACHT domain binding(GO:0032089)
0.2 0.6 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.2 0.6 GO:0016781 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.2 1.1 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.2 0.7 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.2 1.1 GO:0052656 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.2 0.5 GO:0036328 VEGF-C-activated receptor activity(GO:0036328)
0.2 1.1 GO:0047685 amine sulfotransferase activity(GO:0047685)
0.2 1.0 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.2 1.5 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.2 1.8 GO:0030274 LIM domain binding(GO:0030274)
0.2 1.1 GO:0008481 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.1 1.9 GO:0097016 L27 domain binding(GO:0097016)
0.1 0.4 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.1 0.6 GO:0035939 microsatellite binding(GO:0035939)
0.1 3.5 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 2.9 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.1 2.5 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.1 2.6 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 0.4 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.1 1.7 GO:0070324 thyroid hormone binding(GO:0070324)
0.1 0.8 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.1 2.9 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.1 0.5 GO:0015254 glycerol channel activity(GO:0015254)
0.1 1.3 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 0.3 GO:0030943 mitochondrion targeting sequence binding(GO:0030943)
0.1 0.9 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.1 0.4 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.1 0.6 GO:0005119 smoothened binding(GO:0005119)
0.1 2.8 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 0.7 GO:0070087 chromo shadow domain binding(GO:0070087)
0.1 0.4 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.1 0.4 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.1 2.2 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 0.7 GO:0050692 DBD domain binding(GO:0050692)
0.1 0.5 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.1 0.5 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.1 0.9 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.1 1.1 GO:0019957 C-C chemokine binding(GO:0019957)
0.1 0.2 GO:0033149 FFAT motif binding(GO:0033149)
0.1 0.3 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.1 1.0 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.1 0.9 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.1 1.6 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.1 0.5 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 0.5 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 1.7 GO:0043495 protein anchor(GO:0043495)
0.1 0.6 GO:0016842 amidine-lyase activity(GO:0016842)
0.1 1.1 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.1 2.6 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 0.2 GO:0005046 KDEL sequence binding(GO:0005046)
0.1 1.0 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 0.2 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.1 0.3 GO:0004994 somatostatin receptor activity(GO:0004994)
0.1 0.4 GO:0017002 activin-activated receptor activity(GO:0017002)
0.1 0.2 GO:1990699 palmitoleyl hydrolase activity(GO:1990699)
0.1 0.4 GO:1904047 histone methyltransferase activity (H3-K9 specific)(GO:0046974) S-adenosyl-L-methionine binding(GO:1904047)
0.0 1.4 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.4 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.7 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.4 GO:0034711 inhibin binding(GO:0034711)
0.0 0.4 GO:0019826 oxygen sensor activity(GO:0019826)
0.0 0.6 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.0 0.8 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 1.4 GO:0051787 misfolded protein binding(GO:0051787)
0.0 1.8 GO:0000217 DNA secondary structure binding(GO:0000217)
0.0 0.5 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.6 GO:0005057 receptor signaling protein activity(GO:0005057)
0.0 0.3 GO:0047820 D-glutamate cyclase activity(GO:0047820)
0.0 0.3 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.0 1.9 GO:0019213 deacetylase activity(GO:0019213)
0.0 0.2 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.7 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.2 GO:0038181 bile acid receptor activity(GO:0038181)
0.0 1.1 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.1 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
0.0 0.3 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.2 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.5 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.2 GO:0005110 frizzled-2 binding(GO:0005110)
0.0 1.9 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.7 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.7 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 1.9 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.4 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.2 GO:0015087 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.0 0.2 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.3 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.0 4.0 GO:0005518 collagen binding(GO:0005518)
0.0 1.9 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.8 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.6 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 1.1 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 2.2 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.2 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.2 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.0 0.1 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.0 0.7 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.2 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.3 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.6 GO:0031005 filamin binding(GO:0031005)
0.0 0.2 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.0 1.1 GO:0030507 spectrin binding(GO:0030507)
0.0 0.8 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 1.1 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 1.0 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.5 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.0 0.3 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.1 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.1 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 3.8 GO:0044325 ion channel binding(GO:0044325)
0.0 0.1 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 1.4 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.1 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.6 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.2 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.1 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.1 GO:0003696 satellite DNA binding(GO:0003696)
0.0 0.4 GO:0008301 DNA binding, bending(GO:0008301)
0.0 2.6 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.7 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.2 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.5 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.1 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.6 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.2 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.9 GO:0043022 ribosome binding(GO:0043022)
0.0 1.2 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.4 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.0 0.1 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.4 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 0.1 GO:0033592 RNA strand annealing activity(GO:0033592)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.5 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 2.0 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.1 2.8 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.1 1.7 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 2.3 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.6 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 1.0 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 2.5 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.7 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.9 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 1.7 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 1.5 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.5 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 4.7 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.3 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 2.9 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 1.4 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 1.0 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 0.8 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.1 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 1.7 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 0.4 PID ALK1 PATHWAY ALK1 signaling events
0.0 1.7 PID BMP PATHWAY BMP receptor signaling
0.0 1.1 PID AURORA A PATHWAY Aurora A signaling
0.0 1.5 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.9 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 1.1 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.2 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.6 ST GA13 PATHWAY G alpha 13 Pathway
0.0 0.8 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.5 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.4 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.1 ST STAT3 PATHWAY STAT3 Pathway
0.0 0.7 PID ATM PATHWAY ATM pathway
0.0 0.5 PID HIF2PATHWAY HIF-2-alpha transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.6 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.2 2.6 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1 1.1 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.1 2.5 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 3.1 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.1 2.8 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 1.9 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 1.5 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 2.2 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 0.8 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 2.9 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1 3.4 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 1.8 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 1.5 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.0 2.0 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.8 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 1.1 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 1.6 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.5 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 1.1 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.9 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.0 3.6 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.3 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 1.9 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 1.3 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.5 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.7 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.5 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 1.7 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.0 1.5 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 1.7 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.8 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.6 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 3.4 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.7 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 2.5 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 1.0 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.4 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.2 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.4 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 1.5 REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.0 0.6 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.2 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 1.7 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.4 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.3 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC