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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for ZNF274

Z-value: 0.64

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Transcription factors associated with ZNF274

Gene Symbol Gene ID Gene Info
ENSG00000171606.13 zinc finger protein 274

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZNF274hg19_v2_chr19_+_58694396_58694485-0.252.8e-01Click!

Activity profile of ZNF274 motif

Sorted Z-values of ZNF274 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_56109119 3.41 ENST00000587678.1
FLT3-interacting zinc finger 1
chr6_-_127780510 2.85 ENST00000487331.2
ENST00000483725.3
KIAA0408
chr12_+_113344755 1.86 ENST00000550883.1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr8_-_19540266 1.79 ENST00000311540.4
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr8_-_19540086 1.78 ENST00000332246.6
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr19_+_6887571 1.66 ENST00000250572.8
ENST00000381407.5
ENST00000312053.4
ENST00000450315.3
ENST00000381404.4
egf-like module containing, mucin-like, hormone receptor-like 1
chr1_+_45205478 1.37 ENST00000452259.1
ENST00000372224.4
kinesin family member 2C
chr1_+_45205498 1.31 ENST00000372218.4
kinesin family member 2C
chr4_+_15704573 1.27 ENST00000265016.4
bone marrow stromal cell antigen 1
chr15_+_89164560 1.25 ENST00000379231.3
ENST00000559528.1
apoptosis enhancing nuclease
chr4_+_15704679 1.24 ENST00000382346.3
bone marrow stromal cell antigen 1
chr7_-_73038822 0.99 ENST00000414749.2
ENST00000429400.2
ENST00000434326.1
MLX interacting protein-like
chr20_+_60174827 0.90 ENST00000543233.1
cadherin 4, type 1, R-cadherin (retinal)
chr15_+_89164520 0.85 ENST00000332810.3
apoptosis enhancing nuclease
chrX_+_52920336 0.81 ENST00000452154.2
family with sequence similarity 156, member B
chr6_+_30687978 0.79 ENST00000327892.8
ENST00000435534.1
tubulin, beta class I
chr16_+_29818857 0.74 ENST00000567444.1
MYC-associated zinc finger protein (purine-binding transcription factor)
chr17_-_73636019 0.68 ENST00000580707.1
RecQ protein-like 5
chr12_-_89919965 0.63 ENST00000548729.1
POC1B-GALNT4 readthrough
chr2_+_178977143 0.62 ENST00000286070.5
RNA binding motif protein 45
chr2_+_9696028 0.59 ENST00000607241.1
RP11-214N9.1
chr19_+_46498704 0.59 ENST00000595358.1
ENST00000594672.1
ENST00000536603.1
coiled-coil domain containing 61
chr12_-_54653313 0.58 ENST00000550411.1
ENST00000439541.2
chromobox homolog 5
chr16_+_29819096 0.58 ENST00000568411.1
ENST00000563012.1
ENST00000562557.1
MYC-associated zinc finger protein (purine-binding transcription factor)
chrX_+_119737806 0.53 ENST00000371317.5
malignant T cell amplified sequence 1
chr3_-_38992052 0.46 ENST00000302328.3
ENST00000450244.1
ENST00000444237.2
sodium channel, voltage-gated, type XI, alpha subunit
chr12_-_89920030 0.39 ENST00000413530.1
ENST00000547474.1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4)
POC1B-GALNT4 readthrough
chr17_+_41132564 0.35 ENST00000361677.1
ENST00000589705.1
RUN domain containing 1
chr18_+_9103957 0.34 ENST00000400033.1
NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa
chr5_+_32531893 0.33 ENST00000512913.1
SUB1 homolog (S. cerevisiae)
chr19_+_7584088 0.33 ENST00000394341.2
zinc finger protein 358
chr5_+_121465207 0.29 ENST00000296600.4
zinc finger protein 474
chr22_+_39353527 0.29 ENST00000249116.2
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A
chr17_-_41132410 0.29 ENST00000409446.3
ENST00000453594.1
ENST00000409399.1
ENST00000421990.2
prostaglandin E synthase 3 (cytosolic)-like
PTGES3L-AARSD1 readthrough
chr19_+_41949054 0.28 ENST00000378187.2
chromosome 19 open reading frame 69
chr16_+_31470179 0.26 ENST00000538189.1
ENST00000268314.4
armadillo repeat containing 5
chr2_+_11864458 0.25 ENST00000396098.1
ENST00000396099.1
ENST00000425416.2
lipin 1
chr5_-_173043591 0.24 ENST00000285908.5
ENST00000480951.1
ENST00000311086.4
biorientation of chromosomes in cell division 1
chr3_-_38991853 0.24 ENST00000456224.3
sodium channel, voltage-gated, type XI, alpha subunit
chr6_+_31553978 0.23 ENST00000376096.1
ENST00000376099.1
ENST00000376110.3
leukocyte specific transcript 1
chr5_+_121465234 0.23 ENST00000504912.1
ENST00000505843.1
zinc finger protein 474
chr16_+_31470143 0.23 ENST00000457010.2
ENST00000563544.1
armadillo repeat containing 5
chr19_+_4153598 0.21 ENST00000078445.2
ENST00000252587.3
ENST00000595923.1
ENST00000602257.1
ENST00000602147.1
cAMP responsive element binding protein 3-like 3
chr3_-_160117301 0.20 ENST00000326448.7
ENST00000498409.1
ENST00000475677.1
ENST00000478536.1
intraflagellar transport 80 homolog (Chlamydomonas)
chr5_-_74162739 0.18 ENST00000513277.1
family with sequence similarity 169, member A
chr6_+_31553901 0.17 ENST00000418507.2
ENST00000438075.2
ENST00000376100.3
ENST00000376111.4
leukocyte specific transcript 1
chr4_-_121993673 0.14 ENST00000379692.4
neuron-derived neurotrophic factor
chr13_-_74993252 0.12 ENST00000325811.1
Uncharacterized protein
chr19_+_6135646 0.11 ENST00000588304.1
ENST00000588485.1
ENST00000588722.1
ENST00000591403.1
ENST00000586696.1
ENST00000589401.1
ENST00000252669.5
acyl-CoA synthetase bubblegum family member 2
chr17_-_7145106 0.09 ENST00000577035.1
GABA(A) receptor-associated protein
chr5_-_74162605 0.08 ENST00000389156.4
ENST00000510496.1
ENST00000380515.3
family with sequence similarity 169, member A
chr9_+_125512019 0.08 ENST00000373684.1
ENST00000304720.2
olfactory receptor, family 1, subfamily L, member 6
chr11_+_59705928 0.06 ENST00000398992.1
oocyte secreted protein 1
chr14_-_24047965 0.05 ENST00000397118.3
ENST00000356300.4
junctophilin 4
chr16_+_29127282 0.04 ENST00000562902.1
RP11-426C22.5
chr1_+_47533160 0.02 ENST00000334194.3
cytochrome P450, family 4, subfamily Z, polypeptide 1
chr20_-_1638408 0.01 ENST00000303415.3
ENST00000381583.2
signal-regulatory protein gamma
chr20_-_1638360 0.01 ENST00000216927.4
ENST00000344103.4
signal-regulatory protein gamma
chr2_-_42991257 0.00 ENST00000378661.2
oxoeicosanoid (OXE) receptor 1

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF274

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.6 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.2 2.7 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.2 0.5 GO:0002188 translation reinitiation(GO:0002188)
0.1 0.7 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.1 1.0 GO:0090324 negative regulation of oxidative phosphorylation(GO:0090324)
0.1 2.5 GO:0090022 regulation of neutrophil chemotaxis(GO:0090022)
0.0 0.3 GO:0070383 DNA cytosine deamination(GO:0070383)
0.0 0.2 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 2.1 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0 1.9 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.2 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0 0.7 GO:0051930 regulation of sensory perception of pain(GO:0051930) regulation of sensory perception(GO:0051931)
0.0 0.9 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.5 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1 0.3 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.0 0.8 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 2.7 GO:0035371 microtubule plus-end(GO:0035371)
0.0 3.6 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.6 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.7 GO:0001518 voltage-gated sodium channel complex(GO:0001518)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.5 GO:0050135 NAD(P)+ nucleosidase activity(GO:0050135)
0.5 3.6 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
0.2 2.7 GO:0019237 centromeric DNA binding(GO:0019237)
0.2 1.9 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1 0.7 GO:0009378 four-way junction helicase activity(GO:0009378)
0.1 0.3 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
0.0 0.2 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 3.4 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.8 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.7 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 2.1 GO:0004527 exonuclease activity(GO:0004527)
0.0 0.3 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 3.3 PID AURORA B PATHWAY Aurora B signaling
0.0 2.1 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.6 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.1 2.7 REACTOME KINESINS Genes involved in Kinesins
0.0 1.9 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.9 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 1.7 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)