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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for ZNF410

Z-value: 0.35

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Transcription factors associated with ZNF410

Gene Symbol Gene ID Gene Info
ZNF410
ENSG00000119725.13 zinc finger protein 410

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZNF410hg19_v2_chr14_+_74353574_74353589-0.371.1e-01Click!

Activity profile of ZNF410 motif

Sorted Z-values of ZNF410 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_6716569 3.13 ENST00000544040.1
ENST00000545942.1
CHD4
chromodomain helicase DNA binding protein 4
chr12_-_6716534 1.54 ENST00000544484.1
ENST00000309577.6
ENST00000357008.2
CHD4
chromodomain helicase DNA binding protein 4
chr12_-_122241812 0.38 ENST00000538335.1
AC084018.1
AC084018.1
chr7_+_2695726 0.38 ENST00000429448.1
TTYH3
tweety family member 3
chr5_-_176900610 0.32 ENST00000477391.2
ENST00000393565.1
ENST00000309007.5
DBN1
drebrin 1
chr18_-_59274139 0.32 ENST00000586949.1
RP11-879F14.2
RP11-879F14.2
chr8_-_57233103 0.23 ENST00000303749.3
ENST00000522671.1
SDR16C5
short chain dehydrogenase/reductase family 16C, member 5
chr4_-_83933999 0.22 ENST00000510557.1
LIN54
lin-54 homolog (C. elegans)
chr4_-_83934078 0.20 ENST00000505397.1
LIN54
lin-54 homolog (C. elegans)
chr22_-_39268192 0.19 ENST00000216083.6
CBX6
chromobox homolog 6
chr11_-_57334732 0.18 ENST00000526659.1
ENST00000527022.1
UBE2L6
ubiquitin-conjugating enzyme E2L 6
chr12_+_122241928 0.12 ENST00000604567.1
ENST00000542440.1
SETD1B
SET domain containing 1B
chr18_-_14970301 0.10 ENST00000580867.1
RP11-527H14.3
RP11-527H14.3
chr2_+_70121075 0.06 ENST00000409116.1
SNRNP27
small nuclear ribonucleoprotein 27kDa (U4/U6.U5)
chr19_+_47840346 0.05 ENST00000600626.1
C5AR2
complement component 5a receptor 2
chr8_-_4852494 0.01 ENST00000520002.1
ENST00000602557.1
CSMD1
CUB and Sushi multiple domains 1

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF410

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 4.7 GO:0072553 terminal button organization(GO:0072553)
0.1 0.3 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.0 0.1 GO:0038178 complement component C5a signaling pathway(GO:0038178) negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024) negative regulation of neutrophil migration(GO:1902623)
0.0 0.2 GO:0032020 ISG15-protein conjugation(GO:0032020)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.7 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.7 GO:0031492 ATP-dependent DNA helicase activity(GO:0004003) nucleosomal DNA binding(GO:0031492)
0.0 0.1 GO:0004878 complement component C5a receptor activity(GO:0004878)
0.0 0.2 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.3 GO:0005522 profilin binding(GO:0005522)
0.0 0.4 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 4.7 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1