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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for ZNF232

Z-value: 0.70

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Transcription factors associated with ZNF232

Gene Symbol Gene ID Gene Info
ZNF232
ENSG00000167840.9 zinc finger protein 232

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZNF232hg19_v2_chr17_-_5026397_50264220.835.7e-06Click!

Activity profile of ZNF232 motif

Sorted Z-values of ZNF232 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr9_+_5231413 3.54 ENST00000239316.4
INSL4
insulin-like 4 (placenta)
chr2_-_225811747 3.02 ENST00000409592.3
DOCK10
dedicator of cytokinesis 10
chr1_-_204654826 2.30 ENST00000367177.3
LRRN2
leucine rich repeat neuronal 2
chr3_+_8543393 1.99 ENST00000157600.3
ENST00000415597.1
ENST00000535732.1
LMCD1
LIM and cysteine-rich domains 1
chr3_+_8543561 1.83 ENST00000397386.3
LMCD1
LIM and cysteine-rich domains 1
chr1_-_193074504 1.81 ENST00000367439.3
GLRX2
glutaredoxin 2
chr20_+_4129426 1.75 ENST00000339123.6
ENST00000305958.4
ENST00000278795.3
SMOX
spermine oxidase
chr3_+_8543533 1.68 ENST00000454244.1
LMCD1
LIM and cysteine-rich domains 1
chr19_-_14530112 1.56 ENST00000592632.1
ENST00000589675.1
DDX39A
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A
chrY_+_15016725 1.42 ENST00000336079.3
DDX3Y
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
chrY_+_15016013 1.34 ENST00000360160.4
ENST00000454054.1
DDX3Y
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
chr15_-_60771128 1.27 ENST00000558512.1
ENST00000561114.1
NARG2
NMDA receptor regulated 2
chr15_-_60771280 1.20 ENST00000560072.1
ENST00000560406.1
ENST00000560520.1
ENST00000261520.4
ENST00000439632.1
NARG2
NMDA receptor regulated 2
chr11_+_74811578 1.17 ENST00000531713.1
SLCO2B1
solute carrier organic anion transporter family, member 2B1
chr15_-_56757329 1.12 ENST00000260453.3
MNS1
meiosis-specific nuclear structural 1
chr2_+_74425689 1.05 ENST00000394053.2
ENST00000409804.1
ENST00000264090.4
ENST00000394050.3
ENST00000409601.1
MTHFD2
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
chr7_-_56101826 1.05 ENST00000421626.1
PSPH
phosphoserine phosphatase
chr13_-_30160925 0.87 ENST00000450494.1
SLC7A1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr14_-_20922960 0.85 ENST00000553640.1
ENST00000488532.2
OSGEP
O-sialoglycoprotein endopeptidase
chr1_+_156105878 0.82 ENST00000508500.1
LMNA
lamin A/C
chr19_-_14529847 0.79 ENST00000590239.1
ENST00000590696.1
ENST00000591275.1
ENST00000586993.1
DDX39A
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A
chr5_-_180076613 0.72 ENST00000261937.6
ENST00000393347.3
FLT4
fms-related tyrosine kinase 4
chr2_-_113522177 0.64 ENST00000541405.1
CKAP2L
cytoskeleton associated protein 2-like
chr2_+_234826016 0.59 ENST00000324695.4
ENST00000433712.2
TRPM8
transient receptor potential cation channel, subfamily M, member 8
chr16_+_30662085 0.58 ENST00000569864.1
PRR14
proline rich 14
chr11_-_18127566 0.57 ENST00000532452.1
ENST00000530180.1
ENST00000300013.4
ENST00000529318.1
ENST00000524803.1
SAAL1
serum amyloid A-like 1
chr20_-_33732952 0.52 ENST00000541621.1
EDEM2
ER degradation enhancer, mannosidase alpha-like 2
chr2_-_113522248 0.43 ENST00000302450.6
CKAP2L
cytoskeleton associated protein 2-like
chr5_-_180076580 0.39 ENST00000502649.1
FLT4
fms-related tyrosine kinase 4
chr4_+_185570871 0.33 ENST00000512834.1
PRIMPOL
primase and polymerase (DNA-directed)
chr7_+_1609765 0.33 ENST00000437964.1
ENST00000533935.1
ENST00000532358.1
ENST00000524978.1
PSMG3-AS1
PSMG3 antisense RNA 1 (head to head)
chr2_-_74619152 0.29 ENST00000440727.1
ENST00000409240.1
DCTN1
dynactin 1
chr7_+_1609694 0.29 ENST00000437621.2
ENST00000457484.2
PSMG3-AS1
PSMG3 antisense RNA 1 (head to head)
chr4_-_84255935 0.28 ENST00000513463.1
HPSE
heparanase
chr10_+_134150835 0.28 ENST00000432555.2
LRRC27
leucine rich repeat containing 27
chr9_-_115480303 0.27 ENST00000374234.1
ENST00000374238.1
ENST00000374236.1
ENST00000374242.4
INIP
INTS3 and NABP interacting protein
chr6_-_46922659 0.27 ENST00000265417.7
GPR116
G protein-coupled receptor 116
chr6_-_26056695 0.25 ENST00000343677.2
HIST1H1C
histone cluster 1, H1c
chr19_-_10491130 0.24 ENST00000530829.1
ENST00000529370.1
TYK2
tyrosine kinase 2
chr7_-_1609591 0.24 ENST00000288607.2
ENST00000404674.3
PSMG3
proteasome (prosome, macropain) assembly chaperone 3
chr2_-_74618964 0.23 ENST00000417090.1
ENST00000409868.1
DCTN1
dynactin 1
chrX_-_130423386 0.23 ENST00000370903.3
IGSF1
immunoglobulin superfamily, member 1
chr6_+_109416684 0.23 ENST00000521522.1
ENST00000524064.1
ENST00000522608.1
ENST00000521503.1
ENST00000519407.1
ENST00000519095.1
ENST00000368968.2
ENST00000522490.1
ENST00000523209.1
ENST00000368970.2
ENST00000520883.1
ENST00000523787.1
CEP57L1
centrosomal protein 57kDa-like 1
chr19_+_18043810 0.20 ENST00000445755.2
CCDC124
coiled-coil domain containing 124
chr9_-_107367951 0.19 ENST00000542196.1
OR13C2
olfactory receptor, family 13, subfamily C, member 2
chr17_+_40458130 0.18 ENST00000587646.1
STAT5A
signal transducer and activator of transcription 5A
chr19_-_11545920 0.16 ENST00000356392.4
ENST00000591179.1
CCDC151
coiled-coil domain containing 151
chr17_-_6915646 0.16 ENST00000574377.1
ENST00000399541.2
ENST00000399540.2
ENST00000575727.1
ENST00000573939.1
AC027763.2
Uncharacterized protein
chr1_-_53686261 0.15 ENST00000294360.4
C1orf123
chromosome 1 open reading frame 123
chr3_-_185216766 0.15 ENST00000296254.3
TMEM41A
transmembrane protein 41A
chr6_+_109416313 0.14 ENST00000521277.1
ENST00000517392.1
ENST00000407272.1
ENST00000336977.4
ENST00000519286.1
ENST00000518329.1
ENST00000522461.1
ENST00000518853.1
CEP57L1
centrosomal protein 57kDa-like 1
chr4_-_88450612 0.13 ENST00000418378.1
ENST00000282470.6
SPARCL1
SPARC-like 1 (hevin)
chr7_+_116654935 0.12 ENST00000432298.1
ENST00000422922.1
ST7
suppression of tumorigenicity 7
chr1_+_182419261 0.12 ENST00000294854.8
ENST00000542961.1
RGSL1
regulator of G-protein signaling like 1
chr3_-_123304017 0.12 ENST00000383657.5
PTPLB
protein tyrosine phosphatase-like (proline instead of catalytic arginine), member b
chr2_+_232316906 0.11 ENST00000370380.2
AC017104.2
Uncharacterized protein
chr2_+_29353520 0.11 ENST00000438819.1
CLIP4
CAP-GLY domain containing linker protein family, member 4
chr2_+_228735763 0.10 ENST00000373666.2
DAW1
dynein assembly factor with WDR repeat domains 1
chr15_-_79383102 0.10 ENST00000558480.2
ENST00000419573.3
RASGRF1
Ras protein-specific guanine nucleotide-releasing factor 1
chr15_-_74374891 0.08 ENST00000290438.3
GOLGA6A
golgin A6 family, member A
chr1_-_16556038 0.07 ENST00000375605.2
C1orf134
chromosome 1 open reading frame 134
chr7_+_116654958 0.06 ENST00000449366.1
ST7
suppression of tumorigenicity 7
chr14_+_22600515 0.05 ENST00000390456.3
TRAV8-7
T cell receptor alpha variable 8-7 (non-functional)
chr5_+_177435986 0.04 ENST00000398106.2
FAM153C
family with sequence similarity 153, member C
chr11_+_66276550 0.03 ENST00000419755.3
CTD-3074O7.11
Bardet-Biedl syndrome 1 protein
chr9_+_117085336 0.03 ENST00000259396.8
ENST00000538816.1
ORM1
orosomucoid 1
chr11_+_123900297 0.02 ENST00000431524.1
OR10G8
olfactory receptor, family 10, subfamily G, member 8
chr19_-_10491234 0.01 ENST00000524462.1
ENST00000531836.1
ENST00000525621.1
TYK2
tyrosine kinase 2
chr7_+_142919130 0.01 ENST00000408947.3
TAS2R40
taste receptor, type 2, member 40

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF232

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.8 GO:0046208 spermine catabolic process(GO:0046208)
0.2 0.8 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.2 5.5 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.2 3.0 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.2 1.8 GO:0042262 DNA protection(GO:0042262)
0.2 0.8 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.1 0.9 GO:1903826 arginine transmembrane transport(GO:1903826)
0.1 0.5 GO:0036509 trimming of terminal mannose on B branch(GO:0036509) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512)
0.1 0.6 GO:0050955 thermoception(GO:0050955)
0.1 5.1 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.1 1.0 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.1 0.5 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.1 0.3 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.1 1.1 GO:0090037 positive regulation of protein kinase C signaling(GO:0090037)
0.0 1.1 GO:0070986 left/right axis specification(GO:0070986)
0.0 0.3 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.0 0.2 GO:0000255 allantoin metabolic process(GO:0000255)
0.0 1.0 GO:0046653 tetrahydrofolate metabolic process(GO:0046653)
0.0 0.3 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 1.2 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 3.5 GO:0007565 female pregnancy(GO:0007565)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.1 0.8 GO:0005638 lamin filament(GO:0005638)
0.0 0.3 GO:0070876 SOSS complex(GO:0070876)
0.0 0.5 GO:0005869 dynactin complex(GO:0005869)
0.0 0.5 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0052895 norspermine:oxygen oxidoreductase activity(GO:0052894) N1-acetylspermine:oxygen oxidoreductase (N1-acetylspermidine-forming) activity(GO:0052895)
0.4 1.1 GO:0036328 VEGF-C-activated receptor activity(GO:0036328)
0.3 1.0 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.3 0.8 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.2 1.8 GO:0030613 oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614)
0.1 1.0 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.1 0.9 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.1 0.3 GO:0003896 DNA primase activity(GO:0003896)
0.1 0.3 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.1 3.5 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 5.1 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.0 1.2 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.5 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.2 GO:0005131 growth hormone receptor binding(GO:0005131)
0.0 0.2 GO:0034711 inhibin binding(GO:0034711)
0.0 5.5 GO:0003714 transcription corepressor activity(GO:0003714)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 3.0 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.2 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.2 PID IL5 PATHWAY IL5-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 1.1 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 1.2 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 1.0 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.5 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.2 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 1.4 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 3.0 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.9 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.3 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation