Project
SARS-CoV-2 Analysis Results (GEO series: GSE147507)
Navigation
Downloads
Results for ZNF711_TFAP2A_TFAP2D
Z-value: 6.50
Motif logo
Transcription factors associated with ZNF711_TFAP2A_TFAP2D
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
| ENSG00000147180.12 | zinc finger protein 711 | |
| ENSG00000137203.6 | transcription factor AP-2 alpha | |
| ENSG00000008197.4 | transcription factor AP-2 delta |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| ZNF711 | hg19_v2_chrX_+_84499081_84499115 | 0.93 | 3.6e-09 | Click! |
| TFAP2A | hg19_v2_chr6_-_10415470_10415508 | -0.57 | 8.3e-03 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr15_+_27112058 Show fit | 20.13 |
ENST00000355395.5
|
gamma-aminobutyric acid (GABA) A receptor, alpha 5 |
|
| chr2_+_121493717 Show fit | 19.37 |
ENST00000418323.1
|
GLI family zinc finger 2 |
|
| chr15_+_27112194 Show fit | 19.04 |
ENST00000555182.1
|
gamma-aminobutyric acid (GABA) A receptor, alpha 5 |
|
| chr15_+_27112296 Show fit | 18.50 |
ENST00000554038.1
|
gamma-aminobutyric acid (GABA) A receptor, alpha 5 |
|
| chr15_+_27112380 Show fit | 18.26 |
ENST00000554596.1
|
gamma-aminobutyric acid (GABA) A receptor, alpha 5 |
|
| chr2_-_233792837 Show fit | 17.51 |
ENST00000373552.4
ENST00000409079.1 |
neuronal guanine nucleotide exchange factor |
|
| chr7_-_131241361 Show fit | 17.32 |
ENST00000378555.3
ENST00000322985.9 ENST00000541194.1 ENST00000537928.1 |
podocalyxin-like |
|
| chr15_+_27112251 Show fit | 16.34 |
ENST00000400081.3
|
gamma-aminobutyric acid (GABA) A receptor, alpha 5 |
|
| chr1_-_226595648 Show fit | 15.50 |
ENST00000366790.3
|
poly (ADP-ribose) polymerase 1 |
|
| chr3_-_5229982 Show fit | 15.40 |
ENST00000600805.1
|
Uncharacterized protein |
Network of associatons between targets according to the STRING database.
First level regulatory network of ZNF711_TFAP2A_TFAP2D
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.1 | 172.5 | GO:0007052 | mitotic spindle organization(GO:0007052) |
| 2.8 | 114.7 | GO:0007214 | gamma-aminobutyric acid signaling pathway(GO:0007214) |
| 2.1 | 85.6 | GO:0034080 | CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641) |
| 1.1 | 52.0 | GO:0007077 | mitotic nuclear envelope disassembly(GO:0007077) |
| 2.7 | 51.5 | GO:0034501 | protein localization to kinetochore(GO:0034501) |
| 1.6 | 50.7 | GO:0006855 | drug transmembrane transport(GO:0006855) |
| 1.8 | 50.4 | GO:0031915 | positive regulation of synaptic plasticity(GO:0031915) |
| 1.7 | 47.0 | GO:0032201 | telomere maintenance via semi-conservative replication(GO:0032201) |
| 2.3 | 43.4 | GO:0051310 | metaphase plate congression(GO:0051310) |
| 3.6 | 43.3 | GO:0032286 | central nervous system myelin maintenance(GO:0032286) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 159.3 | GO:0005739 | mitochondrion(GO:0005739) |
| 1.2 | 148.9 | GO:0000779 | condensed chromosome, centromeric region(GO:0000779) |
| 0.3 | 142.9 | GO:0005759 | mitochondrial matrix(GO:0005759) |
| 3.7 | 114.3 | GO:1902711 | GABA-A receptor complex(GO:1902711) |
| 0.6 | 90.6 | GO:0000922 | spindle pole(GO:0000922) |
| 0.7 | 71.2 | GO:0031526 | brush border membrane(GO:0031526) |
| 0.9 | 70.0 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
| 1.0 | 69.3 | GO:0009295 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
| 0.8 | 64.3 | GO:0032592 | integral component of mitochondrial membrane(GO:0032592) |
| 0.6 | 61.6 | GO:0005901 | caveola(GO:0005901) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 135.1 | GO:0019787 | ubiquitin-like protein transferase activity(GO:0019787) |
| 3.9 | 116.1 | GO:0050811 | GABA receptor binding(GO:0050811) |
| 0.2 | 98.4 | GO:0005525 | GTP binding(GO:0005525) |
| 0.4 | 95.4 | GO:0008017 | microtubule binding(GO:0008017) |
| 0.4 | 90.5 | GO:0042393 | histone binding(GO:0042393) |
| 0.7 | 72.7 | GO:0003777 | microtubule motor activity(GO:0003777) |
| 0.4 | 61.0 | GO:0004386 | helicase activity(GO:0004386) |
| 1.1 | 57.0 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
| 0.4 | 56.7 | GO:0017048 | Rho GTPase binding(GO:0017048) |
| 0.5 | 55.7 | GO:0004722 | protein serine/threonine phosphatase activity(GO:0004722) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.8 | 149.6 | PID AURORA B PATHWAY | Aurora B signaling |
| 1.8 | 135.4 | PID FANCONI PATHWAY | Fanconi anemia pathway |
| 1.6 | 115.6 | PID PLK1 PATHWAY | PLK1 signaling events |
| 0.9 | 100.1 | PID ILK PATHWAY | Integrin-linked kinase signaling |
| 0.7 | 87.3 | PID ERA GENOMIC PATHWAY | Validated nuclear estrogen receptor alpha network |
| 0.6 | 79.6 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.9 | 72.5 | ST GA13 PATHWAY | G alpha 13 Pathway |
| 0.8 | 67.4 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.9 | 55.2 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
| 1.3 | 53.9 | PID ATR PATHWAY | ATR signaling pathway |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.5 | 230.4 | REACTOME MITOTIC PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 4.1 | 118.1 | REACTOME GABA A RECEPTOR ACTIVATION | Genes involved in GABA A receptor activation |
| 0.4 | 82.4 | REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |
| 1.0 | 77.1 | REACTOME TRIGLYCERIDE BIOSYNTHESIS | Genes involved in Triglyceride Biosynthesis |
| 1.3 | 74.9 | REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS | Genes involved in Thrombin signalling through proteinase activated receptors (PARs) |
| 3.6 | 71.7 | REACTOME UNWINDING OF DNA | Genes involved in Unwinding of DNA |
| 1.5 | 61.0 | REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
| 1.1 | 60.2 | REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS | Genes involved in TGF-beta receptor signaling activates SMADs |
| 0.9 | 54.2 | REACTOME GLUCONEOGENESIS | Genes involved in Gluconeogenesis |
| 0.7 | 53.0 | REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC | Genes involved in Regulation of ornithine decarboxylase (ODC) |