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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for ZNF350

Z-value: 0.32

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Transcription factors associated with ZNF350

Gene Symbol Gene ID Gene Info
ZNF350
ENSG00000256683.2 zinc finger protein 350

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZNF350hg19_v2_chr19_-_52489923_52490113-0.282.3e-01Click!

Activity profile of ZNF350 motif

Sorted Z-values of ZNF350 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr17_+_68165657 0.24 ENST00000243457.3
KCNJ2
potassium inwardly-rectifying channel, subfamily J, member 2
chr16_-_74734742 0.21 ENST00000308807.7
ENST00000573267.1
MLKL
mixed lineage kinase domain-like
chr16_+_69600058 0.19 ENST00000393742.2
NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr11_-_64511575 0.18 ENST00000431822.1
ENST00000377486.3
ENST00000394432.3
RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr19_+_35532612 0.18 ENST00000600390.1
ENST00000597419.1
HPN
hepsin
chr11_-_63381925 0.18 ENST00000415826.1
PLA2G16
phospholipase A2, group XVI
chr11_-_63381823 0.16 ENST00000323646.5
PLA2G16
phospholipase A2, group XVI
chr8_-_12612962 0.15 ENST00000398246.3
LONRF1
LON peptidase N-terminal domain and ring finger 1
chr16_-_74734672 0.14 ENST00000306247.7
ENST00000575686.1
MLKL
mixed lineage kinase domain-like
chr15_-_57210769 0.13 ENST00000559000.1
ZNF280D
zinc finger protein 280D
chr11_+_48002076 0.12 ENST00000418331.2
ENST00000440289.2
PTPRJ
protein tyrosine phosphatase, receptor type, J
chr4_-_174255400 0.12 ENST00000506267.1
HMGB2
high mobility group box 2
chr4_-_174255536 0.12 ENST00000446922.2
HMGB2
high mobility group box 2
chr5_+_41904431 0.12 ENST00000381647.2
C5orf51
chromosome 5 open reading frame 51
chr11_+_48002279 0.12 ENST00000534219.1
ENST00000527952.1
PTPRJ
protein tyrosine phosphatase, receptor type, J
chr11_+_57531292 0.12 ENST00000524579.1
CTNND1
catenin (cadherin-associated protein), delta 1
chr13_-_96329048 0.11 ENST00000606011.1
ENST00000499499.2
DNAJC3-AS1
DNAJC3 antisense RNA 1 (head to head)
chr3_-_155524049 0.11 ENST00000534941.1
ENST00000340171.2
C3orf33
chromosome 3 open reading frame 33
chr4_-_174256276 0.11 ENST00000296503.5
HMGB2
high mobility group box 2
chr3_-_128212016 0.10 ENST00000498200.1
ENST00000341105.2
GATA2
GATA binding protein 2
chr16_+_69600209 0.10 ENST00000566899.1
NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr1_+_63788730 0.10 ENST00000371116.2
FOXD3
forkhead box D3
chr11_-_414948 0.10 ENST00000530494.1
ENST00000528209.1
ENST00000431843.2
ENST00000528058.1
SIGIRR
single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
chr2_-_241759622 0.09 ENST00000320389.7
ENST00000498729.2
KIF1A
kinesin family member 1A
chr10_+_69644404 0.09 ENST00000212015.6
SIRT1
sirtuin 1
chr17_+_19030782 0.09 ENST00000344415.4
ENST00000577213.1
GRAPL
GRB2-related adaptor protein-like
chr17_-_18950310 0.09 ENST00000573099.1
GRAP
GRB2-related adaptor protein
chr11_-_64511789 0.09 ENST00000419843.1
ENST00000394430.1
RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr1_+_173446405 0.09 ENST00000340385.5
PRDX6
peroxiredoxin 6
chr3_-_118753626 0.08 ENST00000489689.1
IGSF11
immunoglobulin superfamily, member 11
chr16_+_31225337 0.08 ENST00000322122.3
TRIM72
tripartite motif containing 72
chr11_-_112034831 0.08 ENST00000280357.7
IL18
interleukin 18 (interferon-gamma-inducing factor)
chr11_-_112034803 0.08 ENST00000528832.1
IL18
interleukin 18 (interferon-gamma-inducing factor)
chr3_+_113775594 0.07 ENST00000479882.1
ENST00000493014.1
QTRTD1
queuine tRNA-ribosyltransferase domain containing 1
chr2_-_219925189 0.07 ENST00000295731.6
IHH
indian hedgehog
chr3_-_118753716 0.07 ENST00000393775.2
IGSF11
immunoglobulin superfamily, member 11
chr12_+_113376157 0.07 ENST00000228928.7
OAS3
2'-5'-oligoadenylate synthetase 3, 100kDa
chr1_+_204494618 0.07 ENST00000367180.1
ENST00000391947.2
MDM4
Mdm4 p53 binding protein homolog (mouse)
chr11_-_45687128 0.07 ENST00000308064.2
CHST1
carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
chr11_-_68671264 0.07 ENST00000362034.2
MRPL21
mitochondrial ribosomal protein L21
chr18_+_77155942 0.07 ENST00000397790.2
NFATC1
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr11_-_112034780 0.07 ENST00000524595.1
IL18
interleukin 18 (interferon-gamma-inducing factor)
chr1_+_29213678 0.07 ENST00000347529.3
EPB41
erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)
chr2_+_120517174 0.07 ENST00000263708.2
PTPN4
protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
chr10_+_94821021 0.07 ENST00000285949.5
CYP26C1
cytochrome P450, family 26, subfamily C, polypeptide 1
chr1_-_204654481 0.06 ENST00000367176.3
LRRN2
leucine rich repeat neuronal 2
chr1_+_156611900 0.06 ENST00000457777.2
ENST00000424639.1
BCAN
brevican
chr15_-_65477637 0.06 ENST00000300107.3
CLPX
caseinolytic mitochondrial matrix peptidase chaperone subunit
chr3_+_140947563 0.06 ENST00000505013.1
ACPL2
acid phosphatase-like 2
chr4_+_75858318 0.06 ENST00000307428.7
PARM1
prostate androgen-regulated mucin-like protein 1
chr16_-_46865047 0.06 ENST00000394806.2
C16orf87
chromosome 16 open reading frame 87
chr12_-_53228079 0.06 ENST00000330553.5
KRT79
keratin 79
chr12_+_113376249 0.06 ENST00000551007.1
ENST00000548514.1
OAS3
2'-5'-oligoadenylate synthetase 3, 100kDa
chr17_-_6554877 0.06 ENST00000225728.3
ENST00000575197.1
MED31
mediator complex subunit 31
chr10_-_97175444 0.06 ENST00000486141.2
SORBS1
sorbin and SH3 domain containing 1
chr2_-_106810783 0.06 ENST00000283148.7
UXS1
UDP-glucuronate decarboxylase 1
chr5_-_107717058 0.06 ENST00000359660.5
FBXL17
F-box and leucine-rich repeat protein 17
chr3_-_118753566 0.06 ENST00000491903.1
IGSF11
immunoglobulin superfamily, member 11
chr11_-_62437486 0.06 ENST00000528115.1
C11orf48
chromosome 11 open reading frame 48
chr1_-_98510843 0.06 ENST00000413670.2
ENST00000538428.1
MIR137HG
MIR137 host gene (non-protein coding)
chr10_-_120938303 0.06 ENST00000356951.3
ENST00000298510.2
PRDX3
peroxiredoxin 3
chr1_-_247094628 0.06 ENST00000366508.1
ENST00000326225.3
ENST00000391829.2
AHCTF1
AT hook containing transcription factor 1
chr16_-_46865286 0.05 ENST00000285697.4
C16orf87
chromosome 16 open reading frame 87
chr17_-_18950950 0.05 ENST00000284154.5
GRAP
GRB2-related adaptor protein
chr1_-_155948218 0.05 ENST00000313667.4
ARHGEF2
Rho/Rac guanine nucleotide exchange factor (GEF) 2
chr4_+_75858290 0.05 ENST00000513238.1
PARM1
prostate androgen-regulated mucin-like protein 1
chr1_-_51425902 0.05 ENST00000396153.2
FAF1
Fas (TNFRSF6) associated factor 1
chr8_+_22414182 0.05 ENST00000524057.1
SORBS3
sorbin and SH3 domain containing 3
chr14_+_96671016 0.05 ENST00000542454.2
ENST00000554311.1
ENST00000306005.3
ENST00000539359.1
ENST00000553811.1
BDKRB2
RP11-404P21.8
bradykinin receptor B2
Uncharacterized protein
chr9_-_99616642 0.05 ENST00000478850.1
ENST00000481138.1
ZNF782
zinc finger protein 782
chr11_-_68671244 0.05 ENST00000567045.1
ENST00000450904.2
MRPL21
mitochondrial ribosomal protein L21
chr3_+_14219858 0.05 ENST00000306024.3
LSM3
LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr11_+_327171 0.05 ENST00000534483.1
ENST00000524824.1
ENST00000531076.1
RP11-326C3.12
RP11-326C3.12
chr19_+_2977444 0.05 ENST00000246112.4
ENST00000453329.1
ENST00000482627.1
ENST00000452088.1
TLE6
transducin-like enhancer of split 6 (E(sp1) homolog, Drosophila)
chr11_+_64323156 0.05 ENST00000377585.3
SLC22A11
solute carrier family 22 (organic anion/urate transporter), member 11
chr15_+_57210961 0.05 ENST00000557843.1
TCF12
transcription factor 12
chr2_-_21266935 0.05 ENST00000233242.1
APOB
apolipoprotein B
chr14_+_96829814 0.05 ENST00000555181.1
ENST00000553699.1
ENST00000554182.1
GSKIP
GSK3B interacting protein
chr17_+_6554971 0.04 ENST00000391428.2
C17orf100
chromosome 17 open reading frame 100
chr18_+_77155856 0.04 ENST00000253506.5
ENST00000591814.1
NFATC1
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr1_+_22970119 0.04 ENST00000374640.4
ENST00000374639.3
ENST00000374637.1
C1QC
complement component 1, q subcomponent, C chain
chr3_+_113775576 0.04 ENST00000485050.1
ENST00000281273.4
QTRTD1
queuine tRNA-ribosyltransferase domain containing 1
chr16_-_46864955 0.04 ENST00000565112.1
C16orf87
chromosome 16 open reading frame 87
chr15_+_57210818 0.04 ENST00000438423.2
ENST00000267811.5
ENST00000452095.2
ENST00000559609.1
ENST00000333725.5
TCF12
transcription factor 12
chr17_-_935036 0.04 ENST00000572441.1
ENST00000543210.2
ABR
active BCR-related
chr11_+_64323428 0.04 ENST00000377581.3
SLC22A11
solute carrier family 22 (organic anion/urate transporter), member 11
chr2_+_177025619 0.04 ENST00000410016.1
HOXD3
homeobox D3
chr9_-_92051391 0.04 ENST00000420681.2
SEMA4D
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
chr10_-_12084770 0.04 ENST00000357604.5
UPF2
UPF2 regulator of nonsense transcripts homolog (yeast)
chr19_-_4535233 0.04 ENST00000381848.3
ENST00000588887.1
ENST00000586133.1
PLIN5
perilipin 5
chr2_+_233497931 0.04 ENST00000264059.3
EFHD1
EF-hand domain family, member D1
chr1_-_166135952 0.04 ENST00000354422.3
FAM78B
family with sequence similarity 78, member B
chr2_-_21266816 0.04 ENST00000399256.4
APOB
apolipoprotein B
chr1_-_200379180 0.04 ENST00000294740.3
ZNF281
zinc finger protein 281
chr3_+_50229037 0.04 ENST00000232461.3
ENST00000433068.1
GNAT1
guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1
chr3_-_113775328 0.04 ENST00000483766.1
ENST00000545063.1
ENST00000491000.1
ENST00000295878.3
KIAA1407
KIAA1407
chr12_+_131438443 0.04 ENST00000261654.5
GPR133
G protein-coupled receptor 133
chr4_-_76008706 0.04 ENST00000562355.1
ENST00000563602.1
RP11-44F21.5
RP11-44F21.5
chr18_-_5892103 0.03 ENST00000383490.2
TMEM200C
transmembrane protein 200C
chr2_+_238600788 0.03 ENST00000289175.6
ENST00000244815.5
LRRFIP1
leucine rich repeat (in FLII) interacting protein 1
chr2_+_120302041 0.03 ENST00000442513.3
ENST00000413369.3
PCDP1
Primary ciliary dyskinesia protein 1
chr1_-_166136187 0.03 ENST00000338353.3
FAM78B
family with sequence similarity 78, member B
chr2_+_132286754 0.03 ENST00000434330.1
CCDC74A
coiled-coil domain containing 74A
chr11_-_6790286 0.03 ENST00000338569.2
OR2AG2
olfactory receptor, family 2, subfamily AG, member 2
chr22_+_26565440 0.03 ENST00000404234.3
ENST00000529632.2
ENST00000360929.3
ENST00000248933.6
ENST00000343706.4
SEZ6L
seizure related 6 homolog (mouse)-like
chr20_-_31071309 0.03 ENST00000326071.4
C20orf112
chromosome 20 open reading frame 112
chr11_-_119217365 0.03 ENST00000360167.4
ENST00000555262.1
ENST00000449574.2
ENST00000445041.2
MFRP
C1QTNF5
membrane frizzled-related protein
C1q and tumor necrosis factor related protein 5
chr20_+_44035200 0.03 ENST00000372717.1
ENST00000360981.4
DBNDD2
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr2_-_157198860 0.03 ENST00000409572.1
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr3_-_118753792 0.03 ENST00000480431.1
IGSF11
immunoglobulin superfamily, member 11
chr17_+_48624450 0.03 ENST00000006658.6
ENST00000356488.4
ENST00000393244.3
SPATA20
spermatogenesis associated 20
chr9_+_34992846 0.03 ENST00000443266.1
DNAJB5
DnaJ (Hsp40) homolog, subfamily B, member 5
chr2_-_166650700 0.03 ENST00000422973.1
GALNT3
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3)
chr2_-_106810742 0.03 ENST00000409501.3
ENST00000428048.2
ENST00000441952.1
ENST00000457835.1
ENST00000540130.1
UXS1
UDP-glucuronate decarboxylase 1
chr2_+_120301997 0.02 ENST00000602047.1
PCDP1
Primary ciliary dyskinesia protein 1
chr10_+_7860460 0.02 ENST00000344293.5
TAF3
TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa
chrX_-_17878827 0.02 ENST00000360011.1
RAI2
retinoic acid induced 2
chr21_-_30365136 0.02 ENST00000361371.5
ENST00000389194.2
ENST00000389195.2
LTN1
listerin E3 ubiquitin protein ligase 1
chr3_+_100328433 0.02 ENST00000273352.3
GPR128
G protein-coupled receptor 128
chrX_+_120181457 0.02 ENST00000328078.1
GLUD2
glutamate dehydrogenase 2
chr2_+_120302055 0.02 ENST00000598644.1
PCDP1
Primary ciliary dyskinesia protein 1
chr1_+_156611960 0.02 ENST00000361588.5
BCAN
brevican
chr8_+_144295067 0.02 ENST00000330824.2
GPIHBP1
glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1
chr16_+_2479390 0.02 ENST00000397066.4
CCNF
cyclin F
chr13_-_99738867 0.02 ENST00000427887.1
DOCK9
dedicator of cytokinesis 9
chr1_+_12123414 0.02 ENST00000263932.2
TNFRSF8
tumor necrosis factor receptor superfamily, member 8
chr1_+_156611704 0.02 ENST00000329117.5
BCAN
brevican
chr12_+_109569155 0.02 ENST00000539864.1
ACACB
acetyl-CoA carboxylase beta
chr1_+_12123463 0.02 ENST00000417814.2
TNFRSF8
tumor necrosis factor receptor superfamily, member 8
chr17_-_73511504 0.02 ENST00000581870.1
CASKIN2
CASK interacting protein 2
chr11_-_9113093 0.02 ENST00000450649.2
SCUBE2
signal peptide, CUB domain, EGF-like 2
chr5_-_93077293 0.02 ENST00000510627.4
POU5F2
POU domain class 5, transcription factor 2
chr17_+_1173853 0.01 ENST00000391429.1
BHLHA9
basic helix-loop-helix family, member a9
chr8_+_86157699 0.01 ENST00000321764.3
CA13
carbonic anhydrase XIII
chr10_-_94003003 0.01 ENST00000412050.4
CPEB3
cytoplasmic polyadenylation element binding protein 3
chr17_-_79881408 0.01 ENST00000392366.3
MAFG
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
chr11_-_62473706 0.01 ENST00000403550.1
BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr17_-_48207115 0.01 ENST00000511964.1
SAMD14
sterile alpha motif domain containing 14
chr3_-_151176497 0.01 ENST00000282466.3
IGSF10
immunoglobulin superfamily, member 10
chr11_-_62473776 0.01 ENST00000278893.7
ENST00000407022.3
ENST00000421906.1
BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr11_-_64703354 0.01 ENST00000532246.1
ENST00000279168.2
GPHA2
glycoprotein hormone alpha 2
chr13_-_37633567 0.01 ENST00000464744.1
SUPT20H
suppressor of Ty 20 homolog (S. cerevisiae)
chr4_+_6784401 0.01 ENST00000425103.1
ENST00000307659.5
KIAA0232
KIAA0232
chr1_+_202792385 0.01 ENST00000549576.1
RP11-480I12.4
Putative inactive alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase-like protein LOC641515
chr17_-_39597173 0.01 ENST00000246646.3
KRT38
keratin 38
chr11_-_9113137 0.01 ENST00000520467.1
ENST00000309263.3
ENST00000457346.2
SCUBE2
signal peptide, CUB domain, EGF-like 2
chr11_-_62473684 0.01 ENST00000448568.2
BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr4_-_5991545 0.01 ENST00000531445.1
C4orf50
chromosome 4 open reading frame 50
chr2_+_132287237 0.01 ENST00000467992.2
CCDC74A
coiled-coil domain containing 74A
chr11_+_7041677 0.01 ENST00000299481.4
NLRP14
NLR family, pyrin domain containing 14
chr4_+_120133791 0.01 ENST00000274030.6
USP53
ubiquitin specific peptidase 53
chr11_-_8954491 0.00 ENST00000526227.1
ENST00000525780.1
ENST00000326053.5
C11orf16
chromosome 11 open reading frame 16
chr14_-_94254821 0.00 ENST00000393140.1
PRIMA1
proline rich membrane anchor 1
chr4_-_99578776 0.00 ENST00000515287.1
TSPAN5
tetraspanin 5
chr9_-_92051354 0.00 ENST00000418828.1
SEMA4D
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
chr6_+_36973406 0.00 ENST00000274963.8
FGD2
FYVE, RhoGEF and PH domain containing 2
chrX_-_47479246 0.00 ENST00000295987.7
ENST00000340666.4
SYN1
synapsin I

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF350

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0097195 pilomotor reflex(GO:0097195)
0.1 0.2 GO:0042231 interleukin-13 biosynthetic process(GO:0042231)
0.0 0.2 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.0 0.5 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.0 0.3 GO:0046485 ether lipid metabolic process(GO:0046485)
0.0 0.1 GO:1990619 histone H3-K9 deacetylation(GO:1990619)
0.0 0.1 GO:0033319 UDP-D-xylose metabolic process(GO:0033319) UDP-D-xylose biosynthetic process(GO:0033320)
0.0 0.1 GO:0016539 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.0 0.1 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.0 0.1 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.0 0.1 GO:0034653 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.0 0.0 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.0 0.2 GO:0060242 contact inhibition(GO:0060242)
0.0 0.1 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.1 GO:0060700 regulation of ribonuclease activity(GO:0060700)
0.0 0.0 GO:0045553 TRAIL biosynthetic process(GO:0045553) regulation of TRAIL biosynthetic process(GO:0045554) positive regulation of TRAIL biosynthetic process(GO:0045556)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.1 GO:0009368 endopeptidase Clp complex(GO:0009368)
0.0 0.1 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
0.1 0.3 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.0 0.1 GO:0032129 histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969)
0.0 0.1 GO:0048040 UDP-glucuronate decarboxylase activity(GO:0048040)
0.0 0.2 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.1 GO:0035473 lipase binding(GO:0035473)
0.0 0.0 GO:0004947 bradykinin receptor activity(GO:0004947)
0.0 0.2 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.0 0.1 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.0 0.1 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.1 GO:0051920 peroxiredoxin activity(GO:0051920)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.3 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation