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SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for ZNF423

Z-value: 0.39

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Transcription factors associated with ZNF423

Gene Symbol Gene ID Gene Info
ZNF423
ENSG00000102935.7 zinc finger protein 423

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZNF423hg19_v2_chr16_-_49890016_49890046-0.126.1e-01Click!

Activity profile of ZNF423 motif

Sorted Z-values of ZNF423 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_14772810 1.14 ENST00000295092.2
ENST00000331243.4
FAM84A
family with sequence similarity 84, member A
chr5_+_150400124 1.02 ENST00000388825.4
ENST00000521650.1
ENST00000517973.1
GPX3
glutathione peroxidase 3 (plasma)
chr17_+_7341586 0.72 ENST00000575235.1
FGF11
fibroblast growth factor 11
chr19_-_11689752 0.68 ENST00000592659.1
ENST00000592828.1
ENST00000218758.5
ENST00000412435.2
ACP5
acid phosphatase 5, tartrate resistant
chr9_+_112542591 0.61 ENST00000483909.1
ENST00000314527.4
ENST00000413420.1
ENST00000302798.7
ENST00000555236.1
ENST00000510514.5
PALM2
PALM2-AKAP2
AKAP2
paralemmin 2
PALM2-AKAP2 readthrough
A kinase (PRKA) anchor protein 2
chr4_+_152330390 0.51 ENST00000503146.1
ENST00000435205.1
FAM160A1
family with sequence similarity 160, member A1
chr20_-_36794938 0.51 ENST00000453095.1
TGM2
transglutaminase 2
chr7_+_20370300 0.47 ENST00000537992.1
ITGB8
integrin, beta 8
chr20_-_36794902 0.46 ENST00000373403.3
TGM2
transglutaminase 2
chr9_-_130659569 0.43 ENST00000542456.1
ST6GALNAC6
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr16_-_11681023 0.40 ENST00000570904.1
ENST00000574701.1
LITAF
lipopolysaccharide-induced TNF factor
chr15_+_41523417 0.39 ENST00000560397.1
CHP1
calcineurin-like EF-hand protein 1
chr9_+_112542572 0.38 ENST00000374530.3
PALM2-AKAP2
PALM2-AKAP2 readthrough
chr4_+_4388805 0.38 ENST00000504171.1
NSG1
Homo sapiens neuron specific gene family member 1 (NSG1), transcript variant 3, mRNA.
chr7_-_30029328 0.37 ENST00000425819.2
ENST00000409570.1
SCRN1
secernin 1
chr4_+_4388245 0.37 ENST00000433139.2
NSG1
Homo sapiens neuron specific gene family member 1 (NSG1), transcript variant 3, mRNA.
chr5_+_154181816 0.35 ENST00000518677.1
LARP1
La ribonucleoprotein domain family, member 1
chr19_-_10679644 0.34 ENST00000393599.2
CDKN2D
cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
chr16_+_27324983 0.32 ENST00000566117.1
IL4R
interleukin 4 receptor
chr4_+_4387983 0.32 ENST00000397958.1
NSG1
Homo sapiens neuron specific gene family member 1 (NSG1), transcript variant 3, mRNA.
chr17_+_36584662 0.31 ENST00000431231.2
ENST00000437668.3
ARHGAP23
Rho GTPase activating protein 23
chr12_+_57522692 0.31 ENST00000554174.1
LRP1
low density lipoprotein receptor-related protein 1
chr3_-_52931557 0.31 ENST00000504329.1
ENST00000355083.5
TMEM110-MUSTN1
TMEM110
TMEM110-MUSTN1 readthrough
transmembrane protein 110
chr9_-_130659679 0.30 ENST00000373141.1
ST6GALNAC6
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr3_-_195808952 0.30 ENST00000540528.1
ENST00000392396.3
ENST00000535031.1
ENST00000420415.1
TFRC
transferrin receptor
chr16_+_27325202 0.30 ENST00000395762.2
ENST00000562142.1
ENST00000561742.1
ENST00000543915.2
ENST00000449195.1
ENST00000380922.3
ENST00000563002.1
IL4R
interleukin 4 receptor
chr8_+_22022800 0.29 ENST00000397814.3
BMP1
bone morphogenetic protein 1
chr3_-_195808980 0.29 ENST00000360110.4
TFRC
transferrin receptor
chr13_-_46626847 0.29 ENST00000242848.4
ENST00000282007.3
ZC3H13
zinc finger CCCH-type containing 13
chr2_+_135011731 0.29 ENST00000281923.2
MGAT5
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
chr7_-_23053693 0.28 ENST00000409763.1
ENST00000409923.1
FAM126A
family with sequence similarity 126, member A
chr1_+_24118452 0.28 ENST00000421070.1
LYPLA2
lysophospholipase II
chr4_+_152330409 0.28 ENST00000513086.1
FAM160A1
family with sequence similarity 160, member A1
chr6_-_32160622 0.28 ENST00000487761.1
ENST00000375040.3
GPSM3
G-protein signaling modulator 3
chr13_-_46626820 0.28 ENST00000428921.1
ZC3H13
zinc finger CCCH-type containing 13
chr22_+_35653445 0.28 ENST00000420166.1
ENST00000444518.2
ENST00000455359.1
ENST00000216106.5
HMGXB4
HMG box domain containing 4
chr3_+_107244229 0.27 ENST00000456419.1
ENST00000402163.2
BBX
bobby sox homolog (Drosophila)
chr7_+_20370746 0.26 ENST00000222573.4
ITGB8
integrin, beta 8
chr19_-_4066890 0.26 ENST00000322357.4
ZBTB7A
zinc finger and BTB domain containing 7A
chr11_-_61659006 0.26 ENST00000278829.2
FADS3
fatty acid desaturase 3
chr11_-_61658853 0.26 ENST00000525588.1
ENST00000540820.1
FADS3
fatty acid desaturase 3
chr9_+_116638630 0.26 ENST00000452710.1
ENST00000374124.4
ZNF618
zinc finger protein 618
chr12_+_57522439 0.25 ENST00000338962.4
LRP1
low density lipoprotein receptor-related protein 1
chr1_-_204121102 0.25 ENST00000367202.4
ETNK2
ethanolamine kinase 2
chr3_-_69129501 0.24 ENST00000540295.1
ENST00000415609.2
ENST00000361055.4
ENST00000349511.4
UBA3
ubiquitin-like modifier activating enzyme 3
chr11_-_44972418 0.24 ENST00000525680.1
ENST00000528290.1
ENST00000530035.1
TP53I11
tumor protein p53 inducible protein 11
chr8_+_22022653 0.23 ENST00000354870.5
ENST00000397816.3
ENST00000306349.8
BMP1
bone morphogenetic protein 1
chr12_-_54779511 0.23 ENST00000551109.1
ENST00000546970.1
ZNF385A
zinc finger protein 385A
chr22_-_43045574 0.22 ENST00000352397.5
CYB5R3
cytochrome b5 reductase 3
chr19_+_6740888 0.22 ENST00000596673.1
TRIP10
thyroid hormone receptor interactor 10
chr19_+_20011775 0.21 ENST00000592245.1
ENST00000592160.1
ENST00000343769.5
AC007204.2
ZNF93
AC007204.2
zinc finger protein 93
chr1_-_204121013 0.21 ENST00000367201.3
ETNK2
ethanolamine kinase 2
chr1_-_33366931 0.21 ENST00000373463.3
ENST00000329151.5
TMEM54
transmembrane protein 54
chr12_+_7342271 0.21 ENST00000434354.2
ENST00000544456.1
ENST00000545574.1
ENST00000420616.2
PEX5
peroxisomal biogenesis factor 5
chr11_-_107729504 0.20 ENST00000265836.7
SLC35F2
solute carrier family 35, member F2
chr8_+_22022223 0.20 ENST00000306385.5
BMP1
bone morphogenetic protein 1
chr11_+_61595752 0.19 ENST00000521849.1
FADS2
fatty acid desaturase 2
chr2_+_171785824 0.19 ENST00000452526.2
GORASP2
golgi reassembly stacking protein 2, 55kDa
chr22_-_37823468 0.19 ENST00000402918.2
ELFN2
extracellular leucine-rich repeat and fibronectin type III domain containing 2
chr19_+_20011731 0.19 ENST00000591366.1
ZNF93
zinc finger protein 93
chr1_-_204121298 0.19 ENST00000367199.2
ETNK2
ethanolamine kinase 2
chr3_-_48594248 0.19 ENST00000545984.1
ENST00000232375.3
ENST00000416568.1
ENST00000383734.2
ENST00000541519.1
ENST00000412035.1
PFKFB4
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
chr4_+_71570430 0.19 ENST00000417478.2
RUFY3
RUN and FYVE domain containing 3
chr12_-_57522813 0.18 ENST00000556155.1
STAT6
signal transducer and activator of transcription 6, interleukin-4 induced
chr18_+_77867177 0.18 ENST00000560752.1
ADNP2
ADNP homeobox 2
chr6_+_33589161 0.18 ENST00000605930.1
ITPR3
inositol 1,4,5-trisphosphate receptor, type 3
chr19_-_15311713 0.17 ENST00000601011.1
ENST00000263388.2
NOTCH3
notch 3
chr6_-_143266297 0.17 ENST00000367603.2
HIVEP2
human immunodeficiency virus type I enhancer binding protein 2
chr12_+_7342441 0.16 ENST00000412720.2
ENST00000396637.3
PEX5
peroxisomal biogenesis factor 5
chr11_-_47207950 0.16 ENST00000298838.6
ENST00000531226.1
ENST00000524509.1
ENST00000528201.1
ENST00000530513.1
PACSIN3
protein kinase C and casein kinase substrate in neurons 3
chr11_+_61595572 0.16 ENST00000517312.1
FADS2
fatty acid desaturase 2
chr7_-_23053719 0.16 ENST00000432176.2
ENST00000440481.1
FAM126A
family with sequence similarity 126, member A
chr2_+_171785012 0.16 ENST00000234160.4
GORASP2
golgi reassembly stacking protein 2, 55kDa
chr6_-_91296737 0.15 ENST00000369332.3
ENST00000369329.3
MAP3K7
mitogen-activated protein kinase kinase kinase 7
chr2_+_46770531 0.13 ENST00000482449.2
RHOQ
ras homolog family member Q
chr21_+_45432174 0.13 ENST00000380221.3
ENST00000291574.4
TRAPPC10
trafficking protein particle complex 10
chr11_-_44972299 0.13 ENST00000528473.1
TP53I11
tumor protein p53 inducible protein 11
chr16_+_30675654 0.12 ENST00000287468.5
ENST00000395073.2
FBRS
fibrosin
chr10_+_135340859 0.12 ENST00000252945.3
ENST00000421586.1
ENST00000418356.1
CYP2E1
cytochrome P450, family 2, subfamily E, polypeptide 1
chr11_+_60691924 0.12 ENST00000544065.1
ENST00000453848.2
ENST00000005286.4
TMEM132A
transmembrane protein 132A
chr4_-_166034029 0.12 ENST00000306480.6
TMEM192
transmembrane protein 192
chr9_+_130160440 0.12 ENST00000439597.1
ENST00000423934.1
SLC2A8
solute carrier family 2 (facilitated glucose transporter), member 8
chr19_-_36391434 0.12 ENST00000396901.1
ENST00000585925.1
NFKBID
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta
chr4_-_120548779 0.11 ENST00000264805.5
PDE5A
phosphodiesterase 5A, cGMP-specific
chr6_+_151187074 0.11 ENST00000367308.4
MTHFD1L
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
chr8_+_145065521 0.11 ENST00000534791.1
GRINA
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
chr5_+_141303461 0.11 ENST00000508751.1
KIAA0141
KIAA0141
chr4_+_74735102 0.11 ENST00000395761.3
CXCL1
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
chr5_+_135385202 0.11 ENST00000514554.1
TGFBI
transforming growth factor, beta-induced, 68kDa
chr4_-_166034004 0.11 ENST00000505095.1
TMEM192
transmembrane protein 192
chr9_+_139249228 0.10 ENST00000392944.1
GPSM1
G-protein signaling modulator 1
chr7_+_101460882 0.10 ENST00000292535.7
ENST00000549414.2
ENST00000550008.2
ENST00000546411.2
ENST00000556210.1
CUX1
cut-like homeobox 1
chr17_+_28705921 0.10 ENST00000225719.4
CPD
carboxypeptidase D
chr1_-_35658736 0.10 ENST00000357214.5
SFPQ
splicing factor proline/glutamine-rich
chr6_-_91296602 0.10 ENST00000369325.3
ENST00000369327.3
MAP3K7
mitogen-activated protein kinase kinase kinase 7
chr7_-_30029367 0.09 ENST00000242059.5
SCRN1
secernin 1
chr9_-_99381660 0.09 ENST00000375240.3
ENST00000463569.1
CDC14B
cell division cycle 14B
chr16_+_70148230 0.09 ENST00000398122.3
ENST00000568530.1
PDPR
pyruvate dehydrogenase phosphatase regulatory subunit
chr17_-_73178599 0.09 ENST00000578238.1
SUMO2
small ubiquitin-like modifier 2
chr6_+_151186554 0.08 ENST00000367321.3
ENST00000367307.4
MTHFD1L
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
chrX_-_51239425 0.08 ENST00000375992.3
NUDT11
nudix (nucleoside diphosphate linked moiety X)-type motif 11
chr19_+_41770269 0.08 ENST00000378215.4
HNRNPUL1
heterogeneous nuclear ribonucleoprotein U-like 1
chr9_+_131549610 0.08 ENST00000223865.8
TBC1D13
TBC1 domain family, member 13
chr11_+_73019282 0.07 ENST00000263674.3
ARHGEF17
Rho guanine nucleotide exchange factor (GEF) 17
chr20_+_43514320 0.07 ENST00000372839.3
ENST00000428262.1
ENST00000445830.1
YWHAB
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
chr19_+_41770349 0.07 ENST00000602130.1
HNRNPUL1
heterogeneous nuclear ribonucleoprotein U-like 1
chr19_-_5292781 0.07 ENST00000586065.1
PTPRS
protein tyrosine phosphatase, receptor type, S
chr6_+_142468361 0.06 ENST00000367630.4
VTA1
vesicle (multivesicular body) trafficking 1
chr17_-_1029052 0.06 ENST00000574437.1
ABR
active BCR-related
chr17_-_48227877 0.06 ENST00000316878.6
PPP1R9B
protein phosphatase 1, regulatory subunit 9B
chr14_-_93582214 0.06 ENST00000556603.2
ENST00000354313.3
ITPK1
inositol-tetrakisphosphate 1-kinase
chrX_-_107019181 0.06 ENST00000315660.4
ENST00000372384.2
ENST00000502650.1
ENST00000506724.1
TSC22D3
TSC22 domain family, member 3
chr8_+_145065705 0.06 ENST00000533044.1
GRINA
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
chr13_+_21277482 0.05 ENST00000304920.3
IL17D
interleukin 17D
chr8_+_22422749 0.05 ENST00000523900.1
SORBS3
sorbin and SH3 domain containing 3
chr4_-_152329987 0.05 ENST00000508847.1
RP11-610P16.1
RP11-610P16.1
chr2_+_62932779 0.05 ENST00000427809.1
ENST00000405482.1
ENST00000431489.1
EHBP1
EH domain binding protein 1
chr3_+_180630444 0.05 ENST00000491062.1
ENST00000468861.1
ENST00000445140.2
ENST00000484958.1
FXR1
fragile X mental retardation, autosomal homolog 1
chr10_+_85933494 0.05 ENST00000372126.3
C10orf99
chromosome 10 open reading frame 99
chr19_-_23941639 0.05 ENST00000395385.3
ENST00000531570.1
ENST00000528059.1
ZNF681
zinc finger protein 681
chr12_-_118810688 0.04 ENST00000542532.1
ENST00000392533.3
TAOK3
TAO kinase 3
chr19_+_10531150 0.04 ENST00000352831.6
PDE4A
phosphodiesterase 4A, cAMP-specific
chr19_+_41770236 0.04 ENST00000392006.3
HNRNPUL1
heterogeneous nuclear ribonucleoprotein U-like 1
chr18_-_60985914 0.04 ENST00000589955.1
BCL2
B-cell CLL/lymphoma 2
chr1_-_48462566 0.03 ENST00000606738.2
TRABD2B
TraB domain containing 2B
chr8_+_22423168 0.03 ENST00000518912.1
ENST00000428103.1
SORBS3
sorbin and SH3 domain containing 3
chr4_+_128982490 0.03 ENST00000394288.3
ENST00000432347.2
ENST00000264584.5
ENST00000441387.1
ENST00000427266.1
ENST00000354456.3
LARP1B
La ribonucleoprotein domain family, member 1B
chrX_-_107018969 0.03 ENST00000372383.4
TSC22D3
TSC22 domain family, member 3
chr6_+_168841817 0.03 ENST00000356284.2
ENST00000354536.5
SMOC2
SPARC related modular calcium binding 2
chr7_-_5570229 0.03 ENST00000331789.5
ACTB
actin, beta
chr7_-_27219632 0.03 ENST00000470747.4
RP1-170O19.20
Uncharacterized protein
chr19_-_11689803 0.03 ENST00000591319.1
ACP5
acid phosphatase 5, tartrate resistant
chr6_-_31080336 0.03 ENST00000259870.3
C6orf15
chromosome 6 open reading frame 15
chr4_+_128982430 0.03 ENST00000512292.1
ENST00000508819.1
LARP1B
La ribonucleoprotein domain family, member 1B
chr19_+_20011744 0.02 ENST00000588146.1
ZNF93
zinc finger protein 93
chr5_+_72509751 0.02 ENST00000515556.1
ENST00000513379.1
ENST00000427584.2
RP11-60A8.1
RP11-60A8.1
chr20_+_43514315 0.02 ENST00000353703.4
YWHAB
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
chr16_+_3014269 0.02 ENST00000575885.1
ENST00000571007.1
ENST00000319500.6
KREMEN2
kringle containing transmembrane protein 2
chr11_-_44972476 0.02 ENST00000527685.1
ENST00000308212.5
TP53I11
tumor protein p53 inducible protein 11
chr19_-_23941680 0.01 ENST00000402377.3
ZNF681
zinc finger protein 681
chr8_-_133493200 0.01 ENST00000388996.4
KCNQ3
potassium voltage-gated channel, KQT-like subfamily, member 3
chr9_+_116638562 0.01 ENST00000374126.5
ENST00000288466.7
ZNF618
zinc finger protein 618
chr11_-_1036706 0.01 ENST00000421673.2
MUC6
mucin 6, oligomeric mucus/gel-forming
chr1_+_17914907 0.01 ENST00000375420.3
ARHGEF10L
Rho guanine nucleotide exchange factor (GEF) 10-like
chr1_+_55271736 0.01 ENST00000358193.3
ENST00000371273.3
C1orf177
chromosome 1 open reading frame 177
chr14_-_93582148 0.01 ENST00000267615.6
ENST00000553452.1
ITPK1
inositol-tetrakisphosphate 1-kinase
chr12_+_7037461 0.01 ENST00000396684.2
ATN1
atrophin 1
chr21_-_45682099 0.00 ENST00000270172.3
ENST00000418993.1
DNMT3L
DNA (cytosine-5-)-methyltransferase 3-like
chr12_-_50101003 0.00 ENST00000550488.1
FMNL3
formin-like 3
chr8_-_42234745 0.00 ENST00000220812.2
DKK4
dickkopf WNT signaling pathway inhibitor 4

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF423

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0018262 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.1 1.0 GO:0006982 response to lipid hydroperoxide(GO:0006982)
0.1 0.6 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.1 0.4 GO:0070893 transposon integration(GO:0070893) regulation of transposon integration(GO:0070894) negative regulation of transposon integration(GO:0070895)
0.1 0.6 GO:0045626 negative regulation of T-helper 1 cell differentiation(GO:0045626)
0.1 0.7 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.1 0.2 GO:0007113 endomitotic cell cycle(GO:0007113)
0.1 1.1 GO:0098887 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887)
0.1 0.3 GO:0072752 cellular response to rapamycin(GO:0072752)
0.0 0.2 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.0 1.5 GO:0001573 ganglioside metabolic process(GO:0001573)
0.0 0.3 GO:0070885 positive regulation of sodium:proton antiporter activity(GO:0032417) negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.0 0.2 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.0 0.2 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.0 0.3 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0 0.2 GO:1901093 regulation of protein tetramerization(GO:1901090) negative regulation of protein tetramerization(GO:1901091) regulation of protein homotetramerization(GO:1901093) negative regulation of protein homotetramerization(GO:1901094)
0.0 0.2 GO:1902162 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.0 0.6 GO:0045780 positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.0 0.3 GO:0048102 autophagic cell death(GO:0048102)
0.0 0.3 GO:0002084 protein depalmitoylation(GO:0002084)
0.0 0.7 GO:0034380 high-density lipoprotein particle assembly(GO:0034380)
0.0 0.2 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.1 GO:0034164 negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.0 0.6 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.1 GO:0010193 response to ozone(GO:0010193)
0.0 0.1 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.0 0.1 GO:0070245 positive regulation of thymocyte apoptotic process(GO:0070245)
0.0 0.1 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.0 0.1 GO:1901911 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.0 0.2 GO:0072104 glomerulus vasculature morphogenesis(GO:0072103) glomerular capillary formation(GO:0072104)
0.0 0.3 GO:0036109 alpha-linolenic acid metabolic process(GO:0036109) linoleic acid metabolic process(GO:0043651)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.1 1.1 GO:0098845 postsynaptic endosome(GO:0098845)
0.0 0.3 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 0.6 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.4 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559) cytoplasmic side of late endosome membrane(GO:0098560)
0.0 0.3 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.3 GO:0016589 NURF complex(GO:0016589)
0.0 0.3 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.2 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.2 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.2 0.6 GO:0072510 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.2 0.6 GO:0016964 alpha-2 macroglobulin receptor activity(GO:0016964)
0.2 0.6 GO:0004913 interleukin-4 receptor activity(GO:0004913)
0.1 1.1 GO:0032051 clathrin light chain binding(GO:0032051)
0.1 0.2 GO:0019781 NEDD8 activating enzyme activity(GO:0019781)
0.1 0.7 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 1.0 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 0.6 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.1 0.3 GO:0016213 linoleoyl-CoA desaturase activity(GO:0016213)
0.0 1.0 GO:0008430 selenium binding(GO:0008430)
0.0 0.3 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.2 GO:0000822 inositol hexakisphosphate binding(GO:0000822) inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.7 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.2 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.0 0.2 GO:0004331 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 0.1 GO:0047325 inositol tetrakisphosphate 1-kinase activity(GO:0047325) inositol-1,3,4-trisphosphate 6-kinase activity(GO:0052725) inositol-1,3,4-trisphosphate 5-kinase activity(GO:0052726) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) inositol-3,4,6-trisphosphate 1-kinase activity(GO:0052835)
0.0 0.3 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.3 GO:0008494 translation activator activity(GO:0008494)
0.0 0.2 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 0.3 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.2 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.1 GO:0052843 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.0 0.1 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 0.5 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.1 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.4 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.2 GO:0019855 calcium channel inhibitor activity(GO:0019855)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.7 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 1.0 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.2 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.6 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.2 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.2 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.2 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.3 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism